· 2018-05-09 · Table of Contents List of Figures...

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology Implementation Roadmap on value chains and related pilot lines

Transcript of  · 2018-05-09 · Table of Contents List of Figures...

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology

Implementation Roadmap on value chains and related pilot lines

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Produced by: Value4Nano: Industrial valorisation of strategic value chains for nano-enabled products (Grant agreement no. 608684) Project coordinator: D’Appolonia, S.p.A.

Project partners: NANOfutures asbl Fundación PRODINTEC

D.L.: AS 001982-2015

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology

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Table of Contents

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Table of Contents

List of Figures ................................................................................................ VIIList of Tables ............................................................................................... VIIIList of Acronyms and Abbreviations ......................................................................... XIPrefix ............................................................................................... XIIIExecutiveSummary ................................................................................................XV1 Introduction ...................................................................................................12 Methodology ...................................................................................................7 2.1 Background – The NANOfutures Experience ...............................................................7 2.2 Outcome of the Roadmapping Activity ..........................................................................9 2.3 Roadmapping Steps ....................................................................................................12 2.3.1 Gap Analysis Methodology ...............................................................................13 2.3.2 Methodology for completion of the actions .......................................................13 2.3.3 Methodology for pilot lines feasibility assessment (including business modelling and planning) ....................................................14

3 Value Chains Roadmaps .......................................................................................17 3.1 VC1 - Nano and micro printing for industrial manufacturing Roadmap .......................19 3.1.1 VC1 Impact .......................................................................................................22 3.2 VC2 - Nano-enabled, depollutant and self-cleaning surfaces Roadmap ....................23 3.2.1 VC2 Impact .......................................................................................................26 3.3 VC3 - Manufacturing of powders made of functional alloys, ceramics and intermetallics Roadmap ........................................................................27 3.3.1 VC3 Impact .......................................................................................................29 3.4 VC4 - Lightweight multifunctional materials and composites for transportation Roadmap ........................................................................................30 3.4.1 VC4 Impact .......................................................................................................33

4 Cross-cutting non-technical actions ....................................................................37 4.1 Non-technical actions Impact ......................................................................................40

5 Pilot Lines roadmaps .............................................................................................43 5.1 Pilot Line 1 – Nanostructured surfaces and nanocoatings ..........................................45 5.1.1 Pilot Line 1a - Nanostructured antimicrobial, antiviral surfaces for medical devices, hospitals, etc ........................................45 5.1.2 Pilot Line 1b - Nanocoatings for mechanically enhanced surfaces ..................49 5.2 Pilot Line 2 – Manufacturing of lightweight multifunctional materials with nano-enabled customised thermal/electrical conductivity properties ...................53 5.3 PilotLine3–PrintedmicrofluidicMEMSandbiologicalapplications .........................59 5.3.1 PilotLine3a-Nozzles,filters,sensorapplicationsandmulti-usechip ............59 5.3.2 Pilotline3b-PrintedmicrofluidicMEMSandbiologicalapplications: Bio-medical/bio-physicals sensors, actuators and other devices .....................63

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5.4 Pilot Line 4 – Non mainstream Micro-Electro-Mechanical Systems and Architectures ........................................................................................................66 5.4.1 Pilot Line 4a - Non mainstream Micro-Electro-Mechanical Systems and Architectures: Advanced CMOS compatible digital fabrication ..................66 5.4.2 Pilot Line 4b - Non mainstream Micro-Electro-Mechanical Systems and Architectures:CheapflexiblehybridorfullpolymerMEMSecosystems..........70 5.5 Pilot line risk analysis ......................................................................................................74 5.5.1 Introduction .......................................................................................................74 5.5.2 Pilot line 1 risk analysis ....................................................................................76 5.5.3 Pilot line 2 risk analysis ....................................................................................77 5.5.4 Pilot line 3 risk analysis ....................................................................................78 5.5.5 Pilot line 4 risk analysis ....................................................................................79

6 AppendixI-VC1-Nanoandmicroprintingforindustrial manufacturing Actions Description Fiches .........................................................83

7 AppendixII-VC2-Nano-enabled,depollutantandself-cleaning surfaces Actions Description Fiches .................................................................105

8 AppendixIII-VC3-Manufacturingofpowdersmadeoffunctionalalloys,ceramics and intermetallics Actions Description Fiches ................................119

9 AppendixIV-VC4-Lightweightmultifunctionalmaterials and composites for transportation Actions Description Fiches .....................131

10AppendixVNon-technicalActionsDescriptionFiches ...................................147

11 AppendixVI-PilotLine1Nanostructuredsurfaces and nanocoatings Description ...........................................................................181

12AppendixVII-PilotLine2Manufacturingoflightweightmultifunctional materialswithnano-enabledcustomisedthermal/electricalconductivityproperties Description .........................................................................................185

13AppendixVIII-PilotLine3PrintedmicrofluidicMEMS and biological applications Description ............................................................189

14AppendixIX-PilotLine4NonmainstreamMicro-Electro-Mechanical SystemsandArchitecturesDescription ............................................................195

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Figure 1-1: A European “three-pillar bridge” to pass across the “valley of death” ...................1Figure 1-2: EfficiencyandfragmentationofpublicSupportinEurope. ...................................2Figure 1-3: NANOfutures linked ETPs ....................................................................................3Figure 1-4: Examples of products ...........................................................................................4Figure 2-1: Overview of NANOfutures value chains and related target markets .....................7Figure 2-2: Structure of NANOfutures Value chain based roadmaps ......................................8Figure 2-3: Value Chain scheme .............................................................................................9Figure 2-4: Steps of the Value Chain (economic layer) .........................................................10Figure 2-5: Steps of the Production Chain (technical layer) ..................................................10Figure 2-6: Steps of the Societal Chain .................................................................................11Figure 2-7: Scheme of roadmapping Process .......................................................................12Figure 2-8: Pilot Line Characterization Process ....................................................................14Figure 3-1: Roadmap Template .............................................................................................18Figure 3-2: VC1 Roadmap summary .....................................................................................19Figure 3-3: VC1 Products clustering .....................................................................................20Figure 3-4: VC2 Roadmap summary .....................................................................................23Figure 3-5: VC2 Products clustering .....................................................................................24Figure 3-6: VC3 Roadmap summary .....................................................................................27Figure 3-7: VC4 Roadmap summary .....................................................................................30Figure 3-8: VC4 Products clustering .....................................................................................31Figure 4-1: Non-technical actions roadmap summary ...........................................................37Figure 4-2: From Societal Challenges to products towards proposed actions ......................40Figure 4-3: Exampleofpathtowardaddressing“CleanandefficientEnergy”,

“Greentransport”and“Climateaction,resourceefficiencyandrawmaterials”Societal Challenges ............................................................................................41

Figure 5-1: Pilot Lines Roadmap summary ...........................................................................44Figure 5-2: Example of Risk Matrix (exposure vs hazard) ....................................................75

List of Figures

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List of Tables

Table 0-1: List of Pilot Lines and related Value Chains ......................................................XVITable 1-1: Market-driven Value Chains ..................................................................................4Table 2-1: List of Pilot Lines .................................................................................................15Table 3-1: VC1 Actions Summary ........................................................................................21Table 3-2: VC1 Expected Impact .........................................................................................22Table 3-3: VC2 Actions Summary ........................................................................................25Table 3-4: VC2 Expected Impact .........................................................................................26Table 3-5: VC3 Actions Summary ........................................................................................28Table 3-6: VC3 Expected Impact .........................................................................................29Table 3-7: VC4 Actions Summary ........................................................................................32Table 3-8: VC4 Expected Impact .........................................................................................33Table 4-1: Non-Technical Actions Summary ........................................................................38Table 5-1: Pilot Line 1a Actions Summary ...........................................................................45Table 5-2: Pilot Line 1a Business Plan ................................................................................47Table 5-3: Pilot Line 1a - Examples of possible Consortia Structures .................................48Table 5-4: Pilot Line 1b Actions Summary ...........................................................................49Table 5-5: Pilot Line 1b Business Plan ................................................................................51Table 5-6: Pilot Line 1b - Examples of possible Consortia Structures .................................52Table 5-7: Pilot Line 2 Actions summary ..............................................................................53Table 5-8: Pilot Line 2 Business Plan ..................................................................................55Table 5-9: Pilot Line 2 - Examples of possible Consortia Structures ...................................56Table 5-10: Pilot Line 3a Actions Summary ...........................................................................59Table 5-11: Pilot Line 3a Business Plan ................................................................................61Table 5-12: Pilot Line 3a - Examples of possible Consortia Structures .................................62Table 5-13: Pilot Line 3b Actions Summary ...........................................................................63Table 5-14: Pilot Line 3b Business Plan ................................................................................65Table 5-15: Pilot Line 3b - Examples of possible Consortia Structures .................................65Table 5-16: Pilot Line 4a Actions Summary ...........................................................................66Table 5-17: Pilot Line 4a Business Plan ................................................................................68Table 5-18: Pilot Line 4a - Examples of possible Consortia Structures .................................69Table 5-19: Pilot Line 4b Actions Summary ...........................................................................70Table 5-20: Pilot Line 4b Business Plan ................................................................................72Table 5-21: Pilot Line 4b - Examples of possible Consortia Structure ...................................73Table 5-22: Overview of the potential risks of nanomaterials ................................................74

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List of Acronyms and Abbreviations

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Implementation Roadmap on value chains and related pilot lines XI

List of Acronyms and Abbreviations

AFM Atomic Force MicroscopyBAT Best Available TechnologiesCEOs ChiefExecutiveOfficersCMOS Complementary Metal-Oxide SemiconductorCRMs Critical Raw MaterialsCSA Coordination and Support ActionERA European Research AreaETPs European Technology PlatformsHLG High Level GroupHVOF High Velocity Oxy FuelIA Innovation ActionKETs Key Enabling TechnologiesLCA Life Cycle AnalysisLCC Life Cycle Cost AnalysisMEMS Micro-Electro-Mechanical SystemsNA Not AvailableOECD Organisation for Economic Co-operation and DevelopmentOLED Organic Light Emitting DiodeOPV Organic PhotoVoltaic materialOTFT Organic Thin Film TransistorRIA Research and Innovation ActionRRI Responsible Research and InnovationRTOs Technological Research OrganisationsR&D Research and DevelopmentSMEs Small and Medium EnterprisesTCO Transparent Conductive OxideTRL Technology Readiness LevelVC Value ChainWG Working Group

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Prefix

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Implementation Roadmap on value chains and related pilot lines XIII

Prefix

This document aims at presenting the NANOfutures Implementation Roadmap on value chains and related pilot lines (2015-2022).

This Roadmap constitutes an openworkingdocument, developed in the framework of the VALUE4NANO project “Value4Nano: Industrial valorisation of strategic value chains for nano-enabled products” (Grant Agreement No:608684).

This document has been developed with all NANOfutures Platform members and other stakehold-ers from the Nano related Community who wanted to contribute.

Version: August 2015.

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Executive Summary

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Implementation Roadmap on value chains and related pilot lines XV

The Value4Nano project has as its central aim the valorisation and elaboration of four key European value chains, which utilise nanomaterials.

The Value Chains are:

• VC1 - Nano and micro printing for industrial manufacturing • VC2 - Nano-enabled, depollutant and self-cleaning surfaces • VC3 - Manufacturing of powders made of functional alloys, ceramics and intermetallics • VC4 - Lightweight multifunctional materials and composites for transportation

This document is the Implementation Roadmap for the valorisation of nano-enabled technolo-gies, services and products. The roadmap was successfully performed with an inclusive approach, involving project partners, Value Chain expert groups and NANOfutures large Working Groups, by means of surveys and face-to-face meetings.

The roadmap includes an overall plan focusing on short, medium term actions proposed for the period 2015-2022, as well as detailed roadmaps for each Value Chain. Cross-cutting non-technical actions are also included. Description of the impact is provided for each short, medium term action, togetherwithotherdetails(specificchallenges,scopeoftheaction,startingandexpectedTRL,needed resources etc.). Long term actions (beyond 2022) are then drafted.

Among the proposed short, medium term actions there are pilot line actions, which were ana-lysed in detail by the expert groups, providing extended feasibility studies (quantitative impact and targets, business modelling, guidelines for business plans and risk analysis).

Executive Summary

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The following pilot lines were selected (they are listed in order of priority as given by the experts):

Table 0-1: List of Pilot Lines and related Value Chains

Pilot Line ID Title of the Pilot Line Value Chain

Pilot Line 1

Nanostructuredsurfacesandnanocoatings, divided into:• Pilot1a:Nanostructuredantimicrobial,antiviralsurfacesformedical

devices, hospitals, etc.• Pilot1b:Nanocoatingsformechanicallyenhancedsurfaces

VC2

Pilot Line 2 Manufacturingoflightweightmultifunctionalmaterialswithnano-enabledcustomisedthermal/electricalconductivityproperties VC4

Pilot Line 3

PrintedmicrofluidicMEMSandbiologicalapplicationsdivided into:• Pilot3a:Nozzles,filters,sensorapplicationsandmulti-usechip• Pilot3b:Bio-medical/bio-physicalssensors,actuatorsandother

devices

VC1

Pilot Line 4

NonmainstreamMicro-Electro-MechanicalSystemsandArchitectures” related to:

• Pilot4a:AdvancedCMOScompatibledigitalfabrication• Pilot4b:CheapflexiblehybridorfullpolymerMEMSecosystems

VC1

The roadmap was:

• Discussed and endorsed by key industries of the value chains in the Industry Alliance Meet-ing (Brussels, 7th May 2015);

• Submitted for open consultation on the NANOfutures Platform website, during May - July 2015, in order to collect feedbacks from inside (more than 1,000 registered members) and outside Nano-technology communities;

• Discussed during the Value4Nano/NANOfutures workshop at EuroNanoForum 2015 (Riga, 12thJune2015)andfinallyvalidatedbytheNANOfutures Steering Committee (ETPs and WG chairs meeting in Riga on the same date).

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1 Introduction

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Implementation Roadmap on value chains and related pilot lines 1

During the second decade of the 21st century, Europe has been facing a series of crucial chal-lenges:lowgrowth,insufficientinnovation,andadiversesetofenvironmentalandsocialchal-lenges. Europe 2020, the EU’s comprehensive long-term strategy, recognises these challenges and argues that Europe is experiencing a moment of transformation.

Whilstasignificantpartofthegoodsandservicesthatwillbeavailableinthemarketsofthe2020’s are yet unknown, the main driving force behind their development will be the deployment of KETs1.RecognisingtheurgencyofstrengtheningEuropeanindustryinthefieldofKETs,thecommissioners Vice president Tajani, Geoghean-Quinn and Kroes mandated a High Level Group (HLG), bringing together CEOs of major industries and major Technological Research Organiza-tions(RTO’s)activeinthefieldofKETswiththemissiontoidentifythecausesofthisgapandpropose corrective measures.

An important conclusion of the HLGisreflectedinthenowfa-mous picture of the bridge and thethreepillars,identifyingthe ‘valley of death’ that sepa-rates basic concepts (science) from commercial products (market). The process to fill this gap relies on three phases of development: technological research, product development and competitive manufacturing. Interrupted, the process does not result in expected return on investment in terms of growth and jobs leading to low effec-tiveness of research invest-ment.

To boost future productivity and growth, it is critically important to generate breakthrough tech-nologies and to translate them into innovations (new products, processes and services) that are taken up by the wider economy. However, while Europe has taken an early technological lead in many green and ‘quality of life’ (health, security, etc.) technologies, its advantage is tenuous in the face of growing competition, and has not been translated into an innovative and competitive lead.

1 Introduction

1 Basedoncurrentglobalresearchandmarkettrends,theCommissionhasidentified6strategicKETsfortheEU:(1)micro-/nano-electronics, (2) nanotechnology, (3) photonics, (4) advanced materials, (5) industrial biotechnology, and (6) advanced manufacturing technologies.

2 High-Level Expert Group Final Report on Key Enabling Technologies (June 2011).

Figure 1-1: A European “three-pillar bridge” to pass across the “valley of death”2

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology2

The case of nanotechnology is an illustration of a sector in which Europe has not a leading innova-tion performance. This is caused by the negative impact that fragmentation of public resources has on nanotechnology innovation performance. According to several recent estimates3, the Union spends around €1.5 billion annually in nanotechnology research (including the 27 Member States’ national funding and EC funding), which is considerably more than the USA (€1 billion), Japan (€0.47 billion) and China (€0.1 billion). However, as highlighted in a recent Communication of the EC4, despite these relatively high levels of funding, the EU is not as successful in deploying nanotechnol-ogy as for example the US, when looking at the ability to transfer knowledge generated through R&D intopatents.Figure1-2showsthescientificandtechnologicalperformanceofselecteddevelopedand emerging countries (expressed in terms of the number of patents per 1M€ of public R&D support (2000-2005) and the number of highly cited publications per 1M€ public R&D, with the size of the bubble representing the volume of public R&D funding). Fragmented public funding in Europe leadstolowerscientificandtechnologicaloutputspereuroinvested:theefficiencyofEUcountriescan be seen lagging behind the US and the OECD average. Given the relatively low numbers in-volved, the performances of those countries with low funding levels should not be over-interpreted.

Figure1-2:EfficiencyandfragmentationofpublicSupportinEurope.Source: DG Research and innovation. Data: Larsen et al (2011);

Roco et al (2010), OECD (2008, 2009).

In order to advance ERA and Innovation Union objectives and reduce fragmentation, it is vital to implementnano-promisingrelatedresearchintoactivitiesandfinallyintokeymarketableproducts.

The NANOfuturesinitiative, the Integrating Technology and Innovation Platform on nanotech-nology launched in 2009 by NANOfutures association, hastheskillsandnetwork(drivenbyindustries) to lead this process. NANOfutures links together more than 1,000 nano-related stakeholders5: industries, research centres and universities, public organisations, national and regional clusters, standardisation bodies, banks, investors and developers. The wide participation of European experts and stakeholders is guaranteed by an online web platform (www.nanofutures.eu) as well as by the recent networking and strategic activities performed in NANOfutures working groups during workshops and dissemination meetings.

3 Estimations included in “Impact assessment accompanying the Communication from the Commission ‘Horizon 2020 – The Framework Programme for Research and Innovation’ ”, 30 November 2011 and derived from NMP Scoreboard, 2011; Roco et al., 2010; OECD 2009;

4 SEC(2009) 1257.5 Figures updated in August 2015. The experts involved in the different NANOfutures working groups are listed in the

website and visible upon free registration (www.nanofutures.eu).

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Implementation Roadmap on value chains and related pilot lines 3

In fact NANOfutures involves 10 Working Groups (WGs), large groups of voluntary experts cover-ing broad technological and non-technological issues such as safety, standardization, technology transferandinnovationfinancing,education,regulation,researchandtechnology,industrialisation,networking, communication and CRMs.

Moreover, NANOfutures has created a network of national/localandinternationalrepresenta-tives (“Lighthouses”) able to translate and inform on key local nanoactivities and relevant projects and practices.

NANOfutures is guided by a Steering Committee, formed by the Chairs of Horizontal Working Groups and 11 industrial European Technology Platforms (ETPs) from different industry sectors:

• Textiles ETP: ETP for the Future of Textile and Clothing; • NANOMEDICINE ETP; • SusChem: ETP on Sustainable chemistry • ECTP: European Construction Technology Platform; • ENIAC: Nanoelectronics platforms; • MANUFUTURE: ETP on Advanced manufacturing; • MINAM: ETP on micro and nanomanufacturing; • ERTRAC: ETP Transportation; • EUMAT: ETP on Advanced Engineering Materials and Technologies; • PHOTONICS21: European Technology Platform for photonics; • ETPIS: ETP on Industrial Safety.

Figure 1-3: NANOfutureslinkedETPs

The NANOfutures Research and Industrial Roadmap developed in the framework of the past NANOfutures CSA6definedindustry-driven-valuechainsinvolvingmanyindustrialandresearchexperts and other stakeholders.

ThepresentImplementationRoadmapfocusesonaspecificsetofNANOfutures market-driven value chains aimed at particular applications (presented in detail in Table 1-1), bringing forward a clear plan for their implementation in order to develop successfully and socially sustainable products, including detailed business modelling and planning for a set of pilot lines and involving strategic industries and other stakeholders.

6 Grant Agreement No. NMP4-CA-2010-266789. Project duration: October 2010- September 2012.

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Table1-1:Market-drivenValueChains

Market-drivenValueChains ExamplesofTargetProducts

VC1 Nano and micro printing for industrial manufacturing Sensors & medical devices

VC2Nano-enabled,depollutantandself-cleaning surfaces

Paints and coatings for buildings & medical devices

VC3Manufacturingofpowdersmadeoffunctionalalloys,ceramicsandintermetallics Powders for tools for industrial manufacturing

VC4Lightweightmultifunctionalmaterialsandcomposites for transportation

Polymeric-based sheets for chassis of cars, trains, trucks, planes, etc.

Figure1-4:Examplesofproducts

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2 Methodology

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Implementation Roadmap on value chains and related pilot lines 7

2 Methodology

The roadmapping activity performed to develop this Implementation Roadmap is a method to produce strategic plans and ideas for future successful development of nanotechnology- based productsrelevantfortheidentifiedfourvaluechains.

Details of the methodology applied are explained in the sections below.

2.1Background–TheNANOfuturesExperience

Value4Nano roadmapping approach is built on the experience and methodology developed by NANOfutures Platform under the previous CSA (grant agreement no 266789). NANOfutures roadmap focused on several value chains, identifying technical and non-technical actions to be performedatshort,mediumorlongterminordertoachievethefinaltarget,i.e.thecommercialisationof sustainable and safe nano-enabled products.

An overall view on the NANOfutures value chains is presented in Figure 2-1.

Figure2-1:OverviewofNANOfuturesvaluechainsandrelatedtargetmarkets

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For each target market, a detailed scheme was built, where technological and non-technological actionswereidentifiedforeachVCstepandfordifferenttimeframes.Ageneralschemeoftheroadmap structure is presented below in Figure 2-2.

Figure2-2:StructureofNANOfutures Value chain based roadmaps

NANOfutures Roadmap underwent a public consultation in Autumn 2012, where associated mem-bers (large and small industries, research centres, universities, associations, etc.), several ETPs, European, National and Regional policy makers validated its outputs and expressed their interests onspecificvaluechains.

Fromtheanalysisofthisconsultation,fourkeyvaluechains(Value4NanoVCs)wereidentified(merging also some of the NANOfutures’ ones) on which to continue the roadmapping activity, looking at:

• Technical and non-technical actions at short (2015-2018), medium (2018-2022) and long term (>2022).

• Specificbusinessmodelling(feasibilitystudies). • Plans for pilot line facilities (quantifying impact of the development of the value chains).

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2.2 Outcome of the Roadmapping Activity

Taking into consideration NANOfutures previous results, a value chain approach was adopted for the Value4Nano project in order to contribute to bridge the current gap (the so-called Valley of Death) between nanotechnology knowledge and successful commercialisation of nano-enabled products, in line with NANOfutures past roadmapping exercises.

Figure 2-3 shows a value chain scheme including some of the factors which may contribute to bridge the gap:

• The availability of technologicalfacilities,pilotlines and globally competitive manu-facturing facilities;

• The outcomes of technological research, the availability of outstanding industrial con-sortia and competitive manufacturing.

Figure 2-3 Value Chain scheme

In order to identify the gaps between knowledge and market, three layers of the value chain were considered:

• The economic chain (i.e. the actual Value Chain); • The technical chain (i.e. the Production Chain); • The societal chain (i.e. the Societal Chain).

For each layer, different “steps” or aspects of the value chain were considered.

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The economic layer of the value chain was divided into the main following steps: ideation,proofofprinciple,businessdevelopment,pre-production,fullmarketandmarketexpansion (see Figure 2-4).

Figure2-4StepsoftheValueChain(economiclayer)

The production chain (technical layer of the value chain) was divided into the following steps: modelling (including design),materials,tools and equipment,metrology,componentsand assembly up to thefinalproduct (see Figure 2-5).

Figure2-5StepsoftheProductionChain(technicallayer)

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Implementation Roadmap on value chains and related pilot lines 11

The societal chain (societal layer of the value chain) was divided into the following aspects: safety,education,standardisation,communication,environmentand regulation (see Figure 2-6).

Figure2-6StepsoftheSocietalChain

Inthiscontexttheoutputofthisprocessconsistedinspecificroadmapsononeormoreclassesof products, including details on possible pilot lines, realised taking into consideration the follow-ing assumptions:

• Gapsareclassifiedintoeconomic,technicalandsocietalones.Foreach,thestepsofthevalue chain are highlighted;

• Actionsareclassifiedintotechnicalandnon-technical.Infacteconomicgapsmaybesolvedwith a set of technical actions or non-technical actions, depending on the type of economic problem.

Suchroadmapscontainactions(technicalandnon-technical)abletosolvetheidentifiedgapsandto achieve the development of the selected class of products.

In this document each Value Chain roadmap is presented and summarised in a graphical scheme, including the proposed actions, the timeline, some representative images of resulting products and the expected resources needed.

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2.3RoadmappingSteps

In this section the process to formulate the roadmaps is explained; Figure 2-7 summarises the steps followed.

(Remote collaboration of VCs, WGs & ETPs)

Figure2-7:SchemeofroadmappingProcess

• Thegapanalysiswasthefirstpartoftheroadmappingprocess(itincludesstepsfrom1to4 detailed in Figure 2-7). The activity was performed through workshops and remote col-laboration (surveys, emails and conference calls);

• Business modelling and planning on pilot lines (steps 5-7) activities were carried out via workshops and remote collaboration (survey, emails and conference calls);

• Roadmaps including pilot lines plans (step 8) were validated through workshops and on-line open consultation approaches.

• For the Dissemination and Exploitation of the roadmapping activity (step 9), a networking event (public) was held at EuroNanoForum 2015 (for wide dissemination) and an Industry Alliance meeting (private, for selected industries) was held on May 2015 (for exploitation purposes).

• Follow up activities (step 10) included regular updates of the roadmaps and monitoring of theupcomingresearchandinnovationactivitiesontheidentifiedvaluechains(e.g.futureEC calls and projects, regional initiatives, etc.).

The following chapters describe in more detail the methodology used for gap analysis, development of actions and pilot feasibility assessment (including business modelling and planning).

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Implementation Roadmap on value chains and related pilot lines 13

2.3.1 Gap Analysis Methodology

Thegapanalysis,thatwasthefirstpartoftheroadmappingactivity,wasdividedintothefollowingsteps:

1. IdentificationofgapsandProductClasses:DuringthefirstVCWorkshop,foreachofthefourVCs,theVCgroup,chairedbytheVCleader,preliminarilyidentifiedalistofclassofproducts relevant for the value chain and a list of most common gaps toward the develop-ment of such products at economic, technical and societal level.

2. Correlation of Gaps and Product Classes: TheVCgroupscorrelatedtheidentifiedgapswith the product classes by means of remote collaborations (e.g. sharing database by emails). A prioritisation of gaps and product classes was then performed: the gaps that could not be correlated with any of the product classes were deleted as well as the product classeswithnoidentifiedgaps.

3. ValidationofpreliminaryfindingsandidentificationofActions:The post-processing of theon-lineroadmappingsurveyenabledthevalidationandrevisionofpreliminaryfindingsintermsofgapsandproductclassesandtheidentificationofactionsatshort,mediumandlong term to solve current gaps.

4. Preliminary Pilot Lines: The post-processing of the online roadmapping survey enabled theidentificationofalistofproductclassesforwhichtoinvestonpilotlinesfacilitiesatEuropean level. These pilot lines were grouped and prioritised, resulting in short list of top pilot lines. The top 4 pilot lines were considered for subsequent feasibility assessment.

2.3.2 Methodology for completion of the actions

The process for the completion of the actions was divided into the following steps

1. Validation of preliminary actions: Thepreliminaryactionsidentifiedduringthegapanaly-sis were carefully revised during the second VC-WG workshop (November 2014). After the meeting VC leaders summarised the contributions leading to an agreed list of action titles, which were included into a spreadsheet, with links among gaps, actions and product classes. For many actions, some draft details were also presented, to be completed by the experts.

2. IdentificationofsynergiesbetweenVCsandotherKETsinitiatives:Synergies between theVCactionsandotherKETsinitiativeswereidentified.Theiranalysisledtosomemodi-ficationstotheproposedactions.

3. FeedbackcollectionbyVCandWGexperts:VC experts and WG participants were asked tocontributeremotelytothefiledescribingindetailactionspecificchallenges,scope,impactand needed economical resources. The WG are groups formed within NANOfutures mem-bers in transversal themes and contribute in evidencing common actions that solves different specificgapsoftheVC.TheWGinvolvedwereIndustrialization&NanomanufacturingandResearch & Technology, for the technological actions, and Communication, Networking, Regulation, Safety, Skills & Education, Standardization and Technology transfer & Innova-tionfinancingforthenon-technologicalactions.

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4. Consolidation of the roadmap actions and graphical representation: Theidentifiedactions were consolidated from the collected feedbacks. A Gantt diagram and a graphical representation were accordingly prepared.

2.3.3 Methodology for pilot lines feasibility assessment (including business modelling and planning)

The process for pilot feasibility assessment (including business modelling and planning) is sum-marised in Figure 2-8. The picture represents the overall methodology followed to identify and characterise the pilot lines.

Figure 2-8: Pilot Line Characterization Process

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Implementation Roadmap on value chains and related pilot lines 15

DuringthefirstVCworkshop,thattookplaceinBrusselsonMarch2014,alistofpotentialpilotlinesandassociatedproductswasidentified.Duringtheprocessofprioritisationandthankstotheon-linequestionnairetowhich200expertsparticipated,aprioritisedlistofpilotswasidentified,as described in Table 2-1:

Table 2-1: List of Pilot Lines

Pilot Line ID Value Chain Associated Products

Pilot Line 1 VC2

• Nanostructuredantimicrobial,antiviralsurfaces(medicaldevices, hospitals, etc.).

• Nanocoatingsformechanicallyenhancedsurfaces(e.g.,abrasion resistance, low friction).

Pilot Line 2 VC4• Lightweightmaterialswithcustomizedthermal/electrical

conductivity properties (e.g. skins of aircrafts for lighting protection, thermal layer, etc.).

Pilot Line 3 VC1

• 3DprintedpolymericmicrofluidicMEMSfornozzlesorfilters,for sensor applications and for multi-use chip (including also injection moulded nanostructures in plastics).

• Labonachip(includingbio-compatibleornon-toxicscaffolds,activeinfluenceofcellgrowth&differentiation).

Pilot Line 4 VC1• Microelectromechanicalsystems-MEMS(includingMicroor

Nano Opto-Electro-Mechanical Systems)• NonmainstreamMEMS.

No pilot line was associated to VC3 since products at the end of this value chain are mostly fed into the others; VC3 is the most transversal area thus contributing to all pilots above.

Each pilot line was then characterised following mainly two methods:

• Deskresearch:reviewofStrategicResearchAgendas,bibliography,scientificliterature,market analyses, etc. This research started during the preliminary stages of analysis prior to the second workshop to gather some general data on the pilot lines and on their associated products (as described in Table 2-1). A review of such analysis was also carried out during the development of the business model.

• Business Model: during the second VC Workshop that took place in Brussels on November 2014 a methodology based on canvas business model was proposed to all participants, divided into Value Chains Working Groups in order to preliminary develop a visual chart with elements describing the pilot lines products value proposition, infrastructure, customers and finances.

These processes led to the description of the proposed four pilot lines, in terms of targeted product classes and related gaps, need for pilot line actions, current TRL, addressed market and list of potential safety risks associated with the deployment of such product classes.

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3 Value Chains Roadmaps

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3 Value Chains Roadmaps

The results of the Gap Analysis contributed to the roadmapping activity schematised in Roadmap Summary Figure 3-2, Figure 3-4, Figure 3-6 and Figure 3-7. In these graphical representations (see the template in Figure 3-1) technical actions are organized in short, medium and long term. Each action is described, in the same representations, with the related value chain step which can be found down in each roadmap scheme (material,modelling,tool,metrologyandassembly). Furthermore, the actions are arranged in a box accompanied by two series of numbers. The se-ries on the right side of action boxes represents the expected TRL, evaluated by the experts from the current TRL during project meeting and workshops. The series on the left side of the boxes describes the link between actions and products. VC1, VC2 and VC4 products are clustered in ordertoobtainaneasy-to-readgraphicalrepresentationsincetheexpertsidentifiedahighnumberof relevant product classes. Groups of products are placed in the last column on the right of each roadmap scheme. The clustering process is schematised in Figure 3-3, Figure 3-5 and Figure 3-8.

Table 3-1, Table 3-3, Table 3-5 and Table 3-7 report a brief description, formulated during the gap-analysis and completion of the action processes, of each VC action. The tables summarise short, medium and long term actions discussed during WGs and VCs experts meetings and by remote collaboration. Validation of these actions was performed during the Industrial Alliance Workshop (May 2015), the on-line survey (May - July 2015) and the Value4Nano/NANOfutures workshop at EuroNanoForum 2015 (June 2015).

The type of action is reported too and it may be IA (Innovation Action), RIA (Research of Innova-tion Action) or CSA (Coordination and Support Action). In the tables, a section is reserved to the TRL (Technology Readiness Level).

The column “Responsible WG” indicates the WG main responsible for the revision of the action. In this case:

• Res = Research and Technology WG • Ind = Industrialization and Nanomanufacturing WG • TT = Technology Transfer and Innovation Financing WG • NT WGs = Non-technical WG (Safety, Standardization, Regulation, Communication and

Networking WGs).

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Figure 3-1: Roadmap Template

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Implementation Roadmap on value chains and related pilot lines 19

3.1 VC1 - Nano and micro printing for industrial manufacturing Roadmap

Figure3-2summarisestheroadmapactivityonVC1.Thefifteenactionselaboratedbytheexpertsare arranged on a timeline and enclosed in boxes reporting the expected TRL and the associated product classes.

Figure 3-2: VC1 Roadmap summary

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Since the experts associated a high total number of product classes to VC1 actions, these are clustered as it can be observed in Figure 3-3, where colours help to distinguish products belonging to different clusters. Products arranged in grey boxes form singular clusters.

Figure 3-3: VC1 Products clustering

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Implementation Roadmap on value chains and related pilot lines 21

Table 3-1 contains a preliminary description of VC1 technical actions. All other cross non-technical actions (affecting each VC) are described in a separate table (Table 4-1).

Complete descriptions of VC1 technical and non-technical actions can be found in Appendices I and V, respectively.

Table3-1:VC1ActionsSummary

Action ID Action Title Type TRL Expected

Responsible WG

VC1-S-001 Demonstrators for non-conventional MEMS (e.g. built with additive manufacturing techniques) & other me-chatronic devices

7 RIA Ind & Res

VC1-S-002 Development and upscale of technologies for low cost lithography for deep submicron (<20nm) ena-bling breakthrough applications in optics and opto-electronics

5-6 RIA Ind & Res

VC1-S-003 Development of 3D printing systems (advanced mate-rial manufacturing approaches, additive manufacturing, metrology and smart software)

5-7 RIA Ind & Res

VC1-S-004 Surface functionalization by structuration in injection moulding, embossing technologies and roll to roll

5-7 RIA Res

VC1-S-005 Development of novel extrusion techniques at high TRL

6-8 VC1-S-005 comes from the online survey and has to be intended as a suggestion for further actions

VC1-S-006 Combinatorial approaches (mass parallel screening of material properties) to develop materials with new functionalities combining chemical composition, nano size and shape effect

5 RIA Res

VC1-M-001 Development and enhancement of inspection technol-ogies and methods for nanostructures over large areas

7-8 RIA Ind & Res

VC1-M-002 Enhanced interfaces to improve solid–gas, solid–liquid, and liquid-gas interactions for breakthrough applica-tions

6 RIA Res

VC1-M-003 Industrial oriented research and demonstration on injection moulding of polymeric-based products with nanostructured functionalized surfaces

7 RIA Ind & Res

VC1-M-004 Ultra-high barrier technologies for flexible organic based printed technologies/devices (i.e. OLED, OPV, OTFT)

7-8 RIA Ind & Res

VC1-L-001 Breakthrough Hybrid smart materials & systems 6-7 RIA Res

VC1-L-002 New generation of disruptive injection moulding ma-chines

7 RIA Ind

VC1-L-003 Development of customized solutions for printing pro-cesses

5-6 VC1-L-003 and VC1-L-004 come from the online sur-vey and have to be in-tended as a suggestion for further actions

VC1-L-004 Development and upscaling of 3D processes (e.g. direct laser writing and stereolithography) for more complex nanotructured components, for a breadth of applications e.g. health and PV

5-6

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3.1.1 VC1 Impact

Table 3-2 summarises VC1 expected impact on society distinguishing from industrialleadership,examplesofproducts,societalImpact,excellenceinscience, and benefitforSMEs.

Table3-2:VC1ExpectedImpact

Value chain impact

Industrial Leadership in targetmarkets(fromRoc-

KET7markets)

• ElectronicsandCommunicationSystems• Chemicalprocesses,chemicals,chemicalproductsandmaterials• Manufacturingandautomation(includingrobotics)

OLED MEMS 3DPRINTEDCOMPONENTS

SocietalImpact(fromSocietalChallengesof

Horizon 20208)

• Europeinachangingworld-inclusive,innovativeandreflectivesocieties;

• Health,demographicchangeandwellbeing;• Secure,cleanandefficientenergy;• Climateaction,environment,resourceefficiencyandrawmaterials.

ExcellentScience

• Contributingtobridgethecurrentgapbetweenadvancedlabresearch and market;

• Progressinindustrialresearchonbreakthroughapplications;• Improvementsinthetechnologicalbaseandthecompetitivenessof

Europeanindustry;especiallyforinnovationfieldswhichshowhigheconomic potential for the use of micro and nanotechnologies;

• EnablingEuropetocompeteattheforefrontofthe3Dmanufacturing revolution;

• Newtoolsformetrologyanddefectinspectionoverlargeareaswill:· Enable benchmarking of the functionalities of the available

nanomaterials;· Enableinvestigatingtheexactspecificationsofnanomaterials

required for the application;· Let Europe to keep its leading position in the production of

advanced lithography equipment and the Inspection equipment; · Provide a natural complement to advanced lithography and

inspection equipment.

BenefitforSMEs

• EnablingmanufacturingactivitiesbySMEstoentermarketswithinnovations that were not possible before;

• EnablingEuropetocompetewithhighaddedvalueproductssuchMEMS and mechatronic devices;

• Contributingtoreinforceentiremanufacturingvaluechainstartingform tools manufactures to good producers to end-users;

• Moresustainablemanufacturingofadvancedstructuresandcomplex geometries when compared to current average values

· Reduction of at least 20% in the overall energy consumption; · Reduction of at least 20% in the material usage.

7 http://ec.europa.eu/growth/industry/key-enabling-technologies/eu-actions/ro-ckets/index_en.htm8 https://ec.europa.eu/programmes/horizon2020/en/h2020-section/societal-challenges

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3.2.VC2-Nano-enabled,depollutantandself-cleaningsurfacesRoadmap

Figure 3-4 summarises the roadmap activity on VC2. The twelveactions elaborated by the experts are arranged on a time lime and enclosed in boxes reporting the expected TRL and the associated product classes.

Figure 3-4: VC2 Roadmap summary

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Since the experts associated a high total number of product classes to VC2 actions, these are clustered as it can be observed in Figure 3-5, where colours help to distinguish products belonging to different clusters. Products arranged in grey boxes form singular clusters.

Figure 3-5: VC2 Products clustering

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Table 3-3 contains a preliminary description of VC2 technical actions. All other cross non-technical actions (affecting each VC) are described in a separate table (Table 4-1).

Complete descriptions of VC2 technical and non-technical actions can be found in Appendices II and V, respectively.

Table3-3:VC2ActionsSummary

Action ID Action Title Type TRL Expected

Responsible WG

VC2-S-001 Advanced industrial research to enhance the performance of functional nanocoatings

RIA 7-8 Ind

VC2-S-002 Pilot Lines for the manufacturing and/or functionalization of nanosurfaces for novel applications

RIA 7 Res & Ind

VC2-S-003 Novel processes and technologies for engineering surfacemodificationandfunctionalitiesincorporation

IA 6-7 Ind

VC2-S-004 Advanced research and demonstration on nanostructured surfaces for renewable energy production

RIA 6-7 Res

VC2-M-001 Large scale demonstrators on the use of nano-enabled surface technologies for clean air, water and energy with involvement of European municipalities

IA 7 Ind

VC2-M-002 Environmental friendly processes to activate functional nano-surfaces and to incorporate nanoparticles

RIA 6 NT WGs; Ind & Res

VC2-M-003 Supportinnovativenewtechnologiesforefficienthandling and manipulation of nanoparticles

CSA 6 TT &Res

VC2-M-004 Development of sustainable processes for in-line treatment to produce nano-based antimicrobial, antifungal surfaces

RIA 6-7 TT

VC2-L-001 Research on antimicrobial surfaces active under visible light

RIA 7 Res

VC2-L-002 Increase the durability of nanocoatings in order to supply traditional industries with affordable added value products

RIA 7 Ind

VC2-L-003 Networking and coordination activities to promote certificationofrawnanomaterialsthroughoutthewhole manufacture chain in the production of waterandairpurificationsystem

CSA NA NT WGs

VC2-L-004 Smart handling interactions of parts/components with sensitive nano-enabled surfaces

RIA NA NA

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3.2.1 VC2 Impact

Table 3-4 summarises VC2 expected impact on society distinguishing from industrialleadership,examplesofproducts,societalimpact,excellenceinscience,andbenefitforSMEs.

Table3-4:VC2ExpectedImpact

Value chain impact

Industrial Leadership in target markets

(from Roc-KET 9 markets)

• Chemicalprocesses,chemicals,chemicalproductsandmaterials• Manufacturingandautomation• Textiles• Environment(includingwatersupply,sewerage,wastemanagement

and remediation)• Civilsecurity(includingdualuseapplications)• Healthandhealthcare• Energy(includingenergygeneration,storage,transmissionand

distribution)

Nanostructured coatings for UV screening (e.g., cosmetics, sun-screen protection, etc.)

Nanostructured surfaces with antimicrobial, antiviral, biocompatible, anti-adhesive properties for biomedical applications (e.g., medical devices, implants, hospital rooms, etc.)

Nanostructured coatings for thermal management (e.g., coolingandIRreflection)

Societal Impact (from Societal Challenges of

Horizon 202010 )

• Europeinachangingworld-inclusive,innovativeandreflectivesocieties;• Health,demographicchangeandwellbeing;• Secure,cleanandefficientenergy;• Climateaction,environment,resourceefficiencyandrawmaterials;• Securesocieties-protectingfreedomandsecurityofEuropeandits

citizens.

Excellent Science

• Integrationofstate-of-the-artnanotechnologyinthetraditionalproduction of coatings/surfaces will give a market advantage to the European coatings sector via the development of functional nanocoatings (e.g., super hydrophobic, anti-pollutant, antimicrobial/antiviral, corrosion/abrasion resistant, self-healing, highly selective, anti-reflection,luminescent,etc.)

• Higherlevelofautomationandlowerproductiontimescomparedtocurrent technologies;

• Potentialreductionincarbondioxide(CO2) emissions;• Improvementintechnicalknowledgeconcerningmanufacturing

processes of surfaces;• Significantreductioninthecostofrenewableenergy.

BenefitforSMEs

• IncreasethecompetitivenessofEuropeanSMEsengagedinenvironmental, biomedical, textile, automotive sectors, etc.

• Energyefficientandsafeproductionprocesses;• Eliminationofexpensiveandtime-consumingpost-productionprocesses;• Newmarketopportunitiesviaintroductionofanovelprocessinexisting

production lines;• OpportunitiesforboostingSMEsbusinessastechnologyproviders.

9 http://ec.europa.eu/growth/industry/key-enabling-technologies/eu-actions/ro-ckets/index_en.htm10 https://ec.europa.eu/programmes/horizon2020/en/h2020-section/societal-challenges

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3.3VC3-Manufacturingofpowdersmadeoffunctionalalloys,ceramics and intermetallics Roadmap

Figure 3-6 summarises the roadmap activity on VC3. The ten actions elaborated by the experts are arranged on a time lime and enclosed in boxes reporting the expected TRL (on the left in this case) and the associated product classes (on the right).

VC3hasnoproductclusteringfigurebecauseinthiscasethenumberoffinalproductclassesidentifiedbytheexpertswasalreadyrestrained,allowingaplainroadmapgraphicalschematisation.

Figure 3-6: VC3 Roadmap summary

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Table 3-5 contains a preliminary description of VC3 technical actions. All other cross non-technical actions (affecting each VC) are described in a separate table (Table 4-1).

Complete descriptions of VC3 technical and non-technical actions can be found in Appendices III and V, respectively.

Table3-5:VC3ActionsSummary

Action ID Action Title Type TRL Expected

Responsible WG

VC3-S-001 Modellingtoolsformicrofluidicbehaviourofnanoparticlesand/oradvancedfluids 5-6 RIA Res

VC3-S-002 Costeffectiveindustrialscaletechnologiesforfillersynthesis and technologies for dispersion 5-6 RIA Ind

VC3-S-003Reactive/In Situ /In process generation of the nano-features as large scale, low cost source of nanomaterials

6-7 RIA Ind & Res

VC3-M-001Simulations and proof of concepts on materials for energy storage (e.g. materials for natural gas storage)

5 RIA Res

VC3-M-002 Development of new nanomaterials as substitutions of Critical Raw Materials (CRMs) 5 RIA Res & NT

WGs

VC3-M-003 Development of materials for indoor air quality control / Prototype 5-6

VC3-M-005 comes from the online survey and has to be intended as a suggestion for further actions

VC3-L-001Developing joint interdisciplinary experimental platforms, including virtual platforms, with open access for SMEs

7 IA NT WGs

VC3-L-002

Development of new comprehensive methods and multiscale modelling across full value chains to design new nano-related materials or to increase their TRL

7 RIA Ind &Res

VC3-L-003 Synthesis of 'hosted' nano particle systems for nanomedicine 6-7 RIA Res

VC3-L-004 Development of tools for indoor air quality control / Prototype 5

VC3-L-004 comes from the online survey and has to be intended as a suggestion for further actions

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3.3.1 VC3 Impact

Table 3-6 summarises VC3 expected impact on society distinguishing from industrialleadership,examplesofproducts,societalimpact,excellenceinscience, and benefitforSMEs.

Table3-6:VC3ExpectedImpact

Value chain impact

Industrial Leadership in target markets

(from Roc-KET11 markets)

• Chemicalprocesses,chemicals,chemicalproductsandmaterials• Manufacturingandautomation• Textiles• ElectronicsandCommunicationSystems• Environment(includingwatersupply,sewerage,wastemanagement

and remediation)• Healthandhealthcare• Civilsecurity(includingdualuseapplications)• Energy(includingenergygeneration,storage,transmissionanddistribution)

Societal Impact (from Societal Challenges

of Horizon 202012 )

• Europeinachangingworld-inclusive,innovativeandreflectivesocieties;• Health,demographicchangeandwellbeing;• Secure,cleanandefficientenergy;• Climateaction,environment,resourceefficiencyandrawmaterials.

Excellent Science

• Definitionofguidelinesandreferencecasesthatcontributetothediffusionandadoptionofthemicrofluidictechnology;

• Improvementintechnicalknowledgeontheintegratedmanufacturingprocesses for nanomaterials in terms of productivity and cost-effectiveness.

Benefit for SMEs

• Significantimprovementsinindustrialproductivity,reliability,safetyandcost competitiveness in comparison with traditional processes;

• Supplyoflowcost,highperformanceandenvironmentallyfriendlynanomaterials dispersed in proper matrix as master batches, allowing Europeanmanufacturerstoexploitthegreatgrowthopportunityinthisfield;

• Demonstratedincreaseddegreeofcompatibilityofadvancedreactivematerials with existing production lines, leading to higher production volumes, improved reliability and repeatability of produced nano enabled product and lower production cost;

• Reducethetimetomarketofnovelsystemsfornanomedicine;• EnhanceEuropeancompetitivenessinPharmaceuticalIndustry.

11 http://ec.europa.eu/growth/industry/key-enabling-technologies/eu-actions/ro-ckets/index_en.htm12 https://ec.europa.eu/programmes/horizon2020/en/h2020-section/societal-challenges

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3.4VC4-Lightweightmultifunctionalmaterialsandcompositesfor transportation Roadmap

Figure 3-7 summarises the roadmap activity on VC4. The eleven actions elaborated by the experts are arranged on a time line and enclosed in boxes reporting the expected TRL and the associated product classes.

Figure 3-7: VC4 Roadmap summary

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Since the experts associated a high total number of product classes to VC4 actions, these were clustered as it can be observed in Figure 3-8, where colours help to distinguish products belonging to different clusters. Products arranged in grey boxes form singular clusters.

Figure 3-8: VC4 Products clustering

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Table 3-7 contains a preliminary description of VC4 technical actions. All other cross non-technical actions (affecting each VC) are described in a separate table (Table 4-1).

Complete descriptions of VC4 technical and non-technical actions can be found in Appendices IV and V, respectively.

Table3-7:VC4ActionsSummary

Action ID Action Title Type TRL Expected

Responsible WG

VC4-S-001Scouting of enabling manufacturing techniques to scale up innovative productions through the Identificationofbreakthroughmarketmodels

CSA NA TT

VC4-S-002 Development of hybrid LCA/LCC and FE modelling techniques for smart lightweight composites RIA 5-6 Res

VC4-S-003Layered Composites Material based on foam, functional nanolayers, and new joining technologies as energy saving solutions

RIA 5-6 Ind & Res

VC4-S-004 Composite or Hybrid Multifunctional Materials and Systems RIA 5-6 Ind & Res

VC4-S-001Scouting of enabling manufacturing techniques to scale up innovative productions through the Identificationofbreakthroughmarketmodels

NA CSA TT

VC4-S-002 Development of hybrid LCA/LCC and FE modelling techniques for smart lightweight composites 5-6 RIA Res

VC4-S-003Layered Composites Material based on foam, functional nanolayers, and new joining technologies as energy saving solutions

5-6 RIA Ind & Res

VC4-S-004 Composite or Hybrid Multifunctional Materials and Systems 5-6 RIA Ind & Res

VC4-S-005 Development of dedicated tribometers for characterization and testing 1-2

VC4-S-005 comes from the online survey and has to be intended as a suggestion for further actions

VC4-M-001Integrated European web-based Platform for advanced composite materials processing, characterization and standards (JRC-like)

NA CSA Res & NT WGs

VC4-M-002

Innovative manufacturing equipment for advanced nano-integrated materials (e.g. on-line characterization controls and operational standards compliance evaluation)

7-8 RIA Ind & TT

VC4-M-003 Advanced techniques for experimental assessment of nano-materials properties 3-6 RIA Res & NT

WGs

VC4-M-004Prototype development of materials combining customized thermal/ electrical/ aesthetic and/or (photo)catalytic properties

5-6

VC4-M-004 comes from the online survey and has to be intended as a suggestion for further actions

VC4-L-001 integration among industrial and research know-how NA CSA Ind; NT WGs;

TT & Res

VC4-L-002Encourage stronger industrial environment of cooperation and culture of funding for development of forthcoming technologies

NA CSA Ind; NT WGs; TT & Res

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3.4.1 VC4 Impact

Table 3-8 summarises VC4 expected impact on society distinguishing from industrialleadership,examplesofproducts,societalImpact,excellenceinscience, and benefitforSMEs.

Table3-8:VC4ExpectedImpact

Value chain impact

Industrial Leadership in target markets

(from Roc-KET13 markets)

• ElectronicsandCommunicationSystems• Chemicalprocesses,chemicals,chemicalproductsandmaterials• Manufacturingandautomation(includingrobotics)• Energy(includingenergygeneration,storage,transmissionanddistribution)• Construction• Transportandmobility• Environment(includingwatersupply,sewerage,wastemanagementand

remediation)• Healthandhealthcare• Textiles

Multifunctional ma-terials with embed-ded electronics

Lightweight batteries includ-ing their packaging (e.g. for electrical vehicles or vehicles with high electrical storage needs)

Materials with anti-corro-sion properties (e.g. tanks for transportation of UREA or for fuel distribution)

Societal Impact (from Societal Challenges of

Horizon 202014 )

• Health,demographicchangeandwellbeing;• Secure,cleanandefficientenergy;• Smart,greenandintegratedtransport;• Climateaction,environment,resourceefficiencyandrawmaterials;• Europeinachangingworld-inclusive,innovativeandreflectivesocieties;• Securesocieties-protectingfreedomandsecurityofEuropeanditscitizens

Excellent Science

• Definitionofguidelinesandreferencecasesthatcontributetodevelopmentofbusiness plans that encourage private sector investment for future business growth;

• Demonstratedscaling-upandincreaseddegreeofautomationofmultifunctional material production lines/processes, leading to higher production volumes, improved reliability and repeatability of produced multifunctional materials and lower production cost;

• Contributiontoimprovedresourceefficiency,safetyandenvironmentalfriendliness of adoption of the multifunctional materials and related products (e.g. aiming at fully recyclable products);

• Inlinequalitycontrolofproductpropertiestechniquesforvolumetricmultiscale characterization of nanocomposites

13 http://ec.europa.eu/growth/industry/key-enabling-technologies/eu-actions/ro-ckets/index_en.htm14 https://ec.europa.eu/programmes/horizon2020/en/h2020-section/societal-challenges

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Value chain impact

Benefit for SMEs

• Thedirectandsustainableimpactofthisactionwillbetoreducethegapbetween SMEs, science research around industrial advanced technologies for innovative materials and market requirements, in order to promote scale-up productions, compliant and aligned with global challenges;

• ContributiontoenhanceSMEs’competitivenessbymeansofvaluablebusiness plans drawing as a main outcome the hints needed for entering new markets and being competitive on a wide scale;

• ContributiontoachievingEUpoliciesinviewoffundingdeploymentsinsupport of SMEs addressed in the project;

• SupporthightechSMEsastechnologyprovidersfornanotechnologybasedprocessing

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4 Cross-cutting non-technical actions

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4 Cross-cutting non-technical actions

In this section, the result of V4N participants brainstorming on non-technical aspects of roadmap-ping is presented.

Figure 4-1 illustrates the roadmap activity for cross-cutting non-technical actions (affecting each VC); these are organised in short, medium and long term and allocated to different areas (Regu-lation, Environment, Education, Standardization and Safety), that are represented with different colours as in the key.

Figure 4-1: Non-technical actions roadmap summary

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology38

Table4-1brieflyreportsthedescriptionthattheexpertsmadeduringthegap-analysisandcomple-tion of the actions processes, for non-technical actions in terms of affected VCs, action ID, action title, type (CSA, RIA, IA), TRL (if any) and responsible Working Groups. The complete description of Value4Nano non-technical actions can be found in Appendix V.

Table4-1:Non-TechnicalActionsSummary

Value Chain Action ID Action Title Type TRL

Expected Responsible WG

ALL NT-S-001

Networking, sharing best practices and promoting harmonized methodologies such as standards or other authoritative guidelines on managing nanomaterials and related products along their life cycle

CSA NA NT WGs

ALL NT-S-002

Promotion of effective communication on nano, fromdefinitionofnanotonanolabelling and nano-related risksandbenefits

CSA NA NT WGs

ALL NT-S-003

EU and International Cooperation for development and promotion of effective, practicable and low cost toxicology testing methods

RIA 7 NT WGs

VC1, VC2, VC3

NT-S-004

Promoting education, training activities and industry-academia exchanges on nanostructured surfaces and nanocoatings

CSA NA NT WGs

ALL NT-S-005Proof of concept of safety risk assessment and management on pilot line products

RIA 7 NT WGs (Safety; Standardization)

ALL NT-S-006 Bringing nanotechnology to more traditional sectors CSA NA NT WGs (Networking;

Communication)

ALL NT-S-007 Improved communication skills for nano-experts CSA NA

NT WGs (Networking; Communication; Skills & Education)

ALL NT-S-008 Industry outreach to university training CSA NA NT WGs (Networking;

Skills & Education)

ALL NT-S-009

Provide industry feedback on the elements of a meaningful regulatorydefinitionofnanomaterials

NA NA NT WGs (Regulation)

ALL NT-S-010

Cooperation for developing suitable methods to avoid costly misunderstandings between lab level and industry user level concerning nano-related materials and processes

NA NA NT WGs (Standardization)

ALL NT-M-001

Harmonization and standardization of protocols and development of a working agenda for education and training on real-life scenarios in several sectors

CSA NA

NT WGs (Skills & Education; Communication; Networking)

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Implementation Roadmap on value chains and related pilot lines 39

Value Chain Action ID Action Title Type TRL

Expected Responsible WG

ALL NT-M-002

Exploitation and dissemination ofbestpracticesinthefieldofpublic co-funded projects in nanotechnology

CSA NANT WGs (Networking; Communication; Skills & Education; Safety)

ALL NT-M-003Cross-sectorial Technology Transfer program in the NMP field

CSA NATT; NT WGs (Networking, Communication)

ALL NT-M-004

Effective communication and dialogue with the EU society on the social and economic impact of nano

CSA NATT; NT WGs (Communication; Networking; Safety)

VC2, VC3 NT-M-005

Implementation of standardization methods for characterizing and/or performance validation of nanoparticles

RIA NA TT; NT WGs (Networking; Communication)

ALL NT-M-006

Establishment of a Platform where all Best Available Technologies (BAT) in the corresponding PILOTS are assessed.

NA NA TT; NT WGs (Skills & Education)

ALL NT-M-007Responsible research and Innovation (RRI) as a cross-cutting issue in H2020

CSA NA NA

ALL NT-M-008 Promoting more Horizon 2020 calls NA NA NA

ALL NT-M-009

Promotion of effective communication, education, training and industry-academia exchanges

NA NA NA

ALL NT-M-010

Coordinated Technology scouting to identify Research results with relevant upcoming advanced materials for application and scale up to Pilot production

NA NA NA

ALL NT-L-001New business strategies and business models for nano-enabled products

CSA NATT; NT WGs (Networking; Communication)

ALL NT-L-002Education on Marketing and Communication Skills in NMP field

CSA NATT; NT WGs (Skills & Education; Networking; Communication)

VC2, VC3 NT-L-003

Joint EU & MS activity to support EU nano-regulation with focus on nanoparticles <5nm

CSA NANT WGs (Regulation; Standardization; Research; Safety)

ALL NT-L-004

EU and International Cooperation for the development of added-value, low cost and eco-friendly nano-related products adopting "safety by design" approach

CSA NANT WGs(Safety; Standardization; Research)

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology40

4.1 Non-technical actions Impact

The present roadmap will contribute to address the Societal Challenges as mentioned in Horizon 2020. The path from Societal Challenges to markets and products towards implementation of specificnon-technicalactionsisshowninFigure4-2.

Figure4-2:FromSocietalChallengestoproductstowardsproposedactions

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Implementation Roadmap on value chains and related pilot lines 41

In Figure 4-3 an example of the possible path to address the Societal Challenges called “Clean andefficientEnergy”,“Greentransport” and “Climateaction,resourceefficiencyandrawmaterials” is given.

Figure4-3:Exampleofpathtowardaddressing“CleanandefficientEnergy”,“Greentransport”and“Climateaction,resourceefficiencyandrawmaterials”Societal

Challenges

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5 Pilot Lines Roadmaps

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Implementation Roadmap on value chains and related pilot lines 43

5 Pilot Lines Roadmaps

For each pilot line, VC experts discussed, planned and validated a number of technical and non-technical actions during the Industry Alliance meeting (May 2015) and EuroNanoForum 2015 (June 2015).

The following paragraphs summarise the accomplished roadmapping activity, which includes tech-nical and non-technical actions divided by short, medium and long term and a summary of the efforts carried out by the experts during the Industrial Alliance to estimate and evaluate the interest that the community demonstrates on the presented pilot lines.

For each pilot line a risk analysis was also developed, focusing on health and environment pilot linesspecificrisks.

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology44

Figure 5-1: Pilot Lines Roadmap summary

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Implementation Roadmap on value chains and related pilot lines 45

5.1 PilotLine1–Nanostructuredsurfacesandnanocoatings

In the following paragraphs VC2 Pilot Line 1 - Nanostructured surfaces and nanocoatings techni-calandnon-technicalactionsarebrieflydescribed.Pilotline1businessplansaredescribedtoo,togetherwiththeexamplesofpossibleconsortiastructuresandaspecificriskanalysis.TheflagT/NTinthefirstcolumnofTable5-1detailswhethertheactionistechnicalornon-technical.

5.1.1 PilotLine1a-Nanostructuredantimicrobial,antiviralsurfacesformedicaldevices,hospitals,etc.

Table5-1brieflydescribesPilotLine1atechnicalandnon-technicalactionsintermsofrelatedVC,ActionTitleandID,ActionType,expectedTRLandresponsibleWorkingGroups.TheflagT/NTinthefirstcolumnofTable5-1detailswhethertheactionistechnicalornon-technical.

Table5-1:PilotLine1aActionsSummary

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

T VC2 VC2-S-001Advanced industrial research

to enhance the performance of functional nanocoatings

RIA 7-8 Ind

T VC2 VC2-S-002Pilot Lines for the manufacturing and/or functionalization of nano-surfaces for novel applications

RIA 7 Res & Ind

T VC2 VC2-M-002

Environmental friendly processes to activate functional nano-surfac-es and to incorporate nanoparti-

cles

RIA 6 Ind, Res & NT WGs (Safety)

T VC2 VC2-L-001 Research on antimicrobial sur-faces active under visible light RIA 7 Res

NT ALL NT-S-001

Networking, sharing best prac-tices and promoting harmonized

methodologies such as standards or other authoritative guidelines on managing nanomaterials and related products along their life

cycle

CSA NANT WGs (Standardiza-tion; Networking; Com-munication; Regulation)

NT ALL NT-S-002

Promotion of effective communi-cationonnano,fromdefinitionofnano to nanolabelling and nano-

relatedrisksandbenefits

CSA NA

NT WGs (Communica-tion; Safety; Network-ing; Regulation; Skills

and Education)

NT ALL NT-S-003

EU and International Cooperation for development and promotion of effective, practicable and low cost

toxicology testing methods

RIA 7NT WGs (Safety; Net-working; Standardiza-

tion; Regulation)

NTVC1, VC2, VC3

NT-S-004

Promoting education, training activities and industry-academia exchanges on nanostructured

surfaces and nanocoatings

CSA NA NT WGs (Skills & Edu-cation)

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology46

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

NT ALL NT-S-005Proof of concept of safety risk

assessment and management on pilot line products

RIA 7 NT WGs (Safety; Stand-ardization)

NT ALL NT-M-001

Harmonization and standardiza-tion of protocols and development of a working agenda for education and training on real-life scenarios

in several sectors

CSA NANT WGs (Skills & Edu-cation; Communication;

Networking)

NT ALL NT-M-002

Exploitation and dissemination of bestpracticesinthefieldofpublicco-funded projects in nanotech-

nology

CSA NANT WGs (Networking;

Communication; Skills & Education; Safety)

NT ALL NT-M-003 Cross-sectorial Technology Trans-ferprogramintheNMPfield CSA NA

TT & NT WGs (Net-working, Communica-

tion)

NT ALL NT-M-004

Effective communication and dialogue with the EU society on the social and economic impact

of nano

CSA NATT & NT WGs (Com-

munication Networking; Safety)

NT VC2, VC3 NT-M-005

Implementation of standardiza-tion methods for characterizing

and/or performance validation of nanoparticles

RIA NA TT & NT WGs (Net-

working; Communica-tion)

NT ALL NT-L-001New business strategies and

business models for nano-ena-bled products

CSA NATT & NT WGs (Net-

working; Communica-tion)

NT ALL NT-L-002Education on Marketing and

Communication Skills in NMP field

CSA NATT & NT WGs (Skills & Education; Networking;

Communicatio

NT VC2, VC3 NT-L-003

Joint EU & MS activity to support EU nano-regulation with focus on

nanoparticles <5nmCSA NA

NT WGs (Regulation; Standardization; Re-

search; Safety)

NT ALL NT-L-004

EU and International Cooperation for the development of added-

value, low cost and eco-friendly nano-related products adopting

"safety by design" approach

CSA NA NT WGs (Safety; Stand-ardization; Research)

The complete description of Pilot Line 1a technical and non-technical actions can be found in Ap-pendices II and V, and an overall description of Pilot Line 1a can be found in Appendix VI.

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Implementation Roadmap on value chains and related pilot lines 47

Table 5-2 explains Pilot Line 1a Business Model developed from VC Experts and stakeholder con-tributions during the Second Value Chain Workshop with a methodology based on canvas models.

Table 5-2: Pilot Line 1a Business Plan

Key

Par

tner

sK

ey A

ctiv

ities

Valu

e Pr

opos

ition

Cus

tom

er R

elat

ions

hip

CustomerSegments

•Raw

materialsuppliers

•Technologyproviders

•R&Dcentersanduniversities

•Deliverypartners

•Regulatoryagents

•R&Dandmaterialdesign

•Produ

ctionan

dqu

alityas-

sess

men

t•Processcontrol

•Testingandvalidation

•LC

A,LCC

•Certification,regulationand

stan

dard

isat

ion

•Training

•Com

munication

•Ade

quateassessmen

tan

dm

anag

emen

t of r

isks

to h

ealth

an

d en

viro

nmen

t in

clud

ing

LCA

•Lowcost,multifunctionalm

a-te

rials

with

enh

ance

d sa

fety

an

d lo

nger

ope

ratio

nal l

ife-

time.

Sui

tabl

e fo

r ret

ro-tr

eat-

men

ts.

•Addingphotocatalyticnano-

parti

cles

to h

te a

ir de

cont

ami-

natio

n sy

stem

, th

e sy

stem

w

ould

hav

e th

e ad

vant

age

of

dest

roy

mic

robe

s w

hile

de-

com

posi

ng V

OC

s w

ithou

t the

m

ajor

pre

ssur

e dr

op a

ssoc

i-atedtothetraditionalfiltration

proc

esse

s.

•Keyaccountmanagem

ent

•Majordiscountsforinstallers

•Trialofthesystems

•Hospital,cleanrooms,quaran-

tine

room

s•Pha

rmaceu

ticalprodu

ction

proc

esse

s•Microand

nan

o-electron

ic

prod

uctio

n pr

oces

ses

•SolarPVandwindenergy

•OEMim

plantabledevice

•Fuelcell

•Oilandgas

•Transport

•Construction

•Culturalheritage

•Municipality

•Upholstery

Key

reso

urce

sC

hann

els

•Skilledpersonnel

•Softwaremodellingan

das

-se

ssm

ents

•IP

•Uniquebrandpositioning

•Networking

•Financialresources

•Internetpresence

•Scientificandtechnicaljour-

nals

•Participationinconferences

and

trade

fairs

•Insitudem

onstration

•Directsale

•Retailpartnerships

CostS

tructure

RevenueStreams

•Salaries

•R&D&I

•Raw

materials

•Production&assem

bly

•Facitiliesandequipm

ent

•Sterilisation

•Packaginganddistribution

•Marketingandsales

•Businessdevelopm

ent

•Productsales

•Individualproductunitssale,asanextrainourAHUs,asanextraforo

ur

com

petit

ors

AH

Us

•Productmaintenance

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology48

Table 5-3 shows examples of possible consortia structures that were developed around Pilot Line 1a during the Industrial Alliance Workshop. These consortia structures help to evaluate the indus-trialprofitabilityofproductsandservicesproposedtobedeveloped.

Table5-3:PilotLine1a-ExamplesofpossibleConsortiaStructures

VCSTEP PROPOSEDACTIVITY NEEDEDPARTNERHIPS

MATERIAL

Dispersion of nanomaterials in metal/polymer matrices

Materials technology & development: R&D centres; Spin-off companies; SMEs

Customized alloys for antimicrobial coating in metallic or polymer/ resin (TRL 3-5) Expert consultants

Pilot line for low cost metallic and metal oxide lowmicron(>5μm)sub-micronandnanoparticlesAntimicrobial coatings based on nanocapsules orultra-thinfilms(TRL4-6)Coating at TRL 4 (validated with respect to bio-compatibility and antimicrobial properties)

TOOL

Research technology Surface coatings technology (e.g., nanolayer, plasma): Research centres, spin-offs, SMEs

Process for triple layer adhesive / non-adhesive coating for implants Expert consultants

Plasma technology (atmospheric) for improve-ment, enhancement, activation, functionalization, nanocoating of surfaces before antimicrobial products application (TRL 6-8)

Suppliers of equipment for spe-cialty surface coatings (e.g., ul-trasound coating equipment): companies

Large-scale, low-cost, customized environmental friendly surface coating technology for a large range of applications: self-cleaning, hydropho-bic, anti-microbial fabrics or other substances for medical applications and construction

Expert personnel

Ultrasound spray coating equipment for en-hanced surface nanocoatings (antimicrobial, hydrophobic, self-cleaning properties)

Expert consultants

Plasma equipment personnel Broadcasting expertsProcessqualification Sensoring providersOngoing collaboration with industrial partner spe-cialized on biological tests Modelling experts

Dissemination & Exploitation Broadcasting experts

ASSEMBLY Large corporations with integrators role

FINAL PRODUCT

Manufacturing facilitiesScale up facilities

Production plant (industrial part-ner)

Productqualification End users for product validation and exploitation

Multifunctional non-woven textile for cars (anti-fungal) carpetsAntibacterial/antifungal textile

Specialty textiles manufacturers

LCA/LCC and risk assessment/management Life Cycle and Life Cost Analysts

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Implementation Roadmap on value chains and related pilot lines 49

5.1.2 Pilot Line 1b - Nanocoatings for mechanically enhanced surfaces

Table54brieflydescribesPilotLine1btechnicalandnon-technicalactionsintermsofrelatedVC,ActionTitleandID,ActionType,expectedTRLandresponsibleWorkingGroups.TheflagT/NTinthefirstcolumnofTable54detailswhethertheactionistechnicalornon-technical.

Table5-4:Pilot1bActionsSummary

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

T VC2 VC2-S-001 Advanced industrial research to enhance the performance of

functional nanocoatings

RIA 7-8 Ind

T VC2 VC2-S-002 Pilot Lines for the manufacturing and/or functionalization

of nanosurfaces for novel applications

RIA 7 Res & Ind

T VC2 VC2-L-001 Research on antimicrobial surfaces active under visible light

RIA 7 Res

NT ALL NT-S-001 Networking, sharing best practices and promoting

harmonized methodologies such as standards or other authoritative guidelines on

managing nanomaterials and related products along their life

cycle

CSA NA NT WGs (Standardization;

Networking; Communication;

Regulation)

NT ALL NT-S-002 Promotion of effective communication on nano, fromdefinitionofnanoto

nanolabelling and nano-related risksandbenefits

CSA NA NT WGs (Communication;

Safety; Networking; Regulation; Skills and

Education)NT ALL NT-S-003 EU and International Cooperation

for development and promotion of effective, practicable and low cost toxicology testing methods

RIA 7 NT WGs (Safety; Networking;

Standardization; Regulation)

NT VC1, VC2, VC3

NT-S-004 Promoting education, training activities and industry-academia exchanges on nanostructured

surfaces and nanocoatings

CSA NA NT WGs (Skills & Education)

NT ALL NT-S-005 Proof of concept of safety risk assessment and management on

pilot line products

RIA 7 NT WGs (Safety; Standardization)

NT ALL NT-M-001 Harmonization and standardization of protocols

and development of a working agenda for education and

training on real-life scenarios in several sectors

CSA NA NT WGs (Skills & Education;

Communication; Networking)

NT ALL NT-M-002 Exploitation and dissemination ofbestpracticesinthefieldofpublic co-funded projects in

nanotechnology

CSA NA NT WGs (Networking; Communication; Skills & Education; Safety)

NT ALL NT-M-003 Cross-sectorial Technology Transfer program in the NMP

field

CSA NA TT & NT WGs (Networking,

Communication)

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology50

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

NT ALL NT-M-004 Effective communication and dialogue with the EU society on the social and economic impact

of nano

CSA NA TT & NT WGs (Communication;

Networking; Safety)

NT VC2, VC3

NT-M-005 Implementation of standardization methods for characterizing and/or performance validation of

nanoparticles

RIA NA TT & NT WGs (Networking;

Communication)

NT ALL NT-L-001 New business strategies and business models for nano-

enabled products

CSA NA TT & NT WGs (Networking;

Communication)NT ALL NT-L-002 Education on Marketing and

Communication Skills in NMP field

CSA NA TT & NT WGs (Skills & Education;

Networking; Communication)

NT VC2, VC3

NT-L-003 Joint EU & MS activity to support EU nano-regulation with focus on

nanoparticles <5nm

CSA NA NT WGs (Regulation; Standardization;

Research; Safety)NT ALL NT-L-004 EU and International Cooperation

for the development of added-value, low cost and eco-friendly nano-related products adopting

"safety by design" approach

CSA NA NT WGs (Safety; Standardization;

Research)

The complete description of Pilot Line 1b technical and non-technical actions can be found in Ap-pendices II and V, and an overall description of Pilot Line 1b can be found in Appendix VI.

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Implementation Roadmap on value chains and related pilot lines 51

Table 5-5 explains Pilot line 1b Business Model developed from VC Experts and stakeholder con-tributions during the Second Value Chain Workshop with a methodology based on canvas models.

Table 5-5: Pilot Line 1b Business Plan

Key

Par

tner

sK

ey A

ctiv

ities

Valu

e Pr

opos

ition

Cus

tom

er R

elat

ions

hip

CustomerSegments

•Nano-materialsproducers

•Bitumenproducers

•Orig

inalequipmentm

anu-

fact

urer

(OE

M)

•ProductR&D

•Production&installation

•Marketinganddurability

•Sales

•Increaseofabrastionresist

-an

ce o

f the

sur

face

s•Increa

seofthemecha

ni-

cal p

rope

rtie

s of

the

bitu

-m

en m

ater

ials

(fat

igue

and

Yo

ung

mod

ulus

)•Reductionofthethickness

of p

avem

ent,

inc

reas

ed

dura

bilit

y an

d de

crea

sed

mai

nten

ance

cos

ts•Durab

ilityofne

wdevel

-op

ed p

avem

ents

wel

l abo

ve

stan

dard

sys

tem

s

•New

sletters

•Promotions

•Robusts

alesservice(tai-

lore

d so

lutio

n)•Robustpost-salesservice

•Highw

ayadm

inistrations

•Airportadm

inistrations

•Cityroadadm

inistrations

Key

reso

urce

sC

hann

els

•Personnel

•Content&agreements

•Patent/producttech

•Tradesecret–microbe

•Researchexpertise

•Uniquebrandpositioning

•Workshopswithadm

inistra

-tio

n•Technicalconferenceswith

publ

ic o

ffice

rs a

nd p

ublic

pr

ivat

e pa

rtner

ship

CostS

tructure

RevenueStreams

•R&D

•Nano-materials

•Salaries

•Utilities

•Individualproductunitssale

•Productmaintenance

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology52

Table 5-6 shows examples of possible consortia structures that were developed around Pilot Line 1b during the Industrial Alliance Workshop. These consortia structures help to evaluate the indus-trialprofitabilityofproductsandservicesproposedtobedeveloped.

Table5-6:PilotLine1b-ExamplesofpossibleConsortiaStructures

VCSTEP PROPOSEDACTIVITY NEEDEDPARTNERHIPS

MATERIAL

Pilot line for low cost metal and metal oxidelowmicron(25μm)submicronand nanoparticlesCoatings for protection of infrastructure (composite and concrete systems)Low friction coating by laser shock peening surface technology (currently TRL4)

Materials technology & development: R&D centres; Spin-off companies; SMEsExpert consultants

Developed powders (300 kg) Powders for: HVOF, cold spraying (TRL 4-6)

Powders experts: SMEs

Improved mechanical properties Raw materials treatment experts

TOOL

Atmospheric plasma technologyTechnology for UV protectionDesign of wear-resistant nanocomposite coatings

Surface coatings technology (e.g., plasma technology, UV protection): Research centres; spin-offs; SMEsExpert consultants

Plasma equipment personnel Plasma treatment expertsProcessqualificationEvaluation of durability of coatings / coated elements

Qualificationcentres

Testing on lab cars Testing centresDissemination & Exploitation Broadcasting experts

ASSEMBLY Integration of technology at real scale (application process)

System integrator

FINAL PRODUCT

Part of pilot linePlants for manufacturing and laboratory

Production facilities (industrial partner)

Surface activation and functionalization of objects with complex geometry (TRL 4-6)

Surface treatment experts: SMEs

Productqualification QualificationcentresandendusersPlastic components with high added value (TRL 5-7)

Specialty plastics manufacturers

Application of nanostructured coatings to automotive turbochargers, gears (in-dustrial and automotive), real testing, end user for cutting tools

Automotive end user demonstrator (auto-motive part validator)

LCA/LCC Life Cycle and Life Cost AnalystsLCA

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Implementation Roadmap on value chains and related pilot lines 53

5.2PilotLine2–Manufacturingoflightweightmultifunctionalmaterialswithnano-enabledcustomisedthermal/electrical

conductivity properties

In the following paragraphs VC4 Pilot Line 2 - Manufacturing of lightweight multifunctional materi-als with nano-enabled customised thermal/electrical conductivity properties technical and non-technicalactionsarebrieflydescribed.Pilotline2businessplansaredescribedtootogetherwiththeexamplesofpossibleconsortiastructuresandaspecificriskanalysis.

Table5-7brieflydescribesPilotLine2technicalandnon-technicalactionsintermsofrelatedVC,ActionTitleandID,ActionType,expectedTRLandresponsibleWorkingGroups.TheflagT/NTinthefirstcolumnofTable5-7detailswhethertheactionistechnicalornon-technical.

Table 5-7: Pilot 2 Actions summary

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

T VC4 VC4-S-001 Scouting of enabling manufac-turing techniques to scale up

innovative productions through theIdentificationofbreakthrough

market models

CSA NA TT

T VC4 VC4-S-002 Development of hybrid LCA/LCC and FE modelling techniques for

smart lightweight composites

RIA 5-6 Res

T VC4 VC4-S-004 Composite or Hybrid Multifunc-tional Materials and Systems

RIA 5-6 Res & Ind

T VC4 VC4-M-001 Integrated European web-based Platform for advanced composite materials processing, characteri-zation and standards (JRC-like)

CSA NA Res; Ind & NT WGs (Networking)

T VC4 VC4-M-002 Innovative manufacturing equipment for advanced nano-

integrated materials (e.g. on-line characterization controls and operational standards compli-

ance evaluation)

RIA 7-8 Ind;

T VC4 VC4-M-003 Advanced techniques for experi-mental assessment of nano-ma-

terials properties

RIA 3-6 Res & NT WGs (Standardization)

T VC4 VC4-M-003 Advanced techniques for experi-mental assessment of nano-ma-

terials properties

RIA 3-6 Res & NT WGs (Standardization)

T VC4 VC4-L-002 Encourage stronger industrial environment of cooperation and culture of funding for develop-

ment of forthcoming technologies

CSA NA Ind; TT; Res & NT WGs (Skills)

NT ALL NT-S-001 Networking, sharing best practices and promoting harmo-

nized methodologies such as standards or other authoritative

guidelines on managing nanoma-terials and related products along

their life cycle

CSA NA NT WGs (Standardiza-tion; Networking; Com-

munication; Regula-tion)

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology54

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

NT ALL NT-S-002 Promotion of effective communi-cationonnano,fromdefinitionofnano to nanolabelling and nano-

relatedrisksandbenefits

CSA NA NT WGs (Communica-tion; Safety; Network-ing; Regulation; Skills

and Education)NT ALL NT-S-003 EU and International Cooperation

for development and promotion of effective, practicable and low cost toxicology testing methods

RIA 7 NT WGs (Safety; Net-working; Standardiza-

tion; Regulation)

NT VC1, VC2, VC3

NT-S-004 Promoting education, training activities and industry-academia exchanges on nanostructured

surfaces and nanocoatings

CSA NA NT WGs (Skills & Education)

NT ALL NT-S-005 Proof of concept of safety risk assessment and management on

pilot line products

RIA 7 NT WGs (Safety; Standardization)

NT ALL NT-M-001 Harmonization and standardiza-tion of protocols and develop-ment of a working agenda for

education and training on real-life scenarios in several sectors

CSA NA NT WGs (Skills & Education; Communi-cation; Networking)

NT ALL NT-M-002 Exploitation and dissemination ofbestpracticesinthefieldofpublic co-funded projects in

nanotechnology

CSA NA NT WGs (Networking; Communication; Skills & Education; Safety)

NT ALL NT-M-003 Cross-sectorial Technology Transfer program in the NMP

field

CSA NA TT & NT WGs (Net-working, Communi-

catioNT ALL NT-M-004 Effective communication and

dialogue with the EU society on the social and economic impact

of nano

CSA NA TT & NT WGs (Com-munication; Network-

ing; Safety)

NT VC2, VC3

NT-M-005 Implementation of standardiza-tion methods for characterizing

and/or performance validation of nanoparticles

RIA NA TT & NT WGs (Net-working; Communica-

tion)

NT ALL NT-L-001 New business strategies and business models for nano-ena-

bled products

CSA NA TT & NT WGs (Net-working; Communica-

tionNT ALL NT-L-002 Education on Marketing and

Communication Skills in NMP field

CSA NA TT & NT WGs (Skills & Education; Network-ing; Communication)

NT VC2, VC3

NT-L-003 Joint EU & MS activity to support EU nano-regulation with focus on

nanoparticles <5nm

CSA NA NT WGs (Regula-tion; Standardization;

Research; Safety)NT ALL NT-L-004 EU and International Cooperation

for the development of added-value, low cost and eco-friendly nano-related products adopting

"safety by design" approach

CSA NA NT WGs (Safety; Standardization; Re-

search)

The complete description of Pilot Line 2 technical and non-technical actions can be found in Ap-pendices IV and V, and an overall description of Pilot Line 2 can be found in Appendix VII.

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Implementation Roadmap on value chains and related pilot lines 55

Table 5-8 explains Pilot line 2 Business Model developed from VC Experts and stakeholder contri-butions during the Second Value Chain Workshop with a methodology based on canvas models.

Table 5-8: Pilot Line 2 Business Plan

Key

Par

tner

sK

ey A

ctiv

ities

Valu

e Pr

opos

ition

Cus

tom

er R

elat

ions

hip

CustomerSegments

•Materialsuppliers

•Softwarean

dau

tomation

prov

ider

s•Measurementinspection

•Certificationauditors

•Consultants

•End-users

•R&D,testingandfinalvali-

datio

n Pr

oduc

tion

and

qual

-ity

ass

essm

ent

•Managem

ent

•Engineering(tooling)

•Requirements

•Adequateassessmentand

man

agem

ent

of r

isks

to

heal

th a

nd e

nviro

nmen

t in-

clud

ing

LCA

•Highe

rpe

rforman

ceand

cost

redu

ctio

n•Functionalityvalidationand

asse

ssm

ent

•Qualitycontrol

•Efficiency:e

nviro

nmental,

reso

urce

, tec

hnic

al

•IPR/contractagreements

•Knowledgeintensive

•Com

plem

entarypartner

-sh

ips

(win

-win

)

•Equipmentm

anufacturers

•Materialproducers

•Productdevelopers

•Sem

i-finishedproducts

Cus

tom

ers

are

dist

ribut

ed

alon

g di

ffere

nt p

ositi

ons

in th

e va

lue

chai

n

Key

reso

urce

sC

hann

els

•Personnel

•Externalkeyknowledge

•Materialandequipment

•Financialresources

•Disseminationviainternet,

mee

tings

, wor

ksho

ps, e

tc.

•Proximity

•Monitoring

CostS

tructure

RevenueStreams

•Personnel

•Equipment/com

ponents

•Resourcesandsubcontractingrequirements

•IPprotectionandlicensingfees

•Marketinganddissem

ination

•Packaginganddistribution

•Licensingagreem

ents

•Consulting

•Knowledge(patents,IPRs,productionrights)

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology56

Table 5-9 shows examples of possible consortia structures that were developed around Pilot Line 2 during the Industrial Alliance Workshop. These consortia structures help to evaluate the industrial profitabilityofproductsandservicesproposedtobedeveloped.

Table5-9:PilotLine2-ExamplesofpossibleConsortiaStructures

VCSTEP PROPOSEDACTIVITY NEEDEDPARTNERHIPS

MATERIAL

CNT manufacturer (SW to MW + functionalization) CNT incorporation (thermoplastics, thermosets, elastomers, masterbatches/ compounds, wafer, solvent) Properties: electrical, mechanical,flameretardant

Centres for nanotechnology and smart materials

Additivethinfilmofmultifunctionalmaterial (oxide) with submicrometrs resolution. (transparent conductive: TRL 4; thermoelectric: TRL1)

Additive manufacturing suppliers

Lightweight anti pollutant and self-healing materials for structural systemsandforedification

Technical material suppliers

Development of bulk nanostructured metalalloysalsoasfibresforcomposites

R&D centres and universities

Multifunctional coatings for corrosion resistanceandfireresistancefrom60to30μm,thick,50%lighter

Surface treatment experts

Electrical conductive composites (thermoset and thermoplastics)

Curing process experts

Powders Powder material with the required properties Production plants powders

Powders experts SMEs

Pilot line for low cost metal low-micron, sub-micron and nano particles

R&D centres and universities

Solid state material/Polymer dispersions TRL 4 -> 6

Material developers

Thermoelectric materials and systems TRL 5-7

collaboration with start-up company and TCR-1 supplier in automotive sector

Insulating materials for electric cables TRL 4-6 (collaboration with industrial partner-ongoing collaboration-)

Materials for thermal insulation textile based too

Anti-scratch applications

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Implementation Roadmap on value chains and related pilot lines 57

VCSTEP PROPOSEDACTIVITY NEEDEDPARTNERHIPS

TOOL

Existing pilot lines for thermoplastic poltrusion, thermoplastic tape comingling, pre-peg manufacture

Regionalclustertofinancedevelopmentor use of pilot manufacturing line as open access

Lab scale high shear mixing and bead milling Process upscaling

Production plants and equipments

Composite testing and analysis Including electrical impedance spectroscopy

Certificationauditors

Thermal/structural calculation Multifunctional modellingUltrasound spray coating technology and large scale equipment

Surface treatment knowhow and facilities

Testing and validation of lab cars Consultancy on equipment development and validation

In line optical inspection Sensoring providersLarge scale, low cost, effective environmental friendly coating technology for a large range of applications: automotive, textile, construction, energy (photovoltaic)

End users as demonstrator of the technologies

Process upscaling Production facilitiesAtmospheric plasma treatment and equipment for increase performances of lightweight materials (composites) duetobetterinteractionfibre-matrixTRL 6-7 Atmospheric plasma treatment and equipment for functionalization of composites surface for multi-functionalities TRL 6-7 Atmospheric plasma treatment and equipment for treatment of complex geometries TRL 5-6Plasmaequipmentfor:fibresurfacefunctionalization, complex geometries composites

Plasma treatment experts and facilities

Well-established dissemination channels (newsletter, training, website, conferences)Exploitation

Broadcasting experts

Proposal writing Strong track record of EU project coordination

EU project experts and coordinators

Core competence (integration of technology into real systems: demonstration, validation of pilot lines/ project concept TRL 6-7)

System integrators

ASSEMBLYProduction of prototypes Experimental production plantsSHM embedded systems on composites

Sensoring providers

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology58

VCSTEP PROPOSEDACTIVITY NEEDEDPARTNERHIPS

FINAL PRODUCT

Product: Brake Pad Automotive end users as product demonstrators

LCA/LCC Life Cycle and Life Cost AnalystsCommercialization of coating equipment and formulation

industrial partners for product validation and exploitation

End user for automotive demonstrator product (bumper trim) validator TRL 5-7

Automotive sector applications

Panels for thermal insulation Building sector applicationsAirbus and aeronautics devices qualifierlabs

Industries in aeronautics sector Aerospace testing (simulated lightning strike)Aero vehicles developers

Production facilities for automotive applications

Plants and equipment providers

Lab cars for real testing and validation CertificationcentresTraining, dissemination and exploitation plan

Public authorities

Silver nanowires TRL 4-6 (-ongoing collaboration-)

Collaboration with nanowires expert SME

Application of lightweight multifunctional materials to vehicle body, automotive parts, bumpers, drive shaft, gear case

Automotive sector applications

Textile industrial partners for product validation and exploitation Pilot line developers need

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Implementation Roadmap on value chains and related pilot lines 59

5.3 PilotLine3–PrintedmicrofluidicMEMSandbiologicalapplications

In the following paragraphs VC1 Pilot Line 3 - Printed microfluidic MEMS and biological applica-tions technical and non-technical actions are described. Pilot line 3 business plan is described too, together with the examples of possible consortia structures estimated by the experts during theIndustrialAllianceWorkshopandaspecificriskanalysis.

5.3.1 PilotLine3a-Nozzles,filters,sensorapplicationsandmulti-usechip

Table5-10brieflydescribesPilotLine3atechnicalandnon-technicalactionsintermsofrelatedVC,ActionTitleandID,ActionType,expectedTRLandresponsibleWorkingGroups.TheflagT/NTinthefirstcolumnofTable5-10detailswhethertheactionistechnicalornon-technical.

Table5-10:PilotLine3aActionsSummary

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

T VC1 VC1-S-001 Demonstrators for non-conventional MEMS (e.g. built

with additive manufacturing techniques) & other mechatronic

devices

RIA 7 Ind & Res

T VC1 VC1-S-003 Development of 3D printing systems (advanced material manufacturing approaches,

additive manufacturing, metrology and smart software)

RIA 5-7 Ind & Res

T VC1 VC1-M-003 Industrial oriented research and demonstration on injection moulding

of polymeric-based products with nanostructured functionalized

surfaces

RIA 7 Ind & Res

T VC1 VC1-L-002 New generation of disruptive injection moulding machines

RIA 7 Ind

NT ALL NT-S-001 Networking, sharing best practices and promoting

harmonized methodologies such as standards or other authoritative guidelines on

managing nanomaterials and related products along their life

cycle

CSA NA NT WGs (Standardization;

Networking; Communication;

Regulation)

NT ALL NT-S-003 EU and International Cooperation for development and promotion of effective, practicable and low cost

toxicology testing methods

RIA 7 NT WGs (Safety; Networking;

Standardization; Regulation)

NT VC1, VC2, VC3

NT-S-004 Promoting education, training activities and industry-academia exchanges on nanostructured

surfaces and nanocoatings

CSA NA NT WGs (Skills & Education)

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology60

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

NT ALL NT-M-001 Harmonization and standardization of protocols and

development of a working agenda for education and training on real-life scenarios in several sectors

CSA NA NT WGs (Skills & Education;

Communication; Networking)

NT VC2, VC3

NT-M-005 Implementation of standardization methods for characterizing and/

or performance validation of nanoparticles

RIA NA TT & NT WGs (Networking;

Communication)

NT ALL NT-L-001 New business strategies and business models for nano-

enabled products

CSA NA TT & NT WGs (Networking;

Communication)NT ALL NT-L-002 Education on Marketing and

Communication Skills in NMP field

CSA NA TT & NT WGs (Skills & Education;

Networking; Communication)

The complete description of Pilot Line 3a technical and non-technical actions can be found in Ap-pendices I and V, and an overall description of Pilot Line 3a can be found in Appendix VIII.

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Implementation Roadmap on value chains and related pilot lines 61

Table 5-11 explains Pilot line 3a Business Model developed from VC Experts and stakeholder con-tributions during the Second Value Chain Workshop with a methodology based on canvas models.

Table 5-11: Pilot Line 3a Business Plan

Key

Par

tner

sK

ey A

ctiv

ities

Valu

e Pr

opos

ition

Cus

tom

er R

elat

ions

hip

CustomerSegments

•Raw

materialproducer

•Equipmentsuppliers

•Systemintegrators

•Researchcenters,univer-

sitie

s or

com

pani

es w

here

R

&D

act

iviti

es a

re o

ut-

sour

ced

•Fu

llscaletestingandpro-

duct

ion

•R&D

•Modellingandsimulations

(CA

D/C

AM

/CIM

impl

emen

-ta

tion)

•Adequateassessmentand

man

agem

ent

of r

isks

to

heal

th a

nd e

nviro

nmen

t in-

clud

ing

LCA

Bio

logi

cal

•Low-costv

ariants:ubiqui-

tous

dia

gnos

tics

and

test

ing

(e.g

. poi

nt o

f car

e di

agno

s-tic

s)•High-throug

hputsystems

for l

abor

ator

ies

Non

-bio

logi

cal:

•Highe

rpe

rforman

cesen

-so

rs,

actu

ator

s an

d flu

id

man

ipul

atio

n du

e to

sca

led-

dow

n di

men

sion

Low-costm

icrofluidicsensors

and

actu

ator

s

•Personalm

onitoring

•ITenabled(cloud)

•Pharmaceuticals

•Medicaldevices(w

earable)

•Healthcareproviders

•ChemicalMicroreactorand

ener

gy•ICT(especiallywirelessand

optic

al n

etw

orks

)

Key

reso

urce

sC

hann

els

•Pe

rsonnel(technicalexper

-tis

e)•IP

•Teststructure

•Manufacturingfacilitiesand

prod

uctio

n lin

es•Advancedmetrologyapps

•Personalcom

munication&

med

ia/in

tern

et•Directsalesto

bigcom

pa-

nies

and

sys

tem

inte

grat

ors

•Worldwidedistributors

CostS

tructure

RevenueStreams

•Personnel

•Materialsupplies

•Facilityandequipm

entcosts

•R&D

•Marketingandsales

•Directsalesofproducts

•Fundedresearchprojectsbybigcom

panies

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology62

Table 5-12 shows examples of possible consortia structures that were developed around Pilot Line 3a during the Industrial Alliance Workshop. These consortia structures help to evaluate the industrialprofitabilityofproductsandservicesproposedtobedeveloped.

Table5-12:PilotLine3a-ExamplesofpossibleConsortiaStructures

VCSTEP PROPOSEDACTIVITY NEEDEDPARTNERHIPS

MATERIAL

Resins Raw materials providersCoatings Material manufacturingNanofluids:inorganicparticlesdispersions NanofluidsprocessexpertsGradient functionalities Nanomaterials process experts

TOOL

Polymer based processes Polymer processes suppliersMultimaterial deposition Raw material processes expertsAnalysis Modelling experts3D microprinter processes Additive manufacturing processMetrology and inspection tool prototype Sensoring providersNew distributed manufacturing model (TRL 5) Modelling expertsDissemination & Exploitation Broadcasting experts

ASSEMBLY

Additive micromanufacturing platform Industry Providing Additive Manufacturing Machines

Platform integration System intergratorsMetrology and inspection tool (custom) Sensoring providers3D microprinter machinery 3D additive manufacturing platform: micronanomanufacturing; gradient material deposition (TRL 4 ->6)

Additive manufacturing equipments

FINAL PRODUCT

LCA Life cycle analysts

Production plantIndustrial Facilities Industries in manufacturing microfluidicchip

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Implementation Roadmap on value chains and related pilot lines 63

5.3.2 Pilotline3b-PrintedmicrofluidicMEMSandbiologicalapplications: Bio-medical/bio-physicalssensors,actuatorsandotherdevices

Table5-13brieflydescribesPilotLine3btechnicalandnon-technicalactionsintermsofrelatedVC,ActionTitleandID,ActionType,expectedTRLandresponsibleWorkingGroups.TheflagT/NTinthefirstcolumnofTable5-13detailswhethertheactionistechnicalornon-technical.

Table5-13:Pilot3bActionsSummary

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

T VC1 VC1-S-001

Demonstrators for non-conventional MEMS (e.g. built

with additive manufacturing techniques) & other mechatronic

devices

RIA 7 Ind & Res

T VC1 VC1-M-002

Enhanced interfaces to improve solid–gas, solid–liquid, and liquid-gas interactions for breakthrough applications

RIA 6 Res

NT ALL NT-S-001

Networking, sharing best practices and promoting

harmonized methodologies such as standards or other authoritative guidelines on

managing nanomaterials and related products along their life

cycle

CSA NA

NT WGs (Standardization;

Networking; Communication;

Regulation)

NT ALL NT-S-002

Promotion of effective communication on nano, fromdefinitionofnanoto

nanolabelling and nano-related risksandbenefits

CSA NA

NT WGs (Communication;

Safety; Networking; Regulation; Skill &

Education)

NT ALL NT-S-003

EU and International Cooperation for development and promotion of effective, practicable and low cost toxicology testing methods

RIA 7

NT WGs (Safety; Networking;

Standardization; Regulation)

NTVC1, VC2, VC3

NT-S-004

Promoting education, training activities and industry-academia exchanges on nanostructured

surfaces and nanocoatings

CSA NA NT WGs (Skills & Education)

NT ALL NT-S-005Proof of concept of safety risk

assessment and management on pilot line products

RIA 7 NT WGs (Safety; Standardization)

NT ALL NT-M-001

Harmonization and standardization of protocols

and development of a working agenda for education and

training on real-life scenarios in several sectors

CSA NA

NT WGs (Skills & Education;

Communication; Networking)

NT ALL NT-M-002

Exploitation and dissemination ofbestpracticesinthefieldofpublic co-funded projects in

nanotechnology

CSA NANT WGs (Networking; Communication; Skills & Education; Safety)

NT ALL NT-M-003Cross-sectorial Technology

Transfer program in the NMP field

CSA NATT & NT WGs (Networking,

Communication)

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology64

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

NT ALL NT-M-004

Effective communication and dialogue with the EU society on the social and economic impact

of nano

CSA NATT & NT WGs

(Communication; Networking; Safety)

NT VC2, VC3 NT-M-005

Implementation of standardization methods for characterizing and/or performance validation of

nanoparticles

RIA NA TT & NT WGs (Networking;

Communication)

NT ALL NT-L-001New business strategies and business models for nano-

enabled productsCSA NA

TT & NT WGs (Networking;

Communication)

NT ALL NT-L-002Education on Marketing and

Communication Skills in NMP field

CSA NA

TT & NT WGs (Skills & Education;

Networking; Communication)

NT VC2, VC3 NT-L-003

Joint EU & MS activity to support EU nano-regulation with focus on

nanoparticles <5nmCSA NA

NT WGs (Regulation; Standardization;

Research; Safety)

NT ALL NT-L-004

EU and International Cooperation for the development of added-

value, low cost and eco-friendly nano-related products adopting

"safety by design" approach

CSA NANT WGs (Safety; Standardization;

Research)

The complete description of Pilot Line 3b technical and non-technical actions can be found in Ap-pendices I and V, and an overall description of Pilot Line 3b can be found in Appendix VIII.

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Implementation Roadmap on value chains and related pilot lines 65

Table 5-14 explains Pilot line 3b - Business Model developed from VC Experts and stakeholder con-tributions during the Second Value Chain Workshop with a methodology based on canvas models.

Table 5-14: Pilot Line 3b Business Plan

Key Activities Value Proposition

• ProductandtechnologyR&D• Production,testingandcharacterisation• Standardisation• Productsadvancedpromotion• Adequateassessmentandmanagementofrisks

to health and environment including LCA

Biological• Low-costvariants:ubiquitousdiagnosticsand

testing (e.g. point of care diagnostics)• High-throughputsystemsforlaboratoriesNon-biological:• Higherperformancesensors,actuatorsandfluid

manipulation due to scaled-down dimensionLow-costmicrofluidicsensorsandactuatorsKey resources

• CIMimplementationandexpertise• Financialresourcesandexpertise

CostStructure

• Personnel• R&D• Rawmaterials• Productionfacilitiesandequipment• Marketingandsales• Standardisation

Table 5-15 shows examples of possible consortia structures that were developed around Pilot Line 3b during the Industrial Alliance Workshop. These consortia structures help to evaluate the industrialprofitabilityofproductsandservicesproposedtobedeveloped.

Table5-15:PilotLine3b-ExamplesofpossibleConsortiaStructures

VCSTEP PROPOSEDACTIVITY NEEDEDPARTNERHIPS

MATERIALEquipment and process material Universities and research centresResins Raw materials providersCoatings Material manufacturing

TOOL

Metrology and inspection technology tool (custom)

Sensoring suppliers

Analysis Experts in clinical diagnostic and hygiene monitoring tests

Technology tool prototype Equipment suppliersProcess to develop adhesive-non adhesive implants TRL 7

Facilities providers

Dissemination & Exploitation Broadcasting expertsASSEMBLY

FINAL PRODUCT

LCA Life cycle Analysis expertsBio-scaffolds of transparent conductive oxide(TCO)reductionbelow1μm(TRL:1 ->4) (grow, differentiate, organize stem cells)

Universities and research centres

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology66

5.4 Pilot Line 4 - Non mainstream Micro-Electro-Mechanical SystemsandArchitectures

In the following paragraphs VC1 Pilot Line 4 - Non mainstream Micro-Electro-Mechanical Systems and Architectures technical and non-technical actions are described. Pilot line 4 business plan isdescribedtoo,togetherwiththeexamplesofpossibleconsortiastructuresandaspecificriskanalysis.

5.4.1 PilotLine4a-NonmainstreamMicro-Electro-MechanicalSystemsandArchitectures:AdvancedCMOScompatibledigitalfabrication

Table5-16brieflydescribesPilotLine4atechnicalandnon-technicalactionsintermsofrelatedVC,ActionTitleandID,ActionType,expectedTRLandresponsibleWorkingGroups.TheflagT/NTinthefirstcolumnofTable5-16detailswhethertheactionistechnicalornon-technical.

Table5-16:PilotLine4aActionsSummary

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

T VC1 VC1-S-001 Demonstrators for non-conventional MEMS (e.g. built

with additive manufacturing techniques) & other mechatronic

devices

RIA 7 Ind & Res

NT ALL NT-S-001 Networking, sharing best practices and promoting

harmonized methodologies such as standards or other authoritative guidelines on

managing nanomaterials and related products along their life

cycle

CSA NA NT WGs (Standardization;

Networking; Communication;

Regulation)

NT ALL NT-S-002 Promotion of effective communication on nano, fromdefinitionofnanoto

nanolabelling and nano-related risksandbenefits

CSA NA NT WGs (Communication;

Safety; Networking; Regulation; Skills &

Education)NT ALL NT-S-003 EU and International Cooperation

for development and promotion of effective, practicable and low cost toxicology testing methods

RIA 7 NT WGs (Safety; Networking;

Standardization; Regulation

NT VC1, VC2, VC3

NT-S-004 Promoting education, training activities and industry-academia exchanges on nanostructured

surfaces and nanocoatings

CSA NA NT WGs (Skills & Education)

NT ALL NT-S-005 Proof of concept of safety risk assessment and management on

pilot line products

RIA 7 NT WGs (Safety; Standardization)

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Implementation Roadmap on value chains and related pilot lines 67

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

NT ALL NT-M-001 Harmonization and standardization of protocols

and development of a working agenda for education and

training on real-life scenarios in several sectors

CSA NA NT WGs (Skills & Education;

Communication; Networking)

NT ALL NT-M-002 Exploitation and dissemination ofbestpracticesinthefieldofpublic co-funded projects in

nanotechnology

CSA NA NT WGs (Networking; Communication; Skills & Education; Safety)

NT ALL NT-M-003 Cross-sectorial Technology Transfer program in the NMP

field

CSA NA TT & NT WGs (Networking,

Communication)NT ALL NT-M-004 Effective communication and

dialogue with the EU society on the social and economic impact

of nano

CSA NA TT & NT WGs (Communication

Networking; Safety)

NT VC2, VC3

NT-M-005 Implementation of standardization methods for characterizing and/or performance validation of

nanoparticles

RIA NA TT & NT WGs (Networking;

Communication)

NT ALL NT-L-001 New business strategies and business models for nano-

enabled products

CSA NA TT & NT WGs (Networking;

Communication)NT ALL NT-L-002 Education on Marketing and

Communication Skills in NMP field

CSA NA TT & NT WGs (Education; Networking;

Communication)NT VC2,

VC3NT-L-003 Joint EU & MS activity to support

EU nano-regulation with focus on nanoparticles <5nm

CSA NA NT WGs (Regulation; Standardization;

Research; Safety)NT ALL NT-L-004 EU and International Cooperation

for the development of added-value, low cost and eco-friendly nano-related products adopting

"safety by design" approach

CSA NA NT WGs (Safety; Standardization;

Research)

The complete description of Pilot Line 4a technical and non-technical actions can be found in Ap-pendices I and V, and an overall description of Pilot Line 4a can be found in Appendix IX.

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology68

Table 5-17 explains Pilot line 4a Business Model developed from VC Experts and stakeholder con-tributions during the Second Value Chain Workshop with a methodology based on canvas models.

Table 5-17: Pilot Line 4a Business Plan

Key

Par

tner

sK

ey A

ctiv

ities

Valu

e Pr

opos

ition

Cus

tom

er R

elat

ions

hip

CustomerSegments

•Largescaleintegrators

•Equ

ipmen

tan

dde

vice

sm

anuf

actu

rer

•Upstream

industries

•Smartm

aterialdevelopers

•SMEs(com

pone

ntsan

dpi

lot l

ine

equi

pmen

t man

u-fa

ctur

er)

•PlatformRTO

scoveringthe

valu

e ch

ain

•R&D

institutesanduniversi

-tie

s

•Developingdigitalfabrica-

tion

tech

niqu

es c

ompa

tible

withinCMOSflow

orontop

of C

MO

S d

evic

es•Testing:performances,reli-

abili

ty, r

obus

tnes

s•Produ

ctionofm

icro-nan

opatternedth

infilmsforn

a-no

devi

ces

•Adequateassessmentand

man

agem

ent

of r

isks

to

heal

th a

nd e

nviro

nmen

t in-

clud

ing

LCA

•Rem

ovepo

llutionassoci

-at

ed w

ith s

tand

ard

litho

gra-

phy

•Pollutionreductionbymak

-in

g ke

y st

ep a

ddiv

ite•Multifunctionality

•Rem

oveetchingprocess

(difficultetchmaterial)

•Masklessfabricationfor

R&

D,

ram

pup

and

smal

l vo

lum

es

•Dire

ctaccesstothe

pilot

line

•Organ

izationofspe

cific

pilo

t lin

e cr

oss

Eur

ope

pro-

vidi

ng c

ompl

emen

ting

ser-

vice

s an

d co

mpl

ete

line

of

prod

uctio

n

•Healthyindustries

•Buildingindustries

•Endconsumerselectro

nic

OE

M (

Sam

sung

, P

hilip

s,

Son

y)•Autom

otive

•Textileindustry

•Telecomdevelopers

•Hum

ansensorsandro

bot-

ics

•Integrated

systemsstart-

ups

•Energyharvesting

Key

reso

urce

sC

hann

els

•Metho

dology

forlinking

co

mpo

nent

s an

d su

b-co

m-

pone

nts

•Printedelectro

nicprocess

linewithhighflexibilityand

diffe

rent

blo

cks

to d

evel

op

specificsteps

•Developmento

fnew

tools

for c

ompa

tibili

ty o

f ass

em-

bles

and

int

erco

nnec

tion

proc

ess

•Materialexpertiseandfor-

mul

atio

n

•Som

eofthe

traditio

nal

sem

icon

duct

or d

istri

butio

n ch

anne

ls a

nd m

arke

t seg

-m

ents

•Investmentandtradeshow

CostS

tructure

RevenueStreams

•Equipment

•R&D

•IPmanagem

ent

•Disseminationandtraining

•ServicerevenuefromPilotLine

•Royalties

•Advisoryonbuildingoflargescaleprocessingequipment

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Implementation Roadmap on value chains and related pilot lines 69

Table 5-18 shows examples of possible consortia structures that were developed around Pilot Line 4a during the Industrial Alliance Workshop. These consortia structures help to evaluate the industrialprofitabilityofproductsandservicesproposedtobedeveloped.

Table5-18:PilotLine4a-ExamplesofpossibleConsortiaStructures

VCSTEP PROPOSEDACTIVITY NEEDEDPARTNERHIPS

MATERIAL

Resins Raw materials providersCoatings Material manufacturing

Energy harvesting MEMS supplierIntermetallic components (e. g. PZT) to be developed Piezo materials supplier

Nano oxides (e. g. LiNbO3 at TRL 3 ->4) for MOEMS Universities and research centres

TOOL

Equipment and process development for materials

Universities and research centres

Metrology and inspection technology Sensoring suppliersAFM characterization Equipment suppliersMedia outreach, spillover Broadcasting expertsAdditivethinfilmstechnology(equipmentand process) of multifunctional materials (reductionbelow1μm)

Material manufacturing experts

Dissemination & Exploitation Broadcasting experts3D printing process development Additive technology experts

ASSEMBLYSuitable optical AFM inspection and me-trology working prototype

Testing and sensoring providers

3D printer with highest resolution Additive manufacturing equipment

FINAL PRODUCT

LCA Life cycle AnalystsEnd user it - microelectronicsIndustries in semiconductors sectorIndustries in it – electronics systemsIndustries providing electrical, mechani-cal, thermal components

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology70

5.4.2 PilotLine4b-NonmainstreamMicro-Electro-MechanicalSystemsandArchitectures:CheapflexiblehybridorfullpolymerMEMSeco-systems

Table 5-19 describes Pilot Line 4b technical and non-technical actions in terms of related VC, Ac-tionTitleandID,ActionType,expectedTRLandresponsibleWorkingGroups.TheflagT/NTinthefirstcolumnofTable5-20detailswhethertheactionistechnicalornon-technical.

Table5-19:PilotLine4bActionsSummary

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

T VC1 VC1-S-001 Demonstrators for non conventional MEMS (e.g. built

with additive manufacturing techniques) & other mechatronic

devices

RIA 7 Ind & Res

T VC1 VC1-L-001 Breakthrough Hybrid smart materials & systems

RIA 6-7 Res

NT ALL NT-S-001 Networking, sharing best practices and promoting

harmonized methodologies such as standards or other authoritative guidelines on

managing nanomaterials and related products along their life

cycle

CSA NA NT WGs (Standardization;

Networking; Communication;

Regulation)

NT ALL NT-S-002 Promotion of effective communication on nano, fromdefinitionofnanoto

nanolabelling and nano-related risksandbenefits

CSA NA NT WGs (Communication;

Safety; Networking; Regulation; Skills &

Education)NT ALL NT-S-003 EU and International Cooperation

for development and promotion of effective, practicable and low cost toxicology testing methods

RIA 7 NT WGs (Safety; Networking;

Standardization; Regulation)

NT VC1, VC2, VC3

NT-S-004 Promoting education, training activities and industry-academia exchanges on nanostructured

surfaces and nanocoatings

CSA NA NT WGs (Skills & Education)

NT ALL NT-S-005 Proof of concept of safety risk assessment and management on

pilot line products

RIA 7 NT WGs (Safety; Standardization)

NT ALL NT-M-001 Harmonization and standardization of protocols

and development of a working agenda for education and

training on real-life scenarios in several sectors

CSA NA NT WGs (Skills & Education;

Communication; Networking)

NT ALL NT-M-002 Exploitation and dissemination ofbestpracticesinthefieldofpublic co-funded projects in

nanotechnology

CSA NA NT WGs (Networking; Communication; Skills & Education; Safety)

NT VC2, VC3

NT-M-005 Implementation of standardization methods for characterizing and/or performance validation of

nanoparticles

RIA NA TT & NT WGs (Networking;

Communication)

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Implementation Roadmap on value chains and related pilot lines 71

T/NT Value Chain Action ID Action Title Type TRL

Expected Responsible WG

NT ALL NT-L-001 New business strategies and business models for nano-

enabled products

CSA NA TT & NT WGs (Networking;

Communication)NT ALL NT-L-002 Education on Marketing and

Communication Skills in NMP field

CSA NA TT & NT WGs (Skills & Education;

Networking; Communication)

NT ALL NT-L-004 EU and International Cooperation for the development of added-

value, low cost and eco-friendly nano-related products adopting

"safety by design" approach

CSA NA NT WGs (Safety; Standardization;

Research)

The complete description of Pilot Line 4b technical and non-technical actions can be found in Ap-pendices I and V, and an overall description of Pilot Line 4b can be found in Appendix IX.

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology72

Table 5-20 explains Pilot line 4b Business Model developed from VC Experts and stakeholder con-tributions during the Second Value Chain Workshop with a methodology based on canvas models.

Table 5-20: Pilot Line 4b Business Plan

Key

Par

tner

sK

ey A

ctiv

ities

Valu

e Pr

opos

ition

Cus

tom

er R

elat

ions

hip

CustomerSegments

•Largescaleintegrators

•Equ

ipmen

tan

dde

vice

sm

anuf

actu

rers

•IPmanagem

entcom

panies

•Upstream

industries

•SMEs(com

pone

ntsan

dpi

lot l

ine

equi

pmen

t man

u-fa

ctur

er)

•PlatformRTO

scoveringthe

valu

e ch

ain

•MEMSdesignIP

•New

interconnectionmateri-

als,

ass

embl

ing,

wel

ding

for

hybr

id s

yste

ms

•Quality

•New

productsnotavailable

with

3D

prin

ting

•Adequateassessmentand

man

agem

ent

of r

isks

to

heal

th a

nd e

nviro

nmen

t in-

clud

ing

LCA

•New

architectures

•Flexibility

•Transparency

•Lowcost/highvolume

•Lo

win

vestmen

t,disposa-

ble/recyclability/HSE

profile

•Easyfunctionality

•Com

patibilityinliquidgases

devi

ces,

mai

nly

sens

ors

•Com

patib

ilityw

ithother

tech

nolo

gies

•Integrableonconventional

pre-

inst

alle

d pr

oces

ses

•Largescaleproductionca

-pa

bilit

ies

(join

t ven

ture

)•RTD

problem

issuessolving

•Organ

izationofspe

cific

pilo

t lin

e cr

oss

Eur

ope

pro-

vidi

ng c

ompl

emen

ting

ser-

vice

s an

d co

mpl

ete

line

of

prod

uctio

n

•Healtyindustries

•Buildingindustries

•Endconsumerselectro

nic

OE

M (

Sam

sung

, P

hilip

s,

Son

y)•Autom

otive

•Textileindustry

•Telecomdevelopers

•Hum

ansensorsandro

bot-

ics

•Integrated

systemsstart-

ups

•Energyharvesting

Key

reso

urce

sC

hann

els

•Ve

nturecapital(pu

blicor

priv

ate)

for h

ighe

r TR

L•Designofdrivingelectronic

for n

on-c

onve

ntio

nal M

EMS

•Materialexpertiseandfor-

mul

atio

n•Marketing

•Dem

onstrationandproto-

type

bas

ed o

n B

2B•Som

eofthe

traditio

nal

sem

icon

duct

or d

istri

butio

n ch

anne

ls a

nd m

arke

t seg

-m

ents

CostS

tructure

RevenueStreams

•IPmanagem

ent

•InfrastructureandHR

•R&D

•Disseminationandtraining

•ServicerevenuefromPilotLine

•Royalties

•ExploitationofIP

•Advisoryondevelopmentoflargescaleproduction

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Implementation Roadmap on value chains and related pilot lines 73

Table 5-21 shows examples of possible consortia structures that were developed around Pilot Line 4b during the Industrial Alliance Workshop. These consortia structures help to evaluate the industrialprofitabilityofproductsandservicesproposedtobedeveloped.

Table5-21:PilotLine4b-ExamplesofpossibleConsortiaStructures

VCSTEP PROPOSEDACTIVITY NEEDEDPARTNERHIPS

MATERIAL

Resins Raw materials providersCoatings Material manufacturingNano polymers Raw materials providersMetal particles for advanced ink pro-duction Additive manufacturing materials providers

MEMS based on piezo polymers, print-edonflexiblesubstrates Smart material developers

TOOL

Atmosphericplasmaequipmentforflex-ible substrates

High energy manufacturing providers

Metrology and inspection tool (custom)Metrology know-how Sensoring experts3D microprinting processes Additive manufacturing toolsPolymer engineering: alloying, blend-ing,dispersionsnanofluidsTRL3-5

Polymer manufacturing experts

Activationandfunctionalizationofflexi-blesubstances(includingfluorocarbonbased materials) for printing of elec-tronics TRL 6-8

Raw materials manufacturer

Atmospheric plasma technology High energy manufacturing equipmentsDissemination & Exploitation Broadcasting expertsOngoing collaboration with industrial partners

Enterprises contributions

ASSEMBLY

Integration of printed electronics on components for structural health mon-itoring

Large scale integrators

3D microprinting machinery Additive manufacturing equipment and de-vices

FINAL PRODUCT

LCA Life cycle expertsPlants for production Facilities suppliersTechnological platform (300x400 cm2) TRL 4-7

Providers of facilities

Industries in IT – electronics systemsIndustries providing optical components

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology74

5.5PilotLinesriskanalysis

5.5.1 Introduction

In general nanomaterials’ risks to human health or the environment may be considered as a result of the likelihood and amount of nanomaterials release into the environment or exposure of an individual and the toxicity of the materials which are released. The potential release will depend primarily on the type of product and the scenario of use whereas toxicity is more related to the material itself (although this too can depend on how this is incorporated into the product and how it is released). Both aspects must be considered to understand risk. For some products and ap-plications, release is intentional and is a necessary element of product performance. In other ap-plications release marks a loss of the active ingredient and a degradation of product performance. Intensive research over the last 10 years has led to greater understanding of some exposure scenarios and some materials toxicity although many gaps remain. Some of the main risks are summarised in the table below.

Table5-22:Overviewofthepotentialrisksofnanomaterials

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Implementation Roadmap on value chains and related pilot lines 75

A full understanding of the risks also requires information regarding the toxicity of the materials or, morespecifically,thetoxicityofthereleasedmaterials.

Greater risks apply in these products and applications where both the release potential is high and the toxic potential is high. Risks are low in applications where both the potential release and toxicity are low. In general, the better the information that is available, the better the estimate and prioritization of risk. In many cases there is limited information regarding both of these aspects. One approach which can help to prioritise is that of risk banding in which both release and hazard band information are reported in a matrix as illustrated below.

Figure5-2ExampleofRiskMatrix(exposurevshazard)

There are a number of schemes which use this approach including one recently published by ISO (ISO 12901-2, 2014). Such schemes should be used with caution, in particular where information is limited, however they do nevertheless provide a basis for prioritisation. Also important is the concept of tiered risk assessment which is an iterative approach to consisting of usually three phaseswherethelevelofrefinementanddetailoftheinformationrequiredforariskevaluationare proportional to the potential risks based on the consideration of both hazards and exposures together, rather than in isolation.

The potential for release differs at different points in the value chain. In all manufacturing processes, thereisthepotentialforreleaseduringsupply,assembly,finishingpackagingandmaintenanceunless proper assessment and control of these release is carried out. Good guidance, frameworks and methods for the assessment and control of nanoparticle release are available but these must be applied proactively and intelligently and their effectiveness should be assessed.

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology76

5.5.2 Pilotline1riskanalysis

Forproducts,thepotentialforreleaseisspecifictotheproductandhowitistobeused.Hencewithin Pilot Line 1, the different groups of products present different potentials for release. The various products may be grouped as follows according to their release potential.

Groups of products and scenarios where release is intentional: • Applicationofantimicrobialpowdercoatings • Sprayapplicationofantimicrobialpaints • Surfaces(engineered,material,clothing)coatedwithantimicrobialpowderorantimicrobial

paints where release is a necessary element of performance

Groups of products and scenarios where release is possible: • Surfaces(engineered,material,clothing)coatedwithantimicrobialpowderorantimicrobial

paints where the coating is not strongly bound and is released over time due to surface breakup or erosion

• Applicationsinhighwearscenarios,possiblereleaseintotheairorfluids

Groups of products and scenarios where release is unlikely: • Abrasion,wearandcorrosionresistantnano-coatingswhicharefullyeffective • Aerospaceapplications

InformationregardingthespecificmaterialsinPilot line 1 - Nanostructured surfaces and nanocoat-ings is limited and it is likely that they will include materials with both high and low toxicity. The high-est risk will be in those applications where release is intentional and there is a high toxic potential.

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Implementation Roadmap on value chains and related pilot lines 77

5.5.3 Pilotline2riskanalysis

Forproducts,thepotentialforreleaseisspecifictotheproductandhowitistobeused.Hencewithin Pilot Line 2, the different groups of products present different potentials for release and thereforedifferentrisks.TheidentifiedproductsareMaterialswithcustomizedthermal/electricalconductivity properties (e.g. skins of aircrafts for lighting protection, thermal layer, etc.).The various products may be grouped as follows according to their release potential.

Groups of products and scenarios where release is intentional: • Therearenoidentifiedproductswhereintentionalreleaseisforeseen;

Groups of products and scenarios where release is possible: • Any powder forms of products or where dispersion of products in anticipated; • Applicationsinhighwearscenarios,possiblereleaseintotheairorfluids;

Groups of products and scenarios where release is unlikely: • Surfaces where there is no abrasion, wear and corrosion resistant nano-coatings which are

fully effective; • Aerospace (airframe) applications.

On the limited information available, it seems probable that most of the products will fall into the category – “Groups of products and scenarios where release is unlikely” and so risks will typically be lower in this category. However, all product types should be considered. Information regarding thespecificmaterialsinpilotline2islimitedanditislikelythattheywillincludematerialswithboth high and low toxicity.

UseofCNTisspecificallymentionedinthispilotline.Thisisonematerialwheregreatcaremustbe taken to prevent release and exposure due to frequent published reports of its toxicity.

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology78

5.5.4 SpecificrisksforPilotline3

Forproducts,thepotentialforreleaseisspecifictotheproductandhowitistobeused.Hencewithin Pilot Line 3, the different groups of products present different potentials for release and thereforedifferentrisks.TheidentifiedproductsareP1-27,P1-28P1-29andP1-15:3DprintedPolymericmicrofluidicMEMSfornozzlesorfilters,forsensorapplicationsandformulti-usechip(including also injection molded nanostructures in plastics) and P1-11: Lab on chip (including bio-compatibleortoxicscaffolds,activeinfluenceofcellgrowth&differentiation).

The various products may be grouped as follows according to their release potential.

Groups of products and scenarios where release is intentional: • bio-compatible or toxic scaffolds where nano-products are deliberately introduced into the

human body constitute plausible high exposure scenarios; • Sensor applications where the sensors are deliberately released into the environment also

fall into this category.

Groups of products and scenarios where release is possible: • Applications in high wear scenarios, where sensors are shed or wear off.

Groups of products and scenarios where release is unlikely: • PrintedPolymericmicrofluidicMEMSfornozzlesorfilters,forsensorapplicationsandfor

multi-use chip (including also injection molded nanostructures in plastics) and P1-11: Lab on chip.

On the very information available, it seems probable that most of the products will fall into the category – “Groups of products and scenarios where release is unlikely” and so risks will typically be lower in this category. However, bio-compatible or toxic scaffolds where nano-products are deliberately introduced into the human body constitute plausible high exposure scenarios and presentspecificrisks.Thesameistrueforsensorapplicationswherethesensorsaredeliberatelyreleased into the environment. For these product groups in particular, information of actual releases (doses)aswellasthespecifictoxicityisrequiredforeffectiveriskassessment.

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Implementation Roadmap on value chains and related pilot lines 79

5.5.5 Pilotline4riskanalysis

Forproducts,thepotentialforreleaseisspecifictotheproductandhowitistobeused.Hencewithin Pilot Line 4, the different groups of products present different potentials for release and thereforedifferentrisks.TheidentifiedproductsareP1-5:Microelectromechanicalsystems-MEMS(including Micro or Nano Opto-Electro-Mechanical Systems) and P1-31: Non mainstream MEMS.

The various produces may be grouped as follows according to their release potential.

Groups of products and scenarios where release is intentional: • MEMS which are deliberately introduced in to the human body or into the environment

constitute plausible high exposure scenarios; • Sensor applications where the sensors are deliberately released into the environment also

fall into this category.

Groups of products and scenarios where release is possible: • Applications in high wear scenarios.

Groups of products and scenarios where release is unlikely: • Microelectromechanical systems - MEMS (including Micro or Nano Opto-Electro-Mechanical

Systems) and P1-31: Non mainstream MEMS.

On the limited information available, it seems probable that most of the products will fall into the category – “Groups of products and scenarios where release is unlikely” and so risks will typically be lower in this category. However, where nano-products are deliberately introduced into the hu-manbodyconstitutesplausiblehighexposurescenariosandpresentspecificrisk.Thesameistrue for sensor applications where the sensors are deliberately released into the environment. For theseproductgroupsinparticular,informationofactualreleases(doses)andwellasthespecifictoxicity is required for effective risk assessment.

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology

Implementation Roadmap on value chains and related pilot linesAppendices

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6 Appendix I

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Implementation Roadmap on value chains and related pilot lines 83

6 Appendix I

AppendixI-VC1 - Nano and micro printing for industrial manufacturing Actions Description Fiches

ThisappendixcontainsoneactionficheforeachVC1action,whichincludes,whenapplicable,ac-tioncode,title,timeline,productclassesandgaps,specificchallenges(i.e.theneedfortheaction),scope (i.e. the list of objectives), TRL expected, needed economical resources (i.e. the suggested economic size of the projects), impact (i.e. the expected social and economic outcome) and type ofaction.IftheactionhassynergieswithtopicsidentifiedintheNANOfutures Integrated Research and Industrial Roadmap for European Nanotechnology (available at http://www.nanofutures.eu/documents), reference to the Nf topic codes is presented.

Code Title of the actionVC1-S-001 DemonstratorsfornonconventionalMEMS(e.g.builtwithadditive

manufacturing techniques) & other mechatronic devicesTimeline 2015-2018Product Classes IdentifiedGapsP1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Nopilotlineavailable/Moneyforpilotlines• Multifunctionalmaterialintegration• Replaceprintedcircuitboard(PCB)->disruptive(barriertoentry)

P1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Multifunctionalmaterialintegration• Nopilotlineavailable/Moneyforpilotlines• Howtocheckperformance• Advancednon-traditionaloftensmallvolume

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters

• Multifunctionalmaterialintegration• Nopilotlineavailable/Moneyforpilotlines• Characterizationtoolsneeded• Advancednon-traditionaloftensmallvolume

P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Multifunctionalmaterialintegration• Nopilotlineavailable/Moneyforpilotlines• Howtocheckperformance• Insomecasesnanoproductsarenotdevelopedtobescalablein

production and again new innovation is necessaryP1-29: 3D printed Polymeric MEMSformulti-useon-chip

• Multifunctionalmaterialintegration• Nopilotlineavailable/Moneyforpilotlines• Insomecasesnanoproductsarenotdevelopedtobescalablein

production and again new innovation is necessary• Advancednon-traditionaloftensmallvolume

P1-31:NonmainstreamMEMS • Advancednon-traditionaloftensmallvolume• Availability(use&price)ofspecializedmachinery• Howtocheckperformance• Insomecasesnanoproductsarenotdevelopedtobescalablein

production and again new innovation is necessary

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology84

SpecificChallenge• Developingnon-conventionalMEMSandsimilardevicesthatactuallyprovidebreakthroughsolutions

for different sectors, helping to solve the social and economic challenges of our time. · Examples of applicable sectors: pharmaceuticals, ICT, transportation, buildings etc., technologies for

air soil and water management · Mayincludealsomicrofluidicsystems,actuators,sensorsetc.• Oneofthecurrentproblemsistosupportsmallproductionofhighaddedvalueproducts,possiblyup-

grading research labs. • SpecificexamplesofchallengingMEMSandMEMSproductionstechniques: · Hybrid systems; · Combination of integrated smart sensor / actuator systems with other MEM systems · Printed MEMS based on Ferroelectric Polymer Process: - Specificstepneededtopolethematerials - Lackofknowledgeandavailablematerialintheproductionprintingfirms · Printed lines with high aspect ratio · Demo of negative angles · Sub-picoliter jetting and deposition · Control the interaction fo all kind of functional liquids with: A. the Si based materials of deposition

devices. B. the substrates to be printed on.ScopeProjects should aim at:• DevelopingfacilitiesanddemonstratorsfornonmainstreamMEMSinkeyEUsectors.• DevelopandtestdemonstratorsofnonmainstreamMEMSwithhighsocialimpact.• Creatinganetworkofspecializedlabswhichmayofferawidevarietyoftechnologiesataffordablecosts.• CanaimatavarietyofpossiblenovelMEMSapplicationsandfabricationmethods.Examples:• CouldmakeprintedMEMSbasedonferroelectricmaterials.Pointsofattention: - Specificformulationofinks - Polymer pool facilities for high quality in electronics• Usenewmaterials.Examples: - Lead free - Polymers - Monocrystallize PZT - UseofPLDthinfilmspiezodeposition - LeadfreepiezolayerwithPZTcomparableperfomance-->specificchallenge• Newproductiontechniques(e.g.additiveinsteadofsubtractivemanufacturing)• Mostimportanttodefineproductsfordemonstatrotorswiththefollowingattributes - Made on almost industrial scale but below industrial volumes. - Demonstrate non-conventional aspects i.e. be new enough - Focussedonaspecificapplication,buthavewholevaluechaininplace - Should have advantage over traditional competitor to justify investment - Requires moderate investment into equipment - Optional:novelmaterials,inclusionofthinfilmpiezoinwaferscaleSi-basedtechnologiesTarget TRL 7Needed economical resources (public and private)• 4-10M€perproject• Hybridsystems:100–200M€ExpectedImpact• EnablingmanufacturingactivitiesbySMEstoentermarketswithinnovationsthatwerenotpossible

before.• EnablingEuropetocompetewithhighaddedvalueproductssuchMEMSandmechatronicdevices;• Contributingtobridgethecurrentgapbetweenadvancedlabresearchandmarket.SuggestionsonTypeofAction RIA

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Implementation Roadmap on value chains and related pilot lines 85

Code Title of the actionVC1-S-002 Developmentandupscaleoftechnologiesforlowcostlithography

fordeepsubmicronapplications(<20nm)enablingbreakthroughapplications in optics and opto-electronics

Timeline 2015-2018Product Classes IdentifiedGapsP1-2:IntegratedCircuits;SolidStateMemoryDevices

• BlockCopolymersforGuidedSelf-Assembly.• Materialspurity/qualityimprovewithtools• HighpowersourcesforExtremeultravioletlithography(EUV)

P1-3: Printed organic electron-ics

• Lowcostlithoforlargeareas• Roll-to-rollprintingwith<10umresolution

P1-4: Anti-counterfeiting tags • Lowcostlowresolutionprintingforsmallcircuits• Resolutionintheorderofmicron

P1-8: Personalized electronics • Characterizationtoolsneeded• Howtocheckperformance• Toolsforinspection,failureanalysisandtestingof3-Dintegrated

devices• Metrologyfordeepsubmicron

P1-13: 3D printed Polymeric micro-opticslikelensesorpyr-amids

• Developmentofself-assemblytechniques(e.g.blockcopolymers)

P1-22: Optical photonics inte-gratedonSi

• Theproductmightworkbuthastobeassembledandintegrated.This is a gap because this has to be done often by another party

• Multifunctionalmaterialintegration• Replaceprintedcircuitboard(PCB)-->disruptive(barriertoentry)• Advancednon-traditionaloftensmallvolume

P1-25: Plasmonic devices • Characterizationtoolsneeded• Howtocheckperformance• Toolsforinspection,failureanalysisandtestingof3-Dintegrated

devicesP1-30:CMOS-fabforbiddenma-terials

• FlexiblePilotLines

SpecificChallenge• Lackoflowcostlithographyhindersevolutionofthemarket: · Standard Microelectronics (below 20 nm) · Largeareaflexibleelectronics(below1µm) · Requires industrial research · Requires investigation of breakthrough concepts. • Needtodevelopnewinterconnecttechnologiesthatcanactuallymakeuseof(low-cost)sub-micron

level devices · Especiallychallengingforthickfilm(<30um)interconnectScopeProjects should aim at:• Developing(alternative)lithotechnologiesfordeepsubmicron.Examples: · Block copolymers · Extreme Ultra Violet sources · Extreme Ultra Violet materials · Nano imprint• Make(deep)submicronlithorealisticallyavailableforawiderrangeofapplications · Developingalternativeforsub-micronlithographyadaptedforlargeareaflexiblesubstrate(more

reliable and reproducible large area components) · Lower the cost of deep submicron litho · Testing such developed technologies in promising applications: - Optics - Opto-electronics - Flexible electronics - Etc.

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Target TRL 5-6Needed economical resources (public and private)30 – 50 M€Alternative resource estimate: 150 – 300 M€ExpectedImpact• Increasethemarketimpactofnanoprintinginthenanoelectronicsandopticsectorsandflexibleorplastic

electronics• Progressinindustrialresearchonbreakthroughapplications• AnincreaseintheintegrationbetweenNMPandICTrelatedsolutions.• ImprovementsinthetechnologicalbaseandthecompetitivenessofEuropeanindustry · Especiallyforinnovationfieldswhichshowhigheconomicpotentialfortheuseofmicroandnano-

technologies. SuggestionsonTypeofAction RIA

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Implementation Roadmap on value chains and related pilot lines 87

Code Title of the actionVC1-S-003 Development of 3D printing systems (advanced material manu-

facturingapproachesadditivemanufacturing,metrologyandsmartsoftware)

Timeline 2015-2018Product Classes IdentifiedGapsP1-4: Anti-counterfeiting tags •PrintingofantennasonplasticsupportP1-12: 3D printed Nanostruc-turesplasticsassmartsurfaces,e.g.,lotuseffects

• Howtocheckperformance• Toolsforinspection,failureanalysisandtestingof3Dintegrated

devices• Characterizationtoolsneeded.Multifunctionalmaterialintegration.

Investigatespecificationsfornanomaterialsutilizedineach3D-Printing application.

• Metrologytoprove&predictmeantimebetweenfailures.Forspe-cificapplicationneedtodevelopnewtools

• Characterizationtoolsneeded.Investigatespecificationsfornano-materials utilized in each 3D Printing application

P1-13: 3D printed Polymeric micro-opticslikelensesorpyra-mids

• Metrology-->findsmallfibres/reliablepackagingwithoutlasers• Handling2packagingwithoutdamage• Assembly• Multifunctionalmaterialintegration• Multifunctionalmaterialintegration.Investigatespecificationsfor

nanomaterials utilized in each 3D Printing application.P1-14: 3D printed Hybrid optics for LED and lightning

• Characterizationtoolsneeded.Specificationsfornanomaterialsutilized in each 3D Printing application.

• Toolsforinspection,failureanalysisandtestingof3-Dintegrateddevices

• Insomecasesnanoproductsarenotdevelopedtobescalableinproduction and again new innovation is necessary

• Packagingandhandling• Characterizationtoolsneeded.Investigatespecificationsfornano-

materials utilized in each 3D Printing applicationP1-23:3DprintedPhotonicwire-bonds for multi-chip optical connection

• Howtocheckperformance• Nopilotlineavailable/Moneyforpilotlines• Toolsforinspection,failureanalysisandtestingof3Dintegrated

devices• Characterizationtoolsneeded,Investigatespecificationsfornano-

materials utilized in each 3D Printing applicationP1-24: 3D printed microparts for on-chip free-space optical coupling

• Multifunctionalmaterialintegration.Investigatespecificationsfornanomaterials utilized in each 3D printing application.

• Advancednon-traditionaloftensmallvolume• Howtocheckperformance• Packagingandhandling

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters

• Packagingandhandling• Howtocheckperformance• Metrologytoprove&predictmeantimebetweenfailures.Forspe-

cificapplicationneedtodevelopnewtools• Characterizationtoolsneeded.Investigatespecificationsfornano-

materials utilized in each 3D Printing applicationP1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Packagingandhandling• Metrology-->findsmallfibres/reliablepackagingwithoutlasers• Metrologytoprove&predictmeantimebetweenfailures.Forspe-

cificapplicationneedtodevelopnewtools• Characterizationtoolsneeded.Investigatespecificationsfornano-

materials utilized in each 3D Printing applicationP1-29: 3D printed Polymeric MEMSformulti-useon-chip

• Characterizationtoolsneeded• Multifunctionalmaterialintegration• Howtocheckperformance• Toolsforinspection,failureanalysisandtestingof3Dintegrated

devices• Multifunctionalmaterialintegration.Investigatespecificationsfor

nanomaterials utilized in each 3D Printing application

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SpecificChallenge3D printing or additive manufacturing has a huge potential in many sectors (e.g. transportation, medicine and health, mobile industry etc.). However, in order to obtain marketable 3D printed products the following challenges must be overcome:• Making3Dprintingsystemsabletointegrateadvancedmaterialmanufacturingapproaches• Functionalizingexisting3Dobjectsurfacesbyprintingsmethods,metrologyandsmartsoftware.• Makingcurrentoff-linemetrologysystemsandmethodssuitableforon-linemeasurement · Fast online measurement tools for inspection will help to improve the process of 3D nano-manufac-

turing• Convergenanotechnologiesand3Dprintingforinnovative3Dsmartcomponents: · Material reinforcement · Surface functionalization · Surface structuration · Smart parts · Materials for laser polymerisation by SLA and TPP• Developmentofprocessesandmaterialsforfabrication: · Without requirements for supporting structures · Withsimplifieddataprocessing · WithcontinousworkflowScopeThe aim of the projects should be:• Toadvancethestate-of-theartof3Dprintingsystemsandprintingon3Dsurfaces · Integrate manufacturing technology with smart software · Integrate manufacturing technology with fast and reliable metrology systems · Integrate nano and micro fabrication in one processing chain · Develop high performance reliable and reproducible 3D material (polymer, metals, ceramics, UV

sensitive materials...) - Smart, smooth, accurate dimension and features - High-performance alloys - Enable fast material changes in order to produce multi-material or multi-functional products - Enable development of printing systems that can incorporate nano-structured materials (e.g. yarns

fromCNTsasreinforcements,nanofiberbasedfilterelementinproducts) - Novel substrate-ink combinations/improvement of materials - (Sustainable) availability of inks – standardisation - Consider raw material available to EU companies · Develop high performance processes using the new materials in order to get smart, smooth, accurate

dimensionandfeaturesforthefinalproduct · Identificationofexpositionscenariosofdevelopednanoinkmaterials• Expositionscenarioforprintedsystemsinendconsumerenvironment;Continousproductionprocesses

replacing batch processing• Totestthemanufacturingandmetrologysystembyproducingtest-caseproductsofhighsocialand

economic impact for Europe Target TRL 5-7 (4-7)Needed economical resources (public and private)3D printing --> 3D microprinting: 30 - 50 M€ Total resources alternative: 150 - 300 M€

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ExpectedImpact• EnablingEuropetocompeteattheforefrontofthe3Dmanufacturingrevolution · Widen the range of available 3D printing machines (for 3D objects or on 3D-shaped surfaces) and

metrology tools · Accelerate the transition of 3D nano manufacturing from mere prototyping towards production and

use · Prepare the next generation 3D printing material and processes · In the long term will lead into entire new production and consumption paradigms · Enabling manufacturing activities by SMEs to enter markets with innovations that were not possible

before (aspects like the cost of the 3D printing system as well as the cost for its use in SME produc-tion environment must be considered).

· New innovative products could offer a large spectrum of applications• Moresustainablemanufacturingofadvancedstructuresandcomplexgeometrieswhencomparedto

current average values · Reduction of at least 20% in the overall energy consumption · Reduction of at least 20% in the material usage SuggestionsonTypeofAction RIAReferencewithNfproposedactions

VC3-002-long

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Code Title of the actionVC1-S-004 Surfacefunctionalizationbystructurationininjectionmoulding,

embossing technologies and roll to rollTimeline 2015-2018Value Chain VC1Product Classes IdentifiedGapsP1-12: 3D printed Nanostruc-tures plastics as smart surfac-es,e.g.,lotuseffects

•Insomecasesnanoproductsarenotdevelopedtobescalableinproduction and again new innovation is necessary

P1-15: Injection moulded Na-nostructures plastics as smart surfaces,e.g.,lotuseffects

•Needfornanostructuredtoolsforinjectionmoulding

P1-19: General development of injection moulding processes for micro and nanostructured functionalized plastics

•Microinjectionmouldingnotstable/differentsizes

P1-20: Injection moulding of mi-cro and nanostructured plastics fordecorativeand/oranti-coun-terfeiting effect

•Durabilityofthemanufacturednanostructuresinthesurface

SpecificChallengeInjection moulding is the most used technology to produce plastic products. The technology has undergone little advancement in last decades. With nanotechnology new challenges can be faced:• Realizingfunctionalitiesandsurfacepropertiesthatcanbeincludeddirectlyinproduct• Replacing/modifyingsub-optimalprocesses: · Reduce cost · Reduce energy consumption · Reduce polution · Reduce health risksScopeThe aim of the projects should be:• toadvancethestate-of-theartofinjectionmouldingtoallowsurfacepatterningofsub-10µmstructures;• Totestthemanufacturingandmetrologysystembyproducingtest-caseproductsofhighsocialand

economic impact for Europe• Todevelophighperformancereliableandreproducibleinjectionmouldingmaterials(polymer,metals

ceramics)Target TRL 5-7Needed economical resources (public and private)NAExpectedImpactThe new injection moulding technology could be used develop functionalities such as: · Decorative effects · Super-hydrophobic effects · Optical effects · Anti-drag effects.• Thiscanleadto: · Smarter products · Less energy consumption in production lines · Products consisting of fewer materials --> less polution and more easy to recycleSuggestionsonTypeofAction RIA

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Code Title of the actionVC1-S-0051 DevelopmentofnovelextrusiontechniquesathighTRLTimeline 2015-2018Value Chain VC1Product Classes IdentifiedGapsP1-15: Injection moulded Na-nostructures plastics as smart surfaces,e.g.,lotuseffects

• Industrymightnotyetbeawareofwhatispossible,i.e.,theyarenot creating ideas

P1-16: Injection moulding of polymeric components for mi-cro optics and optics in general

• Optimizationofinjectionmouldingprocess-includingdevelopmentof plastic materials suitable this process

P1-19: General development of injection moulding processes for micro and nanostructured functionalized plastics

• Needfornanostructuredtoolsforinjectionmoulding

P1-20: Injection moulding of mi-cro and nanostructured plastics fordecorativeand/oranti-coun-terfeiting effect

• Characterizationtoolsneeded

Target TRL 5-7SuggestionsonTypeofAction RIA

1 This action was suggested within the online survey (June – July 2015). The information contained in the description ficheunderlineitsdifferentsource.

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Code Title of the actionVC1-S-006 Combinatorial approaches (mass parallel screening of material

properties)todevelopmaterialswithnewfuctionalitiescombiningchemicalcomposition,nanosizeandshapeeffect

Timeline >2022Product Classes IdentifiedGapsP1-32: Printed ceramics: TCO (TransparentConductiveOx-ides)

• Availability(use&price)ofspecializedmachinery

P1-33:Printedceramics:NewgenerationofLab-on-Chipwithbio-compatible(ortoxic)scaf-folds,andactiveinfluenceoncellgrowthanddifferentiation

• Industrymightnotyetbeawareofwhatispossible,i.e.,theyarenot creating ideas

• LackoffundingforR&DatTRLs3-5• Goodsimulationhelpstoscaleupproductionandgettomarket

faster• LackofawarenessatVentureCapitallevel

P1-34: Printed ceramics: Inte-gratedphotonicswithNLO(NonLinearOptics),electro-optic,py-roelectric,piezo-electric,etc.

• LackofawarenessatVentureCapitallevel• Industrymightnotyetbeawareofwhatispossible,i.e.,theyare

not creating ideas• Computingtime-->longdevelopmenttime• Goodsimulationhelpstoscaleupproductionandgettomarket

fasterP1-35: Printed ceramics: Other applications such as anti-coun-terfeitingtags,MEMS,catalysis,newphotovoltaics,newLEDs,etc.

• Industrymightnotyetbeawareofwhatispossible,i.e.,theyarenot creating ideas

• Computingtime-->longdevelopmenttime• LackoffundingforR&DatTRLs3-5• Materialspurity/qualityimprovewithtools

SpecificChallengeChallenging applications:• Superstrongmaterials• Energyeffiecientmaterials• Hybridbatteriesandacumulators• Materialswithtremendeousmultifunctionalpropertiesincomparisonwithindividiualones• LeadfreepiezomaterialsScope• Preparationofnewmaterials · Nanostructured materials · Hybrids at nanoscale · Technologies and new material concepts with property synergism.• Benchmarkthefunctionalitiesoftheavailablenanomaterials• InvestigatetheexactspecificationsofnanomaterialsrequiredfornewapplicationsTarget TRL 5Needed economical resources (public and private)NAExpectedImpactNASuggestionsonTypeofAction RIA

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Code Title of the actionVC1-M-001 Development and enhancement of inspection technologies and

methods for nanostructures over large areasTimeline 2015-2019Product Classes IdentifiedGapsP1-1: Printed metal • Characterizationtoolsneeded

• Howtocheckperformance• Toolsforinspection,failureanalysisandtestingof3Dintegrated

devicesP1-2:IntegratedCircuits;SolidStateMemoryDevices

• Characterizationtoolsneeded• Automaticdefectdetectionoverlargeareaswithsub20nmresolu-

tion.• Toolsforinspection,failureanalysisandtestingof3Dintegrated

devicesP1-3: Printed organic electron-ics

• Characterizationtoolsneeded• Howtocheckperformance• Toolsforinspection,failureanalysisandtestingof3Dintegrated

devicesP1-4: Anti-counterfeiting tags • Characterizationtoolsneeded

• Howtocheckperformance• Toolsforinspection,failureanalysisandtestingof3Dintegrateddevices

P1-22: Optical photonics inte-gratedonSi

• Characterizationtoolsneeded• Howtocheckperformance• Toolsforinspection,failureanalysisandtestingof3Dintegrated

devices• Metrologytoprove&predictmeantimebetweenfailures.Forspe-

cificapplicationneedtodevelopnewtoolsP1-26: Products on second hand production machinery

• Characterizationtoolsneeded

SpecificChallenge• Speedofscanningoverlargesurfaces• Minimizinghandlingtime/overhead• Deepsubmicronresolution,usingalsoe-beamorinterferometrictechnology• Stabilityandreproducibilityofmeasurements,• Focuscontrol• Sophisticatedalgorithmsfordefectclassification.Scope• Developnewtoolsformetrologyanddefectinspectionoverlargeareasincluding: · Scanning and stepping technology · Imaging technology for submicron features · Algorithmsfordefectdetectionandclassification. · Concepts for enabling of high throughput Target TRL 7-8Needed economical resources (public and private)NAExpectedImpact• Newtoolsformetrologyanddefectinspectionoverlargeareaswill: · Enable benchmarking of the functionalities of the available nanomaterials · Enableinvestigatingtheexactspecificationsofnanomaterialsrequiredfortheapplication. · Let Europe to keep its leading position in the production of advanced lithography equipment and the

Inspection equipment · Provideanaturalcomplementtoadvancedlithographyandinspectionequipementandcouldprofit

from synergies. · For some applications be a key differentiating factor in the production of large area electronics in the

form of automatic inspection equipment. SuggestionsonTypeofAction RIA

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Code Title of the actionVC1-M-002 Enhancedinterfacestoimprovesolid–gas,solid–liquid,andliq-

uid-gasinteractionsforbreakthroughapplicationsTimeline 2015-2020Product Classes IdentifiedGapsP1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Multifunctionalmaterialintegration• Insomecasesnanoproductsarenotdevelopedtobescalablein

production and again new innovation is necessary• Advancednon-traditionaloftensmallvolume

P1-33:Printedceramics:NewgenerationofLab-on-Chipwithbio-compatible(ortoxic)scaf-folds,andactiveinfluenceoncellgrowthanddifferentiation

• Industrymightnotyetbeawareofwhatispossible,i.e.,theyarenot creating ideas

• Identificationofapplicationareas(forinstancethestructuringcanbeused for anti-counterfeiting and/or labelling purposes - irrespective of whether it is a toy, medical component or others)

• Computingtime-->longdevelopmenttime• LackoffundingforR&DatTRLs3-5

SpecificChallengeNovelefficientcatalysisareofgreatdemandatdifferentfields:pharmacology,polymersysthenis,energy,etc. The challenges:• Harnessittomakebreakthroughindiversefields,• Enhancetechnologiesandimprovematerialsandsubstances.• Makeenhancedinterfacestoinfluencethetechnologyofnanoparticles,colloids,emulsions,etc.-• ittoveryimportantenergyandenvironmentalprocesses.Examples: · H2 production and separation, · Wastewaterpurification, · Numerous other Industrial processes.ScopeProjects should aim at:• Preparingnovelcatalysisforexistingandfuturetechnologies• Investigating,producingandcontrollingnanomaterials: · Preparing stable nano, micro emulsions, dispersions for different applications · Benchmarking the functionalities of the available nanomaterials · Investigatingtheexactspecificationsofnanomaterialsrequiredfortheapplication · Controlling the aggregation, agglomeration stabilities for different colloidal systems for the case of

ecology and pollution.• Developinginterfacesfor: · Gas separation · Waterpurificationandtreatment · ProcessIntensificationExample products: nanostructures to enhance coatings on beverage containers Target TRL 6Needed economical resources (public and private)NAExpectedImpact• EnablingEuropetoaddresstoenvironmentalproblems• Addresstomanufacturingandseparationprocessestowardssustainableindustrialfacilities• IncreasetheintegrationbetweenNMPandtraditionalenergysectorSuggestionsonTypeofAction RIA

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Code Title of the actionVC1-M-003 Industrial oriented research and demonstration on injection

mouldingofpolymeric-basedproductswithnanostructuredfunc-tionalized surfaces

Timeline 2019-2022Product Classes IdentifiedGapsP1-1: Printed metal • MetalbasedinksforpolymerdepositionP1-2:IntegratedCircuits;SolidStateMemoryDevices

• ChipencapsulationforIM

P1-3: Printed organic electron-ics

• Polymerinksforprinting

P1-6: OLED (organic light-emit-ting diode) lighting

• Enablebackinjectionwithorganicmaterials

P1-10: Plastic consumable bio-tech

• Multifunctionalmaterialintegration

P1-12: 3D printed Nanostruc-tures plastics as smart surfac-es,e.g.,lotuseffects

• Replicationofnanostructureonseveralsubstrates(bendable)• Reliabilityofnanostructures

P1-15: Injection moulded Na-nostructures plastics as smart surfaces,e.g.,lotuseffects

• Industrymightnotyetbeawareofwhatispossible,i.e.,theyarenot creating ideas

• Identificationofapplicationareas(forinstancethestructuringcanbeused for anti-counterfeiting and/or labelling purposes - irrespective of whether it is a toy, medical component or others)

• Theproductmightworkbuthastobeassembledandintegrated.This is a GAP because this has to be done often by another party

• Optimizationofinjectionmouldingprocess-includingdevelopmentof plastic materials suitable this process

P1-16: Injection moulding of polymeric components for mi-cro optics and optics in general

• Microinjectionmouldingnotstable/differentsizes• Goodsimulationhelpstoscaleupproductionandgettomarket

faster• Fornewdevelopmentyourelyon1-2partners(suppliers),whatif

one stops? --> delay in developmentP1-17: micro and nanostruc-tured transparent polymers for optical application

• Industrymightnotyetbeawareofwhatispossible,i.e.,theyarenot creating ideas

• Identificationofapplicationareas(forinstancethestructuringcanbeused for anti-counterfeiting and/or labelling purposes - irrespective of whether it is a toy, medical component or others)

• Capitalinvestmentavailability• Nopilotlineavailable/Moneyforpilotlines

P1-18:Customerspecificpack-aging solutions

• NeedfornanostructuredshimsforRollprocesses

P1-19: General development of injection moulding processes for micro and nanostructured functionalized plastics

• InvestmenttogofromlowTRLtohighTRL• Durabilityofthemanufacturednanostructuresinthesurface• Optimizationofinjectionmouldingprocess-includingdevelopment

of plastic materials suitable this process• Needfornanostructuredtoolsforinjectionmoulding

P1-20: Injection moulding of mi-cro and nanostructured plastics fordecorativeand/oranti-coun-terfeiting effect

• InvestmenttogofromlowTRLtohighTRL• Optimizationofinjectionmouldingprocess-includingdevelopment

of plastic materials suitable this process• Needfornanostructuredtoolsforinjectionmoulding

SpecificChallenge• Manufacturingofcomponentswithmultifunctionswithinsingleintegratedprocessfortransportation,

building, consumer goods and medicine.• Developmentofhighrobustcoatingsforbothcomponentsandmoulds• Achievingindustrialcycletimeswhilemaintaining100%fillingofnanostructures• Fabricationofhardmolds/toolsmadefromsteelwithhardcoatings(CrN,damondlikecarbon)withsub-

100nmfeatures.Difficultduetograinsizesofmaterial• DevelopmentoftechnologiesforstructureprotectionfrommechanicalwearWHILEmaintainingunique

properties/functionalities

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ScopeProjects should aim at:• Developingtoolsfor3Dcomponentsandfunctionintegration• Developingofcomponentsandconsumergoodssuitablemultifunctionswithlowcostinvestments• Developingmaterialsthatenablestrongcompatibilityforbiomimeticeffects• Demonstratefastcycletimeandcompletefixingforinjectionmouldingofstructureswithlateraldimen-

sions less than 100 nm• Demonstratefabricationofinjectionmouldingtoolsandinsertswithlateraldimensionslessthan100

nmTarget TRL 7Needed economical resources (public and private)5 - 8 M€ExpectedImpact• EnablingEuropetocompetewithlowaddedvalueproductscurrentlymanufacturedinFarEast• Contributingtoreinforceentiremanufacturingvaluechainstartingfromtoolsmanufacturestogood

producers to end-users.• Reductionofmaterialsand“nano”taggingallowformoreeasyrecycling• Improvedproductsduetoimplementationofnewfunctionalities;i.e.superhydrophobicity,colouring/

decoration, anti-counterfeit, drag-reduction• Fewermaterialstogetspecificproperties · Energy saving (for example vacuum processes can be reduced) · Less chemicals, particles, additives --> more safe products SuggestionsonTypeofAction RIA

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Code Title of the actionVC1-M-004 Ultra-highbarriertechnologiesforflexibleorganicbasedprinted

technologies/devices(i.e.OLED,OPV,OTFT)Timeline 2019-2022Product Classes IdentifiedGapsP1-1: Printed metal • BendableprintedcircuitsP1-3: Printed organic electron-ics

• Materialspurity/qualityimprovewithtools• compatibility/acceptance• High(reliable)lifetime/barrier(preventingwatertoreachactive

material)• Durabilityofthemanufacturednanostructuresinthesurface

P1-6: OLED (organic light-emit-ting diode) lighting

• Materialspurity/qualityimprovewithtools• Compatibility/acceptance• High(reliable)lifetime/barrier(preventingwatertoreachactive

material)• Durabilityofthemanufacturednanostructuresinthesurface

P1-7: OLED (organic light-emit-ting diode) screens

• Materialspurity/qualityimprovewithtools• Compatibility/acceptance• High(reliable)lifetime/barrier(preventingwatertoreachactive

material)• Durabilityofthemanufacturednanostructuresinthesurface

P1-9:Printedpowersupply:Or-ganic Photo Voltaic (OPV) - Fuel Cells - battery - catalysis

• Materialspurity/qualityimprovewithtools• Compatibility/acceptance• High(reliable)lifetime/barrier(preventingwatertoreachactive

material)• Durabilityofthemanufacturednanostructuresinthesurface

SpecificChallenge• Manufacturingofultra-highbarriertechnologiesforhighlyrobustdevices · Harsh environment · High temperature · High relative humidity• Manufacturingofdevicesenablehighintegrationwithinexistingcomponentsfortransportation,building

and consumer goodsScopeProjects should aim at:• Developingtoolshighprecisionprintingforlowcostandhighthroughputproduction• Developingof3Dbendabledevicesforhighdegreeofintegration• Alsoinclude: · Novelcoatingsoninjectionmouldstospecificallyhelpintroductionofnanostructures-->medical

devices/microfluidics. · Coating enable patterning of mould and help moulding process. · Integrateseasilyintocurrentprocess-->doesnotneedspecificmouldfabricationchangetoallow

use of nano-structured shims. Target TRL 7-8Needed economical resources (public and private)NAExpectedImpact• Contributingtoreinforceentiremanufacturingvaluechainstartingformtoolsmanufacturestogood

producers to end-users.• CoatingapproachalsopotentialtohelprecycleofmouldSuggestionsonTypeofAction RIA

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Code Title of the actionVC1-M-005 Development of nanocomposite multilayered and multifunctional

plastic meshes for implantsTimeline 2019-2022Product Classes IdentifiedGapsP1-10: Plastic consumable bio-tech

• Multifunctionalmaterialintegration

P1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Insomecasesnanoproductsarenotdevelopedtobescalableinproduction and again new innovation is necessary

P1-33:Printedceramics:NewgenerationofLab-on-Chipwithbio-compatible(ortoxic)sca-folds,andactiveinfluenceoncellgrowthanddifferentiation…

• Characterizationtoolsneeded

SpecificChallengeDevelop multilayered multifunctional nanostructured material having• Structuralandsurfacefunctionalpropertiesallowingbioresorptiononexternallayers• Displayingadhesioninoneexternallayer• DisplayingadhesionandcellgrowthontheotherexternallayerScope• Simplifythesurgicalproceduresinintraperitonealsurgery,suchas: · Easyhandlingforoptimalflexibilityandoptimalshapememory · Easierandfasterfixationtoparietaltissueforself-adhesiveproperties · Noneedofadditionaldevicesforfixationtoparietaltissues• Providepreventionoforgansadhesions,beforebioresorptionoftheanti-adhesionlayerandthesimul-

taneous neo-peritoneum regeneration. • Providefirmstabilityofthedevicetoparietaltissue,beforebioresorptionofadhesivelayerandsimul-

taneousfibroblastsinfiltrationforthedeviceintegrationinthetissues.Target TRL 6Needed economical resources (public and private)NAExpectedImpactSocial and health impact: • Simplifythesurgicalproceduresinintraperitonealsurgery,suchas:easyhandlingforoptimalflexibility

andoptimalshapememory;easierandfasterfixationtoparietaltissueforself-adhesiveproperties;noneedofadditionaldevicesforfixationtoparietaltissues

• Providepreventionofbowelsadhesions,beforebioresorptionoftheanti-adhesionlayerandthesimul-taneous neo-peritoneum regeneration.

• Providefirmstabilityofthedevicetoparietaltissue,beforebioresorptionofadhesivelayerandsimul-taneousfibroblastsinfiltrationforthedeviceintegrationinthetissues.

Industrial / Economic:• AllowSMEtobemorecompetitivethanlargecompanyactorsinthebiomedicalimplantsectorentering

a market that only for Hernia Repair is worth 4b$ with a CAG of 7.5%SuggestionsonTypeofAction RIA

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Implementation Roadmap on value chains and related pilot lines 99

Code Title of the actionVC1-L-001 BreakthroughHybridsmartmaterials&systemsTimeline >2022Product Classes IdentifiedGapsP1-14: 3D printed Hybrid optics for LED and lightning

• Multifunctionalmaterialintegration• Replaceprintedcircuitboard(PCB)-->disruptive(barriertoentry)• Insomecasesnanoproductsarenotdevelopedtobescalablein

production and again new innovation is necessary• Advancednon-traditionaloftensmallvolume

P1-30:CMOS-fabforbiddenma-terials

• Compatibility/acceptance• Abinitiomodellingofelectricalpropertiesofnewmaterials• Multi-physicsmodellingonsmallscalesstillposesabigchallenge

on nano products• Materialspurity/qualityimprovewithtools

P1-31:NonmainstreamMEMS • Multifunctionalmaterialintegration• Insomecasesnanoproductsarenotdevelopedtobescalablein

production and again new innovation is necessary• TotalCostofOwnership• Availability(use&price)ofspecializedmachinery

SpecificChallengeChallenging applications: · Superstrong materials · Energyefficientmaterials · Hybrid batteries and acumulators · Materials for designing the Buildings of the Future · Materials for designing the vehicles of the Future.Scope• Combinationoforganicandinorganicnatureblocksatthenanoscaleandhybridorganic-inorganic

chemistry to prepare hybrid materials for different applications including: · Smart consruction materials for functionalities in smart buildings · Smart hybrid materials for sensor functionalities in means of transportation · Smart hybrid materials for sensor functionalities in Industry · Hybrid batteries and accumulators · Etc. Target TRL 6-7Needed economical resources (public and private)NAExpectedImpactNASuggestionsonTypeofAction RIA

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Code Title of the actionVC1-L-002 NewgenerationofdisruptiveinjectionmouldingmachinesTimeline 2019-2022Product Classes IdentifiedGapsP1-15: Injection moulded Na-nostructures plastics as smart surfaces,e.g.,lotuseffects

• Industrymightnotyetbeawareofwhatispossible,i.e.,theyarenot creating ideas

• InvestmenttogofromlowTRLtohighTRL• Capitalinvestmentavailability

P1-16: Injection moulding of polymeric components for mi-cro optics and optics in general

• InvestmenttogofromlowTRLtohighTRL• Capitalinvestmentavailability• Processeswithtoolingneedsometimesiterationswhichleadto

an important time to market => hard competition with “low costs” countries.

P1-19: General development of injection moulding processes for micro and nanostructured functionalized plastics

• InvestmenttogofromlowTRLtohighTRL• Interfacecommunicationbetweenpartners(preprod-->marketexp)• Optimizationofinjectionmouldingprocess-includingdevelopment

of plastic materials suitable this processP1-20: Injection moulding of mi-cro and nanostructured plastics fordecorativeand/oranti-coun-terfeiting effect

• InvestmenttogofromlowTRLtohighTRL• Affordablelithotechnologyforsub-40nm• Optimizationofinjectionmouldingprocess-includingdevelopment

of plastic materials suitable this processP1-21: nanostructure inorganic (MicroPowderinjectionmould-ing)

• Industrymightnotyetbeawareofwhatispossible,i.e.,theyarenot creating ideas

• Identificationofapplicationareas(forinstancethestructuringcanbeused for anti-counterfeiting and/or labelling purposes - irrespective of whether it is a toy, medical component or others)

• CapitalinvestmentavailabilitySpecificChallengeNAScopeProjects should aim at:• Developingofinjectionmouldingtoolsenablinghighdegreeofreplication: · High uniformity · High precision (nanometer scale)• DesignofNewProductionLinesutilizingnanomaterialsTarget TRL 7Needed economical resources (public and private)NAExpectedImpactNASuggestionsonTypeofAction RIA

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Implementation Roadmap on value chains and related pilot lines 101

Code Title of the actionVC1-L-0032 Development of customized solutions for printing processesTimeline >2022Product Classes IdentifiedGapsP1-1: Printed metal • MultifunctionalmaterialintegrationP1-3: Printed organic electron-ics

• Advancednon-traditionaloftensmallvolume

P1-9:Printedpower supply:Organic Photo Voltaics (OPV) - Fuel Cells - battery - catalysis

• ReplacePCBboards-->disruptive(barriertoentry)

P1-12: 3D printed Nanostruc-tures plastics as smart surfac-es,e.g.,lotuseffects

• Insomecasesnanoproductsarenotdevelopedtobescalableinproduction and again new innovation is necessary

Other product classes suggestedP1-13: 3D printed Polymeric micro-opticslikelensesorpyr-amids

P1-29:3DprintedPolymericMEMSformulti-useon-chip

P1-14: 3D printed Hybrid optics for LED and lightning

P1-32:Printedceramics:TCO(TransparentConductiveOxides)

P1-23: 3D printed Photonic wirebondsformulti-chipopti-cal connection

P1-33:Printedceramics:NewgenerationofLab-on-Chipwithbio-compatible(ortoxic)scaffolds,andactiveinfluenceoncellgrowthand differentiation

P1-24: 3D printed microparts for on-chip free-space optical coupling

P1-34:Printedceramics:IntegratedphotonicswithNLO(NonLin-earOptics),electro-optic,pyroelectric,piezo-electric,etc.

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters

P1-35: Printed ceramics: Other applications such as anti-coun-terfeitingtags,MEMS,catalysis,newphotovoltaics,newLEDs,…

P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

P1-36:Printedinky(atlowtemperatureandonlowcostmaterialse.g polymers and paper)

Target TRL 5-6

2 This action was suggested within the online survey (June – July 2015). The information contained in the description ficheunderlineitsdifferentsource.

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3 This action was suggested within the online survey (June – July 2015). The information contained in the description ficheunderlineitsdifferentsource.

Code Title of the actionVC1-L-0043 Development and upscaling of 3D processes (e.g. direct laser

writingandstereolithography)formorecomplexnanostructuredcomponents,forabreadthofapplicationse.g.healthandPV

Timeline >2022Product Classes IdentifiedGapsP1-1: Printed metal • MultifunctionalmaterialintegrationP1-3: Printed organic electron-ics

• Insomecasesnanoproductsarenotdevelopedtobescaleableinproduction and again new innovation is necessary

P1-9:Printedpower supply:Organic Photo Voltaics (OPV) - Fuel Cells - battery - catalysis

• Cost&technology(unmstruct),for3Dtechnologynotavailable

P1-12: 3D printed Nanostruc-tures plastics as smart surfac-es,e.g.,lotuseffects

• Toolsforinspection,failureanalysisandtestingof3-Dintegrateddevices

Other product classes suggestedP1-13: 3D printed Polymeric micro-opticslikelensesorpyr-amids

P1-29:3DprintedPolymericMEMSformulti-useon-chip

P1-14: 3D printed Hybrid optics for LED and lightning

P1-32:Printedceramics:TCO(TransparentConductiveOxides)

P1-23: 3D printed Photonic wirebondsformulti-chipopti-cal connection

P1-33:Printedceramics:NewgenerationofLab-on-Chipwithbio-compatible(ortoxic)scaffolds,andactiveinfluenceoncellgrowthand differentiation

P1-24: 3D printed microparts for on-chip free-space optical coupling

P1-34:Printedceramics:IntegratedphotonicswithNLO(NonLin-earOptics),electro-optic,pyroelectric,piezo-electric,etc

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters

P1-35: Printed ceramics: Other applications such as anti-counter-feitingtags,MEMS,catalysis,newphotovoltaics,newLEDs,etc.

P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

P1-36:Printedinky(atlowtemperatureandonlowcostmaterialse.g polymers and paper)

Target TRL 5-6

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7 Appendix II

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7 Appendix II

AppendixII- VC2 - Nano-enabled, depollutant and self-cleaning surfaces Actions Description Fiches

ThisappendixcontainsoneactionficheforeachVC2action,whichincludes,whenapplicable,ac-tioncode,title,timeline,productclassesandgaps,specificchallenges(i.e.theneedfortheaction),scope (i.e. the list of objectives), TRL expected, needed economical resources (i.e. the suggested economic size of the projects), impact (i.e. the expected social and economic outcome) and type ofaction.IftheactionhassynergieswithtopicsidentifiedintheNANOfutures Integrated Research and Industrial Roadmap for European Nanotechnology (available at http://www.nanofutures.eu/documents), reference to the Nf topic codes is presented.

Code Title of the actionVC2-S-001 Advanced industrial research to enhance the performance of func-

tional nanocoatingsTimeline 2015-2018Product Classes IdentifiedGapsP2-4: Nanostructured surfaces with antimicrobial, antiviral,biocompatible,anti-adhesiveproperties for biomedical appli-cations(e.g.,medicaldevices,implants,hospitalrooms,etc.)

• Researchfunding• Scale-up• LackofEuropeanpatents/lowcostofownership

P2-6:Self-healing,self-cleaning,high-gloss,anti-scratchingna-nocoatings(e.g.,fortransport,constructionindustries,etc.)

• Fundingtogenerateadequateprototype• LackofEuropeanpatents/lowcostofownership• Interior/exteriorplasticssurfaces

P2-7.1: Nanostructured coat-ings for thermal management (e.g.,coolingandIRreflection)

• Researchfunding• LackofEuropeanpatents/lowcostofownership

P2-7.2: Nanostructured coat-ings forUV screening (e.g.,cosmetics,sun-screenprotec-tion,etc.)

• Researchfunding• LackofEuropeanpatents/lowcostofownership

P2-8: Anti-pollutant nanocoat-ings for protection of heritage monuments and buildings

• Fundingtogenerateadequateprototype• LackofEuropeanpatents/lowcostofownership

P2-9: Nanocoatings for mechan-icallyenhancedsurfaces(e.g.,increasedabrasionresistance,lowfriction,etc.)

• Researchfunding• Scale-up• Demonstratorstobevalidatedinindustrialscale• Investmentinnewapplicationprocesses

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P2-10:Nanocoatingswithsuperhydrophobic surface properties (e.g.,forprotectionofbuildings,bridges,roads,metallicstruc-tures,etc.)

• Fundingtogenerateadequateprototype• Scale-up• LackofEuropeanpatents/lowcostofownership• Demonstratorstobevalidatedinindustrialscale

P2-13: Nanocoatings for the garmentindustrywithstain-re-sistant,anti-odour,anti-microbi-al,conducting,waterrepellent,etc. properties

• Fundingtogenerateadequateprototype• Scale-up• LackofEuropeanpatents/lowcostofownership

SpecificChallenge• Improvetheperformanceofnano-enabledsurfaces(e.g.,durability,friction,washingresistance,bio-

compatibility, etc) at competing prices.• Scaleupfromlabscaletopilotproduction.• Controlofcoatingdepositionparametersthatmayaffectthesubstratesintegrity.ScopeProjects should aim at:• Manufacturingofnanocoatingswithenhancedperformance(e.g.,increasedabrasionresistance,low

friction, corrosion resistance, anti-pollutant, self-cleaning, self-healing, stain resistance, anti-odor, an-timicrobial, antiviral, increased selectivity, etc) for the transportation, construction, textiles, biomedical, energy and environmental sectors.

• Upgradingexistingproductionmethods(e.g.,injectionmolding,roll-2-rollandsheet-2-sheetprintingpresentlylimitedtofeaturesreplicationintherangeof10μm)tonewinnovativetechnologiesenablingthe replication of nanocoatings features in the sub-100 nm range.

• Controlofsurfacefunctionalproperties(e.g.,hydrophobicity,mechanical,thermal,barrier,electrical,corrosion-resistant, anti-fouling, water repellent properties, etc.) of nanosurfaces.

• Scaling-upoflabnanoproductionprocesses(TRL4-5)topilotproductionlines.Differenttechnologiesfor the production of nano-enabled surfaces may be considered.

• Non-technologicalaspectslikestandardization,regulatoryissues,useracceptance,HSEaspects,LCA,etc should be also addressed.

Target TRL 7-8Needed economical resources (public and private)NAExpectedImpact• Integrationofstate-of-the-artnanotechnologyinthetraditionalproductionofcoatings/surfaceswillgive

a market advantage to the European coatings sector via the development of functional nanocoatings (e.g., super hydrophobic, anti-pollutant, antimicrobial/antiviral, corrosion/abrasion resistant, self-healing, highlyselective,anti-reflection,luminescent,etc).

• Energyefficientandsafeproductionprocesses.• Eliminationofexpensiveandtime-consumingpost-productionprocesses.• Reductionofbiofoulingaswellasofenergyuse,repairsandmaintenanceassociatedwithwater-based

drag and corrosion.• Potentialreductionincarbondioxide(CO2) emissions. SuggestionsonTypeofAction RIA

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Code Title of the actionVC2-S-002 PilotLinesforthemanufacturingand/orfunctionalizationofna-

nosurfaces for novel applicationsTimeline 2015-2018Product Classes IdentifiedGapsP2-1.2: Nanostructured sur-faces for production of clean energy(e.g.,airturbines,etc.)

• High-performanceanti-icingcoatingsforwindturbines

P2-2:Photocatalysisforwaterand indoor and outdoor air pu-rification

• Performanceofnewmaterials• Scale-up• Investmentrisktaking• Education/trainingoffutureworkers/students/teachers

P2-3: Nanostructured surfaces with increasedselectivityto-wardstracecontaminantsforwatermanagement

• Performanceofnewmaterials• Scale-up• Investmentrisktaking• Efficiencyandcosteffectivenessofproduction

P2-4: Nanostructured surfaces with antimicrobial, antiviral,biocompatible,anti-adhesiveproperties for biomedical appli-cations(e.g.,medicaldevices,implants,hospitalrooms,etc.)

• Applicationofsonochemicalprocessesneedtobescaledupinorderto treat wide surface areas at high speed to develop antibacterial and antifungal nanoparticles enriched surfaces

P2-5: Multifunctional nanocoat-ingswithimprovedmechanical,electrical,thermal,barrierandchemical properties

• Easy-to-emptycoatingsforpackagingwithvaluableingredientse.g.pharma

P2-9: Nanocoatings for mechan-icallyenhancedsurfaces(e.g.,increasedabrasionresistance,lowfriction,etc.)

• Tribologicalcoatingsformetalsusingchemicalnanotechnologyprocesses for cost reduction (compared with PVD)

P2-11:Nanocoatingswithen-hancedsurfacewaterconden-sation properties for moisture collection

• Performanceofnewmaterials• Investmentrisktaking

P2-12:Nanocoatingswithcorro-sion-resistant and anti-fouling properties for protection of liq-uid and gas handling equipment and pipelines

• Performanceofnewmaterials• Scale-up• Investmentrisktaking

SpecificChallenge• Scaleupoflabscaleproductionmethodstopilot-scalelines.ScopeProjects should aim at:• Manufacturingoflowcost,highefficiencyandlowenvironmentalimpactnanosurfacesforcleanenergy,

watertreatment,indoorandoutdoorairpurification,thermalmanagement,biomedical,transport,con-struction, heritage protection, textiles, safety, etc., applications.

Target TRL 7Needed economical resources (public and private)NAExpectedImpact• IncreasethecompetitivenessofEuropeanindustriesandexpandtheirmarkettopotentialnon-EU

countries.• IncreasethecompetitivenessofEuropeanSMEsengagedinenvironmental,biomedical,textile,automo-

tive sectors, etc.• Contributetothesocialgrandchallengesofourtime(e.g.,sustainablesolutionsfortheproductionof

clean energy and clean water, etc.). SuggestionsonTypeofAction RIA

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Code Title of the actionVC2-S-003 Novel processes and technologies for engineering surface modi-

ficationandfunctionalitiesincorporationTimeline 2015-2018Product Classes IdentifiedGapsP2-2:Photocatalysisforwaterand indoor and outdoor air pu-rification

• Newmaterialpropertiesfornewmarkets• Lackofdurablefunctionalsurfacetreatment/easyperformance

P2-11:Nanocoatingswithen-hancedsurfacewaterconden-sation properties for moisture collection

• Performanceofnewmaterials• Investmentinnewapplicationprocesses

SpecificChallenge• Plasmatreatmentcouldallowmodificationofthechemicalcompositionofasurfacethusenablingthe

productionofmultifunctionalsurfacesthatcannotbeeasilyproducedbyconventionalfinishingmethods.• Designandoptimizationofatmosphericplasmaprocessintermsofprocessversatilityinordertoallow

technology transfer to industry.Scope• Developmentanddemonstrationtorelevantindustrialenvironmentsofhighthroughputsurfacemodifica-

tion techniques (e.g., 2D and 3D plasma treatment, etc.).• Novelprocessesforsurfacemodificationandfunctionalization.Manufacturingofengineerednanosur-

faces with super-hydrophobicity, anti-fouling, drag reduction, improved adhesion, increased abrasion resistance, low friction, corrosion resistance, anti-pollutant, self-cleaning, self-healing, stain resistance, anti-odor, antimicrobial, antiviral, increased selectivity, etc. properties.

• Proposalsshouldincludeanoutlineofexploitationandabusinessplan.Target TRL 6-7Needed economical resources (public and private)NAExpectedImpact• Improvedperformance,energyefficiency,environmentalimpact.• Higherlevelofautomationandlowerproductiontimescomparedtocurrenttechnologies.• Newmarketopportunitiesviaintroductionofanovelprocessinexistingproductionlines.• Improvementintechnicalknowledgeconcerningmanufacturingprocessesofsurfaces.• Significantimprovementsinindustrialproductivityandcostcompetitivenessincomparisonwithtraditional

processes. SuggestionsonTypeofAction RIAReferencewithNfproposedactions

VC3-001-short, VC3-009-short and VC3-012-short.

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Code Title of the actionVC2-S-004 Advanced research and demonstration on nanostructured sur-

facesforrenewableenergyproductionTimeline 2015-2018Product Classes IdentifiedGapsP2-1.1: Nanostructured sur-faces for production of clean energy(e.g.,photosynthesis,photovoltaics, solar thermalcollectors,etc.)

• Performanceofnewmaterials• Scalability• Demonstratorstobevalidatedatindustrialscale• Longtermstableantidust-coatingsforsolarapplications

P2-1.2: Nanostructured sur-faces for production of clean energy(e.g.,airturbines,etc.)

• Performanceofnewmaterials• Scalability• Demonstratorstobevalidatedatindustrialscale

SpecificChallenge• Novelbreakthroughtechnologiesforenergyproductionandconversion.• Nanostructuredsurfacesexhibitingself-cleaningandanti-icingpropertiesarenotyetdurable.• Supplychainsdonotexistforthesenanostructuredsurfaces.• Scalablesynthesismethods.Scope• Novelmaterialswithtunablesurfacechemicalandmorphologicalstructuresforcleanenergyapplica-

tions.• Materialssynthesisandenergyharvestingbasedonefficientandhighlyselectivemechanisms.• MaintainingsurfacecleanlinessofsolarPVandsolarthermalcollectorstominimizelossofefficiency

during long term operation• Preventingicebuilduponwindturbine,powersupplyanddistributionnetworks.Target TRL 6-7Needed economical resources (public and private)NAExpectedImpact• Novelmaterialsdesignresultingincreationofnewknowledgeandworkforce• Significantreductioninthecostofrenewableenergy.• IncreasedadoptionofthesetechnologiesinEurope• Reducedemissions.• Efficientenergyproduction,conversion,transmission,storageanduse.• Ensuringclean,reliable,andaffordableenergytoagrowingpopulace• SecuringsupplyofenergyatEuropeanlevelSuggestionsonTypeofAction RIA

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Code Title of the actionVC2-M-001 Large scale demonstrators on the use of nano-enabled surface

technologiesforcleanair,waterandenergywithinvolvementofEuropean municipalities

Timeline 2019-2022Product Classes IdentifiedGapsP2-12:Nanocoatingswithcorro-sion-resistant and anti-fouling properties for protection of liq-uid and gas handling equipment and pipelines

• Performanceofnewmaterials• Scale-up• ISOstandardization

SpecificChallenge• Cleanerandmoreefficientenergyproduction• IndoorandoutdoorairpurificationbyphotocatalysisScope• Projectsshouldaddresstheuseofgreenprocessesfortheproductionofcleanair,waterandenergy• InvolvementofinnovativepublicprocurementfundinginstrumentsTarget TRL 7Needed economical resources (public and private)NAExpectedImpact• ImprovedperformanceSuggestionsonTypeofAction IA

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Code Title of the actionVC2-M-002 Environmental friendly processes to activate functional nano-

surfaces and to incorporate nanoparticlesTimeline 2019-2022Product Classes IdentifiedGapsP2-4: Nanostructured surfaces withantimicrobial,antiviral,bio-compatible,anti-adhesiveprop-erties for biomedical

• Integrationofnanoparticleswithexistentsurfaces• REACH• Publictransportation

P2-10:Nanocoatingswithsuperhydrophobic surface properties (e.g.,forprotectionofbuildings,bridges,roads,metallicstruc-tures,etc.)

• Integrationofnanoparticleswithexistentsurfacesandtheircharac-terisation

• Opticalsurfaces

P2-13: Nanocoatings for the garmentindustrywithstain-re-sistant,anti-odour,anti-microbi-al,conducting,waterrepellent,etc. properties

• Environmentalfriendlyflameretardantcoatings

SpecificChallenge• Developmentoflasersources(femto-picosecond)enablingfastscanandetching.• Reactivephysicaletchingbybeamsunderhighandlowvacuum.• Surfacesshouldbeeasilydesignedatdifferentlevelsofstructurehierarchy.• Cheapandsimpletechnologiesforattaching/assemblingvarioustypesofnanoparticles(e.g.,nature,

size, shape) to different types of surfaces (e.g., nature, shape). • Bottom-upandtop-downtechnologies.Scope• Projectsshouldaddressthedevelopmentofhighpulselaserforengraving,enablingprecisionandfast

processes for physical etching as alternatives to existing chemical processes• Lowcostandrelativelysimpletechnologiesfornanostructuredsurfaces.Target TRL 6Needed economical resources (public and private)NAExpectedImpact• Ahigherlevelofautomationandlowerproductiontimescomparedtocurrenttechnologies.• Improvementintechnicalknowledgeconcerningmanufacturingprocessesofsurfaces.SuggestionsonTypeofAction RIA

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Code Title of the actionVC2-M-003 Supportinnovativenewtechnologiesforefficienthandlingand

manipulation of nanoparticlesTimeline 2019-2022Product Classes IdentifiedGapsP2-2:Photocatalysisforwaterand indoor and outdoor air pu-rification

• Ultrasoundprocessingofnanoparticlesforefficientwatercleaningor removal of rare earth metals from highly diluted solutions

P2-6:Self-healing,self-cleaning,high-gloss,anti-scratchingna-nocoatings(e.g.,fortransport,constructionindustries,etc.)

• Processingtechniquesofnanocapsulesforself-healinge.g.corro-sion protective coatings

P2-12:Nanocoatingswithcorro-sion-resistant and anti-fouling properties for protection of liq-uid and gas handling equipment and pipelines

• Optimizemixing/dispersion/characterisationtechnology• Quantificationoftoolsandrecognizedhandlingprotocols

P2-13: Nanocoatings for the garmentindustrywithstain-re-sistant,anti-odour,anti-microbi-al,conducting,waterrepellent,etc. properties

• Optimizemixing/dispersion/characterisationtechnology

P2-14:Nanopigmentswithin-creased luminosity and long af-terglowforsafetyapplications(e.g.,safetysigns,safety-wayguidance systems for office buildings, underground sta-tions,tunnels,etc.)

• Optimizemixing/dispersion/characterisationtechnology

SpecificChallenge• Efficienthandlingofnanostructuredpowdersnotleadingtoaerosolisation• ReducedchancesofaerosolreleasetotheworkplaceduringgenerationofNPsinthegasphase• Reducedoccupationalexposure(inhalation/dermal)tonanoparticles(e.g.,duringspraydrying,pro-

cessing and packaging of the dry powder)• Substitutionofparticularlyhazardouschemicalsandprocesseswithlessharmfulones.Scope• Newmethodsandtechnologiestoidentifyandmanipulatediversenanoparticles(e.g.,freezedrying,

mixing, coating, etc) without any eco- and human toxic risks. Target TRL 6Needed economical resources (public and private)NAExpectedImpact• MethodsandtechnologiescompliantwithREACHregulationsSuggestionsonTypeofAction CSA

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Code Title of the actionVC2-M-004 Development of sustainable processes for in-line treatment to

producenano-basedantimicrobial,antifungalsurfacesTimeline 2019-2022Product Classes IdentifiedGapsP2-4: Nanostructured surfaces with antimicrobial, antiviral,biocompatible,anti-adhesiveproperties for biomedical appli-cations(e.g.,medicaldevices,implants,hospitalrooms,etc.)

• Quantificationoftoolsandrecognizedhandlingprotocols• Integrationofnanoparticleswithexistentsurfaces

P2-13: Nanocoatings for the garmentindustrywithstain-re-sistant,anti-odour,anti-microbi-al,conducting,waterrepellent,etc. properties

• Optimizemixing/dispersion/characterisationtechnology

SpecificChallenge• Deploycosteffective,sustainableandrobustnewmanufacturingroutesforin-situsynthesisofnano-

composite functional surfaces. • AllowSMEsplayacentralroleasenablingtechnologysuppliersfornano-basedmaterialtreatment

processes.Scope• Bacteriaandpathogenagentsproliferationisoneofthemainsourcesofprolongedhospitalizationand

diseases breeding. Safety measures in all context of daily life are necessary to improve the citizen safety, quality of life and workers’ productivity. Antibacterial, antifungal functionalities on different classes of conventional surfaces provide a solution with a broad impact on society, health and wellbeing.

• Deploymentofflexiblenanotechnologybasedprocessescapableoffunctionalizingdifferentmaterialsare needed to attain antibacterial functionalities for a broad spectrum of applications: medical and health, upholstery employed in hospitals, hotels, restaurants, home upholstery; furniture and indoor appliances, private and public means of transport, sports and technical wear.

Target TRL 6-7Needed economical resources (public and private)NAExpectedImpact• Healthandsafety:i)applicationofsaferprotocolsforinfectiondiseasesprevention;ii)dramaticdecrease

of health care cost due to reduced hospitalization time; iii) substantial decrease of death rate for acquired infections during hospitalization time;

• Social:i)improvementofqualityoflifeespeciallyforelderlies;ii)saferpublicenvironments;iii)saferpublic transport; iv) creation of new jobs;

• Economic:i)opportunitiesforboostingSMEsbusinessastechnologyproviders,ii)enhancementofEU technical textile industry competitiveness; iii) reinforcement of automotive industry suppliers sector involved in the production of woven and nonwoven textiles for car interiors (e.g. seats covering, carpets, canopy and trunk coverings) and outdoor components (e.g. wheel well liners).

SuggestionsonTypeofAction RIA

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Code Title of the actionVC2-L-001 Research on antimicrobial surfaces active under visible lightTimeline >2022Product Classes IdentifiedGapsP2-4: Nanostructured surfaces with antimicrobial, antiviral,biocompatible,anti-adhesiveproperties for biomedical appli-cations(e.g.,medicaldevices,implants,hospitalrooms,etc.)

• Quantificationoftoolsandrecognizedhandlingprotocols• Integrationofnanoparticleswithexistentsurfaces

P2-5: Multifunctional nanocoat-ingswithimprovedmechanical,electrical,thermal,barrierandchemical properties

• Quantificationoftoolsandrecognizedhandlingprotocols• Integrationofnanoparticleswithexistentsurfaces

P2-13: Nanocoatings for the garmentindustrywithstain-re-sistant,anti-odour,anti-microbi-al,conducting,waterrepellent,etc. properties

• Quantificationoftoolsandrecognizedhandlingprotocols• Integrationofnanoparticleswithexistentsurfaces

P2-14:Nanopigmentswithin-creased luminosity and long af-terglowforsafetyapplications(e.g.,safetysigns,safety-wayguidance systems for office buildings, underground sta-tions,tunnels,etc.)

• Quantificationoftoolsandrecognizedhandlingprotocols• Integrationofnanoparticleswithexistentsurfaces

SpecificChallenge• DisinfectionmethodsusingUV-inducedprocesseshavebeenfoundtosufferfromalackofresidual

effect, highlighting the need for further development of disinfection techniques to address these short-comings

• Inabilityoftitaniatoefficientlyusesolarlightwhichiscomposedofonly3-5%UVascomparedtoap-prox. 43% visible light.

• Silvermodifiedcompositespresentanovelclassofhybridphotocatalystswhichposesantibacterialand/or antiviral action in both dark and light conditions.

Scope• Overcomethelimitationintheapplicationoftitaniaresultingfromlowquantumyieldandnecessityto

use UV irradiation• EnhancementofvisiblelightabsorptionandimprovementofthecatalyticactivityofZnOviafunctionali-

zation with noble metals, small bandgap oxide and QDs. Target TRL 7Needed economical resources (public and private)NAExpectedImpactNASuggestionsonTypeofAction RIA

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Code Title of the actionVC2-L-002 Increase the durability of nanocoatings in order to supply tradi-

tionalindustrieswithaffordableaddedvalueproductsTimeline >2022Product Classes IdentifiedGapsP2-6:Self-healing,self-cleaning,high-gloss,anti-scratchingna-nocoatings(e.g.,fortransport,constructionindustries,etc.)

• Clarityofcost-benefitratio• Lowcostefficientprocesses/products

P2-9: Nanocoatings for mechan-icallyenhancedsurfaces(e.g.,increasedabrasionresistance,lowfriction,etc.)

• Lowcostefficientprocesses/products• MultiscalebusinessforEuropeanbenefit

P2-10:Nanocoatingswithsuperhydrophobic surface properties (e.g.,forprotectionofbuildings,bridges,roads,metallicstruc-tures,etc.)

• Lowcostefficientprocesses/products• MultiscalebusinessforEuropeanbenefit

P2-13: Nanocoatings for the garmentindustrywithstain-re-sistant,anti-odour,anti-microbi-al,conducting,waterrepellent,etc. properties

• Lowcostefficientprocesses/products

SpecificChallenge• Nanocoatingsprocessingmethodsforlargeareasneedtoi)attainfastprocessingandhighthroughput

as well as treatment uniformity; ii) decrease processing costs; iii) guarantee safety of products and processing methods as well as durability of functionalities.

• Theapplicationofnanocoatingstotheconstructionsectorandforculturalheritagemaintenanceandpreservation involves the use of reliable portable tools complying with ergonomic and safety standards.

• Stationaryandmovingdevicesneedtobeoperatedmanuallyandinautomatedmodefortreatmentofsurfaces with complex geometries and undercuts.

ScopeProjects aim to: • Developlargescalehighthroughputunitsbasedondifferentprocessingmethods(e.g.,sonochemical

processing, atmospheric plasma treatment) to produce graded nanocomposite surfaces (e.g. textile, ceramics, concrete, wood etc.) displaying durable functionalities.

• Develophand-toolstotreatsurfacesoffacades,curvedsurfacesofstone,ceramics,woodproducts.• Developnanocoatingswithdifferentpropertiesandfunctionalities(e.g.,protective,gasbarrier,moisture

barrier, transpiration, photoactive, self cleaning, surface depolluting). Target TRL 7Needed economical resources (public and private)NAExpectedImpact• Deploymentofnewprocessesonnanocoatingsdurabilityenhancementwillallowthebroadeningof

the application spectrum of plasma, powder coating and sonochemical processing methods, presently used in a limited number of applications due to investment cost, reproducibility limitations and need of dedicated environments.

SuggestionsonTypeofAction RIA

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Code Title of the actionVC2-L-003 Networkingandcoordinationactivitiestopromotecertificationof

rawnanomaterialsthoughoutthewholemanufacturechainintheproductionofwaterandairpurificationsystem

Timeline >2022Product Classes IdentifiedGapsP2-2:Photocatalysisforwaterand indoor and outdoor air pu-rification

• Lackofknowledgetransfernetwork• ISOstandardization

P2-3: Nanostructured surfaces with increasedselectivityto-wardstracecontaminantsforwatermanagement

• Lackofknowledgetransfernetwork• ISOstandardization

SpecificChallengeNAScopeNATarget TRL NANeeded economical resources (public and private)NAExpectedImpactNASuggestionsonTypeofAction CSA

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Code Title of the actionVC2-L-004 Smarthandlinginteractionsofparts/componentswithsensitive

nano-enabled surfacesTimeline >2022Product Classes IdentifiedGapsNA NASpecificChallengeNAScopeThe proposed projects should address:• Novelwaystoreducedetrimentalhandlinginteractionswithsensitivenano-scaledstructures(e.g.,by

fluidbasedhandling).• Continuousconditionmonitoringofpotentiallydetrimentalinfluencesandinlineclosedloopcontrolof

process parameters. Target TRL NANeeded economical resources (public and private)NAExpectedImpactNASuggestionsonTypeofAction RIA

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8 Appendix III

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8 Appendix III

AppendixIII-VC3 - Manufacturing of powders made of functional alloys, ceramics and intermetallics

Actions Description Fiches

ThisappendixcontainsoneactionficheforeachVC3action,whichincludes,whenapplicable,ac-tioncode,title,timeline,productclassesandgaps,specificchallenges(i.e.theneedfortheaction),scope (i.e. the list of objectives), TRL expected, needed economical resources (i.e. the suggested economic size of the projects), impact (i.e. the expected social and economic outcome) and type ofaction.IftheactionhassynergieswithtopicsidentifiedintheNANOfutures Integrated Research and Industrial Roadmap for European Nanotechnology (available at http://www.nanofutures.eu/documents), reference to the Nf topic codes is presented.

Code Title of the actionVC3-S-001 Modellingtoolsformicrofluidicbehaviorofnanoparticlesand/or

advancedfluidsTimeline 2015-2018Product Classes IdentifiedGapsP3-6:Smallindividualnanopar-ticles <5nm

• Modellingofmaterialpropertiesfocusedonconvincingtheinvestors• Estimatinglifetimeandcosts• Designforproperties• ThermalStabilityofNanoparticlesintheprocesses(modellingis

required)P3-7: Fluids • Stablenanosysteminlifecycle:aggregatesandmatrices

• ThermalStabilityofNanoparticlesintheprocesses(modellingisrequired)

SpecificChallengeThebehaviouroffluidsatthemicroscalecandifferfrommacrofluidicbehaviourinthatfactorssuchassur-facetension,energydissipation,andfluidicresistancestarttodominatethesystem.Microfluidicsstudieshow these behaviours change, and how they can be worked around, or exploited for new uses. At nano scales some interesting and sometimes unintuitive properties appear. In particular, the Reynolds number canbecomeverylow.Akeyconsequenceofthisisthatfluids,whenside-by-side,donotnecessarilymixinthetraditionalsense;moleculartransportbetweenthemmustoftenbethroughdiffusion.Microfluidicstructuresincludemicro-pneumaticsystems,i.e.microsystemsforthehandlingofoff-chipfluids(liquidpumps,gasvalves,etc.),andmicrofluidicstructuresfortheon-chiphandlingofnano-andpicolitrevolumes.ScopeDemo targeted collaborative projects will be focused on modelling emerging application areas for biochips likeclinicalpathology,especiallytheimmediatepoint-of-carediagnosisofdiseasesormicrofluidics-baseddevices, capable of continuous sampling and real-time testing of air/water samples for biochemical toxins and other dangerous pathogens. Target TRL 5-6Needed economical resources (public and private)NA

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ExpectedImpact• Rapiddeploymentofadvanceddevicesandsolutionsthroughpredictivedesignofmicrofluidicsbehavior

forspecifiedapplications• Definitionofguidelinesandreferencecasesthatcontributetothediffusionandadoptionofthemicro-

fluidictechnology• AcceleratedintroductionofnewmicrofluidicdevicesinEUandinternationalmarketSuggestionsonTypeofAction RIAReferencewithNfproposedactions

VC5-S-013

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Code Title of the actionVC3-S-002 Costeffectiveindustrialscaletechnologiesforfillersynthesisand

technologies for dispersionTimeline 2015-2018Product Classes IdentifiedGapsP3-1:Nano-oxidesandNanoceramic

• Compatibilitywithprocessstep• Blendingandmixingindifferentmatrices

P3-3: Metal and Polymer com-posites

• Costissuesofmaterial(themarketputcostconstrains)• Marketpenetration,useofnewproductsolution• Blendingandmixingindifferentmatrices

P3-5: Catalyst and Nanodisper-sion

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Directlinktominingindustriesassourceofrawmaterialtoavoiduseless processing step

• Effectiveindustrialprocessestoscaleupnewproductsarisingfromlow Technology Readiness Level (lab scale - Spin off problem)

• AddresstoHandling,Health&Safetyconsiderationinordertosup-ply other Value Chains.

P3-7: Fluids • Effectiveindustrialprocessestoscaleupnewproductsarisingfromlow Technology Readiness Level (lab scale - Spin off problem)

• Pre-productionsuitabletohigh-volumemanufacturing(HVM),sup-port of initial phase is needed

• BlendingandmixingindifferentmatricesP3-8: Nanoporous system (met-al-organicframeworks)usedforcatalysis,gaspurification,safegasdelivery systems,nano-medicine,etc…)

• Industrialprocessestoscale-up

P3-9:Hybridnanopowders(Ce-ramicormetallicnanopowderscontaining functional groups (polymers,biomolecules)usedforapplicationsinelectronics,nanomedicine)

• AddresstoHandling,Health&Safetyconsiderationinordertosup-ply other Value Chains

SpecificChallengeDuring the last few years industrial scale production facilities for nanomaterials have been established by several manufacturers. The prices for industrial grade x-nanotubes or x-nano wires (x=C, Cu, Si, Ag, Pt,…) havereachedsuchalevel,thattheyhavebecomerealisticfunctionalfillerinpolymer(nano)compositesfor large volume productions. While trying to realize these nanocomposite materials the experience sug-geststhatforindustrialapplicationismuchmoredifficulttodisperseeveninlowviscositysolventsandthey react differently to grafting chemistry.New solution are required to allow an effective dispersion of the nanoparticles in slurries and pastestes ready to be diluted for industrial applications, facilitating handling and processing of the nano materials furtherwideningtheirapplicationfields.Suchtechnologiesbasedonwetmethodsnecessitateabet-ter understanding of relationship between process and materials, on reproducibility and reliability of the nanoparticles stabilisation and dispersion in the media in order to get a better interface control. These approaches could be applied for nanocomposites systems or end use application like the Chemical Me-chanical Polishing (CMP).ScopeTechnology improvements are required and demo targeted collaborative projects can be the proper funding scheme to study and develop new synthesis and dispersion processes and the technologies to produce thefinalcomponentbasedonthenewgenerationofnanocompositesAn important aspect is the development of a pilot line for scaling-up of the production. The projects are expected to yield innovative processes and equipments for a better manufacturing of nanocomposites.Selection of a processing technique and optimization of process parameters addressing proper dispersion and distribution of nano- particles or nano-particle aggregates within the matrixSafety considerations and contribution to standardization should be an integral part of the projects. Recy-cling aspect have to be considered from the design until the end use applications.

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Target TRL 5-6Needed economical resources (public and private)NAExpectedImpact• Significantimprovementsinindustrialproductivity,reliability,safetyandcostcompetitivenessincom-

parison with traditional processes;• Supplyoflowcost,highperformanceandenvironmentallyfriendlynanomaterialsdispersedinproper

matrix as master batches, allowing European manufacturers to exploit the great growth opportunity in thisfield;

• Addressthefullvaluechainpromotingclosercollaborationbetweenmaterialssuppliers,productionengineers, equipment manufacturers and end-users;

• Promotingsafe-by-designapproaches.SuggestionsonTypeofAction RIAReferencewithNfproposedactions (if any)

VC5-002-short and VC5-012-short.

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Code Title of the actionVC3-S-003 Reactive/InSitu/Inprocessgenerationofthenano-featuresas

largescale,lowcostsourceofnanomaterialsTimeline 2015-2018Product Classes IdentifiedGapsP3-1:Nano-oxidesandNanoceramic

• Compatibilitywithprocessstep• Newnetshapemanufactureofnanocompositeswithoutlosingthe

particles by agglomeration• Blendingandmixingindifferentmatrices• Newnetshapemanufactureofnanocompositeswithoutlosingthe

particles by agglomeration/ Nanoparticle dispersion is necessaryP3-2: Nano alloys • Costissuesofmaterial(themarketputcostconstrains)

• Top-Downproduction:Methodsforseparationandclassificationofparticles

• Stablenanosysteminlifecycle:aggregatesandmatrices• Refinementofexistingnanoparticles:• Top-Downproduction:Methodsfornanogrinding,separationand

classificationofparticlesP3-3: Metal and Polymer com-posites

• Costissuesofmaterial,themarketputcostconstrains• Top-Downproduction:Methodsforseparationandclassificationof

particles• Blendingandmixingindifferentmatrices• Novelproductionprocesses,processarchitecturerefinement• Top-Downproduction:Methodsfornanogrinding,separationand

classificationofparticlesP3-6:Smallindividualnanopar-ticles <5 nm

• Novelproductionprocesses,processarchitecturerefinement• Refinementofexistingnanoparticles:• Compatibilitywithprocessstep• Refinement/multi-functionalizationofexistingnanoparticles

P3-7: Fluids • Refinementofexistingnanoparticles:• Blendingandmixingindifferentmatrices• Effectiveindustrialprocessestoscaleupnewproductsarisingfrom

low Technology Readiness Level (lab scale - Spin off problem) • Marketpenetration,useofnewproductsolution• Blendingandmixingindifferentmatrices.Nanoparticledispersion

in different matricesP3-8: Nanoporous system (met-al-organicframeworks)usedforcatalysis,gaspurification,safegasdelivery systems,nano-medicine,etc.)

• Novelproductionprocesses,processarchitecturerefinement• Top-Downproduction:Methodsforseparationandclassificationof

particles• Blendingandmixingindifferentmatrices• Clearstandardsforsafetyandhandling• Top-Downproduction:Methodsfornanogrinding,separationand

classificationofparticlesP3-9:Hybridnanopowders(Ce-ramicormetallicnanopowderscontaining functional groups (polymers,biomolecules)usedforapplicationsinelectronics,nanomedicine)

• Blendingandmixingindifferentmatrices• Top-Downproduction:Methodsforseparationandclassificationof

particles• Novelproductionprocesses,processarchitecturerefinement• Top-Downproduction:Methodsfornanogrinding,separationand

classificationofparticles• AddresstoHandling,Health&Safetyconsiderationinordertosup-

ply other Value Chains.

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SpecificChallengeSuccessful adaptation of nanotechnology in the end-products requires in many cases to utilize material thatareabletodeveloptheirnano-functionalitiesduringthestandardprocessofproductandsemifinishedproduct manufacturing. As an examples plastics additives that crystallize in nanoparticle during injection moulding, metal phases that are formed during forging, or hieratic structures that spontaneously forms during application of a coating. The possibility to obtain the nano features directly during the manufactur-ing process strongly reduces the safety issues related to the use of free nanoparticles contributing to a safe utilization of nanomaterials. This manufacturing principle require a strong connection between all the actors in the production line and in particular between material producer and end-product manufacturer. Themainobjectiveofthisactionisofferingcustomfabricatedsemifinishedcomponentsfromadvancedmaterials, including nanofoams and nanocomposites obtained from the Reactive/In Situ /In process gen-eration of the nano-features.ScopeThereistheneedtodevelopanefficient,continuousmethodoflarge-scale,low-costsynthesisofsuchreactive materials. To answer to this need the following steps are suggested: 1) Include in the product in-novation the raw material sources, for example the mining industry to ensure the supply of the most critical materials; 2) ensure cooperation between material producer and end-product manufacturer; 3) development ofqualitycontrolandprocessverification(includingonlinemeasurements).4)assuresustainableandsafeproduction and use and end of life by state-of-the-art life-cycle analysis. 5) adress the aspect of reuse, recycling or disposal of the materials containing the developed nano features. Target TRL 6-7Needed economical resources (public and private)NAExpectedImpact• Demonstratedincreaseddegreeofcompatibilityofadvancedreactivematerialswithexistingproduc-

tion lines, leading to higher production volumes, improved reliability and repeatability of produced nano enabled product and lower production cost

• Promotingsafe-by-designapproaches• Acceleratedmarketuptakeofnanomaterialsandnano-enabledproducts• Improvementintechnicalknowledgeontheintegratedmanufacturingprocessesfornanomaterialsin

terms of productivity and cost-effectiveness • Definitionofguidelinesandreferencecasesthatcontributetodevelopmentofbusinessplansthaten-

courage private sector investment for future business growth SuggestionsonTypeofAction RIAReferencewithNfproposedactions (if any)

VC6-001-medium, VC6-004-medium and VC6-011-medium.

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Code Title of the actionVC3-M-001 Simulationsandproofofconceptsonmaterialsforenergystorage

(e.g. materials for natural gas storage)Timeline 2019-2022Product Classes IdentifiedGapsP3-4: Nanomaterials technology forsubstitutionofCriticalRawMaterials(NewNano-alloysandmetal-polymer nanocomposites canbeasolutionasnewsubsti-tutive alternative technology for Critical Materials substitution)

• Modellingofmaterialpropertiesfocusedonconvincingtheinvestors;on estimating lifetime and costs - design for properties

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

• Substitutionofrareearthmaterials(poorlyavailableforpolitical,geographical reasons)

P3-8: Nanoporous system (met-al-organicframeworks)usedforcatalysis,gaspurification,safegasdelivery systems,nano-medicine,etc…)

• Marketpenetration,useofnewproductsolution• Compatibilitywithprocessstep• Modellingofmaterialpropertiesfocusedonconvincingtheinvestors;

on estimating lifetime and costs - design for properties

SpecificChallenge• Novelnanomaterialsmustpermit/allowcontrollingthecatalyticprocessinquantityofgasorliquidphase

embedded and controlled release of the energy with accomplishment of the safety operation conditions• SubstitutionrareearthmaterialsScopeNanopowders and bulk materials with design properties (such as porosity, hydrophobicity and surface reactivity,controlledthermaltransferproperties)shouldbepreparedforstorageofspecificgases(e.g.natural gas, hydrogen) or liquids (e.g. phase change materials) with energy storage capabilities.Develop new materials (design, properties) Target TRL 5Needed economical resources (public and private)NAExpectedImpactThe new materialsphotocatalitic are facilitating materials with high energy capacity per volume enabling to create and expand new market niches for novel depolluting systems energy storage devices used in transport and seasonal thermal energy storage. SuggestionsonTypeofAction RIA

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Code Title of the actionVC3-M-002 DevelopmentofnewnanomaterialsassubstitutionsofCritical

RawMaterials(CRMs)Timeline 2019-2022Product Classes IdentifiedGapsP3-4: Nanomaterials technology forsubstitutionofCriticalRawMaterials(NewNano-alloysandmetal-polymer nanocomposites canbeasolutionasnewsubsti-tutive alternative technology for Critical Materials substitution)

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Novelproductionprocesses,processarchitecturerefinement• Marketpenetration,useofnewproductsolution• ThermalStabilityofNanoparticlesintheprocesses(modellingis

required)P3-5: Catalyst and Nanodisper-sion

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Selectionofmaterialsandsubstitutionofscarcematerialstoavoidindustrial dependence

• Processadaptationdownstreamfortheintroductionofnewmaterialsinto existing Value Chains

SpecificChallenge• Newmaterialscanbeproducedaftertestingandsimulation• Novelcompositionswithoutorreducedcriticalmaterialscontentmustbeobtainedstartingfromab-initio

modelling(tofindthebestreplacementsystem)andsimulationtofunctionaltestinganddemonstrationfordifferentfieldssuchaselectronics,opto-electronics,magnets,photonics,sensorsortransducers

• FindnanomaterialswithsimilarorevenbetterpropertiesasCRMs• Substitutionofscarcematerialstoavoiddependenceofothercountries/companiesScopeNew materials which substitute critical raw materials must be project to have technological properties in applications.Nanopowders,thinfilmsorthickcoatingswithsimilarorevenimprovedfunctionalproper-ties compared to actual materials but with reduced or no critical materials content must be designed and prepared for high tech applications. Actually many of this high tech applications use rare earth and other critical materialsSelf-sustainability in respect of CRMs Target TRL 5Needed economical resources (public and private)NAExpectedImpact• Newmaterialswithab-initodesignandtechnologiesforobtainingthinfilmsandcoatingsthatcanbe

easily implemented in high tevh applications without affecting the properties of materials actually used. Reduce the costs of raw materials and processing

• Economic,politicalimpacts• NatureimpactsSuggestionsonTypeofAction RIA

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Code Title of the actionVC3-L-001 Developingjointinterdisciplinaryexperimentalplatforms,includ-

ingvirtualplatforms,withopenaccesforSMEsTimeline >2022Product Classes IdentifiedGapsP3-1:Nano-oxidesandNanoceramic

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Workersneedstobetrainedintheuseofnewmaterialsandproduct

acceptance of steel with nano oxides (there are different methods of treating components in service)

• CompatibilitywithprocessstepP3-2: Nano alloys • Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Clearsafetyregulationbasedonpropertytest,notinsidestructures

-REACH complication• Compatibilitywithprocessstep

P3-3: Metal and Polymer com-posites

• Regional,NationalandTransnationalSupportforInnovativeClusters• Novelproductionprocesses,processarchitecturerefinement• Clearsafetyregulationbasedonpropertytest,notinsidestructures

-REACH complication• Excessofregulationcouldkillthemarket

P3-4: Nanomaterials technology forsubstitutionofCriticalRawMaterials(NewNano-alloysandmetal-polymer nanocomposites canbeasolutionasnewsubsti-tutive alternative technology for Critical Materials substitution)

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Regional,NationalandTransnationalSupportforInnovativeClus-ters

• Marketpenetration,useofnewproductsolution• Stablenanosysteminlifecycle:aggregatesandmatrices

SpecificChallenge• Elaboratemethodologies,protocolsandactionsenhancingcooperationbetweenSMEsandacademia

enablingfulldemonstrationofnanomaterialsforspecificSMEsapplication,withfullrespecttoIPRproblems

• Knowledgetransfer• IdentifymarketopportunitiesScope• Developmentofnovelnanomaterialsandgenerationofnewideasrequiredifferentcomplementarysyn-

thesis and characterisation methods for implementation in SMEs production lines. It is required enhanced collaboration by creating virtual platforms to speed up the transfer of knowledge and technologies along the whole value chain.

• NovelproductionprocessesTarget TRL 7Needed economical resources (public and private)NAExpectedImpactReduce the costs of experimental works by adequate utilisation of different complementary infrastructures by creating virtual platforms. Reduce time to market and increase the quality of products. Increasing SMEs market SuggestionsonTypeofAction IA

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Code Title of the actionVC3-L-002 Developmentofnewcomprehensivemethodsandmultiscale

modellingacrossfullvaluechainstodesignnewnano-relatedmaterials or to increase their TRL

Timeline >2022Product Classes IdentifiedGapsP3-4: Nanomaterials technology forsubstitutionofCriticalRawMaterials(NewNano-alloysandmetal-polymer nanocomposites canbeasolutionasnewsubsti-tutive alternative technology for Critical Materials substitution)

• Modellingofmaterialpropertiesfocusedonconvincingtheinvestors;on estimating lifetime and costs - design for properties

• Novelproductionprocesses,processarchitecturerefinement• ThermalStabilityofNanoparticlesintheprocesses(modellingis

required)

P3-5: Catalyst and Nanodisper-sion

• Processadaptationdownstreamfortheintroductionofnewmaterialsinto existing Value Chains

• Selectionofmaterialsandsubstitutionofscarcematerialstoavoidindustrial dependence

• Substitutionofrareearthmaterials(poorlyavailableforpolitical,geographical reasons)

P3-8: Nanoporous system (met-al-organicframeworks)usedforcatalysis,gaspurification,safegasdelivery systems,nano-medicine,etc…)

• Modellingofmaterialpropertiesfocusedonconvincingtheinvestors;on estimating lifetime and costs - design for properties

• ThermalStabilityofNanoparticlesintheprocesses(modellingisre-quired)

• Novelproductionprocesses,processarchitecturerefinementP3-9:Hybridnanopowders(Ce-ramicormetallicnanopowderscontaining functional groups (polymers,biomolecules)usedforapplicationsinelectronics,nanomedicine.)

• Modellingofmaterialpropertiesfocusedonconvincingtheinvestors;on estimating lifetime and costs - design for properties

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

SpecificChallenge• Increasingthehealthsafety• Materialsmodellingandprocessmodellingalongthewholelifecyclewillleadtonovelmaterialswith

controlled properties and reduce the health and environmental risks• Developnewmaterials/processestoavoidindustrialdependence• ProcessadaptationforthenewmaterialsScope• Developmentofnovelnanomaterialswithdesignpropertiesrequiresnewab-initomethodsformodel-

ling and simulation (e.g. molecular dynamics to predict interactions of nanomaterials and human cells) topredictfinalpropertiesinapplications.Differentothermathematicaltoolsformodellingprocesspa-rameters in different stages to optimize the materials development may be used to easily up-scale the materials processing while reducing the experiments usually required for validation.

• Usingmathematicaltoolsformodellingprocessparameterstooptimizethematerialsdevelopment.• NewproductionprocessesTarget TRL 7Needed economical resources (public and private)NAExpectedImpactReduce the cost of implementation.Materials with better properties by design and processes optimization will reduce the costs for implementa-tiontoTRL7andincreasetheinvestors’confidence.SuggestionsonTypeofAction RIA

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Code Title of the actionVC3-L-003 Synthesisof‘hosted’nanoparticlesystemsfornanomedicineTimeline >2022Product Classes IdentifiedGapsP3-6:Smallindividualnanopar-ticles <5nm

• Marketpenetration,useofnewproductsolution• ThermalStabilityofNanoparticlesintheprocesses(modellingis

required)• Stablenanosysteminlifecycle:aggregatesandmatrices• Compatibilitywithprocessstep

P3-9:Hybridnanopowders(Ce-ramicormetallicnanopowderscontaining functional groups (polymers,biomolecules)usedforapplicationsinelectronics,nanomedicine.)

• Compatibilitywithprocessstep• ThermalStabilityofNanoparticlesintheprocesses(modellingis

required)

SpecificChallengeHosted nanoparticles should be non-toxic for humans, easily processed, and selective to attach and release the active guest molecules. GMP for future pharmateutical products utilizing nanomaterials [WG-R&D]ScopeNanodispersion, nanoemulsions, denrimers should be prepared and combined with the active guest mol-ecules for nanomedicine needs. Development of nanostructured drug delivery systems. Toxicity assess-mentfornanomaterials.Strictspecificationsfornanomaterialsutilizedinbiomedicalapplications.Designof combined nanomaterials utilized in nanomedice [WG-R&D]Particles dispersion (critical step in nano)Target TRL 6-7Needed economical resources (public and private)NAExpectedImpactEnhance European competitiveness in Pharmaceutical Industry [WG-R&D]Reduce the time to market of novel systems for nanomedicine. Improve diagnosis capabilities, reduce risks for patient health and increase patients comfort in surgical applications. SuggestionsonTypeofAction RIA

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9 Appendix IV

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9 Appendix IV

AppendixIV-VC4 - Lightweight multifunctional materials and composites for transportation Actions Description Fiches

ThisappendixcontainsoneactionficheforeachVC4action,whichincludes,whenapplicable,ac-tioncode,title,timeline,productclassesandgaps,specificchallenges(i.e.theneedfortheaction),scope (i.e. the list of objectives), TRL expected, needed economical resources (i.e. the suggested economic size of the projects), impact (i.e. the expected social and economic outcome) and type ofaction.IftheactionhassynergieswithtopicsidentifiedintheNANOfutures Integrated Research and Industrial Roadmap for European Nanotechnology (available at http://www.nanofutures.eu/documents), reference to the Nf topic codes is presented.

Code Title of the actionVC4-S-001 Scoutingofenablingmanufacturingtechniquestoscaleupin-

novativeproductionsthroughtheIdentificationofbreakthroughmarketmodels

Timeline 2015-2018Product Classes IdentifiedGapsP4-1: Multifunctional materials withembeddedsensing/actua-tion functions (e.g. standard dashboardwithprintedelec-tronics)

• Reductionofproductioncosts• Multi-scalemodelling• Compatibilitywithexistingproductionlines

P4-2:Materialswithself-heal-ing/antiscratchproperties(e.g.bumperscompliantwithrecy-clingrequirements,UVprotec-tion etc.)

• Eco-design• Predictionofbehaviourinoperativeconditions• Multi-scalemodelling

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermal layer, thermoelectricmaterials for thermoelectric generators,etc.)

• Costofmaterialstostarttesting• Reductionofproductioncosts• Difficultiesinidentifyingmarketvolumes

P4-6:Lightweightmaterialsforengines (e.g. ceramic foams)

• Costofmaterialstostarttesting• Reductionofproductioncosts

P4-8: Multifunctional materials withembeddedelectronics(e.g.Quantum Dot LED for car dash-board)

• Costofprocessingunitstoscale-up

P4-9: Bio-based materials for sandwichpanels(e.g.nanocel-lulosebasedfoamsandfibres)

• Lackofindustriallyacceptabletechnologiesforparticularkindoffi-bres/particles

• Bio-baselightweightsustainablecomposites

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P4-10: Nanocomposite coatings providingfriction/wearreduc-tion for the energy sector (e.g. cylinder liners & piston rings)

• Costofprocessingunitstoscale-up

SpecificChallengeThefieldofadvancedmaterialshaswitnessedremarkableprogressesinthelastfewyearswiththeadventof innovative productions gathering multifunctional materials on market. As a major objective, the interest focused on development of new materials, components and products allowing compliance with respect precise requirements, and ensuring at the same time, cost effective and sustainable industrial scale produc-tions. In order to enable SMEs to enter this crucial stage of the research-development-innovation cycle, larger enterprises and/or research and technological organisations are asked to get together in order to provide reliable market driven models and to suggest the needed hints to promote the progress of incoming techniques since from the production stage.ScopeProject should promote the investigation of most advanced enterprises involved in production of advanced materials in order to point out major opportunities and threats related to trades around this sector on a European and Worldwide scale. The harvesting of such techniques may be extended across the entire value chain; from R&D to production and distribution to use and waste processing or recycling. All these factors should be addressed to the needs of SMEs active in this sector, in order to develop busi-nessmodelsandoutlinevaluableindustrialsolutionsaimedattheidentificationofaffordableindustrialstrategies. Proposals should address a range of industrial applications and involve a number of advanced materials producers, e.g. the actors involved in manufacturing of lightweight composites, smart advanced materials, nanomaterials, KETs, etc.. Moreover a business plan is expected in order to evaluate coopera-tionamongSMEsandtodefineeligiblenetworks,facilitiesidentifiedastangibleassetsandEUfinancialfunds to improve follow-up actions as an attempt of scale-up productions after the project. Target TRL NANeeded economical resources (public and private)NAExpectedImpact• ThedirectandsustainableimpactofthisactionwillbetoreducethegapbetweenSMEs,sciencere-

search around industrial advanced technologies for innovative materials and market requirements, in order to promote scale-up productions, compliant and aligned with global challenges;

• Identificationofadvancedautomatedproductionlines/processes,leadingtohigherproductionvolumes,improved reliability and repeatability of produced advanced materials and lower production cost; avail-abilityofneworsignificantlyimproved“fitforpurpose”toolsforintegrationinthoselines;

• ContributiontoenhanceSMEs’competitivenessbymeansofvaluablebusinessplansdrawingasamain outcome the hints needed for entering new markets and being competitive on a wide scale;

• ContributiontoachievingEUpoliciesinviewoffundingdeploymentsinsupportofSMEsaddressedinthe project.

SuggestionsonTypeofAction CSAReferencewithNfproposedactions

NT7-medium

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Code Title of the actionVC4-S-002 DevelopmentofhybridLCA/LCCandFEmodellingtechniquesfor

smartlightweightcompositesTimeline 2015-2018Product Classes IdentifiedGapsP4-1: Multifunctional materials withembeddedsensing/actua-tion functions (e.g. standard dashboardwithprintedelec-tronics)

• Cco-design• LCA(Characterizationfactorfortoxicitycategories)

P4-2:Materialswithself-heal-ing/antiscratchproperties(e.g.bumperscompliantwithrecy-clingrequirements,UVprotec-tion etc.)

• Costofmaterialstostarttesting• Abilitytoprovidedatabaseofproperties• Characterofmaterialsinoperativeconditions

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermal layer, thermoelectricmaterials for thermoelectric generators,etc.)

• Potentiallackofproduct/performancespecificationsandcharacteri-zation methods

• InventorydataforLCAtoolsonindustrialproductionofnanoproductsand end of life

P4-6:Lightweightmaterialsforengines (e.g. ceramic foams)

• InventorydataforLCAtoolsonindustrialproductionofnanoproductsand end of life

P4-11:Bulknanocompositesforheatrecovery(e.g.forexhaustsystems)

• Characterofmaterialsinoperativeconditions• Endoflife• InventorydataforLCAtoolsonindustrialproductionofnanoproducts

and end of lifeP4-12: Nanocomposite based fuels/nanocompositeadditiveswithenhancedchemicaltother-mal energy conversion proper-ties

• Buildingofknowledge• Predictionofbehaviourinoperativeconditions• LifeCycleAnalysisandLifeCycleCostAnalysismodelsforNANO• LCA(Characterizationfactorfortoxicitycategories)

P4-13:Lowviscosityoils(nano-fluids)

• LifeCycleAnalysisandLifeCycleCostAnalysismodelsforNANO• Toxicityofnanomaterials• InventorydataforLCAtoolsonindustrialproductionofnanoproducts

and end of lifeP4-14:Materialswithnanostruc-tured surfaces (e.g. for friction reduction obtained by nano-printing and nanopatterning techniques)

• LifeCycleAnalysisandLifeCycleCostAnalysismodelsforNANO• LCA(Characterizationfactorfortoxicitycategories)• SafetyofNANOproducts• Toxicityofnanomaterials

SpecificChallengeAdvanced lightweight composites are expected to improve technologies already existing on market and assure sustainable and affordable low-carbon based manufacturing processes needed for production. The industrial interest relies on advanced techniques able to improve modelling capacities by means of advanced assessments on environmental requirements and recognised European standards. A more ef-ficientproductionmethodmeansnotonlymaterialsolutionswithsensiblyreducedequivalentCO2impacts,otherwise a key node for global competitiveness due to related savings. The next future of proof-of-concept strategies requires strong modelling capacities, coupling both traditional Finite Element modelling (FEM) techniques and Lyfe Cycle Assessment (LCA) / Life Cycle Costs (LCC) methodologies in order to account these as valuable trade-off parameters while designing an innovative concept for lightweight composites

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ScopeProposals should evaluate the main factors directly involved into the entire life cycle of a prototype. This would allow to gather effects due to internal aspects, mainly addressed to design optimization require-ments, and external ones, referred to the environmental issues beyond the related production processes.The perfect understanding of factors beyond the ones directly impacting on material manufacturing pro-cesses may reveal strongly money driven because of indirect costs for assembling, usage, transporting (amongprovidersthroughoutthevaluechainorfromproviderstocustomers)andfinallydismantling.Nowadays the standard FE modelling techniques are strictly focused on technical issues without considering as a major aim the aspects connected to the innovation breakthrough on market. The LCA/LCC analysis as well allow to deepen design for environment techniques, even if the optimization does not affect the theoretical design behind the realization of a given prototype.Thescopeoftheworkistodefineamixedandintegratedapproachabletoconnectthemodellingoptimi-zation as a direct consequence of LCA & LCC results as well, apart from the technical requirements to be taken into account for realization.Proposals should contain a series of models for validation, in which previous models optimized on the base of only FE requirements, have to be improved by means of mixed requirements coming from LCA/LCC criteria. The results obtained following this new approach are compared with the former in order to point out advantages in using a mixed approach of analysis. The extended model should be implemented as a code integrated in a multi-features approach available to end-users. As part of each project, industrial end-usersshouldassessthiscodeonpredefinedindustrialtestcases,toguaranteeindustrialrelevance.Activities expected to focus on Technology Readiness Level 3-4. Target TRL 5-6Needed economical resources (public and private)NAExpectedImpact• Improvementincompetitivenessbyevaluatingallprocessesamongtheproof-of-conceptandthelaunch

on market phases and leading to a reduction of the capital (CAPEX) and/or operating (OPEX) expen-ditures;

• Rapiddeploymentoflower-costadvancedmaterialssolutionsthroughpredictivedesignofnovelmateri-als and production routes optimized by means of mixed methods for environmental and life-time costs assessment;

• Moreaffordableandsustainablematerials,componentsandproducts.SuggestionsonTypeofAction RIAReferencewithNfproposedactions

VC1-016-medium.

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Code Title of the actionVC4-S-003 LayeredCompositesMaterialbasedonfoam,functionalnanolay-

ers,andnewjoiningtechnologiesasenergysavingsolutionsTimeline 2015-2018Product Classes IdentifiedGapsP4-1: Multifunctional materials withembeddedsensing/actua-tion functions (e.g. standard dashboardwithprintedelec-tronics)

• Buildingofknowledge• IntellectualPropertyRightsprotection(costandtimeforprotection)• Abilitytoprovidedatabaseofproperties• Joiningdifferentmaterials

P4-5:Lightweightbatteriesin-cludingtheirpackaging(e.g.for electrical vehicles or vehi-cleswithhighelectricalstorageneeds)

• Costfordisassembly• Joiningdifferentmaterials• Compatibilityofexistingsafetyevaluationprotocolswithnanomateri-

als (generally developed for micro, risk of false conclusions)• Costfordisassemblyandeasinesstorecyclethematerials

P4-9: Bio-based materials for sandwichpanels(e.g.nanocel-lulosebasedfoamsandfibres)

• Lackofindustriallyacceptabletechnologiesforparticularkindoffibres/particles

• Characterofmaterialsinoperativeconditions• Safeprotocolsindifferentproductionsteps

P4-10: Nanocomposite coatings providingfriction/wearreduc-tion for the energy sector (e.g. cylinder liners & piston rings)

• Potentiallackofproduct/performancespecificationsandcharacteri-zation methods

• IntellectualPropertyRightsprotection(costandtimeforprotection)• Costofprocessingunitstoscale-up• Potentialreluctanceforuseofnanoinindustrydependingongeo-

graphical positionP4-11:Bulknanocompositesforheatrecovery(e.g.forexhaustsystems)

• Compatibilitywithexistingproductionlines• Characterofmaterialsinoperativeconditions

P4-14:Materialswithnanostruc-tured surfaces (e.g. for friction reduction obtained by nano-printing and nanopatterning techniques)

• Buildingofknowledge• Costofmaterialstostarttesting• Predictionofbehaviourinoperativeconditions• Characterofmaterialsinoperativeconditions• Costandsafetyofmaterialstostarttesting

P4-15: Metal-Organic Frame-works(MOFs):Versatilenano-porous materials (nanoMOFs and nanocrystals) Metal-organ-icframeworks(MOFs)representanewclassofhybridorganicinorganic supramolecular ma-terials comprised of ordered networksformedfromorganicelectron donor linkers andmetalcations.Theycanexhibitextremelyhighsurfaceareas,aswell as tunableporesizeandfunctionality,andcanactas hosts for a variety of guest molecules.Sincetheirdiscov-ery,MOFshaveenjoyedexten-siveexploration,withapplica-tions ranging from gas storage to drug delivery to sensing

• Buildingofknowledge• Predictionofbehaviourinoperativeconditions• Characterofmaterialsinoperativeconditions• Toxicityofnanomaterials

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SpecificChallengeLayer composites like sandwich panels are a growing market due to their effective combination of mechani-calpropertiesandlightweight,thesepropertiesleadstoefficientmaterialuseandenergysavingproduct.Sandwiched metallic foams are a typically example, they retain some physical properties of their base material.Foammadefromnon-flammablemetalwillremainnon-flammableandthefoamisgenerallyre-cyclable back to its base material. The main goal of the use of metallic foams for example in vehicles is to increase sound dampening, reduce the weight of the automobile, and increase energy absorption in case ofcrashes,foamfilledtubescanbeusedasanti-intrusionbarsreducingcarweightandsavingenergybydecreasing fuel consumption. Woods, plastics, ceramics and other materials can be used to obtain layered compositesandallofthemneedsspecifictechnologiestoenhancelayerinterfacestrength.ScopeNew methodologies for foams production and joining technologies should be designed and developed. Multi(nano)layering lamination processes, metal etching, assembling and gluing shall be studied through collaborative research projects which involve manufacturers and R&D high specialized centres. Target TRL 5-6Needed economical resources (public and private)NAExpectedImpact• Decreaseintheconsumptionofhighcostandcriticalmaterials.• Improvementoftheproductperformance,withoutincreasingthefinalprice.•reductionoftheoverall

environmental impact of developed applications, taking into account the phases of production, use and end of life

• StrengtheningofthecompetitivenessoftheEuropeanconstructionsectorinthefield• Newmarketopportunitiesthroughintroductionofnovelprocessinexistingproductionlines

SuggestionsonTypeofAction RIAReferencewithNfproposedactions

VC1-011-short and VC1-013-medium.

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Code Title of the actionVC4-S-004 CompositeorHybridMultifunctionalMaterialsandSystemsTimeline 2015-2018Product Classes IdentifiedGapsP4-1: Multifunctional materials withembeddedsensing/actua-tion functions (e.g. standard dashboardwithprintedelec-tronics)

• IntellectualPropertyRightsprotection(costandtimeforprotection)• Abilitytoprovidedatabaseofproperties• Joiningdifferentmaterials

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermal layer, thermoelectricmaterials for thermoelectric generators,etc.)

• Potentiallackofproduct/performancespecificationsandcharacteri-zation methods

• Reductionofproductioncosts

P4-8: Multifunctional materials withembeddedelectronics(e.g.Quantum Dot LED for car dash-board)

• Costofprocessingunitstoscale-up• Poorindustrialinterestintakingthedevelopingcost-risk

P4-9: Bio-based materials for sandwichpanels(e.g.nanocel-lulosebasedfoamsandfibres)

• Lackofindustriallyacceptabletechnologiesforparticularkindoffibres/particles

• Bio-baselightweightsustainablecompositesP4-12: Nanocomposite based fuels/nanocompositeadditiveswithenhancedchemicaltother-mal energy conversion proper-ties

• Certificationcosts• SafetyofNANOproducts• Toxicityofnanomaterials• UncertaintyofregulationforNANO

P4-14:Materialswithnanostruc-tured surfaces (e.g. for friction reduction obtained by nano-printing and nanopatterning techniques)

• Buildingofknowledge• Characterofmaterialsinoperativeconditions

SpecificChallengeThe future of engineering materials is to manufacture multifunction for Performance-Tailored products. Multifunctional materials are typically a composite or hybrid of several distinct material phases in which each phase performs a different but necessary function such a structure, packaging, transport, logic, and energy storage.As examples:• Textilenanofibrescouldbeefficientlyexploitedinthismarketsectorbydevelopingmultifunctionalnano-

composites not only exhibit excellent mechanical properties, but also display outstanding combination of optical, electrical, thermal, magnetic and other physic-chemical properties.

• Inautomotiveindustrythekeydriversfortheuseofpolymernanocomposite-enabledpartsintheauto-motiveindustryarereductioninvehicle’sweight,improvedengineefficiency(fuelsaving),reductioninCO2 emissions and superior performance (greater safety, increased comfort and better driveability).

ScopeThe achievement of two phase multifunctional systems show the promise of true materials integration; however, the combination of three or more functions including logic, sensing, energy storage, structure, and actuation will be required to achieve truly smart material systems, ultimately analogous to biological systems. However, there are still many limitations and challenges for nanocomposites production that needs to be tackled, these include: Consistency and reliability in volume production to a great extent, High lead time for commercialization that could take a longer time.The addressed sectors are Packaging/ Transportation/ Construction & Building this non-exhaustive list does not preclude other sectors. Target TRL 5-6Needed economical resources (public and private)NA

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ExpectedImpact• Definitionofguidelinesandreferencecasesthatcontributetodevelopmentofbusinessplansthaten-

courage private sector investment for future business growth• Enablingofinvestmentdecisionsformarketintroductionofnovel,cost-effective,safeandsustainable

nano-enabled products that demonstrate superior performance in terms of multifunctionality and sustain-ability

• Demonstratedscaling-upandincreaseddegreeofautomationofmultifunctionalmaterialproductionlines/processes, leading to higher production volumes, improved reliability and repeatability of produced multifunctional materials and lower production cost;

• Contributiontoimprovedresourceefficiency,safetyandenvironmentalfriendlinessofadoptionofthemultifunctional materials and related products (e.g. aiming at fully recyclable products);

• Promotingsafe-by-designapproaches‘Inlinequalitycontrolofproductpropertiestechniquesforvolu-metric multi scale characterization of nanocomposites

SuggestionsonTypeofAction RIAReferencewithNfproposedactions

VC1-007-medium and VC1-010-medium.

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Code Title of the actionVC4-M-001 IntegratedEuropeanweb-basedPlatformforadvancedcomposite

materialsprocessing,characterizationandstandards(JRC-like)Timeline 2019-2022Product Classes IdentifiedGapsP4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermal layer, thermoelectricmaterials for thermoelectric generators,etc.)

• Potentiallackofproduct/performancespecificationsandcharacteri-zation methods

• Certificationcosts• Fireresistancecompliancewithstandards• Regional/nationalguidelinesfornano-containingproductdisposal

and/or treatment

P4-5:Lightweightbatteriesin-cludingtheirpackaging(e.g.for electrical vehicles or vehi-cleswithhighelectricalstorageneeds)

• Highstrategicinterestsandrestrictedinformation• Certificationofcomponents• Compatibilityofexistingsafetyevaluationprotocolswithnanomateri-

als (generally developed for micro, risk of false conclusions)• Fireresistancecompliancewithstandards

P4-7:Materialswithanticorro-sionproperties(e.g.tanksfortransportation of UREA or for fuel distribution)

• Certificationofcomponents

P4-9: Bio-based materials for sandwichpanels(e.g.nanocel-lulosebasedfoamsandfibres)

• Fireresistancecompliancewithstandards• Bio-baselightweightsustainablecomposites

P4-11:Bulknanocompositesforheatrecovery(e.g.forexhaustsystems)

• Safeprotocolsindifferentproductionsteps

P4-14:Materialswithnanostruc-tured surfaces (e.g. for friction reduction obtained by nano-printing and nanopatterning techniques)

• Safetyofnanoproducts• Toxicityofnanomaterials• Abilitytopredictthedevelopmentofan“article”impactontheCO2

growth

SpecificChallengeQualitative data should also be included (e.g. colour or deformability for textile products). Suitability of materials for a prediction case. Data reliability.ScopeState of the Art for materials categorization is required in order to identify key/aspects like for example: functional properties, costs for development, environmental sustainability (health, toxicology, EoL). Forth-comingprojectsshouldaddressmaterialswithcustomizedproperties,e.g.enhancedconductivity,fireresistance, atc.Broad scope needs more focusing. Maintenance of the platform and the business, model should be pro-vided. Highlight of relevant gaps in standards or characterization tool. Target TRL NANeeded economical resources (public and private)NAExpectedImpact• Livingtools:anadministrationboardshouldbeinchargeofdatacheckingandvalidation.Validation

should be done by an indipendent body.• LinkwithVAMAS.• Methodologyandequipmentforcharacterizationofmaterialsathightemperaturesorharshconditions.• Linkwithrelevantbodiesandnormalization.SuggestionsonTypeofAction CSA

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Code Title of the actionVC4-M-002 Innovative manufacturing equipments for advanced nano-inte-

grated materials (e.g. on-line characterization controls and oper-tational standards compliance evaluation)

Timeline 2019-2022Product Classes IdentifiedGapsP4-1: Multifunctional materials withembeddedsensing/actua-tion functions (e.g. standard dashboardwithprintedelec-tronics)

• Multi-scalemodelling• Compatibilitywithexistingproductionlines• Characterofmaterialsinoperativeconditions• Joiningdifferentmaterials

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermal layer, thermoelectricmaterials for thermoelectric generators,etc.)

• Costofmaterialstostarttesting• Difficultiesinidentifyingmarketvolumes

P4-5:Lightweightbatteriesin-cludingtheirpackaging(e.g.for electrical vehicles or vehi-cleswithhighelectricalstorageneeds)

• Compatibilityofexistingsafetyevaluationprotocolswithnanomateri-als (generally developed for micro, risk of false conclusions)

• Certificationofcomponents

P4-6:Lightweightmaterialsforengines (e.g. ceramic foams)

• LackofEUfundedconcertedactiontoimprovecollaborationbe-tween R&D

• Poorindustrialinterestintakingthedevelopingcost-riskP4-9: Bio-based materials for sandwichpanels(e.g.nanocel-lulosebasedfoamsandfibres)

• Lackofindustriallyacceptabletechnologiesforparticularkindoffibres/particles

• FireresistancecompliancewithstandardsP4-11:Bulknanocompositesforheatrecovery(e.g.forexhaustsystems)

• Compatibilitywithexistingproductionlines• Safetyofnanoproducts• Uncertaintyofregulationfornano

P4-14:Materialswithnanostruc-tured surfaces (e.g. for friction reduction obtained by nano-printing and nanopatterning techniques)

• Predictionofbehaviourinoperativeconditions• Safetyofnanoproducts• Toxicityofnanomaterials

SpecificChallenge• Reliableandcost-effectivecharacterizationunits• NDEon-linecharacterization• Surfacecharacterization• Thresholdassessment• Decreaseofvehicleandaircraftweightdeterminesatremendousreductionoffuelconsumptionin

several operation regimes. The application of enhanced lightweight materials for interiors, complying withthefunctionalrequirementsandsafetystandardswillpromotemeanoftransportoverallefficiencyenhancement. Scalability of processing routes and processes hybridisation is the target to be achieved in order to transfer nanotechnology know how for implementation of industrial processes.

Scope• StateoftheArtonpilotlines,technologies,controlalgorithms,processmodellingtechniques• Thickcoatingcharacterization:controlofthicknessduringproduction(feedbackforprocesscontrol)• Packagingfilms:on-linecharacterization• SelectionofBATsandimplementationofscalablecosteffectiveprocessingroutestoinducefireresistant

property in conventional materials will respond to the criteria of cost effectiveness, sustainability and industrial implementation. Processes hybridisation provides a way to harmonize new nano-technology based solutions with conventional processing to attain equivalent or better functionalities by reducing amount of active agents and by decreasing the weight of products.

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Target TRL 7-8Needed economical resources (public and private)NAExpectedImpact• Multiscale• Operativeconditions• Joiningdifferentmaterials• Validationofproperties• 3Dtechniquesforqualitycontrolsofmanufacturing• Standardsfor3Dcharacterization• Enhancesustainabilityandsafetyoftransportsector• ReducefuelconsumptionandGlobalWarmingPotential• EnhancecompetitivenessofEuropeantextileandleatherindustry• SupporthightechSMEsastechnologyprovidersfornanotechnologybasedprocessing• Improveskillsandcompetitivenessofworkersinthefieldofmaterialindustrialtreatments• ReduceenvironmentalandsocialcostfortransportSuggestionsonTypeofAction RIA

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Code Title of the actionVC4-M-003 Advancedtechniquesforexperimentalassessmentofnano-ma-

terials propertiesTimeline 2019-2022Product Classes IdentifiedGapsP4-3: Fire resistant materials (e.g.covermaterial, suchasleatherandtextiles,forinteri-orscompliantwithstandardsfor homologation)

• Certificationofcomponents• Toxicityofnanomaterials• Negativeopinionsofpublicaudienceregardingnano(nanoisdan-

gerous)• Regional/nationalguidelinesfornano-containingproductdisposal

and/or treatmentP4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermal layer, thermoelectricmaterials for thermoelectric generators,etc.)

• Potentiallackofproduct/performancespecificationsandcharacteri-zation methods

• Certificationcosts• Uncertaintyofregulationfornano• Regional/nationalguidelinesfornano-containingproductdisposal

and/or treatment

P4-6:Lightweightmaterialsforengines (e.g. ceramic foams)

• Certificationofcomponents• Compatibilityofexistingsafetyevaluationprotocolswithnanomateri-

als (generally developed for micro, risk of false conclusions)• Regional/nationalguidelinesfornano-containingproductdisposal

and/or treatmentP4-7:Materialswithanticorro-sionproperties(e.g.tanksfortransportation of UREA or for fuel distribution)

• Certificationofcomponents

P4-10: Nanocomposite coatings providingfriction/wearreduc-tion for the energy sector (e.g. cylinder liners & piston rings)

• Potentiallackofproduct/performancespecificationsandcharacteri-zation methods

• Poorindustrialinterestintakingthedevelopingcost-risk• Certificationcosts

P4-11:Bulknanocompositesforheatrecovery(e.g.forexhaustsystems)

• Characterofmaterialsinoperativeconditions• Safetyofnanoproducts• Uncertaintyofregulationfornano• Toxicityofnanomaterials

P4-13:Lowviscosityoils(nano-fluids)

• Toxicityofnanomaterials

P4-14:Materialswithnanostruc-tured surfaces (e.g. for friction re-duction obtained by nanoprinting and nanopatterning techniques)

• Safetyofnanoproducts• Toxicityofnanomaterials

SpecificChallengeEstablishment of Regulations from EU for existing and forthcoming Production Lines (i.e Occupational Health & Safety Regulations)ScopeBuild interdiciplinary consortia in order to develop standardization protocols for nanomaterial characteriza-tion; Design of New Production Lines utilizing nanomaterials. Materals for thermo-electric generators. The objectisrelatedtonano-modifiedmaterials(nano-structured/nao-filled-materials).Target TRL 3-6Needed economical resources (public and private)NA

ExpectedImpactSustainable Development of Nanotechnology Sector in EU SuggestionsonTypeofAction RIA

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Code Title of the actionVC4-L-001 Integrationamongindustrialandresearchknow-howTimeline >2022Product Classes IdentifiedGapsP4-6:Lightweightmaterialsforengines (e.g. ceramic foams)

• LackofEUfundedconcertedactiontoimprovecollaborationbe-tween R&D

P4-10: Nanocomposite coatings providingfriction/wearreduc-tion for the energy sector (e.g. cylinder liners & piston rings)

• Cultureof(open)innovation

P4-12: Nanocomposite based fuels/nanocompositeadditiveswithenhancedchemicaltother-mal energy conversion proper-ties

• Highstrategicinterestsandrestrictedinformation• Howtoapproachtonano

P4-13:Lowviscosityoils(nano-fluids)

• Highstrategicinterestsandrestrictedinformation

SpecificChallenge• IndicatetoIndustryofchallengesthroughnanomaterialsutilization.• DesignoftechniqueswherenanomaterialscanbeintroducedinexistingProductionLines.• EstablishmentofRegulationsfromEUforexistingandforthcomingProductionLines(i.eOccupational

Health & Safety Regulations)Scope• WillassistthecooperationofdifferentengineeringandIndustrialSectors.• WillassistinthedesignofnewProductionLinesthatutilizenanomaterials.Designoftechniqueswhere

nanomaterials can be introduced in existing Production Lines. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactSustainable Development of Nanotechnology Sector in EU. SuggestionsonTypeofAction CSA

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Code Title of the actionVC4-L-002 Encourage stronger industrial environment of cooperation and

culture of fundings for development of forthcoming technologiesTimeline >2022Product Classes IdentifiedGapsP4-1: Multifunctional materials withembeddedsensing/actua-tion functions (e.g. standard dashboardwithprintedelec-tronics)

• Buildingofknowledge• Communicationbetweenindustryandacademia

P4-2:Materialswithself-heal-ing/antiscratchproperties(e.g.bumperscompliantwithrecy-clingrequirements,UVprotec-tion etc.)

• Buildingofknowledge• Poorindustrialinterestintakingthedevelopingcost-risk

P4-3: Fire resistant materials (e.g.covermaterial, suchasleatherandtextiles,forinteri-orscompliantwithstandardsfor homologation)

• Fireresistancecompliancewithstandards

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermal layer, thermoelectricmaterials for thermoelectric generators,etc.)

• Buildingofknowledge• Regional/nationalguidelinesfornano-containingproductdisposal

and/or treatment

P4-5:Lightweightbatteriesin-cludingtheirpackaging(e.g.for electrical vehicles or vehi-cleswithhighelectricalstorageneeds)

• Compatibilityofexistingsafetyevaluationprotocolswithnanomateri-als (generally developed for micro, risk of false conclusions)

P4-6:Lightweightmaterialsforengines (e.g. ceramic foams)

• Buildingofknowledge• LackofEUfundedconcertedactiontoimprovecollaborationbe-

tween R&D• Abilitytoprovideguidelinesonhowtoprocessnano-containing

products /Technical training• Regional/nationalguidelinesfornano-containingproductdisposal

and/or treatmentP4-8: Multifunctional materials withembeddedelectronics(e.g.Quantum Dot LED for car dash-board)

• Abilitytoprovideguidelinesonhowtoprocessnano-containingproducts /Technical training

• Communicationbetweenindustryandacademia

P4-10: Nanocomposite coatings providingfriction/wearreduc-tion for the energy sector (e.g. cylinder liners & piston rings)

• Potentiallackofproduct/performancespecificationsandcharacteri-zation methods

• Potentialreluctanceforuseofnanoinindustrydependingongeo-graphical position

• Cultureof(open)innovationP4-12: Nanocomposite based fuels/nanocompositeadditiveswithenhancedchemicaltother-mal energy conversion proper-ties

• Buildingofknowledge• Highstrategicinterestsandrestrictedinformation• Negativeopinionsofpublicaudienceregardingnano(nanoisdan-

gerous)• Uncertaintyofregulationfornano

P4-13:Lowviscosityoils(nano-fluids)

• Buildingofknowledge• Highstrategicinterestsandrestrictedinformation

P4-14:Materialswithnanostruc-tured surfaces (e.g. for friction reduction obtained by nano-printing and nanopatterning techniques)

• Buildingofknowledge

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SpecificChallenge• IndicatetoIndustryofchallengesthroughnanomaterialsutilization.• DesignoftechniqueswherenanomaterialscanbeintroducedinexistingProductionLines.Scope• WillassistthecooperationofdifferentengineeringandIndustrialSectors.• WillassistinthedesignofnewProductionLinesthatUtilizenanomaterials.Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactSustainable Development of Nanotechnology Sector in EU. SuggestionsonTypeofAction CSA

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10 Appendix V

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10 Appendix V

AppendixVNon-technicalActionsDescriptionFiches

Thisappendixcontainsoneactionficheforeachnon-technicalaction,whichincludes,whenap-plicable,actioncode,title,timeline,addressedValueChains,productclassesandgaps,specificchallenges (i.e. the need for the action), scope (i.e. the list of objectives), TRL expected, needed economical resources (i.e. the suggested economic size of the projects), impact (i.e. the expected socialandeconomicoutcome)andtypeofaction.Iftheactionhassynergieswithtopicsidentifiedin the NANOfutures Integrated Research and Industrial Roadmap for European Nanotechnology (available at http://www.nanofutures.eu/documents), reference to the Nf topic codes is presented.

Code Title of the actionNT-S-001 Networking,sharingbestpracticesandpromotingharmonised

methodologies such as standards or other authoritative guide-lines on managing nanomaterials and related products along their life cycle

Timeline 2015-2018Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• ISOstandardization• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

• Toxicityandphysic-chemicalcharacterizationassessmentpredictionin short and long term in the whole lifecycle

• Regional,NationalandTransnationalSupportforInnovativeClustersP2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• ISOstandardization• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Extremelydifficult,untilnow,toknowthepropertiesofmaterialsat

the nanoscale and, consequently, to know possible associated risks.P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Safeprotocolsindifferentproductionsteps• UncertaintyofregulationforNANO• Regional/nationalguidelinesfornano-containingproductdisposal

and/or treatment• InventorydataforLCAtoolsonindustrialproductionofnanoproducts

and end of lifeP1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Lackofstandards,lackofinfrastructure,organisationbody• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Clearsafetyregulationbasedonpropertytest,notinsidestructures-REACH complication

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P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Lackofstandards,lackofinfrastructure,organisationbody• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

P1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Lackofstandards,lackofinfrastructure,organizationbody

P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Lackofstandards,lackofinfrastructure,organisationbody• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Clearsafetyregulationbasedonpropertytest,notinsidestructures-REACH complication

P1-31:NonmainstreamMEMS • Lackofstandards,lackofinfrastructure,organisationbody• Toxicityassessmentpredictioninshortandlongterminthewhole

lifecycle• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

GAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• “Regional,NationalandTransnationalSupportforInnovativeClus-ters

• Improvethecommunicationchannelwithnationalindustriesas-sociations to share nanosafety parameters and standards”

• Clearsafetyregulationbasedonpropertytest,notinsidestructures-REACH complication

SpecificChallengeNovel nano-related materials are expected to play key roles for the promotion of innovations in the various industrial products. In order to make such novel nanomaterials to be socially acceptable and widely used, it is very important and necessary to establish and promote reliable standardized approaches for their safe and sustainable management. In fact, standardization is a technical solution to health and safety concerns thatcanpotentiallyprovidelegalcertaintyandconsumerconfidenceinnanotechnologyandnanomaterials.Standards are useful for the entire product life cycle. Standards have to be applied also on end of life solu-tions,toreduceatminimumtheimpactonenvironment(e.g.theEuropeanWasteCataloguehasspecificcodes,whichidentifiesparticularwastecategories).Thereisneedforgapanalysisonstandards,inordertofindstandardsusefulfortheindustries(e.gstandardsonnanopropertieskeyfortheapplications).ScopeThe main aim are:• Torevisepreviousworkonbestpracticeanalysis(e.g.NANOCOM,NANOreg,TTIPetc.)• TocollectfromEUindustries,researchcentres,consumerassociations,organisedcivilassociationsand

other stakeholdersto evaluate and disseminate previous and current best practices on the adoption of standards on managing nanomaterials and related products;

• Todevelopandpromoteaplanbetweenpolicymakersandstakeholdersinordertohaveasharedpointof view and proceed toward the standardization of nano enabled materials or products disposal with a cradle to crave approach.

• TostandardizeSafe-by-Designprocessandproductdevelopmentbasedonreal-lifescenariosTarget TRL NANeeded economical resources (public and private)NA

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Implementation Roadmap on value chains and related pilot lines 149

ExpectedImpact• StrengthenandextendthecurrentcooperationandcoordinationwithOECD,CEN,ISOandothersafety,

standardisation and regulation stakeholders (including key European funded projects in the nanosafety cluster).

• Strengthencollaborationbetweenacademiaandindustriesformanagementofnano-relatedproductsin a coordinated and standardized way.

• DevelopmentofastandardizationstrategyforSafe-by-Designonreal-lifescenariosascoordinatedefforts based on previous and ongoing Pilot-Line Projects

SuggestionsonTypeofAction CSAReferencewithNfproposedactions

NT11-short

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Code Title of the actionNT-S-002 Promotionofeffectivecommunicationonnano,fromdefinitionof

nanotonanolabellingandnano-relatedrisksandbenefitsTimeline 2015-2018Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• REACH• Workersneedstobetrainedintheuseofnewmaterialsandproduct

acceptance of steel with nano oxides (there are different methods of treating components in service)

• ClearstandardsforsafetyandhandlingP2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Safetyassessment/end-usersconsumers• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• NewRiskpreventionregulationforworkersadaptedtonewregula-tions - REACH. Particularly critical in SMEs and Spin-offs

• Marketpenetration,useofnewproductsolutionP4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Buildingofknowledge• Safetyofnanoproducts• Socialeducationandawarenessofthesocietyonthebenefitsof

newproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Workersneedstobetrainedintheuseofnewmaterialsandproductacceptance of steel with nano oxides (there are different methods of treating components in service)

• Clearstandardsforsafetyandhandling• Socialeducationandawarenessofthesocietyonthebenefitsof

newproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• NewRiskpreventionregulationforworkersadaptedtonewregula-tions - REACH. Particularly critical in SMEs and Spin-offs

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Marketpenetration,useofnewproductsolutionP1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Workersneedstobetrainedintheuseofnewmaterialsandproductacceptance of steel with nano oxides (there are different methods of treating components in service)

P1-31:NonmainstreamMEMS • NewRiskpreventionregulationforworkersadaptedtonewregula-tions - REACH. Particularly critical in SMEs and Spin-offs

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Marketpenetration,useofnewproductsolutionGAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Marketpenetration,useofnewproductsolution• Socialeducationandawarenessofthesocietyonthebenefitsof

newproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

• Clearstandardsforsafetyandhandling

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SpecificChallengeThe nomenclature for nanotechnology and nanomaterials needs to be developed so that regulators, stake-holders, and consumers can work with a common vocabulary and a common understanding of terms and their implications.Moreover, we need an active communication of “nano”-enabled value added features on as many value-adding products as possible. The consumers and decision makers need to learn that many products contain “nano”. Consumers will appreciate this open communication and they will be less fearsome of the word “nano” (though they may also get so used to nano that they no longer will consider to be some kind of magic solution but “just something.Access to information and some more transparency is needed to meet some of consumers’ concerns and contribute to build trust.Scope• Tostudypastefforts(ECpositions,projectsetc.)oncommunicationatnational,regionalandEuropean

level on nanolabelling, nomenclature etc.• Topromotediscussionandconsensusamongkeynomenclatureissuesregardingnanotechnology

through surveys and dedicated workshops.• Topromoteopencommunicationof“nano-specificrisks”,developingusecasesandpromotingbest

practices on actual products with detailed “lay term summary”.• Topromotetrainingandextendedguidanceforcompaniesonhowtobestcommunicateabouttherisks.• Tocommunicatewithtargetgroups(SMEs,consumers,citizens)onnanonomenclature,nanolabelling

and nano awareness in general. • TocollaboratewithECHAand/orotherinitiatives(e.g.Nanosafetycluster)inordertoodevelopclear,

easy to understand guidance regarding nano-materials for non-specialists. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpact• TocontributeeffectivelyinraisingtheawarenessofEuropeanconsumers,end-usersandcitizens,on

nanotechnology;• Topromotediscussionabouteffectivenanolabellingnd/ornano-productdatabasesamongEUindustries;• Toenhancesupporttogoodgovernanceinnanotechnology;• TocontributetotheimplementationoftheEuropeanCommission’sActionPlanforNanotechnology.• Topromotecollaborationandcommunicationbetweenindustries,ExpertGroups,existingscientific

networks and consumer associations.• Toconsiderinternationalcollaborations.SuggestionsonTypeofAction CSAReferencewithNfproposedactions

NT12-short and NT19-short.

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Code Title of the actionNT-S-003 EU and International Cooperation for development and promotion

ofeffective,practicableandlowcosttoxicologytestingmethodsTimeline 2015-2018Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• REACH• Regional,NationalandTransnationalSupportforInnovativeClusters• Legislationrequirestoxicologytestforwhichbigquantitiesofmateri-

als are needed, whilst SMEs usually start producing small quantity for pilot lines (quick toxicology assessment tools needed)

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

P2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Safetyassessment/end-usersconsumers• Legislationrequirestoxicologytestforwhichbigquantitiesofmateri-

als are needed, whilst SMEs usually start producing small quantity for pilot lines (quick toxicology assessment tools needed)

• ExcessofregulationcouldkillthemarketP4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Safetyofnanoproducts• Compatibilityofexistingsafetyevaluationprotocolswithnanomateri-

als (generally developed for micro, risk of false conclusions)• Safeprotocolsindifferentproductionsteps• Toxicityassessmentpredictioninshortandlongterminthewhole

lifecycleP1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

• Regional,NationalandTransnationalSupportforInnovativeClus-ters

• Clearsafetyregulationbasedonpropertytest,notinsidestructures-REACH complication

P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Legislationrequirestoxicologytestforwhichbigquantitiesofmateri-als are needed, whilst SMEs usually start producing small quantity for pilot lines (quick toxicology assessment tools needed)

• ReleasefromcompositesP1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Releasefromcomposites

P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

• Clearstandardsforsafetyandhandling• Regional,NationalandTransnationalSupportforInnovativeClus-

ters• Releasefromcomposites

P1-31:NonmainstreamMEMS • ReleasefromcompositesGAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Regional,NationalandTransnationalSupportforInnovativeClus-ters

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

• Clearstandardsforsafetyandhandling• Legislationrequirestoxicologytestforwhichbigquantitiesofmateri-

als are needed, whilst SMEs usually start producing small quantity for pilot lines (quick toxicology assessment tools needed)

SpecificChallengeNanotoxicology testing must be practicable and low-priced: this is particularly important for SMEs, that see safety assessment of their novel nanomaterials as one of the main economic barriers against entering the market.

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Implementation Roadmap on value chains and related pilot lines 153

ScopeProject should develop low-cost and practical nanotoxicology testing methods and SOPs, exploiting and further developing current research at low TRL (2-3) in order to arrive at prototype and demonstrator level (TRL 5-7). Innovative techniques such as High Throughput Screening (HTS) approaches, Toxicogenomics and High Content Analysis (HCA) may be applied. EU and International Cooperation on nanotoxicology approaches is recommended.The projects may also include more research on testing the ROS (Reactive Oxygen Species) production potential in-vitro and ex-vitro (chemical) as a simple pre-screening tool. In fact ROS-production is central to the health effects for most air pollution particles and also for many nanoparticles, but the tests have not been fully validated in the sense that they are predictive of health effects, and we are far from having libraries of ROS-potential for nanomaterial categories.Synergies should be found with current/past initiatives related to the Nanosafety Cluster. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpact• Newlowcostscreeningapproachesanddevicestoenhanceforaffordableandeffectivenanotoxicology

screening;• Facilitatefasterdefinitionofnanomaterialstoxicitymechanisms;• Enable“saferbydesign”approaches,tailoredtostakeholders’needs(modellers,industryandregula-

tors);• Datainarecognisedandaccessibledatabaseforusebeyondthelifetimeoftheproject;• Provisionofsolutionstothelong-termchallengesofnanosafetyandnanoregulation.• Coordinatedcollaboration,networkingandcommunicationofregional/national/transnationalnanotox

centers SuggestionsonTypeofAction RIA

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Code Title of the actionNT-S-004 Promotingeducation,trainingactivitiesandindustry-academia

exchangesonnanostructuredsurfacesandnanocoatingsTimeline 2015-2018Value Chain VC1, VC2, VC3Product Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• Fundingtogenerateadequateprototype• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe

tech ready and just need the proper customer. Setting up effective Industrial Networking

• Workersneedstobetrainedintheuseofnewmaterialsandproductacceptance of steel with nano oxides (there are different methods of treating components in service)

P2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Demonstratorstobevalidatedinindustrialscale• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Socialeducationandawarenessofthesocietyonthebenefitsofnewproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Environmentforinnovation:Outsourcingtheproductioncouldbringto outsourcing the ideas and creation of third parties producer.

• Productscreateneedsandexpertise• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Needforhighlevelengineers,entrepreneurs,MBA• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Needforhighlevelengineers,entrepreneurs,MBA

P1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Needforhighlevelengineers,entrepreneurs,MBA• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Needforhighlevelengineers,entrepreneurs,MBA• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

• Upscalingissues,industrialcapabilitiesoftheuniversityP1-31:NonmainstreamMEMS • Needforhighlevelengineers,entrepreneurs,MBA

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

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GAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Effectiveindustrialprocessestoscaleupnewproductsarisingfromlow TRL (lab scale - Spin off problem)

• Socialeducationandawarenessofthesocietyonthebenefitsofnewproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

• CompatibilitywithprocessstepSpecificChallengeSpecificChallengeThe process through which a degree program is added is lengthy and time-consuming, requiring commit-ment on the part of faculty, administrators and staff. The formal titles of the existing nanotechnology degree programs are mainly general (e.g., nanotechnology, nanosciences and nanotechnology, nanomolecular science,nanoengineering)andinsomecasesalittlemorespecific(e.g.,nanoelectronics,nanomaterials,nanobiotechnology, etc.). The approaches to the interdisciplinary aspects of nanotechnology vary among the different programs. In particular, education on nanostructured surfaces and nanocoatings needs an high degree of collaboration between academia and industry in order to develop suitable nanotechnology education activities which meet industry needs. Moreover industries (and particularly SMEs) need training activitiestargetedonspecificissues(e.g.technologymanagement,safetyandstandardizationaspects,metrology,technologytransferandinnovationfinancingissuesetc.).Scope• Totakeintoaccountpreviouswork(e.g.NANOEIS,PRONANOetc.)• Topromotethecollaborationofacademicinstitutionsatnational/EUleveltowardsthedevelopmentof

nanotechnology degree programs. Universities should set up schemes to encourage joint appointments, particularly between different engineering and science (biosciences, chemistry and physics) departments and exchange between industry and academia.

• Todevelopandtoperformspecificeducationandtrainingactivitiestunedfordifferentaudiences(stu-dents, SME techniciancs and employees etc.)including non-technical aspects (e.g. entrepreneurial skills, HSE and LCA aspects, standardization etc.). In particular short courses held by industry and by university personnel, designed for rapid updating and training,both of students and of skilled industry operators,concerningspecificneedsandrequirementsoftheindustries.

• Closercollaborationbetweenacademiaandindustry(humanresourcetransfer):multi-contextlearningmechanisms such as training of industry employees, postgraduate training in industry, graduate trainees and secondments to industry, adjunct faculty.

• Toincludesafetyofworkingaspects(morepracticalissues)• InitialeducationinsecondaryschoolsandevenstartingwithsmallactionsonKindergardenshouldbe

considered Target TRL NANeeded economical resources (public and private)NA

ExpectedImpact• Improvedcooperationbetweenacademia,industryandrelativeorganizationsofEUcountriesinorder

bridge the gap between educational offer and industrial needs in term of workers’ and researchers’ skills ;

• ToenhancetheemploymentopportunityofEUstudentsinnanotechnology;• Tohelppolicymakerstoidentifyprogramelementsthatareimportanttofosterthedevelopmentofpar-

ticular types of program models in the future. SuggestionsonTypeofAction CSAReferencewithNfproposedactions

NT14–short, NT15-short, NT16–short and NT3-medium.

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Code Title of the actionNT-S-005 Proofofconceptofsafetyriskassessmentandmanagementon

pilot line productsTimeline 2015-2018Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• REACH• Stablenanosysteminlifecycle:aggregatesandmatrices• Toxicityassessmentpredictioninshortandlongterminthewhole

lifecycle• Clearsafetyregulationbasedonpropertytest,notinsidestructures

-REACH complicationP2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Safetyassessment/end-usersconsumers• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

• ClearstandardsforsafetyandhandlingP4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Safetyofnanoproducts• Compatibilityofexistingsafetyevaluationprotocolswithnanomateri-

als (generally developed for micro, risk of false conclusions)• Safeprotocolsindifferentproductionsteps• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

• Proofthatnanocompositesare“safe”withfewtoxicityproblems• Clearstandardsforsafetyandhandling• Stablenanosysteminlifecycle:aggregatesandmatrices

P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

• Highqualitystandardsneeded:producingcompaniesshouldhavehigh safety standard in production and distribution (a single problem will affect public perception)

• ClearstandardsforsafetyandhandlingP1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Toxicityassessmentpredictioninshortandlongterminthewholelifecycle

• Clearsafetyregulationbasedonpropertytest,notinsidestructures-REACH complication

• ClearstandardsforsafetyandhandlingP1-31:NonmainstreamMEMS • ClearstandardsforsafetyandhandlingGAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Stablenanosysteminlifecycle:aggregatesandmatrices• Clearsafetyregulationbasedonpropertytest,notinsidestructures

-REACH complication• Proofthatnanocompositesare“safe”withfewtoxicityproblems• Toxicityassessmentpredictioninshortandlongterminthewhole

lifecycleSpecificChallengeIn nanotechnology, research is needed to enhance the current knowledge on safety aspects related to nano-enablingthermalfluids.Effectivesafetyriskassessmentsmethodsandtoolsshouldbeappliedona set of nano-related materials of actual industrial interest and actual prototypes of products. Focus on nanostructured surfaces and nanocoatings may be given.

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Implementation Roadmap on value chains and related pilot lines 157

Scope• Togatheroveralltheworldtheavailabledatasuchasexistingstandards,existingbest-practises,et

similia.• Todevelopacombinedexperimentalandcomputationalsafetyriskassessmentapproachandtotestit

on a set of actual industrial use-cases, involving key-manufacturers end-users in the energy sectors. For each use-case the following activities should be performed, including many of the following activities:

· Identifying the relevant properties for the toxicity/activity of the nanomaterials · Identifying the physicochemical and structural descriptors suitable for modeling nanomaterials · Quantitatitative structure activity analysis · In silico modeling of EHS risks of nanomaterials. For example a proper characterisation of material

release during manufacturing through development of pollutants /materials dispersion models should be performed.

· Redesigning of hazardous nanomaterial properties taking into account performance characteristics that are essential for technology/product development (safe-by-design approach). For example proper investigations about scaling the possible hazards with geometry and with time should be performed. The dependence of the risk assessment approach on such factor should be studied and assessed (memo: the relevant processes could be linear or non-linear ones).

· Carrying out the studies in line with the European “Second Regulatory Review on Nanomaterials”• TodisseminatethekeyfindingsincoordinationwithotherkeyEUandnationalsafetyandindustrial

networks (e.g. Nanosafety Cluster; ETPs like Nanofutures, ETPIS and others). Target TRL 7Needed economical resources (public and private)NA

ExpectedImpact• Developmentandpromotionofsafetyriskassessmenttoolsandmethods;• Increasedknowledgeonsafetyaspectsrelatedtonano-enabledproducts;• Datainarecognisedandaccessibledatabaseforusebeyondthelifetimeoftheproject;• Provisionofsolutionstothelong-termchallengesofnanosafetyandnanoregulations.SuggestionsonTypeofAction RIAReferencewithNfproposedactions

NT1–short, NT2-short, NT3–short, NT4–short, NT6–short and NT7-short.

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Code Title of the actionNT-S-006 Bringing nanotechnology to more traditional sectorsTimeline 2015-2018Value Chain ALLProduct Classes IdentifiedGapsNA NASpecificChallengeChange innovation is not easy, but with the right companies and partners we can embrace social issues like clean air for London and focus on nanotechnology initiatives that deliver this valueScopeThesectorsshouldbedefinedinodertoevaluatethepossibleimpactofthisaction.Take100smallcom-panies in a region and introduce their business to the advantages of nanotechnology Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactDemonstrate the practical value of nanotechnology at local business level, and where appropriate dovetail these initiatives to address sustainability and environmental issues SuggestionsonTypeofAction RIA

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Implementation Roadmap on value chains and related pilot lines 159

Code Title of the actionNT-S-007 Improvedcommunicationskillsfornano-expertsTimeline 2015-2018Value Chain ALLProduct Classes IdentifiedGapsNA NASpecificChallengeDevelop training modules aimed at students and at experts in industry. Training must involve journalists and communication experts. It should focus on communication of risks, which is especially diffcult, but essential for reaching the public in a responsible and comprehensive way. Modules should be developed fortransfertoothersitesbasedonexperiencesfromspecificworkshopsthathavebeenorginizedwithdiffernt stakeholders.ScopeTo improve the ability of nanoexperts for communication with multiplicators, in particular with media, politi-cians and teachers. The training of young experts focuses strongly on peer-to-peer communication, e.g. via papers and conference presentations. Media require completely different communication abilities, the lack of which can be a problem due to the multiplicator function. Different skills are again necessary to enable transfer to schools, which requires reaching out to teachers. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactImproving training both in universities and on the job. Improve communication with social stakeholders and the general public. Enable transfer of nano-related topics into school curricula. Enable implemenation of (risk and crisis) communication skills into university curricula. SuggestionsonTypeofAction CSA

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Code Title of the actionNT-S-008 Industry outreach to university trainingTimeline 2015-2018Value Chain ALLProduct Classes IdentifiedGapsNA NASpecificChallengeIdentify which problems exist for industry to get more involved with teaching, both on the side of industry and on the side of university. Develop recommendations to improve the linkage based on best practice examples and on interview with stakeholders, including students.ScopeRecent studies in NanoEIS show that direct involvement of industry in university training of nanoexperts isbyfarthemostefficientwaytoenablesmoothtransfertoindustryandtoensurethatteachingcontentmatches job skill needs. This is happening in very limited ways, since industy and university cooperate mostly on research. Ways for improvement should be found. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactIdentify hurdles for university - industry interaction in training on bachelor, master and PhD level. Set up procedures and activites that enhance industry involvement in training, e.g. matchmaking sites, competi-tions for best practice, rankings based on student feedback. Describe factors that enhance interaction independentofspecificsitesituationsandofespeciallyactiveindividuals.Raiseawarenessabouttheproblem, in particular within universities. SuggestionsonTypeofAction CSA

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Implementation Roadmap on value chains and related pilot lines 161

Code Title of the actionNT-S-009 Provideindustryfeedbackontheelementsofameaningfulregula-

torydefinitionofnanomaterialsTimeline 2015-2018Value Chain ALLProduct Classes IdentifiedGapsNA NASpecificChallengeBesidestheEUCommission’srecommendationforthedefinitionofnanomaterialstherearealreadyex-istingbindingdefinitionsindifferentEUregulatoryregimes(forbiocides,cosmetics),aswellasMemberStatesnationalinventories.Thescopeofthesedifferentdefinitionsneedtobeanalysedandharmonizedfor better coherence.ScopeSubstances in nanoforms are already regulated in the EU and are subject of mandatory reporting require-ments for different national inventories on nanomaterials and nano enabled products. These incoherent approaches need to be harmozied, in order to create a predictable regulatory environment in the EU. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactIncoherentdefinitionscreateanunpredictableregulatoryenvironment;harmonizingthedefinitioniscrucialtoovercomethisproblem.Howeveritiscrucialthattheelementsofthedefinitionaremeaningfulandap-plicable both for industry and enforcement authorities. These elements ideally also need to be in line with the approach of the OECD. SuggestionsonTypeofAction NA

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Code Title of the actionNT-S-010 Cooperation for developing suitable methods to avoid costly mis-

understandingsbetweelablevelandindustryuserlevelconcern-ing nano-related materials and processes

Timeline 2015-2018Value Chain ALLProduct Classes IdentifiedGapsNA NASpecificChallengeInnovative nanomaterials and related nanotechnologies often are not developed along straight action lines. In parallel, industry innovative devices designers proceed along different reasoning lines. It is almost impossible forcing such two lines to overlap.ScopeAvoiding future clashes between nanomaterials research labs and industries expecting new characteristics for innovative products. The outcome is a series of lengthy processes necessary to adjust the two sides of the problem. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactFilling the gap between type of results conceived by nano-research labs and expectations of industries interested to adopt such nanomaterials in future products or processes. Cooperation since the beginning will avoid long and costly re-arrangements. Working together will be facilitated by adopting new guidelines, typical of standardisation processes. SuggestionsonTypeofAction NA

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Code Title of the actionNT-M-001 Harmonization and standardization of protocols and development

ofaworkingagendaforeducationandtrainingonreal-lifesce-narios in several sectors

Timeline 2019-2022Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• Fundingtogenerateadequateprototype• Universitiesandresearchcentresneedprogrammesforcorrelating

their education curricula with companies’ requirements. Improve exist-ing measures in Erasmus+ and Marie Curie Actions Workers needs to be trained in the use of new materials and product acceptance of steel with nano oxides (there are different methods of treating components in service)

• Socialeducationandawarenessofthesocietyonthebenefitsofnewproductsbasedoncertifiedsafetyandeco-compatibility.Findwaysto ensure positive social perspective to new products

P2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Demonstratorstobevalidatedinindustrialscale

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

• Workersneedstobetrainedintheuseofnewmaterialsandproductacceptance of steel with nano oxides (there are different methods of treating components in service)

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Upscalingissues,industrialcapabilitiesoftheuniversity• Needforhighlevelengineers,entrepreneurs,MBA• Universitiesandresearchcentresneedprogrammesforcorrelat-

ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

• Workersneedstobetrainedintheuseofnewmaterialsandproductacceptance of steel with nano oxides (there are different methods of treating components in service)

P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Upscalingissues,industrialcapabilitiesoftheuniversity• Needforhighlevelengineers,entrepreneurs,MBA

P1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Upscalingissues,industrialcapabilitiesoftheuniversity• Needforhighlevelengineers,entrepreneurs,MBA

P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Upscalingissues,industrialcapabilitiesoftheuniversity• Needforhighlevelengineers,entrepreneurs,MBA• Universitiesandresearchcentresneedprogrammesforcorrelat-

ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

• Workersneedstobetrainedintheuseofnewmaterialsandproductacceptance of steel with nano oxides (there are different methods of treating components in service)

P1-31:NonmainstreamMEMS • Upscalingissues,industrialcapabilitiesoftheuniversity• Needforhighlevelengineers,entrepreneurs,MBA

GAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Socialeducationandawarenessofthesocietyonthebenefitsofnewproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

• Workersneedstobetrainedintheuseofnewmaterialsandproductacceptance of steel with nano oxides (there are different methods of treating components in service)

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SpecificChallengeEducation and Training on real-life scenarios, e.g. environmental factors (UV light, binding to dust parti-cles, ice crystals, associated transformation, etc). Establishment of Regulations from EU for existing and forthcoming Production Lines (i.e Occupational Health & Safety Regulations). Startingfromthescientificandentrepreneurialskillsandtrainingprovisionneedsinthefieldofadvancedmanufacturing technologies based on nanotechnologies, designing and delivering a joint improved curricula and training programmes for specialists involved in the future dynamic companies will be addressed to: (i) develop a set of competencies that should be recognized to the EU level; (ii) develop and establish study programmes with a double, multiple or joint degree; (iii) support the traditional teaching process through a collaborative platform that will provide teaching materials in digital format for students and tools for col-laboration between students, teachers and research specialists. 1. to bridge the gap between school and the job market (industry, academia) to inspire more vocations; 2. Focus on school activity that combine of hands-onexperiments,multimediaactivities,andschoolcompetitions,togetherwithreflectiveactivitiesScope• Harmonizationandstandardizationofprotocolsanddevelopmentofaworkingagendaforeducation

and training on real-life scenarios in several sectors. Education and Training on handling nanomaterials within Production Lines. Design of New Production Lines that utilize nanomaterials.

• Toincreasecollaborationbetweenindustryandeducationsystemat“teachinglevel”,Nowitismoreonscience/research. To adapt existing curricula from different educational domains (physics, chemistry, materials science, mechaics, electronics, biology, etc.) to the actual trend of nanotechnology and its social impact. To elaborate new curricula for master degrees and doctoral schools related to application of nanotechnologies. To develop new training courses for specialists from industrial SMEs and large companiesadaptedtotheirneedsforimprovingskillsinnanotechnologiesrelatedfields.

• SupportSTEMteacherstointegrateNTinteaching• Investinteachertrainingsandongoingsupportatlocal,nationalandEuropeanlevels• MovetothedirectionofamoreflexibleSTEMcurricula• CreateanEuropeanonlinehubwithe-courses&e-activitieswithsupportforlearningandonlinemod-

eration Vocational training to be considered. Some people, for ex. PhD level, to much trained for what industries/SMEs are looking for Coordination/aligment with other programmes such as “ERASMUS” will be of high value

Target TRL NANeeded economical resources (public and private)SpecificcallsinMarieCurieActionsandErasmus+witharelevantfundinglevel

ExpectedImpact• Sciencebasededucationprogramsonreal-lifescenariosofnano-enabledproductsandapplications.

Sustainable Development of Nanotechnology Sector in EU.• Raiseawarenessabouttherequiredskillsforbeingasuccessfulengineerandalsoanentrepreneurin

nanotechnology domains• ExtendthenumbersofSTEMstudentsintheuniversities.• BiggerawarnessofthestudentstotheimpactofNTontheirlifes.• TrainthefutureworkersinNTindustrySuggestionsonTypeofAction CSA

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Code Title of the actionNT-M-002 Exploitationanddisseminationofbestpracticesinthefieldof

public co-funded projects in nanotechnologyTimeline 2019-2022Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• Fundingtogenerateadequateprototype• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe

tech ready and just need the proper customer. Setting up effective Industrial Networking

• “Environmentforinnovation:Outsourcingtheproductioncouldbringtooutsourcing the ideas and creation of third parties producer. Products create needs and expertise

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)P2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Fundingtogenerateadequateprototype• Marketpenetration,useofnewproductsolution• Regional,NationalandTransnationalSupportforInnovativeClus-

tersP4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• “Environmentforinnovation:Outsourcingtheproductioncouldbringto outsourcing the ideas and creation of third parties producer. Prod-ucts create needs and expertise

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Regional/nationalguidelinesfornano-containingproductdisposal

and/or treatmentP1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Marketpenetration,useofnewproductsolution• Regional,NationalandTransnationalSupportforInnovativeClus-

tersP1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)P1-31:NonmainstreamMEMS • Marketpenetration,useofnewproductsolution

• Regional,NationalandTransnationalSupportforInnovativeClus-ters

GAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting UP ef-fective Industrial Networking

• Marketpenetration,useofnewproductsolution• Regional,NationalandTransnationalSupportforInnovativeClus-

tersSpecificChallengeTo establish a framework for exploiting and implementing integral measures based on best practices. For example, impact assessment within a project can help maximize the project impact, if the results are canalized in an appropriate way to the relevant target groups (stakeholders who may be able to make informad decisions and take action based on the information provided on the impact). This requires new methodologies, adapted to European cooperative R&D projects and with extended scope.Efficientmechanismsfortheconsultationofandinteractionwithindustryandotherstakeholderswithanadvisory role. The goal is to retrieve timely and relevant recommendations for the implementation of R&D in the project and for maximizing the market perspectives.To adress this type of issues, it is fundament to merge knowledge from science, technology and industry, management and marketing best practices, etc.

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ScopeTo create a frame for effective implementation of best practices mechanisms and actions in public co-funded projects in nanotechnology. Typical actions: collecting and disseminating best practices, implementing integral measures, providing services to Consortia and coordinators, and recommendations for funding bodies.Topics to address: exploitation and dissemination strategies, establishment of impact analysis and manage-mentmethodologies,andoperationalandscientificmanagementbestpractices.Where applicable, the process should consider also best practices in other thematic areas, like materi-als and manufacturing, so long as the lessons learned from them prove to be useful in nanotechnology projects.Creationofagoodquality“standard”thatcanbeusedandthatdefines“howtodothat”:thisis needed as the impact assessment of the project is not currently properly done and communication of developements to industry fails.Target TRL NANeeded economical resources (public and private)SpecificcallsinMarieCurieActionsandErasmus+witharelevantfundinglevel

ExpectedImpactThe framework developed as a result of these actions is expected to maximize the impact and usability of project efforts and results at all stages, guaranteeing (rather than only enabling) the general adoption of best practices in nanotechnology European scale cooperative research projects. This will involve not only the participants in the project, but also all relevant stakeholders (SMEs, R&D community, decision making bodies, funding institutions, general public). ThissetofactionsisexpectedtohelpmaximizetheEuropeanbenefitofnanotechnologyresearchprojects,preventing leakage of technology and manufacturing capabilities to other countries outside Europe. SuggestionsonTypeofAction CSA

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Code Title of the actionNT-M-003 Cross-sectorialTechnologyTransferprogrammeintheNMPfieldTimeline 2019-2022Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• Researchfunding(forbusinessdevelopment)• IntellectualPropertylegislationanditsconsequencesattheendof

the VC (e.g. Universities do not have money to protect patent and sometimes they do not protect and kill ideas)

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethetech ready and just need the proper customer. Setting up effective Industrial Networking

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)P2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Researchfunding(forbusinessdevelopment)• MultiscalebusinessforEuropeanbenefit

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• IntellectualPropertylegislationanditsconsequencesattheendofthe VC (e.g. Universities do not have money to protect patent and sometimes they do not protect and kill ideas)

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Regional,NationalandTransnationalSupportforInnovativeClus-

tersP1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• IntellectualPropertylegislationanditsconsequencesattheendofthe VC (e.g. Universities do not have money to protect patent and sometimes they do not protect and kill ideas)

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Regional,NationalandTransnationalSupportforInnovativeClus-

tersP1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• IntellectualPropertylegislationanditsconsequencesattheendofthe VC (e.g. Universities do not have money to protect patent and sometimes they do not protect and kill ideas)

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Regional,NationalandTransnationalSupportforInnovativeClus-

tersGAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting UP ef-fective Industrial Networking

• Regional,NationalandTransnationalSupportforInnovativeClus-ters

• IntellectualPropertylegislationanditsconsequencesattheendofthe VC (e.g. Universities do not have money to protect patent and sometimes they do not protect and kill ideas)

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SpecificChallengeIndicate to Industry of challenges through nanomaterials utilization.DesignoftechniqueswherenanomaterialscanbeintroducedinexistingProductionLines.Onespecificchallenge of especial interest is the design for manufacturing and integration of modeling and simulation in nano and mesoscale, and in relation to the different application sectors. On the other hand, challenges for technology transfer of advanced manufacturing to the nanotechnology industry include adaptive control technologies, auto-calibrating systems, distributed intelligence, and self-learning, adaptable production platforms. It involves, among others, adapting to partially or totally unknown process models with unidenti-fieduncertainties,performingsystemidentificationandchangingon-linethecontrolstrategiesaccordingto the real performance and process needs.ScopeWill assist the cooperation of different engineering and Industrial Sectors.Will assist in the design of new Production Lines that Utilize nanomaterials. Integration of regional research funding as well as technology transfer activities. Cross-sectorial technology transfer to integrate nanotech-nology based features and functions in different sectors, like transport, textiles, medical and consumer products. In order to extend the use of nanotechnology in the modern industry, it is needed to transfer effectively the latest innovations in advanced manufacturing technologies, such as the industrial implementation of production platforms with embedded intelligence, to the nanotechnology industry. Both topic areas involve a high degree of multidisciplinarity (ICT, biotechnology, sensors and signal processing, mechatronics and robotics, material science, etc.). Type of actions: direct technology transfer (TT) projects, but also support actions to identify the potential areas with a maximum impact for TT and coordinate TT action lines. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactSustainable Development of Nanotechnology Sector in EU. To guarantee the industrial feasibility and public acceptance of nanotechnology in all market sectors by: • Promotingmanufacturingofnanotechnologybasedinnovationswithlowinvestment,highflexibilityand

low risk of failure.• Expandingtheuseofnanotechnologyforincreasingtheadded-valueofproductsintraditionalsectors• Makingeconomicalmassandsmalllotsizeproductionofnanotechnologyenabledandenhancedprod-

ucts, down to mass customization, possible thanks to knowledge-based manufacturing platforms SuggestionsonTypeofAction CSAReferencewithNfproposedactions

NT18-short

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Code Title of the actionNT-M-004 EffectivecommunicationanddialoguewiththeEUsocietyonthe

social and economic impact of nanoTimeline 2019-2022Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• Missingcost-benefitanalysisandmarketanalysis• Socialeducationandawarenessofthesocietyonthebenefitsofnew

productsbasedoncertifiedsafetyandeco-compatibility.Findwaysto ensure positive social perspective to new products

P2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Missingcost-benefitanalysisandmarketanalysis

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Safetyofnanoproducts• Socialeducationandawarenessofthesocietyonthebenefitsof

newproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Socialeducationandawarenessofthesocietyonthebenefitsofnewproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Socialeducationandawarenessofthesocietyonthebenefitsofnewproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

GAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Socialeducationandawarenessofthesocietyonthebenefitsofnewproductsbasedoncertifiedsafetyandeco-compatibility.Findways to ensure positive social perspective to new products

SpecificChallengeAvoid fatalistic scenarios (Grey goo, self-replicating nanobots, military or terrorist use, etc.) that mixing sciencefictionandscientificdatawarningofapossibleendoftheworldand/orthelostofhumanvalues.Moredifficultyforethicaldebateduetomultidisciplinarity?Although,incontrast,couldbeabenefit(usualdialogue between disciplines involved in nanotechnology). Support and legitimize: the recognition of this fieldasapositiveactivityforsociety.Promotesocialdebateandcitizenparticipation.Professional,twoways communication, retrieving also feedback information of relevance to generate recommendations and guidelines for increasing the acceptance of products manufactured with nanotechnology and for adapting future nanotechnology R&D to the needs and expectations of the society.ScopeSameasNT-S-002toreflectontheconvenienceofaddressingsomeissuesraisedintheethicaldebateon nanotechnology development. Include also environmental impact and, if relevant, other dimensions of impact, based on integrated impact analysis models.Specifictargetedactions/measuresfordifferenttargetgroupswithinthesociety.Basedonprevioussocialengagement activities (e.g. NanoDiode, NanOpinion, NanoEIS, etc.) Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactEquitable distribution of knowledge: Protection excessive and/or improper of knowledge. Patents. Social distribution of nanotechnology advances (between individuals and countries). Prevent adverse currents of opinion. Provide governance models that allow safety and production activities without hindering research, innovation and progress in this area.Larger acceptance and adoption of products and services based on / or using nanotechnology. Increased awareness on the implications. SuggestionsonTypeofAction CSAReferencewithNfproposedactions

NT5-medium

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Code Title of the actionNT-M-005 Implementation of standardization methods for characterizing

and/orperformancevalidationofnanoparticlesTimeline 2019-2022Value Chain VC2 and VC3Product Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• ISOstandardization• Clearstandardsforsafetyandhandling• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

• LackofmetrologyintheindustrialframeandatthemicronscaleP2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• ISOstandardization

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Clearstandardsforsafetyandhandling• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

• Releasefromcomposites• Lackofmetrologyintheindustrialframeandatthemicronscale

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Clearstandardsforsafetyandhandling• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

• Releasefromcomposites• Lackofmetrologyintheindustrialframeandatthemicronscale

P1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Lackofstandards,lackofinfrastructure,organisationbody

P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Lackofstandards,lackofinfrastructure,organisationbody• Clearstandardsforsafetyandhandling• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

• ReleasefromcompositesP1-31:NonmainstreamMEMS • Lackofstandards,lackofinfrastructure,organisationbodyGAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Lackofmetrologyintheindustrialframeandatthemicronscale• Clearstandardsforsafetyandhandling• Releasefromcomposites• Highqualitystandardsneeded:producingcompaniesshouldhave

high safety standard in production and distribution (a single problem will affect public perception)

SpecificChallengeNAScopeStandards are known, but there is a lack on how to implement them. Of what this means. NanoMedicine Platform already has some projects dealing with this. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactNASuggestionsonTypeofAction RIA

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Code Title of the actionNT-M-006 EstablishmentofaPlatformwhereallBestAvailableTechnologies

(BAT)inthecorresponidPILOTSareassessed.Timeline <2020Value Chain ALLProduct Classes IdentifiedGapsNA NASpecificChallengeIndicate to Industry of challenges through nanomaterials utilization.ScopeWill assist the cooperation of different engineering and Industrial Sectors. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactSustainable Development of Nanotechnology Sector in EU. SuggestionsonTypeofAction NA

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Code Title of the actionNT-M-007 Responsible research and Innovation (RRI) as a cross-cutting is-

sue in H2020Timeline medium Value Chain ALLProduct Classes IdentifiedGapsNA NASpecificChallengeThe challenge is that considerations of the foreseen end product and its potential impacts on human and environmetnal health should not be an afterthought, but a driving force for innovation across value chainsScopeResponsible Research and Innovation means that societal actors work together during the whole research and innovation process in order to better align both the process and its outcomes, with the values, needs andexpectationsofEuropeansociety.Thescopehastwoelements:1)reflexivityofresearchersand2)addressing societal challenges. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactThe expected impact is, on the short term, pilot projects that involve stakeholders to integrate societal needs and values in decision making processes, and on the longer term, an innovation process that is better attuned to societal needs and values. It is imperative that these notions do not just appear in the SwafS programme but are integrated in each of the technological programmes such as NMBP. SuggestionsonTypeofAction CSA

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Implementation Roadmap on value chains and related pilot lines 173

Code Title of the actionNT-L-001 Newbusinessstrategiesandbusinessmodelsfornano-enabled

productsTimeline >2022;Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• Missingcost-benefitanalysisandmarketanalysis

P2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• MultiscalebusinessforEuropeanbenefit• Missingcost-benefitanalysisandmarketanalysis

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Regional,NationalandTransnationalSupportforInnovativeClus-

tersP1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Nopilotlineavailable/Moneyforpilotlines• Insomecasesnanoproductsarenotdevelopedtobescalablein

production and again new innovation is necessary• Environmentforinnovation:Outsourcingtheproductioncouldbring

to outsourcing the ideas and creation of third parties producer. Prod-ucts create needs and expertise

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)P1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Nopilotlineavailable/Moneyforpilotlines• Insomecasesnanoproductsarenotdevelopedtobescalablein

production and again new innovation is necessary• Environmentforinnovation:Outsourcingtheproductioncouldbring

to outsourcing the ideas and creation of third parties producer. Prod-ucts create needs and expertise

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Nopilotlineavailable/Moneyforpilotlines• Insomecasesnanoproductsarenotdevelopedtobescalablein

production and again new innovation is necessary• Environmentforinnovation:Outsourcingtheproductioncouldbring

to outsourcing the ideas and creation of third parties producer. Prod-ucts create needs and expertise

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)P1-31:NonmainstreamMEMS • Nopilotlineavailable/Moneyforpilotlines

• Insomecasesnanoproductsarenotdevelopedtobescalableinproduction and again new innovation is necessary

• Environmentforinnovation:Outsourcingtheproductioncouldbringto outsourcing the ideas and creation of third parties producer. Prod-ucts create needs and expertise

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)GAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• Competitionduetocommoditization,relatedtotheissueofcost• Marketpenetration,useofnewproductsolution• Regional,NationalandTransnationalSupportforInnovativeClus-

ters

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SpecificChallengeThe Integration of the other Actions (esp. NT-M004) will assist to: 1) the access of Nanotechnology com-panies to Public and Private funding opportunities, 2) the development of Business Plans in new busi-nessenvironments,3)therealizationoftheseBusinessPlans.Alllineoffundingshouldreservefinancialresourses for companies to traverse the valey of death and mostly importantly the missing gap that is the process of scaling-up the research to viable mass productition. It is of capital importance to generalize collaboration and resource sharing schemes in which all actors and infrastructure owners are involved. This can include new logistics, cost, management and business modelsScopeSpecificsupportactions,dealingwithaspectsrelatedtotheestablishmentofcomplexintegratedmanu-facturing networks operating in a dynamic way, and/or supporting the integration of SMEs in them. Entre-prenurial concepts and actions “small projects” for students to become entrepreneurs Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactSustainable Development of Nanotechnology Sector in EU.To promote the establishment of complex integrated manufacturing networks operating in a dynamic way, and to support the integration of SMEs in them.Suchvalue-addedcooperativeswillensureaflexiblestructureofindustryandR&D,abletoadaptand innovate more rapidly. Further, the increase involvement of SMEs in the network of process/supply chains, logistics and materials would favour a closer link to the consumer and a more open spreading of the know-how on leading-edge technologies, in comparison to classical structures driven by large scale leading industries.ThisisexpectedtoreinforceEurope’spositionasleadingproducerofinthefieldofNanotechnology,bothin manufacturing of products and in R&D. SuggestionsonTypeofAction CSAReferencewithNfproposedactions

NT7-medium

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Code Title of the actionNT-L-002 EducationonMarketingandCommunicationSkillsinNMPfieldTimeline >2022;Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• Missingcost-benefitanalysisandmarketanalysis• Abilitytoidentifymarketopportunities,oftenacompanymayhavethe

tech ready and just need the proper customer. Setting up effective Industrial Networking

• IntellectualPropertylegislationanditsconsequencesattheendofthe VC (e.g. Universities do not have money to protect patent and sometimes they do not protect and kill ideas)

• Competitionduetocommoditization,relatedtotheissueofcostP2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• MultiscalebusinessforEuropeanbenefit• Missingcost-benefitanalysisandmarketanalysis

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

P1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Needforhighlevelengineers,entrepreneurs,MBA

P1-11: Lab on chip (including bio-compatibleor toxicscaf-folds,activeinfluenceofcellgrowth&differentiation)

• Needforhighlevelengineers,entrepreneurs,MBA

P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Needforhighlevelengineers,entrepreneurs,MBA• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting up effec-tive Industrial Networking

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Universitiesandresearchcentresneedprogrammesforcorrelat-

ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

P1-31:NonmainstreamMEMS • Needforhighlevelengineers,entrepreneurs,MBAGAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• DifficultiesinKnowledgeTransfer(newmoreeffectivewayneeded)• Abilitytoidentifymarketopportunities,oftenacompanymayhave

the tech ready and just need the proper customer. Setting UP ef-fective Industrial Networking

• Universitiesandresearchcentresneedprogrammesforcorrelat-ing their education curricula with companies’ requirements. Improve existing measures in Erasmus+ and Marie Curie Actions

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SpecificChallengeCreating the awareness for the potentials of nanotechnology and nanoscience from kindergarten to tertiary institutions including universities. Tools and structures on nanoscience for education. Building the-state-of-the-artslabsgeographicallydistributedinzonesforthepublicuse.Specifically,educationandprovisionofinfrastructures should include: Training of undergraduates, graduates and doctorate studies at universities and research labs through the broad research program.Via training agencies, award fellowship to students toparticipateinnanotechnologyprogramtoallowflexibilityinchoosingtrainingprogramsespeciallythosethat cross disciplines. The challenge is to create both adapted knowledge and professional workforce for marketingandcommunicationintheNMPfield.ScopeNano-education: Teaching nanotechnology to primary and secundary school. : A well-educated citizenry, a skilled workforce, and supporting infrastructures of instrument, equipment, and facilities are very essential intheinitiative.Besidescreatingaframefortrainingopportunitiesandeducationalmaterial,specificac-tions could also deal with the restructuration of classical models in marketing and communication theory, and ist ad-hoc adaption to the new products and technologies based on nano. Target TRL NANeeded economical resources (public and private)NA

ExpectedImpactIntroducing nanoscience into pre-service teacher education programmes and reports about the design of anin-serviceteachertrainingprogrammefocusingspecificallyontheuseofmodelstoteachandlearnimportant nano techniques, such as atomic force microscopy. Bring nanoscience concept into education for students of all ages. To provide the means for maximizing the commercial and social impact of nano-technology SuggestionsonTypeofAction CSAReferencewithNfproposedactions

NT4-medium

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Code Title of the actionNT-L-003 JointEU&MSactivitytosupportEUnano-regulationTimeline >2022;Value Chain VC2 and VC3Product Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• ISOstandardization• REACH• Legislationrequirestoxicologytestforwhichbigquantitiesofmateri-

als are needed, whilst SMEs usually start producing small quantity for pilot lines (quick toxicology assessment tools needed)

• ExcessofregulationcouldkillthemarketP2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Safetyassessment/end-usersconsumers• ISOstandardization• Clearsafetyregulationbasedonpropertytest,notinsidestructures

-REACH complicationP4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• Buildingofknowledge• Safetyofnanoproducts• Uncertaintyofregulationfornano• Clearsafetyregulationbasedonpropertytest,notinsidestructures

-REACH complicationP1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Clearsafetyregulationbasedonpropertytest,notinsidestructures-REACH complication

• Excessofregulationcouldkillthemarket• Substitutionofrareearthmaterials(poorlyavailableforpolitical,

geographical reasons)• Releasefromcomposites

P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Clearsafetyregulationbasedonpropertytest,notinsidestructures-REACH complication

• Excessofregulationcouldkillthemarket• Substitutionofrareearthmaterials(poorlyavailableforpolitical,

geographical reasons)• Releasefromcomposites

GAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Clearsafetyregulationbasedonpropertytest,notinsidestructures-REACH complication

• Substitutionofrareearthmaterials(poorlyavailableforpolitical,geographical reasons)

• Legislationrequirestoxicologytestforwhichbigquantitiesofmateri-als are needed, whilst SMEs usually start producing small quantity for pilot lines (quick toxicology assessment tools needed)

• ReleasefromcompositesSpecificChallengeNAScope• Tosupporttheevaluationofexistingdataonregulatorytestingofnanomaterials• Toevaluateexisitingmeasurementsonindividualrisksbothforexposureandtoxicity• Tosupportsafe-by-design• Activepolicyandstakeholderdialoguetodiscusschallengesfacingnano-regulationsTarget TRL NANeeded economical resources (public and private)NA

ExpectedImpact• Overviewofexistingregulatoryresearchdara• Evaluationandassessmentoftoxicityandexposuredata• Provisionofsolutionstothelong-termchallengesofnanosafetyandnanoregulations.• Educationandtrainingonregulatorytestingandriskassessment,riskcontrol,preventionandmitigationSuggestionsonTypeofAction CSAReferencewithNfproposedactions (if any)

NT1-medium and NT2-medium

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Code Title of the actionNT-L-004 EU and International Cooperation for the development of added-

value,lowcostandeco-friendlynano-relatedproductsadopting“safety by design” approach

Timeline >2022;Value Chain ALLProduct Classes IdentifiedGapsP2-4: Nanostructured antimicro-bial,antiviralsurfaces(medicaldevices,hospitals,etc.)

• REACH• ISOstandardization• Toxicityassessmentpredictioninshortandlongterminthewhole

lifecycle• Pre-productionsuitabletohigh-volumemanufacturing(HVM),sup-

port of initial phase is neededP2-9: Nanocoatings for me-chanically enhanced surfaces (e.g.,abrasionresistance,lowfriction)

• Needforlowcostefficientprocesses/product• Needforlowcostmaterialswithhighaddedvalue• Safetyassessment/end-usersconsumers• ISOstandardization

P4-4:Materialswithcustom-izedthermal/electricalconduc-tivityproperties(e.g.skinsofaircraftsforlightingprotection,thermallayer,etc.)

• SafetyofNANOproducts• Safeprotocolsindifferentproductionsteps• Competitionduetocommoditization,relatedtotheissueofcost• Releasefromcomposites

P1-27: 3D printed Polymeric mi-crofluidicMEMSlikenozzlesorfilters;

• Proofthatnanocompositesare“safe”withfewtoxicityproblems• Pre-productionsuitabletohigh-volumemanufacturing(HVM),sup-

port of initial phase is neededP1-28: 3D printed Polymeric mechanicalMEMSforsensorapplications

• Releasefromcomposites• Stablenanosysteminlifecycle:aggregatesandmatrices

P1-5: Microelectromechanical systems - MEMS (includingMicro or Nano Opto-Electro-MechanicalSystems)

• Proofthatnanocompositesare“safe”withfewtoxicityproblems• Pre-productionsuitabletohigh-volumemanufacturing(HVM),sup-

port of initial phase is needed

P1-31:NonmainstreamMEMS • Releasefromcomposites• Stablenanosysteminlifecycle:aggregatesandmatrices

GAPSOUTLINEDinVC3corre-latedwithalltheselectedpilotlines

• Competitionduetocommoditization,relatedtotheissueofcost• Stablenanosysteminlifecycle:aggregatesandmatrices• Pre-productionsuitabletohigh-volumemanufacturing(HVM),sup-

port of initial phase is needed• Proofthatnanocompositesare“safe”withfewtoxicityproblems

SpecificChallenge• Targettogetauniformapproachtosustainablesolutionsimplementation• Aggregatebestpractisesandqualificationmethodologiestoattaincompetitiveandsustainablesolutions

complying with safety in the framework of sustainable development of nano-based productsScope• Toapply“safetybydesign”approachinproductandprocessdevelopment• Toapply“eco-design”approachinordertodevelopcosteffectiveandenvironmentalfriendlyproduct

and related manufacturing processes• Toaggregateselectandimplementbestavailableprocessingtechnologiescomplyingwith:a)addressed

product functionalities; b) cost effectiveness; c) environmental sustainability• Todevisequalityperformanceindicators,includingthefunctional,economicandenvironmentaldimen-

sions in order to rank BATs• Tohaveasetofstandardizedriskassessmenttoolsfornanomaterialevaluationonrisk• Toevaluatetheexistingnanomaterialsonmarketvalueaccordingtosustainableandresponsiblere-

search and innovation• Toprovidestandardizedevaluationandcertificationforcostandeco-friendlynanomaterialproduction

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Target TRL NANeeded economical resources (public and private)NA

ExpectedImpact• Attainmentofanintegratedandefficientapproachtosustainabledevelopment• Valueaggregationderivedbyknowhowin:a)productsdevelopment,b)sustainabilityassessmentmeth-

odology, c) safety assessment best practises• Maximisationofefficiencyandeffectivenessbyavoidingreplicationofeffortstowardssustainabilityand

competitiveness• Providecostandeco-friendlymanagementofnanomaterialtestingandproduction• Provideriskassessmentandefficentymodellforpreentionandprotectionmeasures(human&environ-

ment)• Establishmentoftwo-waydialoguetoolsfordataexchange,transperencymeasuresandtrainingSuggestionsonTypeofAction CSAReferencewithNfproposedactions

NT2-short and NT1-long

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11 Appendix VI

AppendixVI-PilotLine1Nanostructured surfaces and nanocoatings Description

Code Title of the actionPilot 1a (VC2) NanostructuredAntimicrobialSurfacesSpecificChallengeInfections by pathogenic microorganisms adhering on various surfaces kill worldwide more people than any othersinglecause.Thesediseasesareofparticularsignificanceinhospitals(i.e.,surgeryequipment,medi-cal devices, textiles, surfaces/furniture, etc.) where great efforts and important overheads are consumed forthestruggleagainstinfections.Therealizationthattheeraofantibioticstocontrolinfectiousbiofilmsismoving towards the end (i.e., increasing prevalence of antibiotic resistant bacterial strains) together with a growing demand for superior quality medical devices and need to improve sanitation in hospital premises are driving forces for the development of nanostructured antimicrobial surfaces.ScopeProposals should address the development and demonstration in relevant industrial environments of reliable manufacturing processes to obtain nanostructured surfaces with antimicrobial, biocompatible, anti-adhesive properties for applications in medical devices, implants, hospital environment sterility (e.g., walls, furniture, door knobs, nonwoven fabrics, surgery equipment, etc.), health care products, etc. The fabrication of new antimicrobial surfaces, or the improvement of existing ones via the application of surface coatings, or the modificationofthesurfacearchitecture,inordertoeliminateorsubstantiallyreducetheextentofbacterialattachment on these surfaces are foreseen. A multi-functional approach should be followed for the de-velopment/modificationofthenanostructuredsurfaces.Thisapproachshouldcombinetheanti-adhesiveprinciple (i.e., prevention of bacteria to adhere to the surface) with bactericidal strategies (i.e., killing of microorganisms either before or after they have contacted the surface). The developed nanostructured surfacesshouldinhibitbiofilmformation,exhibithighefficacytowardsabroad-spectrumofbacteriaandbetailoredaccordingtothespecificapplication.Proposalsshoulddemonstratetheeffectivenessofthedeveloped technologies through the pilot-scale manufacturing of nanostructured antimicrobial surfaces.For this topic, proposals should include an outline of the initial exploitation and business plans, which will be further developed in the proposed project.StartingTRL 4-5Target TRL 7ExpectedImpact• Improvedhygieneinhospitalenvironmentsandpreventionofcross-infections.• Reducedcostsrelatedtothetreatmentofinfectiousdiseasesacquiredduringhospitalization.• Improvedqualityoflifeforpatientsinneedofmedicaldevicesorimplants.• Novelmaterialsdesignresultingincreationofnewknowledge.• Integrationofstate-of-the-artnanotechnologyinthetraditionalproductionofcoatings/surfaceswillgive

a market advantage to the European coatings sector via the development of functional antimicrobial nanocoatings.

• IncreasethecompetitivenessofEuropeanindustriesandexpandtheirmarkettopotentialnon-EUcountries.

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Code Title of the actionPilot 1b (VC2) NanocoatingsforMechanicallyEnhancedSurfacesSpecificChallengeEach year malfunction or damage due to abrasion costs millions of dollars of infrastructure maintenance worldwide. For example, when the moving parts of a machine are subject to friction, more energy is required fortheirmovement,themachinedoesnotoperateasefficiently,andthepartshaveatendencytowearover time. But if parts could be manufactured with tough, ‘slippery’ surfaces, friction would be eliminated or significantlyreduced,lessenergyinputwouldberequiredandthepartswouldlastlonger.Nanostructuredcoatings provide improved scratch and abrasion resistance, super hardness that rivals diamond in perfor-mance, improved wear resistance and corrosion inhibition. In addition, they meet stringent regulatory and safety requirements. Furthermore, as environmental restrictions on the use of lubricants grow tighter, and costsassociatedwithdisposalincrease,thereisagrowingdemandforlowfrictionthinfilmcoatingsthatallow contacting surfaces to rub against one another with reduced friction and wear. ScopeProposals should address the development and demonstration in relevant industrial environments of reli-able manufacturing processes to obtain a new class of nanostructured coatings with superior mechani-calproperties,suchashardnessandlowfrictioninordertoincreaseoperatingefficiencyandoperatinglifetime of wear-intensive industrial components (e.g., machine parts, tools for metal cutting, etc.) used in automotive, aerospace, maritime, process industry, etc. Low friction could be the result of the presence of solid lubricants in the structure of the nanocoatings. Emphasis could be placed on examining appropriate processing techniques to eliminate porosity and achieve nanocoatings exhibiting a maximum combination of hardness and toughness. Proposals should demonstrate the effectiveness of the developed technologies through the pilot-scale manufacturing of high-wear-resistant nanocoatings. Optimization of composition and processing on the laboratory scale will serve as an initial milestone, providing industrial partners with a “template” for developing their industrial-scale procedures. For this topic, proposals should include an outline of the initial exploitation and business plans, which will be further developed in the proposed project.

StartingTRL 4-5Target TRL 7ExpectedImpact• Increaseofperformanceanddurabilityofwear-intensiveindustrialcomponents.• Reductionofinfrastructuremaintenancecosts.• Reductionofoperationalcostsduetoenergysavings.• Environmentalimpactwitheco-friendlynanocoatings.• Integrationofstate-of-the-artnanotechnologyinthetraditionalproductionofcoatingswillgiveamarket

advantage to the European coatings sector via the development of nanocoatings for mechanically en-hanced surfaces.

• IncreasethecompetitivenessofEuropeanindustriesandexpandtheirmarkettopotentialnon-EUcountries.

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12 Appendix VII

AppendixVII-PilotLine2Manufacturing of lightweight multifunctional materials with nano-enabled customised

thermal/electrical conductivity properties Description

Code Title of the actionPilot 2 (VC4) Manufacturingoflightweightmultifunctionalmaterialswithnano-

enabledcustomisedthermal/electricalconductivitypropertiesSpecificChallengeAdvanced multi-functional materials with customized thermal/electrical conductivity properties enabled by nanotechnologies provide new opportunities within electrical & electronics applications, in particular in areas like electrical and electronics, energy and power automotive and aerospace (e.g. capacitors, skins of aircraftsforlightingprotection,thermallayers,insulationpanelsforenergyefficientbuildings,etc.).Despiteprevious efforts, the productivity of forming methods for nanoenabled multifunctional materials is still strug-gling to meet the increasing demand. This hinders the further integration of nanoenabled multifunctional materials into practical large-scale applications and limits current uses to niche-markets.The need for such materials, affordable and industrially robust, calls for safely, consistently and cost-effectively upscaling of these widely researched materials and their manufacturing processes. This shall be achieved by a combination of interdisciplinary knowledge from the academia and industry to facilitate technological convergence and offers insight for upscaling materials production.The aim is to reduce the cost of these materials and their production, and establish process control and characterization approaches for an industrial production. Societal challenges calls for industries to reduce the carbon footprint. The action should in particular dem-onstrate how the upscaling and use of these new materials can help, by consuming less energy during their manufacturing process, their use and recycling, and overall reducing total LCC and environmental impact.New entrants into the market are expected, including new SME materials manufacturers, facilitated by the feasibility to be reached for the new materials and their manufacturing.ScopePilot line development may include:• Newmethodsand/orinstrumentationwithrealtimecharacterizationformeasurement,analysisand

operations at the nanoscale to characterize relevant materials process properties; • Increasingthelevelofrobustnessandrepeatabilityofsuchindustrialprocesses;• Optimizingandevaluatingtheincreasedperformancesoftheproductionlinesintermsofproductivity

and cost-effectiveness; • AssessingthefunctionalityandperformanceoftheproducednewmaterialovertheentireLifeCycleof

thefinalendproducts.StartingTRL 4-5Target TRL 7

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ExpectedImpactThe improved properties of advanced functional material with customized thermal/electrical conductivity propertiescanbenefitenduserindustriessuchasautomotive,aerospace,consumerdurables,construc-tion, electronics, healthcare, and energy.Directbenefittotheinvolvedindustriesintheformofreducedcostsandfullconsiderationofenvironmentaland safety legislation. In-line process control technologies should reach industrial maturity and robustness.Characterization methods also need to be established in support of recognized quality standards.Compatibility with existing production lines should facilitate the fast and easy integration of the new produc-tion technology with materials producers Through complementarity with on-going innovations and high R&D investments in automotive, automa-tion, energy, construction, electronic lighting, aerospace and medical industries, the action should help driving the demand for advanced and smart materials in Europe as well as support the penetration of new markets worldwide. It may be expected that new trade associations/platforms/professional networks will result from the activity and support this target, and increase chances of entrance for breakthrough concepts in niche markets.SME EU materials manufacturers, facilitated by the feasibility to be reached for the new materials and their manufacturing, will enter the market or improve their market positioning.

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13 Appendix VIII

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13 Appendix VIII

AppendixVIII-PilotLine3Printed microfluidic MEMS and biological applications Description

Code Title of the actionPilot 3a (VC1) PrintedmicrofluidicMEMSandbiologicalapplications:nozzles,

filters,sensorapplicationsandmulti-usechipSpecificChallengeMicrofluidicsisanemergingtechnologyinthebroadermarketofMEMS,whichenablesprecise,automatedmanipulationoftinyvolumesoffluid(oftennanolitersorevenpicoliters).Itisprimarilyusedinbiologicaland pharmaceutical applications, but is also applied for e.g. chemical and energy applications, (3D) print-ing,filters,etc.Duringthelastdecades,microfluidicsystemshaveevolvedfromrelativelysimplesingle-functiondevicesto multiple-function analytical systems used for a wide range of (biological) applications. This increase in scope, complexity, and integration has presented new challenges. Examples:• Stricterdemandsonmanufacturingcapabilities(nanometertomicrometerscale,materials)• Moredemandingcharacterization,inspectionandmetrologyrequirements• Improvedassembly,packaging,andhandlingtechniquesneeded• Enhancingscalabilityofproductionand• MorecomplexmanufacturingchainsposeintegrationchallengesScopeProposals should address the development and demonstration of reliable manufacturing processes to obtainprintedpolymericmicrofluidicMEMSdevicesfornozzlesorfilters,sensorapplications,ormulti-usechips.ThechosenapplicationforwhichamicrofluidicMEMSdeviceismanufacturedneednotbelimitedtohealth-care and biology: also other devices are allowed. E.g. devices that have a non-medical positive effect onhealth(e.g.hygieneandcleaningsolutions),chemicalandenergyapplications,(3D)printing,filters,etc.A wide range of printing technologies can be chosen to obtain the proposed product(s); printing includes also injection molded nanostructures in plastic, imprinting, additive manufacturing, etc. For this topic, proposals should include an outline of the initial exploitation and business plans, which will be further developed in the proposed project.StartingTRL 4-6Target TRL 7

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ExpectedImpactImpacts:• Improvedhealth/qualityoflife:bothdevelopedanddevelopingmarkets• Sustainableproduction&energysaving• Increasedcross-regioninteractionsbetweenEUcompanies• BringtheavailableseedstogetherinapilotlinewiththepotentialtogiveEuropeacompetitiveedgeon

Printed Polymeric MEMS.• Low-cost&resourceefficientproductionofhealth-promotingdevices• Highlyscalableproductiontechnology• AmountofnewbusinessperEUcalltopic:20Xcallbudget• HigherindustrialleadershipinNext-Generationmicrofluidichealth-promotingdevices,”don’tmissthe

boat”• PlatformforSMEstodevelopmicrofluidicMEMSbasedproducts,increasedturnoverforSME• RenewedproductionlinesinEurope,version2.0ofinstalledbase,putEuropeintherightpositionto

produce innovative MEMS devices. Cover the initial costs.

Quantative targets:• 800M€ofnewbusinessgenerated(140M€perproject)• 5(1foreachproject)companiesgrownfromstart-uptoSMElevel• Bringtogether25companies(5foreachproject)thathavetherequiredtechnologiesatTRL5-7.• 15SMEs(2-5foreachproject)willhavedoubledigitgrowth• 15SMEs(2-5foreachproject)willstrengthentheirpositionbycollaboratingwithotherSMEs

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Code Title of the actionPilot 3b (VC1) PrintedmicrofluidicMEMSandbiologicalapplications:Bio-med-

ical/bio-physicalssensors,actuatorsandotherdevicesSpecificChallengeIn the last decade, application of micro- and nano-technology for biological and medical applications has foralargepartbeenintheformofmicrofluidicMEMS.Thesehaveevolvedfromrelativelysimplesingle-function devices to multiple-function analytical systems used for a wide range of (biological) applications. However, numerous possible applications are now also emerging for other forms of MEMS and Nano-technology, and many new applications are expected in the future as breakthroughs in research will allow synergiesbetweendifferentandcurrentlyunrelatedfieldsoftechnologies(e.g.biologyandmicroelectron-ics). While these synergies can lead to exciting new biological products they also result in a large increase in scope, complexity, and integration. This has presented new challenges. Examples:• Exploitingadvancesinunrelatedfieldsforuseinbiologicalapplications• Stricterdemandsonmanufacturingcapabilities(nanometertomicrometerscale,used(combinationof)

materials) • Moredemandingcharacterization,inspectionandmetrologyrequirements• Improvedassembly,packaging,andhandlingtechniquesneeded• Enhancingscalabilityofproductionand• MorecomplexmanufacturingchainsposeintegrationchallengesScopeProposals should address the development and demonstration of reliable manufacturing processes with metrology or sensors to control and stabilize processes for obtaining Bio-medical/bio-physicals sensors, ac-tuators or other devices for biological applications. The chosen applications should be linked to health-care, biology and/or pharmacy. Examples are Lab-on-chip, bio-medical/bio-physical sensors, organ-on-a-chip, bio-compatibleortoxicscaffolds,activeinfluenceofcellgrowth&differentiation,etc.Applicationsarenotstrictlylimitedtomicrofluidicdevices,otherprintedbiologicaldevices(sensors/actuator)areallowedaswell.A wide range of printing technologies can be chosen to obtain the proposed product(s); printing includes also injection molded nanostructures in plastic, imprinting, additive manufacturing, etc. For this topic, proposals should include an outline of the initial exploitation and business plans, which will be further developed in the proposed project.StartingTRL 4-6Target TRL 7ExpectedImpactImpacts:• Improvedhealth/qualityoflife:bothdevelopedanddevelopingmarkets• Sustainableproduction&energysaving• Increasedcross-regioninteractionsbetweenEUcompanies• BringtheavailableseedstogetherinapilotlinewiththepotentialtogiveEuropeacompetitiveedgeon

Printed Polymeric MEMS.• Low-cost&resourceefficientproductionofhealth-carerelateddevices• Highlyscalableproductiontechnology• AmountofnewbusinessperEUcalltopic:20Xcallbudget• Higherindustrialleadershipinprintedbiologicalapplications• PlatformforSMEstodevelopavarietyofNext-Generationbio-medical/bio-physicalproducts

Quantative targets:• 800M€ofnewbusinessgenerated(140M€perproject)• 5(1foreachproject)companiesgrownfromstart-uptoSMElevel• Bringtogether25companies(5foreachproject)thathavetherequiredtechnologiesatTRL5-7.• 15SMEs(2-5foreachproject)willhavedoubledigitgrowth• 15SMEs(2-5foreachproject)willstrengthentheirpositionbycollaboratingwithotherSMEs

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Code Title of the actionPilot 4a (VC1) NonmainstreamMicro-Electro-MechanicalSystemsandArchitec-

turesA:AdvancedCMOScompatibledigitalfabricationSpecificChallengeAlthough the development of MEMS technologies enabled a huge range of possibilities, the range of com-mercial MEMS products is still relatively small (mainly accelerometers, digital micro-mirror devices, pressure sensors, and inkjet nozzles), even though the associated volumes are already quite large. It is expected to exhibit strong growth the coming years.Next generation MEMS will have to do more complicated things than the ones already on the market and in that sense be non-traditional. In this pilot the main challenge is to advance the state of the art of MEMS fabrication with CMOS compatible digital fabrication techniques for MEMS (e.g. direct use of printed ce-ramics, printed ceramics as hard masks, other digital fabrication techniques). This increase in complexity presents new demands on manufacturing tool capabilities, material science/formulation, and MEMS design concepts. Because of the more complicated nature, todays characterization and metrology tools need to be renewed, they face new challenges that current systems are not able to meet.ScopeProposals should address the development and demonstration in relevant industrial environments of reliable manufacturing processes and metrology/control systems to produce novel MEMS devices using advanced CMOS compatible digital fabrication technique(s) as one or more of the processing steps.“CMOScompatibility”willbeachievedbycreatingorfinishingMEMSstructuresontopofa(almost)finishedwafer, or by using processes that are allowed in regular CMOS manufacturing facilities (i.e. processes that do not present contamination risks for CMOS manufacturing). For this topic, proposals should include an outline of the initial exploitation and business plans, which will be further developed in the proposed project.Activities within the pilot line will address a.o.:• Process(equipment)development:improveprintingtechnology(resolution,throughput,reliability),mate-

rial formulation• Metrologyandsensorsystemstostabilizeandimprovedevelopedprocesses,toassessperformance,

reliability, and robustness.• ProduceaMEMSdemonstratorthatmixesCMOSprocesseswithdigitalfabrication.Preferably,digital

fabrication is a key enabler.StartingTRL 4-6Target TRL 7ExpectedImpactImpacts:• Growthofqualityjobs• Moresustainableproduction(material,energy)• Increasecross-regioninteractionbetweenEUcompanies• BringtheavailableseedstogetherinapilotlinewiththepotentialtogiveEuropeacompetitiveedgeon

CMOS compatible digital fabrication techniques for MEMS• IncreaseTRLofrelevantKETsto7(e.g.High-resolutionadditivemanufacturing)• NewEnablingTechnology→novelhigh-performanceproductspossiblewithassociatedeconomicgrowth• Digitalfabricationcanlowerrequiredinvestmentfornewproducts• AmountofnewbusinessperEUcalltopic:20Xcallbudget• IncreaseofindustrialleadershipinadvancedintegrationofMEMSandelectronics• AdvancedintegratedMEMSsolutionsmoreattainableforSMEs

Quantative targets:• 800M€ofnewbusinessgenerated(140M€perproject)• 5(1foreachproject)companiesgrownfromstart-uptoSMElevel• Bringtogether25companies(5foreachproject)thathavetherequiredtechnologiesatTRL5-7.• 15SMEs(2-5foreachproject)willhavedoubledigitgrowth• 15SMEs(2-5foreachproject)willstrengthentheirpositionbycollaboratingwithotherSMEs

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14 Appendix IX

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Implementation Roadmap on value chains and related pilot lines 195

14 Appendix IX

AppendixIX-PilotLine4Non mainstream Micro-Electro-Mechanical Systems and Architectures Description

Code Title of the actionPilot 4b (VC1) NonmainstreamMicro-Electro-MechanicalSystemsandArchitec-

turesB:CheapflexiblehybridorfullpolymerMEMSecosystemsSpecificChallengeAlthough the development of MEMS technologies enabled a huge range of possibilities, the range of com-mercial MEMS products is still relatively small (mainly accelerometers, digital micro-mirror devices, pressure sensors, and inkjet nozzles), even though the associated volumes are already quite large. It is expected to exhibit strong growth the coming years.Next generation MEMS will have to do more complicated things than the ones already on the market and in that sense be non-traditional. In this pilot the main challenge is to advance the state of the art of MEMS integrationwithcheapflexiblehybridorfullpolymerMEMSecosystems(i.e.non-mainstreamapplicationand integration by using multiple traditionally fabricated MEMS devices and integrating them on polymer substrates). This increase in integration complexity presents new demands on manufacturing tool capa-bilities, materials, sub-components, and hybrid integration processes and concepts. Because of the more complicated nature, characterization and metrology tools will face new challenges as well.ScopeProposals should address the development and demonstration in relevant industrial environments of reli-able manufacturing processes and metrology/control systems to produce product(s) that consist of multiple (traditionally) fabricated MEMS devices, supporting electronics, and other components and integrate them togetheron(flexible)polymersubstrates.Optionally,theusedMEMSdevicescanalsobefabricateddirectlyon top of a polymer substrate instead.For this topic, proposals should include an outline of the initial exploitation and business plans, which will be further developed in the proposed project.Activities within the pilot line will address a.o.:• Accommodationforprintedorganicelectronics,2DprintedMEMS,andlargeareaactivesurfacesas

well• Furtherdevelopmentoftechnologyforhybridintegration(processes,materials,testing,characterization,

metrology, sub-components, etc.)• DevelopmentofpilotproductstoshowcaseflexiblehybridsystemsAll in all, proposals should try to make us of the advantages polymers can have compared to silicone. Examplesareflexibility,transparency,lowerfabricationcost,etc.StartingTRL 4-5Target TRL 7ExpectedImpact

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Impacts:• Growthofqualityjobs• Moresustainableproduction(material,energy)• Increasecross-regioninteractionbetweenEUcompanies• BringtheavailableseedstogetherinapilotlinewiththepotentialtogiveEuropeacompetitiveedgeon

hybrid or full polymer MEMS ecosystems• IncreaseTRLofrelevantKETsto7(e.g.High-resolutionadditivemanufacturing)• NewEnablingTechnology→novelhigh-performanceproductspossiblewithassociatedeconomicgrowth• Newintegrationtechniquescanlowerrequiredinvestmentfornewproducts• AmountofnewbusinessperEUcalltopic:20Xcallbudget• IncreaseofindustrialleadershipinadvancedintegrationofMEMSandelectronics• AdvancedintegratedMEMSsolutionsmoreattainableforSMEs

Quantative targets:• 780M€ofnewbusinessgenerated(130M€perproject)• 5(1foreachproject)companiesgrownfromstart-uptoSMElevel• Bringtogether25companies(5foreachproject)thathavetherequiredtechnologiesatTRL5-7.• 15SMEs(2-5foreachproject)willhavedoubledigitgrowth15 SMEs (2-5 for each project) will strengthen their position by collaborating with other SMEs

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NANOfutures, European Technology Integrating and Innovation Platform on Nanotechnology