1442 W...Over 0.2 mm of height is required to penetrate epidermal layers. (b) Conceptual...

3
2 The University of Tokyo, JAPAN Figure 1 (a) A microneedle-based drug-delivery patch. Over 0.2 mm of height is required to penetrate epidermal layers. (b) Conceptual illustration of inclined/rotated UV lithography to obtain microneedle arrays. The fabrication process needs single UV exposure. 1442 978-0-9798064-8-3/μTAS 2015/$20©15CBMS-0001 19 th International Conference on Miniaturized Systems for Chemistry and Life Sciences October 25-29, 2015, Gyeongju, KOREA

Transcript of 1442 W...Over 0.2 mm of height is required to penetrate epidermal layers. (b) Conceptual...

Page 1: 1442 W...Over 0.2 mm of height is required to penetrate epidermal layers. (b) Conceptual illustration of inclined/rotated UV lithography to obtain microneedle arrays. The fabrication

2 The University of Tokyo, JAPAN

Figure 1 (a) A microneedle-based drug-delivery patch. Over 0.2 mm of height is required to penetrate

epidermal layers. (b) Conceptual illustration of inclined/rotated UV lithography to obtain microneedle

arrays. The fabrication process needs single UV exposure.

1442978-0-9798064-8-3/µTAS 2015/$20©15CBMS-0001 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences October 25-29, 2015, Gyeongju, KOREA

Page 2: 1442 W...Over 0.2 mm of height is required to penetrate epidermal layers. (b) Conceptual illustration of inclined/rotated UV lithography to obtain microneedle arrays. The fabrication

Figure 2 (a) Fabrication process of the microneedle array. (b) Fabricated microneedle arrays. Scale bar:

1 mm. (c) SEM images of a microneedle fabricated at an inclined angle of 15 deg and UV energy density

of 1500 mJ/cm2.

1443

Page 3: 1442 W...Over 0.2 mm of height is required to penetrate epidermal layers. (b) Conceptual illustration of inclined/rotated UV lithography to obtain microneedle arrays. The fabrication

Table 1 Dimensions of microneedls at UV energy density of 1900 mJ/cm2.

J. Control. Release

Biomater.

J. Micromech. Microeng.

1444