Mcq in Pharma Cog Nosy A

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    Contents

    1. Simple choice ..............................................................................................................................22. Multiple choice..........................................................................................................................153. Grouping....................................................................................................................................30

    4. Relation analysis .......................................................................................................................435. Answer keys ..............................................................................................................................47

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    1. Simple choice

    Select the correct answer by marking the appropriate capital letter. There is only one correct

    answer.

    1. The volatile oils are the complex mixture of.

    A) mono- and sesquiterpenes as well as phenyl-propane derivatives.B) mono- and diterpene alcohols and ethers.C) sesquiterpenes and other aromatic compounds.D) monoterpene acids and lactones.E) monoterpene ethers and aldehydes.

    2. Sesquiterpenes are formed of............in the plants.

    A) farnezyl-pyrophosphateB) stress compoundsC) colouring materialD) degraded products of triterpenesE) pathological products

    3. What are known as balsams?

    A) resins dissolved in volatile oilB) a mixture of volatile oils with sesquiterpenesC) resins dissolved in waterD) polysaccharide mixed with volatile oilE) juice evaporated to dryness

    4. Saponin containing drugs are used as...........

    A) laxative.B) bitter tonic.C) expectorant.

    D) emetic.E) pain killer.

    5. Alkaloids are naturally occurring compounds which contain .............in their molecules.

    A) one or more N atom(s)B) two heterocyclic ringsC) one C15 side chain on the benzene ringD) one or more N atom(s) originated from amino acidsE) one or more O atoms besides the S atoms

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    6. How to extract the alkaloids in mineral salt form from plant?

    A) Heating with organic solvent.B) Boiling with ammonium-hydroxide and water.C) Shaking with water containing mineral acid.

    D) Boiling with water and lead acetate.E) Warming with mineral acid in organic solvent.

    7. The volatile oils consist of a mixture of.........

    A) oxygen free mono- and diterpenes.B) aliphatic and cyclic mono- and triterpenes.C) aliphatic and cyclic mono- and sesquiterpenes and phenyl-propane derivatives.D) highly oxygenated mono- and diterpenes.E) oxygen free di- and monoterpenes.

    8. The iridoids are:

    A) constituents of volatile oils.B) starting unit of the tannin biogenesis.C) precursor of biosynthesis of saponins.D) precursors of the biogenesis of certain alkaloids.E) constituents of fixed oils.

    9. What do you do for getting alkaloids in basis form from the plant material?

    A) Adding some ammonium-hydroxide and water to the pulverised drug.B) Making an extract by mineral acid and organic solvent.C) Making an extract with some basis and organic solvent.D) Adding to the powdered drug some mineral acid and water.E) Making an extract with organic solvent and warm it.

    10. Morphin is separable from its side alkaloids because:

    A) morphine has a piperidine ring.B) morphine has two methoxy groups.C) morphine has phenolic hydroxyl group while the side alkaloids have none.

    D) morphine has no phenolic hydroxyl group while the side alkaloid has it.E) morphine and its side alkaloids are inseparable.

    11. Which is the right reagent for the detection of rancidity?

    A) concentrated nitric acidB) phloroglucinol dissolved in diluted HClC) antimony-III-chlorideD) concentrated sulphuric acidE) phloroglucinol dissolved in ether and concentrated HCl

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    12. Choose the right skeleton for Cinchona alkaloids.

    A) cevanB) tropaneC) isoquinoline

    D) rubanolE) dammarane

    13. Choose the right reagent for alkaloids.

    A) 2,4-dinitrophenylhydrazineB) iron-III-chlorideC) antimony-III-chlorideD) potassium-tetraiodomercurateE) phloroglucinol in concentrated hydrochloric acid

    14. How could be prepared a mucilage extract starting from Linseed?

    A) After grinding some water is added to the seed and warm it.B) The seed is covered with water without grinding and warming.C) After grinding some alcohol is added to the seed.D) Without grinding some alcohol is added to the seed.E) After grinding it is covered with water without warming.

    15. Ergot is the......................of the fungus Claviceps purpurea.

    A) vegetative formB) dried sclerotiumC) ascosporeD) conidiosporeE) philamentous hyphae

    16. What is the difference between the chemical structure of cotton and starch?

    A) Cotton consists of lines -glucose molecules while the starch has branched-glucose residue.

    B) Cotton consists of unbranched -glucose molecules the starch has also unbranched

    - and -glucose molecules.C) Cotton is built up of glucose residues united by 1,4--D-glucose links, starch hasbranched and linear chains of 1,4--, and 1,6--D-glucose residue.

    D) Both consist of branched and linear 1,2--D-glucose residues.

    17. The haemolytic index shows:

    A) the di- and sesquiterpene content of the volatile oils..B) the saponin content of the drugs.C) the steroid content of the drugs.D) the aliphatic monoterpene content of the drugs.

    E) the tannin content of the drugs.

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    18. Which is the right structure for the flavonoids of Silybum marianum?

    A) dimer flavan-3,4-diolB) monomer flavon-3-olC) flavanolignan

    D) simple flavanonol-glycosideE) isoflavanon-diglycoside

    19. Cocaine is used as...................in the officinal medicine.

    A) narcoticB) emeticC) sedativeD) local anaestheticE) cough suppressant

    20. Choose the right test for identification of anthraquinones.

    A) Marquis testB) Froehde testC) Liebermann-Burchard testD) Borntreger testE) Murexid test

    21. How to detect the procyanidins?

    A) On heating with diluted NaOH procyanidines show green colour.B) Procyanidins give yellow colour on concentrated nitric acid.C) On heating with a mixture of cc. HCl and N BuOH procyanidines show red colour.D) On heating with resorcinol procyanidins give bluish violet colour.E) Procyanidins give orange precipitate on Kedde reagent.

    22. The anthraquinone content of the drugs tested by ............................

    A) warming with glacial acetic acid giving red precipitate.B) shaking the extract made by organic solvent with diluted ammonium-hydroxide the

    water phase gives red or orange colour.

    C) extracting with water and precipitate with lead acetate showing blue colour.D) making a water extract which shows green colour on sulphuric acid.E) making organic solvent extract which shows yellow precipitate on heating with

    dil. HCl and chlorine.

    23. What is the right method for making assay for volatile oil content of drugs?

    A) water-damp distillationB) extraction of light petrolC) distillation by Marcussons methodD) determination of loss on drying

    E) determination of alcohol extract

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    24. Which is the right test for the cardioactive glycosides of Foxglove leaf?

    A) MurexideB) Liebermann- BurchardC) EP

    D) 2,4-dinitro-phenylhydrazineE) Keller-Kiliani

    25. Which of the following compounds makes model for the synthesis of methyl-psoralens?

    A) chinineB) ephedrinC) tubocurarinD) xanthotoxinE) cocaine

    26. How to take a sample of plant drug material according to the prescription ofpharmacopoeia?

    A) 1000g of drug is taken off the upper part of the container.B) 100 or 200g drug has to be taken the side of the container.C) The number of sample depends on the number of container (N) or square root of N

    (at higher N). The samples has to be taken from different parts of container and theamount of the sample must be sufficient for the further analysis.

    D) Depends on the number of the container and volume of the sample.E) The amount and number of the sample are determined on the basis of the water

    content of the drug.

    27. Choose the right shape for the maize starch.

    A) ovalB) roundedC) pentagon with a V form fission in the middle of the grainD) triangularE) dumb-bell shaped

    28. Why cant use for medical purpose Rheum raponticum instead of Rheum palmatum?

    A) Because the emodin content of Rheum raponticum is too much.B) Because the rhein content of the Rheum raponticum is too low.C) Because the chrysophanol content of Rheum palmatum is higher than in case of

    Rheum raponticum.D) Because the Rheum raponticum contains a stilben derivative which has undesirable

    hormon activity.E) Because the R. raponticum has gallic acid and the amount of other tannins are too

    low.

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    29. Which of the following compounds transforms to chamazulen on Waterdampdistillation?

    A) lavandulolB) farnezol

    C) matricineD) gossypolE) parthenolid

    30. Which compound makes model for the synthesis of petidin?

    A) psoralenB) cocaineC) hyoscyamineD) morphinE) physostigmine

    31. Which of the following drug(s) contain(s) citric acid in a large amount?

    A) Bearberry leafB) Elder flowerC) Herniariae herbaD) Tamarindi fructusE) Violae odoratae radix

    32. How to get fixed oil for medical purpose?

    A) by extraction with a cold organic solventB) by warm expressionC) by extraction with cold waterD) by cold expressionE) by cooking with water

    33. The cake of ricinus seed left after expression is unfit for use as a cattle food since itcontains an extremely poisonous toxin known as ............................ .

    A) ricinin

    B) ricineC) taxolD) sinigrineE) lotaustralin

    34. Which of the following alkaloids derived from lysine?

    A) emetinB) chelidoninC) cinchonidinD) brucin

    E) lobelin

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    35. Which of the following drugs contains inulin?

    A) Cichoriae radixB) Comfrey rootC) Plantain shoot

    D) Foenigraeci semenE) Tanaceti herba

    36. Hasis (hashish) consists ........ of Cannabis sativa.

    A) gum of the male flowersB) resin of the female flowersC) gum of the male and female flowersD) pressed juice of the leavesE) latex of the tops

    37. What is Opium?

    A) Latex exudate of the unriped incised capsules after air dried.B) Dried wateric extract of the riped capsules.C) Dried alcoholic extract of the unriped capsules.D) Concentrated alcoholic extract of the poppy straw.E) Wateric extract of the riped seeds.

    38. The common base skeleton of physiologically active ergoline alkaloids is:

    A) isolysergic acid.B) clavorubine.C) lysergic acid.D) 2-phenylbenzopyrane.E) elimoclavine.

    39. Codeine is:

    A)monomethyl ether of morphine.B) amide of apomorphine.C) acetyl derivative of morphine.

    D) dimethyl ether of papaverine.E) diethyl ether of morphine.

    40. Skeleton of the B-type procyanidines is:

    A) flavan-3-ol.B) flavan-4-on.C) lignan.D) flavanolignan.E) flavanonol.

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    41. Select the method prescribed for quantitative determination of anthraglycosides inPharmacopoeia Hungarica Editio VII.:

    A) gravimetry.B) high pressure liquid chromatography.

    C) spectrophotometry.D) gaschromatography.E) titrimetry.

    42. Select the compound prescribed for quantitative determination on the base of complexformation in Pharmacopoeia Hungarica Editio VII.:

    A) bitter substance.B) flavonoid.C) alkaloid.D) saponin.

    E) phenolglycoside.

    43. Which of the following physico-chemical characteristics is correct for mucilages?

    A) foamingB) specific colourC) specific gravityD) viscosityE) refractive index

    44. Poppy straw is the industrial raw material of morphine production because .. .

    A) poppy straw contains only morphineB) poppy straw does not contain other alkaloidsC) poppy straw has the maximum morphine contentD) poppy straw is the chiepest available raw materialE) poppy straw contains morphine derivative

    45. Definition of vegetable drugs in the Pharmacopoeia:

    A) plant part used in medicine.

    B) plant part containing the highest content of the bioactive/characteristic compound/s.C) dried part of the medicinal plant.D) plant part or its preparations described in the paragraphs of the Pharmacopoeia.E) dried plant part used in medicine.

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    46. The whole in toto vegetable drugs of mild activity have to be rejected when ...

    A it contains any toxic foreign matter (plant parts).B) it contains foreign matter (plant parts) more than prescribed in the corresponding

    paragraph of the pharmacopoeia.

    C) it contains any toxic foreign matter (plant parts) which can not be separated.D) it contains any foreign matter (plant parts).E) it contains other parts of the plant more than prescribed in the corresponding

    paragraph of the pharmacopoeia.

    47. A vegetable drug is considered as one of pharmacopoeial quality, when:

    A) it meets both the general requirements of the pharmacopoeia and the requirementsof the corresponding paragraph in the pharmacopoeia.

    B) it meets the requirements of the corresponding paragraph in the pharmacopoeia.C) it meets the requirements of the national Standard I.

    D) it meets the general requirements of the pharmacopoeia.E) it meets both the general requirements of the pharmacopoeia and the requirements

    of the national Standard I.

    48. Which of the following statement is associated with the name of Jnos KABAY?

    A) Isolation of morphine.B) Structure elucidation of morphine.C) Industrial production of morphinanes from poppy straw.D) Industrial production of morphinanes from opium.E) Industrial production of morphinanes from unriped poppy capsules.

    49. Which of the following statement is associated with the name of Mikls BKSSY?

    A) Industrial production of essential oils by steam distillation.B) Industrial production of poppy alkaloids.C) Cultivation of ergot.D) Isolation of morphine.E) Production of ergot alkaloids by fermentation.

    50. Whose name of the followings is associated with the discovery of morphine?

    A) CaventouB) SertrnerC) StollD) PelletierE) Scheele

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    51. Select the method used for the fixed vegetable oil-preparation of pharmacopoeialquality:

    A) solvent extraction.B) expression.

    C) cold-expression.D) steam distillation.E) expression and solvent extraction.

    52. Quality control of medicinal plants is carried out by authority in Hungary:

    A) National Pharmaceutical Institute.B) any institute for quality control.C) Herbaria (National Medicinal Plant Trading Company).D) Hungarian Bureau of Standards.E) Research Institute for Medicinal Plants.

    53. Which of the following vegetable drugs has the highest caffeine content?

    A) Mate foliumB) Theae foliumC) GuaranaD) Coffeae semenE) Colae semen

    54. Which of the following cannabinoids is narcotic?

    A) cannabichromeneB) tetrahydrocannabinolC) cannabigerolD) cannabinolE) cannabidiol

    55. Select the vegetable drug which has the highest alkaloid content!

    A) Chinae succirubrae cortexB) Stramonii folium

    C) Ipecacuanhae radixD) Strychni semenE) Belladonnae radix

    56. Which of the following constituents is not present in Aetheroleum chamomillae?

    A) chamazuleneB) matricinC) spatulenolD) -BisabololE) en-in-dicycloethers

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    57. Which of the following constituents is not present in Chamomillae anthodium?

    A) chamazuleneB) matricinC) spatulenol

    D) -BisabololE) en-in-dicycloethers

    58. Which of the followings is true for inulin?

    A) arabinB) pectinC) galaktaneD) mannanE) fructosane

    59. Number of vegetable drugs which are not subject to restriction in Hungary?

    A) less than 50B) between 50 and 100C) between 100 and 300D) between 300 and 500E) more than 500

    60. Which of the followings is correct for the molecular mass of tannins?

    A) less than 200B) between 200 and 500C) between 500 and 1000D) between 1000 and 3000E) more than 3000

    61. Which of the following vegetable drugs is carminative?

    A) Frangulae cortexB) Centaurii herbaC) Silybi mariani fructus

    D) Foeniculi fructusE) Graminis rhizoma

    62. Which of the following vegetable drugs contains ajoene?

    A) Valerianae radixB) Agrimoniae herbaC) Echinaceae radixD) Ginseng radixE) Allii sativi bulbus

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    63. Which of the following plant constituents can be characterized by reversiblecomplexation with proteins?

    A) alkaloidsB) saponins

    C) tanninsD) mucilagesE) anthraglycosides

    64. Morphine content in Opium is:

    A) less than 0.5 %.B) between 0.5 and 1.0 %.C) between 1.0 and 5 %.D) between 5 and 10 %.E) between 10 and 15 %.

    65. Which of the following vegetable drugs contains aucubin?

    A) Marrubii herbaB) Agrimoniae herbaC) Valerianae rhizoma and radixD) Plantaginis foliumE) Cyani flos

    66. Which of the following vegetable drugs is in the category ofamara aromatica?

    A) Absinthii herbaB) Cardui benedicti herbaC) Gentianae radixD) Trifolii fibrini foliumE) Centaurii herba

    67. Hide powder is used in the traditional method of tannin quantitation because ...

    A) hide powder gives a colour reaction with tannin.B) hide powder reacts with polyphenols.

    C) hide powder reduces tannins.D) hide powder oxidizes polyphenols.E) hide powder reacts with tannins.

    68. What type of compound is arbutin used in urological infections?

    A) flavonoid glycosideB) phenolic glycosideC) furanocoumarinD) iridoid glycosideE) gallotannin

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    69. How can you extract tertiary alkaloids in the form of salts?

    A) Extracting with organic solvent like chloroform.B) Boiling with aqueous ammonia.C) Extracting with organic solvent containing alkaline solution.

    D)Extracting with organic solvent containing acidic solution.E) Extracting with an acidic aqueous solution.

    70. Ginseng saponins are of the ............... series

    A) lupaneB) ursaneC) abietaneD) oleananeE) dammarane

    71. Choose the right compound for the following structure:

    A) podophyllotoxinB) taxifolinC) silybinD) hyperosideE) silychrystine

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    2. Mult iple Choice

    The following questions have one or more correct answers. Use the notations given below:

    A: Only answer 1 is correctB: Only answer 3 is correctC: Only answers 1 and 5 are correctD: Only answers 2 and 3 are correctE: Only answers 2 and 4 are correct

    72. Choose the drugs which contain alkaloids derived from ornithine.

    1) Hellebori rhyzome2) Henbane leaf3) Cocae leaf4) Ribes nigri leaf5) Valeriana rhyzome

    73. Which statements are correct concerning with proazulens?

    1) Proazulens show orange spot on TLC by spraying with cc. ammonium hydroxyde.2) Proazulens give blue colour with EP reagent on heating.3) Proazulens give red colour on ninhydrine reagent.4) The proazulens transform into chamazulene by heating with mineral acid.5) The proazulens give yellow precipitate with resorcinole.

    74. The following properties are characteristic for saponins:

    1) They give precipitate by shaking with water.2) They are diterpenes.3) They cause haemolysis on erythrocytes.4) They give negative Keller-Kiliani test.5) They have usually acetic acid in their molecules.

    75. Which of the following properties are characteristic for tannins?

    1) They give precipitate on alkaloids.2) They give yellow or bluish-red color on iron-III-chloride.3) They are 3-phenylbenzopyrane-derivatives.4) They give pale pink precipitate on iodine.5) They transform the hide into leather.

    76. Choose the antraquinone containing drugs.

    1) Betulae folium2) Graminis rhyzome3) Rhei rhizome

    4) Herniariae herba5) Rubi ideae folium

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    77. Galenicals prepared from Cinchona bark are used as .............. .

    1) abortive2) bitter tonic3) stomachic

    4) cough reliever5) emetic

    78. Pilocarpin the alkaloid of Jaborandi folium has.................... .

    1) antagonist effect of atropin2) agonist effect of atropin3) sedative effect4) diuretic activity5) emetic activity

    79. Which of the following compounds are C-glycosides:

    1) arbutin.2) vitexin.3) gentiopicrine.4) aloin.5) hypericine.

    80. Choose the drugs containing purine derivatives.

    1) Capsicum fuictus2) Pasta guarana3) Colae semen4) Podophylum5) Pyrethri flos

    81. Choose the alkaloids derived from tryptophan.

    1) ephedrine2) chinin3) vinchrystin

    4) tomatidenol5) protoveratrin A

    82. The alkaloids of Ipecacuanha root have.....................effect.

    1) expectorant2) pain killer3) sedative4) antipyretic5) amoebicide

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    83. Opium is used in the medicine as............................... .

    1) tranquillant2) starting material for morphine production3) pain killer

    4) laxative5) emetic

    84. In the typical alkaloids N atom(s) derived from amino acid is/are present:

    1) in heterocyclic ring2) as ammonium cation3) as substituent of benzene ring4) as substituent of pyrane ring5) in their side chain

    85. Choose the plant species which are steroid sources for Industry.

    1) Licorice species2) Dioscorea composita3) Smilax regelii4) Ipomea purga5) Hydrastis canadensis

    86. Which are the most frequently occurring special sugars present in the cardioactiveglycosides?

    1) cymarose2) apiose3) xylose4) fucose5) digitoxose

    87. Choose the drugs which contain no cardioactive compounds.

    1) Thornapple leaf2) Lily of the valley shoot

    3) Oleandri folium4) Foxglove leaf5) Allii bulb

    88. The presence of alkaloid in plant material can be tested by the following reagents:

    1) 3,-dinitrobenzoic acid in NaOH (Kedde reagent).2) Potassium-mercury iodide solution (Mayer reagent).3) 2,4-dinitrophenylhydrazin solution.4) potassium bismuth iodine solution (Dragendorff reagent).5) aluminium trichloride in alcohol.

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    89. The alkaloids are grouped by the origin and position of nitrogen atom(s) as proto-,typical, and pseudo-alkaloids respectively. Choose the pseudo-alkaloids from thefollowings:

    1) protoveratrine B.

    2) pilocarpine.3) thebaine.4) ergocornin.5) capsaicine.

    90. Which statements are characteristic for the pentacyclic triterpenes from the followings:

    1) They were formed of farnezyl-pyrophosphate.2) In their structure(s) can be found usually unit(s) derived from loganine.3) At the carbon atom number 3 of the base structure has rarely oxo and hydroxyl

    groups respectively.

    4) They have usually low melting point.5) The pentacyclic triterpenes frequently occur in glycosidic and esther form as well.

    91. The alkaloids are present in plants in the form of........................ .

    1) mineral salt2) free basis3) salt of organic acid4) lactones of organic acid5) esther of mineral acid

    92. Choose the alkaloids derived from phenylalanine.

    1) tubocurarine2) toxiferin C3) theophyllin4) chinidine5) narcotine

    93. Which ones are correct from the following statements concerning with Opium?

    1) Opium is the dried latex obtained by incision from unripe capsule of Opium poppy.2) Opium is the dried juice of the cutting leaves of Opium poppy.3) Opium is the dried water extract of the shoot of Opium poppy.4) Opium with good quality has 1.5 % morphine content.5) Opium is used in the medicine as diuretics and laxative.

    94. Choose the right assay for determination of alkaloid content of drugs.

    1) azeotropic distillation2) photometry (in UV and visible light)3) gravimetry

    4) titration in non-aqueous media5) titration according to Volchards method

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    95. Choose of the following compounds which the Opium contains.

    1) chelidonin2) narceine3) hypericine

    4) narcotine5) heroin

    96. Which are of the following drugs having high ascorbic acid content?

    1) Hippopheae fruit2) Manna3) Agar4) Galliae odorati herba5) Rosa hips

    97. Which properties are characteristic for the starches?

    1) They can be dissolved in cold water very well.2) Starches form a jelly on boiling water.3) Starches give blue or green product on mineral acids.4) The starches turn the plane of the light polarization.5) Starches contain amino acids in a large amount.

    98. How to protect the drugs against the undesirable postmortal changing?

    1) Dry the plant material so quickly as soon as possible.2) Moistened the plant material with a calculated amount of water and keep it in a

    refrigerator.3) The plants are stored at a cold place in covered container.4) Put the plant material in a hermetically sealed container and kept it at room

    temperature.5) Stored the plant material in deep freezer at 18 oC.

    99. Which is the right reagent for identification of Ergot alkaloids?

    1) van Urk

    2) Fehling I and II3) iron-III-chloride4) phloroglucinol in hydrochloric acid5) EP test

    100. Choose the type of chemical structure of loganin.

    1) iridoid2) labdan type diterpene3) pseudoguaianolid4) abietane

    5) clerodan

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    101. What kind of type of compounds can be detected by Mayers reagent?

    1) sesterterpenes2) starches3) alkaloids

    4) procyanidines5) leucoanthocyanidins

    102. What are iridoids?

    1) Stress compounds characteristic for Lamiaceae family.2) Sesterterpenes with acrid taste.3) The iridoids are monoterpenes with cyclopentan-(c)-pyrane structure.4) Pseudoalkaloids.5) Iridoids are constituent of balms since they have a pleasant scent.

    103. The senna-emodin aglycones and senna-emodin glycosides are ....................derivatives.

    1) tetraterpenes2) monoterpenes with labdane structure3) anthraquinones4) pseudoguaianolides5) iridoids

    104. Which are the right reagents for the detection of cardioactive glycosides?

    1) Baljet reagent2) Hirschson reagent3) Benzidine in alcohol4) Froehde reagent5) Kedde reagent

    105. ..........................can be detected by Keller-Kiliani test.

    1) The aglycon of digitalis glycosides2) The digitoxose of digitalis glycosides3) The cymarose from the strophanthus glycosides

    4) Strophantidine5) Digitoxigenin

    106. Choose the plants which become valuable by fermentation.

    1) Calami rhyzome2) Gentian root and rhyzome3) Ratanhia root4) Theae leaf5) Lime flower

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    107. Choose the drugs which can quantify by photometry.

    1) Gentian root2) Cinchona bark3) Alder Buckthorn

    4) Nettle root5) Coriandri fructus

    108. Iridoids are highly oxygenated monoterpenes. They were named .............................

    1) after their black degradation products.2) after their blue color in acidic media.3) after an ant species Iridomirmex humilis since this type of compounds had been

    isolated from them.4) after their pleasant odor (fragrance) similar to Iris germanica.5) after an Irish scientists who discovered this type of component.

    109. The bitter value shows the .................... of an extract made of 1g drug which has justbitter taste.

    1) largest dilution2) lowest dilution3) smallest concentration4) largest concentration5) highest trituration

    110. Choose the volatile oils having higher density than the water.

    1) Aetheroleum menthae piperitae2) Aetheroleum cinnamomi3) Aetheroleum synapis synthetica4) Aetheroleum rosae5) Aetheroleum rosemarini

    111. Choose the right reagent for identify of Ipecacuanha root.

    1) EP reagent

    2) Froehde reagent3) 0.01N iodine in alcoholic solution4) chlorogen with diluted hydrochloric acid5) Behrens reagent

    112. Choose the active compounds of Hops.

    1) humulon2) cnicine3) loganin4) picrosalvine

    5) lupulon

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    113. Choose the homopolysaccharide containing drugs.

    1) Acacia gum2) Cotton3) Potato starch

    4) Agar5) Marsmallow leaf and root

    114. Choose of the following volatile oils having higher density than the water.

    1) Aetheroleum thymi2) Aetheroleum caryophylli3) Aetheroleum lavandulae4) Aetheroleum cinnamomi5) Aetheroleum pini pumilionis

    115. Which of the following alkaloid bases are liquids?

    1) morphine2) nicotine3) arecoline4) scopolamine5) chinine

    116. Select the compounds which are terpenoids!

    1) iridoids2) anthocyanins3) mucilages4) tannins5) carotenoids

    117. Which of the following alkaloids are bisindols, characteristic in Catharanthi herba?

    1) vincamine2) vincristine3) vinblastine

    4) catharanthine5) vindoline

    118. Which of the following saccharides are dideoxy hexoses, characteristic in cardiacglycosides?

    1) xilose2) diginose3) galactose4) digitoxose5) glucose

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    119. Select the vegetable drugs containing pseudoalkaloids!

    1) Chinae succirubrae cortex2) Veratri rhizoma3) Solani herba

    4) Secale cornutum5) Ephedrae herba

    120. Which of the following vegetable drugs contain sesquiterpene--lactones as bittercompounds?

    1) Absinthii herba2) Centaurii herba3) Marrubii herba4) Gentianae radix5) Cardui benedicti herba

    121. Select the vegetable drugs containing monoterpene bitter compounds!

    1) Absinthii herba2) Centaurii herba3) Marrubii herba4) Gentianae radix5) Cardui benedicti herba

    122. Which of the following vegetable drugs contain proazulenogenes?

    1) Chamomillae anthodium2) Coriandri fructus3) Menthae piperitae folium4) Melissae folium5) Cardui benedicti herba

    123. Select those essential oils which contain phenylpropanoids!

    1) Aetheroleum coriandri2) Aetheroleum foeniculi

    3) Aetheroleum lavandulae4) Aetheroleum cinnamomi5) Aetheroleum chamomillae

    124. Which of the following compounds are C-glycosides?

    1) aloin2) rutin3) hyperoside (Hyperin)4) lanatoside-C5) vitexin

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    125. Which of the following vegetable drugs contain galactans (polysaccharides of thegalactose).

    1) Lana gossypii2) Agar-agar

    3) Cichorii radix4) Carrageen5) Gummi arabicum

    126. Select the vegetable drugs with significant silicon content.

    1) Verbasci flos2) Pulmonariae herba3) Equiseti herba4) Lamii folium5) Tiliae flos

    127. Which of the following reactions are specific for alkaloids?

    1) Vitali-reaction2) Borntrger-reaction3) Kedde-reaction4) Liebermann-Burchard-reaction5) Marquis-reaction

    128. Which of the following reactions are specific for cardiac glycosides?

    1) Kedde-reaction2) Murexid-reaction3) Borntrger-reaction4) Vitali-reaction5) Legal-test

    129. Which of the following reactions are specific linked to the presence of the,-unsaturated--lactone?

    1) Liebermann-Burchard reaction

    2) Kedde-reaction3) Keller-Kiliani-reaction4) Legal test5) Xanthidrol-reaction

    130. Select the lysine-derived alkaloids from the following list!

    1) coniine2) pilocarpine3) strychnine4) tropine

    5) pseudopelletierine

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    131. Select the tryptophan-derived alkaloids from the following list!

    1) atropine2) quinine3) fcgonine

    4) strychnine5) quinolizidine

    132. Which of the following alkaloid-drugs play a significant world-wide role inpharmaceutical industry?

    1) Scopoliae herba2) Catharanthi herba3) Secale cornutum4) Vincae minoris herba5) Chelidonii herba

    133. Which of the following vegetable drugs contain cardenolide-glycosides?

    1) Crataegi summitas2) Hellebori rhizoma3) Convallariae herba4) Crataegi fructus5) Scillae bulbus

    134. Which of the following vegetable drugs contain bufadienolide-glycosides?

    1) Scillae bulbus2) Convallariae herba3) Digitalis lanatae folium4) Oleandri folium5) Hellebori rhizoma et radix

    135. Which of the following alkaloids are quaternary?

    1) berberine2) bhelidonine

    3) vincamine4) brucine5) C-toxiferine

    136. Select the vegetable drugs with significant rutin (rutoside) content!

    1) Fagopyri herba2) Liquiritiae radix3) Hyperici herba4) Aurantii pericarpium5) Sophorae japonicae flos

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    137. Which of the following natural compounds are non-steroid antiinflammatory agents?

    1) azulene2) arbutin3) scopoletin

    4) primulic acid5) aescin (escin)

    138. What type of compounds are formed through acid catalysed decomposition ofprocyanidins?

    1) flavanone2) catechin3) flavonol4) anthocyanidine5) chalkone

    139. Which of the followings are characteristic for the alkaloid extractor official inPharmacopoeia Hungarica Editio VII.?

    1) Both solid/liquid and liquid/liquid extraction take place.2) Extraction takes place at high temperature.3) It works with organic solvent heavier than water.4) It works with organic solvent either heavier or lighter than water.5) It utilizes the differences in solubility of alkaloid bases and their salts in organic and

    wateric phases respectively.

    140. Which of the following natural substances serve as starting material in thesemisynthesis of pregnenolone acetate?

    1) oleanolic acid2) diosgenin3) lanatozide-C4) phytosterols5) jervine

    141. Which of the following methods are not suitable for the detection of matricin in

    Chamomillae anthodium?1) Extraction followed by UV spectroscopy.2) High pressure liquid chromatography.3) IR spectroscopy.4) Extraction chromatography.5) Specific test - tube test.

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    142. Select those vegetable drugs which contain fructosanes!

    1) Cichoriae radix2) Salep tuber3) Althaeae radix

    4) Saponariae albae radix5) Graminis rhizoma

    143. Which of the following medicinal plants are important for pharmaceutical industry?

    1) Equisetum arvense2) Catharanthus roseus3) Salvia officinalis4) Papaver somniferum5) Digitalis purpurea

    144. Which of the following vegetable drugs are important for pharmaceutical industry?

    1) Digitalis lanatae folium2) Digitalis purpureae folium3) Tiliae flos4) Rutae herba5) Sophorae japonicae flos

    145. Which of the following vegetable drugs are official in the Hungarian PharmacopoeiaEditio VII.?

    1) Secale cornutum2) Belladonnae folium3) Melissae folium4) Digitalis lanatae folium5) Digitalis purpureae folium

    146. Which of the following vegetable drugs are not official in the HungarianPharmacopoeia Editio VII.?

    1) Crataegi summitas

    2) Catharanthi herba3) Digitalis lanatae folium4) Ratanhiae radix5) Primulae radix

    147. Select those vegetable drugs which are used as amara aromatics!

    1) Absinthii herba2) Gentianae radix3) Tiliae flos4) Cynarae folium

    5) Calami rhizoma

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    148. Marshmallow root and deadly nightshade root can be distinguished by microscopy onthe base of:

    1) the form of Calcium oxalate crystals.2) the position and arrangement of Calcium oxalate crystals.

    3) the absence or presence of scleroids.4) the absence or presence of Calcium oxalate crystals.5) the absence or presence of bands of fibres.

    149. Which of the following vegetable drugs contain active compounds used in cardiacinsufficiency?

    1) Rauwolfiae radix2) Crataegi summitas3) Convallariae herba4) Chinae cortex

    5) Vincae minoris herba

    150. Select those vegetable drugs which contain laxative agents!

    1) Sennae fructus2) Hyperici herba3) Urticae radix4) Equiseti herba5) Agrimoniae herba

    151. Which of the following vegetable drugs contain indole alkaloids?

    1) Veratri rhizoma2) Colchici semen3) Catharanthi herba4) Chinae succirubrae cortex5) Arecae semen

    152. Select those vegetable drugs which have sulphur containing active ingredients!

    1) Echinaceae radix

    2) Tropeoli herba3) Ginseng radix4) Allii sativi bulbus5) Urticae radix

    153. Which of the following vegetable drugs have significant vitamin content?

    1) Hippopheae pseudofructus et semen2) Hippocastani semen3) Sinapis albae semen4) Centaurii herba

    5) Cynosbati pseudofructus

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    154. Conii fructus can be distinguished from Anisi vulgaris fructus by microscopy on thebase of:

    1) Conii fructus has secretion (essential oil) ducts.2) there are no trichomes on Conii fructus.

    3) Anisi vulgaris fructus has no secretion (essential oil) ducts.4) Conii fructus has no secretion (essential oil) ducts.5) non of them contain aleurones.

    155. Which of the following vegetable drugs contain carvone in the essential oil?

    1) Menthae crispae folium2) Anisi vulgaris fructus3) Coriandri fructus4) Menthae piperitae folium5) Carvi fructus

    156. Select the vegetable drugs with significant carotinoide content!

    1) Capsici fructus2) Papaveris rhoeados flos3) Cyani flos4) Malvae flos5) Hippopheae pseudofructus

    157. Which of the following reactions serve as possibilities in the detection of quinolinealkaloids?

    1) Vitali reaction2) Thalleiochin reaction3) Murexid reaction4) Vogel reaction5) Keller-Kiliani reaction

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    3. Grouping

    158. Mark letter A after the tumor inhibiting and letter B after the bitter tonic containing

    drugs.

    1) Marrubii herba2) Catharanthi herba3) Podophyllum4) Colocynthidis fructus5) Calamus6) Cinchona bark7) Centaurii herba8) Absinthii folium

    159. Mark letter A after bufadienolides and letter B after cardenolides containing drug.

    1) Foxglove leaf2) Black Hellebore rhyzome3) Strophanthus seed4) Digitalis lanata leaf5) Oleander leaf6) Squill7) Lily of the valley

    160. Mark letter A after the active principles of Gentian root and letter B after the activeprinciples of Valerian rhyzome.

    1) swertiamarine2) valerenic acid3) didrovaltrate4) amaropanin5) sweroside6) gentianose7) bornyl-isovalerianate8) amarogentin

    161. Mark letter A after the unsaturated and letter B after the saturated fatty acids.

    1) myristic acid2) arachidic acid3) oleic acid4) ricinoleic acid5) linolenic acid6) palmitic acid

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    162. Choose the right medical uses of the following drugs:

    1) Kamala A. spasmolytic2) Ipecacuanha root B. anthelminthic3) Silybum fruit C. anti-inflammatory

    4) Rhubarb D. expectorant5) Chamomile flowers E. laxative6) Trifolii fibrini folium F. liver protector

    163. Choose the right test for the following alkaloids:

    1) Vitali A. morphine2) Murexide B. strychnine3) Thalleioquin C. ergotoxine4) van Urk D. quinine5) Marquis E. caffeine

    F. hyoscyne

    164. Complete the following sentence:

    Opium is ....................(A), which is obtained by incision of the ................(B) Opiumpoppy capsula.

    (A) (B)

    1) latex A. ripe2) mucilage B. unripe3) dried extract C. ripe and unripe4) dried resine D. turned brown in color5) dried juice E. turned blue in color

    165. Choose the right drug for the following compounds:

    1) loganine A. Cannabis indicae herba2) tetrahydro-cannabinol B. Ergot3) scopoletin C. Strychi semen4) clavorubine D. Catharanthi herba

    5) vinblastin E. Deadly night shade leaf6) porfiroxine

    166. Choose the hydrolisable A and the condensed B tannin containing drugs:

    1) Rhatany root2) Tormentillae rhyzome and radix3) Cinchona bark4) Oak bark5) Galls6) Rhubarb

    7) Catechu8) Cotini folium

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    167. Mark letter A after the active principles of Senna leaf and letter B after the activecompounds of Frangulae cortex.

    1) tinnevellin2) frangulin

    3) rheum-emodin4) palmidin C5) alo-emodin6) glycofrangulin7) sennidin C8) hypericin

    168. Which are the right test for identification of the following drugs?

    1) Frangulae cortex A. Murexide2) Foxglove leaf B. Vitali

    3) Ipecacuanha root C. Borntreger4) Acacia gum D. Froehde5) Deadly night shade leaf E. Baljet

    F. Benzidine

    169. Choose the right skeleton for the following components:

    1) bis-benzyl-isoquinoline A. matricine2) strychnine B. eugenol3) purine C. tubocurarine4) phenyl-propane D. toxiferin C5) guaianolide E. theobromine6) steran F. thebain7) morphinan G. loganin8) iridoid

    170. Choose the right components for the following drugs:

    1) Chamomile flower A. linamarine2) Linseed B. amaropanin3) Aetheroleum eucalypti C. alpha-bisabolol

    4) Gentian root D. cineol5) Balsamum peruvianum E. cinnameine6) Cod liver oil

    171. What are the right test for identification of these drugs:

    1) Bate-Smith test A. Acacia2) phloroglucinol test B. Rosa hips3) Fehling test C. Howthorn twig4) benzidine test D. Foxglove leaf5) Baljet test E. Benzoe siamese

    6) EP test F. Matricaria7) vanilline detection

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    172. What are the medical uses of the following drugs?

    1) Gentian root A. diaphoretic2) Balsamum peruvianum B. demulcent3) Marshmallow root C. antiseptic

    4) Lime flower D. laxative5) Linseed E. antipyretic

    173. Group these alkaloids by their parent amino acids.

    1) papaverine A. tryptophane2) ephedrine B. lysine3) vinblastine C. phenyl-alanine4) emetin D. ornithine5) hyoscyne E. thyrosine6) solanidine F. dopa

    7) lobeline

    174. Group the following drugs by their medical uses:

    1) Matricaria flowers A. expectorant2) Licorice root B. cardiotonic3) Lily of the valley shoot C. bitter tonic4) Colophony D. anti-inflammatory5) Gentian root E. sedative6) Valerian rhizome

    175. Mark letter A after the pentacyclic and letter B after the tetracyclic (steroidal) saponincontaining drugs.

    1) Foxglove leaf2) Ginseng root3) Quillaia bark4) Senegae radix5) Licorice root6) Sarsaparillae radix

    176. Mark letterA

    after narcotics and letterB

    after cardioactive drugs.1) Squill2) Khat3) Indian hemp4) Strophanthus seeds5) Poppy capsule6) Coca leaf7) Lily of the valley leaf8) Erysimi herba

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    177. Mark letter A after the sesquiterpene and letter B after the flavonoid type compounds.

    1) achilline2) apiin3) bisabolol

    4) cnicine5) luteolin6) xanthotoxine7) kempferol8) silydianine

    178. Choose the right compound for the following drugs:

    1) Cinnamon bark A. lobeline2) Calami rhizome B. cinchonidine3) Indian tobacco shooth C. acoron

    4) Caraway fruit D. dihydro-carveol5) Cinchona bark E. linalyl-acetate

    179. Which drug is used as stomachic A and which one as expectorant B ?

    1) Cardui benedicti herba2) Cowslip root3) Hederae herba4) Trifolii fibrini folium5) Thyme6) Centaurii herba7) Absinthii herba8) Ipecacuanha root

    180. Choose the right structure for the following skeleton:

    1) vincamine A. benzyl-isoquinoline2) hesperetin B. flavanone3) cinchonidine C. pseudo-guaianolide4) papaverine D. eburnan

    5) farnezol E. rubanol181. Choose the right compounds for the following drugs:

    1) Cannabis indicea herba A. cathinon2) Psylocybe B. THC3) Khat C. psylocibine4) Opium D. lysergic acid5) Ipomeae semen E. mescaline

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    186. Choose the right reagent for the identification of the following drugs:

    1) EP A. Rosa hips2) van Urk B. Acacia gum3) iron-II-sulphate with sodium-hydrocarbonate C. Capsicum

    4) phloroglucinol dissolved in ether D. Yarrow herba5) benzidine in spirits E. Ergot

    187. Mark letter A after the chemical constituents of Garlic and letter B after the chemicalconstituents of Onion.

    1) alliin2) allicine3) diallyl-disulphide4) ajoen5) cepaen

    6) cwibelane

    188. Match the vegetable drugs with their medicinal use.

    1) Uvae ursi folium A. antirheumatic2) Rosmarini folium B. antiseptic3) Balsamum peruvianum C. antipyretic4) Spireae herba D. urodisinfecting5) Equiseti herba

    189. Mark letter A after the Ginkgo biloba and letter B after the Arnicae flos constituents.

    1) bilobetin2) helenalin3) bilobalide4) amentoflavone5) miricetin-3-rutoside6) luteolin-7-glucoside7) cinarin8) polyacetylene

    190. Match the vegetable drugs with their characteristic constituents.

    1) 6-hydroxy-musizine A. clove2) hypericin B. spearmint3) gossypol C. cotton plant4) carvone D. senna5) and pinene E. ipecacuanha6) eugenol F. Saint John's wort

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    191. Mark letter A after the unsaturated and letter B after the saturated fatty acids.

    1) myristic acid2) erucic acid3) stearic acid

    4) linoleic acid5) melissic acid6) arachidonic acid7) oleic acid

    192. Match the vegetable drugs with their reactions.

    1) Mate herba A. Borntrger reaction2) Scopoliae radix B. Carr-Price reaction3) Senegae radix C. Vitali reaction4) Oleum jecoris D. Murexid reaction

    5) Foliculi sennae E. Liebermann-Burchard reaction6) Catechin F. Bensidine (alcoholic) reaction

    193. Mark letter A after vegetable drugs from which alkaloids are preferably extracted assalts and letter B after vegetable drugs from which alkaloids are preferably extracted asbases.

    1) Strychni semen2) Chinae cortex3) Stramonii folium4) Ipecacuanhae radix5) Chelidonii herba6) Secale cornutum

    194. Mark letter A after constituents of Lichen islandicus and letter B after constituents ofEchinaceae radix.

    1) protocetraric acid2) cetraric acid3) echinolone4) fumarprotocetraric acid

    5) protolichesteric acid6) echinocoside

    195. Match the alkaloids with their precursor amino acids.

    1) licapsamine A. phenylalanine2) chelidonine B. tryptophan3) reserpine C. glycine4) caffeine D. lysine5) sparteine E. ornithine6) aconitine

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    196. Match the plant constituents with their structures.

    1) vincamine A. purine2) brucine B. strychnane3) quinidine C. rubanol

    4) theophylline D. eburnanE. lysergol

    197. Match the vegetable drugs with their medicinal use.

    1) Lupuli strobuli A. laxative2) Veratri rhizoma B. antidiabetic3) Phaseoli legumen C. antihypertensive4) Anserinae herba D. sedative5) Tilliae flos E. adstringent

    198. Mark letter A after the constituents of Gentianae radix and letter B after the constituentsof Silybi mariani fructus.

    1) silydianin2) amaropanin3) silychristin4) swertiamarin5) silyhermine6) gentiopicroside7) amaroswerin8) sinigrine

    199. Match the vegetable drugs with their characteristic constituents.

    1) lynalyl acetate A. Petasidis folium2) bisabolol oxide B. Pyrethri flos3) arciin C. Bardanae radix4) senkirkine D. Coriandri fructus5) cinerine I. E. Chamomillae romanae flos

    200. Match the Latin names of plant parts with their English names.

    1) bulbus A. branch2) fructus B. fruit3) stipes C. top4) summitas D. bulb5) tuber E. tuber6) radix

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    207. Match the plant constituents with the structures.

    1) apigenin A. purine2) protoveratrin B. guaianolide3) caffeine C. flavone

    4) matricin D. cevaneE. rubane

    208. Match the plant constituents with the structures.

    1) papaverine A. tropane2) narcotine B. morphinane3) thebaine C. protopine4) cryptopine D. benzylisoquinoline

    E. ftalideisoquinoline

    209. Match the pharmaceutical preparations with the vegetable drugs.

    1) Vinblastin inj. A. Digitalis lanatae folium2) Legalon B. Sennae folium3) Isolanid C. Catharantri herba4) Tisasen A+B D. Silybi mariani fructus5) Ergometrin inj. E. Secale cornutum6) Rutascorbin

    210. Mark number 1 after amides of lysergic acid and number 2 after ergopeptines.

    A. ergocristineB. ergocornineC. ergotamineD. ergocryptineE. ergometrineF. ergosine

    211. Match the plant constituents with their chemical groups.

    1) procyanidine B-2 A. flavonoid

    2) khelline B. triterpene3) hyperoside (hyperine) C. -chromone4) oleanolic acid D. flavane5) scillaren A E. phenylpropane

    F. bufadienolide

    212. Match the vegetable drugs with their medicinal use.

    1) Uvae ursi folium A. laxative2) Carvi fructus B. immunostimulant3) Ginseng radix C. carminative

    4) Echinaceae radix D. adaptogenic5) Sennae fructus E. urodisinfecting6) Gentianae radix

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    217. Match the structures with their names.

    1) digitoxine

    2) lanatoside C

    3) purpurea glycoside A

    4) digoxine

    5) dezacetyl-lanatoside C

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    4. Relat ion analysis

    Your task is to analyse two sentences. The first is a statement, and the second is an explanation

    or a consequence.

    You have to decide whether both sentences are true or not, and whether any logical connectionexists between them or not.

    Here are five possibilities (A-E) but only one is true.

    A. Both the statement and the explanation or consequence are true, and a causal relationexists between them.

    B. Both the statement and the explanation or consequence are true, but there is no logicalrelation between them.

    C. The statement is true, but the explanation or consequence is false.D. The statement is false, but the explanation or consequence is true.E. Both the statement and the explanation or consequence are false.

    218. The fats become rancid hardly because fats are triglycerides involving long chainsaturated and the unsaturated acids.

    219. The monosaccharides may exist either as a five- or six-members ring, because theglucose has an aldehyde group while the fructose has a keto group.

    220. Dextrose is a sugar usually obtained by the hydrolysis of starch since the starch is builtup from alfa-D-glucopyranose units.

    221. The shape of the grain of different starches is characteristic for the plant derived from,because the starches are secondary metabolites of the plants.

    222. The starches cant be separated completely from the plant material because the starchesare insoluble in cold water.

    223. The first name of the plants denotes the genus while the second name denotes thespecies because we use the binomial system of Linnaeus.

    224. Pharmacognosy may not be defined as an applied science although it deals with thebiologic, biochemical and economic feature of natural drugs and their constituents.

    225. Procyanidines consist of trimeric isoflavanon units because the biogenesis of thesecompounds take place via geranyl-pyrophosphate route.

    226. Anthraquinone derivatives have N atom in their molecule, therefore the anthraquinoncontaining drugs are used as expectorant.

    227. Kamala is used in veterinary as vermicide since the drug contains tetraterpenes andaminoalcohols.

    228. Quillaia bark is used in the treating of essential hypertension because it contains

    ajmalin as chief glycoside.

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    261. Scopolamine is a true alkaloid because the precursor amino acid in scopolaminebiosynthesis is phenylalanine.

    262. The ricine toxalbumine is only dissolved in cold oil therefore Oleum ricini is preparedby cold expression.

    263. Solanaceae leaf contamination in Althaeae folium can not be distinguished by chemicalreactions because both vegetable drugs contain alkaloids.

    264. Morphine can be separated from the associate alkaloids in alcaline medium (pH 9-9.5)because the associate alkaloids are dissolved as phenolates.

    265. Hungarian Pharmacopoeia Editio VII. does not control Sambucus ebulus L. (dwarfelder) adulteration in Sambucus niger L. because Sambucus ebulus L. is a toxic plant.

    266. Atropine and cocaine can not be distinguished by Vitali reaction because both alkaloids

    have ecgonine skeleton.

    267. Atropine and scopolamine can not be distinguished by Vitali reaction because bothalkaloids have tropic acid in their structure.

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    5. Answer keys

    1.A2.A3.A4.C5.D6.C7.C8.D9.C10.C11.E12.D13.D14.B15.B16.C17.B18.C

    19.D20.D21.C22.B23.A24.E25.D26.C27.C28.D29.C30.D31.D32.D33.B34.E35.A36.B

    37.A38.C39.A40.A41.C42.B43.D44.D45.D46.C47.A48.C49.C50.B51.C52.E53.B54.B

    55.A56.B57.A58.E59.C60.D61.D62.E63.C64.E65.D66.A67.E68.B69.E70.E71.C

    72.D73.E74.B75.C76.B

    77.D78.A79.E80.D81.D82.C83.D84.A85.D86.C87.C88.E89.A

    90.C91.D92.C93.A

    94.E95.E96.C97.E98.C

    99.A100.A101.B102.B103.B104.C105.D106.E107.D108.B109.A110.D111.E

    112.C113.D114.E115.D

    116.C117.D118.E119.D120.C

    121.E122.A123.E124.C125.E126.D127.C128.C129.E130.C131.E132.D133.B

    134.C135.C136.C137.A

    138.E139.C140.E141.A142.C

    143.E144.C145.D146.D147.C148.C149.D150.A151.B152.E153.C154.E155.C

    156.C157.E

    158.1.B158.2.A158.3.A158.4.A158.5.B

    158.6.B158.7.B158.8.B159.1.B

    159.2.A159.3.B159.4.B159.5.B159.6.A

    159.7.B160.1.A160.2.B160.3.B

    160.4.A160.5.A160.6.A160.7.B160.8.A

    161.1.B161.2.B161.3.A161.4.A

    161.5.A161.6.B162.1.B162.2.D162.3.F

    162.4.E162.5.C162.6. 162. .A

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    163.1.F163.2.E163.3.D163.4.C163.5.A163. .6163. B164.1.A164.B.B165.1.C165.2.A165.3.E165.4.B165.5.D165.6. 166.1.B166.2.B166.3.B166.4.A166.5.A

    166.6.A166.7.B166.8.A167.1.A167.2.B167.3.B167.4.A167.5.A167.6.B167.7.A167.8. 168.1.C168.2.E

    168.3.D168.4.F168.5.B168. .A169.1.C169.2.D169.3.E169.4.B169.5.A169.6. 169.7.F169.8.G170.1.C

    170.2.A170.3.D170.4.B170.5.E170.6. 171.1.C171.2.E171.3.B171.4.A171.5.D171.6.F172.2.C172.3.B

    172.4.A172.5.D172. .E172.1.

    173.1.E173.2.C173.3.A173.4.F173.5.D173.6. 173.7.B174.1.D174.2.A174.3.B174.4. 174.5.C174.6.E175.1.B175.2.B175.3.A175.4.A175.5.A175.6.B176.1.B

    176.2.A176.3.A176.4.B176.5.A176.6.A176.7.B176.8.B177.1.A177.2.B177.3.A177.4.A177.5.B177.6.B

    177.7.B177.8.B178.1. 178.2.C178.3.A178.4.D178.5.B178. .E179.1.A179.2.B179.3.B179.4.A179.5.B

    179.6.A179.7.A179.8.B180.1.D180.2.B180.3.E180.4.A180.5. 180. .C181.1.B181.2.C181.3.A181.4.

    181.5.D181. .E182.1.A182.2.B

    182.3.A182.4.A182.5.A182.6.B182.7.B183.1.B183.2.A183.3.A183.4.A183.5.B183.6.B183.7. 184.1. 184.2. 184.3.A184.4.A184.5.A184.6.B184.7.B185.1.A

    185.2.B185.3.A185.4.B185.5.B185.6.B185.7.B185.8.A186.1.D186.2.E186.3.A186.4. 186.5.B186. .C

    187.1.A187.2.A187.3.A187.4.A187.5.B187.6.B188.1.D188.2.A188.3.B188.4.C188.5. 189.1.A189.2.B

    189.3.A189.4.A189.5.A189.6.B189.7.B189.8.B190.1.D190.2.F190.3.C190.4.B190.6.A190. .E191.1.B

    191.2.A191.3.B191.4.A191.5.B

    191.6.A191.7.A192.1.D192.2.C192.3.E192.4.B192.5.A192.6. 192.F. 193.1.B193.2.A193.3.A193.4.B193.5.A193.6.A194.1.A194.2.A194.3.B194.4.A194.5.A

    194.6.B195.1.E195.2.A195.3.B195.4.C195.5.D195.6. 196.1.D196.2.B196.3.C196.4.A196. .E197.1.D

    197.2.C197.3.B197.4.E197.5. 197. .E198.1.B198.2.A198.3.B198.4.A198.5.B198.6.A198.7.A198.8.

    199.1.D199.3.C199.4.A199.5.B199.2. 199. .E200.1.D200.2.B200.3.C200.4.A200.5.A200.6. 201.1.D

    201.2.A201.3.E201.4.B201.5.C

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    201.6. 202.1.B202.2.A202.3.A202.4.A202.5.A203.1.E203.2.A203.3.D203.4.C203.5.B204.1. 204.2.C204.3.B204.4.A204.5.D205.1.C205.2.A205.3.B205.4.D

    205.5.

    206.1.D206.2.A206.3.B206.4.C206. .E207.1.C207.2.D207.3.A207.4.B207. .E208.1.D208.2.E208.3.B208.4.C209.1.C209.2.D209.3.A209.4.B209.5.E209.6.

    210.2.A

    210.2.B210.2.C210.2.D210.1.E210.2.F211.1.D211.2.C211.3.A211.4.B211.5.F211. .E212.1.E212.2.C212.3.D212.4.B212.5.A212.6. 213.1. 213.2.B213.3.C

    213.4.E

    213.5.A213.6.D214.1.E214.2.A214.3.D214.4.C214.5.B214.6. 216.1.B216.2.A216.3.D216.4.C216.5.E217.1.E217.2.C217.3.A217.4.B217.5.D

    218.D219.B220.A221.C222.D223.A224.D225.E226.E227.C228.E229.A230.C

    231.A232.A233.B234.B235.D236.C237.C238.C239.C240.C241.E242.E243.D

    244.B245.E246.E247.E248.C249.D250.B251.A252.D253.B254.B255.A256.A

    257.A258.C259.B260.A261.C262.D263.E264.C265.D266.C267.A