Post on 15-Mar-2019
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Karen Tong, M.D.
Imaging of Otalgia at 12 amKaren Tong, MD. Associate Professor
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Karen Tong, M.D.
Imaging of Otalgia at 12 am
https://apkgk.com/com.OneLife2Care.BabiesEarInfectionHelp
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Karen Tong, M.D.
Objectives
• Review neurosensory pathways of ear pain • Review causes of otalgia (especially urgent/important ones)
• Case presentations
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Karen Tong, M.D.
Recommended references:
• Weissman JL. “A pain in the ear: the radiology of otalgia.” AJNR 1997 Oct;18(9):1641-51.
• Scarbrough TJ, et al. “Referred otalgia in head and neck cancer: a unifying schema.” Am J Clin Oncol. 2003 Oct;26(5):e157-62.
• Chen RC, Khorsandi AS, Shatzkes DR, Holliday RA. “The radiology of referred otalgia.” AJNR 2009 Nov;30(10):1817-23.
• Dr. Lindell Gentry’s lecture, “Imaging of Otalgia”, ASHNR 2013 • Cranial nerve lectures from: Drs.Lindell Gentry, John Go, Wendy Smoker
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Karen Tong, M.D.
Classification of otalgia
• Primary: ear pain resulting from pathologic conditions of the ear itself
• Secondary: pain referred to the ear from nonotologic sites, usually in the distributions of cranial nerves V, VII, IX, or X; or the cervical plexus
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Primary otalgia
• In children, most cases of otalgia are primary. • In adults, less than half of the cases of otalgia are primary.
• Usually have clinical findings on exam • Simple otitis does not require imaging • If needed, temporal bone CT usually imaging of choice
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Primary otalgia - etiologies• EAC disease
• Carbuncle or furuncle (folliculitis)
• Acute otitis externa (swimmer’s ear)
• Necrotizing (malignant OE) – urgent, pseudomonas
• Cholesteatoma, CA – dull pain • Foreign bodies, trauma
• Middle ear disease • Acute otitis media,
otomastoiditis – with complications
• Petrous apicitis (Gradenigo’s syndrome)
• Cholesteatoma • Eustachian tube
dysfunction, barotrauma
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Secondary otalgia• “Convergence-projection theory”: multiple nerves converge on
single shared neural pathway, but CNS unable to differentiate origin of stimulation (sensory error)
• Identifying cause of secondary otalgia may be challenging due to complex innervation of the ear and many potential sources of referred pain.
• May be due to non-otologic lesions that are innervated along shared pathway, or direct pathology of a shared nerve (“neuralgia”)
• Otoscopic exam usually normal; imaging may include CT and MRI
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Sensory innervation by location Sensory innervation by nerve Click to edit Master title style
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Sensory innervation of outer ear
Hutchens et al, “Ear Anesthesia”, Medscape 6/14/18
(V3)
(C2)
(C2,C3)
(X)
Dr. Mahmoud, ENT, Ain Shans University
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Sensory innervation to TM and ME
• Outer/lateral side of TM – auriculotemporal nerve
• Middle ear/medial side of TM – glossopharyngeal component of tympanic plexus (Jacobson’s nerve)
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Sensory innervation of inner ear
• Primarily by vestibulocochlear nerve, but does not have pain fibers
• Can have pathology of the inner ear without pain
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Secondary otalgia - etiologies• Dental: infection, malocclusion, TMJ • Inflammatory: sinonasal, oral, retro/pharyngeal, laryngeal, salivary (esp. parotid), temporal arteritis, neuralgia (e.g. Ramsay Hunt, neuralgias (trigeminal, sphenopalatine, N. intermedius, IX, X) chronic paroxsymal hemicrania, migraine, longus colli tendinitis, carotidynia
• Neoplasm: sinonasal, oral, retro/pharyngeal, laryngeal, salivary, lung
• Miscellaneous: Eagle’s, GERD
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Innervation of referred ear pain is complex:
• 4 cranial nerves (V,VII, IX and X)
• 2 cervical nerves (C2, C3)
• Possibly cervical sympathetic fibers
Chen RC, Khorsandi AS, Shatzkes DR, Holliday RA. The radiology of referred otalgia. AJNR Am J Neuroradiol. 2009
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Referred otalgia from CN V
Chen RC, Khorsandi AS, Shatzkes DR, Holliday RA. The radiology of referred otalgia. AJNR Am J Neuroradiol. 2009
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Referred otalgia from CN V
• Auriculotemporal N. • Dental disease (most common cause from V3, usually mandibular molars)
• TMJ dz (70-80% pts) • Parotid infection/inflammation
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Referred otalgia from CN VII
Chen RC, Khorsandi AS, Shatzkes DR, Holliday RA. The radiology of referred otalgia. AJNR Am J Neuroradiol. 2009
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Referred otalgia from CN VII• Posterior auricular N. • Posterior ethmoid and sphenoid sinus inflammation
• Septal spurs irritating nasal mucosa
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Referred otalgia from CN IX
Chen RC, Khorsandi AS, Shatzkes DR, Holliday RA. The radiology of referred otalgia. AJNR Am J Neuroradiol. 2009
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Referred otalgia from CN IX
• Jacobson’s N. • Acute tonsillitis, peritonsillar abscess
• Oropharyngeal CA – otalgia can be early symptom
• Eagle syndrome (but only 4% pts w elongated styloid have symptoms)
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Referred otalgia from CN X
Chen RC, Khorsandi AS, Shatzkes DR, Holliday RA. The radiology of referred otalgia. AJNR Am J Neuroradiol. 2009
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Referred otalgia from CN X
• Arnold’s N. • Laryngeal CA • Lung CA • Crycoaretynoid inflammation
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CASE PRESENTATIONS
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Case: 12 yo male w ear pain, fever, seizure
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12 yo male w ear pain, fever, seizure Click to edit Master title style
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Dx: temporal lobe abscess due to otomastoiditis
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Case: 61 yo male w DM, otalgia and ataxia Click to edit Master title style
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Dx: cerebellar abscess due to otomastoiditis
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Acute otomastoiditis & complications• Coalescent mastoiditis • Subperiosteal abscess - periauricular • Intracranial abscess – middle cranial or posterior fossa;
epidural or parenchymal, subdural empyema • Meningitis • Infarction • Sinus thrombosis - usually sigmoid and/or IJV • Labyrinthitis • Petrous apicitis • Bezold abscess
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Case: 84-year-old female w ear/jaw pain
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Dx: Malignant/Necrotizing Otitis Externa Click to edit Master title style
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Malignant/Necrotizing Otitis Externa• Rare complication of otitis externa that spreads to skull base and causes osteomyelitis
• Usually due to pseudomonas aeruginosa but can be fungal (aspergillus, mucor)
• Sx: severe otalgia, facial nerve palsy, also CN IX to XII • Usually elderly diabetics, but increasingly seen with immunocompromise (HIV)
• Can be life-threatening if there are intracranial complications
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Case: 12 mo old w bilateral otalgia, ear drainage Click to edit Master title style
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Dx: T-bone Langerhan Cell Histiocytosis
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T-bone Langerhans Cell Histiocytosis
• Usually in children < 10 yo • Histiocytic tumor-like proliferation • Otologic symptoms in 25% cases: conductive hearing loss, otorrhea, otalgia, periauricular soft tissue swelling, CN VII palsy
• Soft tissue mass w osseous destruction, may have fluid-fluid levels
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Case: 62 yo male w otalgia, plugged ear
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Case: 10 yo w severe ear/facial pain, sound sensitivity Click to edit Master title style
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Nasopharyngeal tumors
• Can obstruct eustachian tube and cause otitis and ear pain
• In adults: NPC most common • In children: rhabdomyosarcoma most common
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Case: 30 yo w facial, jaw and ear pain Click to edit Master title style
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Dental infection
• Dental infections are a frequent cause of referred otalgia
• Pain from molars, especially mandibular molars, radiates to the ear
• Include: dental caries, acute periapical abscess, perimandibular abscess
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Cases: ear pain, sore throat, fever
Dx: retropharyngeal abscess
Dx: tonsillitis Dx: peritonsillar abscess
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Tonsillar & Retropharyngeal infection
• Severe ear pain is one hallmark of peritonsillar abscess
• Diseases of retropharyngeal nodes (of Rouviere) can present with otalgia
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Case: 14 yo w ear/facial pain, swelling Click to edit Master title style
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Case: 3 yo w periauricular swelling and ear pain
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Parotid infection
• Acute parotiditis presents w marked periauricular tenderness and fever; can be associated with cellulitis, abscess is rare
• Recurrent parotid abscess in child should suggest underlying 1st branchial cleft cyst
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Summary
• Most ear pain in children arises from primary otologic source • Otalgia can be a pain to diagnose, especially if secondarily referred from a non-otologic source
• Referred pain can travel along shared neural pathways involving CNs V, VII, IX, X; cervical nerves C2, C3, and possibly cervical sympathetic fibers
• Source of pain can range from sinonasal to lung • Diagnostic steps may include: clinical → CT → MRI