RAMC 2007 1

Company Background

Founded 2003 Focus on protein crystallography

RAMC 2007 2

Products

Intelli-plates Family of sitting drop plates

Phoenix Protein crystallography robot

CrysCam Digital microscope and image capture

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Intelli-Plates

Original Intelli-Plate Improved design just released

Improved optics Easier crystal harvesting

Round bottom wells Well volumes

2.5µl and 8µl

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Intelli-Plates

4.0µL 1.0µL

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Intelli-Plates

Intelli-Plate 3-well Round bottom wells Three 1 µL wells

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Intelli-Plate

0.2µL 0.5µL 1.0µL

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Intelli-Plates

Intelli-Plate 48 well plates SBS footprint Manual setup and 8-channel span liquid

handler set up Round bottom wells Well volume

2-well:4µL and 20µL 3-well: Three 4µL

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Phoenix

Protein crystallization robot

Introduced in 2005 Over 80 systems

world wide

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Phoenix

Sets up hanging drop, sitting drop and microbatch reactions

96-well head for dispensing screen compounds

1-channel head for dispensing of protein

9 position deck

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Phoenix

Features & benefits Protein drop exposure < 60 seconds Dispenses screen and protein Bench-top lab use: footprint of 25 x 27

inches Easy to use drag and drop software

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Phoenix

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Phoenix

96-channel head Positive displacement glass syringes Aspirates and dispenses a wide range

of viscosities Volumes 100 nL to 100µL Flexible needles Low maintenance No disposable costs

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Phoenix

1-channel head Fast on-the-fly dispensing Dispense down to 50nL Dispense up to 7.5% PEG 8000 No system liquid to dilute protein

sample

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CrysCam

Affordable digital microscope

Capture 96 images in 3 minutes

Compatible with most 24,48 and 96-well

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CrysCam

CrysCam features Small foot print X-Y stage resolution .027mm Zoom lens with iris Polarization USB 2.0 megapixel camera

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CrysCam

CrysScore software Score and comment images Score image over a network XML data files