What are Stem Cells? Classification of Stem Cells Current Uses
of Stem Cells Legal Restrictions Induced Pluripotent Stem Cells
Therapeutic Cloning Potential Use of Stem Cells New & Exciting
Research Conclusion Table of Contents
Slide 4
Stem cells are pluripotent. Stem cells serve as a repair system
for the body. Stem cells have the potential in many different areas
of health and medical research. By studying stem cells we can
understand diseases and how serious conditions occur. Stem cells
may be used one day in the future to make cells and tissues for
therapy for many different diseases. Stem Cells
Slide 5
Classification Formed as a normal part of embryonic development
Can be isolated from an early embryo and grown in a dish
Slide 6
Also called adult stem cells Exist naturally in body Important
for growth, healing, and replacing cells lost through daily wear
and tear Can become only a subset of related cell types
Classification
Slide 7
Stem cell therapies are not new Somatic Cell Therapy for blood
and skin diseases Stem cell therapies are not new Somatic Cell
Therapy for blood and skin diseases Current Uses Regenerative
capabilities of human skin to treat victims of severe burns using
skin transplants Possible cause stem cells located under top layer
of skin that reproduce worn out skin cells daily After severe
burns, source of these reproducing stem cells are destroyed Past:
used to treat burns by transplanting sections of skin of undamaged
area to burned areas but if not enough unharmed skin found then no
treatment Now: scientists grow sheets of new skin by culturing stem
cells from small pieces of healthy skin
Slide 8
Current Uses Can already treat leukemia, sickle cell anemia,
bone marrow damage, some metabolic disorders and immunodeficiencies
where the body has lost ability to replenish its healthy blood
cells Hematopoietic stem cell gives rise to all blood cells Only
way to use hematopoietic stem cells is bone marrow transplants
Scientists are exploring new use for these stem cells that go
beyond blood related diseases
Slide 9
Canada: Governed by Assisted Humans Reproduction Act Protect
principles of free and informed consent, human dignity, non-
commercialization of gametes and embryos and respect for embryos
Not ethically acceptable to create human embryos for research In
vitro fertilization embryos may be used Reproductive and research
cloning are prohibited and punishable Legalities
Slide 10
Slide 11
Classification Created artificially by reprogramming patients
cells Made from readily available somatic cells An alternate to hES
but not the same
Slide 12
Classification Method of cloning patient-specific embryonic
stem cells Also known as nuclear transfer
Slide 13
Potential Uses There are many potential uses and applications
of Stem Cells. The three I am going to discuss are: Resource for
Testing New Medical Treatments Development and Disease Research
Regenerative Medicine
Slide 14
Potential Uses
Slide 15
Antipsychotic drug, Thioridazine, found by McMaster University
researchers, is a smart drug that kills only cancer stem cells and
appears to have no effect on normal cells Was removed from shelved
by Health Canada because it causes irregular heartbeat that may
cause sudden death One of 26 drugs found by Bhatia and his team
Studying how Thioridazine works also led McMaster researchers to
discover new ways in which cancer stem cells grow and evolve. New
Research
Slide 16
As we grow from fertilized eggs into fully formed human beings,
stem cells give rise to all of our differentiated tissues and
organs. Stem cells continue to play an important role throughout
our lives as they help to heal and maintain our bodies. Stem cells
offer an exciting promise for future therapies and may be used one
day to make cells and tissues for therapy for many devastating
diseases like Parkinson's, Alzheimer's and Diabetes.
Conclusion
Slide 17
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Genetic Science Learning Center (1969, December 31) Stem Cells In
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http://learn.genetics.utah.edu/content/tech/stemcells/scfuture/
Slide 18
References UBC. (2004, August). Stem Cell Bioengineering.
Retrieved May, 2012, from http://www.scq.ubc.ca/
stem-cell-bioengineering/ National Institute of Health Research.
(2009). Stem Cell Basics. Retrieved May 2, 2012, from
http://stemcells.nih.gov/info/basics/basics6.asp The National
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The National Academies. (2009). Stem Cell Basics - Ethics.
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bls/stemcells/ethics.shtml The National Academies. (2009). Stem
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http://dels-old.nas.edu/
bls/stemcells/working-with-stem-cells.shtml Stem Cell Network.
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730705--drug-that-kills- cancer-stem-cells-has-safety-concerns