8/11/2019 GNIPST Bulletin 37.3
1/15
12-09-2014G
G
N
N
I
I
P
P
S
S
T
T
U
U
L
L
L
L
T
T
I
I
N
N
2
2
1
1
4
4
12th
September, 2014 Volume No.: 37 Issue No.: 03
Vision
TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE BAS
LEARNING AND PRACTICE
ontentsMessage from PRINCIPAL
Editorial board
Historical article
News Update
Knowledge based Article
Disease Related Breaking
News
Upcoming Events
Drugs Update
Campus NewsStudents Section
Editors Note
Archive
GNIPST Photo Gallery
or your comments/contribution
For ack-Issues,
ailto:[email protected]
GURU NANAK INSTITUTE OF PHARMACEUTICAL
SCIENCE AND TECHNOLOGY
Website:http://gnipst.ac.in
https://plus.google.com/u/0/photos/111714720327580099858/albums/5897323676427099873?sort=7mailto:[email protected]:[email protected]:[email protected]://plus.google.com/u/0/photos/111714720327580099858/albums/5897323676427099873?sort=78/11/2019 GNIPST Bulletin 37.3
2/15
12-09-2014
MESSAGE FROM PRINCIPAL
"It can happen. It does happen.But it can't happen if you quit." Lauren Dane.
We are what we repeatedly do.
Excellence then is not an act, but a habit. Aristotle
It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank tlast years editors and congratulate the newly selected editors for the current year.
Our first consideration is always in the best interest of the students. Our goal is to promote academexcellence and continuous improvement.
I believe that excellence in education is aided by creating a learning environment in which all learners a
supported in maximizing their potential and talents. Education needs to focus on personalized learni
and instruction, while promoting an education system that is impartial, universally accessible, and meetithe needs of all students.
It is of paramount importance that our learners have sufficient motivation and encouragement in order achieve their aims. We are all very proud of you, our students, and your accomplishments and loo
forward to watching as you put your mark on the profession in the years ahead.
The call of the time is to progress, not merely to move ahead. Our progressive Management is looki
forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken
this direction and fruits of these efforts will be received by our students in the near future. Our Teacheare committed and dedicated for the development of the institution by imparting their knowledge and pl
the role of facilitator as well as role model to our students.
The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positi
challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holist
needs of our students.
I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of t
opportunities and meet the challenges with purpose and determination.
Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us this path.
My best wishes to all.
Dr. A. Sengupta
Click here to go at the top
1
8/11/2019 GNIPST Bulletin 37.3
3/15
12-09-2014
EDITORIAL BOARD
CHIEF EDITOR DR. ABHIJIT SENGUPTA
EDITOR MS. JEENATARA BEGUM
ASSOCIATE EDITOR MR. DIPANJAN MANDAL
HISTORICAL ARTICLE
Galen Experimenter in Drug Compounding:Of the men of ancient times whose names are known and revered
among both the professions of Pharmacy and Medicine, Galen,
undoubtedly, is the foremost. Galen (130-200 A.D.) practiced and
taught both Pharmacy and Medicine in Rome; his principles ofpreparing and compounding medicines ruled in the Western
world for 1,500 years; and his name still is associated with that
class of pharmaceuticals compounded by mechanical means -
galenicals. He was the originator of the formula for a cold cream,
essentially similar to that known today. Many procedures Galen
originated have their counterparts in today's modern
compounding laboratories.
NEWS UPDATE
International Literacy Day: (8th September,
2014)The theme of International Literacy Day 2014 is Literacy and
Sustainable Development.
Nicotine withdrawal reduces response to rewardsacross species: (12thSeptember, 2014)While more than half of US smokers try to quit every year, lessthan 10 percent are able to remain smoke-free, and relapsecommonly occurs within 48 hours of smoking cessation. In a first
Click here to go at the top
2
8/11/2019 GNIPST Bulletin 37.3
4/15
12-09-2014
of its kind study on nicotine addiction, scientists measured abehavior that can be similarly quantified across species likehumans and rats, the responses to rewards during nicotinewithdrawal. Learning about withdrawal and difficulty of quitting
can lead to more effective treatments to help smokers quit.From worm muscle to spinal discs: An
evolutionary surprise: (12thSeptember, 2014)Thoughts of the family tree may not be uppermost in the mind of aperson suffering from a slipped disc, but those spinal discs providea window into our evolutionary past. They are remnants of thefirst vertebrate skeleton, whose origins now appear to be olderthan had been assumed. Scientists have found that, unexpectedly,this skeleton most likely evolved from a muscle.
One-minute point-of-care anemia test shows
promise in new study: (12thSeptember, 2014)A simple point-of-care testing device for anemia could providemore rapid diagnosis of the common blood disorder and allowinexpensive at-home self-monitoring of persons with chronicforms of the disease. About a third of the population is at risk for
anemia, which can cause neurocognitive deficits in children, organfailure and less serious effects such as chronic fatigue. Women,children, the elderly and those with chronic conditions such askidney disease are more likely to suffer from anemia.
Combining gut hormone with insulin proves more
effective at controlling type 2 diabetes than
other common treatments: (11th September,
2014)Combined treatment with a drug that mimics the action of a guthormone and basal insulin is more effective at improving bloodsugar control than other anti-diabetic treatments, with similarrates of hypoglycaemia (dangerously low blood sugar levels) andgreater weight loss, a systematic review and meta-analysis shows.
Click here to go at the top
3
8/11/2019 GNIPST Bulletin 37.3
5/15
12-09-2014
Faster way found to create insulin-producing
cells: (11thSeptember, 2014)A study highlighting a protocol to convert stem cells into insulin-
producing cells has been published by researchers. The newprocedure could be an important step in the fight against type 1diabetes. The protocol can turn stem cells into reliable, insulin-producing cells in about six weeks, far quicker than the fourmonths it took using previous methods.
Tipping the balance of behavior: Neurons found
that control social behavior may have
implications for autism: (11
th
September, 2014)Antagonistic neuron populations in the mouse amygdala thatcontrol whether the animal engages in social behaviors or asocialrepetitive self-grooming have been recently discovered byresearchers. Dubbed a 'seesaw circuit,' this discovery may haveimplications for understanding neural circuit dysfunctions thatunderlie autism in humans.
Inflammation may be key to diabetes-heart
disease link: (11th
September, 2014)Inflammation may be the reason high blood sugar levels damageblood vessels, researchers report. Anti-inflammatory medicationsmight someday be used to reduce the risk of blood vessel disease inpeople with diabetes, they say.
Simple method turns human skin cells into
immune strengthening white blood cells: (11th
September, 2014)For the first time, scientists have turned human skin cells intotransplantable white blood cells, soldiers of the immune systemthat fight infections and invaders. The work could let researcherscreate therapies that introduce into the body new white blood
Click here to go at the top
4
8/11/2019 GNIPST Bulletin 37.3
6/15
12-09-2014
cells capable of attacking diseased or cancerous cells oraugmenting immune responses against other disorders.
New genetic targets discovered in fight against
muscle-wasting disease: (11th
September, 2014)Findings of a new study offer the possibility of developing newways of tackling an incurable condition known as muscle-wastingdisease. To date, only six genes have been linked to the illness.Despite rigorous screening, at least 50% of patients have nodetectable mutation in the 6 known genes. Now a breakthroughstudy has discovered two more genes linked to the disease.
Malaria parasites sense and react to mosquito
presence to increase transmission: (11thSeptember, 2014)Many pathogens are transmitted by insect bites. The abundance ofvectors (as the transmitting insects are called) depends onseasonal and other environmental fluctuations. A new articledemonstrates that Plasmodium parasites react to mosquitoesbiting their hosts, and that the parasite responses increasetransmission to the mosquito vector.
Ebola paper demonstrates disease transmissionrate: (11thSeptember, 2014)Transmission rates for each single case of Ebola consistentlyshowed at least one new case of the disease being transmitted.Country-specific analysis of transmission rates in Liberia andSierra Leone showed on average between one and two new casesfor every existing case, research has shown.
Cells put off protein production during times ofstress: (11thSeptember, 2014)When a stressed cell recognizes the buildup of misfolded proteins,it responds by reshuffling its workload, much like a stressed outemployee might temporarily move papers from an overflowinginbox into a junk drawer. The study could lend insight into
Click here to go at the top
5
8/11/2019 GNIPST Bulletin 37.3
7/15
12-09-2014
misfolded protein diseases such as Alzheimer's, ALS, Huntington's,Parkinson's, and type 2 diabetes.
For detail mail toeditor
KNOWLEDGE BASED ARTICLE
Structural States of a Brain Receptor Revealed
Receptors are present on the cell surface serve as keepers whichtransmit signals from inside to the outside. Glutamate receptorsare present on the nerve cells that span the cell membrane. Theglutamate comes in contact with the receptors present on outside,
the receptors change within seconds and opens up withinmilliseconds. This allows small substances like ions to enter thecell.
The process is crucial for communication between the nerve cellsand plays a important role in the development of the brain,learning and memory. The problems associated with the glutamatereceptor functioning are thought to be involved in numerousdisorders including autism, schizophrenia, depression, Parkinsons
disease and some types of cancer.
As reported by Dr. Sriram Subramanian of NIHs National cancerInstitute (NCI) in collaboration with Eunice Kennedy ShriverNational Institute of Child Health and Human Development(NICHD) and others, set out to determine the structure of theGlutamate receptor as it transitions from its resting state to opento Desensitized (reduced response to glutamate) states.
Click here to go at the top
6
mailto:[email protected]:[email protected]:[email protected]8/11/2019 GNIPST Bulletin 37.3
8/15
12-09-2014
Structure of the glutamate receptor,Showing the part where glutamate Bindsoutside the cell and the part that Spans the cell membrane (between the Dottedlines)
A structure of one glutamate receptor variant in its resting state
had previously been determined by using X-ray crystallography.This technique requires a protein to first be crystallized into afixed 3-D shape. However, capturing the proteins multiple statesin a crystal is challenging, and could potentially trap subtlymisfolded or incorrect structures.In findings that appeared online on August 3, 2014, in Nature, theteam used an imaging technique called cryo-electron microscopy.This method allowed them to capture high-resolution snapshots ofreceptors in several transitional stages.The group analyzed detailed images of different types of glutamatereceptors and captured the receptors in different states. Theydetermined that the transition of the protein from the resting toopen states involved a corkscrew-like rotational motion within theprotein.
Click here to go at the top
7
8/11/2019 GNIPST Bulletin 37.3
9/15
12-09-2014
The shift from open to desensitized states required much largerrearrangements.The scientists note that while several technical hurdles remain, thetechnique will allow them to analyze the structures of many other
proteins, as well as study receptor-drug interactions.Anurag Chanda
Student, GNIPST
B.Pharm, 4thYear
DISEASE RELATED BREAKING NEWS
Ebola virus disease: (10thSeptember, 2014)
Between 2 and 9 September 2014, there have been 31 more cases ofEbola virus disease (EVD) reported in the Democratic Republic of
the Congo (DRC), increasing the cumulative number of cases to 62
(14 confirmed, 26 probable, and 22 suspect). In total, 35 deaths
have been reported (9 confirmed and 26 probable).Read more
UPCOMING EVENTS
5
th
International Conference on Stem Cells and Cancer 2014, JNUConvention Centre, New Delhi, India from 8-10 November, 2014
DRUGS UPDATES
FDA Approves New Obesity Drug Contrave: (11th
September, 2014)The U.S. Food and Drug Administration's approval of a new
weight-loss drug marks the third time the agency has given itsblessing to a new diet medication since 2012. Called Contrave, themedicine is a combination of two approved drugs: naltrexone,which treats alcohol and drug addiction, and bupropion, whichtreats depression and seasonal affective disorder and is used tohelp smokers quit.Read more
Click here to go at the top
8
http://www.who.int/csr/don/2014_09_10_ebola/en/http://www.who.int/csr/don/2014_09_10_ebola/en/http://d/Jeenat/Bulletin%2034.3_1/New%20Folder/UPCOMING%20EVENTS.docxhttp://www.drugs.com/news/fda-approves-new-obesity-contrave-53101.htmlhttp://www.drugs.com/news/fda-approves-new-obesity-contrave-53101.htmlhttp://www.drugs.com/news/fda-approves-new-obesity-contrave-53101.htmlhttp://d/Jeenat/Bulletin%2034.3_1/New%20Folder/UPCOMING%20EVENTS.docxhttp://www.who.int/csr/don/2014_09_10_ebola/en/8/11/2019 GNIPST Bulletin 37.3
10/15
12-09-2014
CAMPUS NEWS
Today, on 5th September, 2014 the students of GNIPST have
arranged a wonderful Teachers Day Programme. On behalf of allthe teachers of GNIPST I would like to thank our beloved
students.
The Freshers welcome programme was held on 14thAugust, 2014.Welcome 1styear students.
We congratulate the following M.Pharm. final year students whohave made their positions in different pharmaceutical companies.
Anirban Banerjee (Emami Ltd.)Mahender Roy (Stadmed private Ltd.)
We congratulate the following B.Pharm. final year students fortheir success.
Samadrita Mukherjee (Abbott India Ltd.)
Suman Sarkar (Tata Medical Centre-Apollo Pharmacy)
Shrewashee Mukherjee (Fresenius Kabi-Parenteral Nutrition)
Avishek Naskar (Glaxo SmithKline-Marketing)Bappaditya Manik (USV Limited)
Sarbani Das (Nutri Synapzz-Marketing)
Ankita Roy (Nutri Synapzz-Marketing)
Rahul Mitra (B M Pharmaceuticals-Production)
The following B.Pharm. final year students have qualified, GPAT-2014. We congratulate them all.
Utsha Sinha
Satarupa Bhattacharya
Sandipan Sarkar
Purbali Chakraborty
Reminiscence, 2014(GNIPST Reunion) was held in Collegecampus on 2ndFebruary,2014.
Click here to go at the top
9
8/11/2019 GNIPST Bulletin 37.3
11/15
12-09-2014
1st Annual Sports of GNIPST was held on 3rd February,2014 inCollege campus ground.
An industrial tour and biodiversity tour was conducted in Sikkim
for B.Pharm and B.Sc. students under the supervision of Mr. AsisBala, Ms. Jeentara Begum and Ms. Moumita Chowdhury.
B.Pharm 3rd year won the GNIPST Football Champions trophy,2013. B.Pharm 3rdyear won the final match 1-0 against B.Pharm 2nd
year. Deep Chakrabortywas the only scorer of the final.
STUDENTS SECTION
WHO CAN ANSWER FIRST????
Story of my life published in 1903 is the
autobiography of which famous
personality?
Who is the first Arjuna awardee in
cricket?
Answer of Previous Issues Questions
A) 5th October
B) 1962
Click here to go at the top
10
8/11/2019 GNIPST Bulletin 37.3
12/15
12-09-2014
Identify the lady
Answer of Previous Issues Image
Anne Sulivan
Send your thoughts/
Quiz/Puzzles/games/write-ups or any other
contributions for Students Section
answ ers of this Section at [email protected]
EDITORS NOTE
It is a great pleasure for me to publish the 3rd
issue of 37th
Volume
of GNIPST BULLETIN. All the followers of GNIPST BULLETINare able to avail the bulletin through facebook account GNIPST
bulletin I am very much thankful to all the GNIPST members and
readers who are giving their valuable comments, encouragements
and supports. I am also thankful to Dr. Abhijit Sengupta, Director
of GNIPST for his valuable advice and encouragement. Special
thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar
and Mr. Soumya Bhattacharya for their kind co-operation and
technical supports. Thank you Mr. Soumya Bhattacharyafor the
questionnaires of the student section. An important part of the
improvement of the bulletin is the contribution of the readers. You
are invited to send in your write ups, notes, critiques or any kind of
contribution for the forthcoming special and regular issue.
Click here to go at the top
11
mailto:[email protected]:[email protected]:[email protected]8/11/2019 GNIPST Bulletin 37.3
13/15
12-09-2014
ARCHIVE
Students of GNIPST organized pre puja celebration programme,Saaranya on 7thOctober, 2013 in college Auditorium.
GNIPST organized a garment distribution programme on 28thSeptember, 2013 at Dakshineswar Kali Temple and Adyapith,
Kolkata. On this remarkable event about hundred people have
received garments. More than hundred students and most of the
faculties participated on that day with lot of enthusiasm.
GNIPST celebrated World Heart Day (29th
September) andPharmacists Day (25thSeptember)on 25thand 26thSeptember,
2013 in GNIPST Auditorium. A seminar on Violence against
woman and female foeticide was held on GNIPST Auditorium on
25th September organized by JABALA Action Research
Organization. On 26thSeptember an intra-college Oral and Poster
presentation competition related to World Pharmacists day and
Heart day was held in GNIPST. Ms. Purbali Chakraborty ofB.Pharm 4th year won the first prize in Oral Presentation. The
winner of Poster presentation was the group of Ms. Utsa Sinha,
Mr. Koushik Saha and Mr. Niladri Banerjee(B.Pharm 4thyear). A
good number of students have participated in both the
competition with their valuable views.
Teachers daywas celebrated on 5thSeptember, 2013 by the
students of GNIPST in GNIPST Auditorium.
Azalea exotic flower ) , the fresher welcome programme for
newcomers of GNIPST in the session 2013-14 was held on 8th
August in GNIPST Auditorium.
Click here to go at the top
12
8/11/2019 GNIPST Bulletin 37.3
14/15
12-09-2014
One day seminar cum teachers development programme forschool teachers on the theme of Recent Trends of Life Sciences
in Higher Education organized by GNIPST held on 29th June,
2013 at GNIPST auditorium. The programme was inaugurated byProf . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy
Director of JIS Group and Dr. Abhijit Sengupta, Director cum
Principal of GNIPST with lamp lighting. The programme started
with an opening song performed by the B.Pharm students of this
institute. The seminar consists of a series of lectures, video
presentations and poster session. On the pre lunch session 4
lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata
Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty
respectively. On their presentation the speakers enlighten the
recent development of Pharmacy, Genetics and Microbiology and
their correlation with Life Sciences. On the post lunch session, Ms.
Saini Setua and Ms. Sanchari Bhattacharjee explained the recent
development and career opportunities in Biotechnology and
Hospital Management. The programme was concluded with
valedictory session and certificate distribution.About 50 Higher secondary school teachers from different
schools of Kolkata and North& South 24 Parganas district of West
Bengal participated in this programme. A good interactive session
between participants and speakers was observed in the seminar.
The seminar was a great success with the effort of faculties, staffs
and students of our Institute. It was a unique discussion platform
for school teachers and professional of the emerging and newerbranches of Life Science.
The general body meeting of APTI, Bengal Branch has been
conducted at GNIPST on 15thJune, 2012. The program started with
a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural
Click here to go at the top
13
8/11/2019 GNIPST Bulletin 37.3
15/15
12-09-2014
Products, JU on the skill to write a good manuscript for
publication in impact journals. It was followed by nearly two hour
long discussion among more than thirty participants on different
aspects of pharmacy education. Five nonmember participants
applied for membership on that very day.
GNIPST is now approved by AICTE and affiliated to WBUT for
conducting the two years post graduate course (M.Pharm)
in P H A R M A C O L O G Y .The approved number of seat is 18.
The number of seats in B.Pharm. has been increased from 60 to
120.
AICTE has sanctioned a release of grant under Research
Promotion Scheme (RPS) during the financial year 2012-13to
GNIPST as per the details below:
a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical
Science & Technology.
b.Principal Investigator:Dr. LopamudraDutta.
c. Grant-in-aid sanctioned:Rs. 16,25000/- onlyd.Approved duration: 3 years
e. Title of the project: Screening and identification of potential
medicinal plant of Purulia & Bankura districts of West Bengal
with respect to diseases such as diabetes, rheumatism, Jaundice,
hypertension and developing biotechnological tools for enhancing
bioactive molecules in these plants.
Click here to go at the top
14