BioForumGenomics: Insights and Impacts
SpeakersDr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSFDr. Jonathan Eisen – Genome Center, UCDDr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF
HostDr. Brian Simison – California Academy of Sciences
BioForum – Genomics
9:00-9:30 Welcome and Introduction - Brian Simison 9:30-10:20 Dr. Jeff Boore - Genomics: Where have we come and where are
we going? 10:20-10:40 Break 10:40-11:30 Dr. Katherine Pollard - What makes us Human? 11:30-12:20 Dr. Jonathan Eisen - Evolution of microbes and their genomes: a
phylogenomic perspective 12:20-1:20 Lunch
1:20-2:10 Dr. Nadav Ahituv - Future Genomics
2:10-3:00 Panel Question & Answer Session
2
1975 – developed chain termination method for DNA sequencing.
– Sequenced first complete genome (bacterial phage)
1955 – determined amino acid sequence of Insulin
2 Nobel awards!!
Cycle Sequencing - Fred Sanger
4
Center for Comparative Genomics
Standard DNA sequencing
Population genetic studies
Whole genome shotgun sequencing
ABI 3130xl - 16-capillary sequencer
Amersham Megabace 4500 - 384-capillary sequencer
PhyloCluster 136-core Apple Xserve High Performance Computing Cluster
Interactive web interface
Computer Lab 4 powerful desktops (two 8-core Macs & two 4-core PCs)
Center for Comparative Genomics
CryoCollection cDNA libraries, Genomic DNA, BAC libraries, etc
2-d barcoded -80º collection
Dynamically linked to tissue and specimen collections
Center for Comparative Genomics
Center for Comparative Genomics
Jack Dumbacher – Evolution of Bird Viruses
David Mindell – mitochondrial genomics & phylogenomics of bird viruses
Brian Simison – evolution and origin of Mitochondrial genomes (mechanisms of gene order change).
Genomics research
Role of Genomics at California Academy of Sciences?
The field of genomics is not only informing us about ourselves, but it is helping to better understand the living world around us so we can make informed decisions on how to protect that living world
Dr Jeff Boore
• B.S. - Penn State
• Ph.D. - University of Michigan
• NIH Postdoctoral Fellow – University of Minnesota
• Visiting Researcher – University of Michigan
• Head of Evolutionary Genomics at JGI
• Adjunct Professor – UC Berkeley
• Owner and CEO – Genome Project Solutions
Dr.Jeff Boore
1980 to 2000 – served in US Navy & Air National Guard as a Naval Officer
Attended Navy Flight School
Lt. Colonel Jeff Boore
Dr. Lt. Colonel Jeff Boore
Genomics: Where have we come and where are we going?
BioForumGenomics: Insights and Impacts
SpeakersDr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSFDr. Jonathan Eisen – Genome Center, UCDDr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF
ModeratorDr. Brian Simison – California Academy of Sciences
Dr Katie Pollard
• B.A. – Pomona College, CA - Anthropology & Mathematics
• Watson Fellow – socio-political aspects of SIDS in New Zealand, Indonesia & Australia
• Ph.D. – UC Berkeley – Biostatistics
• Postdoctoral Fellow – UC Berkeley
• Postdoctoral Fellow – UC Santa Cruz – Chimpanzee Genome project
• Professor – UC Davis Genome Center & Dept. of Statistics
• Professor & Investigator – UC Gladstone Institute & Div. of Biostatistics, UCSF
Dr Katie Pollard
What makes us Human?
BioForumGenomics: Insights and Impacts
SpeakersDr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSFDr. Jonathan Eisen – Genome Center, UCDDr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF
ModeratorDr. Brian Simison – California Academy of Sciences
Dr Jonathan Eisen
• B.S. – Harvard
• Ph.D. – Stanford – Evolution of DNA repair processes
• Faculty – The Institute for Genomic Research (TIGR)
• Professor – UC Davis Genome Center & Dept. of Medical Microbiology & Immunology, School of Medicine
• Adjunct appt – Joint Genome Institute
• Editor in Chief – PLoS Biology – an open access journal “… making the world’s scientific and medical literature a freely available public resource”
• Phylogenomics and the Origin of Novelty in microorganisms
Dr Jonathan Eisen
Evolution of microbes and their genomes: A phylogenomic perspective
BioForumGenomics: Insights and Impacts
SpeakersDr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSFDr. Jonathan Eisen – Genome Center, UCDDr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF
ModeratorDr. Brian Simison – California Academy of Sciences
Dr Nadav Ahituv
• B.S. – Tel-Aviv University – General Biology
• Ph.D. – Tel-Aviv University - Human Genetics
• Postdoctoral Fellow – Lawrence Berkeley National Labs - Genomics
• Professor – UC San Francisco - Bioengineering and Therapeutic Sciences, Institute for Human Genetics & Department
of Biopharmaceutical Sciences –
determining the pharmacogenetics of membrane transport proteins that play a role in drug response pathways
Dr Nadav Ahituv
Future Genomics
BioForumGenomics: Insights and Impacts
SpeakersDr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSFDr. Jonathan Eisen – Genome Center, UCDDr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF
ModeratorDr. Brian Simison – California Academy of Sciences
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