Cholelithiasis anaphysio

Click here to load reader

Embed Size (px)

Transcript of Cholelithiasis anaphysio

  • 1. Anatomy and Physiology

2. The Liver Digestive function produces bile Hepatocytes secrete 8001000 of bile per day 3. The Gallbladder pear-shaped sac posterior of liver 3-4 in. long stores and concentrate the bile produced bythe liver (up to tenfold) releases bile into the duodenum of smallintestine fat release of cholecystokinin (CCK) gallbladder contraction bile secretion 4. The BileComponents: cholesterol bile salts bile pigments (e.g. bilirubin) phospholipids (e.g. lecithin) water and body salts (Na+, K+) small amounts of copper and other metals 5. The Bile Yellowish brownish or olive-green liquid Can pass directly from liver into duodenum or Stored in the gallbladder (fasting state) Alkaline to neutralize the acidic chyme (pH7.6-8.6) Function: Emulsifying agent dietary fat fat droplets 6. How we degrade cholesterol 500 mg cholesterol converted to bile acid/day As bile salt and bile acid excreted in feces Bile acid- cholic and chenodeoxycholic acid Bile salt- bile acid conjugated with taurine/glycine Secretion in the bile transported intointestine and eliminated 7. SYNTHESIS OF BILE SALTS 8. Where does the bile go? 9. LiverBile canaliculiBile ducts Common hepatic ductCommon bile ductPancreatic ductHepatopancreaticampulla Duodenum 10. References Digestive Disorders Health Center (2010). WebMD.[Online]. Available at:,articleId-277768.html[Accessed 11 October 2012]. The Liver and Gallbladder (n.d.) CliffsNotes. [Online].Available at,articleId-277768.html [Accessed 11 October 2012]. Champe PLEASE PAKI CITE NG MAAYOS KASI EBOOK UNGAKIN. Wala sya nung front page part. Thanks (222-24)