DAY 2 - Inflam and Immuno 2

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    Treating Cholera

    Sack, David, et al . 2004. Seminar: Cholera. The Lancet. 363: 223-233.

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    Epidemic Control Measures

    Hygienic disposal of human wasteAdequate supply of waterGood food hygiene

    Thoroughly cooking food Eating food while its hot Preventing cooked foods from contacting

    raw foods (including water or ice) Avoiding raw fruits or vegetables Washing hands after defecation & before cooking

    http://www.who.int/mediacentre/factsheets/fs107/en/print.html

    Sack, David, et al. 2004. Seminar:Cholera. The Lancet. 363: 223-233.

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    DEFINITIONLeptospirosis is a kind of zoonotic

    infectious disease caused by pathogenic

    leptospires;rats and swine are cardinal sourceof infection.

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    Causative Agent: Bacteria of theGenus Leptospira

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    DEFINITION clinical features:

    three symptoms,

    three signs,internal organ damage,seguelae of eyes and nerve system

    treatment : penicillin.

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    Routes of transmission:(1) water borne (indirect contact

    transmission):

    by skin, mucosa, when skin is injured.(2) direct contact transmission:(3) food borne

    PATHOGENESIS

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    PATHOGENESISleptospira

    skin, mucosaInitial stage leptospiremia ( toxic symptoms)(1~3days) three symptoms :

    fever,myalgia,headachethree signs:conjunctival suffussion;

    muscle tenderness;

    enlargement of thelymphnodes

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    PATHOGENESISsevere toxic symptoms

    lesion of organs:- influenza form

    - pneumorrhagic formmiddle stage - icterohemorrhagic form(3~10d) - meningoencephalitis

    renal failure form.

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    Leptospirosis

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    Diagnostic test:

    1.MAT (Microscopic Agglutination Test)

    2.ELISADrugs:1.Oral doxycycline2.Ampicillin3.Streptomycin4.Intravenous Penicillin G

    Leptospirosis

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    Leptospirosis

    Health Teachings1.Provide education to clients telling them toavoid swimming in potentially contaminatedwater or flood water.2. Use of proper protection like boots, gloves

    when work requires exposure to

    contaminatedwater.3. Drain potentially contaminated water when

    possible.

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    Leptospirosis

    Nursing Management1. Isolate the patient and concurrentdisinfection

    of soiled articles.2. Report all cases of leptospirosis.

    3. Investigation of contacts and source of infection.

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    PATHOGENESIS

    immunopathological reaction after fever; sequelae of eyes; reactive meningitis; cerebro arteritis obliterans. convalescent stage

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