Baer - Skeoch/Shane Update

BioForumGenomics: Insights and Impacts

SpeakersDr. Jeff Boore - Genome Project Solutions Dr. Katherine Pollard - Gladstone Institute, UCSFDr. Jonathan Eisen – Genome Center, UCDDr. Nadav Ahituv - Bioengineering and Therapeutic Sciences, UCSF

HostDr. Brian Simison – California Academy of Sciences

BioForum – Genomics

9:00-9:30 Welcome and Introduction - Brian Simison 9:30-10:20 Dr. Jeff Boore - Genomics: Where have we come and where are

we going? 10:20-10:40 Break 10:40-11:30 Dr. Katherine Pollard - What makes us Human? 11:30-12:20 Dr. Jonathan Eisen - Evolution of microbes and their genomes: a

phylogenomic perspective 12:20-1:20 Lunch

1:20-2:10 Dr. Nadav Ahituv - Future Genomics

2:10-3:00 Panel Question & Answer Session

2

1975 – developed chain termination method for DNA sequencing.

– Sequenced first complete genome (bacterial phage)

1955 – determined amino acid sequence of Insulin

2 Nobel awards!!

Cycle Sequencing - Fred Sanger

4

Center for Comparative Genomics

Standard DNA sequencing

Population genetic studies

Whole genome shotgun sequencing

ABI 3130xl - 16-capillary sequencer

Amersham Megabace 4500 - 384-capillary sequencer

PhyloCluster 136-core Apple Xserve High Performance Computing Cluster

Interactive web interface

Computer Lab 4 powerful desktops (two 8-core Macs & two 4-core PCs)


CryoCollection cDNA libraries, Genomic DNA, BAC libraries, etc

2-d barcoded -80º collection

Dynamically linked to tissue and specimen collections



Jack Dumbacher – Evolution of Bird Viruses

David Mindell – mitochondrial genomics & phylogenomics of bird viruses

Brian Simison – evolution and origin of Mitochondrial genomes (mechanisms of gene order change).

Genomics research

Role of Genomics at California Academy of Sciences?

The field of genomics is not only informing us about ourselves, but it is helping to better understand the living world around us so we can make informed decisions on how to protect that living world

Dr Jeff Boore

• B.S. - Penn State

• Ph.D. - University of Michigan

• NIH Postdoctoral Fellow – University of Minnesota

• Visiting Researcher – University of Michigan

• Head of Evolutionary Genomics at JGI

• Adjunct Professor – UC Berkeley

• Owner and CEO – Genome Project Solutions

Dr.Jeff Boore

1980 to 2000 – served in US Navy & Air National Guard as a Naval Officer

Attended Navy Flight School

Lt. Colonel Jeff Boore

Dr. Lt. Colonel Jeff Boore

Genomics: Where have we come and where are we going?



ModeratorDr. Brian Simison – California Academy of Sciences

Dr Katie Pollard

• B.A. – Pomona College, CA - Anthropology & Mathematics

• Watson Fellow – socio-political aspects of SIDS in New Zealand, Indonesia & Australia

• Ph.D. – UC Berkeley – Biostatistics

• Postdoctoral Fellow – UC Berkeley

• Postdoctoral Fellow – UC Santa Cruz – Chimpanzee Genome project

• Professor – UC Davis Genome Center & Dept. of Statistics

• Professor & Investigator – UC Gladstone Institute & Div. of Biostatistics, UCSF

Dr Katie Pollard

What makes us Human?

Dr Jonathan Eisen

• B.S. – Harvard

• Ph.D. – Stanford – Evolution of DNA repair processes

• Faculty – The Institute for Genomic Research (TIGR)

• Professor – UC Davis Genome Center & Dept. of Medical Microbiology & Immunology, School of Medicine

• Adjunct appt – Joint Genome Institute

• Editor in Chief – PLoS Biology – an open access journal “… making the world’s scientific and medical literature a freely available public resource”

• Phylogenomics and the Origin of Novelty in microorganisms

Dr Jonathan Eisen

Evolution of microbes and their genomes: A phylogenomic perspective

Dr Nadav Ahituv

• B.S. – Tel-Aviv University – General Biology

• Ph.D. – Tel-Aviv University - Human Genetics

• Postdoctoral Fellow – Lawrence Berkeley National Labs - Genomics

• Professor – UC San Francisco - Bioengineering and Therapeutic Sciences, Institute for Human Genetics & Department

of Biopharmaceutical Sciences –

determining the pharmacogenetics of membrane transport proteins that play a role in drug response pathways

Dr Nadav Ahituv

Future Genomics

Baer - Skeoch/Shane Update

Documents

Transcript of Baer - Skeoch/Shane Update