DETERMINANTS DETERMINANTS OF VENTRICULAR FUNCTION DETERMINANTS DETERMINANTS OF VENTRICULAR FUNCTION STROKE VOLUME PRELOAD CONTRACTILITY CARDIAC OUTPUT.
Cellular Receptors Chapter 2. Binding of Drugs in/to Cells Receptor = Drug “target” –Membrane protein –Enzyme –Nucleic acid Most drugs bind receptors.
Imaging Drugs in the Brain ENAS 880 / NSCI 523 Fall 2010 Morris/Cosgrove [email protected] kelly [email protected] .
INTRODUCTION Depression afflicts approximately 5% of the population, 1-2% with bipolar disorder. Suicide from depression is 25-30% of depressed population.
Drug Tolerance A shift in the dose-response curve to the right Cross Tolerance Exposure to one drug can produce tolerance to other similar acting drugs.