Program PDF Saturday, March 9, 2013 Updated: 01-24-13...Rivaroxaban in the Setting of Continued Dual...

Program PDF Updated: 01-24-13 Saturday, March 9, 2013

ACC.13 | Program PDF | Saturday, March 9, 2013 | Page 1 of 79

Arrhythmias‐SymposiumSession#600PharmacologyProgramI‐AntiarrhythmicsinAtrialFibrillation:Uses,Abuses,andHowDangerousAreTheseDrugs?Saturday,March9,2013,7a.m.‐8:30a.m.West,Room2010CMEHours:1.5/CNEHours:1.5 Co‐Chair: Joseph S. Alpert Co‐Chair: David Parra 7:00 a.m. Antiarrhythmics in Atrial Fibrillation: Uses, Abuses, and How Dangerous Are These Drugs? Eric N. Prystowsky Panelist: Jerry Bauman Panelist: Melanie T. Gura Panelist: Gerald V. Naccarelli AcuteCoronarySyndromes‐SymposiumSession#601JointSymposiumoftheAmericanAssociationforClinicalChemistryandtheAmericanCollegeofCardiology:HighSensitivityTroponinAssaysAreComing:HowtoExploittheBenefitsandAvoidthePainSaturday,March9,2013,8a.m.‐9:30a.m.North,Room120CMEHours:1.5/CNEHours:1.5 Co‐Chair: Allan S. Jaffe Co‐Chair: L. Kristin Newby 8:00 a.m. Analytical Issues with hscTn Assays Fred S. Apple 8:18 a.m. What Is a Normal with hscTn Assays Alan Wu, San Francisco, CA 8:36 a.m. Defining a Changing Pattern: Not So Simple Allan S. Jaffe, Rochester, MN 8:54 a.m. The Help hscTn Assays Can Provide in Evaluating Patients with Possible Acute Coronary Syndromes David A. Morrow, Boston, MA 9:12 a.m. Using hscTn for Risk Stratification in Non‐Acute Patients James L. Januzzi, Jr., Boston, MA AcuteCoronarySyndromes‐OralContributionsSession#901ACS:NewAgentsandApproachesSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3001CMEHours:1.5/CNEHours:1.5 Co‐Chair: Somjot Singh Brar Co‐Chair: Peter B. Berger 8:00 a.m. Ticagrelor versus Clopidogrel in Patients with Non‐ST‐Elevation Acute Coronary Syndrome: Results from the PLATO Trial Daniel Lindholm, Christoph Varenhorst, Christopher Cannon, Robert Harrington, Anders Himmelmann, Juan Maya, Steen Husted, Hugo Katus,

Philippe Steg, Robert Storey, Lars Wallentin, Stefan K. James, Uppsala Clinical Research Center, Uppsala, Sweden 8:15 a.m. Characterization of the Myocardial Infarction Endpoints, Impact of Event Adjudication, and Ticagrelor Effects in the Platelet Inhibition and Patient Outcomes (PLATO) Trial Kenneth W. Mahaffey, Daniel Wojdyla, Stefan James, Hugo Katus, Steen Husted, Philippe Steg, Christopher Cannon, Richard Becker, Claes Held, Nardev Khurmi, Debra Montgomery, Anders Himmelmann, Robert Harrington, Lars Wallentin, Duke Clinical Research Institute, Durham, NC, USA 8:30 a.m. Rivaroxaban Reduces Spontaneous and Large Myocardial Infarctions: Findings from the ATLAS ACS 2 ‐ TIMI 51 Trial Matthew Cavender, Eugene Braunwald, C. Michael Gibson, Stephen Wiviott, Sabina Murphy, Marcos Amuchastegui, Anton Oude Ophuis, Maarten van Hessen, Jessica Mega, TIMI Study Group, Brigham and Women's Hospital, Boston, MA, USA 8:45 a.m. Rivaroxaban in the Setting of Continued Dual Antiplatelet Therapy: Findings from the ATLAS ACS 2‐TIMI 51 Trial Jessica L. Mega, Eugene Braunwald, Sabina Murphy, Alexei Plotnikov, Nancy Cook‐Bruns, Philip Aylward, Vijay Chopra, Runlin Gao, Jose Nicolau, C. Michael Gibson, TIMI Study Group, Brigham and Women's Hospital, Boston, MA, USA 9:00 a.m. A Pharmacogenomic Approach to Antiplatelet Therapy in STEMI Patients: ReAssessment of Anti‐Platelet Therapy Using an InDividualized Strategy in Patients with ST‐Elevation Myocardial Infarction (The RAPID STEMI Study) Derek Yiu Fai So, George Wells, Ruth McPherson, Marino Labinaz, Chris Glover, Michel Le May, Alexander Dick, Michael Froeschl, Jean‐Francois Marquis, Nitan Garg, Jordan Bernick, Luan Tran, Benjamin Hibbert, Jason Roberts, University of Ottawa Heart Institute, Ottawa, Canada 9:15 a.m. Cost‐Effectiveness of Universal or Phenotype‐Driven Selection of Dual Antiplatelet Treatment in Acute Coronary Syndrome Craig I. Coleman, Brendan Limone, Soyon Lee, University of Connecticut, Storrs, CT, USA AcuteCoronarySyndromes‐OralContributionsSession#902ACS:VulnerableandUnderrepresentedPopulationsSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3020CMEHours:1.5/CNEHours:1.5 Co‐Chair: Sanjay Kaul Co‐Chair: Andrew D. Michaels 8:00 a.m. Sex‐Related Effectiveness of Bivalirudin versus Abciximab and Heparin in NSTEMI: Lessons from the Intracoronary Stenting and Antithrombotic Regime: Rapid Early Action for Coronary Treatment (ISAR‐REACT‐4) Trial David Jochheim, FJ Neumann, Gjin Ndrepepa, lamin king, Stefanie Schulz, Joerg Hausleiter, Jurgen Pache, Ilka Ott, Robert Byrne, Steffen Massberg, Adnan Kastrati, Julinda Mehilli, Klinikum der Universitaet Munich, Munich, Germany 8:15 a.m. Undertreatment of Elderly Patients >80‐Years with Acute Coronary Syndrome Despite High Risk and Similar Benefits from Evidence‐Based Treatment as at Younger Age: Results from Swedeheart



Claes Held, Per Johanson, Annika Edberg, Olle Bergström, Jörgen Cronblad, Karin Hellström Angerud, Thomas Kellerth, Johan Lugnegård, Ewa Mattsson, Anette Sandström, Monica Sterner, Lars Wallentin, Tomas Jernberg, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden 8:30 a.m. Prevalence and Prognostic Impact of Renal Insufficiency in ST‐Elevation Myocardial Infarcation from a Gender Perspective: Data from a Large Prospective Cohort Sofia Sederholm Lawesson, Joakim Alfredsson, Karolina Szummer, Mats Fredrikson, Eva Swahn, Department of Medical and Health Sciences, Division of Cardiovascular Medicine, Linkoping, Sweden 8:45 a.m. The Obesity Paradox: The Importance for Long‐Term Outcomes in Non‐ST‐Elevation Myocardial Infarction ‐ The CRUSADE Experience Emily Obrien, Emil Fosbol, Szu‐Po Peng, Karen Alexander, Matthew Roe, Eric Peterson, Duke Clinical Research Institute, Durham, NC, USA 9:00 a.m. The CHADS2 and CHA2DS2‐VASc Scores Predict the Occurrence of Stroke in Acute Coronary Syndrome Patients without Atrial Fibrillation Stephen Wilton, Danielle A. Southern, Mei Zhang, Diane Galbraith, William A. Ghali, Merril Knudtson, Brent Mitchell, APPROACH Investigators, University of Calgary, Calgary, Canada 9:15 a.m. Increased Incidence of Acute Coronary Syndrome following Hurricane Katrina in New Orleans: The Impact Continues John Moscona, Sumit Tiwari, Kevin DeAndrade, Henry Quevedo, Matthew Peters, Kartik Munshi, Srivastav Sudesh, Patrice Delafontaine, Anand Irimpen, Tulane University Heart & Vascular Institute, New Orleans, LA, USA Arrhythmias‐MeettheExpertsSession#200DifficultClinicalScenariosinAtrialFibrillationSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3018CMEHours:1.5/CNEHours:1.5 Co‐Chair: Douglas L. Packer Panelist: Samuel Asirvatham Panelist: John D. Day Panelist: Barry H. Greenberg Panelist: Peter Kowey 8:00 a.m. CASE PRESENTATION: A Patient with Symptomatic Atrial Fibrillation and Heart Failure Peter Leong‐Sit, London, Canada 8:05 a.m. Panel Discussion 8:25 a.m. Question and Answer 8:45 a.m. CASE PRESENTATION: A Patient with Atrial Fibrillation, High Chads Score and High Risk for Bleeding Bindi K. Shah, Philadelphia, PA 8:50 a.m. Panel Discussion 9:10 a.m. Question and Answer

Arrhythmias‐OralContributionsSession#903ManagementIssuesinthePacemakerandICDPatientSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3009CMEHours:1.5/CNEHours:1.5 Co‐Chair: Bruce D. Lindsay Co‐Chair: Bruce L. Wilkoff 8:00 a.m. Influence of Different Beta‐Blockers on Inappropriate Therapy in the MADIT‐CRT Trial Martin Huth Ruwald, Abeer Abu‐Zeitone, Christian Jøns, Anne‐Christine Ruwald, Scott McNitt, Valentina Kutyifa, Wojciech Zareba, Arthur Moss, University of Rochester Medical Center, Rochester, NY, USA, Gentofte Hospital, Hellerup, Denmark 8:15 a.m. Device Detected Atrial Fibrillation and Risk for Stroke: An Analysis of More than 10,000 Patients from the SOS AF Project (Stroke Prevention Strategies Based on Atrial Fibrillation Information from Implanted Devices) Taya Glotzer, Giuseppe Boriani, Massimo Santini, Teena West, Mirko De Melis, Milan Sepsi, Maurizio Gasparini, Thorsten Lewalter, A. John Camm, Daniel Singer, Medtronic Inc., Maastricht, The Netherlands 8:30 a.m. Externalization of Conductor Cables in QuickSite and QuickFlex Left Ventricular Leads Madhu Reddy, Ajay Vallakati, Pramod Janga, Suresh Sharma, Anand Pillai, Raghuveer Dendi, Martin Emert, Loren Berenbom, Rhean Linette Pimentel, Dhanunjaya Lakkireddy, University of Kansas Medical Center, Kansas City, KS, USA 8:45 a.m. Coronary Sinus Level of Galectin‐3 is a Better Predictor than Peripheral Venous Level of Major Adverse Cardiac Events in Patients with Cardiac Resynchronization Therapy Quynh A. Truong, Wai‐ee Thai, Jackie Szymonifka, Sandeep Basnet, Bryan Wai, Zachary Grunau, Jonathan Beaudoin, Chelsea L. Smith, Adefolakemi Babatunde, Olujimi Ajijola, Jagmeet Singh, James Januzzi, Massachusetts General Hospital, Boston, MA, USA 9:00 a.m. Cardiac Perforation from Implantable Cardioverter‐Defibrillator Lead Placement and In‐Hospital Adverse Events and Mortality: Insights from the NCDR® Jonathan Hsu, Paul Varosy, Haikun Bao, Thomas Dewland, Jeptha Curtis, Gregory Marcus, University of California, San Francisco, San Francisco, CA, USA, Yale University School of Medicine, New Haven, CT, USA 9:15 a.m. Activation Timing Distinguishes Ventricular Tachycardia from Sinus Rhythm in Implantable Cardioverter‐Defibrillators Michael E. Mollerus, Essentia Health, Duluth, MN, USA ChronicCAD/StableIschemicHeartDisease‐OralContributionsSession#910TheCuttingEdgeinRevascularizationforSIHDSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3014CMEHours:1.5/CNEHours:1.5 Co‐Chair: Spencer B. King Co‐Chair: Jacqueline E. Tamis‐Holland 8:00 a.m.



The Effect of Patient Education in Decision‐Making Regarding Elective Percutaneous Coronary Intervention Mohammad Amin Kashef, Laura Scherer, Brian Zikmund‐Fisher, Megan Coylewright, Henry H. Ting, Michael B. Rothberg, Baystate Medical Center, Springfield, MA, USA, Cleveland Clinic, Cleveland, OH, USA 8:15 a.m. Optical Coherence Tomography‐Guided Antiplatelet Therapy in Patients with Coronary Artery Disease and Cancer: The PROTECT‐OCT Registry Cezar Iliescu, Jake Thomas LeBeau, Guilherme Silva, Simone Frusina, Muskan Agarwal, Gloria Iliescu, Gerryross Tomakin, George Manoukian, Jose Banchs, Peter Kim, Saamir Hassan, Jean‐Bernard Durand, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA, University of Texas Health Science Center at Houston, Houston, TX, USA 8:30 a.m. Regression of Coronary Atherosclerosis in Diabetic Patients with High Intesity Statin Regimens: Insights From Saturn Brian Stegman, Leslie Cho, Steven Nissen, Mingyuan Shao, Christie Ballantyne, Phillip Barter, M. Chapman, Peter Libby, Joel Raichlen, Kiyoko Uno, Yu Kataoka, Rishi Puri, Stephen Nicholls, Cleveland Clinic Foundation, Cleveland, OH, USA 8:45 a.m. Optimal Grafting Strategy for Multivessel Coronary Artery Bypass Surgery Robert Tranbaugh, Thomas Schwann, Daniel Swistel, Kamellia Dimitrova, Laila Al‐Shaar, Darryl Hoffman, Charles Geller, Sandhya Balaram, Wilson Ko, Milo Engoren, Robert Habib, Beth Israel Medical Center, New York, NY, USA, American University of Beirut, Beirut, Lebanon 9:00 a.m. Impact of Cilostazol on Vascular Events in Patients Undergoing Coronary Stent Implantation with and without Prior Cerebral Infarction Hiroshi Ueda, Kojiro Yoshimura, Atsumichi Kido, Kenji Natsuyama, Seiji Matsuhisa, Koichiro Asawa, Naohiro Yoshida, Kazushige Yamaguchi, Yasushi Sasaki, Yukiko Kuga, Masahiro Yamasaki, Kazuya Ueda, Yasunori Nishida, Takai Hospital, Tenri, Japan 9:15 a.m. Same‐Day Discharge after Percutaneous Coronary Intervention: A Meta‐Analysis Kimberly Brayton, Vishal Patel, James de Lemos, Dharam Kumbhani, Stanford University, Stanford, CA, USA, UT Southwestern, Dallas, TX, USA CongenitalCardiologySolutions‐OralContributionsSession#904CongenitalCardiologySolutions:PediatricSaturday,March9,2013,8a.m.‐9:30a.m.North,Room121CMEHours:1.5/CNEHours:1.5 Co‐Chair: Gerard R. Martin Co‐Chair: Kathy J. Jenkins 8:00 a.m. A Randomized Clinical Trial of Regional Cerebral Perfusion versus Deep Hypothermic Circulatory Arrest: Five‐Year Follow‐Up for Neurodevelopmental Outcomes in Children with Functional Single Ventricle Melissa Smith‐Parrish, Sunkyung Yu, Janet Donohue, Richard Ohye, Edward Bove, Mary Best, Caren Goldberg, University of Michigan Health System, Ann Arbor, MI, USA 8:15 a.m. Gestational Age at Birth and Outcome after Neonatal Cardiac Surgery: An Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database

Sara Pasquali, John M. Costello, Xia He, Jeffrey P. Jacobs, Kevin Hill, David S. Cooper, Carl L. Backer, Marshall Jacobs, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA 8:30 a.m. Outcomes following Prolonged Extra Corporeal Membrane Oxygenation Support in Children with Cardiac Disease: Extracorporeal Life Support Organization Registry Study Laura Schoeneberg, Dean Merrill, Pratik Sandesara, Barbara Haney, Erica Molitor‐Kirsch, James O'Brien, Jr, Hongying Dai, Geetha Raghuveer, Children's Mercy Hospital, Kansas City, MO, USA, University of Missouri ‐ Kansas City School of Medicine, Kansas City, MO, USA 8:45 a.m. Vasoactive Inotropic Score (VIS) is Associated with Outcome after Infant Cardiac Surgery: A Report of the Pediatric Cardiac Critical Care Consortium (PC4) Michael Gaies, Howard Jeffries, Robert Niebler, Sara Pasquali, Janet E. Donohue, Sunkyung Yu, Ravi Thiagarajan, University of Michigan, Ann Arbor, MI, USA, Pediatric Cardiac Critical Care Consortium (PC4), Ann Arbor, MI, USA 9:00 a.m. Readmission within 30 Days of Pediatric Heart Surgery: Incidence, Risk Factors and Resource Utilization Samuel Paul Hanke, Catherine Krawczeski, Bradley Marino, Samir Shah, Edmund Berry, Eileen King, Lynn Darbie, James Cnota, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA 9:15 a.m. Valve Replacement with an Expandable Bioprosthetic Valve in Neonates and Infants Sitaram Emani, Frank Pigula, Christopher Baird, James Lock, Pedro del Nido, Boston Childrens Hospital, Boston, MA, USA HeartFailure‐MeettheExpertsSession#201BiomarkerGuidedManagementinHeartFailure:IsItReadyforPrimeTime?Saturday,March9,2013,8a.m.‐9:30a.m.West,Room3002CMEHours:1.5/CNEHours:1.5 Co‐Chair: Douglas L. Mann Panelist: Javed Butler Panelist: Mariell Jessup Panelist: Douglas L. Mann Panelist: Clyde W. Yancy 8:00 a.m. CASE PRESENTATION: An Elderly Advanced NYHA Class III Chronic Systolic HF Patient on Standard Evidence‐Based Medical Management Strategy and CRT‐D Seen in Outpatient Clinic with Worsening Heart Failure and BNP of 2500 pg/ml Akshay S. Desai, Boston, MA 8:00 a.m. Panel Discussion 8:00 a.m. Question and Answer



HeartFailure‐OralContributionsSession#905HeartFailurePathogenesisandTherapySaturday,March9,2013,8a.m.‐9:30a.m.South,Room102CMEHours:1.5/CNEHours:1.5 Co‐Chair: Thomas Force Co‐Chair: Joann Lindenfeld 8:00 a.m. Incidence and Clinical Characteristics of Takotsubo’s Cardiomyopathy among Patients with Aneurysmal Subarachnoid Hemorrhage: Retrospective Analysis of 2,276 Patients Thura T. Abd, Salim S. Hayek, Jeh‐Wei Cheng, Stamatios Lerakis, Emory University, Atlanta, GA, USA 8:15 a.m. Predictors of Urine Output and the Effects of Nesiritide in Acute Decompensated Heart Failure: Results from ASCEND‐HF Stephen S. Gottlieb, Adriaan Voors, Amanda Stebbins, Victor Hasselblad, Robert Califf, Christopher O'Connor, Randall Starling, Adrian Hernandez, University of Maryland, Baltimore, MD, USA 8:30 a.m. Treatment with Spironolactone Significantly Reduces 30‐Day Heart Failure Mortality and Rehospitalization Yang Xue, Dirk van Veldhuisen, Adriaan Voors, Paul Clopton, Tiny Jaarsma, Alan Maisel, VA San Diego Healthcare Center, San Diego, CA, USA, University of California San Diego, San Diego, CA, USA 8:45 a.m. Serial Measurement of Insulin‐Like Growth Factor Binding Protein 7 Predicts Chronic Heart Failure Outcomes and Ventricular Remodeling: Results from the ProBNP Outpatient Tailored Chronic Heart Failure Therapy (PROTECT) Study Shweta Motiwala, Anju Bhardwaj, Jackie Szymonifka, Arianna Belcher, Rory Weiner, Aaron Baggish, Hanna Gaggin, James Januzzi, Massachusetts General Hospital, Boston, MA, USA 9:00 a.m. Glycaemic Control and the Development of Heart Failure Helen Parry, Louise Donnelly, Natalie Van Zuydam, Andrew Morris, Douglas H. Elder, Alex SF Doney, Colin NA Palmer, Chim C. Lang, University of Dundee, Dundee, United Kingdom 9:15 a.m. Carbon Nanotubes Instruct Physiological Growth and Functionally Mature Syncytia: Non‐Genetic Engineering of Cardiac Myocytes Luisa Mestroni, Valentina Martinelli, Giada Cellot, Francesca M. Toma, Carlin Long, John Caldwell, Lorena Zentilin, Mauro Giacca, Antonio Turco, Maurizio Prato, Laura Ballerini, University of Colorado, Aurora, CO, USA, University of Trieste, Trieste, Italy HeartFailure‐OralContributionsSession#906ResynchronizationTherapyandRightVentricularFunctionSaturday,March9,2013,8a.m.‐9:30a.m.West,Room2006CMEHours:1.5/CNEHours:1.5 Co‐Chair: Marc J. Semigran Co‐Chair: William T. Abraham 8:00 a.m.

Totally Epicardial Cardiac Resynchronization Therapy Concomitantly with Coronary Artery Bypass Grafting in Patients with Ischemic Heart Failure: Three‐Year Results of RESCUE Study Alexander Romanov, Evgeny Pokushalov, Daria Prokhorova, Alexander Chernyavskiy, Vitaliy Shabanov, Kinga Goscinska‐Bis, Jaroslaw Bis, Andrzej Bochenek, Borut Gersak, Alexander Karaskov, State Research Institute of Circulation Pathology, Novosibirsk, Russian Federation 8:15 a.m. Reverse Remodeling with Cardiac Resynchronization Therapy Predicts Long‐Term Survival in Mildly Symptomatic Heart Failure Michael Robert Gold, Jean‐Claude Daubert, William Abraham, Stefano Ghio, Martin St. John Sutton, J Harrison Hudnall, Jeffrey Cerkvenik, Cecilia Linde, Medical University of South Carolina, Charleston, SC, USA 8:30 a.m. Novel Parameter of Electrical Activation Better Predicts Response to CRT‐D in Males than Baseline QRS Duration: A MADIT‐CRT Sub‐Study Valentina Kutyifa, Wojciech Zareba, Scott McNitt, Mehmet Aktas, Bela Merkely, Arthur Moss, Ilan Goldenberg, University of Rochester Medical Center, Heart Research Follow‐Up Program, Rochester, NY, USA 8:45 a.m. The Influence of Right Ventricular Pacing on Response to Biventricular Pacing: An Acute Pressure‐Volume Loop Study Lina Wu, Cornelis P. Allaart, Gerben J. de Roest, Matthijs L. Hendriks, Albert C. van Rossum, Carel C. de Cock, VU University Medical Center, Amsterdam, The Netherlands 9:00 a.m. Left Atrial Volume and the Benefit of Cardiac Resynchronization Therapy in MADIT‐CRT Rafael Kuperstein, Ilan Goldenberg, Arthur Moss, Scott Solomon, Scott McNitt, Robert Klempfner, The Leviev Heart Center, Sheba Medical Center, Ramat Gan, Israel, Tel Aviv University, Tel Aviv, Israel 9:15 a.m. The Relationship Between Tricuspid Annular Systolic Excursion and Pulmonary Arterial Systolic Pressure in Heart Failure: An Indicator of Cardiac Lenghh versus Force Relationship That Discloses Disease Severity and Prognosis Francesco Bandera, Ross Arena, Serenella Castelvecchio, Lorenzo Menicanti, Valentina Labate, Greta Generati, Eleonora Alfonzetti, Stefano Ghio, Pier Temporelli, Marco Guazzi, Heart Failure Unit, Cardiology, University of Milano, IRCCS Policlinico San Donato, San Donato Milanese, Milano, Italy Imaging‐MeettheExpertsSession#202BestPracticeofNuclearCardiologyinaMultimodalityArena:Patient‐CenteredSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3022CMEHours:1.5/CNEHours:1.5 Co‐Chair: Karthikeyan Ananthasubramaniam Co‐Chair: John J. Mahmarian Panelist: Timothy M. Bateman 8:00 a.m. CASE PRESENTATION: A Patient with New Onset Heart Failure and Severe LV Dysfunction: Focus on Multimodality Viability Imaging Indu G. Poornima 8:05 a.m. Panel Discussion



8:14 a.m. Question and Answer 8:23 a.m. CASE PRESENTATION: Integrating Function and Anatomy: SPECT and CTA ‐ How to Use and What First Benjamin J. W. Chow, Ottawa, Canada 8:28 a.m. Panel Discussion 8:36 a.m. Question and Answer 8:44 a.m. CASE PRESENTATION: Balanced Ischemia: SPECT versus PET Sharmila Dorbala, Boston, MA 8:49 a.m. Panel Discussion 8:57 a.m. Question and Answer 9:05 a.m. CASE PRESENTATION: How to Quantify Ischemic Burden in SPECT: Medical Therapy versus Revascularization Su Min Chang, Houston, TX 9:10 a.m. Panel Discussion 9:19 a.m. Question and Answer Imaging‐OralContributionsSession#907CardiacMRIinCAD:AcuteandChronicApplications,PrognosisandSafetySaturday,March9,2013,8a.m.‐9:30a.m.South,Room104CMEHours:1.5/CNEHours:1.5 Co‐Chair: Andrew E. Arai Co‐Chair: Phillip C. Yang 8:00 a.m. Cardiac Magnetic Resonance Imaging and Prognosis in ST‐Elevation Myocardial Infarction: Data from 1217 Patients Derived from Multicenter Studies Suzanne de Waha, Ingo Eitel, Georg Fuernau, Philipp Lurz, Jochen Woehrle, Henning Suenkel, Josefine Meissner, Sebastian Kerber, Bernward Lauer, Matthias Pauschinger, Ralf Birkemeyer, Christoph Axthelm, Rainer Zimmermann, Steffen Desch, Matthias Gutberlet, Gerhard Schuler, Holger Thiele, University of Leipzig ‐ Heart Center, Leipzig, Germany 8:15 a.m. Infarct Tissue Heterogeneity by Contrast‐Enhanced MRI is a Novel Predictor of Mortality in Patients with Chronic Coronary Artery Disease and Left Ventricular Dysfunction Siddique Abbasi, Eri Watanabe, Ravi Shah, Bobby Heydari, Tomas Neilan, Otavio Coelho‐Filho, Jiazuo Feng, Mike Steigner, Ron Blankstein, Michael Jerosch‐Herold, Raymond Kwong, Brigham and Women's Hospital, Boston, MA, USA 8:30 a.m.

Prognostic Value of Microvascular Obstruction and Infarct Size Measured by Cardiac Magnetic Resonance in Patients with ST‐Segment Elevation Myocardial Infarction: A Meta‐Analysis of Individual Patient Data Matthijs Van Kranenburg, Michael Magro, Suzanne de Waha, Holger Thiele, Vicente Bodi Peris, Alexandre Cochet, Gert Klug, Edwin Wu, Dan Atar, Peter Bernhardt, Ronak Delewi, Eric Boersma, Felix Zijlstra, Robert‐Jan van Geuns, Erasmus MC, Rotterdam, The Netherlands 8:45 a.m. Adenosine Perfusion Cardiac Magnetic Resonance Imaging for Risk Stratification in Patients with Stable Coronary Artery Disease: A Long‐Term Prospective Study in a Large Consecutive Cohort Dominik Buckert, Patricia Dewes, Thomas Walcher, Wolfgang Rottbauer, Peter Bernhardt, Internal Medicine II, Ulm, Germany 9:00 a.m. Prognostic Value of Stress Cardiac Magnetic Resonance Imaging in Patients with Known or Suspected Coronary Artery Disease: A Systematic Review and Meta‐Analysis Michael J. Lipinski, Courtney M. McVey, Jeffrey S. Berger, Christopher M. Kramer, Michael Salerno, University of Virginia Health System, Charlottesville, VA, USA, New York University, New York, NY, USA 9:15 a.m. Determining the Risks of Magnetic Resonance Imaging at 1.5 Tesla for Patients with Pacemakers and Implantable Cardioverter Defibrillators: The MagnaSafe Registry Robert J. Russo, Heather Costa, Ashish Kabra, Debra Doud, Seth Uretsky, Steven Wolff, Edward Martin, Christian Machado, Steven Higgins, Gail Tominaga, Todd Florin, Daniel Bloomgarden, Ulrika Birgersdotter‐Green, George Ponce, Raymond Schaerf, Rachel Lampert, Dipan Shah, Aysha Arshad, Jeffrey Anderson, Allison Tonkin, Andrew Rivard, Frazier Fyke, Robert Biederman, Scripps Clinic, La Jolla, CA, USA Imaging‐OralContributionsSession#908CoronaryCalciumandCardiacCTA:DiagnosisPrognosis,NewInsightsSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3010CMEHours:1.5/CNEHours:1.5 Co‐Chair: Christopher J. McGann Co‐Chair: Leslee J. Shaw 8:00 a.m. Year in Review Speaker James K. Min 8:15 a.m. Coronary Artery Disease in Young Adults: Insights from the Advanced Cardiovascular Imaging Consortium (ACIC) James L. Smith, Judith Boura, Gilbert Raff, Kavitha Chinnaiyan, Beaumont Health System, Royal Oak, MI, USA 8:30 a.m. Coronary Artery Calcium Score versus a Multiple Biomarker Approach for Coronary Heart Disease Risk Assessment: Multi‐Ethnic Study of Atherosclerosis Jamal S. Rana, Michael Pencina, Michael Blaha, Roger Blumenthal, Arthur Agatston, James K. Min, Ron Blankstein, Nathan D. Wong, Joao Lima, Leslee J. Shaw, Mathew J. Budoff, Mary Cushman, Daniel Berman, Khurram Nasir, Kaiser Permanente Northern California, Oakland, CA, USA, Baptist Health South Florida, Miami, FL, USA 8:45 a.m.



Eligibility for Polypill Therapy, Subclinical Atherosclerosis, and Cardiovascular Events ‐ National Implications for the Appropriate Use of Preventive Pharmacotherapy: Multi‐Ethnic Study of Atherosclerosis (MESA) Marcio Sommer Bittencourt, Michael Blaha, Ron Blankstein, Jose Vargas, Matthew Budoff, Arthur Agatston, Roger Blumenthal, Khurram Nasir, Brigham and Women's Hospital ‐ Harvard Medical School, Boston, MA, USA 9:00 a.m. Effect of Statin Treatment on Coronary Plaque Progression: A Serial CT Angiography Study Irfan Zeb, Dong Li, Jennifer Malpeso, Khurram Nasir, Christopher Dailing, Ferdinand Flores, Matthew Budoff, Los Angeles Biomedical Research Institute at Harbor‐UCLA Medical Center, Torrance, CA, USA 9:15 a.m. Can We Achieve a Benefit in All‐Cause Mortality by Routine Coronary Computed Tomographic Angiography in Asymptomatic Diabetic Patients? Byung‐Hee Hwang, Sungmin Lim, Ik Jun Choi, Mineok Chang, Jin Jin Kim, Donggyu Moon, Jae Gyung Kim, Eun ho Choo, Minkyu Kang, Byung‐Hee Hwang, Tae‐Hun Kim, Suk Min Seo, Yoon Seuk Koh, Pum Joon Kim, Kiyuk Chang, Wook Sung Chung, Ki‐Bae Seung, Catholic medical center, Seoul, South Korea Imaging‐OralContributionsSession#909NovelApplicationsofEchocardiography:ImplicationsforClinicalUseSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3006CMEHours:1.5/CNEHours:1.5 Co‐Chair: A. Jamil Tajik Co‐Chair: Patricia A. Pellikka 8:00 a.m. Relative Contribution of Afterload and Interstitial Tissue Fibrosis to Preoperative Longitudinal Function in Patients with Severe Aortic Stenosis: Implications for Postoperative Functional Recovery Julie Melchior, Sophie Pierard, Stephanie Seldrum, Caroline Bouzin, Christophe de Meester de Ravenstein, Frédéric Maes, Agnes Pasquet, Anne‐Catherine Pouleur, David Vancraeynest, Bernhard Gerber, Gebrine El Khoury, Sophie Minjauw, Jean‐Louis Vanoverschelde, Cliniques universitaires St Luc, Brussels, Belgium 8:15 a.m. Comparison of Transcatheter and Surgical Aortic Valve Replacement in Severe Aortic Stenosis: A Longitudinal Study of Echo Parameters in Cohort A of the PARTNER Trial Rebecca T. Hahn, Philippe Pibarot, William J. Stewart, Neil J. Weissman, Augusto Pichard, Howard C. Herrmann, Martin Leon, Susheel Kodali, Vinod Thourani, Lars Svensson, Pamela Douglas, Columbia University, New York, NY, USA 8:30 a.m. Attenuations in Tissue Doppler‐Derived Left Ventricular Systolic Velocity Predict an Amplified Risk of Lethal Arrhythmias in ICD Recipients Independently of Ejection Fraction Mohamad F. Barakat, Omar Chehab, Saj Hayat, Mihir Kelshiker, Hazel Turner, Karl Norrington, Klio Konstantinou, Zachary Whinnett, Michael Koa‐Wing, Charlotte Manisty, Ian Wright, Shahnaz Jamil‐Copley, Boon Lim, Nilesh Sutaria, Petros Nihoyannopoulos, David Lefroy, Jamil Mayet, Darrel P. Francis, David Wyn Davies, Nicholas Peters, Prapa Kanagaratnam, Darlington O. Okonko, International Centre for Circulatory Health, London, United Kingdom, Imperial College Healthcare, London, United Kingdom 8:45 a.m. Left Ventricular Global Longitudinal Strain Correlates to Diastolic Function and Reduced Exercise Capacity in Patients with Preserved Ejection Fraction

Nina E. Hasselberg, Kristina Haugaa, Sebastian I. Sarvari, Lars Gullestad, Arne K. Andreassen, Thor Edvardsen, Oslo University Hospital, Rikshospitalet, Oslo, Norway, University of Oslo, Oslo, Norway 9:00 a.m. Echo Derived Diastolic Function and Right Ventricular Systolic Pressure Correlate with Ventilatory Efficiency and Peak Oxygen Consumption in Patients with Dyspnea Jeremy Thaden, Robert McCully, Thomas Allison, Mayo Clinic, Rochester, MN, USA 9:15 a.m. Incremental Prognostic Value of Myocardial Perfusion Stress‐Echocardiography in Patients with Known Coronary Artery Disease Thomas Porter, Juefei Wu, Feng Xie, Stacey Therrien, Valentina Lorenzoni, Sabrina Molinaro, Claudio Reverberi, Nicola Gaibazzi, Parma University Hospital, Parma, Italy, University of Nebraska Medical Centre, Omaha, NE, USA Pericardial/MyocardialDisease/PulmonaryHypertension‐MeettheExpertsSession#203ChallengingCasesinHypertrophicCardiomyopathySaturday,March9,2013,8a.m.‐9:30a.m.West,Room3016CMEHours:1.5/CNEHours:1.5 Co‐Chair: Rick A. Nishimura 8:00 a.m. CASE PRESENTATION: The Mitral Valve Does Not Look Normal to Me Matthew W. Martinez 8:05 a.m. Panel Discussion 8:15 a.m. Question and Answer 8:30 a.m. CASE PRESENTATION: What Do I Do about This Gadolinium Hyper‐Enhancement? Martin S. Maron, Boston, MA 8:35 a.m. Panel Discussion 8:45 a.m. Question and Answer 9:00 a.m. CASE PRESENTATION: Is This HCM? David Owens, Seattle, WA 9:05 a.m. Panel Discussion 9:15 a.m. Question and Answer Prevention‐SymposiumSession#602HealthyPolicyandPrevention:DoesItWork?Saturday,March9,2013,8a.m.‐9:30a.m.North,Room122CMEHours:1.5/CNEHours:1.5 Co‐Chair: Harlan M. Krumholz



Co‐Chair: John S. Rumsfeld 8:00 a.m. Guidelines and Health Care Policy David C. Goff 8:18 a.m. Million Hearts Campaign Janet S. Wright, Baltimore, MD 8:36 a.m. Legislative Policy for CVD Prevenetion: Is It Effective? Peter W. Wilson, Atlanta, GA 8:54 a.m. System‐Based Prevention Eileen P. Pummer, Oakland, CA 9:12 a.m. Global Policy Measures of the Future Salim Yusuf, Hamilton, Canada QualityofCareandOutcomesAssessment‐MeettheExpertsSession#209GettingAccesstoData:WhereCanYoungInvestigatorsGetStartedinClinicalResearch?Saturday,March9,2013,8a.m.‐9:30a.m.West,Room3024CMEHours:1.5/CNEHours:1.5 Co‐Chair: Tracy Wang Panelist: Cook Nakela Panelist: Lesley Curtis Panelist: Gregg C. Fonarow Panelist: Frederick A. Masoudi 8:00 a.m. CASE PRESENTATION Robert W. Yeh, Boston, MA 8:00 a.m. Panel Discussion 8:00 a.m. Question and Answer SportsandExerciseCardiology‐SymposiumSession#603Let'sMove!ExerciseTraininginSpecialPopulationsSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3004CMEHours:1.5/CNEHours:1.5 Co‐Chair: Vera Bittner Co‐Chair: Jerome L. Fleg 8:00 a.m. Exercise Training for the Overweight and Obese Ross Arena 8:23 a.m. Exercise Training in Patients with Hypertrophic Cardiomyopathy Sharlene M. Day, Ann Arbor, MI 8:45 a.m. Don't Blow It: Exercise Training in the Patient with Aortic Disease Susan D. Housholder‐Hughes, Ann Arbor, MI

9:08 a.m. Exercise Training for Patients with Heart Failure and Ventricular Assist Devices Ileana L. Pina, Bronx, NY TCT@ACC‐i2:InnovationinIntervention‐SymposiumSession#2603AntiplateletManagementoftheSTEMIPatientSaturday,March9,2013,8a.m.‐9:30a.m.West,Room2001CMEHours:1.5/CNEHours:1.5 Co‐Chair: Erik Magnus Ohman Co‐Chair: Neal S. Kleiman 8:00 a.m. Prasugrel Gilles Montalescot 8:10 a.m. Ticagrelor Stefan K. James, Uppsala, Sweden 8:20 a.m. Cangrelor Robert A. Harrington, Stanford, CA 8:30 a.m. Discussion Antiplatelet and Antithombin Management of the STEMI Patient during and after Transfer 8:35 a.m. Case Presentation: Heparin and Clopidogrel Given at Outside Hospital 8:40 a.m. Antiplatelet and Antithombin Management of the STEMI Patient during and after Transfer Dominick J. Angiolillo, Jacksonville, FL 8:50 a.m. Discussion Debate: Can I Switch Oral Antiplatelet Agents after Hospital Discharge? 8:55 a.m. Consistent Therapy is Essential! Erik Magnus Ohman, Durham, NC 9:05 a.m. Switch to Clopidogrel, it is Only $13 per Month Roxana Mehran, New York, NY 9:15 a.m. Hold on! Just add Low‐dose Oral XA Therapy C. Michael Gibson, Boston, MA 9:25 a.m. Discussion



TCT@ACC‐i2:InnovationinIntervention‐SymposiumSession#2624InterventionalEchocardiography:AnEmergingImagingSubspecialtySaturday,March9,2013,8a.m.‐9:30a.m.West,Room2009CMEHours:0/CNEHours:1.5 Co‐Chair: Charles J. Bruce Co‐Chair: Rebecca T. Hahn 8:00 a.m. The Role of the Echocardiographer on Tte Structural Heart Disease Team Martin B. Leon 8:12 a.m. What the Interventionalist Needs to "See": How Imaging Improves Interventions Susheel Kodali, New York, NY 8:24 a.m. When the Echocardiographer Needs to "Intervene": Integrating Imaging into Interventions Sunil V. Mankad, Rochester, MN 8:36 a.m. The Role of the Anesthesiologist In Imaging for TAVR Massimiliano Meineri, Toronto, Canada 8:48 a.m. The Interventional Echocardiographer's Tools: When to Use TTE, TEE (2D and 3D) Charles J. Bruce, Rochester, MN 9:03 a.m. How and When to Use ICE for Structural and Valvular Interventions Howard C. Herrmann Philadelphia, PA 9:15 a.m. Discussion: Is Interventional Echocardiography a Viable New Field? TCT@ACC‐i2:InnovationinIntervention‐SymposiumSession#2632IntravascularImagingandPhysiology:GuidanceofStentImplantationSaturday,March9,2013,8a.m.‐9:30a.m.West,Room2002CMEHours:1.5/CNEHours:1.5 Co‐Chair: Massoud A. Leesar Co‐Chair: Akiko Maehara 8:00 a.m. IVUS Predictors of Stent Failure (Thrombosis and Restenosis) Gary S. Mintz 8:10 a.m. IVUS Guidance of Stent Implantation: How to Size, How to Optimize, and Evidence that IVUS Imaging Makes a Difference Myeong‐Ki Hong, Seoul, Korea, Republic of 8:20 a.m. OCT Predictors of Stent Failure (Thrombosis and Restenosis) Koji Kato, Boston, MA 8:30 a.m.

OCT Guidance of Stent Implantation: How to Size, How to Optimize, and Evidence tha tOCT Imaging Makes a Difference Francesco Prati, Rome, Italy 8:40 a.m. Is There a Role for Tissue Characterization ‐ VH‐IVUS, IB‐IVUS, or NIRS ‐ in Guiding and Optimizing Stent Implantation? James A. Goldstein, Royal Oak, MI 8:50 a.m. Is There a Role for FFR to Guide and Optime Stent Implantation? Allen Jeremias, Huntington, NY 9:00 a.m. Predicting Distal Embolization Using Grayscale IVUS, VH‐IVUS, IB‐IVUS, OCT, and NIRS (or even CTA) Bimmer E. Claessen, Amsterdam, Netherlands 9:10 a.m. Medicare Reimbursement, 30‐Day Readmissions Rates, and the Use of IVUS for PCI Luis Gruberg, Stony Brook, NY 9:20 a.m. How do FFR and IVUS (or Other Modalities) Fit into the Appropriate Use Criteria for Coronary Revascularization? Allen Jeremias, Huntington, NY TCT@ACC‐i2:InnovationinIntervention‐SymposiumSession#2655TAVR:TheImportanceofPatientEvaluationandSelectionSaturday,March9,2013,8a.m.‐9:30a.m.West,Room2005CMEHours:1.5/CNEHours:1.5 Co‐Chair: E. Murat Tuzcu Co‐Chair: Craig R. Smith 8:00 a.m. What Non‐operable Patients Should Not Undergo TAVR? Michael J. Mack 8:08 a.m. Question and Answer 8:11 a.m. Debate on High‐Risk Operable Patients: TAVR versus SAVR 8:14 a.m. Most Patients Should Undergo TAVR E. Murat Tuzcu, Cleveland, OH 8:22 a.m. Most Patients Should Undergo SAVR D. Craig Miller, Stanford, CA 8:30 a.m. Question and Answer 8:35 a.m. What is a Frail Patient? How to Evaluate and Use Frailty in the Clinical Decision Making Process for TAVR Candidates Philip Green, New York, NY 8:43 a.m. Question and Answer



8:46 a.m. How to Evaluate the Access and Determine the TAVR Approach Corrado Tamburino, Catania, Italy 8:54 a.m. Question and Answer 8:57 a.m. Multi‐Imaging Modality to Properly Evaluate Aortic Annulus Size ‐ Importance for Appropriate Valve Sizing on Clinical Outcomes Raj R. Makkar, Los Angeles, CA 9:05 a.m. Question and Answer 9:08 a.m. Are Some Patients More Appropriate for a Balloon‐Expandable versus Self‐Expandable Valve and Vice Versa? Alaide Chieffo, Milan, Italy 9:16 a.m. Question and Answer 9:19 a.m. How to Run a TAVR Program Elizabeth K. Walsh, Philadelphia, PA 9:27 a.m. Question and Answer TCT@ACC‐i2:InnovationinIntervention‐OralContributionsSession#2901LeftMainandBifurcationPCISaturday,March9,2013,8a.m.‐9:30a.m.West,Room2022CMEHours:1.5/CNEHours:1.5 8:00 a.m. State of the Art: Risk Stratification for Left Main PCI Davide Capodanno, Jacksonville, FL 8:15 a.m. Seven‐Year Clinical Outcomes of Unprotected Left Main Coronary Artery Stenting with Drug‐Eluting Stent and Bare‐Metal Stent Shunsuke Kubo, Kazushige Kadota, Seiji Habara, Takeshi Tada, Hiroyuki Tanaka, Yasushi Fuku, Harumi Katoh, Tsuyoshi Goto, Kazuaki Mitsudo, Kurashiki Central Hospital, Kurashiki, Japan 8:30 a.m. Comparison of Five Years Clinical Outcome of Drug‐Eluting Stent Implantation in High‐Angled (≥70°) Bifurcation and Lower‐Angled (≤70°) Bifurcation Lesion of Unprotected Left Main Coronary Arteries Sunao Nakamura, Shotaro Nakamura, Hisao Ogawa, Hans Yeo, Wasan Udayachalerm, Damras Tresukosol, Sudaratana Tansuphaswadikul, New Tokyo Hospital, Chiba, Japan 8:45 a.m. The Role of Female Sex in the Contemporary Treatment of the Left Main Coronary Artery Insights from the W‐ DELTA (Women‐ Drug Eluting stent for LefT main coronary Artery disease) Registry Gill Louise Buchanan, Alaide Chieffo, Emanuele Meliga, Seung‐Jung Park, Yoshinobu Onuma, Piera Capranzano, Marco Valgimigli, Sanda Jegere, Raj Makkar, Igor Palacios, Pawel Buszman, Imad Sheiban, Roxana Mehran, Christoph Naber, Ronan Margey, Arvind Agnihotri, Davide Capodanno, Martin Leon, Jean Fajadet, Marie Morice, Thierry Lefevre, Andrejs Erglis, Corrado Tamburino, Patrick Serruys, Antonio Colombo, San Raffaele Scientific Institute, Milan, Italy

9:00 a.m. Validation of Fractional Flow Reserve in Intermediate Left Main Coronary Artery Stenosis Jung‐Min Ahn, Seungmo Kang, Young‐Rak Cho, Gyung‐Min Park, Jong‐Young Lee, Won‐Jang Kim, Soo‐Jin Kang, Duk‐Woo Park, Seung‐Whan Lee, Young‐Hak Kim, Cheol Whan Lee, Seong‐Wook Park, Seung‐Jung Park, Asan Medical Center, Seoul, South Korea 9:15 a.m. Additional Side Branch Stent Placement in Patients with Long Side Branch Lesions Treated with a Dedicated Tryton Side Branch Stent Maik J. Grundeken, Solomon Asgedom, Peter Damman, Maciej Lesiak, Michael S. Norell, Eulogio Garcia, Armando Bethencourt, Pier Woudstra, Karel T. Koch, Marije M. Vis, Jose P. Henriques, Yoshinobu Onuma, David Foley, Antonio Bartorelli, Jan Tijssen, Pieter Stella, Robbert J. de Winter, Joanna Wykrzykowska, Academic Medical Center, Amsterdam, The Netherlands TCT@ACC‐i2:InnovationinIntervention‐OralContributionsSession#2902TranslationalScienceSaturday,March9,2013,8a.m.‐9:30a.m.West,Room2004CMEHours:1.5/CNEHours:1.5 8:00 a.m. Safety and Efficacy of Cardiac Cell Therapy: First Results of the MESS (Meta‐Analysis of Cardiac Stem Cell Studies) Database Including Individual Patient Data of 13 Randomized and 3 Cohort Studies Mariann Gyongyosi, Patricia Lemarchand, jerome roncalli, Ketil Lunde, Michal Tendera, Wojciech Wojakowski, Jozef Bartunek, Kai Wollert, Birgit Assmus, Andreas Zeiher, Jens kastrup, Martin Bergmann, Douwe Atsma, Evgeny Pokushalov, Jochen Woehrle, Slobodan Obradovic, J. Christer Sylven, Konstantinos Malliaras, Eduardo Marban, Gerald Maurer, Medical University of Vienna, Vienna, Austria 8:15 a.m. Does Transendocardial Injection of Mesenchymal Stem Cells Improve Myocardial Function Locally, or Globally: An Analysis from the POSEIDON Trial Viky Y. Suncion, Eduard Ghersin, Juan Pablo Zambrano, Vasileios Karantalis, Nicole S. Mandel, Katarina H. Nelson, Joel E. Fishman, Gary Gerstenblith, Darcy L. DiFede Velazquez, Elayne Breton, Ivonne H. Schulman, Kranthi Sitammagari, Peter V. Johnston, Jeffrey Brinker, Peter Altman, Muzammil Mushtaq, Barry Trachtenberg, Jose Da Silva, Ian K. McNiece, Albert C. Lardo, Richard T. George, Joshua M. Hare, Alan W. Heldman, University of Miami, Miami, FL, USA 8:30 a.m. Benefit of Atorvastatin Reload on Endothelial Progenitor Cells in Patients on Chronic Statin Treatment Undergoing PCI Elisabetta Ricottini, Rosalinda Madonna, Giuseppe Patti, Domenico Grieco, Alice Zoccoli, Barbara Stampachiacchiere, Andrea D'Ambrosio, Giuseppe Tonini, Raffaele De Caterina, Germano Di Sciascio, Department of Cardiovascular Sciences, Campus Bio‐Medico University of Rome, Rome, Italy, Institute of Cardiology, G. d'Annunzio University, Chieti, Italy 8:45 a.m. Sirolimus‐FKBP12.6 Impairs Endothelial Barrier Function through PKCalpha Activation and Disruption of the VE Cadherin‐p120 Catenin Interaction Anwer Habib, Vinit Karmali, Rohini Polavarapu, Hirokuni Akahori, Kim Pachura, Fumiyuki Otsuka, Frank Kolodgie, Renu Virmani, Aloke Finn, Emory University, Atlanta, GA, USA, CVPath Institute, Inc, Gaithersburg, MD, USA 9:00 a.m. Use of Ex Vivo Cryoimaging as an Adjuvant for Plaque Validation by Optical Coherence Tomography and for Characterization of Fibrous Cap Inflammation in Atherosclerotic Plaques



Ali Faramarzalian, David Prabhu, Ahmad Abdul‐Aziz, Daniel Chamie, Hirosada Yamamoto, Yusuke Fujino, Wei Wang, Nicholas Ziats, Andrew Rollins, David Wilson, Marco Costa, Hiram Bezerra, Harrington‐McLaughlin Heart and Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH, USA, Biomedical Engineering, Radiology, and Pathology, Case Western Reserve University, Cleveland, OH, USA 9:15 a.m. MKL1 C‐184>T and CYP3A5 A‐6986>G Polymorphisms Are Associated with Contrast Induced Acute Kidney Injury after PCI Bimmer E. Claessen, George Syros, Roxana Mehran, Elias Sanidas, Vasiliki Chantziara, Irine Apostolidou, Giora Weisz, Leroy Rabbani, Craig Hooper, George Dangas, Cardiovascular Research Foundation, new York, NY, USA, Academic Medical Center‐ University of Amsterdam, Amsterdam, The Netherlands VascularMedicine‐OralContributionsSession#911VascularMedicine:NewInsightsinArterialDiseaseSaturday,March9,2013,8a.m.‐9:30a.m.West,Room3005CMEHours:1.5/CNEHours:1.5 Co‐Chair: John P. Cooke Co‐Chair: Jeffrey W. Olin 8:00 a.m. Platelet‐Mimicking Multi‐Ligand Nanoparticles Inhibit Endothelial Cell Inflammation and Neointimal Restenosis Hao Xu, Emmanouil Brilakis, Kytai T. Nguyen, Subhash Banerjee, UT Southwestern Medical Center, Dallas, TX, USA, UT Arlington, Arlington, TX, USA 8:15 a.m. Flavonoid Administration Improves Arterial Wall Properties in Healthy Smokers Eleni Kokkou, Gerasimos Siasos, Dimitris Tousoulis, Evangelos Oikonomou, Maria Eleni Kollia, Alexios Verveniotis, Stamatios Kioufis, Nikolaos Gouliopoulos, Marina Zaromitidou, Panagiotis Tourikis, Konstantinos Zisimos, Georgios Marinos, Athanasios Papavassiliou, Christodoulos I Stefanadis, 1st Cardiology Department, University of Athens Medical School, “Hippokration” Hospital, Athens, Greece 8:30 a.m. Vorapaxar Reduces Peripheral Revascularization Regardless of the Number of Diseased Territories: Insights from the TRA2P‐TIMI 50 Trial Marc Bonaca, Mark Creager, Jeffrey Olin, Benjamin Scirica, Erin Bohula, Sabina Murphy, Eugene Braunwald, David Morrow, TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY, USA 8:45 a.m. Peripheral Arterial Disease Testing Prior to Amputation in Medicare Patients Sreekanth Vemulapalli, Melissa Greiner, William Jones, Manesh Patel, Adrian Hernandez, Lesley Curtis, Duke University, Durham, NC, USA, Duke Clinical Research Institute, Durham, NC, USA 9:00 a.m. Support for Standardization of Duplex Ultrasound Diagnostic Criteria for Internal Carotid Artery Stenosis: A Survey from the Intersocietal Accreditation Commission (IAC) Heather L. Gornik, Laurence Needleman, James Benenati, Phillip P. Bendick, Marge Hutchisson, Sandra Katanick, Amanda Naylor, Tammie Sloper, Michael Jaff, Cleveland Clinic, Cleveland, OH, USA, Intersocietal Accreditation Commission, Ellicott City, MD, USA 9:15 a.m.

Does the Presence of Accessory Renal Arteries Affect the Efficacy of Renal Denervation? Dani Id, Benjamin Kaltenbach, Stefan C. Bertog, Marius Hornung, Ilona Hofman, Horst Sievert, CardioVascular Center, Frankfurt, Germany LifelongLearning‐LifelongLearningSession#800ACCFStudySessionforMaintenanceofCertification:AmericanBoardofPediatrics(ABP)RecertificationMadeEasy‐‐2012PediatricCardiologySubspecialtySelf‐AssessmentSaturday,March9,2013,8a.m.‐10a.m.West,Room2018CMEHours:0/CNEHours:1.5 Co‐Chair: Karen K. Stout Panelist: Mark B. Lewin Panelist: Jeffrey A. Feinstein Panelist: Bryan C. Cannon SpecialTopics‐SpecialSessionSession#300ACC.13OpeningShowcaseandLate‐BreakingClinicalTrialsSaturday,March9,2013,8a.m.‐10a.m.South,EsplanadeBallroomCMEHours:2/CNEHours:2 8:00 a.m. Opening Video and National Anthem 8:04 a.m. Welcome, Introductions and Acknowledgements William A. Zoghbi, Houston, TX 8:10 a.m. Introduction of Keynote Lecturer William A. Zoghbi, Houston, TX 8:12 a.m. Simon Dack Lecture: From Cardiovascular Disease to Health: The Journey of the High‐Risk Plaque Valentin Fuster, New York, NY 8:35 a.m. ACC Presidential Address William A. Zoghbi, Houston, TX 9:00 a.m. Late‐Breaking Clinical Trial Presentations Co‐Chair: Panagiotis E. Vardas Co‐Chair: William A. Zoghbi Panelist: Donna Arnett Panelist: Christie M. Ballantyne 9:00 a.m. Final Results of Randomized Trial of Left Atrial Appendage Closure versus Warfarin for Stroke/Thromboembolic Prevention in Patients with Non‐Valvular Atrial Fibrillation (PREVAIL) David R. Holmes, Shephal Doshi, Saibal Kar, Jose Sanchez, Vijay Swarup, Brian Whisenant, Miguel Valderrabano, Kenneth Huber, Daniel Lustgarten, Vivek Reddy, Mayo Clinic, Rochester, MN, USA 9:20 a.m. Panel Discussion 9:30 a.m.



HPS2‐THRIVE: Randomized Comparison of Extended‐Release (ER) niacin/laropiprant 2g Daily versus Placebo in 25,673 Patients at High Risk of Occlusive Vascular Events Jane Margaret Armitage, HPS2‐THRIVE Collaborative Group, Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom 9:50 a.m. Panel Discussion ChronicCAD/StableIschemicHeartDisease‐SymposiumSession#604PharmacologyProgramII‐DepressionandtheCardiacPatient:WhattheCardiacCareTeamShouldKnowtoSafelyPrescribeAnti‐DepressantsSaturday,March9,2013,8:30a.m.‐9:30a.m.West,Room2010CMEHours:1/CNEHours:1 Co‐Chair: Joseph S. Alpert Co‐Chair: David Parra 8:30 a.m. Depression and the Cardiac Patient: What the Cardiac Care Team Should Know to Safely Prescribe Anti‐Depressants Rhonda M. Cooper‐DeHoff Panelist: Eileen M. Handberg Panelist: Kerry Pickworth Panelist: W. Victor Vieweg ValvularHeartDisease‐Self‐DirectedLearningSessionSession#1500HeartSongsatACC.13:ASelf‐PacedMultimediaLearningExperienceSaturday,March9,2013,9a.m.‐5p.m.West,Room2000CMEHours:1/CNEHours:1 Co‐Chair: Michael J. Barrett Co‐Chair: Patrick Kleaveland Co‐Chair: Bruce Silverberg Co‐Chair: Christina Dunbar Co‐Chair: Bilal Ayub Co‐Chair: Matthew W. Martinez AcuteCoronarySyndromes‐PosterContributionsSession#1126MIComplications:Shock,ArrestandCardiacRuptureSaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 173 ‐ Gender Differences in Patients with Out‐of‐Hospital Cardiac Arrest over a 20‐Year Period: A Middle Eastern Perspective Abdulrahman Arabi, Ashfaq Patel, Jassim Alsuwaidi, Rajvir Singh, Hajar Albinali, Hamad Medical Corporation, Doha, Qatar 174 ‐ Prevalence, Clinical Profile, Management and Outcomes in Patients with STEMI and Out‐of‐Hospital Cardiac Arrest: Insight from a 20‐Year Registry in the State of Qatar Abdulrahman Arabi, Ashfaq Patel, Jassim Alsuwaidi, Hakam Alzaeem, Hajar Albinali, Rajvir Singh, Hamad Medical Corporation, Doha, Qatar 175 ‐ Ethnic Differences in Patients with Out‐of‐Hospital Cardiac Arrest: Insight from a 20‐Year Registry in the State Of Qatar Abdulrahman Arabi, Ashfaq Patel, Jassim Alsuwaidi, Rajvir Singh, Hajar Albinali, Hamad Medical Corporation, Doha, Qatar

176 ‐ Frequency, Treatment and Impact of Pre‐Hospital Cardiac Arrest among Patients with STEMI: A Report from the ACTION Registry®‐GWTG™ and Mission:Lifeline Michael C. Kontos, Benjamin Scirica, Matthew Dupree, Monique L. Anderson, Debra B. Diercks, Daniel Munoz, James Jollis, Matthew Roe, Virginia Commonwealth University, Richmond, VA, USA 177 ‐ Level 1 Shock Team‐Early Experience in EMCO Use as a Rescue Device in Cardiac Arrest from STEMI in the Cardiac Catheterization Laboratory Michael R. Mooney, David Hildebrandt, David Feldman, Benjamin Sun, Dirck Rilla, Yale Wang, Ivan Chavez, M. Nicholas Burke, Timothy Henry, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN, USA 178 ‐ Over 20‐Year Trend of In‐Hospital Mortalityin Patientswith Cardiogenic Shock Using Percutaneous Extracorporeal Membrane Oxygenation: Comparison between ACS and Non‐ACS Patients Manabu Matsumoto, Satoshi Yasuda, Takafumi Yamane, Taichi Adachi, Tadayoshi Miyagi, Toshiyuki Nagai, Masashi Fujino, Yasuhide Asaumi, Reon Kumasaka, Tetsuo Arakawa, Jun‐ichi Kotani, Hiroki Sakamoto, Teruo Noguchi, Yoichi Goto, Hiroyuki Yokoyama, Toshihisa Anzai, Wataru Shimizu, Masaharu Ishihara, Takeshi Nakatani, Junjiro Kobayashi, Hisao Ogawa, National Cerebral and Cardiovascular Center, Osaka Suita, Japan 179 ‐ Long‐Term Clinical Follow‐Up in Patients with Acute Myocardial Infarction Complicated by Cardiogenic Shock Young Keun Ahn, Jong Hyun Yoo, Myung Ho Jeong, Chonnam National University Hospital, Gwangju, South Korea 180 ‐ The Residual SYNTAX Score for Mortality Risk Assessment in Acute Coronary Syndrome with Cardiogenic Shock Hidenori Adachi, Yoshinori Yasuoka, Kiyoshi Kume, Susumu Hattori, Yoshiki Noda, Ryo Araki, Ryo Matsutera, Motohiro Kosugi, Yasuaki Kohama, Tetsufumi Nakashima, Tatsuya Sasaki, Osaka Minami Medical Center, Osaka, Japan 181 ‐ Osteoprotegerin in Acute Myocardial Infarction Complicated by Cardiogenic Shock: A Biomarker Substudy of the IABP‐SHOCK II‐Trial Georg Friedrich Fuernau, Christian Poenisch, Ingo Eitel, Steffen Desch, Suzanne De Waha, Gerhard Schuler, Volker Adams, Karl Werdan, Uwe Zeymer, Holger Thiele, University of Leipzig ‐ Heart Center, Leipzig, Germany 182 ‐ Long‐Term Clinical Outcome in Patients with Acute Myocardial Infarction Complicating Cardiogenic Shock: Insight from the CREDO‐Kyoto a.m.I Registry Hiroki Shiomi, Takeshi Morimoto, Yutaka Furukawa, Yoshihisa Nakagawa, Takeshi Kimura, The CREDO‐Kyoto a.m.I Registry Investigators, Kyoto University Graduate School of Medicine, Kyoto, Japan 183 ‐ Changing Incidence of Cardiac Rupture and Its Determinants in Patients with Acute Myocardial Infarction: Results from 5,694 Patients Database over 35 Years Satoshi Honda, Yasuhide Asaumi, Masashi Fujino, Takafumi Yamane, Reon Kumasaka, Toshiyuki Nagai, Taichi Adachi, Tadayoshi Miyagi, Tetsuo Arakawa, Michio Nakanishi, Hiroki Sakamoto, Junichi Kotani, Teruo Noguchi, Yoichi Goto, Toshihisa Anzai, Wataru Shimizu, Masaharu Ishihara, Hisao Ogawa, Satoshi Yasuda, National Cerebral and Cardiovascular Center, Suita, Japan 194 ‐ Antiplatelet Action of Clopidogrel and Prasugrel in Patients with Acute Myocardial Infarction Complicated by Cardiogenic Shock Martin Orban, Isabell Bernlochner, Mathias Orban, Katharina Mayer, Martin Hadamitzky, Siegmund Braun, Joerg Hausleiter, Karl‐Ludwig Laugwitz, Klaus Tiroch, Steffen Massberg, Julinda Mehilli, Dirk Sibbing, Adnan Kastrati, Department of Medicine I, Klinikum Großhadern, University of Munich, Munich, Germany, Deutsches Herzzentrum München & 1. Medizinische Klinik, Technische Universität, Munich, Germany



AcuteCoronarySyndromes‐PosterContributionsSession#1127AcuteCoronarySyndromes:BasicISaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 188 ‐ Inositol Hexakisphosphate Kinases' (ip6ks) Selective Inhibition Enhances Mesenchymal Stem Cells Engraftment and Improves Therapeutic Efficacy for Myocardial Infarction Feng Cao, Zheng Zhang, Dongdong Sun, Haichang Wang, Xijing Hospital, Xi an, People's Republic of China 189 ‐ Elevated CD14++CD16‐ Monocyte Count Is a Risk Factor for Coronary Artery Disease Jin‐Sok Yu, Chul‐Soo Park, Yun‐Seok Choi, Ju‐Youn Kim, Woo‐Baek Chung, Man‐Young Lee, Yong‐Seok Oh, Ho‐Joong Youn, Wook‐Sung Chung, Sang‐Hyun Ihm, Yeouido St. Mary’s Hospital, SEOUL, South Korea 190 ‐ Mitochondrial Na+/Ca2+ Exchanger Inhibition during Reperfusion Exhibits Potential Cardioprotective Effect, in a Porcine Ischemia‐Reperfusion Model John Terrovitis, Stefania Sventzouri, Lampros Katsaros, Vasilios Sousonis, Nickolaos Michelinakis, Chris Kapelios, Titika Sfakianaki, Argyrios Ntalianis, Apostolos Papalois, John Nanas, University of Athens, 3rd Dept. of Cardiology, Athens, Greece 191 ‐ Acute Hypoxia‐Inducible Factor EglN1 Inactivation Protects against Ischemia‐Reperfusion Injury by Regulation of Glucose Oxidation and Reactive Oxygen Species Generation Alan Baik, Ben Olenchock, Javid Moslehi, William G. Kaelin, Jr., Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA, Dana‐Farber Cancer Institute, Boston, MA, USA 192 ‐ Ischemic Preconditioning and Inhibition of the Malate‐Aspartate Shuttle Preserves Mitochondrial Respiration and Decreases ROS Production in the Isolated Rat Heart Nichlas Riise Jespersen, Takashi Yokota, Kim Nielsen, Nicolaj B. Støttrup, Jonas Povlsen, Flemming Dela, Hans Erik Bøtker, Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark, Department of Biomedical Sciences, Panum Institute, Copenhagen, Denmark 193 ‐ Impact of Platelet Transfusion on Platelet Activation and Aggregation in Cardiac Surgery Patients Receiving Aspirin and P2Y12 Receptor Antagonists Stephen A. O'Connor, Rejane Martin, Julien Amour, Jeremie Abtan, Mathieu Kerneis, Johanne SILVAIN, Pascal Leprince, Gilles Montalescot, Jean‐Philippe Collet, Pitié Salpêtrière Hospital, Paris, France AcuteCoronarySyndromes‐ModeratedPosterContributionsSession#1128MBodySizeandMIRisk:IsBiggerBetter?Saturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 196 ‐ Obesity in Young Adult Men and Risk of Type II Diabetes, Cardiovascular Morbidity, or Death before 55 Years of Age: A Danish 33‐Year Follow‐Up Study Morten Schmidt, Sigrun A. Johannesdottir, Stanley Lemeshow, Timothy Lash, Sinna P. Ulrichsen, Hans Erik Boetker, Henrik Toft Soerensen, Aarhus University Hospital, Aarhus, Denmark, The Ohio State University, Columbus, OH, USA 197 ‐ Association of Body Mass Index with Risks of Myocardial Infarction and Ischemic Stroke in Young Women: A Nationwide Study Michelle Dalgas Schmiegelow, Charlotte Andersson, Kober Lars, Soren Skott Andersen, Jonas B. Olesen, Thomas B. Jensen, Aziza Azimi, Christian Torp‐

Pedersen, Department of Cardiology, Gentofte Hospital, Denmark, Hellerup, Denmark 198 ‐ Obesity and Prognosis in Patients with Acute Myocardial Infarction Gauravkumar Patel, Raef Hajjali, Allegheny General Hospital, Pittsburgh, PA, USA 199 ‐ Young Obese Men Are Characterized by Multiple Coronary Risk Factors, a Larger Infarct Size, and Impaired Myocardial Reperfusion in Patients with Anterior Acute Myocardial Infarction Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Yoshio Tahara, Satoshi Umemura, Kazuo Kimura, Yokohama City University Medical Center, Yokohama, Jordan 200 ‐ Obesity Is Associated with Lower Mortality following Acute Coronary Syndromes: A Meta‐Analysis Sachil Shah, Nicholas Hartmann, Mauricio Cohen, Hermes Florez, Ana Palacio, Tamariz Leonardo, University of Miami Miller School of Medicine Regional Campus, Atlantis, FL, USA, University of Miami Miller School of Medicine, Miami, FL, USA 201 ‐ The Obesity Paradox: Do Obese Patients Experience a Difference in Time to Reperfusion? Abhishek Jaiswal, Saket Girotra, Azriel Avezbadalov, Mahjabeen Rashid, Chong Park, Todd Kerwin, New York Hospital Queens, Flushing, NY, USA AcuteCoronarySyndromes‐PosterContributionsSession#1129ACSTherapy:AntiplateletAgentsSaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 184 ‐ Comparison of 600mg versus 300mg Loading Dose of Clopidogrel for Patients with STEMI: A Meta‐Analysis Ankur Vyas, Ramzi El Accaoui, Amy Blevins, Wassef Karrowni, University of Iowa Hospitals & Clinics, Iowa City, IA, USA 185 ‐ Clopidogrel Reloading in Patients with Acute Coronary Syndrome Undergoing PCI on Chronic Clopidogrel Therapy: Results of the Armyda‐8 Reload‐ACS (Antiplatelet Therapy for Reduction of Myocardial Damage during Angioplasty) Randomized Trial Elisabetta Ricottini, Giuseppe Patti, Vincenzo Vizzi, Vincenzo Pasceri, Fabio Mangiacapra, Giuseppe Colonna, Antonio Montinaro, Ilaria Cavallari, Andrea D'Ambrosio, Emanuele Barbato, William Wijns, Germano Di Sciascio, Department of Cardiovascular Sciences, Campus Bio‐Medico University of Rome, Rome, Italy 186 ‐ The Association between Concomitant Proton‐Pump Inhibitor Use and Clinical Outcomes in Patients with Acute Coronary Syndromes Treated with Prasugrel versus Clopidogrel and Managed without Revascularization: Insights from the TRILOGY ACS Study Jose C. Nicolau, Deepak Bhatt, Matthew Roe, Benjamin Neely, Ramon Corbalan, Jose Leiva‐Pons, Felipe Martinez, Shaun Goodman, Eileen Brown, Freek Verheugt, Paul Armstrong, Harvey White, Keith Fox, Dorairaj Prabhakaran, E. Magnus Ohman, Duke Clinical Research Institute, Durham, NC, USA, Heart Institute (InCor) ‐ University of Sao Paulo Medical School, Sao Paulo, Brazil 187 ‐ Correlation between Response to Prasugrel and Levels of Reticulated Platelets in Patients with STEMI Leor Perl, Eldad Rechavia, Pablo Codner, Alon Eisen, Tamir Bental, Katia Orvin, Alex Battler, Ran Kornowski, Eli Lev, Rabin Medical Center, Petach Tikva, Israel 202 ‐ Outcomes of Anti‐Platelet Therapy for ACS And Non‐ACS Patients Directed by Post‐PCI Platelet Function Testing in a Real World Setting



Elad Asher, Perry Anarado, Myttle Mayuga, Martin Bradley, Ka Chun Alan Chan, Isidore Okere, Darwin Jeyaraj, Daniel Simon, Tom Lassar, Harrington Heart & Vascular Institute, Cleveland, OH, USA 203 ‐ In‐Hospital Switching of P2Y12 Inhibitor in Real‐Life Patients with Acute Coronary Syndrome: Insights from the GReek AntiPlatElet (GRAPE) Registry Dimitrios Alexopoulos, Ioanna Xanthopoulou, Evropi Tsoni, Ioannis Ntalas, Spyridon Deftereos, George Sitafidis, Periklis Davlouros, Vlassis Pyrgakis, Ioannis Goudevenos, Filippos Triposkiadis, Patras University Hospital, Patras, Greece, General Hospital “G. Gennimatas”, Athens, Greece 204 ‐ Contraindications for P2Y12 Inhibitors in Real‐Life Patients with Acute Coronary Syndrome: Insights From the GReek AntiPlatElet (GRAPE) Registry Dimitrios Alexopoulos, Ioanna Xanthopoulou, Argyro Siapika, Spyridon Deftereos, George Sitafidis, Ioannis Goudevenos, Filippos Triposkiadis, Vlassis Pyrgakis, Ioannis Kanakakis, Periklis Davlouros, Patras University Hospital, Patras, Greece, Larissa University Hospital, Larissa, Greece 205 ‐ Antithrombotic Management of Acute Coronary Syndrome in Patients with Atrial Fibrillation in the Intermountain Heart Collaborative Study Viet T. Le, Stacey Knight, Winslow Klaskala, Scott C. Woller, Benjamin Horne, Thomas Bunch, Roger Mills, J. Muhlestein, Intermountain Medical Center, Murray, UT, USA, University of Utah, Salt Lake City, UT, USA AcuteCoronarySyndromes‐PosterContributionsSession#1130Stress,CoronarySpasmanda.m.I:LessonsfromJapan,NewOrleans,GreeceSaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 195 ‐ The Impact of Northeast Japan Earthquake on Acute Myocardial Infarction and Heart Failure Nobuyuki Kuroiwa, Shigeru Fukuzawa, Shinichi Okino, Funabashi Municipal Medical Center, Division of Cardiology, Heart and Vascular Institute, Funabashi, Japan 206 ‐ Increase in the Incidence of Acute Coronary Syndrome after the 2011 East Japan Natural Disaster: Concordance with Sequential Quake Shocks Masanobu Niiyama, Fumitaka Tanaka, Kenyu Sato, Toshiyuki Onoda, Tomohiro Takahashi, Toshie Segawa, Miho Honma, Motoyuki Nakamura, Northern Iwate Heart Disease Registry Consortium, Iwate Med Univ, Morioka,Iwate, Japan 207 ‐ Socioeconomic Crisis and Incidence of Acute Myocardial Infarction in Messinia, Greece Emmanouil Makaris, George Michas, Renata Micha, Ioannis Pisimisis, Ilias Tsichlis, Dionysis Svoronos, Charalampos Panotopoulos, Dimitrios Gkotsis, George Koudounis, Spyridon Zompolos, General Hospital of Kalamata, Kalamata, Greece, Greece 208 ‐ Alteration in the Chronobiology of Onset of Acute Myocardial Infarction in New Orleans Residents following Hurricane Katrina Matthew N. Peters, Morgan J. Katz, John C. Moscona, Mohi E. Alkadri, Rashad K. Syed, Thomas A. Turnage, Vikram S. Nijjar, Mohannad B. Bisharat, Patrice Delafontaine, Anand M. Irimpen, Tulane University Health Sciences Center, New Orleans, LA, USA, New Orleans Veterans Affairs Medical Center, New Orleans, LA, USA 209 ‐ Insights from a Large Prospective Registry of Patients with Stress Cardiomyopathy Jacqueline Bradley, Archana Rajdev, Amit Dande, Mark Warshofsky, Danbury Hospital, Danbury, CT, USA 210 ‐ Thrombolysis in Myocardial Infarction Frame Count in Takotsubo Cardiomyopathy

Nauman Khalid, Ibraiz Iqbal, Sohail Ikram, University of Louisville School of Medicine, Louisville, KY, USA 211 ‐ Importance of Coronary Angiography in the Diagnosis of Takotsubo Cardiomyopathy Raef H. Hajjali, Amy B. Schuett, Gregory Suero, Benjamin Susco, Allegheny General Hospital, Pittsburgh, PA, USA 212 ‐ Takotsubo Cardiomyopathy May Be More Common than Previously Reported in Postmenopausal Women Presenting as ACS Fridolin T. Sy, Jagroop Basraon, Hong Zheng, Manminder Singh, John Ambrose, UCSF Fresno, Fresno, CA, USA 213 ‐ Clinical Features and Prognosis in Patients with Coronary Spasm‐Induced Non‐ST‐segment Elevation ACS Naoki Nakayama, Koichi Kaikita, Koji Sato, Eiji Horio, Kazuo Kimura, Hisao Ogawa, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan 214 ‐ Seasonality and Daily Weather Conditions in Relation to Myocardial Infarction in Northeastern Pennsylvania Pranjal Kumar Boruah, Imdad Ahmed, Joseph Snedeker, Stephen Voyce, Wright Center for Graduate Medical Education, Scranton, PA, USA 215 ‐ Acute Myocardial Infarction and In‐Hospital Mortality after Carbon Monoxide Poisoning: An Analysis of the Nationwide Inpatient Sample 2002‐2010 Marjan Ul Mujib, Sahil Khera, Dhaval Kolte, Chandrasekar Palaniswamy, Jalaj Garg, Wilbert S. Aronow, New York Medical College, Valhalla, NY, USA 216 ‐ Fine Particle Air Pollution Is a Potential Trigger for STEMI but Not Non‐STEMI Blake Gardner, David Q. Rich, Suresh Kulandhaisamy, Michael Topf, Kelly Thevenet‐Morisson, Cathleen Kane, Mark Frampton, Wojciech Zareba, Mark Utell, Frederick Ling, University of Rochester Medical Center, Rochester, NY, USA Arrhythmias‐PosterContributionsSession#1104VentricularArrhythmiasinCardiomyopathySaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 27 ‐ B‐type Natriuretic Peptide May Promote Arrhythmia In Heart Failure Through Inhibiting Transient Outward Potassium Current JUNPING SUN, Yutao Xi, Geru Wu, Nancy Cheng, Shahrzad Abbasi, MacArthur A. Elayda, Suwei Wang, Reynolds M. Delgado, Jie Cheng, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, TX, USA, Section of Cardiology, University of Texas Health Science Center, Houston, TX, USA 28 ‐ Usefulness Of Tpeak‐Tend Interval To Distinguish Arrhythmogenic Right Ventricular Cardiomyopathy From Idiopathic Right Ventricular Outflow Tachycardia Kivanc Yalin, Ebru Golcuk, Ahmet Kaya Bilge, Kamil Adalet, Istanbul University, Istanbul Faculty of Medicine, Department of Cardiology, Istanbul, Turkey 29 ‐ The Risk Of Cardiac Events And QRS Fragmentation In The Patients With Arrhythmogenic Right Ventricular Cardiomyopathy. Grzegorz Pietrasik, Frank Marcus, Wojciech Zareba, Division of Cardiovascular Medicine, Department of Medicine, University at Buffalo, Buffalo, NY, USA, Heart Research Follow‐Up Program, University of Rochester Medical Center, Rochester, NY, USA 30 ‐ Heart Transplantations in the Nordic Arrhythmogenic Right Ventricular Cardiomyopathy Registry



Pyotr G. Platonov, Thomas Gilljam, Anders G. Holst, Kristina H. Haugaa, Thor Edvardsen, Rasmus Borgquist, Ole Eschen, Jim Hansen, Henning Bundgaard, Jesper H. Svendsen, Lund University, Lund, Sweden, Rigshospitalet ‐ Copenhagen University Hospital, Copenhagen, Denmark 31 ‐ Patients with Non‐Ischemic Cardiomyopathy and Syncope are at High Risk of Ventricular Arrhythmias in Follow‐up Yutthapong Temtanakitpaisan, David Kopelman, Ahsanuddin Ahmad, N. A. Estes, Mark Link, Tufts Medical Center, Boston, MA, USA 32 ‐ Predictors of Arrhythmic Events in Non‐Ischemic Dilated Cardiomyopathy: A Meta‐Analysis Taral Patel, Haris Subacius, Ryan Cunnane, Jeffrey Goldberger, Northwestern University, Chicago, IL, USA 33 ‐ T‐Wave Alternans (TWA) Is Associated with Cardiovascular Mortality and NSVT in the MERLIN‐TIMI 36 Trial of Ranolazine versus Placebo in Patients with Non‐ST Segment Elevation Acute Coronary Syndrome Benjamin Scirica, Tuomo Nieminen, Jose RM Pegler, Caio Tavares, Vitor PF Pagotto, Alexandre F. Kanas, Marcel F. Sobrado, Bruce Nearing, Ji Cho, David Morrow, Luiz Belardinelli, Richard Verrier, Harvard Medical School, Boston, MA, USA, Helsinki University Central Hospital, Helsinki, Finland 34 ‐ Circadian Variation of ICD‐Shocks in Patients with Chronic Heart Failure: the Impact of Cheyne‐Stokes Respiration and Obstructive Sleep Apnea Thomas Bitter, Natalie Prib, Andrea Zwenke, Christian Prinz, Zisis Dimitriadis, Dieter Horstkotte, Olaf Oldenburg, Department of Cardiology, Heart and Diabetes Center North Rhine‐Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany 35 ‐ Catheter Ablation of Hemodynamically Unstable Ventricular Tachycardia with Mechanical Circulatory Support Fei Lu, Peter Eckman, Kenneth Liao, Ioanna Apostolidou, Ranjit John, Taibo Chen, Philip Meyer, Gladwin Das, David Benditt, Daniel Garry, University of Minneasota, Minneapolis, MN, USA Arrhythmias‐ModeratedPosterContributionsSession#1105MArrhythmias:AtrialFibrillationClinicalMechanismsSaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 36 ‐ Accuracy of Patient Perceived Atrial Fibrillation Measurements: A Comparative Analysis of Objective Monitor Data and Subjective Patient Reporting Roja S. Garimella, Eugene H. Chung, J. Paul Mounsey, Jennifer Schwartz, Irion Pursell, Anil Gehi, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, William G. Enloe Magnet High School, Raleigh, NC, USA 37 ‐ Left Atrial Sphericity: A New Method to Assess Left Atrial Remodeling. Impact on the Outcome of Pulmonary Vein Isolation Felipe Bisbal, Esther Guiu, Naiara Calvo, Roger Borràs, Elena Arbelo, Bárbara Vidal, David Marin, Jose M. Tolosana, Antonio Berruezo, Teresa M. Caralt, Marta Sitges, Josep Brugada, Lluís Mont, Hospital Clínic, Barcelona, Spain, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain 38 ‐ Digoxin and Risk of Death in Adults with Atrial Fibrillation: The ATRIA‐CVRN Study James V. Freeman, Kristi Reynolds, Margaret Fang, Natalia Udaltsova, Anthony Steimle, Daniel Singer, Alan Go, Stanford University School of Medicine, Stanford, CA, USA, Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA 39 ‐ Symptomatic and Asymptomatic Children with Ventricular Preexcitation: Same Risk for Sudden Death Corrado Di Mambro, Mario Salvatore Russo, Daniela Righi, Massimo Stefano Silvetti, Silvia Placidi, Rosalinda Palmieri, Lorenzo Santucci, Monica Prosperi,

Fabrizio Gimigliano, Fabrizio Drago, Ospedale Pediatrico Bambino Gesu, Palidoro (Roma), Italy 40 ‐ Vernakalant Facilitated Electrical Cardioversion: A Randomized, Open Label Pilot Study Comparing Intravenous Vernakalant and Amiodarone for Drug‐Enhanced Electrical Cardioversion of Cardioversion‐Resistant Atrial Fibrillation Andreas Bollmann, Silke John, Andreas Muessigbrodt, Borislav Dinov, Sergio Richter, Gerhard Hindricks, Heart Center Leipzig, Leipzig, Germany 41 ‐ Ablation of Paroxysmal and Persistent Atrial Fibrillation: Long‐Term Recurrence Rates via Continuous Subcutaneous Monitoring Evgeny Pokushalov, Alexander Romanov, Sergey Artyomenko, Alexey Turov, Natalia Shirokova, Alexander Karaskov, Suneet Mittal, Jonathan S. Steinberg, State Research Institute of Circulation Pathology, Novosibirsk, Russian Federation, The Valley Health System and Columbia University College of Physicians and Surgeons, New York, NY, USA ACC Poster Moderator: Suneet Mittal Arrhythmias‐PosterContributionsSession#1106Arrhythmias:BasicScienceandAtrialFibrillationSaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 42 ‐ Antiarrhythmic Effect of Corticosteroid by Suppressing Inflammation and Ca2+/Calmodulin‐Dependent Protein Kinase II Activation in Autoimmune Myocarditis Boyoung Joung, Hyelim Park, Hui‐Nam Pak, Moon‐Hyoung Lee, Yonsei University College of Medicine, Seoul, South Korea 43 ‐ Multi‐Scale Modeling Conduction of Stem Cell Graft and Host Cardiac Myocytes Derived from Dilated Cardiomyopathy Jin Yu, Yu Feng, Fan Guo, Haichang Wang, Lize Xiong, Dept.of Cardiovascular Medicine, Xijing Hospital, Xi An, People's Republic of China 44 ‐ Racial Patterns In Catheter Ablation For Atrial Fibrillation And Atrial Flutter Alexis P. Rodriguez, Leonardo Tamariz, Ana Palacio, Hua Li, Robert J. Myerburg, University of Miami Miller School of Medicine, Miami, FL, USA 45 ‐ Real‐world Outcomes for Dronedarone Initiators Compared to Other Antiarrhythmic Agents in the Treatment of Atrial Fibrillation in a Large United States Population Earl Goehring, Rhonda Bohn, John Pezzullo, Judith Jones, The Degge Group, Ltd., Arlington, VA, USA 46 ‐ Influence of Zoledronic Acid on Atrial Electrophysiological Parameters Associated With Risk of Atrial Fibrillation James E. Tisdale, Matthew R. Allen, Brian R. Overholser, Heather A. Jaynes, Richard J. Kovacs, Purdue University, Indianapolis, IN, USA, Indiana University, Indianapolis, IN, USA 47 ‐ Absence Of QTc Prolongation With Betrixaban: A Randomized, Double‐blind, Placebo‐ And Positive‐controlled Thorough ECG Study Uma Sinha, Joel Morganroth, Daniel D. Gretler, Stanley J. Hollenbach, Joseph L. Lambing, Portola Pharmaceuticals Inc, South San Francisco, CA, USA Arrhythmias‐PosterContributionsSession#1107Arrhythmias:AF/SVTIISaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75



48 ‐ Left Atrial Appendage Morphologic Pattern Determined by Computed Tomography Is a Novel Predictor of High Risk Patient for Embolism with Atrial Fibrillation Nobuhiko Makino, Masami Nishino, Ayano Ishiyama, Akihiro Tanaka, Naotaka Okamoto, Naoki Mori, Yasuharu Lee, Takahiro Yoshimura, Daisuke Nakamura, Masayuki Taniike, Hiroyasu Kato, Yasuyuki Egami, Ryu Shutta, Hisaki Morita, Jun Tanouchi, Yoshio Yamada, Division of Cardiology, Osaka Rosai Hospital, Sakai, Japan 49 ‐ Post‐Procedural Dabigatran versus Standard Anticoagulation in Ablation for Atrial Fibrillation Jeffrey Lin, Bradley Knight, Prashant Bhave, Martha Bohn, Alexandru Chicos, Evaldas Giedrimas, Jeffrey Goldberger, Leonard Ilkhanoff, Susan Kim, Albert Lin, Taral Patel, Sharon Shen, Rod Passman, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA 50 ‐ Incidence, Characteristic and Risk Factors of Cerebral Thromboembolic Complications following High‐Frequency Catheter Ablation of Atrial Fibrillation: Experience of 3,360 Procedures Andreas Bollmann, Jedrzej Kosiuk, Jelena Kornej, Krzysztof Myrda, Arash Arya, Thomas Gaspar, Christopher Piorkowski, Philipp Sommer, Gerhard Hindricks, Gregory Lip, Heart Center, Leipzig, Leipzig, Germany 51 ‐ Catheter Ablation for Atrial Arrhythmias Rapidly Improves Thrombotic Profile over and above Therapeutic Anticoagulation Maria Niespialowska‐Steuden, Vias Markides, David Jones, Peter Collins, Wajid Hussain, Tom Wong, Diana Gorog, Imperial College, London, United Kingdom, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom 52 ‐ Comparison of Atrial Fibrillation Ablation Bleeding and Thrombotic Complications with Dabigatran, Rivaroxaban and Warfarin Michael Bernard, William Brabham, Peter Netzler, Christopher Rowley, Michael Gold, Robert Leman, John Sturdivant, J. Marcus Wharton, Frank Cuoco, Medical University of South Carolina, Charleston, SC, USA 53 ‐ Large Orifice and Decreased Flow Velocity of Left Atrial Appendage Are Strong Predictors of Stroke in Non‐Valvular Atrial Fibrillation Jung Myung Lee, Jaemin Shim, Jae‐Sun Uhm, Hui‐Nam Pak, Moon‐Hyoung Lee, Boyoung Joung, Yonsei University Health System, Seoul, South Korea 54 ‐ Association between Obesity and Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery: A Systematic Review and Meta‐Analysis Adrian V. Hernandez, Roop Kaw, Vinay Pasupuleti, Pouya Bina, John P.A. Ioannidis, Hector Bueno, Eric Boersma, Cleveland Clinic, Cleveland, OH, USA, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru 55 ‐ Left Atrial Appendage Volume as a Predictor of Embolic Stroke in Atrial Fibrillation Brian K. Whisenant, Lance D. Burrell, Benjamin Horne, J. Muhlestein, Jeffrey Anderson, Intermountain Medical Center, Salt Lake City, UT, USA 56 ‐ Atrial Natriuretic Peptide as a Predictor of Atrial Fibrillation in a Male Population Study: The Study of Men Born in 1913 Zacharias Mandalenakis, Henry Eriksson, Mikael Dellborg, Kenneth Caidahl, Lennart Welin, Kurt Svärdsudd, Saga Johansson, Georgios Lappas, Annika Rosengren, Per‐Olof Hansson, Institute of Medicine, Dept. of Molecular and Clinical Medicine/Cardiology, Sahlgrenska Academy, Gothenburg, Sweden 57 ‐ Impact of Non‐steroidal Anti‐inflammatory Drugs on Risk of Serious Bleeding and Thromboembolism in Atrial Fibrillation ‐ A Nationwide Cohort Study Morten Lamberts, Gregory Lip, Morten Lock Hansen, Jesper Lindhardsen, Jonas Bjerring Olesen, Jakob Raunsø, Anne_Marie Schjerning Olsen, Emil L Fosbøl, Christian Torp‐Pedersen, Gunnar Gislason, Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark

58 ‐ Characteristics and Outcomes of Patients with Atrial Fibrillation and Significant Valvular Lesions: Experience from the ROCKET AF Trial Guenter Breithardt, Helmut Baumgartner, Scott Berkowitz, Anne Hellkamp, Jonathan Piccini, Susanna Stevens, Yuliya Lokhnygina, Manesh Patel, Jonathan Halperin, Daniel Singer, Graeme Hankey, Werner Hacke, Richard Becker, Christopher Nessel, Kenneth Mahaffey, Keith Fox, Robert Califf, ROCKET AF Steering Committee & Investigators, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA, Department of Cardiovascular Medicine, University Hospital Muenster, Muenster, Germany ChronicCAD/StableIschemicHeartDisease‐PosterContributionsSession#1108MentalStressontheHeartSaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 59 ‐ Does Age Change the Effect of Depressive Symptoms on Mortality in Patients with Coronary Heart Disease? Pamela S. Miller, Lynn V. Doering, Sharon McKinley, Debra Moser, Barbara Riegel, Kathleen Dracup, University of California, San Francisco, San Francisco, CA, USA 60 ‐ Mental Stress Is Associated with Endothelial Dysfunction and Arterial Stiffness in Patients with Stable Coronary Artery Disease Ronnie Ramadan, Shabnam Seydafkan, Ibhar Al Mheid, Fabio Esteves, David Sheps, J. Douglas Bremner, Viola Vaccarino, Arshed Quyyumi, Emory University School of Medicine, Atlanta, GA, USA 61 ‐ Association between Platelet Aggregation and Mental Stress Induced Myocardial Ischemia: Results from the REMIT Trial Robert W. Harrison, Richard Becker, Thomas Ortel, Maggie Kuchibhatla, Stephen Boyle, Zainab Samad, Eric Velazquez, Jennifer Wilson, Cynthia Kuhn, Redford Williams, Christopher O'Connor, Wei Jiang, Duke University Medical Center, Durham, NC, USA 62 ‐ Relationship between Circulating Progenitor Cells and Myocardial Ischemia during Mental Stress Ronnie Ramadan, David Sheps, Ibhar Al Mheid, Malik Obideen, Fabio Esteves, J. Douglas Bremner, Viola Vaccarino, Arshed Quyyumi, Emory University School of Medicine, Atlanta, GA, USA 63 ‐ A Novel Approach for Detection of Coronary Artery Disease: Combination of Isometric Exercise and Emotional Stress Echocardiography Vadim A. Kuznetsov, Dmitriy Krinochkin, Elena Yaroslavskaya, Arkadiy Plusnin, Georgy Pushkarev, Tyumen Cardiology Center, Tyumen, Russian Federation ChronicCAD/StableIschemicHeartDisease‐PosterContributionsSession#1109ChronicCAD:MechanismsofRepairSaturday,March9,2013,9:30a.m.‐12:30p.m.PosterSessions,ExpoNorthCMEHours:0.75/CNEHours:0.75 64 ‐ Enhanced Circulating Soluble LR11 after Coronary Stenting, a Novel Marker of Smooth Muscle Cell Migration in Response to Vascular Injury Manabu Ogita, Katsumi Miyauchi, Meizi Jiang, Shuta Tsuboi, Ryo Naito, Hirokazu Konishi, Tomotaka Dohi, Takatoshi Kasai, Hideaki Bujo, Hiroyuki Daida, Juntendo University Graduate School of Medicine, Tokyo, Japan, Chiba University Graduate School of Medicine, Chiba, Japan 65 ‐ Endothelial Progenitor Cells Mobilization and Recruitment Correlate with Coronary Artery Disease Severity Niccolò Mancini, Chrysanthos Grigoratos, Maria Elena Lucia Picoi, Federica Massaro, Tatiana Santoni, Ottavia Balbi, Angela Pucci, Mariachiara Barsotti, Claudia Mattioli, Paola Collecchi, Uberto Bortolotti, Generoso Bevilacqua, Rossella Di Stefano, Alberto Balbarini, Cardiac, Thoracic and Vascular



Department, University of Pisa, Pisa, Italy, Division of Surgical, Molecular, and Ultrastructural Pathology, University of Pisa, Pisa, Italy 66 ‐ Novel Angiogeni

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