AN INTRIGUING NUTRACEUTICAL APPROACH IN DOGS AFFECTED BY KERATOCONJUNCTIVITIS SICCA · 2018. 3....
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AN INTRIGUING NUTRACEUTICAL APPROACH IN DOGS AFFECTED BY KERATOCONJUNCTIVITIS SICCA The Korean Society of Veterinary Ophthalmology (KSVO) 2014, March 22 nd 23 rd ABSTRACT Palmieri B 1 2 , MD, PhD; Destefanis S 2 ., DVM, ENV; Giretto D 2 ., DVM, ENV; Muscolo C 2 ., DVM, PhD; Di Cerbo A 2 ., PhD; Guidetti G 2 ., MSc; Canello S 2 ., DVM 1 University of Modena, School of Medicine, Italy 2 AIRMO Research and development Center, Milan, Italy Keratoconjunctivitis sicca (KCS) is a corneo-conjunctiva progressive inflammatory disease affecting domestic animals with tears production impairment and several ocular symptoms triggered by autoimmune imbalance. Cyclosporine and tacrolimus ointment, steroids drops and artificial tears is the gold standard treatment. Our study is addressed to evaluate the complementary role of a 2 months, administered nutraceutical food, in dogs whose immuno-suppressive treatment had proven unadequate. The formula encloses fish proteins, rice carbohydrates, mellon superoxid dismutase, Ascophyllum nodosum, Astaxantina, Aloe vera, Carica papaya, Punica granatum, Green tea, Polygonum L., Curcuma longa, Piper nigrum, Zinc and a Omega3/6 ratio of 1:0.8. The trial involved two group of animals: in the first group, unsatisfactorily responsive to the integrative feeding, after 30 days, the complementary effect of the functional food, joined with the local treatment, gave 120% Schirmer Test improvement and reduction of mean conjunctivitis intensity: 70%, cheratitis lesions: 65%, corneal pigmentation: 50% and mucus production 80%. In the second group exclusively cured with the long term diet administration, a drop out of intraocular treatment was attempted to evaluate if functional feeding would support prolonged or permanent control of the symptoms. In 45% animals it was possible to definitely withdraw immunosuppressive treatment, with artificial tears administration follow up. The ongoing study is investigating whether the exclusion of the nutraceutical food might be responsible of KCS relapse or not. Right Eye BEFORE Right Eye AFTER Left Eye BEFORE Left Eye AFTER Right Eye BEFORE Right Eye AFTER CASE n° 1 CASE n° 2 CASE n° 3 Left Eye BEFORE Left Eye AFTER Left Eye BEFORE Left Eye AFTER CASE n° 4 Right Eye AFTER Right Eye BEFORE
Transcript of AN INTRIGUING NUTRACEUTICAL APPROACH IN DOGS AFFECTED BY KERATOCONJUNCTIVITIS SICCA · 2018. 3....
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AN INTRIGUING NUTRACEUTICAL APPROACH IN DOGS AFFECTED
BY KERATOCONJUNCTIVITIS SICCA
The Korean Society of Veterinary Ophthalmology (KSVO) 2014, March 22nd 23rd
ABSTRACT
Palmieri B1 2, MD, PhD; Destefanis S 2., DVM, ENV; Giretto D2., DVM, ENV; Muscolo C 2., DVM, PhD; Di Cerbo A2., PhD; Guidetti G2., MSc; Canello S 2., DVM
1 University of Modena, School of Medicine, Italy2 AIRMO Research and development Center, Milan, Italy
Keratoconjunctivitis sicca (KCS) is a corneo-conjunctiva progressive inflammatory disease affecting domestic animals with tears production impairment and several ocular symptoms triggered by autoimmune imbalance. Cyclosporine and tacrolimus ointment, steroids drops and artificial tears is the gold standard treatment. Our study is addressed to evaluate the complementary role of a 2 months, administered nutraceutical food, in dogs whose immuno-suppressive treatment had proven unadequate. The formula encloses fish proteins, rice carbohydrates, mellon superoxid dismutase, Ascophyllum nodosum, Astaxantina, Aloe vera, Carica papaya, Punica granatum, Green tea, Polygonum L., Curcuma longa, Piper nigrum, Zinc and a Omega3/6 ratio of 1:0.8. The trial involved two group of animals: in the first group, unsatisfactorily responsive to the integrative feeding, after 30 days, the complementary effect of the functional food, joined with the local treatment, gave 120% Schirmer Test improvement and reduction of mean conjunctivitis intensity: 70%, cheratitis lesions: 65%, corneal pigmentation: 50% and mucus production 80%. In the second group exclusively cured with the long term diet administration, a drop out of intraocular treatment was attempted to evaluate if functional feeding would support prolonged or permanent control of the symptoms. In 45% animals it was possible to definitely withdraw immunosuppressive treatment, with artificial tears administration follow up. The ongoing study is investigating whether the exclusion of the nutraceutical food might be responsible of KCS relapse or not.
Right Eye BEFORE
Right Eye AFTER
Left Eye BEFORE
Left Eye AFTER
Right Eye BEFORE
Right Eye AFTER
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