4T1Day 0 Day 2 Day 4 Day 6 Day 8

Supplemental 1: Tumor growth imaged with Rluc bioluminescence correlates with volumetric measurements from caliper readings

AB

0

100

200

300

400

0

100

200

300

400

0 2 4 6 8

Tum

or V

olum

e (m

m3)

Time (Days)

Bio

lum

Inte

nsity

(Rlu

c)

Tumor Volume (Rluc)

Tumor Volume (Caliper) 1660

460