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Microbial models of mammalian drug metabolism By : Radwa Ahmed Taha Advantages of microbial biotransformation of bioactive compounds Definition of microbial biotransformation…
Cluj-Napoca, Romania and MINO R. CAIRA University of Cape Town, South Africa “ ” Edited by Drug Metabolism Current Concepts CORINA IONESCU I. Ha ieganu University of…
REVIEW The Biochemistry of Drug Metabolism – An Introduction Part 1. Principles and Overview by Bernard Testa*a) and Stefanie D. Kr(merb) a) Department of Pharmacy, University…
Slide 1 DRUG METABOLISM Slide 2 The Fate of a Drug Slide 3 Slide 4 BIOTRANSFORMATION Chemical modification of drugs or foreign compounds (xenobiotics) in the body. …
Biotransformation of drugs (Drug metabolism)(Drug metabolism) PharmDr. Pavol Ježko, PhD. Department of Pharmaceutical Chemistry Faculty of Pharmacy, Comenius University…
10 C H A P T E R 2 Pharmacokinetics OVERVIEW Pharmacokinetics is the study of drug disposition in the body and focuses on the changes in drug plasma concentra- tion For any…
Biotransformation of drugs (Drug metabolism)(Drug metabolism) PharmDr. Pavol Ježko, PhD. Department of Pharmaceutical Chemistry Faculty of Pharmacy, Comenius University…
1. DR.VIJAYA KRISHNA Post graduate studentDepartment of Pharmacology GANDHI MEDICAL COLLEGEHyderabad, AP.01 AUG 2012 2. PLAN OF PRESENTATION• INTRODUCTION• DEFINITION•…
1.DR.VIJAYA KRISHNA Post graduate studentDepartment of Pharmacology GANDHI MEDICAL COLLEGEHyderabad, AP.01 AUG 20122. PLAN OF PRESENTATION• INTRODUCTION• DEFINITION•…
BIOTRANSFORMATION BIOTRANSFORMATION Guided by, K.charhate sir presented by, priyanka R Todkari M-PHARM(Q.A.) 1 CONTENT 1)INTRODUCTION. 2)FACTORS AFECTING BIOTRANSFORMATION…
Biotransformation Introduction Foreign and potentially toxic compounds absorbed into biological systems are generally lipophilic substances. They are therefore not ideally…
8/14/2019 Biotransformation BDS 1/32Dr.U.P.RathnakarDr.U.P.Rathnakar MD.DIH.PGDHMMD.DIH.PGDHMK.M.C. Mangalore.K.M.C. Mangalore.Fate of the drug8/14/2019 Biotransformation…
8/12/2019 biotransformation (1) 1/27 B I M M 1 1 8Drug Metabolism Most metabolic products are less pharmacologically activeImportant exceptions: Where the metabolite is more…
Slide 1SITES DRUG BIOTRANSFORMATION of HEPATIC METABOLISM undergo List of DRUGS Absorption Site Intestine & Colon Process Reductive Reaction SULFASALAZINE Slide 2 SITES…
10 Adverse Effects of Drugs and Toxins on the Liver Jan Schjøtt Regional Drug Information Centre RELIS Vest Haukeland University Hospital Norway 1 Introduction More than…
2 Biotransformation of Underutilized Natural Resource to Valuable Compounds in Ionic Liquid: Enzymatic Synthesis of Caffeic Acid Phenethyl Ester Analogues from Immature Coffee…
Biotransformation Biotransformation Siva Nageswararao Mekala Assistant Professor Dept. of clinical Pharmacology Biotransformation It is the chemical transformation of the…
BIOTRANSFORMATION OF BENZALKONIUM CHLORIDES BY IMMOBILIZED CELLS OF PSEUDOMONAS SP. BIOMIG1 by FAHRİ KORAY SAKARYA BS. in Molecular Biology and Genetics, Boğaziçi University,…
1. STEROID BIOTRANSFORMATION • Presented by :- Sudha Chib 130181107 M.Sc(H) bt (2) 2. CONTENTS • INTRODUCTION • TYPES OF STEROIDAL TRANSFORMATION • COMMERCIAL DEVELOPMENT…
BIOTRANSFORMATION OF DRUGS PHASE I: OXIDATION Submitted by:STEFFI K. BABU 1st MPHARM (PHARMACEUTICS) JSSCP, OOTY PHASE I BIOTRANSFORMATION Conversion of drugs from one chemical…