Krok 2 · the substance of potassium acetate. What reagent conﬁrms the presence of potassium...

Sample test questions

Krok 2 Pharmacy

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Фармацевтична хiмiя 2

1. An analyst of a chemical laboratoryhad received a glucose substance foranalysis. To check its quality he used apolarimeter. The analyst measured:

A. Angle of rotationB. Refractive indexC. Optical densityD. Melting pointE. Specific gravity

2. The analytical laboratory receivedcalcium chloride. What volumetricsolution should be used for quantitativedetermination of this medicinal substance?

A. Sodium edetateB. Potassium bromateC. Hydrochloric acidD. Potassium permanganateE. Sodium hydroxide

3. An analytical chemist of a centralindustrial laboratory performs quantitativedetermination of penicillin sum inbenzylpenicillin sodium salt by means ofiodometric method. What indicator is used?

A. StarchB. PhenolphthaleinC. Potassium chromateD. Methyl orangeE. Methyl red

4. Paracetamol substance has been sentfor analysis. Reaction with the solution ofiron (III) chloride resilted in the blue-violetcoloring. This indicates the presence of:

A. Phenolic hydroxylB. Aldehyde groupC. Keto groupD. Ester groupE. Alcoholic hydroxyl

5. An analytical laboratory has receiveda procaine hydrochloride substancefor analysis. According to the StatePharmacopoeia of Ukraine limit content ofheavy metals should be determined with thefollowing reagent:

A. ThioacetamideB. Methoxyphenylacetic acidC. HypophosphiteD. Aminomethyl alizarin acetic acidE. Sulfomolybdenum

6. Chloride of lime is identified by calciumcations after boiling with acetic acid in orderto eliminate active chlorine. What reagent isused?

A. Ammonium oxalateB. Magnesium sulfateC. Potassium chlorideD. Sodium nitriteE. Ammonium molybdate

7. Optical rotation angle of substances isdetermined under the temperature of 20oC,in 1-decimeter-thick layer, with wavelengthof sodium spectrum D-lines (λ = 589.3 nm),and is calculated with reference to a solutioncontaining 1 g of the substance per ml. It iscalled:

A. Specific optical rotationB. Optical densityC. Refractive indexD. Relative densityE. Distribution coefficient

8. Which of the following antibiotics can beidentified by means of maltol test?

A. Streptomycin sulfateB. Doxycycline hydrochlorideC. AmoxicillinD. Lincomycin hydrochlorideE. Kanamycin monosulfate

9. A pharmaceutical analyst identifiesthe substance of potassium acetate. Whatreagent confirms the presence of potassiumcation in the substance?

A. Tartaric acidB. Sodium hydroxideC. Potassium permanganateD. Iron (III) chlorideE. Zinc oxide

10. An analytical chemist performs thequalitative assessment of mercury (II)chloride. What method is recommended bythe State Pharmacopoeia of Ukraine forquantitative assessment in this case?

A. Complexometric titrationB. Nitritometric titrationC. BromatometryD. AlkalimetryE. Acidimetry

11. An analytical chemist investigates a3% hydrogen solution. What reagent isrecommended by the State Pharmacopoeiaof Ukraine for identification of thissubstance?

A. Potassium chromateB. Sodium chlorideC. Magnesium sulfateD. Calcium chlorideE. Zinc oxide

12. Benzoic acid is known to have antisepticproperties. To identify this acid the followingshould be used:


A. FeCl3B. [NH4]2C2O4C. K2[HgI4]D. K2CrO4E. KMnO4

13. An analytical chemist analyses thesubstance of racemic menthol according tothe State Pharmacopoeia of Ukraine. Toidentify the drug and determine its purity hemeasures optical rotation that should occurwithin the interval:

A. From +0.2o to -0.2o

B. From -48o to -51o

C. From +50o to +56o

D. From +10o to +13o

E. From -102o to -105o

14. Presence of phenolic hydroxyl in thestructure of pyridoxine hydrochloride canbe confirmed by application of the followingsolution:

A. Iron (III) clorideB. Potassium permanganateC. Sodium sulfateD. Silver nitrateE. Sodium nitrite

15. An analytical chemist can quantitativelydetermine the thiamine bromide content inpowders by means of:

A. AlkalimetryB. Nitritometric titrationC. BromometryD. PermanganatometryE. Complexometric titration

16. Quantitative content of theophylline canbe determined by alkalimetric titration ofnitric acid that is quantitatively obtained asthe result of the following theophylline saltproduction:

A. SilverB. PotassiumC. SodiumD. AmmoniumE. Lithium

17. In the process of isoniazid identificationa pharmacy analyst thoroughly boiled thesubstance with 2,4-dinitrochlorobenzene.The substance turned yellow. After addingalkaline solution the substance turned firstviolet and then brownish-red. As the resultof this reaction the following aldehydederivative is produced:

A. GlutaconicB. GluconicC. GlutamicD. GlyoxylicE. Hexanic

18. What method is recommended bythe State Pharmacopoeia of Ukraine forquantitative determination of potassiumchloride substance that is used in treatmentof hypokalemia?

A. ArgentometryB. BromatometryC. IodometryD. CerimetryE. Polarimetry

19. During limit test for aluminiumadmixture, the State Pharmacopoeia ofUkraine recommends to use the followingsolution as the basic reagent:

A. HydroxyquinolineB. Sodium tetraphenylborateC. Thioglycolic acidD. Sodium hypophosphiteE. Barium chloride

20. Presence of nitrate radical inmetronidazole structure can be confirmedby reduction of nitrate radical to aminogroup with production of:

A. Azo dyeB. IndophenolC. ThiochromeD. IodoformE. Murexide

21. Xycaine quantitative content can bedetermined by means of argentometry (backtitration). What indicator is required by thismethod?

A. Iron (III) ammonium sulphateB. Sodium eosinateC. Bromphenol blueD. StarchE. Potassium chromate

22. An analytical chemist performsquantitative analysis of isoniazid by meansof direct bromatometry with volumetricsolutions of potassium bromate, potassiumbromide, hydrochloric acid and methyl redas an indicator. This method is based on thefollowing reaction:


A. Oxidation of the hydrazine group withbromineB. Reduction of the hydrazine residue withbromineC. Oxidation of the hydrazine residue withpotassium bromideD. Opening of the pyridine ringE. Bromination of the pyridine ring

23. The main method of quantitativedetermination of corticosteroids is:

A. SpectrophotometryB. PotentiometryC. CerimetryD. ArgentometryE. Acidimetry

24. According to the State Pharmacopoeiaof Ukraine, an analytical chemistdetermines quantitative content ofpotassium acetate by means of acidimetry innon-aqueous medium. Name the volumetricsolution in this case:

A. Perchloric acidB. IodineC. Potassium bromateD. Sodium hydroxideE. Sodium nitrite

25. The chemical name of 2,2-(diphenylmethoxy)-N,N-dimethyl-ethanaminehydrochloride corresponds with thefollowing medicinal substance:

A. Diphenhydramine hydrochlorideB. Ethylmorphine hydrochlorideC. Lidocaine hydrochlorideD. Ciprofloxacin hydrochlorideE. Papaverine hydrochloride

26. An analytical chemist should use thefollowing solution to identify sodium-containing substances:

A. Potassium pyroantimonateB. Potassium permanganateC. Sodium citrateD. Potassium carbonateE. Barium hydroxide

27. An analytical chemist performs collargolidentification by means of ashing. Obtainedresidue is then dissolved in hydrochloricacid. Specify the analytical effect that isobserved in this case:

A. White precipitateB. Black precipitateC. Yellow precipitateD. Blue precipitateE. Light green precipitate

28. Calcium gluconate is being testedfor presence of admixtures of saccharoseand reducing sugars with copper-tartrate

reagent. If these admixtures are present thesubstance colors:

A. RedB. BlueC. GreenD. TurquoiseE. White

29. The analyst determines quantitativecontent of sodium benzoate by meansof acidimetry in non-aqueous mediumaccording to the State Pharmacopoeia ofUkraine. What reagent is used as a solventin this case?

A. Anhydrous acetic acidB. PyridineC. Concentrated sulfuric acidD. Dimethyl formamideE. Sulfanilic acid

30. What antibiotic has beta-lactam cycle inits structure?

A. Benzylpenicillin potassium saltB. Doxycycline hyclateC. ChloramphenicolD. Streptomycin sulfateE. Lincomycin hydrochloride

31. The chemical name of 2-benzyl-1H-benzimidazole hydrochloride correspondswith the following medicinal substance:

A. Dibazol (Bendazolum)B. OmeprazoleC. IndometacinD. PhenazepamE. Vicasol (Menadione)

32. Identification of potassium iodiderequires performing an oxidation reactionin acid medium, which produces free iodinethat colors chloroform layer. What reagentis used for such a reaction?

A. Sodium nitriteB. Silver nitrateC. Barium chlorideD. Sodium carbonateE. Ammonium oxalate

33. An analytical chemist determinespotassium ions admixture in a medicinalsubstance with sodium tetraphenylborateaccording to the State Pharmacopoeiaof Ukraine. What analytical effect wouldconfirm the presence of this admixture?

A. White opalescenceB. Yellow coloringC. Blue coloringD. Pink coloringE. Brown coloring

34. What corticosteroid medicinal substance


has two fluorine atoms in its chemicalstructure?

A. Fluocinolone acetonideB. DexamethasoneC. Triamcinolone acetonideD. PrednisoloneE. Hydrocortisone acetate

35. A private pharmacy received a supplyof a drug with 2.3-dihydro-2-methyl-1.4-naphthoquinone-2-sulfonate sodium as anactive ingredient. Name this drug:

A. Vicasol (Menadione)B. RutinC. RiboflavinD. ErgocalciferolE. Cocarboxylase hydrochloride

36. The reaction of glucose identificationproduces red precipitate with the followingreagent:

A. Copper-tartrateB. Thiocyanogen bromideC. Ammoniacal silver nitrate solutionD. Alkaline potassium tetraiodomercuratesolutionE. Sodium nitroprusside solution

37. During quantitative determination ofVicasol (Menadione) by means of cerimetry,the following indicator is used:

A. FerroinB. NaphtholbenzeinC. Crystal violetD. Methyl orangeE. Methyl red

38. As the result of reduction of alcoholicsolutions of 5-nitrofuran derivatives bymeans of their reaction with zinc in thepresence of diluted hydrochloric acid, thefollowing occurs:

A. Solution decolorationB. PrecipitationC. Ammonia productionD. Color change from yellow to blackE. Precipitation and gassing

39. A certain drug explodes when heatedto 180oC or upon impact and, therefore,must be handled carefully during receipt andstorage. This drug is:

A. Nitroglycerine solutionB. Activated carbonC. Alcoholic iodine solutionD. Barium chlorideE. Calcium chloride

40. A certain drug can be quantitativelyassessed by means of direct alkalimetryin glycerine, mannitol, or other polyhydric

alcohol medium. This drug is:

A. Boric acidB. Benzoic acidC. Salicylic acidD. Glutaminic acidE. Acetylsalicylic acid

41. Bromatometry allows quantitativeanalysis of the following drug:

A. Sodium salicylateB. Glutamic acidC. β-AlanineD. Benzoic acidE. Potassium acetate

42. What drug, due to β-lactam ring inits structure, has positive reaction withhydroxylamine hydrochloride solution inthe presence of sodium hydroxide withsubsequent addition of iron (III) chloridesolution?

A. Amoxicillin trihydrateB. MetronidazoleC. Papaverine hydrochlorideD. PhenazoneE. Dibazol (Bendazol)

43. A technological controller uses Marquisreagent to identify the substance ofacetylsalicylic acid after acid hydrolysis.Positive effect of the reaction would beindicated by the following coloring:

A. PinkB. BlueC. YellowD. GreenE. Violet

44. Nicotinamide is a pyridine derivative,which can be identified by its positivereaction with:

A. Cyanogen bromide reagentB. Copper-tartrate solutionC. Grade reagentD. Thioacetamide reagentE. Thioglycolic acid solution

45. According to the State Pharmacopoeiaof Ukraine, an analytical chemist shoulduse acidimetry in non-aqueous mediumto determine quantitative content of thefollowing purine alkaloid:

A. CaffeineB. TheobromineC. Caffeine and sodium benzoateD. Theophylline ethylenediamineE. Theophylline

46. An analytical chemist performsidentification of lidocaine hydrochloride.According to the State Pharmacopoeia of


Ukraine the presence of chloride ions can beconfirmed by means of reaction with silvernitrate solution resulting in:

A. White caseous precipitateB. Green fluorescenceC. Violet coloringD. Yellow precipitateE. Blue coloring

47. According to the State Pharmacopoeiaof Ukraine, an analytical chemist candetermine sulfate admixtures in sodiumtetraborate by the effect of whiteopalescence that results from its reactionwith the following solution:

A. Barium chlorideB. Ammonium oxalateC. Magnesium sulfateD. Sodium sulfideE. Silver nitrate

48. According to the State Pharmacopoeiaof Ukraine quantitative content of salicylicacid is to be determined by means of:

A. AlkalimetryB. Nitritometric titrationC. Complexometric titrationD. AcidimetryE. Argentometry

49. An analytical chemist conductsquantitative determination of ibuprofen(substance) by means of direct alkalimetry.The following solution will be an indicatorin this case:

A. PhenolphthaleinB. Tropeolin 00C. Mordant blackD. Potassium chromateE. Ammonium iron (III) sulfate

50. What indicator is used in iodometry forquantitative determination of caffeine incaffeine and sodium benzoate?

A. StarchB. Potassium chromateC. Eriochrome blackD. Methyl orangeE. Bromthymol blue

51. To identify pilocarpine hydrochlorideit is necessary to use reaction with sodiumnitroprusside in an alkaline medium(Legal’s test). Resulting cherry-red coloringconfirms presence of the following in thepilocarpine structure:

A. Lactonic ringB. Imidazole ringC. Methylene groupD. Chloride ionsE. Methyl group

52. According to the State Pharmacopoeiaof Ukraine, phthalylsulfathiazole isquantitatively determined by means ofalkalimetry in non-aqueous medium. Thefollowing substance is used as a solvent inthis case:

A. Dimethyl formamideB. Anhydrous acetic acidC. Ethyl alcoholD. BenzeneE. Chloroform

53. A control laboratory needs to analyzestreptomycin powder for injections.According to the State Pharmacopoeia ofUkraine, to identify it sodium hydroxideis added into the dissolved powder, theresulting substance is heated, and theniron (III) chloride solution is added, whichresults in violet coloring of the substance.This test is known as:

A. Maltol testB. Ninhydrin testC. Vitali-Morin reactionD. Biuret testE. Thiochrome test

Фармакогнозiя 7

1. Vitali-Morin’s reaction is used toidentify tropane alkaloids in herbal rawmaterial. Name the alkaloid that can bedetected by means of this specific reaction:

A. ScopolamineB. CodeineC. MorphineD. PlatyphyllinE. Papaverine

2. What herbal bioactive substances yielda positive reaction with ferric ammoniumalum solution?

A. TanninsB. SaponinsC. PolysaccharidesD. BittersE. Fatty oils

3. Standard herbal material of lily-of-the-valley is obtained by drying it at atemperature of 50-60oC to prevent thefollowing possible biochemical process:

A. Enzymatic hydrolysis of cardiac glycosidesB. Oxidation of phenolic compoundsC. Volatilization of essential oilsD. Oxidation of resinsE. Oxidation of terpenoids

4. Proper harvesting of Frangula alnusherbal raw material greatly influences thequality and quantity of its active substances.Therefore the optimal time for buckthornbark harvesting is the period of:

A. Sap flowB. FruitingC. FloweringD. DefoliationE. Dormancy

5. Drugs derived from Rauvolfia serpentinaroots are used in hypertension treatment.Authenticity of Rauvolfia serpentina herbalraw material can be confirmed by its contentof:

A. ReserpineB. AtropineC. HyoscyamineD. VinblastineE. Adonitoxin

6. Medications Passit and Novopassit areused as tranquilizing, sedative and mildhypnotic agents. These medications areproduced from the following grass:

A. Purple passionflowerB. Three-lobe beggarticksC. Garden sageD. ElecampaneE. Lesser periwinkle

7. During microscopy of althaea root itis necessary to determine the presence ofstarch granules within the plant cells. Whatreagent enables such analysis?

A. Lugol’s solutionB. Ammonium hydroxideC. Concentrated sulfuric acidD. Alcohol solution of α-naphtholE. Thymol solution

8. Preparations of sorrel roots can have botha laxative and astringent effect. This is dueto the presence of the following biologicallyactive substances:

A. Anthracene derivatives and tanninsB. Flavonoids and essential oilsC. Essential and fatty oilsD. Coumarins and phenol glycosidesE. Iridoids and vitamins

9. Motherwort grass is a component ofhypotensive and sedative drugs. This herbalraw material should be harvested taking intoaccount its renewal rate. Therefore it can beharvested:

A. Once every 5 yearsB. Once every 2 yearsC. Once every 3 yearsD. Once every 10 yearsE. Every year

10. A certain type of herbal raw material isbeing harvested in spring during sap flow.Specify this material:

A. BarkB. FlowersC. BudsD. RootsE. Infructescences

11. To determine the quantity of wild-growing medicinal plants, it is necessary toknow their area of vegetation and yield perunit area. Yield of Thymus serpyllum grasscan be determined by the following method:

A. Projective cover methodB. Permanent quadrate methodC. VisuallyD. Model sample methodE. Geodesically

12. Codeine is used as a cough-depressant.What herbal raw material contains thisalkaloid?

A. Pods of opium poppyB. Grass of plume poppyC. Celandine grassD. Grass of common periwinkleE. Tea leaves

13. What herbal drug produced form


alkaloid-containing raw materials can berecommended for neurasthenia, insomnia,menopausal disorders?

A. NovopassitB. ErgotamineC. Glaucine hydrochlorideD. Securinine nitrateE. Vinblastine

14. A teenager with hyporexia has beenrecommended to drink medicinal herbaltea of the following composition: HerbaAbsinthii, Herba Millefolii. Specify thecharacteristic microscopic features ofArtemisia absinthium, which indicate itspresence in the herb mixture:

A. T-shaped hairs along the leaf edgeB. Simple and capitate hairsC. Branched, simple and ciliated hairsD. Retor-shaped hairsE. Branched and capitate hairs

15. Representatives of the family Solanaceaeare widely used in medical practiceas alkaloid-containing plants. Whichrepresentative is the source for productionof semi-synthetic steroid hormones?

A. Solanum laciniatumB. Atropa belladonnaC. Datura StramoniumD. Hyoscyamus nigerE. Solanum tuberosum

16. Birch buds are used as a diuretic. Qualityof the herbal raw material is determined byits content of:

A. Essential oilB. VitaminsC. LipidsD. IridoidsE. Saponins

17. Standardization of a certain herbal rawmaterial is done by calculating its alkaloidcontent in terms of hyoscyamine. Name thisherbal raw material:

A. Folia BelladonnaeB. Radices BerberidisC. Herba ChelidoniiD. Herba Thermopsidis lanceolataeE. Fructus Capsici

18. Valerian roots and rhizomes areprocessed in the phytochemistry workshopto produce tinctures and thick extracts thatare the components of combined sedatives.Name the group of bioactive compoundsthat includes valerian valepotriates, -valtrate, acevaltrate, and dihydrovaltrate:

A. IridoidsB. Essential oilsC. AlkaloidsD. PolysaccharidesE. Saponins

19. Specialists of a pharmaceuticalenterprice confirm the identity of Cassiaacutifolia herbal raw material. Duringreaction with alkali it developed cherry-redcoloring. What substances were identified?

A. AnthraquinonesB. TanninsC. AlkaloidsD. GlycosidesE. Iridoids

20. Menthol has anesthetic and antisepticeffect. What plant is the source of menthol?

A. Folia Menthae piperitaeB. Folia Uvae ursiC. Folia EucalyptiD. Folia SalviaeE. Folia Absinthii

21. The thyme grass is used for theproduction of herbal medical products forthe treatment of respiratory tract infections.Under the State Pharmacopoeia of Ukrainethe herbal raw material is subject tochromatographic identification by means ofthin layer chromatography. What substancesare detected on the chromatographic plateafter its treatment with due reagent?

A. Thymol and carvacrolB. Atropine and hyoscyamineC. Quercetin and rutinD. Apigenin and luteolinE. Arbutin and methyl arbutin

22. Yarrow grass is a component of herbalgastrointestinal remedies and is used tomake herbal drugs. According to the StatePharmacopoeia of Ukraine the quality ofthis herbal raw material is assessed by itscontent of:

A. Essential oils and proazulenesB. AlkaloidsC. PolysaccharidesD. Cardiac glycosidesE. Vitamines

23. Snake venom-based drugs are widelyapplied in treatment of locomotor apparatusdiseases. Main components of these venomsare:

A. Toxic proteinsB. AlkaloidsC. Cardiac glycosidesD. GlucosinolatesE. Phenol-alcohols


24. The cholagogue derived from Rosacanina fruit is used in treatment of liver andgallbladder diseases. Name this drug:

A. CholosasB. ChophytolC. PhytolytD. AllocholE. Altan

25. A medicinal plant contains hydroxycoumarinsand is used in production of venotonicagents. Name the herbal raw materialharvested from this plant:

A. Semina HippocastaniB. Herba MelilotiC. Fructus Ammi majorisD. Fructus Pastinacae sativaeE. Fructus Dauci carotae

26. Senna (cassia) foliage containsanthracene derivatives. Their presence canbe confirmed by qualitative reaction with:

A. AlkaliB. Molisch’s reagentC. Iron ammonium alumD. Iron (II) sulfateE. Fehling’s reagent

27. Digoxin is given to the patients withchronic heart failure. What medicinal plantthat contains cardiac glycoside is a source ofthis medicinal substance?

A. Digitalis lanataB. Erysimum canescensC. Strophanthus kombeD. Adonis vernalisE. Convallaria majalis

28. Vinblastine and Vincristine demonstrateantitumor activity. Name the herbal rawmaterial used in production of thesemedicines:

A. Folia Catharanthi roseiB. Herba Vincae minorisC. Rhizomata Nupharis luteiD. Folia BerberidisE. Herba Selaginis

29. A pharmaceutical warehouse received aherbal raw material that consists of ”cones”with loose scales that are attached to a firmtwig with or without fruits. Its collectivefruits are pale green, fragrant, and bitter.Name the plant from which this herbal rawmaterial was harvested:

A. Humulus lupulusB. Alnus incanaC. Juniperus communisD. Rubus idaeusE. Olea europeaea

30. Essential oil of a certain plant containsup to 80% of cineole. Specify the herbal rawmaterial that is collected from this plant:

A. Folia EucalyptiB. Folia BetulaeC. Folia Menthae piperitaeD. Folia МelissaeE. Folia Absinthii

31. To identify cardiac glycosides there areusually three groups of color reactions beingperformed: for steroid nucleus, for lactonicring, and for carbohydrate component.Specify the reaction for identification ofbutenolide ring:

A. Legal’s testB. Stahl’s reactionC. Mayer’s testD. Reaction of sublimationE. Dragendorff’s test

32. What fatty oil is nondrying due to itsoleic acid glyceride content?

A. Ricini oleumB. Helianthi oleumC. Maydis oleumD. Cucurbitae oleumE. Lini oleum

33. Several species of Polygonum genus areused in medicine. One of these species hasrootstocks rich in tanning agents, which areused to treat diarrrhea. Name this species:

A. Polygonum bistortaB. Polygonum hydropiperC. Polygonum persicariaD. Polygonum aviculareE. Polygonum alpinum

34. Hyoscyamine and scopolamine aretypically contained in the plants of thefollowing family:

A. SolanaceaeB. AsteraceaeC. PapaveraceaeD. ApocynaceaeE. Fabaceae

35. Spectrophotometric analysis ofanthracene derivatives contained inbuckthorn bark is based on the followingreaction:

A. Production of phenolates with alkali-ammonia solutionB. Oxidation of anthracene derivativesC. Anthraquinone reductionD. Salt precipitationE. Sublimation

36. A certain herbal raw material is usedto make Flamin cholagogue. Name this


material:

A. Helichrysi arenarii floresB. Meliloti herbaC. Violae herbaD. Tanaceti floresE. Cratаegi flores

37. In the process of phytochemicalexamination of buckthorn bark, the reactionwith alkaline solution resulted in redcoloring, which indicates the presence of thefollowing:

A. Anthracene derivativesB. SaponinsC. AlkaloidsD. FlavonoidsE. Slime

38. Atropa belladonna grass extract is acomponent of compound antispasmodicdrugs. Select such drug from the list:

A. BellasthesinB. OlimetinumC. SolutanD. UrolesanE. Herbogastrine

39. A pharmaceutical warehouse hasreceived a batch of herbal raw material- hawthorn flowers. Merchandise analysisrevealed in one of the sacks significantamount of bird-cherry flowers besides thehawthorn. What quality assessment of theherbal raw material should be performed?

A. Acceptable admixturesB. Mineral admixturesC. Moisture contentD. Ash values (Total ash)E. Extractive values

40. Buckthorn bark and its derivative drugs

are used as laxatives in medicine. Accordingto the State Pharmacopoeia of Ukraine,during chromatographic identification ofbuckthorn bark it is necessary to detect:

A. GlucofrangulinsB. PanaxosidesC. LanatosidesD. GinkgosidesE. Purpurea glycosides

41. Helichrysum arenarium herbal rawmaterial has anti-inflammatory andcholeretic effect. What parts of this plantare harvested?

A. FlowersB. GrassC. RhizomesD. FruitsE. Roots

42. A substance was received for analysis.The substance is a round seed 1-1,8 mmin diameter, yellow with bluish tint. Whenmashed with water, emits characteristicirritant odor; is sharp and acrid to taste. Theraw material can be identified as:

A. Mustard seedsB. Flax seedsC. Plantago psyllium seedsD. Fenugreek seedsE. Nigella seeds

43. What effect will anthracene derivativeshave, if -OH- groups are located in bothbenzene rings of anthraquinone?

A. LaxativeB. DiureticC. LitholyticD. SedativeE. Choleretic

Аптечна технологiя лiкiв 11

1. To improve iodine solubility in thepurified water, iodine must be:

A. Dissolved in the saturated solution ofpotassium iodideB. Dissolved in the boiling waterC. Reduced to fine powderD. Dispersed with glycerineE. Comminuted with alcohol

2. A pharmacist prepares fat-basedsuppositories by pouring. Specify the typeof fatty vehicle in this case:

A. ButyrolB. Vaseline (petroleum jelly)C. Cocoa butterD. WaxE. Spermaceti

3. To prepare a suspension a medicinalsubstance should be triturated with a smallamount of liquid. Specify the optimalamount of liquid for trituration of 10 g ofzinc oxide according to the Deriagin’s rule:

A. 5 mlB. 10 mlC. 2 mlD. 1 mlE. 0,5 ml

4. A doctor has prescribed pessaries ofunspecified mass. What mass should bechosen when pessaries are being preparedin a pharmacy?

A. 4,0B. 3,0C. 1,5D. 0,5E. 6,0

5. A pharmacist has made an injectionsolution that contains a salt produced byreaction of a strong base with a weak acid.Specify the necessary stabilizer:

A. Sodium hydrochlorideB. Sodium sulfateC. Hydrochloric acidD. Ascorbic acidE. Cysteine

6. A pharmacist prepares an injectionsolution that must be stabilized with 0,1Mof hydrochloric acid solution. What solutionis to be prepared?

A. NovocaineB. Calcium chlorideC. Potassium chlorideD. HexamethylenetetramineE. Sodium benzoate

7. A pharmacist needs to prepare eyedropswith pilocarpine hydrochloride. Specify the

optimal isotonic agent in this case:

A. Sodium chlorideB. Sodium sulfateC. GlucoseD. Boric acidE. Sodium nitrite

8. A pharmacist has made a drug by theprescription:Rp.: Sol. Protargoli 0,31,0

D.S. For irrigation.Specify the optimal technology ofpreparation:

A. Grind protargol in the mortar withglycerine, add waterB. Dissolve glycerine in the water, addprotargolC. Dissolve protargol in the water, addglycerineD. Measure out protargol into the vial,dissolve it in the water, add glycerineE. Measure out subsequently glycerine,water, and protargol into the vial

9. The doctor prescribed a patient 100 ml ofthermopsis grass infusion. How much of thedry concentrate of thermopsis grass (1:1)should the pharmacist measure out for thispatient?

A. 0.25 gB. 0.5 gC. 0.3 gD. 0.2 gE. 0.1 g

10. A patient needs the pharmacy toprepare him a camphor ointment. Whatconcentration of camphor should be inthe ointment according to the regulatorydocuments?

A. 10%B. 20%C. 15%D. 5%E. 1%

11. Urethral suppositories are being madefor a patient. What parameters should bespecified by the doctor in the formulationfor the pharmacist to be able to calculate thenecessary amount of the vehicle correctly?

A. Diameter, length, and quantity of thesupositoriesB. Diameter and quantity of the supositoriesC. Length and quantity of the supositoriesD. Diameter and vehicle of the supositoriesE. Quantity and vehicle of the supositories

12. A pharmacy prepares 10% sodiumchloride injection solution. Whatsterilization would be optimal in this case?


A. Autoclave chamber with high-pressuresaturated steamB. Sterile filtration through membraneC. Gas sterilizationD. Dry-heat sterilizationE. Irradiation sterilization

13. Prior to making a sodium chlorideisotonic solution a pharmacist baked thepowder in a dry heat box. What substancesare removed by this operation?

A. Pyrogenic substancesB. Redox substancesC. SulfatesD. ChloridesE. Moisture

14. A pharmacy received an infusionformulation. What herbal raw material canbe used to make this dosage form?

A. Valerian roots with rhizomesB. Rhubarb rootsC. Oak barkD. Arrow-wood barkE. Buckthorn bark

15. A pharmacist has prepared an eyedropsvehicle. What method of sterilization shouldbe chosen in this case?

A. Dry heatB. Flowing steamC. PasteurizationD. Ultraviolet irradiationE. Membrane filtration

16. A pharmacist has prepared a drug by theprescription:Rp.: Olei Helianthi 7,4

Solutionis Ammonii caustici 2,5 mlАсidi oleinici 0,1M. D. S:. Ammoniac liniment. For infriction.

Specify the type of disperse system:

A. Liniment-emulsionB. Combined linimentC. Liniment-solutionD. Liniment-suspensionE. Extractive liniment

17. A pharmacist has prepared a drug by theprescription:Rp.: Streptocidi

Dermatoli ana 1,0LanoliniVaselini ana 5,0M.D.S.: Apply to the affected skin.

Specify the type of the disperse system:

A. Suspension ointmentB. Solution ointmentC. Hydrophilic ointmentD. Combined ointmentE. Extraction ointment

18. To stabilize the suspension a pharmacisthas used potassium soap. What substancedoes this suspension contain?

A. SulfurB. Phenyl salicylateC. MentholD. Basic bismuth nitrateE. Camphor

19. A pharmacist has prepared a compoundointment. What is the correct sequence ofits preparation?

A. Suspension - solution - emulsionB. Solution - emulsion - suspensionC. Emulsion - suspension - solutionD. Solution - suspension - emulsionE. Emulsion - solution - suspension

20. To prepare decoctions with the volumeof 1000-3000 ml, they should be infused in aboiling water bath for:

A. 40 minutesB. 25 minutesC. 30 minutesD. 45 minutesE. 15 minutes

21. What medicinal agents must bemanufactured in aseptic conditions followedby thermal sterilization with high-pressuresaturated steam?

A. Injection solutions with thermostablesubstancesB. Injection solutions with thermolabilesubstancesC. Concentrated solutions for burettesystemsD. Liquid ingestible antibioticsE. 2% collargol solution for infants

22. When preparing dermatologicalointments the following substance shouldbe introduced by suspending:

A. XeroformB. CamphorC. MentholD. Protargol (silver proteinate)E. Ephedrine hydrochloride

23. What is the function of anhydrouslanolin in the suppository mass used forsuppositories prepared via hand rolling?


A. PlasticizerB. SolventC. PreservativeD. SolubilizerE. Emollient

24. A paharmacist makes powders bygrinding one of the formulation componentswith ethyl alcohol. This technology istypically applied when working with thefollowing substance:

A. StreptocidB. StarchC. TalcumD. Zinc oxideE. Bolus alba

25. A pharmacist prepares suppositoriesby pouring. Name the coefficientfor substitution of fatty vehicle withglycerinated gelatin vehicle:

A. 1.21B. 1.20C. 1.31D. 1.11E. 1.25

26. What technology should be chosen by apharmacist to make a liquid dosage form, ifit contains calcium gluconate?

A. Dissolve it in hot solvent or heat it up tofull dissolutionB. First grind it into powder when it is dry orwith small amount of solvent addedC. Dissolve in the water free of redoxsubsatancesD. Add equal amount of sodium chlorideE. Dissolve in alkaline medium

27. A pharmacy received a prescription forcompound powders containing a coloringagent. Which of the powder componentsgiven below is a colouring agent?

A. Ethacridine lactate (Rivanol)B. CamphorC. SulfanilamideD. Bismuth nitrateE. Silver proteinate (Protargol)

28. Infuser apparatus is used by a pharmacyto prepare:

A. Infusions and decoctionsB. Infusion solutionsC. SuspensionsD. EmulsionsE. Ointments

29. Specify the fluid used to coat theforms for pouring of the suppositories withhydrophilic vehicles:

A. Vaseline (petroleum jelly)B. GlycerineC. Purified waterD. Glycerine-water solutionE. Dimethylsulfoxide

30. Standard stactometer divides 1 ml ofwater into:

A. 20 dropsB. 15 dropsC. 25 dropsD. 30 dropsE. 10 drops

31. To prepare eyedrops with antibiotic adispensing chemist has been using flowingsteam sterilization under 100oC for 30minutes. What antibiotic allows for suchsterilization?

A. Levomycetin (Chloramphenicol)B. Sodium benzylpenicillinC. Streptomycin sulfateD. BiomycinE. Erythromycin

32. A pharmacist prepares 180 ml of adonisgrass infusion. How much herbal rawmaterial should be taken to prepare thisinfusion?

A. 6.0B. 10.0C. 2.0D. 15.0E. 18.0

33. A pharmacy prepares a drug thatcontains a high-molecular compound withunlimited swelling ability. Name thismaterial:

A. PepsinB. MethylcelluloseC. GelatineD. StarchE. Protargol

34. A pharmacy has received a prescriptionfor colloid solution. Name this solution:

A. Collargol solutionB. Sodium chloride solutionC. Nonaqueous solutionD. 5% glucose solutionE. Burow’s solution

35. A pharmacy has received a formulationfor the solution with a substance thatmoderately expands in the cold water. Namethis substance:


A. GelatinB. GlucoseC. Calcium chlorideD. Sodium chlorideE. Protargol (Silver proteinate)

36. A pharmacist prepares an infusion inproportion 1:400. Specify the herbal rawmaterial used in this infusion:

A. Thermopsis grassB. Motherwort grassC. Oak barkD. Althaea rootsE. Camomile grass

37. A pharmacist prepares a chamomileflowers infusion. Specify the proportion ofraw material to infusion:

A. 1:10B. 1:30C. 1:50D. 1:400E. 1:20

38. 50 ml of injection solution has beenmade in a pharmacy. Specify the process ofsolution sterilization:

A. 120oC - 8 minutesB. 180oC - 30 minutesC. 160oC - 15 minutesD. 140oC - 12 minutesE. 110oC - 15 minutes

39. A pharmacist prepares 100 ml of glucosesolution. Specify the amount of Weibel’sstabilizer necessary in this case:

A. 5 mlB. 10 mlC. 15 mlD. 20 mlE. 2 ml

40. A pharmacist has dissolved a medicinalsubstance in the sterile purified water

to make an eye ointment. Specify thismedicinal substance:

A. Pilocarpine hydrochlorideB. XeroformC. MentholD. Basic bismuth nitrateE. Purified sulfur

41. A powder containing a substance withspecific weight has been prepared in apharmacy. Name this substance:

A. Basic bismuth nitrateB. SugarC. Bolus albaD. TalcumE. Sodium bicarbonate

42. Weibel’s liquid is necessary to stabilizethe solution of a certain substance. Namethis substance:

A. GlucoseB. NovocaineC. Potassium chlorideD. Sodium chlorideE. Magnesium sulfate

43. A powder with a hard to disintegratesubstance has been made in a pharmacy.Specify this substance:

A. CamphorB. Sodium chloridesC. Osarsolum (Acetarsol)D. TalcumE. Sugar

44. Choose the solvent necessary toprepare a concentrated solution of sodiumbicarbonate in the pharmacy:

A. Purified waterB. Peach-kernel oilC. ChloroformD. Vaseline (petroleum jelly)E. Ethanol

Заводська технологiя лiкiв 15

1. A pharmaceutical company producesa medicine under the brand name”Corglyconum”. What herbal raw materialis used in preparation of this drug?

A. Lily-of-the-valley grassB. Wormwood grassC. Dandelion rootsD. Plantain foliageE. Buckthorn bark

2. A factrory workshop producingsuspensions and emulsions is going todevelop the manufacture of new drugs. Whatmechanisms can be used for the ultrasoundprocessing of drugs?

A. Liquid whistle, magnetostrictive sourceB. Dismembrator, electrical impulseplasmolyzerC. Disintegrator, liquid whistleD. Rotor-pulsation apparatus, dismembratorE. Centrifugal mixer with rotating housing

3. A pharmaceutical factory produces tabletsof sodium chloride. What is the method oftheir poduction?

A. Direct compression without additionalsubstancesB. MouldingC. Direct compression with the addition ofexcipientsD. Wet granulation prior to compressionE. Dry granulation prior to compression

4. There are various groups of adjuvants usedin tablet production. What is the function ofexcipients?

A. To make pills of a certain weightB. To create necessary adhesive force betweenparticlesC. To improve disintegrationD. To improve the flowability of granularmaterialE. To improve the taste

5. Various types of dryers can be used forgranule dehumidification. Specify the type of”СП-30” dryer:

A. Fluidized bed dryerB. Freeze dryerC. Infrared dryerD. Silica gel dryerE. Forced air dryer

6. Ampoule workshop of a factory produces5% oil solution of tocopherol acetate forinjections. What method of filling theampoules is optimal in this case?

A. SyringeB. VacuumC. DevaporationD. Syringe and vacuumE. Syringe and devaporation

7. Production of tablets requires stage-to-stage quality control. What devices are usedto determine the particle size distribution(fraction) of granules?

A. Standard set of sievesB. Various vibrosievesC. FriabilatorsD. Laboratory identifiersE. Microscope

8. Among various types of tablet externallayers there are enterosoluble coatings.Where in the body are they dissolved?

A. IntestineB. StomachC. Oral cavityD. RectumE. Esophagus

9. Specify the control methods aimed atdetecting mechanical impurities in parenteralsolutions:

A. Visual opticalB. Limulus testC. AmperometricD. GravitationalE. NMR and UV-visible spectroscopy

10. What stage is the last in making injectionsolutions?

A. LabelingB. SterilizationC. FilteringD. Qualitative controlE. Quantitative control

11. Specify the indicator that measures thetotal contribution of various solutes to theosmotic pressure of the solution:

A. OsmolalityB. IsohydricityC. IsotonicityD. IsoviscosityE. Apyrogenicity

12. Dosage precision during tabletmaking mainly depends on the followingtechnological property of tablet mass:

A. FlowabilityB. Relative densityC. Compression ratioD. CompressibilityE. Lyophilic property

13. Quality of dried extracts is assessedaccording to several criteria. Specify the


highest acceptable amount of moisturein dried extracts according to the StatePharmacopoeia of Ukraine:

A. 5%B. 25%C. 20%D. 75%E. 95%

14. Tyndallization is used at a pharmaceuticalfactory as a sterilization method forthermolabile substances. Essentially thismethod consists of:

A. Triple heating of solution to 40-60oCwith 24-hour-long intervals in between forthermostatingB. Autoclaving at 119-121oC with pressure at1.0-1.1 atmC. Sterilization with flowing steam at 100oCD. Sterilization with dry heat at 180-200oC fora lengthy period of timeE. Sterilization with high-frequency andmicrowave frequency current

15. When an extractant is filtered through aherbal raw material to obtain an extract ofthe substances soluble in this extractant, thisprocess is called:

A. PercolationB. MacerationC. RemacerationD. Turbo extractionE. Steeping

16. Phytochemical workshop of a factorymanufactures pancreatin. What is the sourcematerial for obtaining pancreatin?

A. Pancreas of pigs or cattleB. Gastric mucosa of pigsC. Lungs of cattleD. Heart of cattleE. Egg white

17. The following substance is used as anextractant in production of liquid extracts:

A. EthanolB. AcetoneC. DichloroethaneD. ChloroformE. Glycerine

18. Propellants are used in aerosolsproduction. Specify the function ofpropellants:

A. Create pressure in the packageB. Action prolongationC. StabilizationD. EmulsificationE. Dispersion

19. What factors affect tablet disintegration?

A. Amount and nature of disintegratingagentsB. Poor flowabilityC. High specific gravity of powdersD. Tablet powder contains lamellar crystalsE. Heterogeneity of granulated material

20. A pharmaceutical company producesessential oils via a method that consists ofessential oil transfer into gas phase followedby its absorption with fats and then itsextraction with alcohol. Name this method:

A. EnfleurageB. CompressionC. ExtractionD. HydrodistillationE. Dynamic sorption

21. A pharmaceutical company producesbelladonna tincture. In the process ofstandardization, excessive content of activesubstances was detected. How can thissituation be remedied?

A. Dilute the tincture with extractant tonormal concentrationB. Precipitate excessive active substancesC. Filter the tincture through adsorbentD. The tincture is a non-recoverable rejectmaterialE. This kind of deviation is not important

22. The phytochemical workshop of a factoryproduces liquid extracts. What extractantsare used in this manufacturing process?

A. Aqueous-alcoholic solutionsB. ChloroformC. Ammonia solutionD. DichloroethaneE. Water

23. A pharmaceutical company producestablets. Tabletting by means of directcompression requires:

A. No prior granulationB. Prior granulationC. Formation of massesD. Prior homogenizationE. Application of hydraulic press

24. A pharmaceutical company producessuppositories made from thermolabilemedicinal substances. What method is usedin their production?

A. PressingB. SteepingC. PouringD. RollingE. Dispersion

25. A pharmaceutical company producesliquid dosage forms. What principle is usedin rotary pulsation apparatus to obtain anemulsion?


A. Mechanical dispersionB. Ultrasonic dispersionC. SolubilizationD. CoacervationE. Maceration

26. A pharmaceutical company producesaromatic waters. Peppermint water shouldbe prepared in the following proportion:

A. 1:1000B. 1:2000C. 1:4000D. 1:10E. 1:1

27. A pharmaceutical company producessoft dosage forms. What indicator should bemeasured additionally for the soft dosageforms that are intended for application onheavily damaged skin?

A. SterilityB. pHC. IdentificationD. Microbiological purityE. Quantitative determination

28. A pharmaceutical company produceswarious medicines. Name the dosage formconsisting of separate hard dry particlesdisintegrated to varying degree:

A. PowdersB. TabletsC. SuspensionsD. EmulsionsE. Dried extract

29. Core tablets that are to be made intodragees must not have a flat shape. Why suchrequirement is necessary?

A. To prevent them from adhesion to eachotherB. They are not durable enoughC. To avoid prolonged contact with overlayingsuspensionD. To improve their appearanceE. To speed up the process of applying thecoating

30. Specify the formula of extractantcalculation in the process of creating atincture:

A. V = Vtincture + mrawmaterial ·KalcoholabsorptionB. mrawmaterial = mendproduct + mlosses

C. E = mlossesmrawmaterial

· 100%D. µ = mendproduct

mrawmaterial· 100%

E. V = Vtincture · n + mrawmaterial ·Kalcoholabsorption

31. Name the optimal vehicle for solublevaginal suppositories:

A. Polyethylene oxideB. Cocoa butterC. GlycerineD. FatE. Hard fat

32. What tablet coating protects stomachfrom harmful influence of active ingredients?

A. Intestinally absorbedB. Water-solubleC. Gastrically absorbedD. Fat-solubleE. -

33. In the process of industrial productionof rectal suppositories, certain substancesinsoluble both in water and suppositoryvehicle are introduced into this dosage form.Specify the optimal way to introduce thesesubstances:

A. Introduce the substances as a suspensionB. Introduce the substances as an emulsionC. Dissolve the substances in the water heatedto 45oCD. Melt a part of fatty vehicle and dissolve thesubstances thereE. Melt all of fatty vehicle and dissolve thesubstances there

34. In the process of industrial production,certain adjuvants are included in the softdosage forms as pH regulators. Name theseadjuvants:

A. Citric acid, sodium phosphate saltsB. Paraffin, spermacetiC. Glycerine, dimethyl sulfoxideD. Sodium lauryl sulfate, tween emulsifiersE. Benzalkonium chloride, benzyl alcohol

35. Polyethylene oxide base belongs to thefollowing group:

A. HydrophilicB. HydrophobicC. AmphiphilicD. EmulsionE. Fat

36. During storage, suspension instabilitymanifests itself as:

A. Sedimentation of particlesB. Flocculation of particlesC. Dissolution of particlesD. Caking of particlesE. Change of particles shape

Органiзацiя та економiка фармацiї 18

1. A pharmacy prepares drugs byindividual prescriptions. How often shouldthe floors be mopped down in theprescription department?

A. Once in a shiftB. Once in a weekC. Once every 10 daysD. Once every 5 daysE. Once every 3 days

2. Schedule of sanitation actions inpharmacies is regulated by the relevantregulatory acts. Cleaning day at a pharmacymust be scheduled at least once:

A. In a monthB. In a weekC. In 3 daysD. In 10 daysE. In 5 days

3. Which of the pharmacy departments isresponsible for checking the quantity andquality of received goods, their storage anddispensing to other departments?

A. Inventory departmentB. Compounding and production departmentC. Department of finished dosage formsD. Department of over-the-counter drugsE. Department of curative cosmetics

4. A pharmacy opens a bank account tostore funds and conduct ongoing businesstransactions. What kind of account should beopened?

A. CurrentB. ProvisionalC. DepositD. Letter of creditE. Investment

5. Natural persons registered as smallbusiness entities with simplified taxationscheme are subject to limitation of theannual amount of sales proceeds. Specify theproceeds limit:

A. 500 000 UAHB. 750 000 UAHC. 100 000 UAHD. 3 000 000 UAHE. 5 000 000 UAH

6. What final document is used forthe preparation of the report on thediscrepancies revealed in the course ofinventory at the pharmacy?

A. Act on the inventory resultsB. Inventory item descriptionC. ChecklistD. Commercial reportE. Invoice

7. What pharmacotherapeutic characteristic

of a medicine allows its classification as over-the-counter drug?

A. Medicine can cause no direct or indirectharm to the patient’s healthB. Medicine is available only for in-patienttreatmentC. Medicine contains substances that requireadditional research into their activity andside-effectsD. Medicine is available only by prescriptionE. Medicine has entered the pharmaceuticalmarket only resently and actual experiencewith its practical application is limited

8. Who is responsible for the acceptanceof goods and medical products withaccompanying incoming quality control?

A. Authorized representativeB. Supplier pharmacistC. Dispensing chemistD. Pharmacy head managerE. Analyst

9. A pharmacy receives centralized deliveriesof goods from the warehouse. Specify thedocument that is NOT NECESSARY foraccounting of goods receipt by the pharmacy:

A. Cash receipt orderB. Goods report (Inventory change report)C. Goods received record book by groups ofgoodsD. Goods received record book by item andsupplierE. Financial operating report of the pharmacy

10. An accountant conducts necessarycalculations for remuneration of labor. Namethe type of remuneration that is due for laborcarried out according to the work standardsand is paid within the amount determined bybasic or piece wages for factory workers andsalaries for office workers:

A. Basic payB. BonusC. IncrementD. One-off paymentE. Financial aid

11. A dispensing chemist with calculatedlength of service of 7 years has fallen ill.What percent of the sum stated in her sicklist would she receive?

A. 80%B. 100%C. 70%D. 60%E. 50%

12. Commercial and financial activity of apharmacy involves using returnable tare.Which of the following containers arereturned to the supplier?


A. Metal cylindersB. Packaging materialsC. Paper boxesD. Glass-stoppered bottlesE. Glassware

13. How often should a pharmacy make aninventory of its fixed assets?

A. Once a yearB. At least thrice a yearC. At least once in a quarterD. Once every three yearsE. At least twice a year

14. Limit cash balance is the maximumamount of monetary funds that can remainin the cash desk of an organization at the endof a workday. This limit is established by thefollowing authorities:

A. Pharmacy managementB. Chief physicianC. Local authoritiesD. Tax InspectorateE. -

15. Inspection of received medicines shouldbe performed by an authorized employee.What is NOT a part of the responsibilities ofthis person?

A. To draw up orders for medicines andmedical products, to conclude sales contractsB. To draw up conclusions regardinginspection of received medicinesC. To keep a record book of receivedmedicinesD. To check the pharmacy stock for low-quality or fake medicinesE. -

16. Doctor’s prescription fulfills severalfunctions. What function indicates thatthe doctor bears responsibility for correctprescription of medicines to the patient?

A. LegalB. SocialC. InformationalD. TechnologicalE. Economic

17. Pharmacy premises can be divided intoservice rooms and workrooms. Name theworkroom for storage of medical products:

A. Material storage roomB. Shop floorC. Washing roomD. Aseptic blockE. Distillation room

18. Accounting records are classified by thetype of asset accounting or by their sources.Active accounts keep record of the following:

A. Monetary fundsB. Equity capitalC. Bank loansD. Debt settlement with the creditorsE. Salaries payment

19. According to the rules in force,workrooms should regularly undergo humiddisinfection. How often should the floors bewashed?

A. No less than once in a shiftB. No less than twice in a weekC. No less than once in a weekD. No less than thrice in a weekE. No less than twice in a month

20. When servicing customers it is necessaryto maintain cash desk discipline. A cashiershould make records in the cash book:

A. Immediately after the cash transactionoccurredB. MonthlyC. QuarterlyD. WeeklyE. At the end of a workday

21. What department of a wholesale firmis tasked with search for and analysis ofpotential suppliers’ commercial offers, aswell as concluding supply contracts andsupervision of contract fulfillment?

A. Supply departmentB. Marketing departmentC. Shipping departmentD. Stores developmentE. Finance department

22. The Income Statement of a pharmacyfor the first quarter of 20XX contains thefollowing entries: goods turnover - 45 000UAH, production cost of products sold - 30000 UAH, turnover costs - 10 000 UAH.Determine the income:

A. 5 000 UAHB. 30 000 UAHC. 40 000 UAHD. 15 000 UAHE. 35 000 UAH

23. Under the current legislation, full orpartial exemption of persons and legalentities from tax payment is called:

A. Tax concessionB. Tax rateC. TaxD. Tax systemE. Subject to taxation

24. Name the official document on auditresults, which is drawn under the standardprocedure and contains conclusions aboutreporting credibillity and integrity offinancial statements of an organization:


A. Auditor’s conclusionB. Income statementC. Balance sheetD. Cash flow statementE. Statement of changes in equity

25. In Ukraine the auditor position eligibilityrequires the candidate to be a Ukrainiancitizen and have the qualification certificatefor work as an auditor within the Ukraine’sterritory. The certificate is effective for:

A. 5 yearsB. 3 yearsC. 2 yearsD. 1 yearsE. Indefinitely

26. The Dobropharma pharmacy managermakes plans for standard stock of variousgroups of goods, based on their purpose.Convenience goods belong to the followinggroup:

A. Current demandB. Specific demandC. Prior deliveryD. Seasonal accumulationE. Single delivery

27. Accounts receivable develop in theprocess of pharmaceutical company work.Specify where in the balance book they arerecorded:

A. AssetsB. LiabilitiesC. DebitD. CreditE. Account

28. Doctor’s prescription has severalfunctions. What function of the prescriptionallows its participation in the process ofpayment in cases when medicines should beissued free of charge or at a reduced price?

A. EconomicB. SocialC. LegalD. MedicalE. Technological

29. To ensure the quality of medicines thepharmacy devotes much attention to qualitycontrol. The following document is thequality assurance of a drug:

A. Quality certificateB. Registration certificateC. Certificate of compliance with hygieneregulationsD. Sanitary-epidemiological certificateE. Sanitary passport

30. How long should a retail businessthat deals in medicines keep the quality

certificates issued by drug manufacturers?

A. 3 yearsB. 1 yearC. 2 yearsD. 6 monthsE. 5 years

31. Pharmacy employees receive their salarypayments twice a month. What should thecashier do, if a pay day coincides with aholiday?

A. To pay the salaries one day earlierB. To pay the salaries after the holidayC. To pay the salaries on the holidayD. To pay the salaries 10 days earlierE. There are no regulations regardingpayment of salaries in this case

32. An important indicator of businessactivity is profitability of a business. Specifythe indices that can be used to measure theprofitability:

A. Profit/turnoverB. Turnover/cost priceC. Turnover/incomeD. Income/turnoverE. Liquidity/solvency

33. Difference between the retail price ofproducts sold and the margin determines:

A. Production costB. MarkupC. MarginD. IncomeE. Breakeven

34. An accountable person has received asum of money from the pharmacy cash deskto buy a calculator. What document recordsthe cash flow in such a transaction?

A. Cash expense orderB. Cash income orderC. InvoiceD. ReceiptE. Remains unregistered documentarily

35. Where on the shop floor of a pharmacyshould various nutritional supplements andhealth food be placed?

A. On separate shelves and in separateshopwindowsB. By their pharmacotherapy groupC. By their applicationD. Alongside medicinesE. By their Anatomical Therapeutic ChemicalClassification

36. A pharmacy provides certain categoriesof ill persons with medicines free of chargeor at a reduced price. What conditions allowfree of charge supply of out-patients withnecessary medicines?


A. Diabetes mellitusB. HeadacheC. ColdD. Muscle painE. Cuts and abrasions

37. Medicinal dyes should be stored in aspecial cabinet. Which of the listed medicalproducts is a dye:

A. Brilliant greenB. Hydrogen peroxideC. Ethyl alcoholD. GlucoseE. Ascorbic acid

38. To replenish its fixed assets, the pharmacymade a decision to arrange a credit withthe trading bank. What document must beconcluded in writing between the creditorand the debtor in this case?

A. Credit contractB. Full material liability contractC. LicenseD. Balance sheetE. Auditor’s conclusion

39. A pharmacy supplies the surgical wardof a hospital. What document enables thedispensing chemist to supply the goods:

A. Purchase orderB. Product revaluation noticeC. Report on the movement of packagingD. Consolidated registerE. Receipt log book

40. According to the law regulating labourremuneration, the businesses must establishtheir compensation plan in the followingdocument:

A. Collective agreementB. Contract of deliveryC. DecreeD. StatementE. Job description

41. Under the current legislation there isa certain list of controlled substances thatrequire keeping of the special inventory log.Select the drug that belongs on this list:

A. PhenobarbitalB. NovocaineC. SolpadeineD. DigoxinE. Analgin (Metamizole)

42. Bank is a financial mediator inpharmacy’s payments. Payment of taxeswithheld from the employees’ salary into thebudget requires the following document:

A. Payment orderB. Check payable in accountC. Accounting formD. Cash register receiptE. Cash order

43. A system of indicators characterizesfinancial and businesss activity of anorganization and the state of its assets andsources on the certain day in the monetaryunit. Name this system:

A. Balance sheetB. Business transactions log bookC. Double entryD. Turnover balance sheetE. Receipts and expenditures report

44. According to the current Ukrainianlegislation all drugs are divided into twocategories: prescription and nonprescription(over-the-counter). Which one of the listeddrugs requires no prescription?

A. Ascorbic acid, 500 mg №30B. Tramadol, capsules, 0,05 №10C. Clonidine, ampoules, 1 ml of 0,01%solution №10D. Phenobarbital, tablets, 100 mg №6E. Ketamine, 5% infusion solution, 2 ml №10

Менеджмент та маркетинг у фармацiї 22

1. A pharmaceutical company focuses onselling a diverse range of products coveringdifferent customer groups and regions. Whatkind of organizational structure is typical forsuch company?

A. DivisionalB. BureaucraticC. FunctionalD. CentralizedE. Decentralized

2. A pharmacist has a labour dispute with thepharmacy administration about reschedulinghis annual vacation leave. The employee canappeal against the decision of the pharmacyadministration to the following body:

A. Labour disputes committee (LDC)B. Trade union committeeC. Highest management bodies ofpharmaceutical service at the regional levelD. The Ministry of Public Health of UkraineE. Commercial court

3. What concept can be described as ”. . . anarea of exchange with its characteristicsystem of economic relations between goodsmanufacturers and consumers”?

A. MarketB. MarketingC. SalesD. AgreementE. Management

4. Collective labour agreement is concludedby a trade union committee with the businessowner on behalf of the workforce. Anycollective agreement is worked out in writtenform. Which article of the Labour Coderegulates the duration of the collectiveagreement?

A. 17B. 36C. 38D. 40E. 41

5. A set of values, traditions, behavioralnorms, and views inherent to an organisationcharacterizes its following feature:

A. CultureB. SuccessC. ProfitabilityD. Capitalization levelE. Self-development capability

6. For better coverage of various marketsthe ”Lubnyfarm” company sells a portionof its production through its own chain ofpharmacies, another portion is being soldthrough distributors, and the third - throughpharmacies of another business owners. Whatmarketing system of distribution is applied bythis company?

A. MultichannelB. HorizontalC. CorporateD. ContractualE. Administered

7. One of the most important marketcharacteristics is a goods economic trend.What economic trend can be characterized byrelative stability of high prices and the highestactivity of manufacturers and customers?

A. High (stable)B. SubsidingC. DownwardD. SluggishE. Low

8. The market can be characterized by thefollowing conditions: there are many sellersand buyers, who have no influence overcurrent prices; similar and interchangeablecompeting goods are available; there are noprice limits. What type of market is it?

A. Pure competitionB. Monopolistic competitionC. OligopolyD. Pure monopolyE. Economic planning

9. Manufacturer’s marketing departmentdetected negative demand for a certain goods.What would be the marketing task? Whattype of marketing should be applied?

A. Demand making, conversion marketingB. Demand leveling, synchromarketingC. Demand increase, remarketingD. Demand decrease, demarketingE. Demand stimulation, promotionalmarketing

10. Highly convincing approach to informingthe population about the company and itsproducts, commercial promotion of high usevalue of the goods and proper conduct ofbusiness by the company, actions intended toprompt purchase of goods by both active andpotential customers are all characteristic of:

A. AdverticementB. TrademarkC. MarketingD. CommunicationsE. Supply

11. A process dealing with drawing thedocuments, their processing, circulation andstorage is called records management. If alldocuments circulate through one organisationcenter, - office desk, - then such system ofrecords management is called:


A. CentralizedB. DecentralizedC. MixedD. ReferentE. Specialized

12. A pharmaceutical manufacturer sets theprice for a drug basing on its prime cost withpremium. What model of pricing is it?

A. Cost-basedB. CompetitiveC. Demand-basedD. Supply-basedE. Breakeven

13. Lately the ”Phytopharm” pharmaceuticalcompany has been forced to decrease itsproduction volume and range of goods.Not only does the company head managerdemonstrate no managerial abilities, but healso appears to be completely disinterested inthe running of the business and executes nocontrol over it. Determine the leadership typeof the head manager in this case:

A. LiberalB. DemocraticC. DirectiveD. AuthoritarianE. Autocratic

14. The ”Medpharm” wholesale pharmaceuticalfirm employs a system that encourages itsmanagers to achieve better results in salesby assigning them points for surpassingtheir sale goals. The points then becomeconverted into material remuneration. Thisway the company management carries out thefollowing management function:

A. MotivationB. OrganizationC. ControlD. DelegationE. Planning

15. To retain full control over its tradeoperations on the regional market, the”Fitoprom” pharmaceutical companyconducts its marketing policy without anyintermediate parties. Name the marketingpractice that excludes the middleman:

A. DirectB. CombinedC. MixedD. MediatedE. Indirect

16. A certain management style can becharacterized by the following features: theauthority is highly centralized; work duties ofthe employees are very structured; the abilityof employees to make decisions is extremelylimited; strict compliance with numerousrules and regulations is prioritized. Name thismanagement style:

A. AuthoritarianB. DemocraticC. CollectiveD. LiberalE. Direct

17. Number of mediators that pharmaceuticalgoods pass on their way from manufacturer toconsumer is called:

A. Length of distribution channelB. Level of distribution channelC. Width of distribution channelD. Volume of distribution channelE. -

18. To increase its sales, the ”Have a goodday!” pharmacy introduced a discount system.According to this system if a customerbuys 100 UAH worth of medical products,this customer receives 2% discount. Whatmarketing communication has this pharmacyimplemented?

A. Consumer-oriented sales promotionB. Middlemen-oriented sales promotionC. Personal saleD. Public relations, sponsorshipE. Salesmen-oriented sales promotion

19. A pharmacy offers to its customers achance to measure their blood pressure. Whattype of goods is it?

A. ServiceB. Convenience goodsC. Nondurable goodsD. Specialty goodsE. Unsought goods

20. Several independent mediators work inresale of medical equipment. What group ofmediators includes persons and legal entitiesthat specialize in sales of durable goods thatrequire considerabe after-sales service?

A. DealerB. BrokerC. Commission agentD. ConsigneeE. Agent

21. A pharmaceutical company has divided itscustomers into groups based on their gender,age, and size of their families. What approachto market segmentation is the basis of thiscustomer division?

A. DemographicB. GeographicC. SocioeconomicD. PsychographicE. Behavioral

22. To decrease business risks, apharmaceutical company decided to expandits activity and penetrate into new market (toopen a fitness center). Name this process:


A. DiversificationB. IntensificationC. ConglomerationD. ModernizationE. Integration

23. Hierarchic structure of the Agapetuspharmacy management foresees thatauthority is being passed on directly from thepharmacy manager to the employees. Specifythis type of authority:

A. LineB. FunctionalC. Line and staffD. DivisionalE. Matrix

24. A pharmacist approached the chiefmanager of the pharmacy with a request forpay raise. The chief manager turned down thisrequest. What type of conflict is it?

A. Interpersonal conflictB. Intrapersonal conflictC. Dysfunctional conflictD. Intergroup conflictE. Conflict between individual and group

25. Product sales manager of a pharmaceuticalcompany was tasked with sales programinspection and given 10 days to completethis task. The manager completed this taskwithin 5 days and expects to be rewardedwith a bonus. What theory of achievementmotivation is based on expectation of acertain event?

A. Vroom’s expectancy theoryB. Maslow’s hierarchy of needsC. Herzberg’s two-factor theoryD. McClelland’s theory of needsE. McGregor’s Theory X and Theory Y

26. The management plans to open a newpharmacy in one of the local villages. Suchactivity can be identified as:

A. Growth strategyB. Vertical integrationC. Horizontal integrationD. Conglomerate diversificationE. Horizontal diversification

27. To minimize business risks, the boardof directors of a pharmaceutical companydecides to expand into a market of plantprotection products. Such approach to riskmanagement is called:

A. DiversificationB. InsuranceC. IntensificationD. IntegrationE. Consolidation

28. According to ecological survey, a certainpharmaceutical manufacturer holds the firstplace among the local ”green” industries.

What marketing concept is chosen by thismanufacturer in relations with its customers?

A. Socio-ethical marketingB. Product developmentC. Intensification of commercial effortD. Production developmentE. Integrated marketing

29. Publicly-owned ”Isotope” factory is theonly manufacturer of radiopharmaceuticalsin Ukraine. What type of distribution ischaracteristic of radioactive drugs?

A. ExclusiveB. SelectiveC. IntensiveD. SampleE. Bulk

30. A pharmaceutical company plans tointroduce traditional herbal remedies tonew markets. What marketing opportunityaccording to Ansoff Matrix was used by thecompany?

A. Market developmentB. Market penetrationC. Product developmentD. DiversificationE. Consolidation

31. Calendula Ointment is placed on the shelfnext to Dr. Theiss Calendula Ointment. Whatapproach to the shelf layout is used in thispharmacy?

A. Among competitorsB. Corporate block layoutC. By package sizeD. Doubling product facingsE. Seasonality

32. The chief manager of a pharmacydesigns its organizational structure andjob descriptions for its employees. Thesearrangements belong to the followingmanagement method:

A. OrganizationalB. EconomicC. LegalD. SimulationE. Psychosocial

33. Strategic planning of pharmaceuticalcompanies consists of several consecutivestages. What stage is the final one?

A. Strategy assessmentB. Setting goals and tasksC. Environment assessment and analysisD. Analysis of organisation’s internal strengthand weaknessesE. Choice of strategy

34. A pharmacist approached the chiefmanager of the pharmacy with a propositionto introduce an additional service for their


customers - blood pressure measurement.What type of communication is it?

A. Vertical ascendingB. Vertical descendingC. ExternalD. Intra-levelE. Horizontal

35. A manager of a wholesale pharmaceuticalcompany is responsible for relaying varioustasks to the employees and supervisesthe fulfillment of assigned tasks. Whatmanagement level corresponds with theseduties?

A. TechnicalB. AdministrativeC. InstitutionalD. Top-levelE. Middle-level

36. A ”Sunrise” pharmacy chain has changedthe placement of medical products on itsshelves and in the shop windows, to studywhat effect would this merchandising tacticshave on the sales amount. What method ofmarketing research was used by this pharmacychain?

A. ExperimentB. PanelC. SurveyD. ObservationE. -

37. A pharmaceutical company loweredits price for a certain drug due to strongcompetition and decreasing demand for thisdrug. What is the purpose of such pricepolicy?

A. To ensure business survivalB. To maximize profitsC. To create the image of high-quality medicinemanufacturerD. To gain leadership due to high quality ofmanufactured medicinesE. -

38. What activity of a pharmaceuticalcompany includes improvement ofemployees’ working and living conditions,healthcare and medical insurance and othermeans of social development?

A. Social responsibilityB. Commercial activityC. Financial activityD. Industrial activityE. Charity

39. What variable of the internal environmentof the ”Provisor” pharmacy can be describedas the ways of transformation of componentmaterials (medicinal agents "an gross") intoend product (various dosage forms)?

A. TechnologiesB. MissionC. TasksD. StructureE. Human resources

40. The documents of a pharmaceuticalcompany are being received and sent ina centralized manner; the documents arestored, drawn-up, registered, and assembledinto cases both in the Office Desk of thecompany and the company’s divisions. Specifythis type of records management system:

A. MixedB. CentralizedC. DecentralizedD. ReferentE. -

41. Employees of a wholesale pharmaceuticalcompany have undergone an assessment fortheir compliance with the requirements oftheir respective positions. Specify the type ofhuman resources assessment:

A. ConcludingB. PreliminaryC. ConcurrentD. FinancialE. -

42. In the process of pharmaceutical companyentering an offshore market the traditionsand customs, religion, system of values,and education level of the local populationwere analyzed. What factors of internationalmarketing environment were researched?

A. SocioculturalB. PoliticalC. EconomicD. LegalE. Technological

43. What means of demand stimulation can beapplied by pharmacy management among itsemployees?

A. BonusesB. In-store advertisingC. Layout of medical products in shop-windows and on shelvesD. CouponsE. -

Клiнiчна фармацiя 26

1. A patient suffering from bronchialasthma was diagnosed with essentialhypertension. What antihypertensive drugis contraindicated for this patient?

A. PropranololB. CaptoprilC. AmlodipineD. Hypothiazid (Hydrochlorothiazide)E. Verapamil

2. A pharmacy customer complains ofconstricting retrosternal pain that irradiatesinto the left arm; he fears that he may die.The pain appeared suddenly after physicalexertion. Name the first aid medicine in thiscase:

A. NitroglycerineB. MetacyclineC. Naphthyzin (Naphazoline)D. PananginE. Riboxin (Inosine)

3. To treat iron-deficiency anemia thefollowing drug is usually prescribed:

A. FerroplexB. Furagin (Furazidinum)C. CorticosteroidsD. HeparinE. Vicasol (Menadione)

4. A 45-year-old man has been takinglong-acting nitrates twice a day for a year.Currently a decrease in effectiveness of thepharmacotherapy is being observed. Whatside-effect can be suspected in the firstplace?

A. Development of nitrate toleranceB. Progressing ischemic heart diseaseC. Progressing coronary atherosclerosisD. Myocardial infarctionE. Impairment of coronary circulation

5. A 43-year-old patient was delivered toan admission room with renal colic attack.What group of drugs would be the mosteffective during the attack?

A. AntispasmodicsB. HepatoprotectorsC. AntacidsD. AntibioticsE. Cholagogues

6. A 63-year-old man suffering fromischemic heart disease was diagnosed withangle closure glaucoma. What group ofdrugs is CONTRAINDICATED in thiscase?

A. NitratesB. β-adrenergic blockersC. Calcium antagonistsD. AnticoagulantsE. Statins

7. What hypotensive drug is an agentof choice for the patients suffering fromarterial hypertension with concomitant typeI diabetes mellitus?

A. LisinoprilB. HydrochlorothiazideC. AtenololD. LabetalolE. Carvedilol

8. A 25-year-old man is diagnosed with acutepyelonephritis of moderate severity. Whatdrugs should be prescribed for etiotropictherapy?

A. Antimicrobial agentsB. GlucocorticoidsC. Nonsteroidal anti-inflammatory drugsD. Anticholinesterase drugsE. Antiarrhythmic drugs

9. A 53-year-old woman suffers fromischemic heart disease and angina pectoris.What drug can be used to stop anginapectoris attacks?

A. NitroglycerineB. Drotaverine hydrochlorideC. PropranololD. DipiridamolE. Acetylsalicylic acid

10. A patient is 20 years old. After shewas stung by a bee the patient developedQuincke’s disease; rash in the form ofblisters and papulae appeared on her torso.First aid in this case should start withadministering the following drug:

A. PrednisoloneB. PenicillinC. Fresh frozen plasmaD. Rheopolyglukin (Dextran)E. Haemodes

11. A patient developed dry cough whileundergoing pharmacotherapy for arterialhypertension. What group of drugs can becharacterized by this side effect?

A. ACE inhibitorsB. Calcium antagonistsC. AntipsychoticsD. TranquilizersE. Antacids

12. During an asphyxiating attack thepatient with bronchial asthma was givenintravenously a drug that caused nausea,headache, excitation, and palpitations as


side effects. What drug can cause suchreaction?

A. Euphylline (Aminophylline)B. PrednisoloneC. AmbroxolD. Suprastin (Chloropyramine)E. Papaverine hydrochloride

13. A man with gastric ulcer is prescribedanti-Helicobacter pylori therapy. On the 3rdday the patient developed black coloring offeces. What had caused such changes?

A. Bismuth subcitrateB. OmeprazoleC. MetronidazoleD. TetracyclineE. Tinidazole

14. A 46-year-old pharmacy customersuffers from chronic bronchitis and needs amedicine to facilitate expectoration of thickviscous sputum. What drug is indicated inthis case?

A. AmbroxolB. OxeladinC. SalbutamolD. ButamirateE. Codeine phosphate

15. A 52-year-old patient has beendiagnosed with gouty arthritis, phase 2.What drug should be basic in treatment ofthis patient?

A. AllopurinolB. HydrochlorothiazideC. ParacetamolD. FurosemideE. Penicillin

16. A 3-year-old child is intolerant toparacetamol. What antipyretic drug can betaken instead?

A. IbuprofenB. Acetylsalicylic acidC. NimesulideD. NaproxenE. Diclofenac sodium

17. A patient with angina pectoris takeslong-acting nitrates. Consult him what side-effect is the most common for these drugs:

A. HeadacheB. NauseaC. VomitingD. DiarrheaE. Constipation

18. A 60-year-old patient, who had suffereda myocardial infarction, was prescribedacetylsalicylic acid as an antiaggregant.Specify the optimal daily dosage of

acetylsalicylic acid for antiaggregatoryeffect:

A. 100 mgB. 200 mgC. 300 mgD. 400 mgE. 500 mg

19. Genetically induced adverse reaction toa certain drug is caused by various enzymedefects. Name this reaction:

A. IdiosyncrasyB. Withdrawal syndromeC. Steal syndromeD. Rebound effectE. Dysbiosis

20. A 25-year-old woman is in thethird trimester of her pregnancy. Duringher regular examination, US detecteda malformation in the fetus. Medicalhistory of the patient shows that she wastaking large doses of diazepam withoutprescription during her pregnancy. Whattype of side effect has occurred in this case?

A. TeratogenicB. EmbryotoxicC. FetotoxicD. CarcinogenicE. Mutagenic

21. A 43-year-old woman has come toa pharmacy with complaints of sharpheadache in the occipital area, palpitations,”visual snow” in her eyes, nausea; herBP is 180/110 mm Hg. These symptomscorrespond with:

A. Hypertensic crisisB. Migraine attackC. Exertional angina pectoris attackD. Cervical osteochondrosisE. Acute conjunctivitis

22. A patient, who has undergone treatmentfor community-acquired pneumonia,complains of hearing impairment. Whatantibacterial drug could result in such a side-effect?

A. GentamicinB. Amoxicillin/clavulanateC. CefazolinD. CiprofloxacinE. Clarithromycin

23. A 36-year-old woman with herpeticrash on her lips has come to a pharmacy.Recommend her a drug for topicaltreatment:


A. AcyclovirB. FluconazoleC. LevofloxacinD. MetronidazoleE. Amikacin

24. A woman with open tuberculosisis undergoing in-patient treatment inthe tuberculosis clinic. What drug wasprescribed by her physician for etiotropictreatment?

A. IsoniazidB. AcyclovirC. MetronidazoleD. Doxycycline hydrochlorideE. Benzylpenicillin (Penicillin G)

25. A patient has been receiving palliativetreatment with morphine hydrochloridefor a week. Following that the patientdemands continuation of this treatment.What phenomenon has occurred in thiscase?

A. DependenceB. ToleranceC. CumulationD. PotentiationE. Summation

26. A 65-year-old man with community-acquired pneumonia was prescribedantibiotic agent amikacin. It should be keptin mind, that amikacin has the followingside-effect:

A. OtotoxicityB. Red coloring of urineC. VomitingD. Increased blood pressureE. Decreased blood pressure

27. Several cholesterol gallstones aredetected in the gallbladder of a woman.Choose the drug to dissolve and excrete thestones:

A. Ursodeoxycholic acidB. PapaverineC. DomperidoneD. LoperamideE. Platyphyllin

28. During anti-Helicobacter quadrotherapypatient’s feces colored black. What drugcould have caused this effect?

A. Bismuth subcitrateB. OmeprazoleC. AmoxicillinD. ClarithromycinE. Metronidazole

29. A patient receives heparin for acutemyocardial infarction. On the third daythe patient developed hematuria and

subcutaneous hematomas. What medicineshould be prescribed as an antidote in thiscase?

A. Protamine sulfateB. Vicasol (Menadione)C. StreptokinaseD. ClopidogrelE. Acetylsalicylic acid

30. A young mother has come to a pharmacyto buy an antipyretic drug for her 3-month-old infant. What dosage form would youchoose for the infant?

A. SuppositoriesB. TabletsC. CapsulesD. SprayE. Lozenges

31. A 74-year-old man came to thepharmacy. He had been prescribedampicillin for antibiotic treatment ofdysenteric gastroenterocolitis. What groupof drugs should be recommended fordysbiosis prevention in this case?

A. ProbioticsB. AntacidsC. Enzymatic agentsD. SorbentsE. Immunosuppressants

32. A 28-year-old woman came to apharmacy complaining of constipation thatdeveloped after antacid treatment. Whatdrug could be the cause of this symptom?

A. Aluminium-containing drugsB. Magnesium-containing drugsC. Calcium carbonateD. SimethiconeE. Ranitidine

33. What antacid can cause constipations,osteoporosis, and encephalopathy whentaken for a long period of time?

A. Aluminium hydroxideB. Sodium bicarbonateC. Calcium carbonateD. Sodium alginateE. Magnesium oxide

34. A 60-year-old man has cometo a pharmacy with complaints ofimpaired twilight vision, dry sclera,cracked and peeling skin. The dispensingchemist suspected hypovitaminosis andrecommended the customer to take thefollowing drug after consultation with thephysician:


A. Retinol acetateB. Tocopherol acetateC. ErgocalciferolD. Vicasol (Menadione)E. Ascorbic acid

35. A patient with arterial hypertension,who takes captopril, was prescribed apotassium-sparing diuretic, spironolactone.What complication can develop in thepatient due to this combination of drugs?

A. HyperkalemiaB. HypocalcemiaC. HyponatremiaD. HypoglycemiaE. Hypernatremia

36. A patient was prescribed an oralantibiotic for treatment and an antacid toremove heartburn symptoms. If the drugsare taken simultaneously their interactioncan result in the following:

A. Antibiotic malabsorptionB. Relative overdosageC. Inhibition of hepatic microsomal enzymesD. Mutual potentiationE. Acceleration of metabolism and excretion

37. A 63-year-old woman suffering fromdiabetic nephropathy with functionaldisturbance of the kidneys needs etiotropictreatment for focal pneumonia. What drugis CONTRAINDICATED in this case?

A. AminoglycosidesB. Natural penicillinsC. Synthetic penicillinsD. MacrolidesE. Combined penicillins

38. A 68-year-old man has been prescribeda hypolipidemic agent as a part of hiscombination therapy for ischemic heartdisease. Name this drug:

A. AtorvastatinB. NitroglycerineC. LisinoprilD. NifedipineE. Hydrochlorothiazide

39. When dispensing an antacid agent andofloxacin in tablets, the dispensing chemistwarned the customer that these drugs

should be taken separately with 2-hourinterval in between. Simultaneous taking ofboth drugs:

A. Decreases ofloxacin absorptionB. Increases ofloxacin absorptionC. Increases antacid effectivenessD. Decreases antacid effectivenessE. Increases risk of dysbiosis

40. A 54-year-old hypertonic patientundergoing pharmacotherapy developedbronchial spasm. His physician considersit to be a therapy-induced complicationcaused by the drug that belongs to thefollowing group:

A. β-adrenergic blockersB. Calcium antagonistsC. α-adrenergic blockersD. Ganglionic blockersE. Diuretics

41. A patient with chronic heart failure,who has been taking cardiac glycosides,developed signs of glycoside intoxication.What antidote would be advisable in thiscase?

A. Unithiol (DMPS)B. Vicasol (Menadione)C. ProtamineD. NaloxoneE. Methionine

42. For treatment of enteric infection a 36-year-old woman was prescribed a nitrofuranderivative that is poorly absorbed in theintestine and takes its effect along theintestinal tract. Name this drug:

A. NifuroxazideB. Furacilin (Nitrofural)C. NitroxolineD. Furadonin (Nitrofurantoin)E. Nalidixic acid

43. Specify the drugs recommended forprevention and correction of dysbioticproblems caused by antibiotic therapy:

A. ProbioticsB. AntacidsC. ProkineticsD. UrosepticsE. Choleretics

Krok 2 · the substance of potassium acetate. What reagent conﬁrms the presence of potassium...

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