Kennisontwikkeling medische sector CuraçaoNov 04, 2015 · DCAA 051115 Red Cross Blood Bank...

Red Cross Blood Bank Foundation DCAA 051115

Kennisontwikkeling medische sector

Curaçao

Prof. dr. A.J. Duits

Red Cross Blood Bank Foundation Curaçao


Integrative personal omics profile (iPOP)

Cell 148, 1293–1307, March 16, 2012


• EVIDENCE BASED

• DATA DRIVEN


SCIENTIFIC PUBLICATION IN PEER

REVIEWED JOURNALS:

• PUBLICATION

* EXPOSURE WORLD WIDE

• PRESENTATIONS

• COLLABORATIONS


Quantum entanglement is a physical

phenomenon that occurs when pairs or

groups of particles are generated or

interact in ways such that the quantum

state of each particle cannot be

described independently—instead, a

quantum state may be given for the

system as a whole.

https://en.wikipedia.org/wiki/Particle

https://en.wikipedia.org/wiki/Quantum_state


RED CROSS BLOOD BANK FOUNDATION CURACAO


RESEARCH AREAS:

• RELEVANT FOR LOCAL SITUATION

• SUSTAINABLE

• COLLABORATIVE

• EDUCATIONAL


KNOWLEDGE MANAGEMENT:

• APPROPRIATE CADRES

* Legal

* Organizational

• ALLOCATED BUDGET

• INFRASTRUCTURE

• DEDICATED PERSONNEL

• STUDENTS

• STIMULATING ENVIRONMENT


STATUTEN STICHTING RODE KRUIS

BLOEDBANK


GLOBAL HEALTH: LOCAL PUBLIC HEALTH

• DISEASES

• MULTI-CULTURAL SOCIETY


RESEARCH AREAS:

• SUSTAINABLE BLOOD BANK SYSTEMS

• HIV

• INFECTIOUS DISEASES

• SICKLE CELL DISEASE

• MEDICAL EDUCATION


PROJECTS:

PhD programs:

- PhD students

- Master Medicine/Interns/Residents

Scientific method

International collaboration:

Shared challenges/shared

posibilities/“win-win”


SICKLE CELL DISEASE PROJECT

Slotervaart hospital

Academic Medical Centre

Amsterdam (AMC)


TOPICAL GM-CSF


HIV PROJECT

Prof. dr. Joep Lange


CHARACTERISTICS OF HIV INFECTED

POPULATION IN CURAÇAO


MMAATSCHAPPELIJK RELEVANT


"The HIV-1 Epidemic Amongst Men Having Sex

With Men in the Netherlands is Dispersed

Amongst a Large Number of Self-sustaining and

Persistent Transmission Clusters: A Combined

Mathematical and Phylogenetic Study on

Observational Data" (PMEDICINE-D-14-

01427R3)by Daniela Bezemer, Ph.D.; Anne Cori; Oliver Ratmann; Ard van

Sighem; Gonneke Hermanides; Bas E. Dutilh; Luuk Gras; Nuno

Rodrigues Faria; Rob van den Hengel; Ashley Duits; Peter Reiss; Frank

de Wolf; Christophe Fraser

Accepted for publication


INFECTIOUS DISEASE PROJECT


GP medical center/Surveillance center

INNOVATIVE EARLY WARNING SYSTEM

Dr. I. Gerstenbluth, Epidemiology and

Research Unit

23 November 2015

Epidemiology & Research Unit

Public Health Service Curaçao

Reports related to ongoing Chikungunya OutbreakSyndromic Surveillance System, Curaçao 2014 - 2015

0

25

50

75

100

125

150

175

200

225

250

1 4 7 10 13 16 19 22 25 28 31 34 37 40 43 46 49 52 2 5 8 11 14 17 20 23 26 29 32 35 38 41 44 47 50

0.00

0.10

0.20

0.30

0.40

0.50

0.60

0.70

0.80

0.90

1.00

undiff fever ≥ 5yrs undiff fever < 5yrs rash & fever fever & hemor fever & neuro participation 2014

First case of

CHIKV detected

in week 25


RED CROSS BLOOD BANK FOUNDATION

DONORS: 100% VOLUNTARY NON-REMUNERATED

BLOOD PRODUCTS: 100% LEUKOREDUCED

IDT: SEROLOGY (HIV, HCV, HTLV, SYPH, HBV)

NAT (HIV,HCV,HBV) WNV

QUALITY: GMP (EU/AABB)

SUSTAINABLE BLOOD BANK SYSTEMS

PROJECT


SUSTAINABLE SMALL SCALE

BLOOD BANKS

COMPLYING WITH EU QUALITY

NORMS


SCIENTIFIC PUBLICATION IN PEER

REVIEWED JOURNALS:

• PUBLICATION

* EXPOSURE WORLD WIDE

• PRESENTATIONS

• COLLABORATIONS


STRATEGIC PLAN 2015-2019


EMERGING INFECTIOUS DISEASES THREATS FOR TRANSFUSION

OF SAFE BLOOD

SUSTAINABLE BLOOD BANK SYSTEMS

PROJECT


TEST

AVAILABILITY


• Riboflavin and its photoproducts are naturally present in normalblood, no new compounds are formed

• Riboflavin and its photoproducts are non-toxic & non-mutagenic

• Extensive toxicology testing has shown no safety concerns

Mirasol does not require removalof riboflavin or its photo-products

No contra-indications for patients

No special precautions for staff

47

PN 306690-190 ©2009 CaridianBCT

Riboflavin (vitamin B2)Essential nutrient,

Recommended daily allowance 1.7 mgToxicology, Mutagenicity (GRAS, USA FDA)

Riboflavin: the ideal sensitizer

OH

OHOH

OH

CH3

CH3

O

ON

NHN

N

GRAS= Genreally Regardes As Safe

Mirasol System Process for Platelets and Plasma

Connect and transfer product to illumination

bag

Add riboflavin solution

Illuminate4 to10

minutes

Transfuse or store for up to five days

Pla

tele

ts

Connect and transfer product to

illumination bag

Add riboflavin solution

Illuminate 4 to10 minutes

Transfer to storage bag

Transfuse or store frozen

for up totwo yearsP

lasm

a

Same simple process for platelets and plasma

49


REFERRAL CENTER • TRAINING

• RESEARCH


• Residents

• Interns

• Nurses

• Medical

Specialists

• Medical

professionals

TEACHING HOSPITAL

UMCG AFFILIATE

MEDICAL EDUCATION PROJECT


• ENHANCE LOCAL

HEALTH CARE

QUALITY

• BETTER CULTURAL

COMPETENCE

DUTCH MEDICAL

DOCTOR


Reports that say that something hasn't happened are always

interesting to me, because as we know, there are known

knowns; there are things we know we know. We also know

there are known unknowns; that is to say we know there are

some things we do not know. But there are also unknown

unknowns – the ones we don't know we don't know. And if

one looks throughout the history of our country and other free

countries, it is the latter category that tend to be the difficult

ones.[1]


APPROACH


Big data is like teenage sex: everyone talks

about it, nobody really knows how to do it,

everyone thinks everyone else is doing it, so

everyone claims they are doing it.

Dan Ariely, Duke University


GENERATE DATA



LANGUAGE



UNIVERSAL SCALE



PEER REVIEW/PUBLICATION


GLOBAL HEALTH HAS BECOME LOCAL PUBLIC HEALTH:

• SHARED RESPONSIBILITY

• SHARED OPPORTUNITY

• SCIENTISTS/PROFESSIONALS/INSTITUTES

COLLABORATE

• GOVERNMENTS/EU SHOULD FURTHER FACILITATE

(IMPROVEMENT)


More than half of the 25 OCTs are located in

the Caribbean region

HIGH END CARIBBEAN GDP


Brussels, 20-10-2015


CURACAO BIOMEDICAL & HEALTH RESEARCH

FOUNDATION (CBHRI):

• Non profit

• Understanding, treating and preventing human

ailments

• Prevalence Caribbean and Latin America

DR. B. MARTINA

Kennisontwikkeling medische sector CuraçaoNov 04, 2015 · DCAA 051115 Red Cross Blood Bank...

Documents

Transcript of Kennisontwikkeling medische sector CuraçaoNov 04, 2015 · DCAA 051115 Red Cross Blood Bank...