Pathanatomy Lecture - 02 Cell Injury

41
&#&# &#&# %&# %&# !% !%  %$!#$%  %$!#$%  $!#$#%$'%$  $!#$#%$'%$

Transcript of Pathanatomy Lecture - 02 Cell Injury

Page 1: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 1/41

&#&#&#&#

%&#%&# !%!%

 %$!#$% %$!#$% $!#$#%$'%$ $!#$#%$'%$

Page 2: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 2/41

%#&%%#&%

$97:.9:70841;3889028,70349$97:.9:70841;3889028,70349.4389,39.4389,39

%0,70/0897:.9:70/,3/7089470/%0,70/0897:.9:70/,3/7089470/.4393:4:8.4393:4:8

;347,3828,-847-,3/ ;347,3828,-847-,3/097,.957490385/81,98097,.957490385/81,98

.,7-4/7,908,3/907.,7-4/7,908,3/907

.425430398,80,8,907438.425430398,80,8,907438

,3/520398,3/520398

Page 3: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 3/41

3974/:.9433974/:.943

;38890283.:/3.08,3/ ;38890283.:/3.08,3/

097,.0:,72,97,-847-1708097,.0:,72,97,-847-1708

8:-89,3.08,3/097,.9574/:.98418:-89,3.08,3/097,.9574/:.9841

907209,-4828907209,-4828

!45059/08543:.049/08,3/!45059/08543:.049/08,3/548,..,7/085,902489548,..,7/085,902489

831.,3974094209,-40831.,3974094209,-40

Page 4: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 4/41

3974/:.9433974/:.943

;0747,382-4/.43889841;0747,382-4/.4388984147,3847,38

;0747,3.43889841988:08;0747,3.43889841988:08

%88:0.43889841.08%88:0.43889841.08

0.43889841:97,897:.9:7080.43889841:97,897:.9:708

Page 5: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 5/41

3974/:.9433974/:.943

%070,70988:080590:2%070,70988:080590:2

/07;,9438174220803.2,988:0/07;,9438174220803.2,988:0

.4330.9;0988:01,99988:08-4308.4330.9;0988:01,99988:08-4308

.,79,082:8.08;08808.,79,082:8.08;08808

07;4:8988:0807;4:8988:08

4302,774988:084302,774988:08

25,9.988:0825,9.988:08

Page 6: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 6/41

3974/:.9433974/:.943

%0.,341.,308/0;0458%0.,341.,308/0;0458

:3/078:5073472,507:3/078:5073472,5073472,,3/5,944.,3472,,3/5,944.,

574.0880838/0.08,3/097,574.0880838/0.08,3/097,

.0:,72,97.0:,72,97

Page 7: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 7/41

&#&#&#&#

%%'#%%'#

#%##%#

&%&#$&%&#$

$$%$$%$$$$%$$%$$

 !%% !%%

#'#$$#'#$$

##'#$$,8##'#$$,8

#$$&#%#$$&#%

,:9488,3/0907488,:9488,3/0907488

Page 8: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 8/41

&#&#&#&#

 :9488890720/801/08943 :9488890720/801/08943

-848420803208-848420803208

0907488890720//089430907488890720//08943

-8484208414907.08-8484208414907.08

Page 9: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 9/41

&#&#&#&#

#0;078-0.,30847.0:,7#0;078-0.,30847.0:,7/00307,943475,703.2,/89745/00307,943475,703.2,/89745

..47/394 ..47/394209,-4./89:7-,3.0209,-4./89:7-,3.0

9070,705749031,99.,7-4/7,90,3/9070,705749031,99.,7-4/7,90,3/43/00307,943843/00307,9438

 ..47/3944.,,943 ..47/3944.,,943

9070,705,703.2,.0:,79070,705,703.2,.0:,720803.2,89742,20803.2,89742,;,8.:,7;,8.:,7

 3/20/70;078-0.,30847 3/20/70;078-0.,30847/00307,9438/00307,9438

Page 10: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 10/41

Page 11: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 11/41

&#&#&#&#

0.,38284170;078-03:70.,38284170;078-03:7

0.4254894341202-7,3080.4254894341202-7,308

5073197,943418:-89,3.085073197,943418:-89,3.08397,.0:,7,..:2:,943397,.0:,7,..:2:,943

&33,9:7,8390808&33,9:7,8390808

8-,,3.041.,.:2209,-4828-,,3.041.,.:2209,-482 %!/050943 %!/050943

7007,/.,7007,/.,3/:.0/3:73/:.0/3:7

Page 12: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 12/41

&#&#&#&#

0:,73:7/0503/843.00:,73:7/0503/843.0

95024.,7/,.08/083

95024.,7/,.08/083

23-:905/0728.08/08300823-:905/0728.08/083008

,1907.,:800944.,0398,.90/,1907.,:800944.,0398,.90/

0309.2,0:50309.2,0:5 ,/,59,-905,9..08,702470,/,59,-905,9..08,702470

,/,59;0.0890330:7438,/,59;0.0890330:7438

89,9:83472,475079745.89,9:83472,475079745.

Page 13: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 13/41

&#&#&#&#

0:,73:7/0503/8433:70:,73:7/0503/8433:7

9508.02,47310.9;0,0399508.02,47310.9;0,03998/:7,94398/:7,943

9880;0799880;079

Page 14: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 14/41

0:,73:70:,73:7

4.,7/,..0-0.42084.,7/,..0-0.420834.4397,.9034.4397,.90 339423:9089423:908 ,19078.02,89,90/,19078.02,89,90/

99 /083/083 23:90823:908 ,19078.02,,19078.02,

89,790/89,790/:9:9:97,897:.9:7,0;,:,943:97,897:.9:7,0;,:,943 41.,30841.,308

,550,783,550,7834:784:78 ,19078.02,89,790/,19078.02,89,790/

,3/,3/92.748.45.,0;,:,94392.748.45.,0;,:,943 -0.4208-0.4208

5488-05488-0 334:784:78 ,19078.02,,19078.02,

89,790/89,790/

Page 15: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 15/41

#'#$#'#$

0:,73:70:,73:7

%#&##$!$&$%#&##$!$&$

70,94341397,202-7,34:85,79.0870,94341397,202-7,34:85,79.08

3/45,82.709.::28033/45,82.709.::2803

8507843417-4842088507843417-484208

08030803

:253413:.0,7.742,93

:253413:.0,7.742,93

94.43/7,80394.43/7,803

$2,/03890893294.43/7$2,/03890893294.43/7

Page 16: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 16/41

8974547/00307,9438974547/00307,943

8905,944.574.0888905,944.574.088

.4330.90/9.4330.90/9/89:7-,3.0841988:0/89:7-,3.0841988:0

209,-4820,/394209,-4820,/394

897:.9:7,/847/078897:.9:7,/847/078

Page 17: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 17/41

,881.,9438,881.,9438

4170;078-03:74170;078-03:7 .,881.,943,..47/3944.,943.,881.,943,..47/3944.,943

!,703.2,.0:,7/00307,94347!,703.2,.0:,7/00307,94347

/89745/89745

$9742,;,8.:,7 $9742,;,8.:,7 

0/0/

Page 18: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 18/41

Page 19: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 19/41

&&%&&%

!%!%!%$#%!%$#%

%#&#&&%%#&#&&%

$%#'$&#$%#'$&#

 &&% &&%

Page 20: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 20/41

#'#$#'#$

0:,73:70:,73:7

397,.0:,7,..:2:,943397,.0:,7,..:2:,943

0:,780347/745.0:,780347/745./89745/89745

5/,..:2:,9435/,..:2:,943

.403,..:2:,943.403,..:2:,943

Page 21: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 21/41

#'#$#'#$

0:,73:70:,73:7

,881.,943,..47/394.0:,7,881.,943,..47/394.0:,7/8574903488/8574903488

0:,780347/745.;,.:400:,780347/745.;,.:40/8974547/00307,943/8974547/00307,943

,30/74509/8974547,30/74509/8974547

/00307,943/00307,94350707,93,94350707,93,943

Page 22: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 22/41

0:,7803470:,780347

/745./89745/745./89745

438/8-,,3.0-0900384/:2438/8-,,3.0-0900384/:2,3/549,88:29,907-:--0,3/549,88:29,907-:--0

1472,9431472,943

!749033197,94393.08!749033197,94393.08

0:,7202-7,308/0897:.9430:,7202-7,308/0897:.943

Page 23: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 23/41

0:,7803470:,780347

/745./89745/745./89745

80,80880,808

310.9;0/80,808310.9;0/80,808

05745,905745,9

743.4207:4305798743.4207:4305798

.44./80,80.44./80,80

0207/80,80 0207/80,80

Page 24: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 24/41

0:,7803470:,780347

/745./89745/745./89745

7,38,70,81447,38,70,8144

/30/30;07 ;07 

$305/0728$305/0728

7,330:74387,330:7438

Page 25: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 25/41

0:,7803470:,780347

/745./89745/745./89745%09:-:,7

;,.:4,943,3/

9:-:,7/,9430708,708:9419094.

0110.94109030

.4548433

%0/30

Page 26: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 26/41

,30/745098/89745,30/745098/89745

47/00307,94347/00307,943

070,70,47070,70,47

-4/089070/-4/089070/

4-:,72,907,4-:,72,907,.425480/41.425480/41

.948009,1,20398.948009,1,20398

3;07.083;07.08

.743.,/,2,0/.743.,/,2,0/1742,.44821742,.4482

Page 27: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 27/41

%#&#%#&#

&&%&&%

%%%% $%%$$   $%%$$  

!#!$$!#!$$

$#%##$#%##

 &&% &&% %##$%##$

%!#$%!#$

#$%'##$%'#%% #&#&

%$%$

Page 28: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 28/41

%%$%%$

%'#%'# %% $%$!#%$%$!#%

&%#%%$&%#%%$

%&$$%%&$$% !%$$!%$$$$

$%#'$%#'

&%$%#%&%$%#%!$!%%$!$!%%$

Page 29: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 29/41

!%$$!%$$

%%'#%%'# $$$#!%1,99,./8$$$#!%1,99,./8

,3/97.07/08,3/97.07/08

#0/:.0/&9,9434190243#0/:.0/&9,9434190243294.43/7294.43/7

0.70,803,54574903574/:.9430.70,803,54574903574/:.943

Page 30: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 30/41

%$%#!$%$%#!$

$$&%#$$&%# &#%$$&#%$$

'#'#

$$$#$$$#&$&$

%$%&$

%$%&$$%$%

$%#'%$%#'%

!$!$

Page 31: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 31/41

%$%#!$%$%#!$

$$&%#$$&%#

74888,250

.748,250

89,38$:/,3

Page 32: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 32/41

#$&%$#$&%$

#'#$%##'#$%#

$%#&%&#$%#&%&#

!%%$!%%$

##$$##$$

Page 33: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 33/41

397,.0:,7.,308,8397,.0:,7.,308,8!,703.2,/89745!,703.2,/89745

%%$%%$

%#%%#%

Page 34: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 34/41

%%$%%$

%#%%#% %%

!%%!%%

!%$$!%$$

41%/0.70,8341%/0.70,83

4/,9;0548547,9434/,9;0548547,943,3,074-..488,3,074-..488

/0.70,83%!839088/0.70,83%!839088

294.43/743/0897:.943294.43/743/0897:.943

3-943411,99,./4/,9433-943411,99,./4/,943

9438.,:8080;070/,2,041202-7,3089438.,:8080;070/,2,041202-7,308,3/0320889028,3/0320889028

Page 35: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 35/41

!74430/24/07,9054,708:983!74430/24/07,9054,708:983

14.,397,.0:,71,9/05489814.,397,.0:,71,9/054898

#$$#$$

 !!#%$

#&%#%%$####

&''#%%#%

% %##%

$0;0701,99.,308

574/:.0/-57414:3/

54,9/11:80/04

  .4470/2 4.,7/:2

Page 36: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 36/41

$2,/745098415/$2,/745098415/

,7014:3/93,7014:3/93

24.,7/,.0824.,7/,.08!74430/24/07,90!74430/24/07,90

54,708:9834.,54,708:9834.,

397,.0:,71,9/054898397,.0:,71,9/054898

,..47/394;034:8,..47/394;034:8-44/.40.943-44/.40.943 .748,250

89,38$:/,3

Page 37: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 37/41

%%$%%%$%

#%##%##%##%# 90748.0749.5,6:0.439,38 90748.0749.5,6:0.439,38

.4089074,3/9808907893.4089074,3/9808907893

2,.745,08,3/824492:8.0.082,.745,08,3/824492:8.0.0814,2.0814,2.08

 1907.0/0,9.4089074,3/98 1907.0/0,9.4089074,3/98

089078,7080034:941.08089078,7080034:941.08

Page 38: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 38/41

479,9,90748.0749.479,9,90748.0749.

5,6:085,6:08

$9,041,90748.07488$9,041,90748.07488

890720/5/488890720/5/488

4,2.08934,2.0893

,90748.0749.5,6:0,90748.0749.5,6:0

7488

2.74

Page 39: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 39/41

##%##%

#%#% ,7-4/7,90!,703.2,,-3472,9,7-4/7,90!,703.2,,-3472,9

8/;/0/394/847/07841.403,3/8/;/0/394/847/07841.403,3/

.457490/8.457490/8

80,808,7080,808,70/,-0908209:8/,-0908209:8 ,3/,3/

070/9,7070/9,7 .4038947,0/80,808.4038947,0/80,808

3,20/3,20/ .403480847.40348084790,:78248890,:782488

Page 40: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 40/41

,-0908209:8,-0908209:8

507.4802,0,/94507.4802,0,/94

.403,..:2:,943.403,..:2:,943

93703,9:-:,793703,9:-:,70590:20590:2

089889,30/-089889,30/-

,7230,7230

7284372843  .4470/.4470/7,3:087,3:08 41.40341.403

Page 41: Pathanatomy Lecture - 02 Cell Injury

8/14/2019 Pathanatomy Lecture - 02 Cell Injury

http://slidepdf.com/reader/full/pathanatomy-lecture-02-cell-injury 41/41

0:,73:70:,73:7

%003/%003/