Boston University The Next Generation · Boston UniversitySlideshow Title Goes Here Boston...
Transcript of Boston University The Next Generation · Boston UniversitySlideshow Title Goes Here Boston...
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
The Next Generation:A Research on Tap Celebrating Postdoctoral Research at BU
September 18, 2017
Research on Tap: The Next Generation
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Zhaoli (Joy) DaiPostdoctoral Fellow
Clinical Epidemiology Research & Training UnitMED
Research on Tap: The Next Generation
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Knee osteoarthritis (OA) Sleep quality and OA
Future studies
• Chronic pain and sleep deprivation are common in OA
• Sleep quality à ? Knee pain• Chronic widespread pain moderated
this relationship
• Intervention studies to identify mediating biomarkers in observed associations in knee OA
• Most common joint disorder• A leading cause of disability • Shares similar metabolic risk factors
as cardio-metabolic diseases
Dietary fiber and OA
• Fiber and health risks• Plausible mechanisms• Findings in two cohort studies• Featured in NY Times, Reuters, etc.
Lifestyle Factors for the Prevention of Knee Osteoarthritis
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Imane El MeouchePostdoctoral AssociateBiomedical Engineering
ENG
Research on Tap: The Next Generation
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Noise in gene expression Diversifying phenotypes and survival
Stochastic Gene Expression and Role in Antibiotic Resistance at the Single Cell Level
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Dries SelsPostdoctoral Fellow
PhysicsCAS
Research on Tap: The Next Generation
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
A: Static B: Moving C: Counter diabatic
Classical Mechanics Quantum Mechanics
Stat
istic
al p
hysi
csCan we exploit quantum phenomena to build better computers, sensors, … ?
Theo
ry
Mac
hine
Lea
rnin
g
Accelerating Quantum Computing
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Todd SponholtzPostdoctoral Fellow
Preventive Medicine & EpidemiologyMED
Research on Tap: The Next Generation
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Physical Environment
Social Environment
ObesityHypertensionDyslipidemia
Diabetes
CVDStroke
Individual Characteristics
DietPhysical Activity
SmokingSleepStress
Physical and social environments and cardiovascular disease risk
Physical and Social Environments and Cardiovascular Disease Risk
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Vural KaraPostdoctoral AssociateMechanical Engineering
ENG
Research on Tap: The Next Generation
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
E.coliinurinePre-Abx
~2hrs later
Susceptible
Resistant
•Bacteriaarecapturedinmicrofluidicchannelwitheitherpressureorelectricfield.
•Voltagefluctuationsandmeanresistancearemeasuredunderaconstantioniccurrentinurine.
(1)Applypressureorvoltagetoforcebacteriaintothecapturezone. (2)Measurevoltage.
Technology Results
• K.L. Ekinci, L. Li, C. Duan, V. Kara, D. Stearns-Kurosawa, US Appl. No. 15/669,069 - Filed on August 4, 2017• V. Kara, C. Duan, K. Gupta S. Kurosawa, D. Stearns-Kurosawa, K.L. Ekinci, submitted.• V. Kara and K.L. Ekinci founded “Fluctuate Diagnostics Corp.”
A Microfluidic Device for Rapid Antibiotic Susceptibility Testing
• Changesinmeanelectricalresistancereflectthegrowthofbacterialpopulation.
Non-motileS.epidermidis
t = 0 t = 2 hrs
Broth
Abx
Broth
Abx Loading 1hr 2hr 3hr 4hr0
5
10
15
20
% C
hang
e in
Res
ista
nce
(DR
/R)
Abx Broth
•Bacterialnanomechanical movementsmodulatevoltage,andthisreflectsbacterialviability.
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Abigail NoycePostdoctoral Fellow
Psychological & Brain SciencesCAS
Research on Tap: The Next Generation
sPCS
iPCS
tgPCS
cIFS
IPS/TOSIPS/TOS
Hig
h-level cognitio
n
Specialized frontal networks for visual & auditory cognition.
Noyce et al. 2017
Visual Auditory
55 2 2-log p
Michalka et al. 2015 Tobyne et al. 2017
Working MemoryAttentionResting-State Functional Connectivity
1
2
3
4
Spatial memory recruits vision areas
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Sarah HokansonDirector
Professional Development & Postdoctoral Affairs
Research on Tap: The Next Generation
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Boston University Slideshow Title Goes Here
Boston University Office of the Vice President and Associate Provost for Research
Thingsweareworkingon:
Professional Development & Postdoctoral Affairs
ProfessionalDevelopment• AGEPgrantfocusedoninclusivementoring• IUSEgrantfocusedonenhancingpostdocteachingskills• Bringabuddy– raffleprizesystemforevents• Individualdevelopmentplans
Community• Onboardingresources• Postdocassociationevents• Recipebook/wellnessopportunities
Benefits• Non-employeepostdochealthcare&MBTA