8/11/2019 Anemia DiagnosticTree.pdf

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8/11/2019 Anemia DiagnosticTree.pdf

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Diagnostic Tree / NAVC Clinicians Brief / July 2010...............................................................................................................................................................................57

Infectiouscause

Ehrlichia Anaplasma Parvovirus FeLV FIV

Depressionby disease 1

Anemia of inflam-matory disease

Cancer-associatedanemia

Chronic liver &kidney disease

Critical illness Hypothyroidism Hypoadrenocorticism

Nonregenerative Anemia

Is animal presenting with acute clinicalsigns of anemia (eg, weakness, pallor,

tachypnea, tachycardia, etc)?

Preregenerative anemiaLow to low-normal

total solids or albuminand globulin levels?

NoYes

Acuteblood loss

Rule outneoplasia, trauma,

coagulopathy,thrombocytopenia,or gastrointestinal

ulceration

Acutehemolyticdisease

Rule out primaryor secondary

IMHA, blood para-sites, Heinz bodyanemia, microan-giopathic anemia

True nonregenerative anemiaDo history, physical examination, and diagnostic

tests indicate that another disease process is occurring?

Bone marrow aspirateor core biopsy

Bone marrowneoplasia

Aplastic anemia Pure red cell aplasia Myelonecrosis Myelophthisis Myelodysplastic

syndrome

Presence of NRBCs with orwithout basophilic stippling?

Lead poisoning Low to low-normal totalserum iron and high to high-

normal transferrin levels?

Yes No

Iron deficiencyanemia

Rule out chronicblood loss

Rule out anemiadue to inflammatorydisease, chronic liverdisease, or folate orcobalamin deficiency

See Aids & Resources, back page, for references and suggested reading.

Yes Yes

Yes No

Presence of microcytosisor hypochromasia?

Yes No

Yes No No

Diagnosis ResultInvestigation