ESPEN Congress Geneva 2014 LLL LIVE COURSE: NUTRITION IN ... · Nutrition in obesity •...
Transcript of ESPEN Congress Geneva 2014 LLL LIVE COURSE: NUTRITION IN ... · Nutrition in obesity •...
ESPEN Congress Geneva 2014LLL LIVE COURSE: NUTRITION IN OBESITY
Pre-operative medical assessment, post-operative follow-up and clinical outcome in bariatric surgery patientsA. Thorell (SE)
Nutrition in obesity• Pre-operative medical assessment, post-
operative follow-up and clinical outcome in bariatric surgical patients
Anders Thorell MD, PhD• Karolinska Institutet & Department of
Surgery, Ersta Hospital
Stockholm, Sweden
Ethical dilemmasBioethical principlesApplication of bioethical
principles to “Nutrition at the end-of-life”
The decision-making process
Outline
• Treatment modalities• Indications for bariatric surgery• Bariatric surgical procedures• Preoperative assessement• Postop follow-up• Clinical outcome
Obesity - Treatment modalities
• Diet regimens• Behavioural therapy • Physical activity• Pharmacological• Surgical (Bariatric surgery)
Bariatric surgery- indications
• BMI > 40 kg/m2 or• BMI > 35 kg/m2 with comorbidity• Earlier ”serious” weight-reducing attempts• No major eating disorders
– BED (Binge eating disorder)– AN (Anorexia nervosa)
• Well informed• Well motivated
Bariatric surgical procedures
• Restrictive– Vertical banded gastroplasty– Adjustable gastric banding– Sleeve gastrectomy– Gastroplication
• Malabsorptive– Biliopancreatic diversion– Biliopancreatic diversion with duodenal
switch
• Combined– Roux-en-Y gastric bypass
Vertical banded gastroplasty
Adjustable Gastric Banding
Sleeve resection
Gastroplication
11
Gastroplication
12
Biliopancreatic diversion
Biliopancreatic diversion with duodenal switch
Roux-en-Y Gastric bypass
Bariatric procedures trends
Buchwald & Oien, Obes Surg 2013
010203040506070
2003 2008 2011
% p
roce
dure
s
Gastric Band
Gastric Bypass
Sleeve Gastrectomy
BPD/DS
Mini GB
Worldwide: 146 000 344 000 340 000Europe: 33 000 67 000 113 000
Preoperative assessment
• Aim to ensure that:
• Comorbidities are identified and optimized• Patients are well informed regarding:
– Expected outcome/risks– Importance of adherence to postop regimens
• Well motivated and willing
Preoperative assessment
• Multidisciplinary team:
• Bariatric surgeon• Internist• Anaesthesist• Dietician• Specialist nurse• Psychologist/Psychiatrist
Preoperative assessment
• General
• Identify risk factors that increase risk:• Cariovascular
– Iscaemic heart disease– Thromboembolic events– Unregulated hypertension
• Metabolic disease (diabetes)• Previous surgery (adhesions)
Preoperative assessment
• Procedure specific:
• RYGB– Inflammatory Bowel Disease– Premalignant gastric conditions– H.Pylori
• Sleeve gastrectomy– Gastroesophageal reflux disease
Postoperative Follow-up- Complications
• Early – Postoperative complications
• Anastomotic leak• Bleeding• Infections• Thromboembolic events
• Late– Complications
• Internal herniation• Stomal ulcers
– Chronic pain– Nutitional deficiencies
Early complications (< 1 week)
• Symptoms– Abdominal pain– Tachycardia– Fever– Nausea/vomiting– Respiratory distress
• Actions– Blood sampling– Upper endoscopy– Radiology– Immediate surgical intervention
Long term follow up
• 6 weeks, 6 months, annually– Athropometrics– Blood sampling– Prescription of supplementation:
• Multivitamin• Cobolamine (Vitamin B12)• Calcium Citrate• Vitamin D• Iron (Menstruating women)
• Councelling– Dietary– Lifestyle
Long term follow up
• Procedure specific– Band Adjustment (AGB)– VBG, Sleeve: only multivitamin supplementation– Malabsorptive: More extensive laboratory checks
• Outcome dependent on adherence tofollow-up!
Outcome after bariatric surgeryWeight (SOS)
Sjöström L et al. NEJM 2007
Outcome after bariatric surgeryDiabetes incidence (SOS)
Sjöström L et al NEJM 2004;351:2683-2693
Odds ratio: 0.14 0.2595% CI: 0.08 - 0.24 0.17 - 0.38N control 1402 539N surgery 1489 517
Outcome after bariatric surgeryDiabetes remission (SOS)
Sjöström L et al NEJM 2004;351:2683-2693
Outcome after bariatric surgeryHbA1c (Randomized)
Schauer et al NEJM 2014
Outcome after bariatric surgeryCardiovascular disease (MI)
Schauer et al NEJM 2014
HR = 0.71595% CI: 0.518 to 0.987
P= 0.0411
-28.5%Individualswith MI, n
Control 87Surgery 64
0
2
4
6
8
Cum
ulat
ive
inci
denc
e, %
0 2 4 6 8 10 12 14 16Years of follow up Sjöström et al NEJM 2006
Outcome after bariatric surgery- Mortality (SOS)
HR = 0.71595% CI: 0.518 to 0.987
P= 0.0411
-28.5%
0
2
4
6
8
0 2 4 6 8 10 12 14Years of follow up
Sjöström L et al NEJM 2004;351:2683-2693
Outcome after bariatric surgery- Kidney function
HR = 0.71595% CI: 0.518 to 0.987
P= 0.0411
0
2
4
6
8
0 2 4 6 8 10 12Years of follow up
Iaconelli et al. Diabetes Care 2011
Summary
• Volumes of bariatric surgery increasing• Effects on:
– Weight– Co-morbidities– Quality of life– Mortality
• Invasive procedures (risks) • Pre- and postop assessment crucial• Life-long follow up mandatory