ERNESTO GARCÍA-URETA

XXII EUROPEAN CONGRESS OF CYTOLOGY Madrid 2007

METÁSTASIS PULMONARES por MIOMA UTERINO

CITOLOGÍAA PROPÓSITO DE UN CASO

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A 41-year old woman

Hysterectomy…………..Myomas

Multiple Pulmonary Nodules

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MULTIPLE LUNG NODULES

METASTATIC DISEASE

Saroidosis

Lung Infections:

• Mycobacteria

• Fungi

• Nococardia

• Septic emboli

Amyloidosis

Rheumatoid Nodules

Arteriovenous malformations

Hamartomas

Smooth Muscle Tumors

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Lymphangioleiomyomatosis

Multiple Pulmonary Leiomyomatous Hamartomas

Benign Metastasizing Leiomyoma

Actin

MIB-1

ESTROGEN

HMB-45

S - 100

HMB - 45

ESTROGEN

PROGESTERONE

Steiner P.l.

Metastazing fibroleiomyoma of the

uterus. Am J. Pathol. 1939; 15: 89-109

Benign Metastasizing Leiomyoma of the Uterus Esteban JM. et all.

Arch Pathol Lab Med. 1999; 123: 960-2

Benign Pulmonary metastasizing Leiomyoma of the Uterus Egberts JH. et all.

Arch Gynecol Obstet. 2006; 29:

Benign metastasizing LeiomyomaPatton KT. et all.

Mod pthol. 2006; 19:130-40

Benign metastasizing Leiomyoma of the lungPawlik C. et all.

Dtsch Med Wochenschr. 2001; 11:551-5

Benign metastasizing LeiomyomaTietze L. et all.

Hum Pathol. 2000; 31:126-8

SPINDLE CELLS

IN LUNG FNA

BLAND

APPEARING

INFLAMMATORY BACKGROUND

ATYPICALL /

PLEOMORPHIC

NO INFLAMMATORY

BACKGROUND

PREDOMINANT SPINDLE CELLS

MIXED SPINDLE AND EPITHELIOID

CELLS

CYTOKERATINA + S100 +

CARCINOSARCOMA ANAPLASTIC CARCINOMA

SYNOVIAL SARCOMA BIPHASIC

MELANOMA

CYTOKERATIN + S100 + SMA + VIMENTIN +

MFHLEIOMYOSARCOMAMELANOMA MPNST

SARCOMATOID CARCINOMA

SPINDLE CELL CARCINOID

SYNOVIAL SARCOMA

MONOPHASIC

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