Boston sci

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  • Intravascular Ultrasound for Plaque CharacterizationScott R. SmithBoston Scientific Corporation

    The 3rd Vulnerable Plaque SymposiumMarch 16, 2002

  • Who needs interventional diagnosis and treatment?Summary ofNational Heart, Lung, and Blood InstituteWorkshop on Cardiovascular Risk Assessment

    Population

    Size

    Annual Risk

    Healthy People

    Huge

  • Diagnosis of Vulnerable Plaqueselecting a populationTotal100at risk 10treated 14saved9unnecessary 5missed 1

  • Plaque StructureCourtesy of Dr. Renu VirmaniArmed Forces Institute of Pathology

  • IVUS Plaque Imaging Ruptured plaque

  • Boston Scientific Imaging SystemsFeatures & Intended BenefitsTapered tip; 2.5 Fr. Crossing ProfileHigh definition 40MHz IVUS catheter. 6F Guide Catheter Compatibility.

    Atlantis SR Plus CatheterGalaxy IVUS System

  • Galaxy System Features and Intended Benefits Time-Saving FeaturesImage BookmarkingLongView longitudinal measurementsPullback sled

    Enhanced Ease of UseTraceAssist automatic lumen trace functionAngiographic compatibilityPush button control

  • Galaxy System Research CapabilitiesExpanded FunctionalityDigital image storagePatient databasePre/post intervention analysis.

    RF OutputDirect Access to RF signal for acquisition and analysisFuture plans may include direct RF signal acquisition

  • Imaging vs. AnalysisRFRectified and Log compressedLow passed filtered - 10MHzOne image vector

  • Other Imaging ModalitiesIndependenceSpatial resolution Contrast

    IVUS

    acoustic impedance

    MRI

    proton relaxation

    Thermal

    temperature

    OCT

    refractive index

    Spectroscopy

    chemical bonds

  • ConclusionIntravascular Ultrasound currently widely used for intravascular imagingBroad potential for plaque volume measurement and tissue characterizationVariety of research efforts aimed at improving tissue contrast and resolution

    Thanks to: Tat Jin Teo, PhD - BSC ImagingRenu Virmani, MD - AFIPJay Kokate, PhD - BSC Applied Research