estrogen + progesterone

Watch for thrombus formation, avoid if px has estrogen-

dependent neoplasm risk factors

raloxifene

Selective estrogen receptor modulator (SERM)

alendronate

bisphophonate

risedronate

bisphophonate

zoledronate

Bisphophonategood treatement for malignant

hypercalcemia

pamidronate

Bisphophonategood treatement for malignant

hypercalcemia

ibandronate

bisphophonateToo weak to prevent non-

vertebral fractures

denosumab

RANKL antibodyFor osteoporosis

teriparatide(hPTH 1-34)

Bone anabolic agent

hPTH 1-84 (investigational)

Bone anabolic agentNot approved b/c of

hypercalcemia

fluoride (investigational)

Bone anabolic agent

aluminum hydroxide

oral phosphate binderAvoid b/c of aluminum toxicity

calcium carbonate/acetateoral phosphate binder

Watch for hypercalcemia

sevelamer

oral phosphate binderBest treatment

ergocalciferol

Vitamin D2: equivalent biological activity to D3

calcifediol

25(OH)D

calcitriol

1,25(OH)2D2

doxercalciferol

Synthetic vitamin D analogue, activated in liver

paricalcitol

Synthetic vitamin D analogue

cinacalcet

calcimimetic—decreases PTH secretion

calcium gluconate

given via IV

calcium chloride

given via IV

calcium carbonate

given PO

calcium citrate

given PO

calcium lactate

given PO

potassium phosphate

Inorganic phosphate