Hepato-Nephrosis Syndrome in Broiler Chicks in Kathmandu Valley
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Transcript of Hepato-Nephrosis Syndrome in Broiler Chicks in Kathmandu Valley
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8/14/2019 Hepato-Nephrosis Syndrome in Broiler Chicks in Kathmandu Valley
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Hepato-NephrosisHepato-Nephrosissyndrome in Broilersyndrome in BroilerChicks in KathmanduChicks in Kathmandu
Valley :2009Valley :2009
Dr.Kedar KarkiDr.Kedar Karki
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Background During the first week of July 2009
there has been a sudden increase in
death of broiler chicken above oraround 5 week age with symptomslike hepato-
nephrosis,hydropericaedium,flipedover.
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Since the incidence of hepato-nephrosiswas noticed on farms using a particularfeed and that change of feed invariablyhelped to control the mortality rate within3- 5 days, the investigation were divertedto determine the Fungal spp.contents offeed.Major fungus spp. recovered from
different feed samples,and posr-mortemtissue samples were Penicillium, Aspergillussingly or together
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Feed quality problems due tocontamination with moulds andmycotoxins are believed to be theprimary cause of serious liver andkidney disease in broiler and layerchicks
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Hepato-nephrosis is responsible for aserious increase in mortality of broilerand layer chicks which has risen from 12to 30% and 6 to 10% respectively.
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Earlier during 1987 a similar situationwas created due to hydropericardium
syndrome in broilers which caused and isstill causing heavy mortality in youngchicks in Pakistan
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The incidence of hepato-nephrosis wasfirst seen during August 1996 with ahistory of sudden deaths withoutapparent morbidity.
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Postmortem lesions consisted ofenlargement of the liver with differentdegrees of discolouration and evenhaemorrhages.
The gall bladder was invariablydistended with pale yellowish green bile
water contents and a marked congestionof the duodenum.
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Kidneys also showed extreme swellingand distention with urates.Hepatonephrosis was seen
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Hepato-nephrosis lesions
in liver and kidneys.
@kedar karki/KTM
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Enlargement and necrosis
lesions of the liver.
@kedar karki/KTM
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Discolouration of livers
in Hepato-nephrosis.@kedar karki/KTM
A t ti t
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Acute congestion o t eduodenum in Hepato-
nephrosis.@kedar karki/KTM
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Acute nephrosis in a
young broiler chick.@kedar karki/KTM
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Hepato-Nephrosis In
Chicks Amongst the various toxins, aflatoxinis known to cause both hepatic and
kidney lesions consisting ofcongestion, enlargement and a firmappearance with a distended gallbladder.
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Kidneys are swollen, enlarged andcongested while the duodenum isdistended with catarrhal contents.
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Similarly ochratoxins also cause paleyellow discolouration and necrotic liverlesions along with nephrotoxity as thekidneys are enlarged and look pale.
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Citrinin is also said to cause swollenkidneys and necrosis of liver whileOosporiein too cause nephrotoxity andhigh mortality while liver is mottledhaving focal necrosis. The gall bladder isdistended with a translucent green to
yellow bile.
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During the investigations in this case, itwas noticed that birds receiving morethan one type of Fungus contaminated
feed had mortality increased many fold.There was also some relief fromproviding a 2% sugar solution as sourceof drinking water during the initialstages, besides changing the feed. Theproblem is still continuing due to a greatscarcity of quality feed ingredients.
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@kedar karki/KTM