PHARMACEUTICO-ANALYTICAL STUDY OF TALESHWARA...

AAMJ / Vol. 4 / Issue 4 / July – Aug 2018

A A M J Anveshana Ayurveda Medical Journal

www.aamj.in ISSN: 2395-4159

Research Article

PHARMACEUTICO-ANALYTICAL STUDY OF TALESHWARA RASA

Lavanya S. A*

A b s t r a c t

Taleshwara Rasa is an eccentric formulation which is favourable in the management of 18

types of Kushta. Regardless of its betterment in the management of Kushta no research work

has been carried out till date. The main aim of this study was preparation of Taleshwara Rasa

as disclosed in the classics & Physico-chemical analysis of Taleshwara Rasa. Taleshwara

Rasa was processed using Kajjali, Haratala Bhasma, Shuddha Tankana, Shuddha

Vatsanabha , Shuddha Dhattura beeja, Jaatiphala, Bakuchi Beeja Churna, Nimba beeja

majja churna, Shunti Churna, Maricha churna, Pippali churna. The above ingredients were

mixed to get a homogenous mixture of Taleshwara Rasa which was given 7 Bhavana with

Guduchi patra swarasa followed by 7 bhavana of Dhattura patra swarasa. After bhavana a

bolus was prepared out of the mixture and Dhattura patra veshtana was done followed by

gomaya lepa and subjected to Kukkuta puta. The Physico chemical analysis of Taleshawara

Rasa before (TR-BB) and after bhavana (TR-AB) and after puta (TR-AP) was done.

Key words – Taleshwara Rasa, XRD, FTIR, SEM-EDAX.

*PG Scholar, Dept of Rasashastra and Bhaishajya Kalpana, Taranath Govt. Ayurvedic Medical College,

Bellary, Karnataka, India.

CORRESPONDING AUTHOR

Dr. Lavanya S. A. Dept of Rasashastra and Bhaishajya Kalpana,

Taranath Govt. Ayurvedic Medical College,

Bellary, Karnataka, India.

Email: [email protected]

http://aamj.in/wp-content/uploads/Volume4/Issue4/AAMJ_1798_1807.pdf

Lavanya S. A: Pharmaceutico-Analytical Study Of Taleshwara Rasa

AAMJ / Vol. 4 / Issue 4 / July – Aug 2018 1799

INTRODUCTION

asashastra is a branch of Ayurveda which deals

with metallo-mineral preparations aimed at

achieving Lohavada & Dehavada. These

preparations became acceptable due to its assimilatory

property in the minute doses. There are mainly 4 Rasa

Kalpas namely Khalviya, Parpati, Pottali & Kupipakwa

Rasayana. Taleshwara Rasa1(TR) is one such Khalviya

rasayana mentioned in the classics which have a distinct

method of preparation than any other formulation that is

beneficial in the management of Ashtadasha Kushta2. There

are numerous formulation in the name of Taleshwara Rasa

with different suffix and prefix. In the present study the

formulation is taken from the text Rasa Manjari.

The analytical study reveals the chemical composition of the

formulations as well as their concentration. By this it helps

to ensure safety limits and accuracy of the drug. Physico-

chemical analysis of the drugs is carried out by using current

analytical methodologies for understanding and

interpretation of physico-chemical changes occurring during

and after pharmaceutical processing. The Physico chemical

analysis of Taleshawara Rasa before bhavana (TR-BB) and

after bhavana (TR-AB) and after puta (TR-AP) was done.

MATERIALS AND METHODS

Pharmaceutical stride involved in preparation of

Taleshwara Rasa:

1. Preparation of homogenous mixture of Taleshwara

Rasa ingredients.

2. 7 Bhavana was given with Guduchi patra swarasa

followed by 7 bhavana of Dhattura patra swarasa

3. Preparation of bolus out of bhavita mixture of

Taleshwara Rasa.

4. Dhattura patra veshtana to the bolus followed by

Gomaya lepana.

5. Subjecting the Gomaya Lepita bolus to Kukkuta

puta.

Table 1: Showing the ingredients and their Quantity of

Taleshwara Rasa

Ingredients Quantity (g)

Shuddha Parada 14

Shuddha Gandhaka 21

Haratala Bhasma 70

Shuddha Tankana 70

Shuddha Vatsanabha 10.5

Shuddha Dhattura Beeja Churna 7

Nimba Beeja majja 7

Bakuchi beeja 21

Shunti 21

Maricha 28

Pippali 21

Jaatiphala 70

Procedure:

Kajjali and Haratala bhasma was taken in a clean khalwa

yantra and triturated for 2 hours to prepare a homogenous

mixture. To that Shuddha Tankana was added and mardana

was done for 2 hours. To this mixture the churna of

Jaatiphala followed by the churna of vatsanabha, dhattura

beeja, nimba beeja majja, bakuchi beeja, shunti, maricha

and pippali were added and triturated well to form a

homogenous mixture.

Bhavana of TR mixture with Guduchi patra swarasa:

Extraction of Guduchi patra swarasa:

Fresh and matured leaves of guduchi were collected and

washed to remove the impurities. Later the leaves were

taken in a mixer jar and grinded well into a paste. Then the

paste was placed on a two-folded Cora cloth and squeezed

to obtain fresh swarasa.

Procedure:

To the mixture of TR required quantity of guduchi patra

swarasa was added such that the mixture is completely

immersed in the liquid and mardana was carried out for 6

hours. Same procedure was repeated for 6 more times.

Bhavana of TR mixture with Dhattura patra swarasa:

Extraction of Dhattura patra swarasa:

Fresh and matured leaves of dhattura were

collected and washed to remove the impurities. Later the

leaves were taken in a mixer jar and grinded well into a

paste. Then the paste was placed on a two-folded Cora cloth

and squeezed to obtain fresh swarasa.

Procedure:

To the mixture of TR required quantity of dhattura patra

swarasa was added such that the mixture is completely

immersed in the liquid and mardana was carried out for 6

hours. Same procedure was repeated for 6 more times.

Observations:

The colour of the mixture which was dark blackish grey

colour after adding haratala bhasma to kajjali turned to

light grey colour after adding Shuddha Tankana.

After adding the churna of Kashtoushadhis the colour

was Light grey.

Characteristic odour of Jaatiphala was felt during the

mardana of TR mixture

During the extraction of Guduchi swarasa, sliminess

was felt and the swarasa was green in colour with

watery consistency.

During the extraction of Dhattura patra swarasa

characteristic odour of dhattura was felt and the colour

of swarasa was dark green in colour. Consistency was

thicker when compared to the guduchi patra swarasa.

Total duration taken for the completion of homogenous

mixture of TR was 4 hours.

R



In total 14 bhavana was given to the TR mixture. Each

Bhavana was carried out for 6 hours.

The amount of Swarasa used was reduced day by day.

Total quantity of Guduchi patra swarasa used was

2.410 ltrs and dhattura patra swarasa used was 2.485

ltrs.

The trituration strokes were 30-strokes/minute in initial

stage of Bhavana and it reduced to 20 strokes / minute

when the fluid portion decreased.

Precautions

Khalva Yantra should be clean and dry before the

process starts.

Daily fresh swarasa was used.

The pestle should be rotated entire length of Khalva

Yantra in both clock and Anti clock- wise directions.

Table 2: Showing the consumption of swarasa for 14 bhavana

Amount of Guduchi patra Swarasa used (in ml) for 7

bhavana

Amount of Dhattura patra Swarasa used (in ml) ) for 7

bhavana

400 ml 410 ml

375 ml 390 ml

360 ml 375 ml

345 ml 360 ml

330 ml 345 ml

310 ml 315 ml

290 ml 290 ml

Putana Karma for TR Mixture:

1. Preparation of Bolus of TR Mixture:

After giving Bhavana when the mass attained semisolid

consistency it was taken out from the khalwa yantra and

made into a bolus and kept for drying. After 3 hours of

drying small cracks started appearing on the surface of the

bolus. Then the bolus was subjected for further steps.

2. Dhattura Patra Veshtana for the Bolus:

Fresh and matured leaves of Dhattura was collected and

washed with water. It was then kept for drying. Later 5

leaves were selected and placed in a circular manner on the

stainless steel plate and bolus was placed over the leaves.

Then the bolus was covered with the leaves and secured

using a Cotton thread.

3. Gomaya Lepana for Bolus:

Freshly collected gomaya was placed on a plate and a base

of 2.5cm thickness was created. Above this the dhattura

patra veshtita TR was placed and the lepana of gomaya was

done with a thickness of 2.5 -3 cm. It was placed

undisturbed for drying. The surface of the Gomaya lepita TR

was changed every now and then in order to provide

complete drying of the lepana. It took 5 days for complete

drying of gomaya lepa.

4. Kukkuta Puta:

a) Size and Shape :Kukkuta Puta was

given by using the pit of following dimensions.

Size Of Pit : 31 cm Height , 31cm depth and

31cm width

b) Fuel : 30 cow dung cakes,

totally dried, each cowdung with Following dimension

Diameter : 13cm (on average)

Thickness : Centrally 4cm, periphery 2cm

Weight : 100grams (approx)

Total Weight : 3 kg

18 cow dung cakes were placed below the bolus and 12

were placed above to ensure uniform degree of heat.

c) Mode of Heating

Fire was ignited by keeping four small camphor balls

on all four sides.

Thermocouple tip was placed on the side of the Bolus

(upper 1/3rd of Puta).

Temperature obtained during Puta was recorded with

the help of Pyrometer.

After Swanga sheeta, the bolus was taken out of pit and

layers of gomaya and dhattura patra were scraped

carefully with knife.

The putita TR was collected, weighed, powdered and

stored in an airtight container.



Graph No 1: Showing Time Vs Temperature during Kukkuta puta of TR

Table 3:- Showing in process testing of Putita TR.

Sl.No. Name of Test Result

1 Colour Black

2 Taste Tasteless

3 Touch Mrudu

4 Appearance Fine powder

5 Odour Burnt Smell

Observations:

Slight cracks started appearing on the

surface of the bolus after 3 hours of

drying.

Colour of the bolus was Greenish Dark

Grey.

It was difficult to do lepana of gomaya

over the dhattura patra veshtana as the

gomaya was freshly collected.

It took 5 days for the complete drying of

gomaya lepa.

Kukkuta Puta:

The rise in temperature was up to 458o C for 25-30

minutes.

After Puta the bolus was in same form with

change in Colour.

Time taken for complete burning was 5-6 hours.

The bolus was completely burnt and the outer layer

of gomaya and dhattura patra was brittle in nature.

The inner bolus of TR which was soft and in

semisolid consistency had become brittle and the

colour was changed to black.

When the bolus was broken into two halves the

inner surface was shiny and brittle.

Table 4: Showing Pharmaceutical Results of TR

Analytical Study of Taleshwara Rasa:

Table 5: Showing Organoleptic & Physico-chemical analysis of TR

24

395458

386320

235142

65 28

0100200300400500

10:00 11:00 11:30 12:00 01:00 02:00 03:00 04:00 05:00Tem

pe

ratu

re in

0c

Time

Time and Temperature during kukkuta Puta of

TR

Result In Grams

Initial weight of TR mixture 360.5

Weight of TR mixture after Bhavana 410

Total Gain after bhavana 49.5

Weight after Puta 343.5

Loss of drug after puta 66.5

Parameters TR-BB TR-AB TR-AP

Colour Ash coloured Greenish Brown Brown

Touch Fine powder,

Amorphous

Fine powder,

Amorphous

Fine powder,

Amorphous

Odour Characteristic Characteristic Characteristic

Taste Pungent Pungent Tasteless

Total Ash w/w 43.50% 35.70% 48.50%

Acid Insoluble Ash w/w 41.25% 5.47% 6.85%

Water soluble Ash w/w 18.50% 29.50% 27.50%



XRD3 Results of TR-BB, TR-AB & TR-AP:

XRD peaks of TR-BB, TR-AB & TR-AP samples which were compared with standard D-space JCPDF values confirmed

the presence of Metacinnabar (HgS) in Cubic, Sulfur (S) in Trigonal, Mercury Oxide (HgO) in Hexagonal, Arsenic

Sulfide (As2S3) in Unknown, Calcite (CaCO3) in Trigonal, Calcium Arsenate ( Ca2(AsO4)2) in monoclinic and

Tincalconite (Na2B4O710H2O) in Trigonal crystal system.

Graph No 2: Peaks of TR-BB XRD Graph No 3: Peaks of TR-AB XRD

Graph No 4: Peaks of TR-AP XRD

Table 6: Showing Comparative SEM-EDX4 results of TR-BB, TR-AB & TR-AP

TR-BB TR-AB TR-AP

Element Mass% At % Mass% At % Mass% At %

Hg 0.66 0.05 2.65 0.19 3.86 0.40

S 0.82 0.42 1.74 0.80 3.87 2.48

Collected Data-3

0

500

1000

1500

2000

20 40 60 80

Theta/2-Theta[deg]

Inte

nsity

[cps]

Collected Data-2

0

500

1000

1500

2000

20 40 60 80

Theta/2-Theta[deg]

Inte

nsity

[cps]

Collected Data-1

0

500

1000

1500

2000

20 40 60 80

Theta/2-Theta[deg]

Inte

nsity

[cps]

Loss on Drying at 1050c 1.26% 3.55% 0.90%

pH 9.64 9.14 9.19

Alcohol Soluble extractive 21.38% 16.56% 8.95%

Water Soluble Extractive 26.54% 34.54% 32.75%

Mercury 3.50% 2.95% 6.10%

Free Mercury Nil Nil Nil

Mercurous Mercury 00.25% 00.38% 00.19%

Mercuric Mercury 3.25% 2.57% 5.91%

Sulphur 8.58% 6.41% 6.95%

Free Sulphur 00 00 00

Sulphide 8.51% 6.10% 6.50%

Sulphate 0.07% 0.31% 0.45%

Boron 2.67% 2.02% 2.91%

Arsenic 16.55% 14.75% 18.90%

Arsenite 14.65% 12.60% 14.45%

Arsenate 18.90% 14.45% 4.45%

Sodium 3.10% 3.16% 3.50%

Calcium 0.90% 1.43% 1.50%



B 26.58 40.06 22.64 30.95 13.70 26.04

As 20.31 4.42 11.15 2.20 26.92 7.38

Na 3.58 2.54 2.04 1.31 0.40 0.36

Ca 4.30 1.75 3.90 1.44 15.11 7.75

C 21.01 28.50 40.89 50.32 28.66 49.02

O 21.45 21.85 13.20 12.20 3.87 2.48

Fe 0.17 0.05 0.18 0.05 0.29 0.11

Zn 0.26 0.06 0.25 0.06 0.61 0.19

K 0.49 0.20 1.09 0.41 2.17 1.14

Cu 0.38 0.10 0.28 0.06 0.54 0.17

Graph No 5: Depicting EDAX of TR-BB Graph No 6: Depicting EDAX of TR-AB

Graph No 7: Depicting EDAX of TR-AP

FTIR5:

FTIR analysis of TR-BB & TR-AP shows it contains organic functional group like Alcohol, Amine, Amide, Acid, Alkene,

Alkane, Aromatic, Acid, Carbonyl, Nitro, Alkyl Halide, Aromatic, Ester and Ether.

FTIR analysis of TR-AB shows it contains organic functional group like Alcohol, Amine, Amide, Acid, Alkene, Alkane,

Aromatic, Acid, Carbonyl, Nitro, Alkyl Halide, Aromatic, Alkyne, Thiocyanate, Ester and Ether.

Graph No 8: TR-BB Graph No 9: TR-AB

5007501000125015001750200025003000350040001/cm

30

40

50

60

70

80

90

100

%T

3350.3

5

3016.6

72922.1

62852.7

2

2625.1

2

2509.3

9

2345.4

4

1735.9

3

1656.8

51637.5

6

1421.5

41371.3

91344.3

8

1130.2

91103.2

81080.1

41004.9

1945.1

2

873.7

5831.3

2771.5

3

713.6

6 464.8

4

TR-BB

5007501000125015001750200025003000350040001/cm

30

40

50

60

70

80

90

100

%T

3550.9

53471.8

7

3300.2

0

2920.2

32852.7

2

2522.8

9 2281.7

9

2164.1

3

1734.0

11668.4

31639.4

9

1537.2

7

1444.6

81413.8

2

1340.5

3

1109.0

7

1035.7

7

871.8

2839.0

3

717.5

2

TR-AB



Graph No 10: TR-AP

Particle Size Results6:

Table 7: Showing Particle Size Results of TR-BB, TR-AB, TR-AP

Effective Diameter(nm)

Sample Mean diameter(nm) Standard error Effective diameter(nm)

TR-BB 839.6 42.6 821.8

TR-AB 1055.7 97.2 1183.0

TR-AP 757.1 19.4 764.8

HPTLC7 results

Table 8:- Showing Rf values of TR-BB, TR-AB, TR-AP at 254nm & 366nm

At 254 nm At 366 nm

TR-BB TR-AB TR-AP TR-BB TR-AB TR-AP

0.18(D. green) 0.18(D. green) 0.18(L. green) 0.04 (F. blue) 0.04 (F. blue) 0.04 (F. blue)



0.53 (L. green) 0.53(L. green) 0.53(L. green) 0.27 (F. blue) 0.27 (F. blue) 0.27 (F. blue)

0.60 (L. green) 0.60(L. green) 0.60(L. green) 0.37 (F. blue) 0.37 (F. blue) 0.37 (F. blue)


0.78 (Green) 0.78 - 0.55 (F. blue) 0.55 (F. blue) 0.55 (F. blue)

0.86 (L. green) 0.86 - 0.61 (F. blue) 0.61 (F. blue) 0.61 (F. blue)

Table 9:- Showing Rf values of TR-BB, TR-AB, TR-AP after post derivatisation

TR-BB TR-AB TR-AP

0.10 (Purple) 0.10 (Purple) 0.10 (Purple)









0.80 (Purple) 0.80 (Purple) -

0.89 (Purple) 0.89 (Purple) -

5007501000125015001750200025003000350040001/cm

30

40

50

60

70

80

90

100

%T

3332.9

9

2922.1

62854.6

5

2524.8

2

1861.3

1

1653.0

0

1436.9

7

1105.2

1

873.7

5837.1

1

711.7

3

626.8

7

TR-AP



Graph No 11: 3D Chromatogram at 254nm Graph No 12: 3D Chromatogram at 366 nm

Graph No 13: 3D Chromatogram at 620nm

DISCUSSION

Pharmaceutical study: Preparation of TR mixture:

TR was prepared step by step. Kajjali and Haratala

bhasma was taken in a clean khalwa yantra and triturated for

2 hours to prepare a homogenous mixture. To that of

Shuddha Tankana was added and mardana was done for 2

hours. To this mixture the churna of Jaatiphala followed by

the churna of Vatsanabha, dhattura beeja, nimba beeja

majja, bakuchi beeja, shunti, maricha and pippali were

added and triturated well to form a homogenous mixture.

Bhavana of TR mixture with Dhattura Patra & Guduchi

Patra swarasa

To the mixture of TR required quantity of dhattura

patra swarasa was added such that the mixture is

completely immersed in the liquid and mardana was carried

out for 6 hours. Same procedure was repeated for 6 more

times. It is then followed by 7 bhavana of Guduchi patra

swarasa.

In a study it has been explained that a total of 12

elements have been reported quantitatively that includes

Cu, Co, Ni, Mn, Zn, Fe, Na, K, Ca, Mg, P & Al7.

Dhattura leaves are mineral rich than their seeds and

flower counterparts. This is suggestive that dhattura

patra swarasa not only helps in relieving the disease

condition but also imbibe few of these trace elements

required to the body into the formulation.

Phytochemical screening of leaf of guduchi indicates

the presence of alkaloids, glycosides, carbohydrates,

saponins, phenols, phytosterols, tannins and amino-

acids and suggested that it is an important source of

bioactive compounds that may supply novel medicine.

It is also richer in anti-oxidants which are helpful in

counteracting the free radicals of the disease.

Both Dhattura and Guduchi have Tikta rasa, Laghu,

ruksha guna, Ushna veerya which helps in removal of

kapha dosha and does kledaharana that are considered

as the root cause of the disease Kushta.

Putana karma of TR:

A bolus of bhavita TR was prepared and dhattura

patra veshtana was done followed by gomaya lepa and

allowed for drying. Then it was subjected for kukkuta puta

once.

The layer of Dhattura patra and gomaya act as

protective covering in order to avoid the direct contact

of heat with the drug mixture. If direct heat is given

then the formulation might get carbonised as it contains

major amount of organic compounds as ingredients.

Gomaya has Kashaya rasa and ushna veerya which

helps in kleda shoshana of the body. As it is subjected

to puta there is a chance of chemical reaction occurring

between the Dhattura patra, gomaya and drug mixture

due to which the medicinal properties of dhattura and

gomaya might be induced into the drug.

After 14 bhavana due to the usage of organic media for

levigation the particle size of the drug might increase which

in turn decrease the absorption in the body. In putana karma

organic compounds undergo carbonisation and the particle

size gets reduced which helps in easy absorption and

assimilation of the drug. Hence puta is given after the

completion of Bhavana.

Analytical Study:

Total ash value helps to know about inorganic material

in the test drug. Total ash value of TR-BB, TR-AB &

TR-AP is found to be 43.50%, 35.70% & 48.50%. This

indicates less amount of inorganic material in the

sample, and 56.5%, 64.3% & 51.5% is organic that is

bio-human available products. The ash value after

Bhavana is decreased to 35.70% which indicates that



the amount of organic material has become more after

Bhavana which is suggestive of the presence of organic

compound of the Bhavana drugs also.The ash value

after putana karma has been increased to 48.50% which

indicates that the organic matter present has been

carbonised due to the heat supplied during putana

karma.

Acid insoluble ash of TR-BB, TR-AB, TR-AP are 41.25%,

5.47% and 6.85% respectively indicating that 93.15% of

the drug is easily soluble in the gastric environment.

It indicates selective media of drug administration. Water

soluble ash value of TR-BB, TR-AB, TR-AP is 18.50%,

29.50% & 27.50% respectively indicating less solubility

of the drug in water media. TR is a herbo-mineral

formulation; the presence of inorganic substance in the

formulation might make this drug less soluble in the

water media.

The least loss on drying at 1050C, the better will be the

drug. In the present study TR-BB, TR-AB, TR-AP

possesses 1.26%, 3.55% and 0.90% respectively. Hence

it can be stated that all have very less amount of moisture

content and very rare chance of bacterial and fungal

growth. The drug is having least hydroscopic activity

with less chance of contamination of drug. Concurrently

it can be stated that the shelf life of the drug in the

present study is more.

Water soluble and Alcohol Soluble extractives indicates

the mode of administration of the drug. Alcohol soluble

extractives of TR-BB, TR-AB & TR-AP are 21.38%,

16.56% & 8.95% whereas water soluble extractives are

26.54%, 34.54% & 32.75%. This indicates that water is

not suitable media for the TR administration and

extraction.

The percentage variation of arsenic compound may be

due to formation of various compounds with oxygen and

sulphur.

The percentage of carbon has been increased in TR-AB

compared to TR-BB; it may be due to the addition of

organic material. The percentage of carbon decreased in

TR-AP compared to TR-AB, it may be due to the

carbonization of organic substances during putana

karma.

The reduction in oxygen percentage gradually in TR-BB,

TR-AB, and TR-AP may be due to the oxidation process.

The elements like Boron, Sodium are detected due to

Tankana which is one of the major ingredients of TR.

The increase in the percentage of sulphur and calcium

may be due to conversion of elemental calcium and

sulphur into compound form.

The other minor elements like K, Fe, Zn, Cu may be due

to the 7 Bhavana of TR with Dhattura patra swarasa as

mentioned earlier dhattura leaf are mineral rich

containing 12 elements.

The increase in particle size after Bhavana may be due to

the Bhavana of the drug with the swarasa of organic

material as the particles of organic material will not

reduce to nanometre scale. The reduction in particle size

of TR-BB compared to TR-AP may be due to putana

karma.

In present study HPTLC of the drug mixture is compared

with the final product. The final product shows the

presence of various herbal ingredients present in the

formulation and hence show that the preparation is not

adulterated.

CONCLUSION

Taleshwara Rasa is one of the Khalviya rasayana. There are

many references with different prefix available with

variation in the ingredients method of preparation and

dosage. Among them, Rasa Manjari reference was selected

for the preparation. In total there was 18.44% loss in the

weight during the pharmaceutical preparation of the drug.

Chemically Taleshwara Rasa is considered as a compound

of Metacinnabar, Sulfur, Mercury Oxide, Arsenic sulphide,

Calcite, Calcium Arsenate, Tincalconite with the organic

compounds with their functional groups like Alcohol,

Amine, Amide, Acid, Alkene, Alkane, Aromatic, Acid,

Carbonyl, Nitro, Alkyl Halide, Aromatic, Ester and Ether.

ΛΛΛΛ

REFERENCES

1. Acharya Shalinath. Rasa Manjari. Hindi commentary by Prof.

Siddhi Nandan Mishra, 2nd Edition. Varanasi: Published by

Chaukambha Orientalia; 2003. 6th Chapter, Verses 252 – 256,

113 pp.

2. Acharya Agnivesha. Charaka Samhita. Edited byVaidya

Yadavji Trikamji Acharya. Varanasi: Chaukambha Sanskrit

Samsthana; 2008. Chikitsasthana, 7th Chapter, Verse 13, 451

pp.

3. www.unm.edu/xrd/xrdbasics.pdf.

4. serc.carleton.edu.en.wikipedia.org/wiki/Energy-dispersive_X-

ray_spectroscopyCachedSimilar

5. www.wcaslab.com,mmrc. caltech. edu/FTIR/FTIRintro.pdf.

6. www.Zeta potential analysier.pdf.

7. Kasture A.V. Mehadik R. et.al. Pharmacopieal Analysis.

Pune: Nirali Prakashan; 2002.vol 5,13-18pp.

Source of Support: Nil.

Conflict of Interest: None declared

ΛΛΛΛ

How to cite this article: Lavanya S. A: Pharmaceutico-

Analytical Study Of Taleshwara Rasa. AAMJ 2018; 4:

1798 – 1807.



PHOTOS

Fig No:1 Fig No:2 Fig No:3

Parada & Gandhaka for Kajjali Kajjali Haratala Bhasma


Shuddha Tankana Shuddha Vatsanabha Shuddha Dhattura

Fig No: 7 Fig No:8 Fig No:9

Ingredients of TR Bhavana of TR Mixture Bolus prepared out of

TR Mixture


Dhattura patra veshtita Gomaya Lepita TR bolus Gomaya lepita TR bolus placed

TR Bolus in kukkuta puta pit

Fig No: 13 Fig No: 14 Fig No: 15

Gomaya Lepita TR Bolus TR bolus after puta Taleshwara Rasa

PHARMACEUTICO-ANALYTICAL STUDY OF TALESHWARA...

Documents

Transcript of PHARMACEUTICO-ANALYTICAL STUDY OF TALESHWARA...