Three Types of Muscle Tissues Skeletal Muscle usually attached to bones under conscious control...

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Three Types of Muscle Tissues Skeletal Muscle • usually attached to bones • under conscious control • striated Smooth Muscle • walls of most viscera, blood vessels, skin • not under conscious control • not striated Cardiac Muscle • wall of heart • not under conscious control • striated Chapter 9 - Muscular Chapter 9 - Muscular System System

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Transcript of Three Types of Muscle Tissues Skeletal Muscle usually attached to bones under conscious control...

Page 1: Three Types of Muscle Tissues Skeletal Muscle usually attached to bones under conscious control striated Smooth Muscle walls of most viscera, blood vessels,

Three Types of Muscle Tissues

Skeletal Muscle• usually attached to bones• under conscious control• striated

Smooth Muscle• walls of most viscera, blood vessels, skin• not under conscious control• not striated

Cardiac Muscle• wall of heart• not under conscious control• striated

Chapter 9 - Muscular Chapter 9 - Muscular SystemSystem

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Skeletal Muscle• organ of the muscular system• skeletal muscle tissue• nervous tissue• blood• connective tissues• fascia• tendon• aponeuroses

Structure of a Skeletal Structure of a Skeletal MuscleMuscle

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• epimysium• perimysium• fascicle• endomysium

• muscle• fascicles• muscle fibers• myofibrils• thick and thin filaments

Structure of a Skeletal Structure of a Skeletal MuscleMuscle

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• sarcolemma• sacroplasm• sarcoplasmic reticulum• transverse tubule• triad

• cisterna of sarcoplasmic reticulum• transverse tubule

• myofibril• actin filaments• myosin filaments• sarcomere

Skeletal Muscle FiberSkeletal Muscle Fiber

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Structure of a Skeletal Structure of a Skeletal MuscleMuscle

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• I band• A band• H zone• Z line• M line

SarcomereSarcomere

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Thick Filaments • composed of myosin• cross-bridges

Thin Filaments• composed of actin• associated with troponin and tropomyosin

MyofilamentsMyofilaments

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• site where axon and muscle fiber communicate• motor neuron• motor end plate• synaptic cleft• synaptic vesicles• neurotransmitters

Neuromuscular Neuromuscular JunctionJunction

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• single motor neuron• all muscle fibers controlled by motor neuron

Motor UnitMotor Unit

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• acetylcholine (ACh)• nerve impulse causes release of acetylcholine from synaptic vesicles• binds to acetylcholine receptors on motor end plate• generates a muscle impulse• muscle impulse eventually reaches sarcoplasmic reticulum

Stimulus for Stimulus for ContractionContraction

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• muscle impulses cause sarcoplasmic reticulum to release calcium ions into cytosol• calcium binds to troponin to change its shape• position of tropomyosin is altered• binding sites on actin exposed• actin and myosin bind

Excitation Contraction Excitation Contraction CouplingCoupling

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• When sarcromeres shorten, thick and thin filaments slide past one another• H zones and I bands get narrower• Z lines move closer together

Sliding Filament Sliding Filament TheoryTheory

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• actin and myosin cross-bridge bind

• myosin cross-bridge pulls actin

•ADP and phosphate released from myosin

• new ATP binds to myosin

• linkage between actin and myosin cross-bridge break

•ATP splits

•myosin cross-bridge goes back to original position

Cross-bridge CyclingCross-bridge Cycling

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• acetylcholinesterase – breaks down acetylcholine• muscle impulse stops• calcium moves back into sarcoplasmic reticulum• myosin and actin binding prevented

RelaxationRelaxation

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• creatine phosphate – stores energy that quickly converts ADP to ATP

1) Creatine phosphate 2) Cellular respiration

Energy Sources for Energy Sources for ContractionContraction

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• Anaerobic Phase• glycolysis• produces little ATP

• Aerobic Phase• citric acid cycle• electron transport chain• produces most ATP • myoglobin stores extra oxygen

Oxygen Supply and Oxygen Supply and Cellular RespirationCellular Respiration

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• oxygen not available• glycolysis continues• pyruvic acid converted to lactic acid• liver converts lactic acid to glucose

Oxygen debt – amount of oxygen needed by liver to convert lactic acid to glucose

Oxygen DebtOxygen Debt

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• inability to contract• commonly caused from

• decreased blood flow• ion imbalances• accumulation of lactic acid

• cramp – sustained, involuntary contraction

Muscle FatigueMuscle Fatigue

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• by-product of cellular respiration• muscle cells are major source of body heat• blood transports heat throughout body

Heat ProductionHeat Production

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Threshold Stimulus• minimal strength required to cause contraction

Recording a Muscle Contraction

• twitch• latent period• period of contraction• period of relaxation• refractory period• all-or-none response

Muscular ResponsesMuscular Responses

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• process by which individual twitches combine• produces sustained contractions• can lead to tetanic contractions

SummationSummation

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• recruitment - increase in the number of motor units activated

• whole muscle composed of many motor units

• as intensity of stimulation increases, recruitment of motor units continues until all motor units are activated

Recruitment of Motor Recruitment of Motor UnitsUnits

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• smaller motor units recruited first• larger motor units recruited later• produces smooth movements• muscle tone – continuous state of partial contraction

Sustained Sustained ContractionsContractions

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• isotonic – muscle contracts and changes length

• concentric – shortening contraction

• eccentric – lengthening contraction

• isometric – muscle contracts but does not change length

Types of ContractionsTypes of Contractions

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Slow-twitch fibers (type I)• always oxidative• resistant to fatigue• red fibers • most myoglobin• good blood supply

Fast-twitch glycolytic fibers (type II)• white fibers (less myoglobin)• poorer blood supply• susceptible to fatigue

Fast-twitch fatigue-resistant fibers (type IIb)

• intermediate fibers• oxidative• intermediate amount of myoglobin• pink to red in color

Fast and Slow Twitch Fast and Slow Twitch Muscle FibersMuscle Fibers

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Compared to skeletal muscle fibers• shorter• single nucleus• elongated with tapering ends• myofilaments randomly organized• no striations• lack transverse tubules• sarcoplasmic reticula not well developed

Smooth Muscle FibersSmooth Muscle Fibers

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Visceral Smooth Muscle• single-unit smooth muscle• sheets of muscle fibers• fibers held together by gap junctions• exhibit rhythmicity• exhibit peristalsis• walls of most hollow organs

Multiunit Smooth Muscle• fibers function separately• irises of eye• walls of blood vessels

Types of Smooth Types of Smooth MuscleMuscle

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• Resembles skeletal muscle contraction• interaction between actin and myosin• both use calcium and ATP• both depend on impulses

• Different from skeletal muscle contraction• smooth muscle lacks troponin• smooth muscle depends on calmodulin • two neurotransmitters affect smooth muscle

• acetlycholine and norepinephrine• hormones affect smooth muscle• stretching can trigger smooth muscle contraction• smooth muscle slower to contract and relax• smooth muscle more resistant to fatigue

Smooth Muscle Smooth Muscle ContractionContraction

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• only in the heart• muscle fibers joined together by intercalated discs• fibers branch• network of fibers contracts as a unit• self-exciting and rhythmic• longer refractory period than skeletal muscle

Cardiac MuscleCardiac Muscle

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• origin – immovable end• insertion – movable end

• prime mover (agonist) – primarily responsible for movement• synergists – assist prime mover• antagonist – resist prime mover’s action and cause movement in the opposite direction

Skeletal Muscle Skeletal Muscle ActionsActions

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Major Skeletal Major Skeletal MusclesMuscles

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Major Skeletal Major Skeletal MusclesMuscles

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Muscles of Facial Muscles of Facial ExpressionExpression

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Muscles of Muscles of MasticationMastication

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Muscles of Facial Muscles of Facial Expression and Expression and

MasticationMastication

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Muscles That Move the Muscles That Move the Head and Vertebral Head and Vertebral

ColumnColumn

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Muscles That Move the Muscles That Move the Pectoral GirdlePectoral Girdle

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Muscles That Move the Muscles That Move the ArmArm

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Deep Muscles of the Deep Muscles of the Back and NeckBack and Neck

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Muscles of the Muscles of the Shoulder and BackShoulder and Back

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Muscles of the Anterior Muscles of the Anterior Chest and Abdominal Chest and Abdominal

WallWall

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Muscles That Move the Muscles That Move the ForearmForearm

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Muscles That Move the Muscles That Move the HandHand

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Muscles of the Muscles of the Shoulder and ArmShoulder and Arm

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Cross Section of the Cross Section of the ArmArm

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Muscles of the Muscles of the Shoulder and ArmShoulder and Arm

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Muscles of the Muscles of the Arm and ForearmArm and Forearm

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Muscles of the Muscles of the Arm and ForearmArm and Forearm

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Cross Section of the Cross Section of the ForearmForearm

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Muscles of the Muscles of the Abdominal WallAbdominal Wall

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Muscles of the Abdominal Muscles of the Abdominal WallWall

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Muscles of the Pelvic Muscles of the Pelvic OutletOutlet

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Muscles of Pelvic Outlets Muscles of Pelvic Outlets and Urogenital and Urogenital

DiaphragmDiaphragm

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Muscles That Move the Muscles That Move the ThighThigh

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Muscles That Move the Muscles That Move the LegLeg

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Muscles That Move the Muscles That Move the FootFoot

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Muscles of the Thigh and Muscles of the Thigh and LegLeg

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Muscles of the Thigh and Muscles of the Thigh and LegLeg

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Muscles of the Thigh and Muscles of the Thigh and LegLeg

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Cross Section of the Cross Section of the ThighThigh

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Muscles of the LegMuscles of the Leg

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Muscles of the LegMuscles of the Leg

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Muscles of the LegMuscles of the Leg

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Cross Section of the Cross Section of the LegLeg

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• myoglobin, ATP, and creatine phosphate decline• by age 80, half of muscle mass has atrophied• adipose cells and connective tissues replace muscle tissue• exercise helps to maintain muscle mass and function

Life-Span ChangesLife-Span Changes

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Myasthenia Gravis

• autoimmune disorder• receptors for acetylcholine on muscle cells are attacked• weak and easily fatigued muscles result• difficulty swallowing and chewing• ventilator needed if respiratory muscles are affected• treatments include

• drugs that boost acetylcholine• removing thymus gland• immunosuppressant drugs• antibodies

Clinical ApplicationClinical Application

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Active vs. Inactive Muscle: Active vs. Inactive Muscle: Muscular AtrophyMuscular Atrophy

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Exercise and Diet Exercise and Diet Stimulates Muscle Stimulates Muscle

DevelopmentDevelopment

Arnold Schwarzenegger – Body Arnold Schwarzenegger – Body Builder, Actor, and PoliticianBuilder, Actor, and Politician Hans and FranzHans and Franz


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MUSCLE TISSUE Muscle Contraction TYPES OF MUSCLE TISSUE A. Skeletal muscle -voluntary muscle, striated with light and dark bands, many nuclei per cell.

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An invertebrate smooth muscle with striated muscle … · An invertebrate smooth muscle with striated muscle myosin filaments Guidenn Sulbarána,b,1, Lorenzo Alamoa,1, Antonio Pintoa,

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Function depends on structure. Muscle classification 1.Striated muscle A.Skeletal Muscle - voluntary muscles that allow for movement B.Cardiac Muscle.

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Muscle Structure Animal Growth and Development. Types of Muscle ► Skeletal ► Cardiac ► Smooth ► Classification Striated Non-striated Voluntary

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(a) Skeletal muscle (b) Smooth muscle - MIT OpenCourseWare · PDF fileSkeletal (striated) and smooth muscle Temporal patterns of muscle contraction • • • max) l (a) Skeletal

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