Microneedle Template

Manufactured by: Micropoint Technologies Pte Ltd

3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606 [email protected]

Micropoint Technologies Pte Ltd 3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606 Tel: +65 6262 4250 Email: [email protected]

Microneedle Template

Figure A Diagram A

Our disruptive technology MPatchTM Microneedle Templates (Figure A) incorporates cutting-

edge microneedle technology for moulding top-quality dissolvable microneedles. Based on our

proprietary fabrication technology, a stainless steel master mould is machined from which silicone

templates are moulded for making dissolvable microneedle patches. These silicone templates do

not degrade after repeated use. The dissolvable microneedles made from these templates have

sharp tips and well-defined edges.

Diagram A shows the parts of a silicone template. A: microneedle height; B: microneedle base;

C: microneedle pitch, which refers to the tip to tip distance; D: patch size; E: gap, it can be

calculated using following formula: E = microneedle pitch – microneedle base; F: length of last

microneedle cavity to the edge of patch, it can be calculated using following formula:

F = (patch size – [(n - 1) x pitch]) / 2, where n = number of microneedles in one array.

MPatchTM Microneedle Templates are

exclusively made for producing dissolvable

microneedle patches with excellent quality

and repeatability. These templates are made

of silicone rubber which is heat and chemical

resistant, and extremely durable.

Instructions for Use Ensure that the

MPatchTM Microneedle Templates are clean

by washing with mild soap and letting them

air dry completely. Next, pipette a small

quantity (50µl – 100µl) of the drug mixture

onto the microneedle catchment. Subject the

templates to centrifugal force for >60

seconds to ensure that all microneedle

cavities are completely filled-up. Then, dry

the patches (30% - 45% RH) for 4 – 48 hours

depending on the material used. Lastly, use

an adhesive tape to vertically de-mould the

formed microneedle patch from the

templates.

Product Specifications Characteristic Specification

Dimensions 19mm (Dia) x 4mm (H)

Material RTV Silicone (PDMS)

Array Size 6x6, 10x10, 15x15, etc.

Sterilization Autoclave (Optional)

Microneedle Dimensions

< 1,000µm Height (A) 100 – 250µm Base (B); 500 – 1500µm Pitch (C); 8x8/10x10mm2 Patch (D)

No. of Use Repeated Use

Operating Temp. -25 – 200 OC

F

D

B

C

E

A


3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606.


Mini Applicator

Our disruptive technology MPatchTM Mini Applicator incorporates cutting-edge microneedle technology

for effectively applying microneedle patches on the skin (5mm – 15mm in diameter). This includes

stainless steel, plastic and dissolvable microneedle patches. Our applicators are engineered to provide the

required speed and force so that the micronneedles can penetrate the skin at 100% penetration rate.

MPatchTM Mini Applicator is used to apply

microneedle patches on the skin effectively

for drug delivery or cosmetic purposes.

Special Features MPatchM Mini Applicator

is specially engineered to apply microneedle

patches effectively by ensuring 100%

penetration rate. The penetration speed and

force is optimized to provide repeatable and

reproducible results.

Instructions for Use Affix a microneedle

patch on to the sample seat and cock the

applicator. Place the transparent cap over a

targeted skin site and apply mild pressure to

tension the skin. Activate the applicator by

pressing the trigger button. Hold the device

in place for at least 10 seconds or longer to

ensure that the microneedles are completely

inserted into the skin. This holding time is

crucial for the microneedle to dissolve in the

skin (if the microneedles are dissolvable).

Product Specifications

Characteristic Specification

Dimensions 20mm Dia. X 70mm L

Application Speed ~2.0 m/s

Impact Strength: Normal/ Enhanced/ High

Application Force ~1.6 N (Normal Strength)

Operations Mode Spring operated

Maximum Patch 15mm Dia.

No. of Use Repeated Use (Personal)


3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606.


Casing and

Casing Insert

Our MPatchTM casing and MPatchTM casing insert are specially designed for the installation of

microneedle patches onto the MPatchTM Mini Applicator. They are also designed to provide protection

to the microneedle and aid in the installation of microneedle patches onto the applicator.

MPatchTM casing and MPatchTM casing

insert are used to install microneedle patches

onto the applicator without causing damage

to the microneedle patch.

Special Features MPatchTM casing and

MPatchTM casing insert are specially

designed to aid in the installation of

microneedle patch onto the MPatchTM Mini

Applicator. They are also designed to

provide protection and storage to

microneedle patch and reduce the risk of

damaging microneedle patch during

installation.

Instructions for Use Remove the liner of

medical grade adhesive on the casing insert.

Affix a microneedle patch on the casing

insert with medical grade adhesive. Store

casing insert with microneedle patch in a

casing. Cock the applicator with casing

loaded with microneedle patch. The

applicator is now ready for microneedle

application on targeted skin.

Product Specifications

Casing


Material PC+ABS

Dimensions 16mm Dia. X 32mm H



Casing Insert


Material PC+ABS

Dimensions 16mm Dia. X 30mm H



DATA SHEET LIQUID DISPENSING

9-POINT LIQUID DISPENSING HUB (METAL)

A 3x3 stainless steel hollow microneedle hub

Features:

Made from stainless steel needles

Tips are strong enough for repeated

skin penetrations

Sufficiently Sharp tips (<1 um)

Contains a luer-slip female for

connecting to a typical syringe

Potential Applications:

Industrial multiple-point dispensing:

o Glues, sealants, reagents etc.

Instructions for Use:

Load liquid to be dispensed in a

syringe barrel.

Connect the loaded syringe to the 9-

Point Liquid Dispensing Hub via the

luer-ship female connector.

Dispense liquid by pushing the

plunger.

Discard the used device into a

sharps collector.

3x3 Stainless Steel Hollow Microneedle Hub (Close-Up)

Physical Specifications

No Parameter Unit Value

1 Needle Height um 1,000 – 4,000

2 Needle Tip Size um < 1.0

3 Needle O.D. um 250

4 Inner Diameter um 150

5 Needle Pitch um 3,500

6 Needle Array Size - 5 or 9 (3x3)

Manufactured by Micropoint Technologies Pte Ltd 3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606. Email Address: [email protected]

No. Part No. Product Code Part Name Material Patch SizeArray Size

Needle Height

Needle Base

Needle Pitch

Price US$/10pcs

1 ST-01 ST-10x10-H300B100P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 300 100 500 $525.002 ST-02 ST-10x10-H400B150P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 400 150 500 $525.003 ST-03 ST-10x10-H500B150P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 500 150 500 $525.004 ST-04 ST-10x10-H500B200P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 500 200 500 $525.005 ST-05 ST-10x10-H600B200P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 600 200 500 $525.006 ST-06 ST-15x15-H600B200P500 Silicone Template PDMS 8 mm x 8 mm 15 x 15 600 200 500 $525.007 ST-07 ST-10x10-H700B200P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 700 200 500 $630.008 ST-08 ST-10x10-H800B200P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 800 200 500 $630.009 ST-09 ST-6x6-H800B250P500 Silicone Template PDMS 10 mm x 10 mm 6 x 6 800 250 500 $630.00

10 ST-10 ST-6x6-H1000B250P1000 Silicone Template PDMS 10 mm x 10 mm 6 x 6 1000 250 1000 $787.5011 ST-11 ST-6x6-H1000B250P1500 Silicone Template PDMS 10 mm x 10 mm 6 x 6 1000 250 1500 $787.5012 ST-12 ST-15x15-H500B200P1500 Silicone Template PDMS 30 mm x 30 mm 15 x 15 500 200 1500 $420.00/4pcs13 ST-13 ST-25x90-H300B200P500 Silicone Template PDMS 34 mm x 67 mm 25 x 90 300 200 500 $630/4pcs14 ST-14 ST-60x60-H250B100P850 Silicone Template PDMS 70 mm x 70 mm 60 x 60 250 100 850 $600/2pcs

No. Part No. Product Code Part Name MaterialPatch Size

Array Size

Needle Height

Needle Base

Needle Pitch

Price US$/pc

1 DMNA-01 DMNA-10x10-H300B100P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 300 100 500 $52.502 DMNA-02 DMNA-10x10-H400B150P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 400 150 500 $52.503 DMNA-03 DMNA-10x10-H500B150P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 500 150 500 $52.504 DMNA-04 DMNA-10x10-H500B200P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 500 200 500 $52.505 DMNA-05 DMNA-10x10-H600B200P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 600 200 500 $52.506 DMNA-06 DMNA-15x15-H600B200P500 Dissolving Microneedles HA 8 mm x 8 mm 15 x 15 600 200 500 $52.507 DMNA-07 DMNA-10x10-H700B200P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 700 200 500 $63.008 DMNA-08 DMNA-10x10-H800B200P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 800 200 500 $78.759 DMNA-09 DMNA-6x6-H800B250P500 Dissolving Microneedles HA 10 mm x 10 mm 6 x 6 800 250 500 $78.75

10 DMNA-10 DMNA-6x6-H1000B250P1000 Dissolving Microneedles HA 10 mm x 10 mm 6 x 6 1000 250 1000 $78.7511 DMNA-11 DMNA-6x6-H1000B250P1500 Dissolving Microneedles HA 10 mm x 10 mm 6 x 6 1000 250 1500 $78.7512 DMNA-12 DMNA-15x15-H500B200P1500 Dissolving Microneedles HA 30 mm x 30 mm 15 x 15 500 200 1500 $105.0013 DMNA-13 DMNA-25x90-H300B200P500 Dissolving Microneedles HA 34 mm x 67 mm 25 x 90 300 200 500 $157.5014 DMNA-14 DMNA-60x60-H250B100P850 Dissolving Microneedles HA 70 mm x 70 mm 60 x 60 250 100 850 $200

No. Part No. Part Name Material Patch Size Array Size Price US$AC-01 SA-01 Spring Applicator PC + ABS N/A N/A $126.00AC-02 CS-01 Casing PC + ABS 8mm x 8mm 10 x 10 $10.50AC-03 CI-01 Casing Insert PC + ABS 8mm x 8mm 10 x 10 $5.25

Microneedle Template

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