2013 annual report - Whitepages€¦ · 2013 annual report New South Wales Poisons Information...

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2013 annual report New South Wales Poisons Information Centre 13 11 26 Corner Hawkesbury Road and Hainsworth Street Locked Bag 4001 Westmead NSW 2145 Tel +61 2 9845 0000 Fax +61 2 9845 3489

Transcript of 2013 annual report - Whitepages€¦ · 2013 annual report New South Wales Poisons Information...

Page 1: 2013 annual report - Whitepages€¦ · 2013 annual report New South Wales Poisons Information Centre 13 11 26 Corner Hawkesbury Road and Hainsworth Street Locked Bag 4001 Westmead

2013 annual report

New South Wales

Poisons Information Centre

13 11 26

Corner Hawkesbury Road and Hainsworth Street

Locked Bag 4001 Westmead NSW 2145

Tel +61 2 9845 0000 Fax +61 2 9845 3489

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Table  of  Contents  

2013  Staff  Members  ............................................................................................................................  3  

Service  Details  .....................................................................................................................................  4  

Publications  ........................................................................................................................................  4  

Toxicovigilance  activities  ...................................................................................................................  10  

Clinical  governance  and  quality  assurance  activities  ..........................................................................  10  

Calls  received  per  month  for  2013  and  2012  ......................................................................................  11  

Victims  of  poisoning  ..........................................................................................................................  11  

Call  Characteristics  ............................................................................................................................  12  

Route  of  Exposure  .............................................................................................................................  12  

Persons  calling  the  Poisons  Information  Centre  .................................................................................  13  

Hourly  call  breakdown  ......................................................................................................................  13  

Histogram  based  on  time  of  calls  .......................................................................................................  14  

Handling  of  Calls  –  Adult  ...................................................................................................................  14  

Handling  of  Calls  –  Child  (<18  years)  ..................................................................................................  15  

Age  in  Years  of  Children  ....................................................................................................................  16  

Calls  based  on  Gender  .......................................................................................................................  16  

Call  type  ............................................................................................................................................  17  

Types  of  exposure  .............................................................................................................................  17  

Types  of  queries  ................................................................................................................................  17  

Calls  referred  from  health  phone  triage  services  ...............................................................................  18  

Substances  which  generate  the  most  calls  .........................................................................................  18  

Summary  of  calls  referred  to  medical  consultants  .............................................................................  18  

NB: Future annual reports will be reported on a financial year basis, starting from 1 July 2014 – 30 June 2015. An interim 6-month report for 1 January – 30 June 2014 will also be produced.

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2013  Staff  Members    

Administration    

A/Prof Naren Gunja, MB BS, MSc, FACEM, FACMT Medical Director

Prof Andrew Dawson MB BS, FRACP, FRCP (Edin) Senior Staff Specialist (Education)

Prof Nicholas Buckley MD, FRACP Senior Staff Specialist (Research)

Judith Kirby, B Pharm Manager (part-year)

Christa Lynch, B Pharm Manager (part-year) and Deputy Manager (part-year)

Lorraine Lum Secretary

 Senior  Poisons  Specialists  

 Jared Brown, B Pharm (Hons), MPH, GradDipClinEpi (Clin Tox)

Research and Audit Christine Cantlay, B Pharm

Recruitment Lorette Mack, B Pharm

Training Bina Sira, B Sc (Hons)

Standards

Additionally, 14 other poisons information specialists were involved in handling phone calls, most are pharmacists and three are medical scientists.

 

Medical  Consultants  

Dr Sam Alfred MB BS, FACEM Dr Jason Armstrong, MB BS, FACEM Dr Betty Chan, MB BS, FACEM, PhD Prof Nicholas Buckley, MD, FRACP

Dr Michael Downes, MB ChB, FACEM Dr Robert Dowsett, MB BS, FACEM

Prof Andis Graudins, MB BS PhD FACEM FACMT Dr Shaun Greene, MB ChB, MSc (Med Tox), FACEM

Dr Geoffrey Isbister, B Sc, MB BS, MD, FACEM Dr Zeff Koutsogiannis, MB BS, FACEM

Dr Mark Little, MB BS, FACEM, MPH&TM, DTM&H (Lon) Dr David McCoubrie, MB BS, FACEM

A/Prof Lindsay Murray, MB BS, FACEM Dr Colin Page, MBChB, FACEM, M Med Sc (Clin Epid)

Dr Jessamine Soderstrom, MB BS, FACEM

Fellows  in  Training

Dr Angela Chiew BSc (Med), MB BS (Hons), FACEM Dr Dino Druda B Med Sc (Hons), MB BS, MRCP(UK),

FACEM, Grad Dip Clin Tox Dr Dushan Jayaweera MB BS (Hons), FACEM, Dip Tox

Dr Satish Mitter MB BS, FACEM, Dip Tox                  

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Service  Details   Hours  of  Operation  The New South Wales Poisons Information centre forms part of a national network of Poisons Information Centres that provides 24 hours per day, seven days a week coverage, including all holidays. Telephone  Access  The Poisons Information Centre can be reached on 13 11 26 which gives callers access to the Centre from anywhere in Australia for the cost of a local call (excluding mobile phones). Medical  Consultants  Medical Toxicology Consultants are provided to physician callers for unusual, complicated or severe poisoning cases. Each day, coverage is provided for both adult and paediatric poisonings. (This service is available 24 hours per day).

Publications      The NSW Poisons Centre is in a unique position to be able to collect data and co-ordinate research into clinical toxicology particularly for rare poisonings and poisoning involving agents newly introduced to the market. These activities contributed to the following publications during 2013: Journals   1. Rajapakse  B,  Neeman  T,  Dawson  AH  The  effectiveness  of  a  'train  the  trainer'  model  of  

resuscitation  education  for  rural  peripheral  hospital  doctors  in  Sri  Lanka.  Plos  One  November  2013  DOI:  10.1371/journal.pone.0079491  

2. Pearson  M,  Zwi  AB,  Buckley  NA,  Manuweera  G,  Fernando  R,  Dawson  AH,  McDuie-­‐Ra  D.  Policymaking  'under  the  radar':  A  case  study  of  pesticide  regulation  to  prevent  intentional  poisoning  in  sri  lanka.  Health  Policy  Plan  2013,  Dec  20.  

3. Senarathna  L,  Buckley  NA,  Dibley  MJ,  Kelly  PJ,  Jayamanna  SF,  Gawarammana  IB,  Dawson  AH.  "Effect  of  a  Brief  Outreach  Educational  Intervention  on  the  Translation  of  Acute  Poisoning  Treatment  Guidelines  to  Practice  in  Rural  Sri  Lankan  Hospitals:  A  Cluster  Randomized  Controlled  Trial."  PloS  one  8,  no.  8  (2013):  doi:10.1371/journal.pone.0071787.  

4. Weerasinghe  M,    Pearson  M,    Peiris  R,    Dawson  A.H,    Eddleston  M,    Jayamanne  S,    Agampodi  S,    Konradsen  F  The  role  of  private  pesticide  vendors  in  preventing  access  to  pesticides  for  self-­‐poisoning  in  rural  Sri  Lanka.  Injury  Prevention    (June  2013)  

5. Senarathna  L,  Hunter  C,  Dawson  A.H,  Michael  J.  Dibley  MJ      Social  Dynamics  in  Sri  Lankan  Rural  Hospitals:  Revelations  from  Self-­‐poisoning  Cases.  Qualitative  Health  Research  (October  2013)  

6. Carter  GL,  Clover  K,  Whyte  IM,  Dawson  A.H,  D’Este  C.    2013,  Postcards  from  the  EDge:  5-­‐year  outcomes  of  a  randomised  controlled  trial  for  hospital-­‐treated  self-­‐poisoning.  British  Journal  of  Psychiatry.  2013  May;202(5):372-­‐80  

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7. Buckley  NA,  Dawson  A.H.  The  intralipid  genie  is  out  of  the  bottle-­‐spin  and  wishful  thinking.  Anaesth  Intensive  Care.  2013  Mar;41(2):154-­‐6  

8. Basher  A,  Rahman  SH,  A.  Ghose  A,  Arif  SM,  M.  A.  Faiz  MA,  Dawson,  A.H.,  2013,  Phase  II  study    of  Magnesium  Sulfate  in  acute  Organophosphate  pesticide  poisoning  Clinical  Toxicology  (Philadelphia,  Pa.),  51(1),  pp  35–40  

9. Dawson,  A  H,  and  M  F  Wilks.  "With  the  Benefit  of  Hindsight:  Trials  Using  Retrospective  Controls  Versus  Randomized  Controlled  Trials  in  Clinical  Toxicology."  Clinical  toxicology  (Philadelphia,  Pa.)  (2013)doi:10.3109/15563650.2013.821130.  

10. Dawson,  AH.  "Comment  on  Editorial;  Best  Research  for  Low  Income  Countries."  Asia  Pacific  Journal  of  Medical  Toxicology  2,  no.  2  (2013):  76  

11. Johnston  CI,  Brown  SG,  O'Leary  MA,  Currie  BJ,  Greenberg  R,  Taylor  M,  Isbister  GK;  for  the  ASP  investigators.  Mulga  snake  (  Pseudechis  australis  )  envenoming:  a  spectrum  of  myotoxicity,  anticoagulant  coagulopathy,  haemolysis  and  the  role  of  early  antivenom  therapy  –  Australian  Snakebite  Project  (ASP-­‐19).  Clinical  Toxicology  2013;  51(5):417-­‐24.  

12. Gulati  A,  Isbister  GK,  Duffull  SB.  Effect  of  Australian  elapid  venoms  on  blood  coagulation  (ASP-­‐17).  Toxicon  2013;  61C:94-­‐104.  

13. Cubitt  M,  Armstrong  J,  McCoubrie  D,White  J,  Williams  V,  Isbister  GK.  Point-­‐of-­‐care  testing  in  snakebite.  Emergency  Medicine  Australasia  2013;25:372–374.  

14. Pearson  M,  Zwi  AB,  Manuweera  G,  Buckley  NA,  Fernando  R,  Dawson  AH,  McDuie-­‐Ra  D.  Policymaking  ‘under  the  radar’:    a  case  study  of  pesticide  regulation  to  prevent  intentional  poisoning  in  Sri  Lanka.  Health  Policy  and  Planning  2013;  Dec  20.  [Epub  ahead  of  print]  IF:3.056  

15. Isbister  GK,  Buckley  NA,  Page  CB,  Brown  SGA.  A  randomised  controlled  trial  of  fresh  frozen  plasma  for  venom  induced  consumption  coagulopathy  in  Australian  snakebite  (ASP-­‐18).    Journal  of  Thrombosis  and  Haemostasis  2013;11(7):1310-­‐8.  IF:6.081  

16. Konickx  LA,  Worek  F,  Jayamanne  S,  Thiermann  H,  Buckley  NA,  Eddleston  M.  Reactivation  of  plasma  butyrylcholinesterase  by  pralidoxime  chloride  in  patients  poisoned  by  WHO  Class  II  toxicity  organophosphorus  insecticides.  Toxicological  Sciences2013;136(2):274-­‐83.  IF:4.7  

17. Wunnapuk  K,    Liu  X,  Peake  P,  Gobe  G,  Endre  Z,  Grice  JE,  Roberts  MS,  Buckley  NA.  Renal  biomarkers  predict  nephrotoxicity  after  paraquat.  Toxicology  Letters  2013;222:280-­‐288.  IF:3.145  

18. Senarathna  L,  Buckley  NA,  Jayamanna  SF,  Kelly  P,  Dibley  MJ,  Dawson  AH.    Effect  of  a  Brief  Outreach  Educational  Intervention  on  the  Translation  of  Acute  Poisoning  Treatment  Guidelines  to  Practice  in  Rural  Sri  Lankan  Hospitals:  A  Cluster  Randomized  Controlled  Trial.  PLoS  ONE  2013;8(8):  e71787.  IF:3.730  

19. Isbister  GK,  Maduwage  K,  Shahmy  S,  Scorgie  F,  O’Leary  MA,  Mohamed  F,  Abeysinghe  C,  Karunathilake  H,  Ariaratnam  CA,Buckley  NA.  Poor  diagnostic  utility  of  the  20  minute  whole  blood  clotting  test  (WBCT20)  for  viper  envenoming.  Quarterly  Journal  of  Medicine  2013;  106(10):925-­‐32.  IF:2.361  

20. Roberts  DM,  Hall  MJ,  Falkland  MM,  Strasser  SI,  Buckley  NA.  Amanita  phalloides  poisoning  and  treatment  with  silibinin  in  the  Australian  Capital  Territory  and  New  South  Wales.  Medical  Journal  of  Australia  2013;198(1):43-­‐47.    IF:2.853  

21. Roberts  D,  Buckley  NA.    Paraquat/Diquat  poisoning  in:  In:  UpToDate,  Basow,  DS  (Ed),  UpToDate,  Waltham,  MA;  latest  version  23rd  May  2013.  

22. Isbister  GK,  Page  CB,  McCoubrie  D,  Green  S,  Brown  SGA,  Buckley  NA.  Treatment  of  snake  bite  in  Australia:  a  practical  approach  to  diagnosis  and  treatment.  Medical  Journal  of  Australia  2013;199:763–768.    IF:2.853  

23. Pianta  TJ,  Buckley  NA,  Peake  PW,  Endre  ZH.  The  clinical  use  of  biomarkers  for  toxicant-­‐induced  acute  kidney  injury  (ToxAKI).Biomarkers  in  Medicine  2013;  7(3):441-­‐56.  IF:  3.217  

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24. Buckley  NA,  Dawson  AH.  The  intralipid  genie  is  out  of  the  bottle  –  Spin  &  wishful  thinking.  Anaesthesia  Intensive  Care2013;  41(2):154-­‐156.  IF:  1.396  

25. Buckley  NA,  Faunce  T.    Trials  and  Tribulations  in  the  Removal  of  Dextropropoxyphene  from  the  Australian  Register  of  Therapeutic  Goods.    Medical  Journal  of  Australia  2013;  199(4):257-­‐260.    IF:2.853  

26. Buckley  NA,  Whyte  IM.  Antivenom  (snakebite  treatment  in  rural  and  remote  areas).    Australian  Prescriber  2013;  1:4.  IF:  0.831  

27. Buckley  NA,  Juurlink  DN.  Carbon  monoxide  treatment  guidelines  must  acknowledge  the  limitations  of  the  existing  evidence.American  Journal  of  Respiratory  and  Critical  Care  Medicine  2013;  187(12):1390.    IF:11.041  

28. Isbister  GK,  Buckley  NA,  Brown  SGA.  Tiger  snake  (Notechis  spp)  envenoming:  Australian  Snakebite  Project  (ASP-­‐13).  Medical  Journal  of  Australia    2013;198(4):194-­‐5.  IF:2.853    

29. Brown  JA,  Buckley  NA.  Carbon  monoxide  death  and  toxicity  from  charcoal  briquettes.  Medical  Journal  of  Australia2013;198(2):86.  IF:2.853  

30. Brown  JA,  Buckley  NA.  Toxicity  from  bodybuilding  supplements  and  ‘legal  highs’  containing  1,3-­‐dimethylamylamine  (DMAA).Medical  Journal  of  Australia  2013;  198(8):414-­‐5.  IF:2.853  

31. Brown  JA.  Clinical  Toxicology  and  Poisons  Information  Centres  –  an  Australian  pharmacist’s  experience.  Journal  of  Pharmacy  Practice  and  Research.  2013;  43  (1):  81-­‐2.  

32. Brown  JA.  Medicinal  mishap:  incorrectly  dropped  in  the  eye.  Australian  Prescriber.  2013;  36  (2):  56-­‐7.    

33. Lubman  D,  Peacock  A,  Droste  N,  Pennay  A,  Miller  P,  Bruno  R,  Lloyd  B,  Hyder  S,  Roxburgh  A,  Wadds  P,  Tomsen  S,  Brown  J.  Alcohol  and  Energy  Drinks  in  NSW.  Turning  Point  Alcohol  and  Drug  Centre,  Melbourne.  April  2013.    

34. Li,  E.,  Gunja,  N.  (2013).  Illicit  drug  overdose  -­‐  Prevalence  and  acute  management.  Australian  Family  Physician,  42(7),  481-­‐485.  

35. Gunja,  N.  (2013).  In  the  Zzz  Zone:  The  Effects  of  Z-­‐Drugs  on  Human  Performance  and  Driving.  Journal  of  Medical  Toxicology,  9(2),  163-­‐171.  

36. Gunja,  N.  (2013).  The  Clinical  and  Forensic  Toxicology  of  Z-­‐drugs.  Journal  of  Medical  Toxicology,  9(2),  155-­‐162.  

Presentations    1. Dawson  AH.  Therapeutic  implications  of  relative  toxicity  of  SSRI  and  SNRI  

antidepressants  (Invited  Speaker)  Sri  Lanka  College  of  Psychiatrists  Annual  Academic  Sessions.  Kandy  Sri  Lanka,  March  2  2013  

2. Dawson  AH.  Establishing  a  Clinical  Research  Centre.  (Invited  Speaker)  Asia  Pacific  Association  of  Medical  Toxicology,  Dubai,  November  21  2013  

3. Dawson  AH.  Opening  our  data.  (Plenary  Speaker)  Asia  Pacific  Association  of  Medical  Toxicology,  Dubai,  November  22  2013  

4. Dawson  AH.  Tropical  Toxicology.  Invited  Speaker.  Social  Media  and  Acute  Critical  Care  Conference.  Sydney  May  2013  

5. Dawson  AH.  Acute  toxicology:  potential  roles  in  setting  environmental  priorities.    Invited  Speaker  Korea    International  Union  of  Toxicology  Congress  June  2013  

6. Dawson  AH.  Just  how  poisonous  are  SSRIs?  Invited  Keynote  Copenhagen  EAPCCT  May  2013  

7. Senarathna  L,  Guruge  D,  Gawararammana  I,  Bandara  P,  Dawson  A.  First  aid  practices  for  acute  poisoning  and  snakebite  patients  in  Sri  Lanka-­‐  findings  from  a  community  study.  APAMT  12th  Congress  Dubai  November  2013  

8. Pushpakumar  PHGJ,  Tennakoon  SUB,  Adikari  AMP,  Dawson  AH,  Abeysinghe  R.  Impact  of  life-­‐skills,  help  seeking  ability  nad  mental  health  on  acute  deliberate  self  poisoning  in  

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Kurunegala  District,  Sri  Lanka:  A  case  control  study.  APAMT  12th  Congress  Dubai  November  2013  

9. Buckley  N,  Dawson  A,  Whyte  I,  Isbister  G.  25  years  of  self-­‐poisoning  in  Newcastle,  1987-­‐2011.  APAMT  12th  Congress  Dubai  November  2013  

10. Pathmeswaran  A,  Kasturiratne  A,  Gunawardena  NK,  Wijayawickrama  BA,  Jayamanne  S,  Isbister  G,  Dawson  A,  de  Silva  HJ.  Community  incidence  of  snakebite  in  Sri  Lanka.  APAMT  12th  Congress  Dubai  November  2013  

11. Senarathna  L,  Hunter  C,  Dibley  M,  Buckley  N,  Jayamanne  S,  Dawson  A.  percetption  of  community  expectations  blocks  policy  into  practice  translation  in  poisoning  treatment  in  Sri  Lankan  rural  hospitals.  APAMT  12th  Congress  Dubai  November  2013  

12. Ariyananda  P,  Palangasinghe  C,  Perera  B,  Abeygunawardena  D,  Dawson  A.  prospective  observational  study  of  clinical  features  of  adults  with  glyphospate  poisoning  in  southern  Sri  Lanka.  APAMT  12th  Congress  Dubai  November  2013  

13. Buckley  NA.    Beware  of  false  dichotomies  -­‐  adopting  quantified  risk  assessment  into  clinical  toxicology  practice.  Asia  Pacific  Association  of  Medical  Toxicology  (APAMT)  meeting,  Dubai,  November  2013.  

14. Buckley  NA.  Problems  with  estimating  the  effectiveness  of  treatments  for  organophosphorus  poisoning  &  Paraquat  -­‐  What  to  do?  (seminar).  Preventive  Medicine,  Korea  University,  Seoul.  July  3rd,  2013.      

15. Buckley  NA.    Paracetamol  poisoning.  SMACC  Conference,  Sydney,  March  11-­‐13  2013  16. Wijerathna  PATM,  Dissanayake  D,  Fahim  M,  Gawarammana  IB,  Buckley  

NA.  Identification  of  Novel  Urinary  Biomarkers  as  Surrogates  of  Acute  Kidney  Injury  Following  Human  Self-­‐Poisoning  With  a  New  Laundry  Detergent  In  Southern  Sri  Lanka.Asia  Pacific  Association  of  Medical  Toxicology  (APAMT)  meeting,  Dubai,  November  2013.  

17. Fahim  M,  Gawarammana  IB,  Buckley  NA.  Mechanisms  underlying  early  rapid  increases  in  creatinine  in  paraquat  poisoning.  Asia  Pacific  Association  of  Medical  Toxicology  (APAMT)  meeting,  Dubai,  November  2013.  

18. Buckley  NA,  Dawson  AH,  Whyte  IM,  Isbister  GK.    Twenty  five  years  of  poisoning  in  Newcastle.  Asia  Pacific  Association  of  Medical  Toxicology  (APAMT)  meeting,  Dubai,  November  2013.  

19. Konickx  LA,  Worek  F,  Jayamanne  S,  Thiermann  H,  Buckley  NA,  Eddleston  M.  Reactivation  of  plasma  butyrylcholinesterase  by  pralidoxime  chloride  in  patients  poisoned  by  WHO  Class  II  toxicity  organophosphorus  insecticides.  Asia  Pacific  Association  of  Medical  Toxicology  (APAMT)  meeting,  Dubai,  November  2013.  

20. Isbister  GK,  Page  CB,  Buckley  NA,  Fatovich  D,  Pascu  O,  MacDonald  S,  Calver  LA,  Brown  SGA.  Randomised  controlled  trial  of  intravenous  antivenom  versus  placebo  for  the  treatment  of  latrodectism  –  the  second  redback  antivenom  evaluation  (RAVE-­‐  II)  study.  Asia  Pacific  Association  of  Medical  Toxicology  (APAMT)  meeting,  Dubai,  November  2013.  

21. Pearson  SA,  Abrahamowicz  M,  Srasuebkul  P,  Buckley  N.  Antidepressant  treatment  (ADT)  following  a  cancer  diagnosis:  Investigation  in  a  cohort  of  older  patients.  International  Conference  on  Pharmacoepidemiology  (ISPE)  August  25-­‐28,  2013,  Montreal,  Canada.  

22. Langton  JM,  Srasuebkul  P,  Buckley  N,  Pearson  SA.  Medicines  in  the  last  12  months  of  life:  Observations  in  a  cohort  of  elderly  patients.  International  Conference  on  Pharmacoepidemiology  (ISPE).  August  25-­‐28,  2013,  Montreal,  Canada.  

23. Pianta  TJ,  Chin  MT,  Peake  PW,  Buckley  NA,  Pickering  JW,  Endre  ZH.  Plasma  cystatin  C  is  elevated  in  the  absence  of  acute  kidney  injury  following  cisplatin  with  contemporary  antiemetics.  ANZSN  49th  Annual  Scientific  Meeting.  Nephrology2013;  18  (Supp.  1):41.  

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24. Pianta  TJ,  Peake  PW,  Buckley  NA,  Kelleher  M,  Pickering  J,  Endre  ZH.    Urinary  Clusterin  Predicts  graft  Recovery  Within  Four  Hours  Of  Transplantation.    ANZSN  49th  Annual  Scientific  Meeting.  Nephrology  2013;18  (Supp.  1):43  

25. Succar  L,  Peake  PW,  Pianta  TJ,  Buckley  NA,  Endre  ZH.    Urinary  biomarker  KIM-­‐1  rises  earlier  than  NGAL  in  experimental  aristolochic  acid  nephropathy.    ANZSN  49th  Annual  Scientific  Meeting.  Nephrology  2013;18(Supp.  1):53  

26. Wunnapuk  K,  Mohammed  F,  Gawarammana  I,  Liu  X,  Verbeeck  RK,  Buckley  NA,    Roberts  MS,  Musuamba  FT.  Population  analysis  of  paraquat  toxicokinetics  in  poisoning  patients.  Population  analysis  group  of  Europe  (PAGE)  meeting  Glasgow  June  2013.  

27. Mohamed  F,  Endre  Z,  Shihana  F,  Peake  P,  Buckley  N.    Novel        acute        kidney        injury      (AKI)      biomarkers      in      early      diagnosis      of      glyphosate      surfactant      herbicide      (GSH)      poisoning.    World  Congress  of  Nephrology.  Hong  Kong  June  2013.  

28. Chiew  AL,  Brown  J,  Chan  BSH,  Buckley  NA.  Puberty  blues  -­‐  Copper  salt  exposures  in  Australian  schools.  European  Association  of  Poisons  Centres  &  Clinical  Toxicology  Scientific  meeting,  Copenhagen  2013.    Clinical  Toxicology  2013;51(4):360  

29. Chan  BSH,  Chakir,  B,  Sivanesan  A,  Gunja  N,  Brown  J,  Buckley  NA.  Metformin  induced  lactic  acidosis  reported  to  the  New  South  Wales  Poisons  Information  Centre  European  Association  of  Poisons  Centres  &  Clinical  Toxicology  Scientific  meeting,  Copenhagen  2013.  Clinical  Toxicology  2013;51(4):364.  

30. Brown  JA.  Children  and  Medicine  Adverse  Events  (invited  speaker).  NSW  Pharmacy  Guild  National  Convention  and  Exhibition,  June  21-­‐23  2013.  

31. Green  JL,  Desel  H,  Milanesi  G,  Sesana  F,  Brown  JA,  Gunja  N,  Kupferschmidt  H,  De  Vries  I,  Campbell  A,  Thomas  SHL,  Thompson  JP,  Severtson  G,  Poppish  L,  Gmerek  B,  Dart  RC.  Unintentional  pediatric  opioid  exposures  as  reported  to  the  Global  Toxicosurveillance  Network  (GTNet)  from  2008–2010.  European  Association  of  Poisons  Centres  and  Clinical  Toxicologists  Congress,  May  28-­‐31  2013.  Abstract  available  in:  Green,  et  al.  Clin  Toxicol  2013;51:339.  

32. Brett  J,  Brown  JA,  Dawson  A.  Clenbuterol  toxicity:  NSW  Poisons  Information  Centre  Experience  (oral  presentation).  Toxicology  and  Poisons  Network  Australasia  Scientific  Meeting,  May  2-­‐4  2013.  

33. Brown  JA.  Poisons  centres  and  public  health.  Public  Health  Trainees  Meeting,  Sydney.  22  May  2013.  

34. Gunja  N.  FACTA  Conference,  Sydney  2013.  Performance  impairment  from  Z-­‐drugs  –  Invited  speaker  

35. Gunja  N.  ACEM  Annual  Scientific  Meeting,  Adelaide  2013.  SIMWARS  Facilitator,  Toxicology  workshop  instructor  

36. Dutch  North  Sea  Emergency  Medicine  Conference,  Amsterdam  NL  2013.  Antidote  Update  –  Invited  speaker,  Toxic  cardiac  arrest  –  workshop  instructor  

37. Gunja  N.  ACMT  Scientific  Meeting,  San  Juan,  Puerto  Rico  2013:  Sedation  of  the  agitated  patient  –  Invited  speaker,  Physostigmine  in  psychotropic  anti-­‐cholinergic  poisoning  –  Poster  

38. Gunja  N.  AAFS  (Australian  Academy  of  Forensic  Sciences),  Sydney  2013:  The  Art  of  Poisoning  –  Keynote  Speaker  

39. Gunja  N.  Paediatric  GP  Update,  CHW  Sydney.  Lead  poisoning  –  invited  speaker      

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Committees  &  Boards    Staff at the NSW Poisons Information Centre provided expertise to the following local, regional, national and international committees and boards:  Jared Brown

• TGA  Medicine  Labelling  and  Packaging  Review  Group   Prof Nicholas Buckley

• Chair  of  the  Editorial  Advisory  Board  of  the  Australian  Medicines  Handbook.  • Member  of  the  Australian  Advisory  Committee  on  the  Safety  of  Medicines  (ACSOM).  • Member  of  Editorial  boards:  Australian  Therapeutic  Guidelines  -­‐  Toxicology  and  

Wilderness,  TOXINZ  &  Hypertox  (electronic  databases  of  poisoning  information),  the  journals  Drug  Safety  (0114-­‐5916),  Clinical  Toxicology  (0009-­‐9309),  and  Australian  Prescriber  

• President-­‐elect  of  the  Asia  Pacific  Association  of  Medical  Toxicology.  

Prof Andrew Dawson

• Advisory  Committee  on  Medicines  Scheduling  (acting  Chair)  • Advisory  Committee  on  Chemicals  Scheduling(acting  Chair)  • Board  Member  Australasian  Society  of  Clinical  and  Experimental  Pharmacologists  

and  Toxicologists  • Editorial  Board  Ceylon  Medical  Journal  • Editorial  Board  Journal  of  the  Ceylon  College  of  Physicians  • Senior  Editorial  Board  Journal  of  Clinical  Toxicology  • Editorial  Board    Journal  of  Indian  Society  of  Toxicology  • Senior  Editorial  Board  WikiTox  • Director  South  Asian  Clinical  Toxicology  Collaboration  

Dr Naren Gunja

• ACEM  Primary  Examination  Committee  –  Chair  of  Pharmacology  • ACMT  International  Committee  –  Regional  ambassador    • ACMT  Public  Affairs  Committee  –  Member  

Awards   Prof Andrew Dawson

• NHMRC  Practitioner  Fellowship  • 2013  American  College  of  Medical  Toxicology  Service  Award  for  Outstanding  

Contribution  in  Medical  Toxicology  Education.  Awarded  at  ACMT  Annual  Scientific  Meeting,  Puerto  Rico  March  17  2013  

• 2013  Asia  Pacific  Association  of  Medical  Toxicology,  Honorary  Fellow  

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Toxicovigilance  activities   Research and audit are key to the public health focus of the NSW Poisons Information Centre. Over 2013, NSWPIC has provided data as follows:

• Panadol  faulty  syringe  recall  cases  • Laundry  product  exposures  to  ACCC,  with  an  emphasis  on  laundry  pods  • Prescription  drug  abuse  data  (prescription  opioids  and  stimulants)  to  Global  

Toxicology  Network  collaboration  • Call  data  pertaining  to  accidental  carbon  monoxide  exposures  from  burning  charcoal  

products  was  provided  to  the  Australian  Competition  and  Consumer  Commission  (ACCC).  

• Call  data  pertaining  to  paediatric  laundry  detergent  pod  exposures  was  provided  as  part  of  an  ongoing  national  PIC  study.    

• Therapeutic  error  call  data  was  provided  to  QLD  PIC,  for  presentation  at  the  Society  of  Hospital  Pharmacists  of  Australia  NationalMedicines  Management  Conference.    

• Call  data  pertaining  to  Lye  water  exposures  was  provided  to  South  Australia’s  Public    Health  division.    

• Mushroom  exposures  was  provided  to  the  Australia-­‐wide  study    ‘Poisoning  due  to  fungi  ingestion  –  a  retrospective  study  of  cases  reported  to  Australian  Poisons  Information  Centres’.    

• Provision  of  data  and  recruitment  commenced  through  NSWPIC  for  Australian  Toxicology  Monitoring  (ATOM)  studies  on  paracetamol  and  digoxin  

• Analysis  of  National  Coronial  Information  System  for  deaths  from  pesticides  • Australian  Government  Department  of  Health  was  provided  with  data  on  exposures  

to  OxyElite  • Australian  Red  Cross  Blood  Service  was  provided  with  data  on  iron  ingestions  • Collaboration  with  Honours  student  at  the  Faculty  of  Pharmacy,  The  University  of  

Sydney  on  drug  related  problems  from  over  the  counter  medicines  in  young  children  • Provision  to  the  Therapeutic  Goods  Administration  on  dosing  errors  with  

paracetamol  and  ibuprofen  • Intravenous  paracetamol  dosing  errors  provided  to  NSW  Therapeutic  Advisory  

Group  • Data  on  synthetic  cannabinoid  exposures  and  illicit  drug  exposures  supplied  to  NSW  

Health  • Laundry  pod  exposures  to  Unilever  • E-­‐cigarette  exposures  to  NSW  Health  • Mushroom  exposures  to  SA  Health  • Calls  relating  to  mercury  from  South  Eastern  Sydney  Local  Health  District,  Public  

Health  Unit  • Call  data  pertaining  to  infant  colic  mixtures  prepared  by  compounding  pharmacies  

was  provided  to  the  Pharmacy  Board  of  Australia,  care  of  VICPIC  

Clinical  governance  and  quality  assurance  activities   All poisons information specialist calls were peer-reviewed by another poisons information specialist. Cases which clinical toxicologists are consulted on are circulated to all NSWPIC clinical toxicologists and poisons information specialists for review.

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Calls  received  per  month  for  2013  and  2012  

Month   2013   2012  January     9118   9823  February   8655   9009  March   9238   9511  April   8154   8400  May   8254   8893  June   8057   8419  July   8351   8384  August   8729   8969  September   8710   8934  October   8928   9153  November   8597   9578  December   8914   9619  

Victims  of  poisoning    

Adults:  46250  Children:  44964  Animals:    2066  

 

50%  

48%  

2%  

Adults  

Children  

Animals  

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Call  Characteristics  Calls  by  Geographic  Source  Calls are received from all over the country at the New South Wales Poisons Information Centre. A breakdown of these calls appears below. The calls taken from interstate (other than Tasmania and the Australian Capital Territory) are done so during after-hours night shifts.

State   Number  of  calls   %  of  calls  New  South  Wales   68615   66.2  Queensland   9354   9.0  Victoria   7896   7.6  Unknown   5425   5.2  Tasmania   3285   3.2  Australian  Capital  Territory   3077   3.0  South  Australia   2936   2.8  Western  Australia   2733   2.6  Northern  Territory   288   0.3  International   96   0.1  TOTAL   103705    

In addition to calls taken by NSW PIC, the other three PICs handled the following call volumes:

State   Number  of  calls  Victoria   38740  Western  Australia   38261  Queensland   30734  

Route  of  Exposure  

Calls  involving  route   Number  of  calls   %  of  calls  Ingestion   62944   80.5  Ocular   4722   6.0  Dermal   3576   4.6  Inhalation/Nasal   3095   4.0  Bite/Sting   3034   3.9  Parenteral  (eg  injected)   645   0.8  Unknown/Other   215   0.3  

NB: Multiple routes of exposure are possible  

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Persons  calling  the  Poisons  Information  Centre  

Caller  background   Number  of  calls   %  of  calls  Family   44186   43.6  Self   21609   21.3  Doctor   12068   11.9  Nurse   6578   6.5  Unknown   5315   5.2  Carer   2533   2.5  Ambulance   2487   2.5  Group  Home   2083   2.1  Friend   2006   2.0  Other   1259   1.2  Pharmacist   482   0.5  Counselling  service   364   0.4  Vet   325   0.3  Other  medical   100   0.1  

Hourly  call  breakdown  

Time   Number  of  calls   %  of  calls  Midnight  –  0100   2081   2.0  0100  –  0200   1733   1.7  0200  –  0300   1352   1.3  0300  –  0400   1125   1.1  0400  –  0500   818   0.8  0500  –  0600   815   0.8  0600  –  0700   1992   1.9  0700  –  0800   4839   4.7  0800  –  0900   5924   5.7  0900  –  1000   6268   6.0  1000  –  1100   5467   5.3  1100  –  1200   4460   4.3  1200  –  1300   4146   4.0  1300  –  1400   4087   3.9  1400  –  1500   4465   4.3  1500  –  1600     4333   4.2  1600  –  1700   5293   5.1  1700  –  1800   5752   5.5  1800  –  1900   6055   5.8  1900  –  2000   6247   6.0  2000  –  2100     6423   6.2  2100  –  2200   7414   7.1  2200  –  2300     7450   7.2  2300  -­‐  MIdnight   5162   5.0  

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Histogram  based  on  time  of  calls  

NB: There are 7 shifts per fortnight Midnight – 0600 which are handled by interstate PICs

Handling  of  Calls  –  Adult  

Handling   Number  of  calls   %  of  calls  At  GP  surgery   486   1.2  Referred  to  GP   1101   2.6  Referred  to  Hospital   5442   13.0  In  Hospital   10531   25.2  Other   1405   3.4  Stay  at  home   15554   37.2  Unknown   10   0.0  

0  1000  2000  3000  4000  5000  6000  7000  8000  

Midnight  –

 0100  

0100  –  0200  

0200  –  0300  

0300  –  0400  

0400  –  0500  

0500  –  0600  

0600  –  0700  

0700  –  0800  

0800  –  0900  

0900  –  1000  

1000  –  1100  

1100  –  1200  

1200  –  1300  

1300  –  1400  

1400  –  1500  

1500  –  1600    

1600  –  1700  

1700  –  1800  

1800  –  1900  

1900  –  2000  

2000  –  2100    

2100  –  2200  

2200  –  2300    

2300  -­‐  MIdnight  

1%   3%  

16%  

31%  

4%  

45%  

0%   At  GP  surgery  

Referred  to  GP  

Referred  to  Hospital  

In  Hospital  

Other  

Stay  at  home  

Unknown  

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Handling  of  Calls  –  Child  (<18  years)  

Handling   Number  of  calls   %  of  calls  At  GP  surgery   350   0.8  Referred  to  GP   324   0.8  Referred  to  Hospital   2496   6.0  In  Hospital   5124   12.2  Other   936   2.2  Stay  at  home   32628   77.9  Unknown   8   0.0  

 

1%   1%  

6%  

12%  2%  

78%  

0%  At  GP  surgery  

Referred  to  GP  

Referred  to  Hospital  

In  Hospital  

Other  

Stay  at  home  

Unknown  

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Age  in  Years  of  Children  

Age   Number  of  calls   %  calls  <1   4282   10.8  1   10747   26.3  2   9616   23.6  3   4628   11.3  4   2281   5.6  5   1342   3.3  6   884   2.2  7   681   1.7  8   552   1.4  9   377   0.9  10   415   1.0  11   337   0.8  12   397   1.0  13   538   1.3  14   844   2.1  15   1054   2.6  16   917   2.2  17   791   1.9  

Calls  based  on  Gender  

Gender   Number  of  calls   %  of  calls  Female   46144   53.4  Male   39256   45.4  Unknown   1042   1.2  

0  

2000  

4000  

6000  

8000  

10000  

12000  

<1   1   2   3   4   5   6   7   8   9   10   11   12   13   14   15   16   17  

Num

ber  o

f  calls  

Age  in  years  

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Call  type  

Call  Type   Number  of  calls   %  of  calls  Exposure   72964   70.4  Query   20031   19.3  Re-­‐call   5052   4.9  Unknown   5658   5.5  

Types  of  exposure  

Exposure  Type   Number  of  calls   %  calls  Accidental   48269   60.9  Adverse  reaction   1033   1.3  Deliberate  self-­‐poisoning   12354   15.6  Environmental   60   0.1  Food  Poisoning   83   0.1  Intentional:  other   1410   1.8  Occupational   143   0.2  Other   62   0.1  Other/Unknown   197   0.2  Pregnancy   51   0.1  Recreational   994   1.3  Therapeutic  error   13542   17.1  Unknown   229   0.3  Work  place   813   1.0  

Types  of  queries  

Query  Type   Number  of  calls   %  calls  Breastfeeding   567   2.1  Drug  Information   10573   39.2  Environmental   124   0.5  Inappropriate  call-­‐referred   885   3.3  Medical   930   3.4  Occupational   35   0.1  Poisons  info   7421   27.5  Pregnancy   556   2.1  Prevention/safety   643   2.4  Wrong  number/hoax  call/phone  line  issue  

 5246   19.4  

Page 18: 2013 annual report - Whitepages€¦ · 2013 annual report New South Wales Poisons Information Centre 13 11 26 Corner Hawkesbury Road and Hainsworth Street Locked Bag 4001 Westmead

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Calls  referred  from  health  phone  triage  services  

Phone  triage  referral  sources  

Number  of  calls   %  of  calls  

Healthdirect  Australia  (all  states  and  territories  except  Victoria  and  Queensland)  

2783   2.7  

Nurse  on  Call  (VIC)   969   0.9  13HEALTH  (QLD)   647   0.6  MiHealth   153   0.1  GP  Assist   90   0.1  

Substances  which  generate  the  most  calls  The following table shows the Top 10 substances that generated the most calls to the New South Wales Poisons Information Centre in 2013. The full list of exposures by substance in adults and children is available on request. Substance   Number  of  calls*  

Paracetamol-­‐containing  product   7243  

Ibuprofen-­‐containing  product  (systemic)   2567  

Ethanol   1716  

Quetiapine   1594  

Paracetamol  +  narcotic  combination  analgesic   1381  

Diazepam   1317  

Spiders   1249  

Bleach  (hypochlorite-­‐based)   1165  

Desiccant  (silica  gel)   1037  

Cleaners  (all-­‐purpose/hard-­‐surface)   1003  

*Number of unique calls reported, ie calls which generated call-backs (re-calls) are excluded  

Summary  of  calls  referred  to  medical  consultants   NSWPIC referred 1715 calls to a medical toxicologist. Many calls involve multiple substances. The full list of substances involved in calls to medical toxicologists is available on request.