Basic Principles of Clinical Immunology.Immune Disorders.Immunodeficiency.

The Main Principles of Immune Correction.

Svitich Oxana Anatolievna

Clinical Immunology.

• Clinical immunology is the study of diseases caused by disorders of the immune system (failure malignant growth of the cellular elements of the system ets.).

• It also involves diseases of other systems, where immune reactions play a part in the pathology and clinical features.

various hypersensitivities

Ets…

Autoimmunity is the system of immune responses of an organism against its own cells and tissues.Autoimmune diseases arise from an abnormal immune response of the body against substances and tissues normally present in the body (autoimmunity). This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney).

Gen

Hormone

Suppression of T-cells environmental factors

proliferation of В-cells

Гиперактивность плазматических

клеток

Ab rise

Against tissue against the nucleus of the cell

Ag-Ab in tissues

hyperactivation of the immune system Symptom - death

Oncology in the immune systemLymphoid leukemias (also called lymphocytic, lymphogenous, or lymphoblastic leukemias) are a group of leukemias affecting circulating lymphocytes, a type of white blood cells.

Such diseases are all lymphoproliferative disorders. Most lymphoid leukemias involve a particular subtype of lymphocytes, the B cells.

immunodeficiency• Primary immunodeficiency

• secondary immunodeficiency

Primary immunodeficiency disorders: examples and typical presentation

Primary immunodeficiencies are disorders in which part of the body's immune system is missing or does not function normally. To be considered a primary immunodeficiency, the cause of the immune deficiency must not be secondary in nature (i.e., caused by other disease, drug treatment, or environmental exposure to toxins). Most primary immunodeficiencies are genetic disorders; the majority are diagnosed in children under the age of one, although milder forms may not be recognized until adulthood. About 1 in 500 people are born with a primary immunodeficiency.

• The Main Principles of Immune Correction.

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