Detection of antibody-mediated reduction of annexin A5 anticoagulant activity in plasmas of patients...

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Transcript of Detection of antibody-mediated reduction of annexin A5 anticoagulant activity in plasmas of patients...

Detection of antibody-mediated reduction of annexin A5 anticoagulant activity in plasmas of patients with the

antiphospholipid syndrome

by Jacob H. Rand, Xiao-Xuan Wu, Robert Lapinski, Waander L. van Heerde, Chris P. Reutelingsperger, Pojen P. Chen, and Thomas L. Ortel

BloodVolume 104(9):2783-2790

November 1, 2004

©2004 by American Society of Hematology

Schematics of annexin A5 binding and resistance assays. .

Jacob H. Rand et al. Blood 2004;104:2783-2790

©2004 by American Society of Hematology

Annexin A5 binding studies.

Jacob H. Rand et al. Blood 2004;104:2783-2790

©2004 by American Society of Hematology

Annexin A5 binding assays for patient plasma groups.

Jacob H. Rand et al. Blood 2004;104:2783-2790

©2004 by American Society of Hematology

Annexin A5 resistance studies.

Jacob H. Rand et al. Blood 2004;104:2783-2790

©2004 by American Society of Hematology

Annexin A5 resistance assays for patient plasma groups.

Jacob H. Rand et al. Blood 2004;104:2783-2790

©2004 by American Society of Hematology

Correlation analysis for annexin A5 resistance and annexin A5 binding assays.

Jacob H. Rand et al. Blood 2004;104:2783-2790

©2004 by American Society of Hematology