20172017FHS Research Plenary 2017

http://fhs.mcmaster.ca/grad/research_plenary.html

Tuesday, May 16 - Thursday, May 18Awards Reception: Wednesday, May 31

HEALTH SCIENCES

Celebrating Excellence in the areas of graduate student and postdoctoral fellow health science research

Poster Sessions

Oral Sessions

Awards Reception

Jan and Mien Heersink Reading Pavilion (Health Sciences Library, 1st floor)

Jan and Mien Heersink Reading Pavilion (Health Sciences Library, 1st floor)

Michael G. DeGroote Centre for Learning and Discovery (Rooms MDCL 3020, 3022, 3023, 3024)

FHS Research Plenary 2017

Schedule

May 1610:00am - 12:00pm

May 1710:00am - 12:00pm and 1:30pm-3:30pm

May 1810:00am - 12:00pm

May 161:30pm - 3:30pm

May 314:00 - 6:30pm Awards Reception - Wine & Cheese

May 181:30pm - 3:30pm

Health Sciences Graduate Programs and Postdoctoral Studies

3

Tuesday, May 16th, 10:00am-12:00pm

Amanda Baskwill Health Research Methodology

PhD Just Don’t Be Creepy: Male Massage Therapists’ Experiences of Barriers and Strategies for a Successful Practice

Lindsay Broadfield Medical Sciences PhD Improving radiation response in hormone resistant prostate cancer with combined Metformin and Salicylate treatment

Jennifer Cozier Rehabilitation Science

PhD Associations Between Arterial Stiffness And Hemodynamic Response To Orthostatic Challenge In Individuals With Chronic Stroke

Thilini Dilungahawatta

Medical Sciences MSc Antibiotic Driven Changes on Gut Motility Suggest Direct Modulation of Enteric Nervous System (ENS)

Joanna Dionne CIP (Health Research Methodology)

PhD Diarrhea During Critical Illness: results from the DICE pilot study

Sara El Zahed Biochemistry PhD Chemical-Chemical Combinations Under Nutrient Limitation Identify Unique Intracellular Interactions

Wael Elhenawy Biochemistry & Biomedical Sciences

PDF Understanding the Adaptation of Crohn’s Disease-Associated Escherichia Coli to the Host Environment

Alex Green Medical Sciences PhD Elevated Serotonin (5-HT) impairs brown adipose tissue (BAT) and 5-HT receptor blockade improves whole body metabolism

Poster Presentations

FHS Research Plenary

4

Herman Johal CIP (Health Research Methodology)

PhD A cost-analysis of treatment strategies for comminuted 3 and 4 part proximal humerus fractures in elderly individuals: A comparison of conservative and operative management approaches

Michelle Kameda CIP (Biochemistry) PhD Investigating the role of the RNA binding protein, Musashi in Group 3 medulloblastoma

Matthew Leyenaar Health Research Methodology

PhD Paramedic Lift Assist Calls - Outcomes and Interventions

Crystal Mahadeo Neuroscience PhD Blocking Alzheimer’s-associated phosphorylation of tau protein does not affect tau-induced BDNF down-regulation in vitro

Nancy Nashid CIP (Medical Sciences)

MSc Predictors of loss to follow-up in HIV-exposed uninfected (HEU) children

Siddharth Nath Biochemistry MD/PhD

Mutations in ataxin-7 and mitochondrial topoisomerase type I lead to ataxia without retinal degeneration

Alexander Oberc Biochemistry MD/PhD

Investigating the role of antibiotics and adherent-invasive E. coli in the pathogenesis of Crohn’s disease

Brendan Patterson Biochemistry MSc The Role of Paternal Obesity in Fetoplacental Development

Madeline Simpson Chemical Engineering

PhD Hydrophobized Microgels for the Delivery of Antipsychotic Drugs to the Brain

Piyanka Sivarajah Biochemistry MSc Developing a tool for proteomic analysis of splicing factors associated with specific mRNA molecules

Health Sciences Graduate Programs and Postdoctoral Studies

5

Allison Sohanlal Health Science Education

MSc Prevalence of “Not Applicable” used in rating clinical skills of child life interns

Laura Teague Nursing PhD Estimated Cost of Hospitalization for Persons with Spinal Cord Injury undergoing Stage IV Pelvic Pressure Ulcer Reconstruction

Caressa Tsai Biochemistry MSc High-throughput screening for innate immune potentiators targeting the enteric pathogen Salmonella Typhimurium

Kara K. Tsang Biochemistry MSc Complete prediction of antimicrobial resistance phenotype from genome sequence by expanded algorithms for prediction of antimicrobial efflux

Umair Majib Health Research Methodology

MSc Prostate Cancer Patient Perspectives on the Use of Information in Treatment Decision-Making: A Systematic Review and Qualitative Meta-Synthesis

Scott Walsh Pathology & Molecular

PDF Uncoupling of immunotherapy-induced tumor regression and on-target, off tumor toxicity via type 1 IFN inhibition

Kimberly Young Medical Sciences MSc Targeting Glutamate in Prostate Cancer-Induced Depression

FHS Research Plenary

6

Wednesday, May 17th, 10:00am-12:00pm

Solen Abdulla Biochemistry MSc Investigating novel β-catenin signaling mechanisms in an embryonic stem cell model

Gésine Alders Neuroscience PhD Emotional Conflict Task Performance in Individuals with Major Depressive Disorder and Healthy Controls

Stephen Boulton Biochemistry PhD Free Energy Landscape Remodeling of the Cardiac Pacemaker Channel Explains the Molecular Basis of Familial Sinus Bradycardia

Allison Brown Health Research Methodology

MSc Is pre-clerkship the PRIME time for learning quality improvement? A mixed-methods study of early applications of quality in medical education to improve medical education quality

Chad Brown Medical Sciences MSc Effect of Slow Synaptic Excitation on Myenteric Intrinsic Primary Afferent Neuron BKCA Channel Activity

Bhargavi Duvvuri Medicine PDF Development of peptide immunotherapy for rheumatoid arthritis: Identification of T cell epitopes from citrullinated autoantigens

Lisa Dyce Neuroscience PhD Examining the Predictive Association of Irritability with BPD versus MDD in Youth

Michelle Heyer Nursing MSc Improving Residents’ Quality-of-Life in Long Term Care through Neighbourhood Team Development

Angela Huynh Medical Sciences MSc Pathogenic Epitopes on Platelet Factor 4 Involved in Heparin-induced Thrombocytopenia

Health Sciences Graduate Programs and Postdoctoral Studies

7

Jennifer Kennedy Rehabilitation Science

PhD A scoping review to explore how universal design for learning is described and implemented by health professionals in school settings

Katherine Kennedy Biochemistry PhD Maternal diet-induced obesity is associated with altered fetal gut development

Ghaidaa Khalifa Rehabilitation Science

PhD Workplace Accommodations for Adults with Autism Spectrum Disorder: A Scoping Review

Michelle Phoenix Rehabilitation Science

PhD Parent Engagement in Child Therapy Services: The Journey to Child Health and Happiness

Shreya Prashar Neuroscience MSc Role of Neurotrophic Factors in Bipolar Disorder: CDNF and MANF as Biomarkers and Therapeutic Targets

Maleeha Qazi Biochemistry PhD Therapeutic targeting of tumorigenic EphA2+/EphA3+ brain tumor initiating cells with bi-specific antibody in human glioblastoma

Nick Quinn Public Health MSc Provincial inequities of income-related informal caregiving

Shivani Shah Global Health MSc Building a Comprehensive Framework: Optimizing Short-term Volunteer Experiences Abroad

Kanwaldeep Singh Biochemistry PhD Mitochondrial dysfunction results in impaired adipogenesis and insulin sensitivity in obesity

Anastasiya Slyepchenko

Neuroscience MSc Changes in Biological Rhythms and Mood from Pregnancy to Early Postpartum in Women with Mood Disorders: Preliminary Results

Kiho Son Medical Sciences MSc Fluid Shear Stress Modulates Eosinophil Function Including Adhesion, Morphologiscal Changes, and Migration

FHS Research Plenary

8

Melodie Yun-Ju Song

Health Policy PhD How are public health policymakers in Ontario making sense of vaccine misinformation on social media?

John Vrbensky Medical Sciences MSc Do CD8+ T Cells Target Platelets in Immune Thrombocytopenia?

Jennifer Wong eHealth MSc Quality and completeness of reporting of mobile phone interventions for lifestyle change: An assessment of randomized control trials

Julian Yabut Medical Sciences PhD Absence of Mast-Cell Derived Serotonin Synthesis Attenuates Obesity and Metabolic Dysfunction By Potentiation of Brown and Beige Adipose Tissue Function

Juan José Yepes-Nuñez

Health Research Methodology

PhD Developing Summary of Findings Tables in Network Meta-Analysis: A user testing study

Health Sciences Graduate Programs and Postdoctoral Studies

9

Wednesday, May 17th, 1:30pm-3:30pm

Alexandria Afonso Biochemistry PhD Modeling genetic determinants of early-onset coronary artery disease using patient-derived induced pluripotent stem cells

Rashik Ahmed Biochemistry MSc The Molecular Basis of EGCG-induced remodelling of Amyloid Beta from toxic to non-toxic oligomers

Shaymaa Ba Armah Rehabilitation Science

MSc Effects of physical activity interventions on overweight and obese individuals with chronic obstructive pulmonary disease: a systematic review and meta-analysis

Kevin Chathely Medical Sciences MSc High-Density Lipoprotein Mediated Protection of Macrophages against Apoptosis Requires Scavenger Receptor Class B Type 1 Activity and Sphingosine-1 -Phosphate

BJ Cunningham Rehabilitation Science

PhD A population-based study of communicative participation in preschoolers with speech-language delays

Jamie Dawdy Nursing PhD Low-level laser therapy for the prevention of pain, swelling and trismus after surgical removal of impacted mandibular third molars: An update of a systematic review and meta-analysis

Krystin Donais, Sarah Hobbs

Occupational Therapy

MSc Mind.me: Piloting a Technology-Friendly Youth Mental Health Program

Jillian Halliday Health Research Methodology

PhD Teacher Student Relationships and Mental Health Service Utilization in Ontario School Youth

Nikola Ivetic Biochemistry PhD Diagnosis of heparin-induced thrombocytopenia using Calcein-AM

FHS Research Plenary

10

Eric Kwon Medical Sciences MSc Role of gut serotonin in the production of Antimicrobial Peptides

Shawn Lee, Stefanie Pueschel

Occupational Therapy

MSc Literature review and parent education module: 24 hour postural care

Linda Liu Biochemistry MSc Assessing the Functional Asymmetry of the Bacillus subtilis MutL Homodimer

Victoria A. Marko Biochemistry MSc PilWXY1 contribute to type IV pilus-independent virulence of Pseudomonas aeruginosa

Sawayra Owais Neuroscience MSc The impact of a post-delivery sleep protection intervention on postpartum maternal mental health

Manreet Padwal Medical Sciences PhD The role of WNT5A in peritoneal membrane injury

Sophie Poznanski Medical Sciences MSc Harnessing Patients’ Own Expanded NK Cells for Ovarian Cancer Treatment

Rana Qadeer Health Research Methodology

MSc Substance use disorder among emerging and young adults: an epidemiological study

Alexander Qian Medical Sciences MSc High-Density Lipoprotein Protects Macrophanges Against Apoptosis through BH-3-only Bcl-2 family member Bim

Michael Ranieri Biochemistry MSc Biofilm Stimulation in Response to Sub-Inhibitory Levels of Thiostrepton Reveals Unexpected Activity Against Pseudomonas aeruginosa

Christopher Rowley Neuroscience PhD Disrupted Trajectory of Intracortical Myelin in Bipolar Disorder

Health Sciences Graduate Programs and Postdoctoral Studies

11

Ruheena Sangrar Rehabilitation Science

PhD Identifying demographic and behavioural determinants of older drivers’ comfort and confidence behind-the-wheel: Examining driving behaviour with a gender lens

Manpreet Sehmbi Neuroscience PhD Cognitive performance is predicted by intracortical myelin signal intensity in young adults with Bipolar I Disorder

Nigar Sekercioglu Health Research Methodology

PhD A Critical Appraisal of Acute Kidney Injury Clinical Practice Guidelines Using the AGREE II Instrument

Victoria Serkis Medical Sciences MSc IBS-D Microbiota Induces Gut-Brain Dysfunction by Disrupting Intestinal Neural and Immune Pathways

Janine Strehmel Pathology & Molecular Medicine

PDF Identification of novel immune modulators to bolster innate immunity

FHS Research Plenary

12

Thursday, May 18th, 10:00am-12:00pm

Krysta Andrews Neuroscience PhD Assessing Contextual Influences On Child Development: A Work In Progress

Joyce Chan Public Health MSc Community Paramedicine: Key program elements and training

Erick Duan Health Research Methodology

MSc Characteristics and risk stratification of patients with ICU-acquired Clostridium difficile infection: a multicentre retrospective cohort study

Pamela Durepos Nursing PhD Assessing Palliative Care Content in Dementia Care Guidelines: A systematic review

Melissa Elgie Neuroscience MSc Endowment, Ownership and Hoarding Behaviours in Youth with Obsessive-Compulsive Disorder (Work in progress)

Victor Gordon Biochemistry PhD Identifying novel mechanisms of Wnt regulation through HCS

Aaron Jones Health Research Methodology

PhD The Impact of Home Care Visits on Same Day ED Utilization in Ontario

Ielaf Khalil Public Health MSc When you least expect it, this happens... it’s already growing: Problematizing the definition of unmet need for family planning

Sara Makaremi Biomedical Engineering

PhD Raster Image Correlation Spectroscopy for Measuring Diffusion of Receptors on Macrophage Membrane

Melissa McCradden Neuroscience PhD The psychiatric sequelae of youth concussion: Patterns of clinical presentation

Madeline McDonald Global Health MSc Palliative Care in Jordan for Syrian Refugees

Health Sciences Graduate Programs and Postdoctoral Studies

13

Aidan Giangregorio Rehabilitation Science

PhD The Short Performance Physical Battery Predicts Emergency Department visits and Hospitalization in Geriatric Outpatients

Emilia Paron Chemical Engineering

PhD Brush Polymer Analogues of PLA-PEG as a Platoform for Nanoparticle Based Drug Delivery

Amanda Pereira Physiotherapy MSc Assessing a Tri-Stage Interprofessional Learning Experience on Aging

Celeste Petrusevski Rehabilitation Science

PhD A Public Health Role for Physiotherapy: Promoting physical literacy for adults with chronic conditions

Yasir Rehman Health Research Methodology

PhD Qualitative analysis of the patient’s pre-operative expectation and information given by surgeons to patients undergoing lumbar decompressive surgery

Omar Shawaf Neuroscience MSc Investigating the Role of MANF in the Pathophysiology of Parkinson’s Disease

David Speicher Pathology & Molecular Medicine

PDF Detection of Viral Antibodies via Dried Oral Swabs

Danielle Vitali Medical Sciences MSc The effect of curcumin on HSV-2 infection and inflammation in the murine genital mucosa

Amy Wright Nursing PhD Data Collection Methods in Qualitative Health Research with Indigenous Peoples: Can We Do Better?

Michael Zoratti Health Research Methodology

PhD Home care clients with a stroke diagnosis in Ontario have increased limitations with communication and ADLs

FHS Research Plenary

14

Irtaza Tahir, Omer Gulzar, Eva Luu, Ahmed Hussain, Nirav Naik

eHealth MSc Health Literacy In Immigrant Populations

Gabriela Rozanski, Julie Gourlay, Kelsey Jack

Physiotherapy MSc Validating the Clinical Frailty Scale and Exploring Pre-Frailty in Community-Dwelling Older Adults with Pre-Clinical Disability

Amie Matthews, Brittany Nolan, Emma Saaltink

Occupational Therapy

MSc “Do-Live-Well” concept in an in-patient mood disorder clinic: Advancing an occupational perspective to health promotion

Alana Boyczuk, James Deloyer, Kyle Ferrigan, Kevin Muncaster

Physiotherapy MSc Professional values and behaviours: What do Canadian physiotherapists think?

Health Sciences Graduate Programs and Postdoctoral Studies

15

Oral Presentations

MDCL 3020 Tuesday, May 16th, 1:30-3:30pm

Monica De Paoli Chemical Biology MSc Investigating the molecular mechanisms by which sex hormones modulate beta cell health

Emily Day Medical Sciences PhD Canagliflozin reduces inflammation and increases energy expenditure in a mouse model of atherosclerosis

Nishanth Merwin Biochemistry MSc Developing tools to accelerate natural product discovery and characterization

Sabrina Syan Neuroscience PhD Resting-state functional connectivity following Acute Tryptophan Depletion in Perimenopause Women on Estrogen Therapy: Preliminary Results

Natashia Singh Biomedical Engineering

MSc Fractal Dimension of Resting EEG is a Prospective Biomarker for Treatment Response to Electroconvulsive Therapy

Susie Son Biochemistry MSc High mobility group box 1 is a ROS-dependent regulator of huntingtin localization

Arman Shekari Neuroscience MSc Assessing Retrograde Axonal Transport of Neurotrophins in Alzheimer’s Disease

FHS Research Plenary

16

MDCL 3022

Jenna Smith-Turchyn Rehabilitation Science

PhD Bridging the Gap: Incorporating Exercise Evidence into Clinical Practice in Breast Cancer Care in Ontario-A Pilot Trial Protocol

Shaminder Dhillon Rehabilitation Science

PhD Promoting an Understanding of Disability Research Relationships through an Arts-Based Educational Activity

Sherald Sanchez Global Health MSc Impact of Canada’s Resettlement Programs on the Integration of Syrian Refugee Women in Canadian Society: a Descriptive Study

Kim Madden Health Research Methodology

PhD Predicting Loss to Follow-up Risk in Trauma Patients in Randomized Controlled Trials: An Example from the FLOW Trial

Ahmad Firas Khalid Health Policy PhD Enhancing health system resilience: Strengthening the use of research knowledge in policy and practice during the Syrian Refugee crisis

Theresa Aves Health Research Methodology

MSc The effects of antiretroviral drug resistance testing on mortality in people living with HIV: a systematic review and meta-analysis

Health Sciences Graduate Programs and Postdoctoral Studies

17

MDCL 3023

Janaki Iyer Pathology & Molecular Medicine

PDF Quantitative Evaluation of Bleeding Due to Platelet Function Disorders Associated with Dense Granule Deficiency and/or Impaired Aggregation Responses

Jennifer Reid Biochemistry PhD Using hESCs with enhanced hematopoietic progenitor output and trisomy 12 to investigate primary B-cell CLL

David Donker Pathology & Molecular Medicine

PDF Selection and characterization of a DNA aptamer inhibiting coagulation factor Xia

Sarah Daisy Kosa Health Research Methodology

PhD Hemodialysis Infection Prevention Protocols Ontario—Shower Technique (HIPPO-ST): A Pilot Randomized Trial

Linda Nguyen Rehabilitation Science

MSc Effects of Botulinum Toxin Treatment in Non-ambulatory Children and Adolescents with Cerebral Palsy: Understanding Parents’ Perspectives

Naomi Fink Pediatrics PDF Association of pre-pregnancy BMI and current adiposity with blood glucose and lipid profiles during early pregnancy

Reed Siemieniuk Health Research Methodology

PhD WikiRecs and BMJ RapidRecs: rapid and trustworthy recommendations and evidence summaries

FHS Research Plenary

18

MDCL 3024

John Krzeczkowski Neuroscience PhD Neurodevelopment in 3 year-olds Following Prenatal Exposure to Maternal Gestational Diabetes

Cynthia Monaco Medical Sciences PhD Diabetic Myopthy: Impact of Type 1 Diabetes on Skeletal Muscle Mitochondrial Bioenergetics in Humans

Reema Shah CIP (Public Health) MSc Thyroid Dysfunction and Cardiovascular Events in Patients with Dysglycemia: an ORIGIN substudy

Tamika Jarvis Public Health MSc Defining Public Health Systems: A critical interpretive synthesis of how public health systems are defined and classified

Hanyan Zou Medical Sciences MSc Power Doppler scores in feet predict function outcomes in early Rheumatoid Arthritis

Isabel Rodrigues Rehabilitation Science

MSc Development and validation of a new tool to measure the facilitators and barriers to exercise in people with osteopenia and osteoporosis

Health Sciences Graduate Programs and Postdoctoral Studies

19

MDCL 3020 Thursday, May 18th, 1:30-3:30pm

Lili Aslostovar Biochemistry PhD Dopamine receptor modulation with Thioridazine allows selective targeting of transformed progenitors in human acute myeloid leukemia

Alexandra Mayhew Health Research Methodology

PhD The Dietary Portfolio Intervention and Risk Factors of Metabolic Syndrome

Minesh Kapadia Psychiatry & Behavioural Neurosciences

PDF Systemic Autoimmunity: A Sex-Specific Factor in Alzheimer’s-Like Disease

Wojtek Wiercioch Health Research Methodology

PhD Can we make patient versions of clinical practice guidelines more applicable to patients and the public?

Kristie Poole Neuroscience PhD Trajectories of Social Anxiety in Children at High and Low Risk: Influence of Child Cortisol Reactivity and Parental Social Anxiety

Sarah Neil-Sztramko Nursing PDF If you build it, who will come? A description of current users of the McMaster Optimal Aging Portal

Safaa Naiel Medical Sciences MSc Endoplasmic reticulum stress inhibition blunts the development of essential hypertension in the spontaneously hypertensive rat

FHS Research Plenary

20

MDCL 3022

Puja Bagri Medical Sciences PhD A novel role of IL-17 in mediating efficient anti-viral memory responses in the female genital tract

Bushra Ilyas Biochemistry PhD Regulatory evolution drives immune evasion by Salmonella Typhimurium

Branavan Manoranjan

Biochemistry MD/PhD

Context-specific tumour suppressive function of the canonical Wnt pathway in pediatric medulloblastoma

Nadeem Murtaza Biochemistry PhD Altered TAOK2 activity causes autism-like cognitive and neurological abnormalities through RhoA signaling

Jocelyn Wessels Pathology and Molecular Medicine

PDF Understanding how a Hormonal Contraceptive might Impact Susceptibility to Human Immunodeficiency Virus

Luseadra McKerracher

Biochemistry & Biomedical Sciences

PDF An assessment of knowledge translation to the public about the developmental origins of disease risk: A first look at the Mothers to Babies (M2B) Hamilton Study

Health Sciences Graduate Programs and Postdoctoral Studies

21

MDCL 3023

Lundie Richards Health Management

MSc Using accreditation to drive leadership within the Jamaican health sector

Jahangir Sartaj Global Health MSc Global Burden of Hepatitis C: Integrating Hepatitis C Surveillance, Prevention, and Treatment Services into Existing Global HIV and TB Services

Sergei Muratov Health Research Methodology

PhD Senior High Cost Uers in Ontario - Insight into Incremental Healthcare Use and Costs

Marcela Velez Health Policy PhD Colombian adoption of the UK model of comparative effectiveness research: A case of policy transfer

Holly Tschirhart Nursing MSc Examining the prevalence of diabetes-related distress in women with diabetes in pregnancy

Nazari Dvirnik CIP (Health Research Methodology)

MSc Steroids in Cardiac Surgery: A Systematic Review and Meta-Analysis

Carly Whitmore Nursing MSc Transitioning to Practice in Long-Term Care: From Nursing Student to Nurse Leader

FHS Research Plenary

22

MDCL 3024

David Bakhshinyan Biochemistry PhD Genes preserving stem cell state in Group 3 MB BTICs contribute to therapy evasion and relapse

Elizabeth Perez Guzman

Medical Sciences MSc Germ-free mice colonized with microbiota from an anxious patient exhibit anxiety-like behavior and altered BDNF expression, which are attenuated with infliximab treatment

Shana Aadl Shaya Medical Sciences PhD FXIII and EACA increase thrombus stability and decrease pulmonary embolism in an in vivo mouse model of venous thromboembolism, but EACA increses thrombus size

Rebekah Sherburn Medicine PDF Novel mechanisms of action of Peptide Immunotherapy

Dustin Little Biochemistry & Biomedical Sciences

PDF Mechanistic insights into hierarchal effector secretion in Enteropathogenic Escherichia coli

Joshua McGrath Medical Sciences MSc Investigating the impact of cigarette smoke on dendritic cell-mediated antibody responses in the murine nasal mucosa

Health Sciences Graduate Programs and Postdoctoral Studies

23

20172017FHS Research Plenary 2017

Please Join UsFor the fi nal day of the 2017 FHS Research PlenaryHosted by Dr. Catherine HaywardAssociate Dean of Graduate Studies (Health Sciences)

4:00-6:30pm Awards ReceptionWine & Cheese

Awards Reception - Wednesday, May 31, 2017Jan and Mien Heersink Reading Pavilion (Health Sciences Library, 1st fl oor)