Curriculum Vitae

Joel D. Baines, VMD PhD

Skip Bertman Drive

Office of the Dean

Louisiana State University School of Veterinary Medicine Baton Rouge, LA

Telephone: (225) 578-9903

Email: jbaines@lsu.edu EDUCATION 9/75-6/79 Kansas State University, Manhattan, KS. B.S. in Microbiology 9/79-5/83 University of Pennsylvania, Philadelphia, PA, VMD (Veterinary Professional

Degree)

9/83-5/88 Cornell University, Ithaca, NY, PhD in Virology

POSITIONS AND EMPLOYMENT 8/88-8/93 Postdoctoral Fellow in the laboratory of Bernard Roizman, University of Chicago,

Marjorie Oncology Laboratories.

8/93-8/99 Assistant Professor of Virology, Department of Microbiology & Immunology,

Cornell University, College of Veterinary Medicine.

8/99-6/04 Associate Professor of Virology, Department of Microbiology & Immunology,

Cornell University, College of Veterinary Medicine.

6/04-present Professor of Virology, Department of Microbiology & Immunology, Cornell

University, College of Veterinary Medicine.

6/06-9/2014 The James Law Professor of Virology, Department of Microbiology and

Immunology, Cornell University, College of Veterinary Medicine.

9/12-9/2014 Associate Dean for Research and Graduate Education, Cornell University,

College of Veterinary Medicine.

9/14-present Dean, College of Veterinary Medicine, Louisiana State University School of

Veterinary Medicine. PROFESSIONAL MEMBERSHIPS 1983-present Member, American Veterinary Medical Society

1990-present Member, American Society of Microbiology

1991-present Member, American Association for Advancement of Science

J. Baines CV Page 2

1997-present Member, American Society of Virology HONORS

Academic honors: Magna Cum Laude, Kansas State University, 1979.

Phi Kappa Phi honorary Society 1979-present.

Phi Zeta Veterinary Honorary Fraternity, 1994-present.

PROFESSIONAL SERVICE

Cornell nominee, Searle Fellowship, 1995

Pfizer award for excellence in Animal Health Research, 1995.

Session Chair, American Society of Virology meeting, Herpesvirus section, Fort Collins CO,

7/8/00

Session Chair, DNA replication and maturation, International herpesvirus workshop, Cairns

Australia, 2002.

Session Chair, American Society of Virology meeting, Herpesvirus 1 section, College Station,

Pennsylvania July, 2005.

Session Chair, Virus Structure, Maturation and Egress. International Herpesvirus Workshop,

Turku Finland, August, 2005.

Session chair, Virions and egress, and Scientific Advisory Committee, International Herpesvirus

Workshop, Seattle Washington, August, 2006.

Session chair, Gordon Research Conference, Viruses and Cells, Tilton, NH, June 2007.

Session chair, Virions and egress, and Scientific Advisory Committee, International Herpesvirus

Workshop, Asheville, NC, July 2007.

Session Chair, virion assembly and egress, and Scientific Advisory Committee, International

Herpesvirus Workshop, Estoril, Portugal, July 2008.

Organizing committee, American Society of Virology, Cornell University, Ithaca, NY 2008.

Co-organizer, 34th International Herpesvirus Workshop, Cornell University, Ithaca, NY, 2009.

July 25-August 1.

Session Chair, Virus-Host interactions, FASEB Summer Research Conferences, Virus Structure

and Assembly, June 29, 2010.

Member, Faculty of 1000, 2010-present.

Session Chair, Virus assembly and egress 3. International Herpesvirus Workshop, Salt Lake City

Utah, July, 2010.

Session Chair, Virus assembly and egress. International Herpesvirus Workshop, Gdansk,

Poland, August, 2011.

Session Chair, Virus Assembly, International Herpesvirus Workshop, Calgary, Canada, July,

2012.

Session Chair, Virus Assembly and Egress, International Herpesvirus Workshop, Grand Rapids

Michigan July, 2013.

Organizer, Merial symposium for Veterinary Scholars, Cornell University, Ithaca, NY, July

2014.

Session Chair, Virus Assembly, International Herpesvirus Workshop, Boise Idaho, July, 2015.

J. Baines CV Page 3

Reviewer for:

American Journal of Veterinary Research

Antiviral Research

Archives of Virology

Intervirology

Journal of American Veterinary Medical Association

Journal of Clinical Microbiology

Journal of General Virology

Journal of Molecular Biology

Journal of Virology

Journal of Zoological Medicine

MBio

MRC senior fellowships

National Science Foundation

Oncotarget

Plos Pathogens

Plos One

Proceedings of the National Academy of Sciences (USA)

Traffic

USDA Animal Health and Well Being

Virological Methods

Virology

Virology Journal

Viruses

Wellcome trust

Study sections:

Comparative Medicine, NIH, 1996.

Experimental Virology, NIH, 2002-2004

Virology A, NIH, 2005.

Innovation in Virology Study Section, 2005-2008, NIH

Topics in Virology, 2008, 2009

Virology B, NIH, 2007.

P01 panel review, NIH, March 10, 2009

Mail-in Reviewer, Stimulus (RC1) grants. June 2009.

Virology internet review, October 20th, 21st, 2009.

Viology B, February, 2-3, 2010.

Virology B, June 10-11, 2010.

Virology B, Full Member, October, 2010- 2014.

Virology B, Co-Chair, October, 2012-2014.

Special study section: Nuclear organization: the 4D nucleome project. July 2015.

Member Editorial Board for: Journal of Virology

American Journal of Veterinary Research

J. Baines CV Page 4

Virology

Associate Editor:

Plos Pathogens

Co-Editor:

From the Hallowed Halls of Herpesvirology. World Scientific Press, 2012.

University and College Committees/Services

Elected by faculty to the Faculty Council of Representatives 1994-1996 to represent College of

Veterinary Medicine.

Elected to Faculty Senate (1997-1999) to represent Department of Microbiology and

Immunology

Microbiology Seminar Organizational Committee (1994-2000)

Evaluator, Veterinary Students for Veterinary Leadership Training Program, 1998-2004, 2006-

2009, 20011, 2012.

Phi Zeta scientific advisory, evaluated papers for Phi Zeta prize, 1997-present.

Eagle Eye committee, to evaluate and purchase digital work stations for densitometry and photo

documentation for Department Microbiology, Immunology. 1996

Search Committee, 2 Bacteriologists.

Curriculum Design Group, Block IV, host agent and defense (see above; 1996-2012).

Search Committee, new virologist department Microbiology and Immunology, 1995.

University recombinant DNA committee, 1997-2001.

Veterinary Education conference, 1997: lecture on role of large group discussions.

Search Committee, Diagnostic Laboratory Research Specialist, 1998.

Member Curriculum Committee representing department 2002-2006.

Member of General Committee, College of Veterinary Medicine, 2003-2006.

Chair, Curriculum Committee, 2003-2006.

Member, equipment committee for new confocal microscope.

Member, Search committee for chair of department of Comparative Biomedical Sciences, 2006.

Member, reorganization advisory committee Cornell Feline Health Center 7/2006-1/2008

Member ad hoc tenure committee (several)

Member Cornell College of Veterinary Medicine Committee for the Status of Faculty Women

2008-2011.

Member, Committee on Academic Freedom and Professional Status of the Faculty, Cornell

University, 2008-2012.

Member, Deans Council, 2012-present.

Search Committee, Mycobacteriologist, Department of Microbiology and Immunology, Cornell

University.

Advisory committee, Cornell Magnetic resonance Imaging facility, 2012-2014.

Chair’s advisory committee, Department of Microbiology and Immunology. 2009-2014.

J. Baines CV Page 5

PEER REVIEWED PUBLICATIONS

1. Urban,J., Nazaryn, O., Kloppenstein, P. and Baines, J.D. 1981. Genetic studies of a fatty acid

auxotroph of the 15T- strain of Escherichia coli. Canadian Journal of Microbiology

125:1238-1245.

2. Baines, J. D. and B. Roizman. 1991. The open reading frames UL3, UL4, UL10, and UL16 are

dispensable for the growth of herpes simplex virus 1 in cell culture. J. Virol. 65:938-944.

3. Baines, J. D., P. L. Ward, G. Campadelli-Fiume, and B. Roizman. 1991. The UL20 gene of

herpes simplex virus 1 encodes a function necessary for viral egress. J. Virol.

65:6414-6424.

4. Olsen, C. W., W. V. Corapi, C. K. Ngichabe, J. D. Baines, and F. W. Scott. 1992. Monoclonal

antibodies to the spike protein of feline infectious peritonitis virus mediate

antibody-dependent enhancement of infection of feline macrophages. J. Virol.

66:956-965.

5. Baines, J. D. and B. Roizman. 1992. The UL11 gene of herpes simplex virus 1 encodes a

function that facilitates nucleocapsid envelopment and egress from cells. J. Virol.

66:5168-5174.

6. Baines, J. D. and B. Roizman. 1992. The cDNA of UL15, a highly conserved herpes simplex

virus 1 gene, effectively replaces the two exons of the wild type virus. J. Virol.

66:5621-5626.

7. Baines, J. D. and B. Roizman. 1993. The UL10 gene of herpes simplex virus 1 encodes a

novel glycoprotein, gM, which is present in the virion and in the plasma membrane of

infected cells. J. Virol. 67:1441-1452.

8. Baines, J. D., A. H. Koyama, T. Huang, and B. Roizman. 1994. The UL21 gene of herpes

simplex virus 1 is dispensable for replication in cell culture. J. Virol. 68:2929-2936,

1994.

9. Baines, J.D., A. Poon, J. Rovnak, B. Roizman. 1994. The UL15 gene of herpes simplex virus

1 encodes two proteins and is required for cleavage and packaging of viral DNA. J.

Virol. 68:8118-8124.

10. Baines, J. D. and B. Roizman. 1995. The UL11 gene products of herpes simplex virus 1 are

present in nuclear and cytoplasmic membranes, and nuclear dense bodies of infected

cells. J. Virol. 69:825-833.

11. Osterrider, N., Neubauer,A., Brandmuller,C., Braun,B., Kaaden,O., and J.D. Baines. 1996.

The equine herpesvirus type 1 glycoprotein gp21/22a, the herpes simplex virus type 1

gM-homolog, is involved in virus penetration and cell-to-cell spread of virions. J. Virol.

70:4110-4115.

12. Nalwanga,D.K., Rempel, S., Roizman,B., and J.D. Baines. 1996. The UL16 gene product of

herpes simplex virus 1 is a virion protein that colocalizes with intranuclear capsid

proteins. Virology 226:236-242, 1996.

13. Baines, J.D., Cunningham, C., Nalwanga, D.K. and A.J. Davison. 1997. The UL15 Gene of

Herpes Simplex Virus Type 1 Contains Within its Second Exon a Novel Open Reading

Frame that is Translated in Frame with the UL15 Gene Product. J. Virol. 71:2666-2673.

14. Osterrieder, K., A. Neubauer, C. Brandmuller, B. Braun and J.D. Baines. 1997. Synthesis

and processing of the gM protein of equine herpesvirus 1. Virology 232:230-239.

J. Baines CV Page 6

15. Salmon, B. and J. D. Baines. 1998. Herpes simplex virus DNA cleavage and packaging:

association of multiple forms of UL15-encoded proteins with B capsids requires at least

the UL6, UL17 and UL28 genes. J.Virol. 72:3045-3050.

16. Salmon, B., C. Cunningham, A. Davison, and J. D. Baines. 1998. The herpes simplex virus 1

UL17 gene encodes virion tegument proteins that are required for cleavage and packaging

of viral DNA. J. Virol. 72:3779-3788.

17. Rovnak, J., S.L. Quackenbush, J.D. Baines, C.R. Parrish and J. Casey. 1998. Detection of a

novel bovine lymphotropic herpesvirus. J. Virol. 72:4237-4242.

18. Quackenbush S.L, T.M. Work, G.H. Balazs, R.N. Casey, J. Rovnak, A. Chaves, L. duToit,

J.D. Baines, C.R. Parrish, P.R. Bowser and J.W. Casey. 1998. Three closely related

herpesviruses are associated with fibropapillomatosis in marine turtles. Virology

246:392-399.

19. Taus, N.S., B. Salmon and J.D. Baines. 1998. The herpes simplex virus 1 UL17 gene is

required for localization of capsids and major and minor capsid proteins to intranuclear

sites where viral DNA is cleaved and packaged. Virology 252:115-125

20. Taus, N.S. and J.D. Baines. 1998. Herpes simplex virus DNA cleavage and packaging: the

UL28 gene product is a minor component of B capsids. Virology 252:443-449.

21. Salmon, B., D. Nalwanga, Y. Fan and J.D. Baines. 1999. Proteolytic cleavage of the UL15

gene product of herpes simplex virus 1 is coupled with maturation of genomic viral DNA

into unit length genomes. J. Virol. 73:8338-8348.

22. Cunningham, D.A., A.R. Maclean, N.S. Taus and J.D. Baines. 2000. Herpes simplex virus

type 1 UL14: Phenotype of a null mutant and identification of the encoded protein. J.

Virol. 74: 33-41.

23. Reynolds, A.E., Y. Fan and J.D. Baines. 2000. Characterization of the UL33 gene product of

herpes simplex virus 1. Virology 266:310-318.

24. Adelman, K., B. Salmon and J.D. Baines. 2001. Herpes simplex virus DNA packaging

sequences adopt novel structures that are specifically recognized by a component of the

cleavage and packaging machinery. Proc. Nat. Acad. Sci. (USA). vol.98 6:3086-3091.

25. Reynolds, A.E., B. Ryckman, J. D. Baines, Y. Zhou, L. Liang and R.J. Roller. 2001. UL31

and UL34 Proteins of herpes simplex virus type 1 form a complex that accumulates at the

nuclear rim and is required for envelopment of nucleocapsids. J. Virol. 75: 8803-8817.

26. Beard, P.M., N.S. Taus and J.D. Baines. 2002. The DNA cleavage and packaging proteins

encoded by genes UL28, UL15 and UL33 of herpes simplex virus 1 form a complex in

infected cells. J. Virol. 76:4785-4791.

27. Reynolds, A.E., E. Wills, R.J. Roller, B. Ryckman and J.D. Baines. 2002. Ultrastructural

localization of the US3, UL31 and UL34 proteins of herpes simplex virus reveal specific

roles in nucleocapsid envelopment and virion egress. J. Virol. 76: 893-8952.

28. Bjerke, S.L., J.M. Cowan, J.K. Kerr, A.E. Reynolds, J.D. Baines and R.R. Roller. 2003.

Effects of charge cluster mutations on the function of herpes simplex virus type 1 UL34

protein. Virol. 77:7601-10.

29. Beard, P.M., C.L. Duffy, and J.D. Baines. 2004. Quantification of the Cleavage and

Packaging Proteins UL15 and UL28 in Herpes Simplex Virus 1 A and B Capsids. J. Virol.

78:1367-1374.

30. Foster, T.P., J.M Melancon,., J.D Baines, and K.G. Kousoulas. (2004). Herpes simplex

virus type 1 (HSV-1) UL20 modulates membrane fusion events during cytoplasmic virion

morphogenesis and virus-induced cell fusion. 78:5347-5357.

J. Baines CV Page 7

31. Reynolds A. E*., L. Liang*, and J. D. Baines. (2004). Conformational changes of the

nuclear lamina induced by herpes simplex virus 1 require genes UL31 and UL34.

78(11):5564-75. *Contributed equally.

32. Simpson-Holley, M., J. Baines, R. Roller and D. Knipe. (2004). Herpes Simplex Virus 1

UL31 and UL34 Promote the Late Maturation of Viral Replication Compartments to the

Nuclear Periphery. J.Virol. 78 (11):5591-600.

33. Beard, P.M., and J.D. Baines. (2004). The DNA cleavage and packaging protein encoded

by the UL33 gene of Herpes Simplex Virus 1 associates with capsids. Virology

324(2):475-82.

34. Liang, L., M. Tanaka; Y. Kawaguchi, and J.D. Baines. (2004). Cell lines that support

replication of a novel herpes simplex 1 UL31 deletion mutant can properly target UL34

protein to the nuclear rim in the absence of UL31. Virology 329 (1): 68-76.

35. Liang, L., and J.D. Baines (2005). Identification of an essential domain in the Herpes

Simplex Virus 1 UL34 protein that is necessary and sufficient to interact with UL31

protein. J. Virol. 79(6):3797-806.

36. Forest, T, Barnard, S. and J.D. Baines. (2005). Active intranuclear movement of herpes

simplex virus capsids. Nature Cell Biology 7: 429-431.

37. Park, R. and J.D. Baines (2006). Herpes simplex virus type 1 infection induces activation

and recruitment of protein kinase C to the nuclear membrane and increased

phosphorylation of lamin B. J, Virol. 80:494-504. (Featured article)

38. Yang, K and J.D. Baines (2006) The putative terminase subunit of herpes simplex virus 1

encoded by UL28 is necessary and sufficient to mediate interaction between pUL15 and

pUL33. J. Virol 80(12): 5733-5739.

39. Duffy, C., LaVail, J.H., Tauscher, A.N., Wills, E., Blaho, J., and J. D. Baines. (2006)

Characterization of a UL49-null mutant: VP22 of Herpes Simplex Virus 1 Facilitates

Viral Spread in Cultured Cells and the Mouse Cornea. J. Virol. 80(17):8664-8875.

40. Wills, E., Scholtes, L. and J.D. Baines. (2006). The DNA packaging proteins encoded by

UL6, UL15, UL17, UL28, and UL33 of herpes simplex virus 1 are located on the outside

surface of the viral capsid. J. Virol. 80(21): 10894–10899.

41. Jacobson, J.G*, Yang, K*., J.D. Baines, and F.L. Homa. (2006). Linker insertion

mutations in the herpes simplex virus type 1 UL28 gene: Effects on UL28 interaction

with UL15 and UL33 and identification of a second site mutation in the UL15 gene that

suppresses a lethal UL28 mutation. *Contributed equally., J. Virol. 80: 12312-12323.

42. Baines, J.D., Wills, E., Pennington, J., Jacob, R.J., and B. Roizman. (2007). Glycoprotein

M of herpes simplex virus 1 is incorporated into virions during budding at the inner

nuclear membrane. J. Virol. 81:800-812.

43. Baines, J.D., Hsieh, C., Wills, E., Mannella, C., Marko, M. (2007). Electron tomography

of nascent herpes simplex virus 1 virions. . J.Virol. 81 (6): 2726-2735. Epub January 10

[Featured article; cover photograph 81:(12)].

44. Fulmer, P.A. , Melancon, J.A. , Baines, J.D., and Kousoulas, K.G.. (2007). The UL20

protein functions precede and are required for UL11 functions in herpes simplex virus

type-1 (HSV-1) cytoplasmic virion envelopment. J. Virol. 81(7):3097-3108. Epub

January 10. 45. Yang, K., Homa, F., and, J.D. Baines. (2007). Putative terminase subunits of herpes

simplex virus 1 form a complex in the cytoplasm and interact with portal protein in nuclei

of infected cells. J. Virol. 81(12):6419-6433. Epub March 23.

J. Baines CV Page 8

46. Mou, F., Forest, T. and J.D. Baines. (2007). US3 of Herpes Simplex type 1 Encodes a

Promiscuous Protein Kinase that Phosphorylates and Redistributes Lamin A/C in

infected cells. J. Virol. 81(12):6459-6470. Epub. April 16,

47. Leach, N., Bjerke, S.L., Christenson, D., Bouchard, J., Mou, F., Park, R., Baines, J. D.,

Haraguchi, Y., and R.J. Roller. (2007). Emerin is hyperphosphorylated and redistributed

in herpes simplex virus type 1-infected cells in a manner dependent upon both UL34 and

US3. J. Virol. 19:10792-10803 Epub Jul 25..

48.Rasmussen, S.B., Sorensen, L.N., Malmgaard, L., Ank, N., Baines, J.D., Zhijian, J.C.,

Paludan, S.R. (2007). Type 1 IFN production during HSV infection is controlled by cell

type specific viral recognition by TLR9, the MAVS pathway, and novel recognition

systems. J. Virol. 81(24):13315-13324. Epub October 3, 2007.

49.Yang, K., Poon, A.P.W., Roizman, B and J.D. Baines. (2007, 2008). Temperature-sensitive

mutations in the putative herpes simplex virus 1 terminase subunits UL15 and UL33

preclude viral DNA cleavage/packaging and interaction with pUL28 at the nonpermissive

temperature. J. Virol. 82(1):487-494. Epub October 3, 2007.

50. Yang, K., and J.D. Baines. (2008). A domain within herpes simplex virus 1 scaffold

proteins required for interaction with portal protein in infected cells and incorporation of

the portal vertex into capsids. J. Virol. 82(10):5021-30. Epub Mar 12, 2008.

51. Mou, F., E. G. Wills, R. Park, and J. D. Baines (2008). Effects of Lamin A/C, B1 and viral

US3 kinase activity on viral infectivity, virion egress, and targeting the herpes simplex

virus UL34-encoded protein to the inner nuclear membrane J Virol. 2008

Aug;82(16):8094-8104. Epub 2008 Jun 4. 52. Duffy, C, E. F. Mbong, and J.D. Baines. (2008, 2009). VP22 of herpes simplex virus 1

promotes viral protein synthesis late in infection and accumulation of a subset of viral

mRNAs early in infection. J. Virol. 83:1009-1017; E pub, October, 2008.

53. Wisner, T., Wright, C., Kato, A., Mou, F. Baines J.D., Roller R.J. and Johnson, D.C. (2009).

Herpes simplex virus glycoprotein B that promotes fusion at the nuclear envelope is

phosphorylated in a manner dependent on the viral kinase US3 that also promotes nuclear

egress. J. Virol 83:3115-3126.

54. Yang, K. and J.D. Baines (2009). The putative leucine zipper of herpes simplex virus 1

pUL6 is required for interaction with terminase subunits pUL28 and pUL15 and their

incorporation into capsids. J Virol. 83:4557-4564. (Epub, February 2009).

55. Wills, E.G and J.D. Baines (2009). The UL31 and UL34 gene products of herpes simplex

virus 1 are required for optimal localization of viral glycoproteins D and M to the inner

nuclear membrane of infected cells. J. Virol. 83:4800-4809. (Epub, March 11, 2009).

56. Mou, F., EG Wills and J.D. Baines (2009). Phosphorylation of the Herpes simplex virus 1

UL31 protein by the US3 encoded kinase regulates localization of the nuclear

envelopment complex and egress of nucleocapsids. Epub, March 11, 2009. Journal of

Virol. 83:5181-5191.

57. Yang, K. and J.D. Baines. (2009). Proline and tyrosine residues in scaffold proteins of

herpes simplex virus 1 critical to the interaction with portal protein and its incorporation

into capsids. Epub, March 31, 2009. Journal of Virology. 83:8076-8081.

58. Yang, K. and J.D. Baines. (2009). Tryptophan residues in the portal protein of herpes

simplex virus 1 critical to the interaction with scaffold proteins and incorporation into

capsids. Journal of Virology 83 (22):11726–11733.

J. Baines CV Page 9

59. Scholtes, L and J.D. Baines. (2009). Effects of major capsid proteins, capsid assembly, and

DNA cleavage/packaging on the pUL17/pUL25 complex of herpes simplex virus 1.

Journal of Virology. [Editor-Featured article]. Epub October 7, 2009. Journal of

Virology. 83 (24): 12725–12737.

60. Scholtes, L, Yang, K., .Li, L.X., and J.D. Baines (2010). The capsid protein encoded by

UL17 of herpes simplex virus 1 interacts with the tegument protein VP13/14. J. Virol.

2010;84 7642-7650.

61. Roberts, K.L., and J. D. Baines (2010). Myosin Va enhances secretion of herpes simplex

virus 1 virions and cell surface expression of viral glycoproteins. J Virol. 84(19):9889-96.

(Epub June, 2010).

62. Iyer,AS, Morales, JL, Huang, W., Ojo, F., Ning, F. Wills, EG, Baines JD, and A. August..

(2011). Absence of Tec family Kinases Interleukin-2 inducible T cell kinase (Itk) and

Bruton’s Tyrosine Kinase (Btk) severely impairs Fc_RI-dependent Mast Cell Responses.

J. Biol, Chem. 286(11):9503-13. Epub 2011 Jan 6. 63. Roberts, KL and JD Baines. 2011. UL31 of herpes simplex virus 1 is necessary for optimal

NF{kappa}B activation and expression of viral gene products J. Virol.. 85(10):4947-53.

Epub 2011 Mar 9.

64. Yang,K and JD Baines. 2011. Selection of herpes simplex virus capsids for envelopment

involves capsid surface components UL17, UL25 and UL31. Proc. Nat. Acad. Sciences

USA. Aug 23;108(34):14276-81 Epub, August 5, 2011.

65. Yang,K, Wills, EG, and JD Baines. 2011. A Mutation in UL15 of Herpes Simplex Virus 1

That Reduces Packaging of Cleaved Genomes J. Virol.Nov;85(22):11972-80. Epub 2011

Aug 31.

66. Yang, K. E. Wills, and J.D. Baines. 2012. Self cleavage of the herpes simplex virus protease is

required for conformational changes in the portal vertex. Virology 429 (2012) 63–73.

67. Mbong EF, Woodley L, Frost E, Baines JD, and C. Duffy. 2012. Deletion of UL21 causes a

delay in early stages of the herpes simplex virus type 1 replication cycle. J Virol. 2012

Jun;86(12):7003-7. Epub, 4/2012.

68. Le Sage, V, Jung,M., Alter, J., Wills, E., Johnston,S., Kawaguchi, Y., Baines, JD, and Bruce

Banfield. 2013. The Herpes Simplex Virus Type 2 UL21 Protein is Essential for Virus

Propagation". J. Virol 87:5905-5915.

69. S.S Sigamani, H. Zhao, Y. N. Kamau, J. D. Baines and L. Tang. 2013. The structure of the

herpes simplex virus DNA-packaging terminase pUL15 nuclease domain suggests an

evolutionary lineage among eukaryotic and prokaryotic viruses. J. Virol. 87(12):7140-8.

70. Yang, K, . E. Wills and J. D. Baines. 2013. A Herpes Simplex Virus Scaffold Peptide that

binds the Portal Vertex Inhibits Early steps in Viral Replication. J. Virol. 87(12):7140-8.

71. Yang, K., E. Wills, H.Y. Lim, Z. H. Zhou and J.D. Baines. 2014. Association of Herpes

Simplex Virus pUL31 with Capsid Vertices and Components of the Capsid Vertex

Specific Complex. J. Virology. 88:3815-25.

72. Roller, R.J., Haugo, A.C., Yang, K. and J.D. Baines. 2014. The HSV-1 UL51 gene product

has cell type-specific functions in cell-to-cell spread. Journal of Virology. 88:4048-

4058, and Epub, January 14.

73. Zhou, B, Yang, K. and J.D. Baines. 2014. Mutation in the DNA polymerase accessory

factor restores DNA replication of herpes simplex virus 1 in the presence of Raltegravir.

Journal of Virology;88(19):11121-9.

J. Baines CV Page 10

74. Bauer, D, Li, D, Sae-Ueng,, U, Huffman, J, Homa, F, Wilson, K, Leavitt, L, Casjens, S,

Baines, JD., and A. Evilevitch. (2015). Exploring the balance between DNA pressure

and capsid stability in phage and Herpes. Journal of Virology. 89(18):9288-98.

MONOGRAPHS AND INVITED REVIEWS

1. Baines, J.D. 1988. Molecular analysis of Feline Coronaviruses. PhD thesis, Cornell

University.

2. Roizman, B. and J. D. Baines. 1992. The diversity and unity of Herpesviridae. Comp. Immun.

Microbiol. Infect. Dis.

3. Baines, J. D. and B. Roizman. 1993. Application of genetic engineering to study organization

and function of herpes simplex virus genes, p. 283-304. In K. W. Adolph (ed.), Genome

research in molecular medicine and virology. Academic press, Orlando, FA.

4. Baines, J.D. 2001. Cleavage and packaging of herpes simplex virus 1 DNA and envelopment

of nucleocapsids. In Recent Research Developments in Virology.. 3:471-482.

5. Baines, J.D. and S.K. Weller. (2004). Cleavage and packaging of herpes simplex virus 1

DNA. Chapter 9, in Viral Genome Packaging. C. Catalano, Editor. Kluwer

Academic/Plenum Publishers.

6. Baines, J.D. and Duffy, C.D. Chapter 10. (2006) Nucleocapsid assembly and envelopment of

herpes simplex virus. pp. 175-204. In: “Alpha Herpesviruses: Pathogenesis, Molecular

Biology and Infection Control”, edited by Rozeanne Sandri-Goldin, Horizon Scientific

Press.

7. Baines, J.D. and P.E. Pellett. Chapter 5, Genetic Comparison of Human Alphaherpesvirus

genomes. Pp. 65-70. In “The Human Herpesviruses”, Edited by A. Arvin, B. Roizman,

G. Campadelli-Fiume et al. Cambridge University Press, Cambridge, UK. 2006.

8. Baines, J.D.. Chapter 11, Envelopment of herpes simplex virus nucleocapsids at the inner

nuclear membrane pp 143-148. In “The Human Herpesviruses”, Edited by A. Arvin, B.

Roizman, G. Campadelli-Fiume et al. Cambridge University Press, Cambridge, UK.

2006.

9. J.D. Baines and K.L. Roberts. Chapter 11. Nuclear egress and envelopment of HSV.. Nuclear

In: Alphaherpesviruses: Molecular Virology, edited by S. K. Weller. pp. 195-206..

Caister Academic Press. 2010.

10. Roberts, K.L. and J.D. Baines. 2011. Actin in Herpesvirus Infection. Viruses 3, 336-346.

11. Johnson, D. C. and J.D. Baines. 2011. Herpesviruses remodel host membranes for virus

egress. Nature Reviews in Microbiology 9:382-394.

12. Baines, J.D. Herpes Simplex Virus capsid assembly and DNA packaging: a present and

future antiviral drug target. Trends in Microbiology, 19 (2011), pp. 606-613.

13. Baines, J.D. Book Chapter. The Herpes Simplex Virus DNA Packaging Machine. In:

From the Hallowed Halls of Herpesvirology. 2012, World Scientific Press.

PRESENTATIONS

Selected Presentations: Members of my laboratory are regular contributors to the annual international herpesvirus

workshop from 1997-present, and present 1-3 abstracts per meeting. We are also regular

contributors to the American Society of Virology meeting (one abstract every 2 years on average

J. Baines CV Page 11

since 1997), Gordon Conferences on Viruses and Cells (given every 2 years), FASEB meetings

on viral assembly (once every 2 years), and Dynamic Organization of the Nucleus at Cold Spring

Harbor, NY, 2004, 2006. The material in most of these presentations is reflected in the above

publications list.

Selected Invited Presentations:

Mishima Japan at the Eighth International Conference on Immunobiology and Prophylaxis of

Human Herpesvirus Infections. Association of multiple forms of UL15 proteins with

herpes simplex virus capsids requires at least the UL6 and UL28 genes (Brandy Salmon

and Joel Baines). September 1997.

22nd International Herpesvirus Workshop, University of San Diego. The UL17 gene of herpes

simplex virus 1 is required for cleavage and packaging of viral DNA (Brandy Salmon).

August 9, 1997.

25th International Herpesvirus Workshop, Portland, OR. The UL31 gene product is necessary

and sufficient for HSV-mediated reorganization of the nuclear lamina (Dr. Ashley

Reynolds). July 31, 2000.

University of Iowa. DNA packaging of herpes simplex virus 1. June 2001.

University of Virginia, Charlottesville, VA. DNA packaging: focus on the HSV-1 terminase.

April 2002.

State University of Buffalo, Buffalo, NY. Nucleocapsid envelopment of herpesvirions. June

2002.

27th International Herpesvirus Workshop, Cairns Australia. Interaction between the DNA

packaging proteins encoded by UL33, UL15 and UL28 gene products of herpes simplex

virus 1 (Dr. Philippa Beard). July 2002.

The Wadsworth Center, Albany NY. Visualization of nucleocapsid movement and envelopment

in real time. June 2003.

28th International Herpesvirus Workshop, Madison WI, Symposium 2: Virus Maturation and

Egress, Herpesvirus Nucleocapsid Envelopment. July 29, 2003.

11th International Conference on Immunobiology and Prophylaxis of Human Herpesvirus

Infections. Sicily, Italy; 9/10/03. Electron tomographic elucidation of the structure of

recently enveloped herpesvirions.

Phi Zeta Research Emphasis Day, keynote speaker, Louisiana State University, Nucleocapsid

envelopment of herpes simplex virus. September 27, 2003.

Upstate Medical University. 5/27/2004. Invited seminar. Assembly and actin-based transport of

herpesvirus nucleocapsids.

Plenary Speaker. 4th annual herpesvirus symposium, Medical School of the University of

Pennsylvania , 6/09/2004.

University of Illinois at Chicago, February, 2005. Invited seminar. “Herpes simplex virus

nucleocapsid assembly and egress”.

University of Wisconsin at Madison. May 5, 2005. Herpesvirus nucleocapsid intranuclear

movement and egress.” .

12th International Conference on Immunobiology and Prophylaxis of Human Herpesvirus

Infections. Osaka University, Osaka Japan. 10/5/2005. Invited talk. Lamin alterations

mediated by the UL31 and UL34 proteins of herpes simplex virus 1.

Plenary Speaker. October, 2005. Allegheny branch of the American Society for Microbiology.

Herpesvirus nucleocapsid egress, Duquesne University, Pittsburgh, PA.

J. Baines CV Page 12

Mt.. Sinai Medical Center, May 16, 2006, New York, NY. How to get a string in a box: lessons

from herpes simplex virus 1.

Veterinary Virology. Aug. 1, 2006. Cornell University. Summer enrichment program for High

School students.

International Herpesvirus workshop, Seattle, WA. July 2006. Invited oral presentation (Carol

Duffy). Characterization of a VP22 mutant of herpes simplex virus 1.

Humboldt University, Berlin Germany, January 2007. “Herpes simplex virus nucleocapsid

assembly and egress”.

University of Pennsylvania, 7th annual herpesvirus symposium. June 2007. Short talk. Getting

together: assembly of the HSV-1 packaging motor. (Kui Yang).

International herpesvirus workshop. Asheville, NC, July 2007. Invited Oral presentation (Luella

Scholtes). The protein encoded by UL17 of HSV-1 interacts with the major capsid protein

VP5 and a subset of outer tegument proteins.

University of California, Irvine, CA. March 11, 2008. Herpes simplex virus nucleocapsid

assembly and egress.

University of Nevada, Reno. April, 2008. Herpes simplex virus assembly and egress.

University of Pennsylvania, 8th annual herpesvirus symposium. June 2008. Short talk. The

nuclear envelopment complex and nuclear lamins (Fan Mou).

International herpesvirus workshop. July 2008. Estoril, Portugal. Invited Oral presentation.

UL34 interacts with and targets viral glycoproteins to the inner nuclear membranes of

infected cells.

Queens College, March 25th, 2009. Invited seminar. How to manipulate the cell nucleus:

lessons from herpes simplex virus 1.

University of Chicago. May 30th, 2009. Symposium for Bernard Roizman. Invited talk.

Regulation and multiple functions of the HSV-1 nuclear envelopment complex.

Gordon Conference: June 6, 2009. Viruses and Cells. Il Cioccio Italy. Invited talk. Regulation

and multiple functions of the HSV-1 nuclear envelopment complex.

Kobe, Japan. October 3rd, 2009. The little terminase subunit that could: the role of UL33 in viral

replication of herpes simplex virus 1.

State University of NY, Stoneybrook, NY. March 15, 2010. How herpesviruses exit the

nucleus.

University of Pennsylvania, 10th annual herpesvirus symposium. June 2010. Short talk. Myosin

Va’s role in egress of hepes simplex virus virions and glycoproteins. (Kari Roberts).

FASEB Summer Research Conferences, Virus Structure and Assembly, June 29, 2010. The

herpesvirus terminase: an update.

American Society of Virology, Bozeman Montana, July 2010. State of the Art. Egress of herpes

simplex virions.

International Herpesvirus Workshop, Salt Lake City Utah, July 2010, Plenary Talk, Early and

Late Stages in Herpesvirus egress.

Colgate University, February 13th, 2011. Herpesvirus egress from the nucleus.

Texas A and M. March 14, 2011..How herpesviruses exit from the nucleus.

15th Interantional Congress on Immunobiolology and Prophylaxis of human herpesvirus

infections. How nucleocapsids are selected for envelopment at the nuclear membrane.

Venice, Italy, October 13, 2011.

Infectious disease forum, “Contagious Headaches, seizures and Death: Danger in upstate NY”.

December 2, 2011. Cornell University,

J. Baines CV Page 13

Northwestern University, March 22, 2012. How to exploit the nucleus: a lesson from herpes

simplex virus.

Louisiana State University Health at Shreveport. April 4, 2012. Nuclear events in the replication

of herpes simplex virus.

Hershey Medical Center, Hershey, PA, May 3, 2012. Nuclear events in the replication of herpes

simplex virus 1.

Funding opportunities for Veterinarians in the College of Veterinary Medicine, Cornell

University. Cornell University March 12, 2013.

Panel Discussion: The ins and outs of Scientific Publication, February, 2013. Cornell

University.

University of Chicago, Chicago, IL, May, 2013. Nuclear events in the replication of herpes

simplex virus.

Cornell University, June 2013, .Using structure to generate new antiviral compounds: EITA-

New Agriculture Agricultural Science and Technology, Biosystems Engineering.

Grand Rapids Michigan, July, 2013. The structure of a herpesvirus terminase subunit:

implications for new antiviral compounds. DNA maturation section of International

Herpesvirus Workshop.

Washington University at St. Louis, MO. April 4-6, 2014. National Postdoctoral Association.

Summary of successful BEST proposals. Panel discussion.

The role of the veterinarian in Biomedical Research. Stanford University, March 15, 2015.

LSU-HSC,April 8, 2015. New Targets for Antivirals Targeted at Herpesviruses. Dean seminar

series. New Orleans, Louisiana.

September 4, 2015. A Crisper/Cas 9 Screen reveals cellular proteins required for viral infection.

Keynote lecture, The 14th Awaji International Forum on Infection and Immunity.

Awashi, Kobe, Japan.

Pending: R21. “Viral transcription processivity and the UL31 gene product”. Submitted. The long term goal is to determine the role of RNA polymerase II processivity in the regulation of herpesvirus transcription. Ongoing: RO1 AI52341 Baines (PI) Grant Period: 8/01/09 – NCE. Agency: NIH. “Nucleocapsid

envelopment Herpes simplex virus-1” The long-term goal of these studies is to

understand the molecular mechanisms of herpesvirus nucleocapsid envelopment at the

nuclear membrane. $250,000 direct costs per year.

R21 (Baines (PI). Grant Period 1/1/2014-12/31/16. The role of UL33 in HSV DNA packaging. Completed: T32 OD0 11182 Baines (PI). Agency: NIH. Veterinary Student Training in Biomedical

Research. “One year out” program for eterinary experience in research.

T35 OD010941. Baines. PI. Veterinary Investigators program. Agency/ NIH. Summer

Research experience for veterinary students.

DP7 OD018425. Baines. PI. Agency. NIH. “Broadening Experiences in Scientific Training” at

Cornell University. Alternative training experiences are offered to graduate students

J. Baines CV Page 14

throughout Cornell University in Scientific communication, Scientific Policy,

Government Compliance, and Buisness/Entrepeneurship.

RO1 GM50740 Baines (PI) R52 Grant Period: 09/01/08 - 8/31/09. Agency: NIH. “Herpes

Simplex Virus Terminases”. The long-term goal of these studies is to elucidate the

molecular mechanisms by which herpes simplex virus cleaves intranuclear concatameric

viral DNA and packages the DNA into preformed capsids. $250,000 direct costs per year.

RO1 AI52341 Baines (PI) Grant Period: 09/01/08 – 08/28/08. Agency: NIH. “Nucleocapsid

envelopment Herpes simplex virus-1” The long-term goal of these studies is to

understand the molecular mechanisms of herpesvirus nucleocapsid envelopment at the

nuclear membrane. $250,000 direct costs per year.

RO1 GM50740 Baines (PI) Grant Period: 01/03/00 - 12/31/07. Agency: NIH. “Herpes

Simplex Virus Terminases”. The long-term goal of these studies is to elucidate the

molecular mechanisms by which herpes simplex virus cleaves intranuclear concatameric

viral DNA and packages the DNA into preformed capsids. $194,000 direct costs per year.

F32 GM067519 Agency: NIH. “ATP hydrolysis in HSV DNA packaging”. (Carol L. Duffy).

2003-2005. Approximately $80,000 total.

RO1 GM50740-09 Baines (PI) Grant Period: 01/01/00-12/31/03. “Herpes Simplex Virus

Terminases” The long-term goal of these studies is to elucidate the molecular

mechanisms by which herpes simplex virus cleave intranuclear concatameric viral DNA

and packages the DNA into preformed capsids. Approximately $440,000 direct costs. RO1 GM50740-04 Baines (PI) Grant Period: 01/01/95 – 12/31/99. Agency: NIH/NIGMS

“Herpes Simplex Virus Terminases” The specific aims of this project are to identify

roles of UL15 and UL36 gene products in DNA packaging reactions of herpes simplex

virus 1. Approximately $640,000 direct costs. F32 GM20448 National Research Service Award. Ashley Reynolds, DVM. 1999-2002. “The

role of UL33 in DNA packaging of HSV-1”. Approximately $120,000. F32 GM18164 National Research Service Award. Naomi Taus, DVM. 1994-1997. “Role of

UL28 in DNA packaging of HSV-1”. Approximately $108,000.

J. Baines CV Page 15

TEACHING

Veterinary Curriculum

Tutoring: Tutored in Foundation Course IV, Host Agent and Defense for 11 weeks in Fall of

1994, 1996, 1998, and 1999-2001, 2005, 2007, 2009. Per semester, this involves 74

hours (pre 2005) of contact time and after 2005 it involves 40 hours of contact time with

students. Throughout these periods was added approximately 1-2 hours of weekly tutor

meetings. Substitute tutoring in 2003, 2004, 2006, 2008, 2010, 2012, 2013. This consists

of 2-5, 2.5 hour sessions per semester.

Curriculum Design Group: 1996-2012. The curriculum design group designs, revises all

aspects of Foundation Course IV: Host Agent and Defense and writes and grades the two

short answer midterms and essay-based 3-day examinations for approximately 80-90

veterinary students. The committee meets weekly for approximately 1.5 hours during the

course and weekly for 3 months when the course is not in session. This totals

approximately 30 hours per year. I have personally authored sections of the examinations

(1996-2010) and graded those sections and other sections, and authored (1996) and

proctored (1995, 1996) the final oral examination when that format was used.

Laboratories: Block IV Host Agent and Defense: Monitored part of laboratory portion of

course, 1996-2013.

Resource Person for Virology in Professional Curriculum: This involves availability for

student personal learning issues about Virology. This required a 1-2 hours review session

for the entire class (1999, 2000, 2001) and for various tutor groups (for example, 3 such

sessions in 2002, 2 in 2003, 2 in 2004-2007), and availability by email as long as the

course is in session to answer student questions.

Lecturing:

Annually 1994-1997. Foundation Course IV. Host Agent and Defense. 1-hour Lectures were

presented on each of 3 topics: Viral classification, Egress of pathogens from cells, and

Pathogen Self Protection.

1997 and 1999. 24 lectures. VMI 701. Viral Pathogenesis. 2 credits. I was the sole designer and

lecturer in this course. This course was given to 30-40 students which consisted of mostly

veterinary students with 8 graduate students and 2 undergraduates the first year, and a

similar mix with 1 undergraduate the second time it was offered. The course covered a

wide variety of viral diseases of humans and animals to illustrate pathogenetic

mechanisms in a number of organ systems.

Annually 1998-2004.. Foundation Course IV. Host Agent and Defense.1-hour lectures were

presented on each of 2 topics, Viral classification and Viral Replication.

Annually 1997-2005, 2007-2010. Foundation Course IV. Infectious Disease Rounds (Large

group discussion). Pseudodorabies virus. Infectious disease rounds involve a clinician

presenting a theoretical case followed by a scientist to provide underlying information

J. Baines CV Page 16

relevant to the case. This also serves to help wrap up information presented in the

previous week of the course

VMI 739. 1.5 credits. Viruses in Veterinary Medicine. Springs of 2001, 2003, 2005. This was

a traditional lecture-based course that covered the diseases of importance to veterinarians.

The classification, replication, pathogenesis, clinical aspects, control of various

pathogens are covered including agents of potential use as biological terror weapons. I

presented approximately 8 lectures in the course. This was co-taught with Dr. Colin

Parrish and Dr. Klaus Osterrieder. As of Fall of 2005, these lectures and others were

rolled into Foundation Course IV.

Guest Lectures. Guest lectures have been given in various courses including courses given to

undergraduates in basic Virology and viral pathogenesis (approximately 1 per year since

1997), and graduate students in viral replication (1999, 2009).

Annually 1997-2013. Foundation Course IV. Help run laboratory “Intracellular Pathogens”.

Two 3-hour sessions in one week.

Annually 2005-2013. Foundation Course IV lectures in Virology. Approximately 11 lectures on

various veterinary pathogens, viral structure, and viral replication.

Journal Clubs and seminars organized

1994-2001 Organized work in Progress sessions for graduate students to present their data to

the department.

1997-2001 Co-organizer of departmental seminar series in Microbiology, given biweekly.

2001 Co-organizer of Molecular Pathogenesis journal club, given weekly for 1 semester.

Graduate, Undergraduate and Postdoctoral Training

Cornell University Graduate Field Memberships:

Comparative Biomedical Sciences (formerly Veterinary Medicine). 1994-2014.

Microbiology. 2000-2014

LSU Pathobiological Sciences. 2014-2015.

Current and Past Postdoctoral Fellows: Karen Adelman, 1999-2000. Currently: Principle Investigator, National Institutes of

Health.

Carol Duffy, 2001-2007. F32 GM067519. Agency: NIH. ATP hydrolysis in HSV DNA

packaging, 2003-2005. Currently, Associate Professor, University of Alabama.

Philippa Beard, 2000-2003. Currently: Associate Professor, Royal (Dick) School of

Veterinary Studies, Edinburgh, Scotland.

Richard Park 2003-2006, Currently: postdoctoral fellow, Yale University.

Serena Chang 2009-2012. Currently, postdoctoral fellow, Stanford, University.

Kui Yang 2003-2012.

J. Baines CV Page 17

Kui Yang, senior research associate. 2012-2014, Associate, Centers for Disease Control

Atlanta, GA.

Kui Yang, research assistant professor, Louisiana State Univeristy. 2014-present.

Claire Birkenhauer. February 2014-present.

Major Advisor to:

Past:

Dorothy Nalwanga. 1994-1996. Masters degree, Field of Veterinary Medicine. Funded

through Ugandan National Funds. Currently Postodoctoral fellow St. Judes,

Children’s hospital.

Ying Fan. 1995-1997. Masters Degree, Field of Veterinary Medicine, Currently

laboratory technician at National Institutes of Health.

Naomi Taus, DVM. 1995-1999. National Research Service Award, F32 GM18164. Role

of UL28 in DNA packaging of HSV-1. 1994-1997. PhD, Field of Veterinary

Medicine. Currently Veterinary Officer (tenured), University of Washington,

Pullman, WA and, United States Department of Agriculture (joint appointment).

Brandy Salmon. 1997- 2000. PhD. Currently, Associate Director , Office of Licensing

and Ventures, Duke University and Duke University Health Systems

Ashley Reynolds, DVM. 1998-2003. PhD, Field of Veterinary Medicine. National

Research Service Award, F32 GM20448. The role of UL33 in DNA packaging

of HSV-1. 1999-2002. Approximately $120,000. Currently. Researcher and

Lab Animal Medicine, National Institutes of Health.

Li Liang. 1999-2004. PhD. Field of Microbiology. Currently postdoctoral fellow,

University of California, Los Angeles, CA.

Thomas Forest, DVM, Diplomat, American College of Veterinary Pathologists. 2002-

2005. PhD, Field of Comparative Biomedical Sciences. Currently, Scientist,

Pathology, Merck and Company, Inc.

Fan Mou, B.S. 2004-2009. PhD, Field of Comparative Biomedical Sciences. Currently,

Postdoctoral Fellow, Harvard Medical School, Boston, MA.

Luella Scholtes, B.S. Graduated 2003-2009. PhD, Field of Microbiology. Currently, in

Little Rock, Arkansas, head of household.

Kari Roberts, B.S. Graduated July, 2011. Currently, Staff Scientist, Pfizer

Pharmaceuticals, White Plains, NY.

Minor Advisor to: Ni Chen, Veterinary Medicine

Mari Delaney, Veterinary Medicine

Katie Gay, Immunology

Zheng Xing, Veterinary Medicine

Steve Kaplan, Veterinary Medicine

Achim Gruber, Veterinary Medicine

Rebecca Greenblat, Comparative Biomedical Sciences

Myrna Miller, Comparative Biomedical Sciences

J. Baines CV Page 18

Cristina Rosas, Microbiology

Paul Keller, Biochemistry Molecular Biology

Jian Zhou, Entomology

Meagan Wicsnewski Comparative biomedical Sciences

Laura Bramberger Comparative Biomedical Sciences

Robert Ossiboff Comparative Biomedical Sciences

Andrew Regan, Microbiology (exam committee only)

Benedikt Kauffer, Comparative Biomedical Sciences

Ikenna Madu (Biochemistry, Mol. Biol.)

Beth Licitra, (Comparative Biomedical Sciences)

Wisler Charles (Immunology and Infectious Disease)

Undergraduate Students who conducted research in the laboratory (current position if

known): Stephanie Rempel. Hughes Fellowship Summer of 1996.

Mark Noguiera. Spring 1995.

Simon Cheng. Spring and Fall 1996.

Yvette Tenenho, Fall 1997.

Leslie Boxer, Spring 1997.

Pilar Pichon. American Society of Virology minority fellow, Summer 1997.

Garrett Ellsworth. (Physician). Summer 1998.

Leslie Boxer. Fall 1998. (Physician).

Elizabeth Rose. Fall 1998. (currently Dr. of Osteopathy).

Edward_Kazyanskaya. 2000-2001. (Graduate student, Harvard University).

Marisa Isaacson. 2001-2002. (Instructor, Vassar College).

Jane Kaplan. Fall 2002, Spring 2003.

Nicole Cooney, Fall 2003-Spring 2005. (Graduate Student, University of Wisconsin,

Madison).

David Binder, Fall 2005-Fall 2006. (MD/PhD program, University of Chicago).

Lucy X. Li. Spring 2008-Spring 2010, Completed Honors thesis, “Interactions between

HSV tegument proteins.”. (MD/PhD program, Washington University, St. Louis,

MO.)

Nicole Gemmlli/ Fall 2012, Spring 2013.

Veterinary Students trained in conducting research in the laboratory:

Philippa Beard, leadership training program,. Summer 1995.

Ashley Reynolds. Summer 1996.

Joe Wakshlag. 1996.

Rachel Mo. 1997.

Jon Werner. Leadership training program. Summer 1997

Ian Cox. Leadership training program. Summer 1998.

Fiona Norris. Leadership training program. Summer 2000.

Robin Yates. Leadership training program; received program prize. Summer 2001.

Karin Darpel. Leadership training program; received program prize. Summer 2002.

Sandra Barnard. Leadership training program; received program prize. Summer 2003.

J. Baines CV Page 19

Mary Jo Andersen. Leadership training program. Summer 2004.

Andrea McDonald. Leadership training program. received cell biology prize, .Summer

2005,

Lynda Shaw, leadership training program, Summer 2006.

Fiona McNeil, leadership training program, Summer 2007.

Rachel Acciacca, leadership training program, Summer 2008.

Bing Yun Zhu, leadership training program, Summer 2009.

Scott Dudis, veterinary research experience, Summer 2010.

Jakob Trimbert, Veterinary Investigator program, 2011.

Carson Grant, Leadership Program, 2011

Elie Meodownik, Veterinary Investigator Program, 2012

Andrew Durden, Leadership program, 2012

I also served on the committee for student selection and evaluation of summer fellows to join the

leadership training program, 1997-2004, 2006, 2008-2010, 2012, and the Veterinary Investigator

Program 2004, 2006. I was responsible for the veterinary investigator program in 2013 and

2014, and was PI on the grant supporting some of the VIP fellows.

Administrative positions:

Course Leader: Foundation Course IV. Host Agent and Defense.1999-2001. Per semester,

this requires approximately 220 hours of contact time with students, as the course leader

attends tutorials and all lectures, laboratories, and infectious disease rounds during the

course. It also involves chairing the curriculum design group (see aiove), coordinating

scheduling and evaluating faculty teaching efforts, and proctoring the 3 day examination

(8 hours on 2 days, and 4 hours on the final day).

Chair, Curriculum Committee, 2003-2006: The curriculum committee is responsible for

overseeing the entire veterinary curriculum. This involves evaluating the various facets of

the curriculum and proposing solutions to problems in some cases, and evaluating

proposed solutions in others. We have advocated problem based learning in some cases,

and discouraged it in others, depending on the discipline. During my tenure as chair, we

have tried to redefine a core curriculum, and have advocated using this definition to teach

a basic series of courses. These would then be followed by more specific courses for

different species and disciplines. This potentially alleviates the overemphasis of some

portions of clinical medicine at the expense of others, and helps tailor the curriculum to a

wide variety of individual student interests.

Chair, DVM/PhD Oversight committee. 2009-present: This committee oversees post DVM

research training, including a dual degree (DVM/PhD) program, graduate research

associate program (DVMs seeking PhD’s), and a Clinical Fellows Program (Residents

seeking advanced research training). It also involves evaluation and selection of

applicants for post-DVM training in these programs.

J. Baines CV Page 20

Associate Dean for Research and Graduate Education, September 2012-2014. This position

oversees graduate recruitment, graduate education and research conducted by College

faculty. It provides oversight of an Office of Sponsored Programs housed within the

Veterinary College. (The College received over 380 million dollars in research funds

over the last 10 years and our faculty wrote more than 400 papers per annum during that

time.) I was also a co-director of research conducted by the Cornell extension service

which is largely funded by Cornell University and USDA federal formula funds. I

promoted interactions between faculty with common research interests and facilitated

compliance with federal regulations required for safe and responsible conduct of

research. I also helped distribute more than 700,000 dollars per year to help foster clinical

research in food animals, horses and domestic and wild felids by running and overseeing

the competitive grants program that awards these funds. I also helped select veterinary

students and veterinarians for graduate study in the dual degree, and graduate research

fellow programs. In an attempt to reach out to the community and emphasize the One

Health concept, I have helped facilitate interaction between human cancer patients and

our cancer researchers through panel discussions. With considerable help from my staff,

I helped run the Merial Symposium for 400 Veterinary Scholars in 2014, with One

Health as the theme. I served as PI of a Broadening Experiences in Scientific Training

grant awarded by NIH to Cornell University in 2012. This grant encourages and exposes

graduate students and postdoctoral fellows to training in the broad areas of

Entrepreneurship and Business, Public Policy, Regulatory Medicine, and/or Scientific

Communication.

Dean, School of Veterinary Medicine, Louisiana State University, September 2014-Present. The Dean oversees directly or indirectly all aspects of the School of Veterinary Medicine.

Directly reporting to the Dean are the Associate Deans for research and advanced studies,

student and academic affairs, and diversity and faculty affairs, as well as three

departmental chairs representing Clinical Sciences, Comparative Biological Sciences, and

Pathobiology. I initiated the position of Associate Dean for Diversity of Faculty Affairs,

and this has had a remarkable impact on the appreciation of diversity in the School, and

recruitment of faculty and students with diverse backgrounds. The Budget for the School

is approximately 48 million dollars with approximately 110 faculty, 30 interns and

residents in 16 specialties, 50 graduate students, 25 postdoctoral fellows, and 100 staff.

The Dean, in conjunction with the Hospital Director, oversees the Veterinary Teaching

Hospital which has annual revenue of approximately 10 million dollars and sees around

23,000 cases a year, the Louisiana Animal Disease Diagnostic Laboratory that has

revenue of approximately $500,000, and a research enterprise that brings in

approximately 8 million dollars in funding from the National Institutes of Health and

other federal and state agencies. The Dean guides strategic planning for the school’s

missions in teaching, research and service. Immediate goals are to (i) increase research

collaborations of Veterinary faculty with those from other units within LSU and Tulane

University, including both LSU Medical Schools (ii) integrate clinical skills, and an

appreciation for research and discovery throughout the veterinary curriculum. (iii) Raise

10 million dollars for a new Small Animal Wellness Center, which will house Integrative

Medicine, Primary Care, Dentistry, Dermatology, Rehabilitative Medicine, and

Ophthalmology, and (iv) Generate a financially sustainable DVM/PhD program.

J. Baines CV Page 21