continued from inside back cover

Inhibition of infl ammatory mediators contributes to the anti-infl ammatory activity of KYKZL-1 via MAPK and NF- B pathway

Guang-Lin Xu , Yi-Fang Du , Jing Cheng , Lin Huan , Shi-Cui Chen , Shao-Hua Wei , Zhu-Nan Gong , Jie Cai , Ting Qiu , Hao Wu , Ting Sun , Gui-Zhen Ao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221

The role of renal proximal tubule P450 enzymes in chloroform-induced nephrotoxicity: Utility of renal specifi c P450 reductase knockout mouse models

Senyan Liu , Yunyi Yao , Shijun Lu , Kenneth Aldous , Xinxin Ding , Changlin Mei , Jun Gu . . . . . . . . . . 230 Evaluation of the pharmacokinetics and cardiotoxicity of doxorubicin in rat receiving nilotinib

Zhi-yong Zhou , Li-li Wan , Quan-jun Yang , Yong-long Han , Yan Li , Qi Yu , Cheng Guo , Xiao Li . . . . 238 Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes

Kimberly R. Doherty , Robert L. Wappel , Dominique R. Talbert , Patricia B. Trusk , Diarmuid M. Moran , James W. Kramer , Arthur M. Brown , Scott A. Shell , Sarah Bacus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245

Treating chronic arsenic toxicity with high selenium lentil diets Shweta Sah , Albert Vandenberg , Judit Smits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256