AT

P l

evel

(rel

ativ

e lu

min

esce

nce

un

its)

0

25K

50K

75K

100K

Rotenone (nM)0 3 10 30

***

RotRot+DHB

0

10K

20K

30K

Malonate (mM)

0 10 30 100

AT

P l

evel

(rel

ativ

e lu

min

esce

nce

un

its)

MalMal+DHB

A B

C D

G93AG93A+DBH

0 5 10 15 200

10K

20K

30K

40K

50KA

TP

syn

thes

is(r

elat

ive

lum

ines

cen

ce u

nit

s)

(Min)

Tg G93A+DHB

Tg G93A

0

50

100

150

**

AT

P s

yn

the

sis

ra

te(R

LU

/100

s/m

g p

rote

in) 200