1 GL-1543a
EDIT-long-road
The Long Road to a New Medicine
John H. (Wick) Johnson, Ph.D.Pfizer Global Research & Development
Ann Arbor, Michigan
2 GL-1543a
EDIT-long-road
The Long Road to a New Medicine
Discovery
Exploratory Development
Full Development
Registration
3 GL-1543a
EDIT-long-road
The Long Road to a New Medicine
Discovery
Exploratory Development
Registration
Full Development
Project Teamand Plans
Synthesisof Compounds
Screening
EarlySafety
Studies
Candidate
3 GL-1543a
Rev. 11/00
4 GL-1543a
EDIT-long-road
The Long Road to a New Medicine
Large Amounts ofCandidate Medicine
Synthesized
Project Teamand Plans
Synthesisof Compounds
EarlySafety
Studies
CandidateFormulations
Developed
ExtensiveSafety
StudiesStudies in HealthyVolunteers Phase I
Discovery
Exploratory Development
Full Development
Registration
Screening
5 GL-1543a
EDIT-long-road
The Long Road to a New Medicine
Discovery
Exploratory Development
Full Development
Registration
Large Amounts ofCandidate Medicine
Synthesized
Project Teamand Plans
Synthesisof Compounds
EarlySafety
Studies
CandidateFormulations
Developed
ExtensiveSafety
Studies
Screening
Studies in HealthyVolunteers Phase I
Candidate Medicine Tested in3-10,000 Patients (Phase III)
Studies in 100-300Patients (Phase II)
Clinical DataAnalysis
5GL-1543a
Rev. 11/00
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