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By Prof.Dr. Syafruddin Ilyas, M.Biomed
Biology Department of Faculty of Mathematics
and Natural Sciences, Univ. of North Sumatra
Introduction of The Lecture
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Main Topics1. Animal Tissue
2. Integument System
3. Sirculation System
4. Digestive System
5. Respiration System6. Endocrine System
iology Department of Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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Lecture Materials
Power Point for Main Lectures Lecture Note
Video
Animation Movie
iology Department of Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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Evaluation
10% = Quiz 15% = homework
25% = Mid Term examination
50% = Final Term examination (EM)
iology Departmentof Faculty of Mathematics and Natural Sciences,
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By ; Prof.Dr. Syafruddin Ilyas, M.Biomed.(1) Animal Tissues
iology Departmentof Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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Animal Tissues The development of a fertilized egg into a newborn
child requires an average of 41 rounds of mitosis
(241 = 2.2 x 1012).
During this period, the cells produced by mitosisenter different pathways of differentiation; some
becoming
blood cells,
some muscle cells, and so on.
iology Departmentof Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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ANIMAL TISSUES
http://users.rcn.com/jkimball.ma.ultranet/BiologyPa
ges/A/AnimalTissues.html
iology Departmentof Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
Drawings1. Epithelial
2. Muscle
3. Connective
Supporting connective
tissue Dense connective tissue
Loose connective tissue
Adipose tissue4. Nerve
Neurons
Glia5. Blood
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AnimalTissue
1.Epithelial
2. Muscle
3.Connective
4. Nerve
5. Blood
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There are more than 100 visibly-distinguishablekinds of differentiated cells in the vertebrate
animal.
These are organized into tissues; the tissues
into organs.
Groups of organs make up the various systems
digestive,
excretory, etc. - of the body.
iology Departmentof Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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The actual number of differentiated cell types
is surely much larger than 100.
All lymphocytes, for example, look alike but
actually represent a variety of different
functional types, e.g., B cells, T cells ofvarious subsets.
The neurons of the central nervous system
must exist in a thousand or more differentfunctional types, each representing the result
of a particular pathway of differentiation.
iology Department of Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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1. Epithelial Epithelial tissue is made of closely-packed cells arranged in flat
sheets. Epithelia form the surface of the skin, line the various cavities
and tubes of the body, and cover the internal organs.
Subsets of Epithelia
Epithelia that form the interface between the internal and
external environments.
Skin as well as the lining of the mouth and nasal cavity.
These are derived from ectoderm. Inner lining of the GI tract, lungs, urinary bladder, exocrine
glands, vagina and more. These are derived from
endoderm.
iology Department of Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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Each of these will have special roles to play in building thecomplete animal.
Some are listed in the table.
Germ-layer origin of various body tissues
Ectoderm Mesoderm Endoderm
skin notochordinner lining of gut, liver,
pancreas
brain muscles inner lining of lungs
spinal cord blood inner lining of bladderall other
neuronsbone
thyroid and parathyroid
glands
sensereceptors
sex organs thymus
iology Departmentof Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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The apical surface of these epithelial cells isexposed to the "external environment", the
lumen of the organ or the air. [View example]
Mesothelia. These are derived from mesoderm. pleura the outer covering of the lungs and
the inner lining of the thoracic (chest) cavity.
peritoneum the outer covering of all theabdominal organs and the inner lining of the
abdominal cavity.
pericardium the outer lining of the heart.
iology Department of Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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Endothelia. The inner lining of the heart, all
blood and lymphatic vessels derived from
mesoderm.
The basolateral surface of all epithelia is
exposed to the internal environment (ECF).
The entire sheet of epithelial cells is attached
to a layer of extracellular matrix that is called
the basement membrane or, better (because itis not a membrane in the biological sense),
the basal lamina. [View example]
iology Department of Faculty of Mathematics and Natural Sciences,
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View showing relationship between the apical
and basolateral surfaces of epithelial cells and
how they maintain their distinction. The
function of epithelia always reflects the fact
that they are boundaries between masses of
cells and a cavity or space. Some examples:
iology Department of Faculty of Mathematics and Natural Sciences,
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The epithelium of the skin protects the
underlying tissues from
mechanical damage
ultraviolet light
dehydration
invasion by bacteria
iology Departmentof Faculty of Mathematics and Natural Sciences,
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The columnar epithelium of the intestine secretes digestive enzymes into the
intestine; absorbs the products of digestion from it.
An epithelium also lines our air passages and
the alveoli of the lungs. It secretes mucuswhich keeps it from drying out and trapsinhaled dust particles. Most of its cells have
cilia on their apical surface that propel themucus with its load of foreign matter back upto the throat.
iology Departmentof Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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2 Muscle
Three kinds of muscle are found in
vertebrates: Skeletal muscle is made of long
fibers whose contraction provides the force of
locomotion and other voluntary body
movements.
Smooth muscle lines the walls of the hollow
structures of the body, such as the intestine,
urinary bladder, uterus, and blood vessels. Itscontraction, which is involuntary, reduces the
size of these hollow organs.
iology Department of Faculty of Mathematics and Natural Sciences,
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The heart is made of cardiac muscle.
Link to page devoted to the structure and
properties of the three kinds of muscles.
iology Departmentof Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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3 Connective
The cells of connective tissue are embedded in a great amount
of extracellular material.
This matrix is secreted by the cells.
It consists of protein fibers embedded in an amorphous mixture
of protein-polysaccharide ("proteoglycan") molecules.
Supporting connective tissue
Gives strength, support, and protection to the soft parts of thebody.
Cartilage.
Example: the outer ear Bone.
The matrix of bone contains collagen fibers and mineral
deposits. The most abundant mineral is calcium phosphate,
although magnesium, carbonate, and fluoride ions are also
present. [More on bone]
iology Department of Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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Dense connective tissue
Often called fibrous connective tissue. Tendons connect
muscle to bone. [View] The matrix is principally Type I
collagen, and the fibers are all oriented parallel to each other.
Tendons are strong but not elastic.
Ligaments attach one bone to another. They contain both
collagen and also the protein elastin. Elastin permits ligaments
to be stretched.
Loose connective tissue
It is distributed throughout the body. It serves as a packing and
binding material for most of our organs. Collagen, elastin, andother proteins are found in the matrix.
Both dense and loose connective tissue is derived from cells
called fibroblasts [View], which secrete the extracellularmatrix.
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Adipose tissue
Adipose tissue is "fat". There are two kinds
found in mammals: white adipose tissue
(WAT) in which the cells, called adipocytes,
have become almost filled with oil.
The oil is confined within a single membrane-bound droplet.
Virtually all of the "fat" in adult humans is
white adipose tissue.
iology Department of Faculty of Mathematics and Natural Sciences,
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brown adipose tissue (BAT) in which the adipocytes
contain many small droplets of oil as well as many
mitochondria. White adipose tissue and brown adipose tissue differ
in function as well as cellular structure.
These differences are described on a separate page.
Link to it
New adipocytes in white fat are formed throughout lifefrom a pool of precursor cells. These are needed to
replace those that die (after a life span of about 100
days).
iology Department of Faculty of Mathematics and Natural Sciences,
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Whether the total numberof these adipocytes
increases in humans becoming fatter as
adults is still uncertain.
If not, why do so many of us get fatter as we
age? Because of the increased size ofindividual adipocytes as they become filled
with oil.
The adipocytes of white fat secrete severalhormones, including leptin and adiponectin.
iology Departmentof Faculty of Mathematics and Natural Sciences,
University of North Sumatra Medan INDONESI
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4 Nerve
Nerve tissue is composed of nerve cells called
neurons and
glial cells.
Neurons
Neurons are specialized for the conduction of nerveimpulses. A typical neuron consists of a cell body
which contains the nucleus;
a number of short fibers dendrites extending
from the cell body
a single long fiber, the axon. The nerve impulse is conducted along the axon.
iology Department of Faculty of Mathematics and Natural Sciences,
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Glia
Glial cells surround
neurons.
Once thought to be
simply support forneurons (glia =
glue), they turn out
to serve severalimportant functions.
iology Department of Faculty of Mathematics and Natural Sciences,
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5 Blood
The bone marrow is the source of all the cells of
the blood. These include: red blood cells (RBCs orerythrocytes)
five kinds ofwhite blood cells
(WBCs or
leukocytes)
platelets (or thrombocytes)
Link here to a page describing the blood cells indetail. Welcome&Next Search
iology Departmentof Faculty of Mathematics and Natural Sciences,
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