AP Biology 2007-2008

Tour of the Cell 1

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Cells: Introduction to cells- great video 2:55

http://www.youtube.com/watch?v=gFuEo2ccTPA

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Prokaryotebacteria cellsProkaryote

bacteria cellsTypes of cells

Eukaryoteanimal cellsEukaryote

animal cells

- no membrane boundorganelles

- Membrane bound organelles

Eukaryoteplant cellsEukaryoteplant cells

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Why organelles? Specialized structures

specialized functions cilia or flagella for locomotion

Containers partition cell into compartments create different local environments

separate pH, or concentration of materials distinct & incompatible functions

lysosome & its digestive enzymes

Membranes as sites for chemical reactions unique combinations of lipids & proteins embedded enzymes & reaction centers

chloroplasts & mitochondria

mitochondria

chloroplast

Golgi

ER

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Cells gotta work to live! What jobs do cells have to do?

make proteins proteins control every

cell function make energy

for daily life for growth

make more cells growth repair renewal

AP Biology 2007-2008

Building Proteins

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Proteins do all the work!

cellscells

DNADNA

proteinsproteins

organismorganismRepeat after me…

Proteins do all the work!

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Cells functions Building proteins

read DNA instructions build proteins process proteins

folding modifying

removing amino acids adding other molecules

e.g, making glycoproteinsfor cell membrane

address & transport proteins

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Building Proteins Organelles involved

nucleus ribosomes endoplasmic reticulum

(ER) Golgi apparatus vesicles

nucleus ribosome ERGolgi

apparatusvesicles

The Protein Assembly Line

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nuclearpores

nuclearpore

nuclear envelopenucleolus

histone protein

chromosome

DNA

Function protects DNA

Structure nuclear envelope

double membrane membrane fused in spots to create pores

allows large macromolecules to pass through

Nucleus

What kind of molecules need to

pass through?

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DNA

NucleusmRNA

nuclearmembrane

smallribosomal

subunit

largeribosomal

subunit

cytoplasm

mRNA

nuclear pore

production of mRNA from DNA in nucleusproduction of mRNA from DNA in nucleus

mRNA travels from nucleus to ribosome in cytoplasm through nuclear pore

mRNA travels from nucleus to ribosome in cytoplasm through nuclear pore

1

2

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Nucleolus Function

ribosome production build ribosome subunits from rRNA & proteins exit through nuclear pores to cytoplasm &

combine to form functional ribosomes

smallsubunit

large subunit

ribosome

rRNA &proteins

nucleolus

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smallsubunit

largesubunitRibosomes

Function protein production

Structure rRNA & protein 2 subunits combine 0.08m

RibosomesRough

ER

SmoothER

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Three-dimensional views of the ribosome, showing rRNA in dark blue (small subunit) and dark red (large subunit).

Lighter colors represent ribosomal proteins.

AP Biology membrane proteins

Types of Ribosomes Free ribosomes

suspended in cytosol synthesize proteins that

function in cytosol

Bound ribosomes attached to endoplasmic

reticulum synthesize proteins

for export or for membranes

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Endoplasmic Reticulum Function

processes proteins manufactures membranes synthesis & hydrolysis of many compounds

Structure membrane connected to nuclear envelope &

extends throughout cell

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Types of ER

rough smooth

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Smooth ER function Membrane production Many metabolic processes

synthesis synthesize lipids

oils, phospholipids, steroids & sex hormones

hydrolysis hydrolyze glycogen into glucose

in liver

detoxify drugs & poisons in liver ex. alcohol & barbiturates

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Membrane Factory Build new

membrane synthesize

phospholipids builds membranes

ER membrane expands bud off & transfer

to other parts of cell that need membranes

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Rough ER function Produce proteins for export out of cell

protein secreting cells packaged into transport vesicles for export

Which cellshave lot of rough ER?

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Synthesizing proteins

cytoplasm

cisternalspace

mRNA

ribosome

membrane ofendoplasmic reticulum

polypeptide

signalsequence

ribosome

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Golgi Apparatus

Which cellshave lots of Golgi?

transport vesicles

secretoryvesicles

Function finishes, sorts, tags & ships cell products

like “UPS shipping department” ships products in vesicles

membrane sacs “UPS trucks”

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Golgi Apparatus

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Vesicle transport

vesiclebuddingfrom roughER

fusionof vesiclewith Golgiapparatus

migratingtransportvesicle

protein

ribosome

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Endomembrane system animation http://www.goldiesroom.org/

Shockwave_Pages/011--Golgi%20Complex.htm

Regents Biology

DNA

RNA

ribosomes

endoplasmicreticulum

vesicle

Golgi apparatus

vesicle

proteinon its way!

protein finishedprotein

Making Proteins

TO:

TO:

TO:

TO:

nucleus

AP Biology

proteins

transportvesicle

Golgiapparatus

vesicle

smooth ER

rough ER

nuclear porenucleus

ribosome

cellmembrane protein secreted

cytoplasm

Making proteinsPutting it together…

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http://www.nytimes.com/2009/10/06/science/06cell.html lysosome article- 2 pages

Summarize and reflect

Organelles 3D- structures to music onlyhttp://www.youtube.com/watch?v=f1dp7tSC3Wg

Cellular world

Cells- introduction/review- 4minhttp://www.youtube.com/watch?v=u54bRpbSOgs

AP Biology 2007-2008

Any Questions!!