Gnipst Bulletin 23.3

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GNIPST BULLETIN 2013

15th March 2013 Volume No.: 23 Issue No.: 03

ContentsMessage from GNIPS

Letter to the EditorNews Update

Disease Outbreak Ne

Health Awareness

Forth Coming Events

Drugs Update

Campus News

Students Section

Editors Note

Archive

Vision

TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O

PHARMACEUTICAL AND BIOLOGICAL SCIENCE

EDITOR: Debabrata Ghosh DastidarGURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE ANDTECHNOLOGY

GNIPST Photo Gallery

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MESSAGE FROM GNIPSTAll the members of GNIPST are proud to publish the 23rdVolume of

GNIPST BULLETIN. This bulletin has successfully completed its

twenty months journey. We hope it has kept the readers updated of

recent activities in pharmaceutical & biological sciences and also

introduced them with the different activities of our esteemed

institution. We are thankful to all of you for your great cooperation

& support and are looking forward to the same in future.

LETTER TO THE EDITOR.

NEWS UPDATE

Temp-Controlled 'Nanopores' May Allow Detailed

Blood Analysis (08 MARCH 2013)Tiny biomolecular chambers called nanopores that can be

selectively heated may help doctors diagnose disease more

effectively, according to a new research.Read moreAnti-Aging Drug Breakthrough (08 MARCH 2013)

Drugs that combat aging may be available within five years,

following landmark work. The work finally demonstrates that a

single anti-aging enzyme in the body can be targeted, with the

potential to prevent age-related diseases and extend lifespans. Four

Click here to go at the top1
http://www.sciencedaily.com/releases/2013/03/130308183832.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130308183832.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130308183832.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130308183832.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29


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thousand synthetic activators, which are 100 times as potent as a

single glass of red wine, have been developed -- the best three are in

human trials.Read more

Biological Tooth Replacement Is a Step Closer.

(08 MARCH 2013)

Scientists have developed a new method of replacing missing teeth

with a bioengineered material generated from a person's own gum

cells. Current implant-based methods of whole tooth replacementfail to reproduce a natural root structure and, as a consequence of

the friction from eating and other jaw movement, loss of jaw bone

can occur around the implant.Read more

Length of DNA Strands Can Predict Life

Expectancy (09 MARCH 2013)

Can the length of strands of DNA in patients with heart disease

predict their life expectancy? Researchers who studied the DNA of

more that 3,500 patients with heart disease, say yes it can.Read moreStore Donated Blood for More Than 3 Weeks?

Say NO (Nitric Oxide) (10 MARCH 2013)

Transfusion of donated blood more than three weeks old results in

impaired blood vessel function, a new study of hospital patients

shows. Blood banks now consider six weeks to be the maximum

http://www.sciencedaily.com/releases/2013/03/130308111312.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130308111312.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130308183819.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130308183819.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130310164232.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130310164232.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130310164232.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130308183819.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130308111312.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29


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permitted storage time of blood for use in transfusion, but recent

studies have suggested transfusing blood stored for more than a few

weeks has adverse effects in patients undergoing cardiac surgery or

critical care.Read more Aspirin May Lower Melanoma Risk

(11 MARCH 2013)

A new study has found that women who take aspirin have a reduced

risk of developing melanoma -- and that the longer they take it, the

lower the risk. The findings suggest that aspirin's anti-

inflammatory effects may help protect against this type of skin

cancer.Read more Immune Cells Cluster and Communicate 'Like

Bees,' Researcher Says (13 MARCH 2013)

The immune system's T cells, while coordinating responses to

diseases and vaccines, act like honey bees sharing information

about the best honey sources, according to a new study.Read more Bitter Melon JuicePrevents Pancreatic Cancer in

Mouse Models (12MARCH 2013

)A new study shows that bitter melon juice restricts the ability of

pancreatic cancer cells to metabolize glucose, thus cutting the cells'

energy source and eventually killing them.Read more

http://www.sciencedaily.com/releases/2013/03/130310164225.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130310164225.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130311091531.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130311091531.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130313131906.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130313131906.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130312134920.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130312134920.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130312134920.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130313131906.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130311091531.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130310164225.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29


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Computer Models Predict How Patients Will

Respond to HIV Drugs Without the Need for

Resistance Testing (14 MARCH 2013)

Computer models can predict how HIV patients whose drug

therapy is failing will respond to a new treatment. Crucially for

patients in poorer countries, the models do not require the results

of expensive drug resistance tests to make their predictions. The

study also showed that the models were able to identify alternativedrug combinations that were predicted to work in cases where the

treatment used in the clinic had failed, suggesting that their use

could avoid treatment failure.Read more Tobacco Industry Appears to Have Evaded FDA

Ban On 'Light' Cigarette Descriptors

(13 MARCH 2013)

New research shows one year after the U.S. government passed a

law banning such descriptors as "light," "mild," and "low" on

cigarette packages, smokers can identify their brands because of

color-coding that tobacco companies added to "light" packs afterthe ban. These findings suggest the companies have been able to

evade the ban on misleading wording and still convey false and

http://www.sciencedaily.com/releases/2013/03/130313214015.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130313214015.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130313214015.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29


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deceptive message that lights are safer than "regular" cigarettes.

Read more Goats' Milk With Antimicrobial Lysozyme Speeds

Recovery from Diarrhea (13 MARCH

2013)

Milk from goats that were genetically modified to produce higher

levels of lysozyme, a human antimicrobial protein, has proved

effective in treating diarrhea in young pigs and may one day be usedto help prevent human diarrheal diseases that each year claim the

lives of 1.8 million children around the world.Read more

HEALTH AWARENESS

LYMPHATIC FILARIASIS

Lymphatic filariasis, commonly known as

elephantiasis, is a neglected tropical disease.

Infection occurs when filarial parasites are

transmitted to humans through mosquitoes.

When a mosquito with infective stage larvae

bites a person, the parasites are deposited on the

person's skin from where they enter the body. The larvae then

http://www.sciencedaily.com/releases/2013/03/130313182251.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130313182140.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130313182140.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130313182140.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29http://www.sciencedaily.com/releases/2013/03/130313182251.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29


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migrate to the lymphatic vessels where they develop into adult

worms in the human lymphatic system.

Infection is usually acquired in childhood, but the painful and

profoundly disfiguring visible manifestations of the disease occur

later in life. Whereas acute episodes of the disease cause

temporary disability, lymphatic filariasis leads to permanent

disability.

Currently, more than 1.4 billion people in 73 countries are at risk.

Approximately 65% of those infected live in the WHO South-EastAsia Region, 30% in the African Region, and the remainder in

other tropical areas.

Lymphatic filariasis afflicts over 25 million men with genital

disease and over 15 million people with lymphoedema. Since the

prevalence and intensity of infection are linked to poverty, its

elimination can contribute to achieving the United Nations

Millennium Development Goals.

Cause and transmission

Lymphatic filariasis is caused by infection with nematodes(roundworms) of the family Filariodidea. There are three types of

these thread-like filarial worms:

Wuchereria bancrofti, which is responsible for 90% of the cases

Brugia malayi, which causes most of the remainder of the cases



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B. timori, which also causes the diseases.

Adult worms lodge in the lymphatic system and disrupt the

immune system. They live for 6-8 years and, during their life time,

produce millions of microfilariae (small larvae) that circulate in

the blood.

Lymphatic filariasis is transmitted by different types of

mosquitoes for example by the Culex mosquito, widespread

across urban and semi-urban areas; Anopheles mainly in rural

areas, and Aedes, mainly in endemic islands in the Pacific.

Symptoms

Lymphatic filariasis infection involves asymptomatic, acute, and

chronic conditions. The majority of infections are asymptomatic,

showing no external signs of infection. These asymptomatic

infections still cause damage to the lymphatic system and the

kidneys as well as alter the body's immune system.

Acute episodes of local inflammation involving skin, lymph nodes

and lymphatic vessels often accompany the chronic lymphoedema

or elephantiasis. Some of these episodes are caused by the body'simmune response to the parasite. However most are the result of

bacterial skin infection where normal defences have been partially

lost due to underlying lymphatic damage.



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When lymphatic filariasis develops into chronic conditions, it

leads to lymphoedema (tissue swelling) or elephantiasis

(skin/tissue thickening) of limbs and hydrocele (fluid

accumulation). Involvement of breasts and genital organs is

common.

Such body deformities lead to social stigma, as well as financial

hardship from loss of income and increased medical expenses. The

socioeconomic burdens of isolation and poverty are immense.

Treatment and prevention

The recommended regimen for treatment through mass drug

administration (MDA) is a single dose of two medicines given

together - albendazole (400 mg) plus either ivermectin (150-200

mcg/kg) in areas where onchocerciasis (river blindness) is also

endemic or diethylcarbamazine citrate (DEC) (6 mg/kg) in areas

where onchocerciasis is not endemic. These medicines clear

microfilariae from the bloodstream.

Mosquito control is another measure that can be used to suppress

transmission. Measures such as insecticide-treated nets or indoorresidual spraying may help protect populations in endemic

regions from infection.

Patients with chronic disabilities like elephantiasis,

lymphoedema, or hydrocele are advised to maintain rigorous



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hygiene and take necessary precautions to prevent secondary

infection and aggravation of the disease condition.

DISEASE OUTBREAK NEWS

FORTHCOMING EVENTS

DRUGS UPDATES

FDA approves Lymphoseek to help locate lymph

nodesin patients with certain cancers (13

FEBRUARY 2013)

The U.S. FDA approved Lymphoseek (technetium Tc 99mtilmanocept) Injection, a radioactive diagnostic imaging agent that

helps doctors locate lymph nodes in patients with breast cancer or

melanoma who are undergoing surgery to remove tumor-draining

lymph nodes. Read more

CAMPUS NEWS

The poster Oolong tea as a source of natural antioxidant, presented

in the national seminar, organized by GNIT, Panihati, Kol-114, by

http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm343525.htmhttp://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm343525.htmhttp://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm343525.htm


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Anirban Banerjee (M.Pharm., 1st yr.), Dibya Das (B.Pharm., 4th yr.),

Rahul Deb Mondal (M.Pharm., 1st yr.), was awarded third prize.

STUDENTS SECTION

WHO CAN ANSWER FIRST???() William and James Horlick were associated

with invention of which patented food

product?

() Which type of classification system wascreated by Melvil Dewey?

Answer of Previous Issue Question:A) Pseudomonus putida B)Keypad

Send your thoughts/ Quiz/Puzzles/games/write-ups or any other contributions for Students Section

& answers of this Section at [email protected] NOTE

I am very happy to publish the 3rd issue of 23rd Volume of GNIPST

BULLETIN. It is my great pleasure to introduce you to the newly

launched facebook account GNIPST bulletin. You are cordially

mailto:[email protected]:[email protected]:[email protected]


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invited to add this account to your friend list. The current issues will

also be directly available on facebook.

I would like to convey my thanks to all the GNIPST members and

the readers for their valuable comments, encouragement& supports.

Special thanks to Dr. Prerona Saha for her advice; Mr. Soumya

Bhattacharya, for his contribution instudents section.

It would be my great pleasure to receive the contributions,

suggestions & feedback from your desk for further upliftment of this

deliberation GNIPST BULLETIN.



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ARCHIVE

The general body meeting of APTI, Bengal Branch has been

conducted at GNIPST on 15th

June, 2012. The programme startedwith a nice presentation by Dr. Pulok Kr. Mukherjee, School of

Natural Products, JU on the skill to write a good manuscript for

publication in impact journals. It was followed by nearly two hour

long discussion among more than thirty participants on different

aspects of pharmacy education. Five nonmember participants

applied for membership on that very day.

GNIPST is now approved by AICTE and affiliated to WBUT for

conducting the two years post graduate course (M.Pharm) in

PHARMACOLOGY. The approved number of seat is 18.The number of seats in B.Pharm. has been increased from 60 to 120.

2nd World Congress on Ga-68 (Generators and Novel Radiopharmaceuticals),

Molecular Imaging (PET/CT), Targeted Radionuclide Therapy, and Dosimetry

(SWC-2013) : On the Way to Personalized Medicine

Dates 28 Feb 2013 02 Mar 2013

Location: Chandigarh, India.Details. AICTE has sanctioned a release of grant under Research

Promotion Scheme (RPS) during the financial year 2012-

13to GNIPST as per the details below:

http://www.2ndworldcongress-ga-68.de/http://www.2ndworldcongress-ga-68.de/http://www.2ndworldcongress-ga-68.de/http://www.2ndworldcongress-ga-68.de/


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a. Beneficiary Institution: Guru Nanak Institution of

Pharmaceutical Science & Technology.

b. Principal Investigator: Dr. LopamudraDutta.

c. Grant-in-aid sanctioned:Rs. 16,25000/- only

d. Approved duration: 3 years

e.Title of the project: Screening and identification of potential

medicinal plant ofPurulia&Bankuradistricts of West Bengal with

respect to diseases such as diabetes, rheumatism, Jaundice,

hypertension and developing biotechnological tools for enhancingbioactive molecules in these plant.


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