Autoimmunity 2021 – New dates

28 May – 1 June 2021** Please note that the program is not final.

Friday 28-05-2021080

09:00 - 11:00

WHERE DO WE STAND WITH AUTOIMMUNITY? MC3

  Moderation: D. Bogdanos, University of Thessaly, Rheumatology And Clinical Immunology, Larissa, Greece

 09:00 - 09:30

WHY WE DEVELOP AUTOIMMUNE DISEASES

  Y. Shoenfeld, Sheba Medical Center, Tel Aviv, Israel 09:30 - 10:00

NOVEL ASPECTS OF AUTOIMMUNITY

  C. Perricone, Università degli Studi di Perugia, 06129, Italy 10:00 - 10:30

SLE- NOWADAYS

  G.C. Tsokos, Harvard Medical School, BROOKLINE, United States of America 10:30 - 11:00

DISCUSSION

  

09011:00 - 11:30

COFFEE BREAK MC3

10011:30 - 13:00

AUTOIMMUNE ASPECT OF THE BRAIN MC3

 Moderation: H. Amital1, M. Tektonidou2, 1 , Israel, 2Medical School, National and Kapodistrrian University of Athens, First Department Of Propaedeutic Internal Medicine, Athens, Greece

 11:30 - 12:00

SMALL FIBER NEUROPATHY AND AUTOIMMUNITY

  T. Drori, Sheba medical center, Ramat Gan, Israel 

12:00 - 12:30

NOVEL THERAPIES IN AUTOIMMUNE CNS DISEASES

  E. Shavit Stein, Sheba Medical Center, Ramat Gan, Israel 12:30 - 13:00

VIRUSES, THE BRAIN, THE COMPUTER AND AUTOIMMUNE DISEASE

  Y. Dvir, Microsoft, Tel Aviv, Israel 

10513:00 - 14:00

LUNCH BREAK MC3

11014:00 - 16:00

NEW PHATOGENETIC AND THERAPEUTIC AVENUES IN AUTOIMMUNITY

MC3

 Moderation: O. Shovman1, C. Perricone2, 1Sheba Tel-Hashomer, Zabludowicz Center For Autoimmune Diseases, Tel-Hashomer, Israel, 2Università degli Studi di Perugia, Rheumatology, Department Of Medicine, 06129, Italy

 14:00 - 14:30

MOLECULAR MIMICRY AND AUTOIMMUNITY

  D. Bogdanos, University of Thessaly, Larissa, Greece 14:30 - 15:00

BIOSIMILAR IN AUTOIMMUNITY

  H. Amital, Sheba Medical Center, Tel-Hashomer, Israel 15:00 - 15:30

CURRENT STRATEGIES ON ANTIPHOSPHOLIPID SYNDROME MANAGEMENT

  M. Tektonidou, Medical School, National and Kapodistrrian University of Athens, Athens, Greece

 15:30 - 16:00

AUTOIMMUNE DYSAUTOMIA (NEW AUTOANTIBODIES)

  V. Ryabkova, Saint Petersburg State University, Saint Petersburg, Russian Federation 

Saturday 29-05-2021145

08:30 - 10:30

THE AUTOIMMUNITY IN THE MUSCLE AND IN PREGNANCY– UPDATE

MC3

  Moderation: T. Drori1, H. Amital2, 1Sheba medical center, Neyrology, Ramat Gan, Israel, 2 , Israel

 08:30 - 09:00

PREGNANCY IN AUTOIMMUNE RHEUMATIC DISEASES

  A. Tincani, , Italy 09:00 - 09:30

LARGE COHORT OF PREGNANT APS PATIENTS

  V. Bitsadze, , Russian Federation 09:30 - 10:00

AUTOIMMUNE MYOPATHIES

  O. Shovman, Sheba Medical Center, Tel-Hashomer, Israel 10:00 - 10:30

ALLERGEN IN AUTOIMMUNITY

  A.S. Tanay, Ramat Gan, Israel 

15010:30 - 11:00

COFFEE BREAK MC3

15511:00 - 13:00

ACADEMY OF AUTOIMMUNITY MC3

 11:00 - 11:30

CHECKPOINT INHIBITORS INDUCED HPA ACCESS AUTOIMMUNE ENDOCRINOPATHY

  R. Percik, Sheba Medical Center , Ramat Gan, Israel 11:30 - 12:00

MECHANICAL STRESS AS A TRIGGER FOR AUTOIMMUNE DISEASE?

  G. Wick, , Austria 12:00 - 12:30

AUTOANTIBODIES AND CARDIAC ARRHYTHMIAS

  V. Ryabkova, Saint Petersburg State University, Saint Petersburg, Russian Federation 12:30 - 13:00

T2T IN SLE: WHERE DO  WE STAND? 

  C. Vasconcelos, UMIB-ICBAS-UPorto, Porto, Portugal 

14015:30 - 17:30

INDUSTRY SUPPORTED SESSION NIKOS SKALKOTAS

 15:30 - 15:30

WORKSHOP IS ORGANIZED AND SUPPORTED BY Thermo Fisher

  

17018:00 - 19:45

OPENING CEREMONY FOLLOWED BY WELCOME RECEPTION

ALEXANDRA TRIANTI

 

Sunday 30-05-2021180

08:00 - 10:00

PL01 PLENARY SESSION ALEXANDRA TRIANTI

  Moderation: H. Moutsopoulos1, Y. Shoenfeld2, G. Hughes3, 1 , Greece, 2Sheba Medical Center, Zabludowicz Center For Autoimmune Diseases, Tel Aviv, Israel, 3 , United Kingdom

 08:00 - 08:30

SPONDYLOARTHRITIS SPECTRUM OF DISORDERS: AUTOIMMUNE, AUTOINFLAMMATORY OR A BIT OF BOTH?

  D. Mcgonagle1, A. Watad2, 1Leeds University, Leeds, United Kingdom, 2Sheba Medical Center, Tel-Hashomer, Israel

 08:30 - 09:00

POLYAUTOIMMUNITY; WHAT IS IT AND WHY IS IT IMPORTANT?

  J.M. Anaya, , Colombia 09:00 - 09:30

B CELL DEPLETION THERAPY IN AUTOIMMUNE DISEASES WITH KIDNEY INVOLVEMENT

 D. Roccatello, SCU Nephrology and Dialysis & Center of Research of Immunopathology and Rare Diseases - Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, Turin, Italy

 09:30 - 10:00

DEFINITION OF PHENOTYPES OF PRIMARY SJÖGREN’S SYNDROME. A STEP FORWARD TO PRECISION MEDICINE.

  A. Tzioufas, NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS, ATHENS, Greece

 880

09:00 - 16:00

THE RAZZAQUE-ANAYA PATIENTS FORUM FOR AUTOIMMUNITY

CONFERENCE ROOM 1

  Moderation: M. Tektonidou, Medical School, National and Kapodistrrian University of Athens, First Department Of Propaedeutic Internal Medicine, Athens, Greece

 09:00 - 09:04

WELCOME WORDS FROM THE PRESIDENT OF THE CONGRESS

  Y. Shoenfeld, Sheba Medical Center, Tel Aviv, Israel 09:04 - 09:07

OPENING WORDS FROM THE INBAR PATIENT’S ORGANIZATION

  R. Blass, , Israel

 09:07 - 09:10

OPENING WORDS

  R. Krakow, , United States of America 09:10 - 09:15

INTRODUCTION: PATIENTS' EXPERIENCES AND PERSPECTIVES IN SYSTEMIC AUTOIMMUNE DISEASES

  M. Tektonidou, Medical School, National and Kapodistrrian University of Athens, Athens, Greece

 09:15 - 09:45

PATIENT-CENTERED APPROACH OF THE CENTERS OF EXCELLENCE FOR AUTOIMMUNE DISEASES: CURRENT STATUS AND FUTURE DEVELOPMENT

  A. Tzioufas, NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS, ATHENS, Greece

 09:45 - 10:15

STRESS AND AUTOIMMUNITY

  F. Skopouli, none, Athens, Greece 10:15 - 10:30

OPEN DISCUSSION

  10:30 - 11:00

Coffee break

  11:00 - 11:30

IMPROVING PATIENT-PHYSICIAN COMMUNICATION AND COMPLIANCE TO TREATMENT IN SLE

  D. Boumpas, , Greece 11:30 - 12:00

NEW PROMISING TREATMENTS IN SYSTEMIC SCLEROSIS

  P. Vlachoyiannopoulos, , Greece 12:00 - 12:30

TREATMENT UPDATE IN SYSTEMIC VASCULITIS

  D. Vassilopoulos, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

 12:30 - OPEN DISCUSSION

12:45

  12:45 - 14:00

Lunch break

  14:00 - 14:30

AUTOIMMUNE RHEUMATIC DISEASES: HOLISTIC MANAGEMENT

  L. Sakkas, University of Thessaly, Larissa, Greece 14:30 - 15:00

LIVING WITH LUPUS DAY-BY-DAY

  S. Liossis, , Greece 15:00 - 15:30

QUALITY OF LIFE IN SLE: FIGHTING FATIGUE

  D. Bogdanos, University of Thessaly, Larissa, Greece 15:30 - 15:45

OPEN DISCUSSION

  15:45 - 16:00

CLOSING REMARKS

  M. Tektonidou, Medical School, National and Kapodistrrian University of Athens, Athens, Greece

 190

10:00 - 10:30

COFFEE BREAK, EXHIBITION, POSTERS EXHIBITION HALL

20010:30 - 12:30

PS01- THE DIVERSITY OF SLE PRESENTATION ALEXANDRA TRIANTI

  Moderation: C. Putterman1, G. Zandman-Goddard2, A. Doria3, 1 , United States of America, 2wolfson, Internal Medicine, holon, Israel, 3 , Italy

 10:30 - 10:40

THE LUPUS EPIDEMIC

  G. Hughes, , United Kingdom 10:40 - 10:55

SINGLE CELL RNA SEQUENCING AND HUMAN LUPUS NEPHRITIS

  C. Putterman, , United States of America 10:55 - 11:10

THE NEW EULAR/ACR CLASSIFICATION CRITERIA FOR SLE - LESSONS AND OPEN QUESTIONS

  M. Aringer, , Germany 11:10 - 11:30

NANOPARTICLES AS NEW TOOL FOR THE MANAGEMENT OF AUTOIMMUNE DISORDERS

  P.L. Meroni, IRCCS Istituto Auxlogico Italiano, Cusano Milannino - Milan, Italy 11:30 - 11:40

ETHNICITY AND SOCIOECONOMIC STATUS. IMPACT ON SLE OUTCOME.

  B. Pons-Estel, Regional Center for Autoimmune and Rheumatic Diseases - GO-CREAR, Rosario, Argentina

 11:40 - 11:50

PCSK9 IS ASSOCIATED WITH DISEASE ACTIVITY AND IMPLICATED IN IMMUNE ACTIVATION IN SYSTEMIC LUPUS ERYTHEMATOSUS.

  A. Liu, M. Rahman, I. Hafström, S. Ajeganova, J. Frostegard, Karolinska Institutet, Stockholm, Sweden

 11:50 - 12:00

EROSIVE ARTHRITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS: APPLICATION OF CLUSTER ANALYSIS

  F. Ceccarelli, F. Natalucci, C. Perricone, E. Ceccarelli, C. Pirone, G. Olivieri, T. Colasanti, C. Alessandri, G. Valesini, F. Conti, Università La Sapienza, Rome, Italy

 12:00 - 12:10

SERUM ATHEROGENICITY IN WOMEN WITH UNTREATED SYSTEMIC LUPUS ERYTHEMATOSUS

 

E. Gerasimova1, T. Popkova2, I. Sobenin3, 1V.A. Nasonova Research Institute of Rheumatology, Moscow, Russian Federation, 2V.A.Nasonova Research Institute of Rheumatology, Moscow, Russian Federation, 3National medical research center of cardiology of the Ministry of healthcare of the Russian Federation, Moscow, Russian Federation

 12:10 - 12:20

HIGH MOBILITY GROUP B1 (HMGB1) AND SOLUBLE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS (SRAGE) IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) PATIENTS: TOWARDS A POTENTIAL TREATMENT STRATEGY?

 A. Abou-Raya1, M. Kamel2, E. Abdelghani3, S. Abou-Raya3, 1Faculty of Medicine, University of Alexandria, 00203, Egypt, 2Medical Research Institute, Alexandria, Egypt, 3Faculty of Medicine, University of Alexandria, Alexandria, Egypt

 

12:20 - 12:30

SINGLE-GENE VARIANTS IN A COHORT OF EARLY-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS FROM NORTH INDIA

 

A. Rawat1, M. Sharma1, A. Gupta1, D. Suri1, V. Pandiarajan1, A. Jindal1, N. Sankhyan1, A. Saini1, S. Volpi2, A. Ravelli3, M. Gattorno2, I. Ceccherini2, S. Singh1, 1Postgraduate Institute of Medical Education and Research, Chandigarh, India, 2IRCCS Istituto G. Gaslini, Genoa, Italy, 3Giannina Gaslini Institute, Genoa, Italy

 210

10:30 - 12:30

PS02- INFECTOME, INTERACTOME, MICROBIOME AND AUTOIMMUNITY

BANQUETING

  Moderation: C. Lunardi1, E.E. Hakalehto2, 1 , Italy, 2University of Helsinki, C/o Finnoflag Oy, Kuopio, Finland

 10:30 - 10:50

INFECTION AND AUTOIMMUNITY

  C. Lunardi, , Italy 10:50 - 11:10

PATIENT EXAMPLES OF IMBALANCED MICROBIOME WITH ANTIBIOTIC, TOXIC OR METABOLIC EMISSIONS

  E.E. Hakalehto, University of Helsinki, Kuopio, Finland 11:10 - 11:30

MOLECULAR MIMICRY AS A TRIGGER OF AUTOIMMUNITY: REKINDLING AN OLD FLAME

  D. Bogdanos, University of Thessaly, Larissa, Greece 11:30 - 11:50

IMPACT OF INFECTIONS IN AUTOIMMUNE RHEUMATIC DISEASES AND PREGNANCY

  L. Jara, Instituto Mexicano del Seguro Social, Mexico City, Mexico 11:50 - 12:00

AGING, LUPUS AND THE MICROBIOME

  N. Katz-Agranov1, G. Zandman-Goddard2, 1 Brookline, United States of America, 2wolfson, holon, Israel

 12:00 - 12:10

HLA ASSOCIATIONS WITH MICROBIOME IN RHEUMATOID ARTHRITIS (RA) PATIENTS AND THEIR FIRST DEGREE RELATIVES (FDR)

 M. Arleevskaya1, E. Boulygina2, E. Shagimardanova2, R. Larionova1, E. Takha2, Y. Renaudineau3, 1Medical School of Kazan, Kazan, Russian Federation, 2University of Kazan, Kazan, Russian Federation, 3Brest University Medical School, Brest, France

 

12:10 - 12:20

SEROPREVALENCE OF PARVOVIRUS B19 AND EPSTEIN-BARR VIRUS IN PREGNANT WOMEN WITH AUTOIMMUNE DISEASES AND IN HEALTHY PREGNANT WOMEN

 S. De Carolis1, C. Garufi2, F. Rizzo3, A. Caneschi3, M. Dell'Aquila3, S. Salvi3, A. Giannini2, A. Lanzone3, 1Fondazione Policlinico Gemelli IRCCS , Rome, Italy, 2"Sapienza" Università di Roma, Rome, Italy, 3Fondazione Policlinico Gemelli IRCCS, Rome, Italy

 220

10:30 - 12:30

PS03 - MECHANISM AND ETIOLOGY OF AUTOIMMUNE DISEASES

NIKOS SKALKOTAS

 

Moderation: M. Lidar1, L. Sakkas2, G. Kitas3, 1Tel Aviv University, Sackler School Of Medicine, Tel Aviv, Israel, 2University of Thessaly, Dept. Of Rheumatology And Clinical Immunology, Larissa, Greece, 3DUDLEY GROUP NHS FOUNDATION TRUST, Research And Development, DUDLEY, United Kingdom

 10:30 - 10:50

MECHANISM AND ETIOLOGY OF AUTOIMMUNE DISEASES

  D. Kanduc, University of Bari, Bari, Italy 10:50 - 11:05

AUTO-REACTIVITY AGAINST OXIDATIVE POST-TRANSLATIONALLY MODIFIED NEOANTIGENS IN AUTOIMMUNE DISEASES

  A. Nissim, Queen Mary University of London, London, United Kingdom 11:05 - 11:20

THE ROLE OF SOLUBLE IL-2R IN THE IL-2/IL-2R PATHWAY: THE PARADOX OF IMMUNITY VERSUS TOLERANCE

  J. Damoiseaux, Maastricht University Medical Center, Maastricht, Netherlands 11:20 - 11:30

IDIOTYPE/ANTI-IDIOTYPE NETWORK AND BIOLOGIC DRUGS-ASSOCIATED IMMUNOGENICITY

  J. Alves, Fernando Fonseca Hospital, Amadora, Portugal 11:30 - 11:40

PRO-INFLAMMATORY EFFECTS OF FERRITIN AND H-FERRITIN ON HUMAN MONOCYTES.

  P. Ruscitti, P. Di Benedetto, N. Panzera, P. Cipriani, R. Giacomelli, University of L'Aquila, L'Aquila, Italy

 11:40 - 11:50

MEASUREMENT OF OXIDATIVE STRESS BIOMARKERS IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: THE ROLE OF MALONDIALDEHYDE

  C.M. Gambino1, G. Candore2, S. Milano3, B. Lo Sasso2, C. Scazzone2, G. Iacolino2, R.V.

Giglio2, A. Iacona2, G. Guggino2, G. Bivona2, M. Ciaccio2, 1University of Palermo , Palermo, Italy, 2University of Palermo, Palermo, Italy, 3Paolo Giaccone University Hospital of Palermo, Palermo, Italy

 11:50 - 12:00

INHIBITION OF IRF5 HYPER-ACTIVATION PROTECTS FROM LUPUS ONSET AND SEVERITY

 

S. Song1, S. De1, V. Neslon1, C. Thompson1, S. Sun1, M. He1, D. Li1, T. Shih1, Y. Al-Abed1, E. Capitle2, C. Aranow1, M. Mackay1, W. Clapp3, B.J. Barnes1, 1Feinstein Institute for Medical Research, Manhasset, United States of America, 2Rutgers New Jersey Medical School, Newark, United States of America, 3University of Florida, Gainesville, United States of America

 12:00 - 12:10

CIRCULATING EXTRACELLULAR VESICLES HAVE HIGHER EXPRESSION OF COSTIMULATORY MOLECULES IN LUPUS NEPHRITIS

 

M. Quaglia1, G. Merlotti2, M. Mazzariol2, G. Cappellano3, A. Chiocchetti2, U. Dianzani2, V. Cantaluppi2, 1 TORINO, Italy, 2Center for Traslational Research on Autoimmune and Allergic Disea se—CAAD, University of Eastern Piedmont, Novara, Italy, 3University of Piemonte Orientale UPO, Novara, Italy

 12:10 - 12:20

HSP70, A NOVEL REGULATORY MOLECULE IN B CELL MEDIATED SUPPRESSION OF AUTOIMMUNE DISEASES

  L. Wang, Y. Fu, Y. Chu, Fudan University, Shanghai, China 12:20 - 12:30

THE ROLE OF PAMPS/DAMPS IN THE INDUCTION OF TRAINED INNATE IMMUNITY IN HEALTH AND AUTOIMMUNE DISEASE

  K. Laskari1, E. Karouzakis1, O. Distler2, M. Neidhart1, 1USZ Zürich, Zürich, Switzerland, 2University Hospital Zurich, Zurich, Switzerland

 230

10:30 - 12:30

PS04 - IL17, TH17 AND OTHER CYTOKINES IN AUTOIMMUNITY MC3

 Moderation: A. Perl1, T. Niewold 2, P. Miossec3, 1SUNY, Medicine, Syracuse, United States of America, 2 , United States of America, 3University of Lyon, Clinical Immunology And Rheumatology, Lyon, France

 10:30 - 10:50

IL-17 PRODUCTION BY TH17 CELLS: KEY CONTRIBUTION OF INTERACTIONS WITH MESENCHYMAL CELLS

  P. Miossec, University of Lyon, Lyon, France 10:50 - 11:10

IL.17 AND SPONDYLOARTHROPATIES: WHAT HAPPENS  WITH THE

INHIBITION OF THIS CYTOKINE?  P. Sarzi-Puttini, , Italy 11:10 - 11:25

TARGETING IL-17 IN AUTOIMMUNE CHRONIC URTICARIA

  E. Toubi, Italian Hospital Israel, Haifa, Israel 11:25 - 11:40

TYPE I INTERFERON AS A TARGET IN LUPUS

  T. Niewold   , , United States of America 11:40 - 11:50

ROLE OF IL-17C IN THE DEVELOPMENT OF PULMONARY VASCULITIS

 E. Boschmann1, S. Dolff1, T. Hinkeldein1, P. Van Paassen2, J.W. Cohen Tervaert3, A. Kribben1, O. Witzke1, B. Wilde1, 1University Hospital Essen, University of Duisburg-Essen, Essen, Germany, 2Maastricht University Medical Center, Maastricht, Netherlands, 3 , Canada

 11:50 - 12:00

TH17 CELLS EXPRESSING CD146 ARE SIGNIFICANTLY INCREASED IN PATIENTS WITH SYSTEMIC SCLEROSIS

  A. Gabsi1, A. Dlala2, R. Marrakshi1, 1Université de Tunis El Manar, Tunis, Tunisia, 2Faculty of Sciences of Tunis (Faculté des Sciences de Tunis), Tunis, Tunisia

 12:00 - 12:10

INTERLEUKIN-17 IN PATIENTS WITH IN DIFFERENT FORMS OF NONISCHEMIC CARDIOMYOPATHIES

  H.-P. Schultheiss, Institute of Cardiac Diagnostics and Therapy , Berlin, Germany 12:10 - 12:20

RELATIONSHIP BETWEEN TNF-Α AND IL-6 LEVELS AND ACTIVITY INDICES IN PATIENTS WITH INFLAMMATORY JOINT DISEASES

  K. Kraev1, M. Geneva-Popova2, S. Popova2, 1UMHAT Kaspela, Plovdiv, Bulgaria, 2Medical University-Plovdiv, Plovdiv, Bulgaria

 12:20 - 12:30

ASSOCIATION BETWEEN INFLAMMATORY BACK PAIN FEATURES, ACUTE AND STRUCTURAL SACROILIITIS ON MRI, AND THE DIAGNOSIS OF SPONDYLOARTHRITIS

 

S. Kivity1, S. Gofrit2, F. Abu Baker3, N. Leibushor4, S. Tavor5, M. Lidar6, I. Eshed7, 1Sheba Medical Center, Tel-Hashomer, Israel, 2 Tel Aviv, Israel, 3Hillel Yaffe Medical Center, affiliated to the Ruth and Rappaport Faculty of Medicine, Hadera, Israel, 4The Zabludowicz Center for Autoimmune Diseases, Ramat Gan, Israel, 5Hebrew university, Jerusalem, Israel, 6Tel Aviv University, Tel Aviv, Israel, 7Sheba Medical Center, Ramat Gan, Israel

 

23510:30 - 12:30

PS05 - CANCER AND AUTOIMMUNITY MC2

  Moderation: M.-C. Maroun, F. Fernandez-Madrid, , 10:30 - 10:50

AUTOIMMUNITY AS THE ENGINE OF BREAST CARCINOGENESIS. A NEW PARADIGM

  F. Fernandez-Madrid, , 10:50 - 11:10

EPIGENETIC MECHANISMS IN BREAST CANCER AND AUTOIMMUNE RHEUMATIC DISEASES

  M.-C. Maroun, , 11:10 - 11:20

MALIGNANCY IN 36 PATIENTS WITH GIANT CELL ARTERITIS AND/OR POLYMYALGIA RHEUMATICA: ANATOMO-CLINICAL CONFRONTATION

 A. Maria1, E. Rubenstein1, V. Rigau1, S. Rivière1, R. Goulabchand1, P. Rullier1, A. Mahr2, P. Guilpain1, 1Montpellier University Hospital, Montpellier, France, 2APHP Saint Louis Hospital, Paris, France

 11:20 - 11:30

NATURAL HUMAN MONOCLONAL IGGS ARE ABLE TO PENETRATE METASTATIC BREAST CANCER CELLS AND PRESENT ANTI-NEOPLASTIC EFFECTS ON CANCER CELL MIGRATION AND VIABILITY

  T. Stivarou, I. Sarrigeorgiou, A. Polychronopoulou, P. Lymberi, Hellenic Pasteur Institute, ATHENS, Greece

 11:30 - 11:40

PROGRESSIVE SYSTEMIC SCLEROSIS IN PATIENT WITH METASTATIC PAROTIS CARCINOMA UNDER CHEMOTHERAPY WITH PACLITAXEL: A CASE FOR THE AUTOIMMUNE BOARD

  R. Ram, N. Sepp, M. Geroldinger-Simic, Ordenklinikum Linz Elisabethinen, Linz, Austria 11:40 - 11:50

VASCULITIS ASSOCIATED WITH MYELODYSPLASTIC SYNDROME AND CHRONIC MYELOMONOCYTIC LEUKEMIA: FRENCH MULTICENTER CASE CONTROL STUDY AND LITERATURE REVIEW.

  A.L. Roupie1, A. Mekinian2, 1saint antine, paris, France, 2Hopital saint-antoine, Paris, France 11:50 - 12:00

A CASE OF PARANEOPLASIC ANCA VASCULITIS

  N. Vieira E Brito, J. Oliveira, J. Ferreira, R. Taborda, A. Figueiredo, P. Alcântara, Centro Hospitalar Lisboa Norte, Lisboa, Portugal

 

12:00 - 12:10

CERVICAL LYMPHADENOPATHY UNCOVERED: KIKUCHI-FUJIMOTO DISEASE AS INITIAL PRESENTATION OF MIXED CONNECTIVE TISSUE DISEASE

  M. Ofilas, J.P. Patricio, Ilocos Training and Regional Medical Center, San Fernando City La Union, Philippines

 12:10 - 12:20

ANTI-DFS70/LEDGFP75 AUTOANTIBODIES AS A POTENTIAL BIOMARKERS IN BREAST CANCER

  M. Ben Azaiz1, J. Ayari1, N. Sakly2, M. Balti1, A. Haddaoui1, E. Gazouani1, 1Military hospital of Tunis, Tunis, Tunisia, 2Fatouma Bourguiba Hospital,Monastir, Tunis, Tunisia

 250

10:30 - 12:30

PS06 - LIVER AND AUTOIMMUNITY KOKKALI

  Moderation: S. Naguwa, , 10:30 - 10:50

INSIGHTS INTO STATE-OF-THE-ART AUTOIMMUNE LIVER DISEASE DIAGNOSTICS

  10:50 - 11:10

ANIMAL MODELS OF AUTOIMMUNE LIVER DISEASE

  Z.-X. Lian, , China 11:10 - 11:20

ANTI-GLYCOPROTEIN 2 AND PR3-ANCA ARE RISK FACTORS OF SEVERE CLINICAL PHENOTYPE, POOR OUTCOME, AND CHOLANGIOCARCINOMA IN PRIMARY SCLEROSING CHOLANGITIS

 

E. Wunsch1, D. Roggenbuck2, G. Norman3, M. Krawczyk4, M. Milkiewicz1, M.A. Aure3, C. Bentow3, M. Mahler3, P. Milkiewicz5, 1Pomeranian Medical University, Szczecin, Poland, 2Medipan GmbH, Dahlewitz / Berlin, Germany, 3Inova Diagnostics, San Diego, United States of America, 4Saarland University Hospital, Homburg / Saar, Germany, 5Medical University of Warsaw, Warsaw, Poland

 11:20 - 11:30

IMMUNE PROFILING AND TARGET IDENTIFICATION IN HUMAN LIVER INFLAMMATORY DISEASES

  K. Alexandropoulos, R. Lyallpuri, L.S. Cemaletin, Icahn School of Medicine at Mount Sinai, New York, United States of America

 11:30 - 11:40

RESCUE OF AUTOIMMUNE HEPATITIS BY SOLUBLE MHC-II MOLECULES IN AN IN VITRO AND IN VIVO MURINE EXPERMENTAL MODEL

  K. Bakela, G. Dimitraki, E. Skoufa, I. Athanassakis, UNIVERSITY OF CRETE, HERAKLION, Greece

 11:40 - 11:50

SERUM MATRIX METALLOPROTEINASE-3 CONCENTRATION IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS

  A. Bauer, Centre of Postgraduate Medical Education, Warszawa, Poland 11:50 - 12:00

GLYCOPROTEIN 2 (GP2) IS PRESENT IN BILE AND MIGHT PLAY A ROLE IN THE PATHOGENESIS OF LITHOGENIC CONDITIONS

 

S. Lopens1, M. Krawczyk2, M. Sowa3, W. Wystrychowski4, R. Król5, R. Staron6, L. Krupa6, K. Gutkowski6, B. Kruk7, M. Grat7, M. Krawczyk7, W. Patkowski7, P. Milkiewicz7, F. Lammert8, K. Zieniewicz7, D. Roggenbuck9, 1Medipan GmbH, Dahlewitz, Germany, 2Saarland University Hospital, Homburg / Saar, Germany, 3Medipan GmbH, Senftenberg, Germany, 4Medical University of Silesia, Katowice, Poland, 5MVZ Medi-Wtal, Wuppertal-Elberfeld, Germany, 6Teaching Hospital, Rzeszów, Poland, 7Medical University of Warsaw, Warsaw, Poland, 8Saarland University Medical Centre, Homburg, Germany, 9Medipan GmbH, Dahlewitz / Berlin, Germany

 12:00 - 12:10

DIAGNOSTIC AND CLINICAL SIGNIFICANCE OF ANTI-KELCH-LIKE 12 AUTOANTIBODIES IN THE PRIMARY BILIARY CHOLANGITIS

  A. Bauer1, A. Habior2, 1Centre of Postgraduate Medical Education, Warszawa, Poland, 2Polish Gastroenterology Foundation, Warsaw, Poland

 12:10 - 12:20

AUTOIMMUNE HEPATITIS: CLINICAL CHARACTERISTICS AND PREDICTORS OF RESPONSE TO TREATMENT OF AUTOIMMUNE HEPATITIS: CLINICAL CHARACTERISTICS AND PREDICTORS OF BIOCHEMICAL RESPONSE TO TREATMENT

  A.A. Tasneem, Sindh Institute of Urology and Transplantation, Karachi, Pakistan 12:20 - 12:30

THE DENDRITIC, ENTEROENDOCRINE AND GLIAL CELLS’S TRIADE IS A PIVOTAL INTESTINAL LUMINAL EVENTS SENSOR AND EFFECTOR: IMPLICATIONS FOR AUTOIMMUNOGENESIS

  A. Lerner1, C. Steigerwald2, T. Matthias1, 1AESKU.GROUP, Wendelsheim, Germany, 2AESKU.Diagnostics, Wendelsheim, Germany

 260

12:30 - 14:00

LUNCH BREAK, EXHIBITION, POSTERS EXHIBITION HALL

27012:45 - 13:45

INDUSTRY SUPPORTED SESSION NIKOS SKALKOTAS

  Moderation: Y. Allanore, , France 12:45 - 12:45

Time to rethink the lung in the context of autoimmune rheumatic diseases

  12:45 - 12:45

WORKSHOP IS ORGANIZED AND SUPPORTED BY Boehringer Ingelheim

  12:45 - 12:50

Welcome and introduction

  Y. Allanore, , France 12:50 - 13:00

SSc-ILD: The archetype of lung involvement in autoimmune rheumatic diseases

  V. Smith, Ghent University, Gent, Belgium 13:00 - 13:10

Non-SSc autoimmune rheumatic diseases: What to look for in the lung and why

  C. Kelly, , United Kingdom 13:10 - 13:20

Unravelling the pathogenesis of lung fibrosis in autoimmune rheumatic diseases

  M. Cutolo, Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genoa, Italy

 13:20 - 13:30

New paradigms in the management of autoimmune rheumatic disease-related ILDs

  Y. Allanore, , France 13:30 - 13:45

Panel discussion

  Y. Allanore, , France 

28014:00 - 16:00

PS07 - THYROID AUTOIMMUNITY ALEXANDRA TRIANTI

 

Moderation: A. Antonelli1, L. Churilov2, I. Lazurova3, 1University of Pisa, Department Of Clinical And Experimental Medicine, Pisa, Italy, 2Saint Petersburg State University, Pathology, Saint Petersburg, Russian Federation, 3Medical Faculty University Košice, Department Of Internal Medicine, Košice, Slovak Republic

 14:00 - 14:20

THYROID AUTOIMMUNE DISORDERS AND SYSTEMIC AUTOIMMUNE DISEASE: A LARGE LONGITUDINAL STUDY

  A. Antonelli, University of Pisa, Pisa, Italy 14:20 - 14:40

THYROID GLAND, BRAIN AND AUTOIMMUNITY

  L. Churilov, Laboratory of the Mosaic of Autoimmunity, Saint-Petersburg, Russian Federation

 14:40 - 14:50

AUTOIMMUNE THYROID DISORDERS ASSOCIATED WITH RHEUMATOLOGIC, OR DERMATOLOGIC, AUTOIMMUNE DISEASES

  P. Fallahi, G. Elia, F. Ragusa, I. Ruffilli, C. Giusti, S.R. Paparo, D. Gonnella, S.M. Ferrari, A. Antonelli, University of Pisa, Pisa, Italy

 14:50 - 15:00

EVALUATION OF INTRAVENOUS TOCILIZUMAB FOR THE THERAPY OF MODERATE TO SEVERE GRAVES' OPHTHALMOPATHY

 

J. Carbone1, M. Di Natale1, M.A. Mejia Gonzalez1, J. Riba2, I. Nieva3, B. Moreno2, 1Hospital general Universitario Gregorio Marañon, Madrid, Spain, 2Hospital General Universitario Gregorio Marañón, Madrid, Spain, 3Hospital General Universitario Gregorio Marañon, Madrid, Spain

 15:00 - 15:10

TREATING THYROID AUTOIMMUNITY WITH LOW DOSE NALTREXONE AND LIFESTYLE CHANGES GUIDELINES FOR TREATING OUR PATIENTS ON MONDAY MORNING

  D. Williamson, Integrative Family Medicine, franklin, United States of America 15:10 - 15:20

A POTENTIAL RISK OF FALSE POSITIVE RESULTS WHEN UTILIZING PURIFIED HUMAN THYROID PEROXIDASE AS ANTIGEN IN ANTI-THYROID PEROXIDASE ANTIBODY TESTS

  C.-C. Lin, C. Konrad, H. Berthold, Thermo Fisher Scientific, Freiburg, Germany 15:20 - 15:30

NEW THERAPIES FOR THE TREATMENT OF THYROID AUTOIMMUNE DISEASES

  S.M. Ferrari, P. Fallahi, G. Elia, F. Ragusa, S.R. Paparo, C. Giusti, D. Gonnella, I. Ruffilli, A. Antonelli, University of Pisa, Pisa, Italy

 15:30 - 15:40

IMPLICATION OF RANTES IN THE DEVELOPMENT OF AUTOIMMUNE THYROIDITIS VIA CHEMOKINE PRODUCTION DOWN-REGULATION BY HHV-6

  L. Sokolovska1, A. Sultanova2, M. Cistjakovs1, E. Cunskis1, M. Murovska1, 1Riga Stradins University, Riga, Latvia, 2RSU, Riga, Latvia

 15:40 - 15:50

PREVALENCE OF LATENT AND OVERT POLYAUTOIMMUNITY IN AUTOIMMUNE THYROID DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS

 A. Botello1, M. Herran1, V. Salcedo1, Y. Rodríguez1, J.-M. Anaya1, M. Rojas2, 1School of Medicine and Health Sciences, Bogotá D.C, Colombia, 2Universidad del Rosario, Bogotá D.C, Colombia

 15:50 - 16:00

PREDICTING THE COURSE OF GRAVES´ ORBITOPATHY AND GRAVES DISEASE BY ANTI-TSH-RECEPTOR AUTOANTIBODY MEASUREMENTS- BINDING ASSAYS VERSUS FUNCTIONAL BIOASSAY

 

S. Lytton1, M. Stöhr2, M. Oeverhaus2, P. Banga3, M. Horstmann4, U. Berchner-Pfannschmidt2, A. Eckstein2, 1SeraDiaLogistics, Munich, Germany, 2University Duisburg Essen, Essen, Germany, 3Kings College, London, United Kingdom, 4Uniklinik Essen, Essen, Germany

 290

14:00 - 16:00

PS08 -CHECKPOINT INHIBITORS AND AUTOIMMUNITY BANQUETING

 Moderation: R. Percik1, D. Bogdanos2, 1Sheba Medical Center , The Institute Of Endocrinology, Ramat Gan, Israel, 2University of Thessaly, Rheumatology And Clinical Immunology, Larissa, Greece

 14:00 - 14:20

CHECK POINT INHIBITORS INDUCED AUTOIMMUNITY

  M. Ehrenfeld, , Israel 14:20 - 14:40

SLE AND IMMUNE CHECKPOINT INHIBITORS

  G. Zandman-Goddard, wolfson, holon, Israel 14:40 - 15:00

ISOLATED AUTOIMMUNE ADRENOCORTICOTROPHIC HORMONE DEFICIENCY: FROM A RARE DISEASE TO THE DOMINANT CAUSE OF ADRENAL INSUFFICIENCY RELATED TO IMMUNE CHECK POINT INHIBITORS

 

R. Percik1, G. Shlomai2, A. Tirosh3, A. Tirosh3, R. Leibowitz Amit4, Y. Eshet3, G. Greenberg2, A. Merlinsky2, E. Barhod2, Y. Steinberg-Silman2, T. Sella5, 1Sheba Medical Center , Ramat Gan, Israel, 2Sheba Medical Center, Ramat Gan, Israel, 3Tel-Aviv University, Tel Aviv, Israel, 4The Chaim Sheba Medical Center, Ramat Gan, Israel, 5Dana-Farber Cancer Institute, Boston, United States of America

 15:00 - 15:10

ANTI PD-L1 TREATMENT SKEWS PAROTID SALIVARY GLAND EPITHELIAL CELL COMPOSITION.

  S. Pringle, B. Van Der Vegt, X. Wang, N. Van Bakelen, A. Vissink, F. Kroese, H. Bootsma, University Medical Center Groningen, Groningen, Netherlands

 15:10 - 15:20

PD-1 EXPRESSION ON CD8+CD28- REGULATORY T CELLS: ASSOCIATION WITH RHEUMATOID ARTHRITIS RELAPSE

 

F. Ajam1, A. Memarian2, M. Aghaei2, S. Mohammadi2, M. Saeedi2, S. Abdolmaleki3, H. Samiei4, N. Behnampour2, 1Golestan University of Medical Sciences, 49189-36316, Iran, 2Golestan University of Medical Sciences, Gorgan, Iran, 3Mazandaran University of Medical Sciences, Sari, Iran, 4Semnan University of Medical Sciences, Semnan, Iran

 15:20 - 15:30

PD(L)-1 INHIBITORS DO NOT ONLY EXACERBATE, BUT ALSO CAUSE DE NOVO PSORIASIS

  V. Reynaert, J. Gutermuth, M. Grosber, UZ Brussel, Jette, Belgium 15:30 - 15:40

MYOSITIS ASSOCIATED WITH IMMUNE CHECKPOINT INHIBITORS: DISPROPORTIONALITY ANALYSES USING THE WORLD HEALTH ORGANIZATION’S ADVERSE DRUG REACTIONS DATABASE.

 

T. Nguyen1, A. Maria1, C. Ladhari1, P. Palassin1, X. Quantin2, C. Lesage1, G. Taïeb1, X. Ayrignac3, P. Rullier1, D. Hillaire-Buys1, O. Lambotte4, P. Guilpain1, J.-L. Faillie1, 1Montpellier University Hospital, Montpellier, France, 2Institute of Cancer Montpellier, Montpellier, France, 3Montpellier Univesity Hospital, Montpellier, France, 4APHP, Kremlin Bicêtre Hospital, Paris, France

 15:40 - 15:50

NEUROLOGIC ADVERSE EVENTS OF IMMUNE CHECKPOINT INHIBITORS AND ANTIBODIES AGAINST NEURAL ANTIGENS.

 

E. Martínez-Hernández1, R. Ruiz-García2, M. Sanchez3, J. Gonzalez3, C. Díaz-Pedroche3, X. Queralt4, J. Gállego5, R. Velasco6, A. Saiz1, J. Dalmau1, F. Graus1, 1Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), BARCELONA, Spain, 2Hospital Clinic, BARCELONA, Spain, 3Hospital 12 de Octubre, Madrid, Spain, 4Laboratori Clínic Territorial de Girona, Girona, Spain, 5Clínica Universitaria de Navarra, Pamplona, Spain, 6Hospital de Bellvitge, Barcelona, Spain

 15:50 - 16:00

ANTICANCER IMMUNOTHERAPY AND RELATED ENDOCRINE ADVERSE EVENTS

  G. Elia, S.M. Ferrari, F. Ragusa, S.R. Paparo, I. Ruffilli, C. Giusti, D. Gonnella, P. Fallahi, A. Antonelli, University of Pisa, Pisa, Italy

 

30014:00 - 16:00

PS09 - NOVEL AUTOANTIBODIES \ RECEPTORS \ AUTOIMMUNE DYSAUTONOMIA

NIKOS SKALKOTAS

 Moderation: H. Heidecke1, V. Somers2, C. Dias3, 1 , Germany, 2Hasselt University, Biomedical Research Institute, And Transnationale Universiteit Limburg, School Of Life Sciences, Diepenbeek, Belgium, 3 , Portugal

 14:00 - 14:20

REGULATORY ANTI-GPCR ANTIBODIES IN THE PATHOGENESIS OF AUTOIMMUNE AND NON-AUTOIMMUNE DISEASES

  G. Riemekasten, , Germany 14:20 - 14:40

Natural activating ß2 adrenergic receptor antibodies and their dysfunction in ME/CFS

  C. Scheibenbogen, Charité, Berlin, Germany 14:40 - 14:55

NOVEL AUTOANTIBODIES IN EARLY AXIAL SPONDYLOARTHRITIS AS A NOVEL TOOL FOR DIAGNOSIS OF A SUBSET OF AXSPA PATIENTS

  V. Somers, Hasselt University, Diepenbeek, Belgium 14:55 - 15:10

RESCUING ORPHAN AUTOANTIBODIES

  M. Fritzler, University of Calgary, Calgary, Canada 15:10 - 15:20

AUTOANTIBODIES TO AUTONOMIC NERVOUS SYSTEM IN NEW AUTOIMMUNE CONDITIONS

  G. Halpert, Sheba Medical Center, Ramat Gan, Israel 15:20 - 15:30

PATHOGENICITY OF FUNCTIONAL AUTOANTIBODIES AGAINST AT1R IN A MOUSE MODEL OF SYSTEMIC SCLEROSIS

  J. Yin1, X. Wang1, X. Yue1, X. Yu1, F. Petersen1, G. Riemekasten2, 1Research Center Borstel, Borstel, Germany, 2 , Germany

 15:30 - 15:40

ROLE OF ANTIBODIES AGAINST CD74 IN SPONDYLOARTHRITIS

 T. Matthias1, G. Sogkas2, L. Kuske2, K. Klose2, K. Kniesch2, L. Jobczyk2, T. Witte2, 1AESKU.GROUP, Wendelsheim, Germany, 2Hannover Medical University, Hannover, Germany

 15:40 - 15:50

PROFILING THE AUTOANTIBODY REPERTOIRE IN VASCULITIS

 

S. Bayati1, Y. Van Sleen2, F. Mescia3, M. Beenes4, E. Toonen4, P. Heeringa2, E. Brouwer2, P. Lyons3, R. Kain5, P. Nilsson1, E. Pin6, 1KTH - Scilifelab, Stockholm, Sweden, 2Department of Rheumatology and Clinical Immunology, Groningen, Netherlands, 3Department of Medicine, Cambridge, United Kingdom, 4R&D Department, Uden, Netherlands, 5Department of Pathology, Vienna, Austria, 6KTH - Scilifelab, Solna, Sweden

 15:50 - 16:00

OPEN ADAMTS13 CONFORMATION, INDUCED BY AUTOANTIBODIES, IS A BIOMARKER FOR SUBCLINICAL IMMUNE-MEDIATED THROMBOTIC THROMBOCYTOPENIC PURPURA

 

E. Roose1, A.-S. Schelpe1, E. Tellier2, G. Sinkovits3, B. Joly4, C. Dekimpe1, G. Kaplanski2, M. Le Besnerais5, I. Mancini6, T. Falter7, C. Von Auer7, H. Feys8, M. Reti9, H. Rossman7, A. Vandenbulcke1, I. Pareyn1, J. Voorberg10, A. Greinacher11, Y. Benhamou12, H. Deckmyn1, R. Fijnheer13, Z. Prohászka3, F. Peyvandi6, B. Lämmle7, P. Coppo14, S. De Meyer1, A. Veyradier4, K. Vanhoorelbeke1, 1KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium, 2Aix-Marseille Univ, Marseille, France, 3Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary, 4Hôpital Saint Louis, AP-HP.Nord, Université de Paris, Paris, France, 5Rouen University Hospital; University of Rouen IFRMP, Rouen, France, 6Università degli Studi di Milano, and Fondazione Luigi Villa, Milan, Italy, 7University Medical Center of the Johannes Gutenberg University, Mainz, Germany, 8Belgian Red Cross-Flanders; Ghent University, Ghent, Belgium, 9Central Hospital of Southern Pest, National Institute of Haematology and Infectious Diseases, Budapest, Hungary, 10Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 11University Medical Center, Greifswald, Germany, 12Rouen University Hospital, Rouen, France, 13University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands, 14Hôpital Saint Antoine, Assistance Publique-Hôpitaux de Paris and Sorbonne Université, Paris, France

 310

14:00 - 16:00

PS10 - JAK INHIBITORS AND AUTOIMMUNITY MC3

  Moderation: H. Amital1, D. Mcgonagle2, M. Aringer3, 1 , Israel, 2 , United Kingdom, 3 , Germany

 14:00 - 14:20

JAK KINASE INHIBITORS -CLINICAL EFFECTS ON INFLAMMATION AND PAIN

  H. Amital, Sheba Medical Center, Tel-Hashomer, Israel 14:20 - 14:40

JAKI: AN INSIGHT INSIDE THE CELL

  C. Perricone, Università degli Studi di Perugia, 06129, Italy 14:40 - 15:00

THE ROLE OF JANUS KINASES IN SLE - TRYING TO UNDERSTANDING

IMPORTANT SIGNALS  M. Aringer, , Germany 15:00 - 15:20

JAK INHIBITORS AND THE EPIGENETIC CONTROL OF THE INTERFERON PATHWAY IN SJÖGREN’S SYNDROME

  A. Charras, P. Arvanity, C. Le Dantec, V. Devauchelle-Pensec, A. Bordron, Y. Renaudineau, Brest University Medical School, Brest, France

 15:20 - 15:30

JAK-INHIBITION WITH BARICTINIB INHIBITS ACTIVATION OF NLRP1/ CASPASE1/GDMSD PYROPTOSIS PATHWAY IN RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLASTS

  W. Xie, L. Wang, L. Ji, Z. Zhang, Peking University First Hospital, Beijing, China 

32514:00 - 16:00

PS11 - AUTOIMMUNITY OF THE SKIN MC2

  Moderation: A. Gilhar1, R. Ahmed2, 1Rappaport Faculty of Medicine, Technion-Israel Institute of Technology,, Skin Research Laboratory, Haifa, Israel, 2 , United States of America

 14:00 - 14:20

SKIN AND AUTOIMMUNITY

  R. Ahmed, , United States of America 14:20 - 14:35

ALOPECIA AREATA : AN AUTOIMMUNE DISEASE OF MULTIPLE PLAYERS 

  A. Gilhar, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology,, Haifa, Israel

 14:35 - 14:50

ROLE OF BIOLOGIC AGENTS IN THE MANAGEMENT OF BEHCET'S DISEASE RELATED UVEITIS

  M. Galeazzi, , Italy 14:50 - 15:00

SEROLOGICAL CHARACTERIZATION OF ANTI-P200 PEMPHIGOID: EPITOPE SPREADING AS A COMMON PHENOMENON

  M.M. Holtsche, S. Goletz, A. Von Georg, N. Van Beek, F. Hübner, D. Zillikens, E. Schmidt, University of Lübeck, Lübeck, Germany

 15:00 - 15:10

PATHOGENIC PROPERTIES OF AUTOANTIBODIES PERSISTING IN THE SERUM FROM PEMPHIGUS’ PATIENTS IN CLINICAL REMISSION AFTER TREATMENT

 

M. Petit1, V. Hébert2, M.-L. Golinski3, M. Barray3, A. Lemieux4, L. Drouot3, M. Maho-Vaillant3, O. Boyer2, S. Calbo3, P. Joly3, 1Université de Rouen Normandie, ROUEN, France, 2Rouen University Hospital, ROUEN, France, 3Normandy University, ROUEN, France, 4Montreal University Hospital Center, Montreal, Canada

 15:10 - 15:20

NEW TESTS FOR DIAGNOSTIC IMPROVEMENT IN AUTOIMMUNE BULLOUS DISEASES

 C. Bonaguri1, A. Russo1, R. Minerba1, A. Picanza1, A. Melegari2, E. De Santis2, T. Trenti2, M. Galante1, R. Perini1, F. Sandei1, 1University Hospital of Parma, Parma, Italy, 2OCSAE Hospital Modena, Modena, Italy

 15:20 - 15:30

CLINICAL, SEROLOGICAL, IMMUNOLOGICAL AND HISTOPATHOLOGICAL CHARACTERIZATION OF PATIENTS WITH FIBROSING FRONTAL ALOPECIA

 

I. Ruiz-Ordoñez1, C. Aragon2, I. Nieto-Aristizábal1, S. Vásquez2, C. Montoya3, A. Sánchez4, L.E. Muñoz4, G.J. Tobón1, 1Fundación Valle del Lili, Universidad Icesi, Cali, Colombia, 2Universidad Icesi, Cali, Colombia, 3Universidad del Norte, Barranquilla, Colombia, 4Fundación Valle del Lili, Cali, Colombia

 15:30 - 15:40

RNASEQ ANALYSIS OF THE IMMUNOLOGICAL DISTURBANCES IN PYODERMA GANGRENOSUM

 

M. Barrera1, E. Santacruz-Sandoval1, W. Lopez-Quintero1, V. Santos2, I. Posso-Osorio1, A. Echeverri1, C. Cañas3, G.J. Tobón1, 1Fundación Valle del Lili, Universidad Icesi, Cali, Colombia, 2Facultad de Medicina, Universidad Icesi, Cali, Colombia, 3Fundación Valle del Lili, Cali, Colombia

 15:40 - 15:50

EFFICACY OF NB-UVB IN PROGRESSIVE VERSUS NON-PROGRESSIVE NON-SEGMENTAL VITILIGO: A COMPARATIVE STUDY SUGGESTING IMMUNOMODULATORY ROLE OF NB-UVB IN VITILIGO.

  B. Khaitan, S. Bhatia, All India Institute of Medical Sciences, New Delhi, New Delhi, India 15:50 - 16:00

DIPEPTIDYL-PEPTIDASE IV INHIBITORS-ASSOCIATED BULLOUS PEMPHIGOID: A CASE-CONTROL STUDY, SYSTEMATIC REVIEW, AND META-ANALYSIS

  K. Kridin, Clalit Healthcare Services, 3081100, Israel 

33014:00 - 16:00

PS12 -DIET, ENVIRONMENT, STRESS AND AUTOIMMUNITY

KOKKALI

  Moderation: I. Gershteyn1, V. Borba2, A. Vojdani3, 1Ajax Biomedical Foundation, Systems Biology, Newton, United States of America, 2Zabludowicz Center for Autoimmune Diseases,

Sheba Medical Center, Tel-Hashomer, Portugal, 3Immunosciences Lab., Inc., Laboratory, Los Angeles, United States of America

 14:00 - 14:15

IMMUNODIETICA: A COMPUTATIONAL APPROACH TO SYSTEMS INTERACTION OF DIET AND AUTOIMMUNE DISEASE

 I. Gershteyn1, A. Burov1, B. Miao2, V. Morais2, L. Ferreira3, 1Ajax Biomedical Foundation, Newton, United States of America, 2University of California San Francisco, San Francisco, United States of America, 3UCSF, San Francisco, United States of America

 14:15 - 14:30

IMMUNODIETICA: TOWARDS AN IMMUNOLOGICAL UNDERSTANDING OF THE ROLE OF DIET IN AUTOIMMUNITY

 L. Ferreira1, A. Burov2, B. Miao3, V. Morais3, I. Gershteyn2, 1UCSF, San Francisco, United States of America, 2Ajax Biomedical Foundation, Newton, United States of America, 3University of California San Francisco, San Francisco, United States of America

 14:30 - 14:50

IMMUNE REACTION BETWEEN FOOD-SPECIFIC ANTIBODIES AND HUMAN TISSUE MAY CONTRIBUTE TO AUTOIMMUNITY.

 A. Vojdani1, L. Gushgari2, E. Vojdani3, 1Immunosciences Lab., Inc., Los Angeles, United States of America, 2Cyrex Laboratories, LLC, Phoenix, United States of America, 3Regenera Medical, Los Angeles, United States of America

 14:50 - 15:00

THE ROLE OF DIET AND LIFESTYLE IN CHRONIC INFLAMMATION

  P. Bastos1, F. Ordoñez2, O. Ruiz2, A. Lucia3, 1 Lisbon, Portugal, 2NutriScience – Education & Consulting, Lisbon, Portugal, 3Universidad Europea de Madrid, Madrid, Spain

 15:00 - 15:10

ASSOCIATION OF EXCESS WEIGHT WITH CLINICAL ACTIVITY AND DIETARY INTAKE DEFICIENCIES IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS

 

M. Meza Meza1, B. Vizmanos-Lamotte2, J.F. Muñoz-Valle2, I. Parra Rojas3, B. Campos-López1, M. Montoya-Buelna2, S. Cerpa Cruz4, E. Oregón Romero2, U. De La Cruz-Mosso1, 1Universidad de Guadalajara, Guadalajara Jalisco, Mexico, 2Universidad de Guadalajara, Guadalajara, Mexico, 3Universidad Autónoma de Guerrero, Chilpancingo, Mexico, 4Hospital Civil de Guadalajara “Fray Antonio Alcalde, Guadalajara, Mexico

 15:10 - 15:20

THE ROLE OF UNMETHYLATED DNA AS A PREDICTIVE BIOMARKER IN NON-IGE MEDIATED FOOD

  B. König1, J. Bellanti2, 1University clinic of Leipzig, Leipzig, Germany, 2Georgetown University Medical Center, Washington, DC, United States of America

 

15:20 - 15:30

CORRELATION OF PLANT LECTINS AND AGGLUTININS IMMUNE REACTIVITY WITH TISSUE ANTIBODIES

  J. Lambert, S. Mejia, Cyrex Laboratories, LLC, Phoenix, United States of America 15:30 - 15:40

AIR POLLUTION: AN INVISIBLE ENEMY OF AUTOIMMUNE DISEASES

  C. Ramírez-Santana1, Y. Acosta-Ampudia1, D. Monsalve1, J.M. Anaya2, 1School of Medicine and Health Sciences, Bogotá D.C, Colombia, 2 , Colombia

 15:40 - 15:50

THE IMPACT OF JET-LAG ON PSORIATIC AND PSORIATIC ARTHRITIS PATIENTS DISEASE SEVERITY SCORES: DOES IT MATTER?

 

M. Adawi1, A. Watad2, N.L. Bragazzi3, H. Amital2, G. Damiani4, 1Padeh and Ziv Hospitals, Azrieli Faculty of Medicine, Bar-Ilan University, Zefat, Israel, 2Sheba Medical Center, Tel-Hashomer, Israel, 3University of Genoa, Genoa, Italy, 4Clinical Dermatology, IRCCS Istituto Ortopedico Galeazzi, Milano, Italy

 15:50 - 16:00

ORGANIC SELENIUM ACCUMULATES AT THE CNS AND DECREASES EAE SEVERITY: A PROMISING THERAPY FOR MULTIPLE SCLEROSIS?

 

S. Zorzella-Pezavento1, J. Toledo1, T. Fraga-Silva1, P. Borim1, L. Oliveira1, E. Oliveira1, L. Périco1, A. Souza1, C. Oliveira2, P. Padilha1, M. Pinatto-Botelho3, A. Santos3, A. Sartori1, 1São Paulo State University (UNESP), Botucatu, Brazil, 2Biorigin Company, Lençois Paulista, Brazil, 3University of São Paulo (USP), São Paulo, Brazil

 340

16:00 - 16:30

COFFEE BREAK, EXHIBITION, POSTERS EXHIBITION HALL

35016:30 - 18:30

PS13 - ANTIPHOSPHOLIPID SYNDROME TOWARDS THE FOURTH DECADE

ALEXANDRA TRIANTI

 

Moderation: A. Makatsariya1, F. Atzeni2, M. Tektonidou3, 1 , Russian Federation, 2Rheumatology Unit, University Of Messina, Messina, Italy, 3Medical School, National and Kapodistrrian University of Athens, First Department Of Propaedeutic Internal Medicine, Athens, Greece

 16:30 - 16:50

PATHOGENESIS OF ANTIPHOSPHOLIPID ANTIBODIES

  T. Atsumi, Hokkaido University, Sapporo, Japan 16:50 - 17:10

MANAGEMENT OF REFRACTORY OBSTETRIC ANTIPHOSPHOLIPID SYNDROME

  R. Cervera, Hospital Clinic Barcelona, Barcelona, Spain

 17:10 - 17:30

PREGNANCY, ANTIPHOSPHOLIPID SYNDROME AND AUTOIMMUNITY

  A. Makatsariya, , Russian Federation 17:30 - 17:40

INDUCTION OF IMMUNOLOGICAL ORAL TOLERANCE IN ANTIPHOSPHOLIPID SYNDROME: AN ANIMAL MODEL

 

A. Shemer1, R. Williams2, E.B. Gonzalezc2, Z. Romay-Penabad2, O. Shovman1, Y. Shoenfeld3, M. Blank1, H. Amital1, 1Sheba Medical Center, Tel-Hashomer, Israel, 2University of Texas Medical Branch, Galveston, United States of America, 3Sheba Medical Center, Tel Aviv, Israel

 17:40 - 17:50

OBSTETRICAL OUTCOME AND TREATMENTS DURING PREGNANCY IN SERONEGATIVE PRIMARY APS: DATA FROM EUROPEAN RETROSPECTIVE STUDY.

  N. Abisror1, A. Mekinian2, 1sain antoine, paris, France, 2Hopital saint-antoine, Paris, France 17:50 - 18:00

PRESENCE OF IMMUNE COMPLEXES OF IGA ABGP1 ANTIBODIES AND B2GP1 ASSOCIATES ELEVATED RISK OF EARLY THROMBOSIS AND MORTALITY AFTER HEART TRASPLANTATION

 M. Serrano1, L. Moran2, J.A. Martinez3, E. Mancebo3, D. Pleguezuelo3, O. Cabrera-Marante3, A. Serrano3, 1Hospital Clinico San Carlos, madrid, Spain, 2Hospital 12 de octubre, madrid, Spain, 3Hospital doce de octubre, madrid, Spain

 18:00 - 18:10

PREECLAMPSIA BEFORE FETAL VIABILITY IN WOMEN WITH PRIMARY ANTIPHOSPHOLIPID SYNDROME- MATERNO-FETAL OUTCOMES IN A SERIES OF 7 CASES

  K. Mayer-Pickel, C. Stern, M. Cervar-Zivkovic, W. Schöll, M. Moertl, Medical University Graz, Graz, Austria

 18:10 - 18:20

IMPACT OF ANTIPHOSPHOLIPID ANTIBODIES ON ASSISTED REPRODUCTION WITH DONOR OOCYTES.

 

B. Algarra Sanchez1, E. Rodriguez De Frias2, M. Fernández Arquero3, A. De La Fuente4, F.J. Gil Etayo2, A. Serrano2, 1Hospital Universitario 12 de Octubre , Madrid, Spain, 2Hospital doce de octubre, madrid, Spain, 3Hospital Clínico San Carlos, Madrid, Spain, 4Instituto Español de Fertilidad, Madrid, Spain

 18:20 - 18:30

CLINICAL EVALUATION AND METHOD COMPARISON OF NOVEL ASSAYS FOR THE DETECTION OF ANTIBODIES ASSOCIATED WITH CELIAC DISEASE

  J. Mangat1, A. Seaman2, E. Wahl1, G. Norman2, O. Springfield2, J. Nibecker2, M.G.

Alessio3, M. Papp4, 1Inova Diagnostics, Inc, San Diego, United States of America, 2Inova Diagnostics, San Diego, United States of America, 3ASST Papa Giovanni XXIII, Bergamo, Italy, 4University of Debrecen, Budapest, Hungary

 360

16:30 - 18:30

PS14 - NEW CYTOKINES AND ANTI-CYTOKINES IN AUTOIMMUNITY

BANQUETING

  Moderation: S. Jacobsen1, F. Nicoletti2, 1 , Denmark, 2University of Catania, Department Of Biomedical And Biotechnological Sciences, Catania, Italy

 16:30 - 16:50

THE MACOPHAGE MIGRATION INHIBITORY FACTOR CYTOKINE SUPERFAMILY IN THE PATHOGENESIS AND TREATMENT OF AUTOIMMUNE DISEASES

  F. Nicoletti, University of Catania, Catania, Italy 16:50 - 17:10

INTERFERON SIGNATURES IN SLE – DIVERSITY AND PHENOTYPE ASSOCIATIONS

  S. Jacobsen, , Denmark 17:10 - 17:30

NEW ANTI CYTOKINE THERAPY FOR RHEUMATIC ARTHRITIS (RA)

  M. Scheinberg, Autoimmune Disease Center, Sao Paulo, Brazil 17:30 - 17:40

THE EXPANDING POTENTIAL OF GROWTH DIFFERENTIATION FACTOR-15 AS A BIOMARKER: CAN THE CYTOKINE AID TO IDENTIFY MYOSITIS OF AUTOIMMUNE ORIGIN?

  B. De Paepe1, F. Verhamme2, J. De Bleecker1, 1Ghent University Hospital, Ghent, Belgium, 2Ghent University, Ghent, Belgium

 17:40 - 17:50

THERAPEUTIC TARGETS FOR NON-INFECTIOUS UVEITIS BY CYTOKINE PROFILING IN AQUEOUS HUMOR SAMPLES

 S. Croci, M. Bonacini, A. Soriano, L. Cimino, L. De Simone, E. Bolletta, F. Gozzi, F. Muratore, M. Nicastro, L. Belloni, A. Zerbini, L. Fontana, C. Salvarani, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy

 17:50 - 18:00

CHEMOKINE RECEPTOR CCR6 INTRINSIC SIGNALING ALTERS METABOLIC REPROGRAMMING OF TH17 CELL DURING GUT INFLAMMATION AND AUTOIMMUNITY

  T. Heikrujam1, N. Kulkarni1, A. Shirolkar1, S. Rapole1, P. Sharma2, G. Lal1, 1National Centre

for Cell Science, Pune, India, 2Armed Forces Medical College (AFMC), Pune, India 18:00 - 18:10

INTERLEUKIN-33 (IL-33) AND RHEUMATOID ARTHRITIS: A MARKER OF DIAGNOSIS, PROGNOSIS AND THERAPEUTIC RESPONSE?

 A. Abou-Raya1, M. Zohairy2, A. Deghady2, M. Amer2, S. Abou-Raya2, 1Faculty of Medicine, University of Alexandria, 00203, Egypt, 2Faculty of Medicine, University of Alexandria, Alexandria, Egypt

 18:10 - 18:20

MODULATION OF CYTOKINE SECRETION OF REGULATORY B LYMPHOCYTES BY EPIGENETIC MODIFICATION OF GENOME

  A. Tchorbanov, K. Nikolova-Ganeva, Institute of microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria

 18:20 - 18:30

PROCYANIDIN B2 AMELIORATES EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (EAE) VIA SUPPRESSION OF TH17 DIFFERENTIATION BY INHIBITING NOX2 PATHWAY

 

Q. Wang1, Y.-H. Li2, Z.-C. Yang1, Q. Miao1, J.-Z. Yu2, C.-Y. Liu2, J.-J. Yin3, Z.-B. Ding4, Q.-X. Han3, L.-J. Song5, J.-J. Huang6, B.-G. Xiao7, C.-G. Ma8, 1Shanxi University of Chinese Medicine, Taiyuan, China, 2Shanxi Datong University, Datong, China, 3Shanxi University of Chinese Medicine, Tai yuan, China, 4Shanxi Medical University, Taiyuan, China, 5Shanxi University of Traditional Chinese Medicine, Taiyuan, China, 6General Hospital of Datong, Datong, China, 7Fudan University, Shanghai, China, 8Shanxi university of chinese medicine, Jinzhong, China

 370

16:30 - 18:30

PS15 -PREGNANCY AND AUTOIMMUNITY NIKOS SKALKOTAS

  Moderation: C. De Carolis, University of Rome Tor Vegata, Systems Medicine, Rome, Italy 16:30 - 16:50

IVIG IN AUTOIMMUNE RECURRENT PREGNANCY LOSS TWENTY YEARS AFTER

  C. De Carolis, University of Rome Tor Vegata, Rome, Italy 16:50 - 17:10

WHEN THE BABY IS BORN: PUERPERIUM IN PATIENTS WITH SYSTEMIC AUTOIMMUNE DISEASES

  A. Tincani, , Italy 17:10 - 17:30

INTRAVENOUS IMMUNOGLOBULIN FOR THE SECONDARY PREVENTION OF STILLBIRTH IN OBSTETRIC ANTIPHOSPHOLIPID SYNDROME: A CASE SERIES AND SYSTEMATIC REVIEW OF LITERATURE

 

M.L. Urban1, A. Bettiol2, C. Serena2, C. Comito2, I. Turrini2, S. Fruttuoso2, E. Silvestri2, I. Mattioli2, A. Vannacci2, C. Ravaldi2, F. Petraglia2, F. Mecacci2, G. Emmi2, D. Prisco2, 1University of Florence, FIRENZE, Italy, 2UNIVERSITY OF FLORENCE, FIRENZE, Italy

 17:30 - 17:40

ANALYSIS OF PREMATURE RUPTURE OF MEMBRANES IN A COHORT OF WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS FOLLOWED AT UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO

 

F. Santos1, M. Lacerda2, B. Rodrigues2, G. De Jesús3, R. Levy4, N. De Jesús3, E. Klumb2, 1uerj, rio de janeiro, Brazil, 2Universidade do Estado do rio de janeiro, Rio de Janeiro, Brazil, 3Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, 4GlaxoSmithKline, Pennsylvania, United States of America

 17:40 - 17:50

SFLT-1/PLGF RATIO IS INCREASED IN SLE PATIENTS WITH PREECLAMPSIA COMPARED TO ACTIVE NEPHRITS DURING PREGNANCY

 

G. De Jesús1, M. Lacerda2, F. Santos3, B. Rodrigues2, R. Levy4, N. De Jesús1, E. Klumb2, 1Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, 2Universidade do Estado do rio de janeiro, Rio de Janeiro, Brazil, 3uerj, rio de janeiro, Brazil, 4GlaxoSmithKline, Pennsylvania, United States of America

 17:50 - 18:00

DISEASE FLARES OF RHEUMATOID ARTHRITIS DURING PREGNANCY: WHAT IS THE IMPACT OF STOPPING BDMARDS AT THE BEGINNING OF PREGNANCY?

 

M.C. Gerardi1, A. García Fernandez2, L. Andreoli1, C. Bazzani3, M. Filippini4, M. Fredi5, R. Gorla4, M.G. Lazzaroni1, C. Nalli4, M. Taglietti4, A. Lojacono1, S. Zatti1, F. Franceschini5, A. Tincani6, 1ASST Spedali Civili, Brescia; University of Brescia, Brescia, Italy, 2Ramón y Cajal University Hospital Rheumatology, Madrid, Spain, 3ASST Spedali Civili and University of Brescia, BRESCIA, Italy, 4ASST Spedali Civili, Brescia, Brescia, Italy, 5ASST Spedali Civili, Brescia, Italy, 6 , Italy

 18:00 - 18:10

HYDROXYCHLOROQUINE (HCQ) IN PRIMARY OBSTETRICAL ANTI-PHOSPHOLIPID SYNDROME (OAPS): PROSPECTIVE STUDY OF THE EFFICACY OF HCQ IN PRIMARY OAPS

  A. Abou-Raya1, S. Abou-Raya2, 1Faculty of Medicine, University of Alexandria, 00203, Egypt, 2Faculty of Medicine, University of Alexandria, Alexandria, Egypt

 18:10 - 18:20

THE POTENTIAL ROLE OF LOW-DOSE PREDNISONE FOR THE THERAPY OF AUTOIMMUNE REPRODUCTIVE FAILURE

  M. Di Natale1, J. Carbone2, 1Hospital general Universitario Gregorio Marañon, Madrid, Spain, 2Clinica Santa Elena, Madrid, Spain

 

18:20 - 18:30

IDENTIFYING THE AETIOLOGY OF SUDDEN ACUTE ABNORMAL INVOLUNTARY MOVEMENTS IN A PRIMIGRAVID

  B. Sosa, University of the Philippines- Manila, Manila, Philippines 

38016:30 - 18:30

PS16 - CELLULAR DIAGNOSTICS IN AUTOIMMUNITY

MC3

  Moderation: Z. Vadasz1, P. Youinou2, U. Sack3, 1 , Israel, 2 , France, 3 , Germany 16:30 - 16:50

CELLULAR AND HUMORAL TESTS IN DIAGNOSIS AND MONITORING OF AUTOIMMUNE DISEASES

  U. Sack, , Germany 16:50 - 17:10

DEEP IMMUNOPHENOTYPING OF TREGS: HOW DEEP CAN YOU GO?

  S. Kordasti, King's College London, London, United Kingdom 17:10 - 17:25

FLOW CYTOMETRY IS A POWERFUL TOOL FOR THE STRATIFICATION OF AUTOIMMUNE PATIENTS.

  C. Jamin, , France 17:25 - 17:40

CXCL10 AND CXCL9 CHEMOKINES IN THE INITIATION AND PERPETUATION OF Th1 AUTOIMMUNE DISORDERS

  A. Antonelli, University of Pisa, Pisa, Italy 17:40 - 17:50

PRECISION OF AUTOANTIBODY ASSAYS IN THE BIOMEDICAL DIAGNOSTIC LABORATORIES: WHAT IS THE REAL LIFE?

 

M. Senant1, L. Musset2, G. Chyderiotis3, L. Guis-Cabanne4, J. Damoiseaux5, N. Fabien6, M.-A. Dragon-Durey1, 1Georges Pompidou European Hospital, APHP and Paris University, Paris, France, 2CHU Pitié Salpêtrière-Ch Foix, APHP, Paris, France, 3Laboratoire Eurofins Biomnis, Lyon, France, 4Laboratoire Eurofins Biomnis, Ivry-sur-Seine, France, 5Maastricht University Medical Center, Maastricht, Netherlands, 6Hospices Civils de Lyon, CHLS, Pierre-Bénite, France

 17:50 - 18:00

FEASIBILITY OF HARMONIZATION IN AUTOMATED ANA IFA TESTING: RESULTS OF THE BENELUX MULTICENTER STUDY 2019

  L. Van Hoovels1, S. Schouwers2, S. Broeders3, S. Van Den Bremt1, E. Chan4, L. Andrade5, P. Bakker-Van Liempd6, J. Beckers7, F. Bergkamp8, J. Boes9, C. Bonroy10, M. Carlier11, S. Coito12, A. Coppens13, F. Corazza14, J. Damoiseaux15, N. Daoud16, A. De Vleeschauwer17, E.

De Witte18, T. Geens19, K. Guerti20, A. Joosten21, B. Leus17, L. Lutteri22, L. Miller23, L. Mulder24, J. Murk25, A. Nijs26, A. Scohy27, T. Troch28, W. Uyttenbroeck29, H. Van Houteghem30, L. Vanneste31, M. Vercammen32, P. Verschuure33, S. Vijgen34, X. Bossuyt35, 1OLV Hospital Aalst, Aalst, Belgium, 2GZA Hospital, Antwerp, Belgium, 3Scientific Institute of Public Health, Brussels, Belgium, 4University of Florida, GAINESVILLE, United States of America, 5Universidade Federal de São Paulo, Escola Paulista de Medicina, Sao Paulo, Brazil, 6Bernhoven Hospital Uden, Uden, Netherlands, 7AZ St-Blasius Dendermonde, Dendermonde, Belgium, 8Atalmedial, Haarlem, Netherlands, 9AZ Turnhout Campus St. Jozef Turnhout, Turnhout, Belgium, 10Ghent University, Ghent, Belgium, 11Cerba Healthcare, Ghent, Belgium, 12Ketterthill Laboratories, Belvaux, Luxembourg, 13Sonic Healthcare, Antwerp, Belgium, 14CHU Brugmann, Brussels, Belgium, 15Maastricht University Medical Center, Maastricht, Netherlands, 16C.H.I.R.E.C., Braine l’Alleud, Belgium, 17Anacura, Evergem, Belgium, 18AZ Klina Brasschaat, Brasschaat, Belgium, 19Medina Group, Hasselt, Belgium, 20Antwerp University Hospital, Edegem, Belgium, 21UZ Brussels, Brussels, Belgium, 22CHU Sart-Tilman, Liège, Belgium, 23CHU-UCL Namur, Namur, Belgium, 24Medlon, Enschede, Netherlands, 25Elisabeth-Tweesteden Hospital, Tilburg, Netherlands, 26AZ Groeninge Kortrijk, Kortrijk, Belgium, 27CHU-UCL hospital-Site de Saint Luc, Brussels, Belgium, 28ASZ Aalst, Aalst, Belgium, 29ZNA Jan Palfijn-Merksem, Antwerp, Belgium, 30Maria Middelares Hospital, Ghent, Belgium, 31Medical Laboratory Bruyland Kortrijk, Kortijk, Belgium, 32AZ St-Jan Hospital, Bruges, Bruges, Belgium, 33St. Anna Hospital Geldrop, Geldrop, Netherlands, 34Jessa ziekenhuis Hasselt, Hasselt, Belgium, 35UZ Leuven, Leuven, Belgium

 18:00 - 18:10

PREVALENCE AND KINETICS OF ANTI-INFLIXIMAB ANTIBODIES DURING INFLIXIMAB THERAPY

 

D. Bertin1, C. Roman2, N. Balandraud3, J.-C. Grimaud4, S. Desplat-Jego5, 1Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, Marseille, France., Marseille, France, 2Service de Pédiatrie-AP-HM, Marseille, France, 3Service de rhumatologie -AP-HM, Marseille, France, 4Service de Gastroenterologie AP-HM, Marseille, France, 5Aix Marseille Université/ AP-HM, Marseille, France

 18:10 - 18:20

CLINICAL SIGNIFICANCE OF CYTOPLASMIC STAINING PATTERN IN ANTINUCLEAR ANTIBODY TESTING BY INDIRECT IMMUNOFLUROSENCE

  K. Mohanasundaram, N. Pooja, Saveetha Medical College Hospital, Chennai, India 18:20 - 18:30

LYMPHADENOPATHIES IN LONG-STANDING SYSTEMIC LUPUS ERYTHEMATOSUS AND THE ROLE OF MAINTENANCE THERAPY WITH RITUXIMAB.

 V. Santos1, F. Bonilla-Abadía2, N. Silva3, A. Sánchez3, I. Ruiz-Ordoñez2, G.J. Tobón2, C. Cañas3, 1Facultad de Medicina, Universidad Icesi, Cali, Colombia, 2Fundación Valle del Lili, Universidad Icesi, Cali, Colombia, 3Fundación Valle del Lili, Cali, Colombia

 385

16:30 - 18:30

PS17 - EXPERIMENTAL THERAPIES IN AUTOIMMUNITY, CANNABIS AND MORE

MC2

 Moderation: D. Rimar1, N. Mahroum2, S. Tarasov3, 1Bnai Zion medicl center, Rheumatology, Haifa, Israel, 2Sheba Medical Center, Department Of Medicine 'b', Ramat Gan, Israel, 3Materia Medica Holding, Research @ Development, Moscow, Russian Federation

 16:30 - 16:50

THE TECHNOLOGY OF ULTRA-HIGH DILUTION AS AN APPROACH TO THE TREATMENT OF AUTOIMMUNE DISEASES

 

S. Tarasov1, J. Klein-Seetharaman2, N. Van Der Meide3, G. Sherriff4, E. Kardash5, N. Petrova5, O. Epstein1, 1Materia Medica Holding, Moscow, Russian Federation, 2Colorado School of Mines, Golden, United States of America, 3U-CyTech biosciences B.V., Utrecht, Netherlands, 4Ab Biotechnology Limited, Penicuik, United Kingdom, 5Institute of General Pathology and Pathophysiology, Moscow, Russian Federation

 16:50 - 17:05

THE MEDICALIZATION OF CANNABIS FOR CLINICAL USE AND RESEARCH

  A. Afek, Sheba Medical Center, Ramat-Gan, Israel 17:05 - 17:20

CANNABIS AND AUTOIMMUNITY: POSSIBLE MECHANISMS OF ACTION

  P. Sarzi-Puttini, , Italy 17:20 - 17:35

CANNABIS THERAPY; ARE THERE SIDE EFFECTS?

  B.S. Porat, , Israel 17:35 - 17:55

IMMUNOLOGICAL CONSEQUENCES OF IMMUNE ‘RECONSTITUTION’ THERAPY IN MULTIPLE SCLEROSIS: A SYSTEMATIC REVIEW

  P. Rommer1, J. Sellner2, 1Medical University of Vienna, Vienna, Austria, 2KH Mistelbach, Mistelbach, Austria

 17:55 - 18:05

THE ROLE OF CANNABINOID OIL IN FIBROMYALGIA: CLINICAL EXPERIENCE

 A. Gkoutzourelas1, D. Athanatou2, G. Efthymiou3, D. Bogdanos1, 1University of Thessaly, Larissa, Greece, 2Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece, 3Univeristy of Thessaly, Larissa, Greece

 18:05 - 18:20

AUTOLOGOUS HEMATOLOGICAL STEM CELL TRANSPLANTATION FOR SYSTEMIC SCLEROSIS IN ISRAEL.

  D. Rimar1, Y. Butbul2, I. Rosner1, M. Rozenbaum1, G. Slobodin1, T. Zuckerman2, 1Bnai Zion medicl center, Haifa, Israel, 2Rambam medical center, Haifa, Israel

 18:20 - 18:30

THE PLACEBO AND NOCEBO EFFECTS IN THE TREATMENT WITH BIOSIMILARS

  A.R. Nogueira1, Y. Shoenfeld2, 1Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 2Sheba Medical Center, Tel Aviv, Israel

 400

16:30 - 18:30

PS18 - VACCINE AND AUTOIMMUNITY KOKKALI

 Moderation: L. Luján1, S. Čučnik2, 1University of Zaragoza, Animal Pathology, Zaragoza, Spain, 2University Medical Centre Ljubljana, Department Of Rheumatology, Ljubljana, Slovenia

 16:30 - 16:45

ASIA 500 WITH AN EMPHASIS ON THE VACCINES

  A. Watad, Sheba Medical Center, Tel-Hashomer, Israel 16:45 - 17:00

HPV VACCINATION, AUTONOMIC DYSFUNCTION AND AUTOIMMUNITY.

  S.-I. Ikeda, , Japan 17:00 - 17:15

PAPER RETRACTION - A GROWING SUPPRESSION OF MEDICAL RESEARCH ON VACCINES

 E. Elisha1, N. Ronel1, Y. Shir-Raz2, J. Guetzkow3, 1The Max Stern Yezreel Valley College, Yezreel Valley, Israel, 2The IDC Herzliya, Herzliya, Israel, 3the Hebrew University of Jerusalem, Jerusalem, Israel

 17:15 - 17:25

MACROPHAGIC MYOSFACIITIS: FROM HISTOLOGY TO CLINICS

  F.J. Authier, Paris Est Creteil University, Creteil, France 17:25 - 17:35

18F-FDG PET BRAIN IMAGING IN DYSAUTONOMIC SYNDROME AFTER HUMAN PAPILLOMA VIRUS VACCINATION

 

M. Vadalà1, A. Cistaro2, N. Quartuccio3, M.L. Calcagni4, P. Fania5, S. Margotti6, I.G. Schiera7, B. Palmieri1, 1university of modena, modena, Italy, 2ospedali galliera, genova, Italy, 3Ospedali Civico, Di Cristina e Benfratelli, palermo, Italy, 4Gemelli Hospital,, roma, Italy, 5indipendent research, torino, Italy, 6San Paolo Hospital, milano, Italy, 7indipendent research, palermo, Italy

 17:35 - 17:45

UNEXPECTED INTERACTION BETWEEN ALUMINUM-INDUCED GRANULOMAS AND SMALL RUMINANT LENTIVIRUSES: BEYOND THE

LIMITS OF THE OVINE ASIA SYNDROME

 

R. De Miguel1, I. Echeverría2, J. Asín1, A. Rodríguez-Largo1, A. Fernández1, M. Pérez1, D. De Andrés3, R. Reina4, L. Luján1, 1University of Zaragoza, Zaragoza, Spain, 2Institute of AgroBiotecnology (CSIC), Mutilva (Pamplona), Spain, 3Institute of AgroBiotechnology CSIC, Multiva (Pamplona), Spain, 4Institute of AgroBiotechnology (CSIC), Multiva (Pamplona), Spain

 17:45 - 17:55

VACCINES AND OPTIC NEURITIS – CONSEQUENCE OR COINCIDENCE?

  J. Roszkiewicz1, Y. Shoenfeld2, 1Medical University of Lodz, Łódź, Poland, 2Sheba Medical Center, Tel Aviv, Israel

 17:55 - 18:05

INSIGHTS INTO THE AUTOIMMUNE ASPECT OF PREMATURE OVARIAN INSUFFICIENCY

 K. Sharif1, A. Watad2, D. Kanduc3, H. Amital2, Y. Shoenfeld4, 1Sheba Medical Centre, Jerusalem, Israel, 2Sheba Medical Center, Tel-Hashomer, Israel, 3University of Bari, Bari, Italy, 4Sheba Medical Center, Tel Aviv, Israel

 18:05 - 18:15

VACCINATION PRACTICES AND CHRONIC DISEASE STATUS IN A COHORT OF PEDIATRIC PATIENTS IN THE UNITED STATES

  E. Mumper, Rimland Center for Integrative Medicine, Lynchburg, United States of America

 Monday 31-05-2021

41008:00 - 10:00 PL02 PLENARY SESSION ALEXANDRA

TRIANTI  Moderation: P. Youinou1, A. Doria2, G. Wick3, 1 , France, 2 , Italy, 3 , Austria 08:00 - 08:10 MAI Award Ceremony  08:10 - 08:30 MAI AWARD PLENARY WINNER - Epigenetic and transcriptional control of

Foxp3 in health and autoimmunity  V. De Rosa, , Italy 08:30 - 09:00 A NOVEL ASPECT OF “GENES X ADJUVANT” INTERACTIONS IN

AUTOIMMUNE SYNDROMES INDUCED BY ADJUVANTS  R. Gherardi, , France 09:00 - 09:30 HYPER STIMULATION OF THE IMMUNE SYSTEM AS A MAJOR CAUSE OF

AUTOIMMUNITY; CHECK POINT INHIBITORS AND SILICONE BREAST IMPLANTS AS PROOFS OF CONCEPT.

  Y. Shoenfeld, Sheba Medical Center, Tel Aviv, Israel 09:30 - 10:00 TREATMENT OF LARGE VESSEL VASCULITIS

  C. Salvarani, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy

 420

10:00 - 10:30 COFFEE BREAK, EXHIBITION, POSTERS EXHIBITION HALL430

10:30 - 12:30

PS19 - SJÖGREN’S DISEASE AND LYMPHOMA ALEXANDRA TRIANTI

  Moderation: R. Gerli1, M. Maślińska2, 1 , Italy, 2National Institute of Geriatrics, Rheumatology and Rehabilitation, Early Arthritis Clinic, Warsaw, Poland

 10:30 - 10:50

GEOEPIDEMIOLOGY OF SJÖGREN'S SYNDROME. A 2020 UPDATE.

  J.M. Anaya, , Colombia

 10:50 - 11:10

NEUROLOGICAL INVOLVEMENT IN PRIMARY SJOGREN’S SYNDROME

  R. Gerli, , Italy 11:10 - 11:20

THE EPSTEIN-BARR VIRUS INFECTION IN PRIMARY SJÖGREN’S SYNDROME

  M. Maślińska, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland

 11:20 - 11:30

RISING INCIDENCE OF SJOGREN SYNDROME? OR JUST MORE SENSITIVE CLASSIFICATION CRITERIA?

  K. Perdan Pirkmajer, J. Kramarič, N. Gašperšič, M. Tomšič, A. Hočevar, S. Praprotnik, University Medical Centre Ljubljana, Ljubljana, Slovenia

 11:30 - 11:40

PROGENITOR CELL NICHE SENESCENCE REFLECTS PATHOLOGY OF THE PAROTID SALIVARY GLAND IN PRIMARY SJÖGREN’S SYNDROME

  S. Pringle, X. Wang, S. Liefers, A. Vissink, F. Spijkervet, F. Kroese, H. Bootsma, J. Terpstra, University Medical Center Groningen, Groningen, Netherlands

 11:40 - 11:50

ELECTRIC FIELD INDUCED RELEASE AND MEASUREMENT (EFIRM), A NOVEL PLATE-BASED SALIVA ASSAY CAN DISCRIMINATE BETWEEN SJÖGREN SYNDROME AND SICCA PATIENTS

 

C. Strom1, S. Kamounah2, N. Tayob3, A. Pederson2, F. Wei4, M. Tu4, J. Cheng4, S. Rao4, Z. Feng5, D. Wong4, Y.-W. Song6, D. Chia7, 1 San Clemente, United States of America, 2University of Copenhagen, Copenhagen, Denmark, 3Harvard Medical School, Boston, United States of America, 4UCLA School of Dentistry, Los Angeles, United States of America, 5Fred Hutchinson Cancer Research Institute, Seattle, United States of America, 6Seoul National University, Seoul, Korea, Republic of, 7UCLA, Los Angeles, United States of America

 11:50 - 12:00

INVOLVEMENT OF CEREBELLUM IN PATIENTS WITH PRIMARY SJOGREN’S SYNDROME REVEALED BY THE RESTING-STATE BRAIN FUNCTION NETWORK

  B. Cui, Y. Liu, West China Hospital of Sichuan university, Chengdu, China 12:00 - 12:10

ASSOCIATION OF BAFF AND CXCL13 PERIPHERAL SOLUBLE LEVELS WITH CLINICAL PARAMETERS IN PRIMARY SJOGREN’S SYNDROME PATIENTS

  F.J. Carrillo-Ballesteros, E. Oregon-Romero, C.A. Palafox-Sánchez, Universidad de Guadalajara, Guadalajara, Mexico

 12:10 - 12:20

CHRONIC STRESS DRIVES ENDOPLASMIC RETICULUM STRESS AND ACTIVATION OF THE UNFOLDED PROTEIN RESPONSE IN MINOR SALIVARY GLAND CELLS OF PATIENTS WITH PRIMARY SJÖGREN'S SYNDROME.

 

K. Moustaka1, S. Katsiougiannis1, R. Tenta1, S. Havaki2, P. Koutsoudaki3, H. Moutsopoulos4, F. Skopouli5, 1Harokopio University Athens, Kallithea, Greece, 2University of Athens, School of Medicine, ATHENS, Greece, 3UNIVERSITY OF ATHENS, SCHOOL OF MEDICINE, ATHENS, Greece, 4 , Greece, 5none, Athens, Greece

 12:20 - 12:30

PROTON MAGNETIC RESONANCE SPECTROSCOPY (¹H-MRS) IN RHEUMATIC AUTOIMMUNE DISEASES: A SYSTEMATIC REVIEW

  R. Frittoli1, D. Pereira1, L. Rittner2, S. Appenzeller1, 1University of Campinas, Campinas, Brazil, 2UNICAMP, Campinas, Brazil

 440

10:30 - 12:30

PS20 - PRECISION (PERSONALIZED) MEDICINE IN AUTOIMMUNITY

BANQUETING

 Moderation: M. Infantino1, D. Roggenbuck2, S. Naides3, 1 , Italy, 2Medipan GmbH, General Manager, Dahlewitz / Berlin, Germany, 3Euroimmun US, a PerkinElmer company, Scientific Affairs, Mountain Lakes, United States of America

 10:30 - 10:50

MULTI-ANALYTE DETECTION PAIRED WITH AUGMENTED INTELLIGENCE ENHANCE PRECISION MEDICINE IN AUTOIMMUNITY

  M. Mahler, Inova Diagnostics, San Diego, United States of America 10:50 - 11:10

PERSONALIZED MEDICINE IN RHEUMATOID ARTHRITIS (RA)

  P.L. Meroni, IRCCS Istituto Auxlogico Italiano, Cusano Milannino - Milan, Italy 11:10 - 11:30

AUTOANTIBODIES AND THE P-VALUE MATRIX

  M. Fritzler, University of Calgary, Calgary, Canada 11:30 - 11:50

PREDICTIVE VALUE OF AUTOANTIBODIES IN RHEUMATOID ARTHRITIS (RA)

  G. Steiner, Medical University of Vienna, Vienna, Austria 11:50 - 12:10

NEW TECHNOLOGIES FOR ANTI-DSDNA ANTIBODIES DETECTION: THERE IS STILL NEED OF HARMONIZATION

  M. Infantino1, M. Manfredi2, V. Grossi2, T. Carbone3, I. Brusca4, M.G. Alessio5, G.

Previtali5, S. Platzgummer6, G. Paura7, C. Castiglione8, M. Fabris8, G. Pesce9, B. Porcelli10, L. Terzuoli10, M.R. Bacarelli10, M. Tampoia11, L. Cinquanta12, D. Villalta13, F. Buzzulini13, P. Soda14, N. Bizzaro15, 1Ospedale San Giovanni di Dio, Azienda Usl Toscana Centro, Firenze, Italy, 2San Giovanni di Dio Hospital, Azienda USL Toscana Centro, Florence, Italy, 3Ospedale San Carlo, Potenza, Italy, 4Ospedale Buccheri La Ferla FBF, Palermo, Italy, 5ASST Papa Giovanni XXIII, Bergamo, Italy, 6Ospedale Civile, Merano, Italy, 7A.O.U San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy, 8P.O. Santo Spirito, Pescara, Italy, 9IRCCS Ospedale Policlinico San Martino, Genova, Italy, 10Policlinico S. Maria alle Scotte, AOU Senese, Siena, Italy, 11Azienda Ospedaliero-Universitaria, Policlinico di Bari, Bari, Italy, 12Gruppo SYNLAB, Salerno, Italy, 13Presidio Ospedaliero S. Maria degli Angeli, Pordenone, Italy, 14University Campus Bio-Medico, Rome, Italy, 15Azienda Sanitaria Universitaria Integrata di Udine, San Donà di Piave, Italy

 12:10 - 12:20

FAST TRACK ALGORITHM: HOW TO DIFFERENTIATE A "SCLERODERMA PATTERN" FROM A "NON-SCLERODERMA PATTERN"

 

V. Smith1, A. Vanhaecke1, A. Herrick2, O. Distler3, M. Guerra4, C. Denton5, E. Deschepper6, I. Foeldvari7, M. Gutierrez8, E. Hachulla9, F. Ingegnoli10, S. Kubo11, U. Müller-Ladner12, V. Riccieri13, J. Van Laar14, M. Vonk15, U. Walker16, M. Cutolo17, 1Ghent University, Gent, Belgium, 2The University of Manchester, Salford Royal NHS Foundation Trust, Manchester, United Kingdom, 3University Hospital Zurich, Zurich, Switzerland, 4Centro Hospitalar Vila Nova de Gaia/Espinho, Vil Nova de Gaia, Portugal, 5University College London, Royal Free Hospital, London, United Kingdom, 6Ghent University, Ghent, Belgium, 7Centre for Paediatric and Adolescent Rheumatology, Hamburg, Germany, 8Instituto Nacional de Rehabilitación, Mexico City, Mexico, 9Univ. Lille, CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre de Référence des Maladies Systémiques et Auto-Immunes Rares du Nord-Ouest (CERAINO), Lille, France, 10University of Milan, Milan, Italy, 11University of Occupational and Environmental Health, Fukuoka, Japan, 12Justus-Liebig University of Giessen, Campus Kerckhoff, Bad Nauheim, Germany, 13Sapienza University of Rome, Rome, Italy, 14University Medical Center Utrecht, Utrecht, Netherlands, 15Radboud University Medical Center, Nijmegen, Netherlands, 16University Hospital Basel, Basel, Switzerland, 17Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genoa, Italy

 12:20 - 12:30

A UNIQUE TECHNOLOGY FOR THE SEROLOGICAL DIAGNOSTICS OF ANTI-DFS70 ANTIBODIES

 

M. Sowa1, C. Lode2, N. Röber3, G. Drozdenko4, R. Hiemann5, P. Schierack6, K. Conrad7, D. Roggenbuck8, 1Medipan GmbH, Senftenberg, Germany, 2Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany, 3Technical University Dresden, Dresden, Germany, 4GA Generic Assays GmbH, Senftenberg, Germany, 5BTU Cottbus-Senftenberg, Senftenberg, Germany, 6Brandenburg University of Technology Cottbus-Senftenberg Cottbus-Senftenberg, Senftenberg, Germany, 7Technical University of Dresden, Dresden, Germany, 8Medipan GmbH, Dahlewitz / Berlin, Germany

 450

10:30 - 12:30

PS21 -CNS AND AUTOIMMUNITY NIKOS SKALKOTAS

  Moderation: R. Milo, D. Karussis, , Israel 10:30 - 10:50

MENTAL HEALTH IN INFLAMMATORY ARTHRITIS: TREATMENT ACROSS THE BLOOD BRAIN BARRIER

  C. Edwards, NIHR Clinical Research Facility, University Hospital Southampton, Southampton, United Kingdom

 10:50 - 11:10

NOVEL MECHANISMS AND TREATMENT APPROACHES IN NEUROPSYCHIATRIC LUPUS

  C. Putterman, , United States of America 11:10 - 11:20

HOLISTIC CHARACTERIZATION OF THE AUTOANTIGEN REPERTOIRE IN CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY VIA AUTOANTIGENOMICS

 C. Moritz1, Y. Tholance2, O. Stoevesandt3, K. Ferraud2, J.-P. Camdessanché2, J.-C. Antoine2, 1Institut NeuroMyoGène, Saint-Étienne, France, 2CHU Saint-Étienne, Saint-Étienne, France, 3Cambridge Protein Arrays Ltd., Cambridge, United Kingdom

 11:20 - 11:30

THE PREVALENCE OF ASCA IGA AND IGG ANTIBODIES IS INCREASED IN MANIC BIPOLAR DISORDER PATIENTS

 

A. Lerner1, F. Lopez1, N. Hamdani2, C. Manier2, J.-R. Richard3, T. Matthias1, D. Bengoufa4, M. Leboyer2, R. Tamouza3, 1AESKU.GROUP, Wendelsheim, Germany, 2AP-HP, DHU Pe-PSY, Paris Est Créteil University, Creteil, France, 3AP-HP, DHU Pe-PSY, Paris Est Créteil University, Créteil, France, 4Hôpital Saint Louis, Paris, France

 11:30 - 11:40

SYSTEMIC LUPUS ERYTHEMATOSUS AND CRYPTOCOCCAL INFECTION IN THE CENTRAL NERVOUS SYSTEM

  F. Reis1, I. Gonçalves1, J. Hortolam1, L. Costallat2, S. Appenzeller2, 1Unicamp, Campinas, Brazil, 2University of Campinas, Campinas, Brazil

 11:40 - 11:50

ANTIBODIES AGAINST AMPA RECEPTOR GLUA3 SUBUNIT IN PATIENTS WITH FRONTOTEMPORAL DEMENTIA.

 

A. López-Gómez1, M.Á. Estévez1, M.A. Ballesteros1, A. García2, S. Tarongí2, D. Morell2, R. Ruíz-García3, G. Amer-Ferrer2, M.R. Julià1, 1Hospital Universitario Son Espases, Palma de Mallorca, Spain, 2Hospital Universitario Son Espases, PALMA DE MALLORCA, Spain, 3Hospital Clínic de Barcelona, Barcelona, Spain

 

11:50 - 12:00

FEAM: A NOVEL MODULATOR FOR NEUROINFLAMMATION

  E. Shavit Stein1, J. Chapman2, V. Golderman1, N. Maggio1, 1Sheba Medical Center, Ramat Gan, Israel, 2Sheba Medical Center, Israel, Ramat Gan, Israel

 12:00 - 12:10

THE PROTECTIVE EFFECT OF GINKGOLIDE K ON MYELIN SHEATH VIA PROMOTING MYELIN PHAGOCYTOSIS BY ASTROCYTES

 

Q. Miao1, Q.-X. Han2, Z.-B. Ding3, J.-J. Yin2, L.-J. Song4, J.-Z. Yu5, Q. Wang1, W.-B. Yu6, B.-G. Xiao6, C.-G. Ma7, 1Shanxi University of Chinese Medicine, Taiyuan, China, 2Shanxi University of Chinese Medicine, Tai yuan, China, 3Dept. of Neurology, Taiyuan, China, 4Shanxi University of Traditional Chinese Medicine, Taiyuan, China, 5Shanxi Datong University, Datong, China, 6Fudan University, Shanghai, China, 7Shanxi university of chinese medicine, Jinzhong, China

 12:10 - 12:20

THE GUT FEELING OF THE EYES: GUT-EYE AXIS

  A. Lerner1, C. Steigerwald2, T. Matthias1, 1AESKU.GROUP, Wendelsheim, Germany, 2AESKU.Diagnostics, Wendelsheim, Germany

 12:20 - 12:30

COMPARISON OF THE PREVEALENCE RATETHE AND DISTRIBUTION OF WHITE MATTER HYPERINTENSITYIES SIGNALS IN CIVILIAN AIRMAN AND ORDINARY PEOPLE.

  H. Liu, Beijing, China 

46010:30 - 12:30

PS22 -ASIA SYNDROME, BREAST IMPLANTS AND AUTOIMMUNITY

MC3

  Moderation: R. Gherardi1, J.W. Cohen Tervaert2, 1 , France, 2 , Canada 10:30 - 10:50

AUTOINFLAMMATORY/AUTOIMMUNITY SYNDROME INDUCED BY ADJUVANTS (SHOENFELD’S SYNDROME) DUE TO HYSTEROSCOPIC ESSURE STERILIZATION

  J.W. Cohen Tervaert1, B. Cassidy2, 1 , Canada, 2Aishling Obstetrics and Gynecology, Yorkville, United States of America

 10:50 - 11:10

GENETIC SUSCEPTIBILITY FACTORS LIMITING ALUMINUM ADJUVANTS DETOXIFICATION IN ASIA PATIENTS WITH MACROPHAGIC MYOFASCIITIS

  R. Gherardi, , France 

11:10 - 11:20

CIRCULATING ANTI-MUSCARINIC AND ANTI-ADRENERGIC RECEPTOR AUTOANTIBODIES IN PATIENTS WITH SILICONE BREAST IMPLANTS.

 

G. Halpert1, A. Watad2, H. Heidecke3, V. Ryabkova4, L. Churilov5, B. Gilburd1, M. Blank2, H. Amital2, Y. Shoenfeld6, 1Sheba Medical Center, Ramat Gan, Israel, 2Sheba Medical Center, Tel-Hashomer, Israel, 3CellTrend GmbH, Luckenwalde, Germany, 4Saint Petersburg State University, Saint Petersburg, Russian Federation, 5Laboratory of the Mosaic of Autoimmunity, Saint-Petersburg, Russian Federation, 6Sheba Medical Center, Tel Aviv, Israel

 11:20 - 11:30

ORTHOSTATIC INTOLERANCE – CAN IT BE AUTOIMMUNE ?

  Z. Lazurova, Medical faculty University Košice, Košice, Slovak Republic 11:30 - 11:40

SMALL SENSORY NERVE FIBRE INVOLVEMENT IN PATIENTS WITH LONG-LASTING MACROPHAGIC MYOFASCIITIS (MMF)

  S. Souvannanorath, Y. Baba-Amer, J.-P. Lefaucheur, F.J. Authier, Paris Est Creteil University, Creteil, France

 11:40 - 11:50

CONTRIBUTION OF THE ADJUVANT ACTIVITY OF ALUMINUM TO AUTOIMMUNITY

  A. Vojdani, Immunosciences Lab., Inc., Los Angeles, United States of America 11:50 - 12:00

INFANTILE BULLOUS PEMPHIGOID FOLLOWING HBV VACCINE: FROM CASE REPORTS TO MOLECULAR EVIDENCE.

  V. Borba1, D. Kanduc2, Y. Shoenfeld3, 1Zabludowicz Center for Autoimmune Diseases, Tel-Hashomer, Portugal, 2University of Bari, Bari, Italy, 3Sheba Medical Center, Tel Aviv, Israel

 12:00 - 12:10

TOWARDS THE ACCURATE DIAGNOSIS OF OVINE ASIA SYNDROME: DETECTION OF ALUMINUM-INDUCED, POST-VACCINATION GRANULOMAS BY COMPUTED TOMOGRAPHY IN SHEEP.

 

A. Rodríguez-Largo1, R. De Miguel1, J. Asín1, L.M. Ferrer1, E. Castells1, D. De Andrés2, M. Pérez1, R. Reina3, L. Luján1, 1University of Zaragoza, Zaragoza, Spain, 2Institute of AgroBiotechnology CSIC, Multiva (Pamplona), Spain, 3Institute of AgroBiotechnology (CSIC), Multiva (Pamplona), Spain

 12:10 - 12:20

HEAVY METALS IN AUTOIMMUNE DISEASES

 K. Sharif1, C. Bridgewood2, A. Watad3, H. Amital3, Y. Shoenfeld4, 1Sheba Medical Centre, Jerusalem, Israel, 2University of Leeds, Leeds, United Kingdom, 3Sheba Medical Center, Tel-Hashomer, Israel, 4Sheba Medical Center, Tel Aviv, Israel

 470

10:30 - 12:30

PS23 - COMPLEMENT AND NATURAL IMMUNITY MC2

 Moderation: J. Chapman1, I. Melamed2, 1Sheba Medical Center, Israel, The Zabludowicz Center For Autoimmune Disease, Ramat Gan, Israel, 2IMMUNOe Research Centers, Research, Centennial, United States of America

 10:30 - 10:50

PEDIATRIC ACUTE-ONSET NEUROPSYCHIATRIC SYNDROME ( PANS) AS A MODEL OF NEURO-IMMUNE DISEASE-THE BENEFIT OF IVIG

  I. Melamed, IMMUNOe Research Centers, Centennial, United States of America 10:50 - 11:10

THE MECHANISM OF IVIG IN NEURO-IMMUNOLOGICAL DISEASES

  S. Kaveri., cnrs, Paris, France 11:10 - 11:30

THE ROLE OF C1 ESTERASE INHIBITOR (C1INH) IN ADVERSE EVENTS RELATED TO IVIG (ADR) - THE BENEFIT OF 5% IVIG PRODUCT

  I. Melamed, IMMUNOe Research Centers, Centennial, United States of America 11:30 - 11:50

AUTOANTIBODIES TO ANNEXIN A2 AND CEREBRAL THROMBOSIS: INSIGHTS FROM A MOUSE MODEL

  J. Chapman1, E. Mindel2, R. Weiss2, D. Bushi2, E. Shavit Stein2, 1Sheba Medical Center, Israel, Ramat Gan, Israel, 2Sheba Medical Center, Ramat Gan, Israel

 11:50 - 12:00

COMPLEMENT AS HUMORAL IMMUNITY PARAMETER IN EXPERIMENTAL STRESS

 D. Labunskiy1, S. Kiryukhina2, V. Podsevatkin2, O. Zheleznikova2, V. Kolmykov2, E. Govsh2, E. Yurasova2, 1 Saransk, Russian Federation, 2Ogarev Mordovia State University, Saransk, Russian Federation

 12:00 - 12:10

COMPLEMENT VARIATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS PREGNACIES

 

F. Crisafulli1, L. Andreoli2, M. Filippini1, M. Fredi3, M.C. Gerardi2, R. Gorla1, M.G. Lazzaroni2, C. Nalli1, M. Taglietti1, A. Lojacono2, S. Zatti2, F. Franceschini3, A. Tincani4, 1ASST Spedali Civili, Brescia, Brescia, Italy, 2ASST Spedali Civili, Brescia; University of Brescia, Brescia, Italy, 3ASST Spedali Civili, Brescia, Italy, 4 , Italy

 12:10 - 12:20

COMPLEMENTEMIA IN PREGNANCIES WITH ANTIPHOSPHOLIPID SYNDROME

 S. De Carolis1, S. Tabacco2, C. Garufi2, A. Caneschi3, S. Salvi3, A. Giannini2, A. Botta3, A. Lanzone3, 1Fondazione Policlinico Gemelli IRCCS , Rome, Italy, 2"Sapienza" Università di Roma, Rome, Italy, 3Fondazione Policlinico Gemelli IRCCS, Rome, Italy

 12:20 - 12:30

IS HYPOCOMPLEMENTEMIA ASSOCIATED WITH WORSE PROGNOSIS IN RA?

 F. Lozano-Morillo1, O. Cabrera-Marante2, D. Pleguezuelo2, P. Lavilla Villar3, M. Retuerto Guerrero3, L. Morillas3, A. Serrano2, 1Hospital 12 de octubre, Madrid, Spain, 2Hospital doce de octubre, madrid, Spain, 3Hospital Universitario 12 de Octubre, madrid, Spain

 480

10:30 - 12:30

PS24 - MAI AWARD KOKKALI

 10:30 - 10:40

OPENING WORDS

  10:40 - 10:50

ATYPIC POSTTRANSLATIONALLY MODIFIED AUTOANTIGENS AS IMMUNOGENIC DRIVERS OF B-CELL-NEOPLASMS

  L. Thurner1, M. Bewarder1, N. Fadle1, E. Regitz1, S. Hartmann2, K.-D. Preuss1, 1Saarland Medical School, Homburg/Saar, Germany, 2Goethe University, Frankfurt, Germany

 10:50 - 11:00

DEREGULATION OF REGULATORY T CELLS: A CRITICAL ROLE OF NUCLEAR FACTOR OF ACTIVATED T CELLS AND FORKHEAD BOX P3 IN GENERALIZED VITILIGO

  M. Dwivedi1, P. Giri1, R. Begum2, A. Bharti3, 1Uka Tarsadia University, Bardoli, India, 2The Maharaja Sayajirao University of Baroda, Vadodara, India, 3General Hospital, Vyara, India

 11:00 - 11:10

ANTI-CARBAMYLATED PROTEINS ANTIBODIES LEVELS AS PREDICTOR OF CLINICAL RESPONSE TO ABATACEPT IN RHEUMATOID ARTHRITIS.

 S. Piantoni1, M. Boldini1, E. Garrafa2, C. Bazzani1, M. Fredi3, I. Cavazzana3, A. Tincani1, F. Franceschini3, 1ASST Spedali Civili and University of Brescia, BRESCIA, Italy, 2University of Brescia, Brescia, Italy, 3ASST Spedali Civili, Brescia, Italy

 11:10 - 11:20

AGE-ASSOCIATED IGD-CD27- DOUBLE NEGATIVE (DN) B CELLS WITH A PRO-INFLAMMATORY PHENOTYPE AND FUNCTION ARE ABNORMALLY ELEVATED IN MULTIPLE SCLEROSIS PATIENTS

 L. Beckers1, G. Montes Diaz1, L. Villar2, B. Van Wijmeersch3, V. Popescu3, V. Somers1, J. Fraussen1, 1Hasselt University, Diepenbeek, Belgium, 2Hospital Universitario Ramón y Cajal, Madrid, Spain, 3Rehabilitation & MS-Center, Pelt, Belgium

 490

10:30 - 12:30

PS25 - AUTOIMMUNITY IN BARCELONA CLINIC, ALUMNI SESSION

CONFERENCE ROOM 1

 Moderation: B. Pons-Estel1, R. Cervera2, 1Regional Center for Autoimmune and Rheumatic Diseases - GO-CREAR, Rheumatology, Rosario, Argentina, 2Hospital Clinic Barcelona, Catalonia, Barcelona, Spain

 10:30 - 10:40

INTRODUCTION

  R. Cervera, Hospital Clinic Barcelona, Barcelona, Spain 10:40 - 10:50

DISEASE PHENOTYPE IN ANCA ASSOCIATED VASCULITIS.

  F. Silva, C. Pinto, A. Barbosa, E. Pereira, I. Ferreira, R. Neto, E. Mariz, J. Almeida, Centro Hospitalar São João, Porto, Portugal

 10:50 - 11:00

NEW INSIGHTS IN CRYOGLOBULINEMIC VASCULITIS

  F. Silva1, C. Pinto1, A. Barbosa1, T. Borges2, J. Almeida1, 1Centro Hospitalar São João, Porto, Portugal, 2Hospital Privado de Gaia, Gaia, Portugal

 11:00 - 11:10

CAN ANTICOAGULATION BE WITHDRAWN IN ANTIPHOSPHOLIPID SYNDROME PATIENTS WHOSE ANTIPHOSPHOLIPID ANTIBODIES BECOME PERSISTENTLY NEGATIVE? A SYSTEMATIC REVIEW.

 

E. Coloma1, G. Espinosa2, C. Yelnik3, M. Lambert3, R. Cervera4, 1Hospital Clínic, Barcelona, Spain, 2Hospital Clinic, Barcelona, Spain, 3Centre National de Référence des Maladies Systémiques Rares, Hôpital Claude Huriez, Lille, France, 4Hospital Clinic Barcelona, Barcelona, Spain

 11:10 - 11:20

PAUCI-IMUNE GLOMERULONEPHRITIS IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

 E. Alves1, A. Garcia2, G. Espinosa2, L. Quintana3, R. Cervera4, 1Hospital Clínic, Barcelona, Catalonia, Spain., Braga, Portugal, 2Hospital Clinic, Barcelona, Spain, 3University of Barcelona, Barcelona, Spain, 4Hospital Clinic Barcelona, Barcelona, Spain

 11:20 - 11:30

COMBINATION VASODILATOR THERAPY IMPROVES SKIN MICROVASCULAR BLOOD BUT DO NOT RESTORE ENDOTHELIAL FUNCTION IN SYSTEMIC SCLEROSIS

  C. Laurent, G. Hariri, J.-R. Lavillegrand, S. Rivière, J. Joffre, B. Guidet, O. Fain, A. Mekinian, H. Ait Oufella, Hopital saint-antoine, Paris, France

 11:30 - 11:40

EMERGING PD-1 AND PD-1L INHIBITORS-ASSOCIATED MYOPATHY WITH A CHARACTERISTIC HISTOPATHOLOGICAL PATTERN

 A. Matas Garcia1, J. Milisenda1, A. Selvo-O'Callaghan2, S. Prieto-González1, J. Padrosa1, J. Maria Grau1, E. Trallero-Araguas3, 1Hospital Clínic de Barcelona, Barcelona, Spain, 2Hospital Vall d'Hebron, Barcelona, Spain, 3Hospital Vall d'Hebrón, Barcelona, Spain

 11:40 - 11:50

CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME PRESENTING WITH AORTIC BARRAGE: CASE REPORT AND REVIEW OF THE LITERATURE

  L. Moroni1, G. Mancuso1, P. Righini2, G. Ramirez1, E. Bozzolo1, L. Dagna1, 1San Raffaele Scientific Institute, Milano, Italy, 2IRRCS Policlinico San Donato, San Donato (Milan), Italy

 11:50 - 12:00

METABOLIC SYNDROME AND SYSTEMIC SCLEROSIS

 F. Atzeni1, C. Casuscelli1, F. Marino1, M. Cirillo1, A. Alciati2, 1Rheumatology Unit, Messina, Italy, 2Department of Clinical Neurosciences, Hermanas Hospitalarias, Villa S. Benedetto Menni Hospital, Albese (Como),, Messina, Italy

 12:00 - 12:10

EFFICACY OF ECULIZUMAB IN CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME: DESCRIPTIVE ANALYSIS FROM THE “CAPS REGISTRY

 

B. Lopez-Benjume1, I. Rodriguez Pintó2, M.C. Amigo3, Y. Shoenfeld4, G. Espinosa1, R. Cervera5, 1Hospital Clinic, Barcelona, Spain, 2Hospital Universitari Mutua de Terrassa, Terrassa, Spain, 3Centro Médico ABC, México, Mexico, 4Sheba Medical Center, Tel Aviv, Israel, 5Hospital Clinic Barcelona, Barcelona, Spain

 12:10 - 12:20

ANALYSIS OF THE TERMINOLOGY USED IN PATIENTS WITH LUPUS MANIFESTATIONS WHO DO NOT MEET THE CLASSIFICATION CRITERIA AND THEIR APPLICABILITY IN UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE

 

C.E. Toro Gutierrez1, A. Suarez Avellaneda2, J.M. Anaya3, R. Cervera4, 1Centro de Referencia en Osteoporosis & Reumatología, Cali, Colombia, 2Centro de Estudio de Enfermedades Autoinmunes - CREA, Bogotá, Colombia, 3 , Colombia, 4Hospital Clinic Barcelona, Barcelona, Spain

 12:20 - 12:30

Q&A

  

49212:30 - 14:00

LUNCH BREAK, EXHIBITION, POSTERS EXHIBITION HALL

49512:30 - 14:00

INDUSTRY SUPPORTED SESSION NIKOS SKALKOTAS

 12:30 - 12:30

WORKSHOP IS ORGANIZED AND SUPPORTED BY Inova

  

50014:00 - 16:00

PS26 -NOVELTIES IN SYSTEMIC SCLEROSIS ALEXANDRA TRIANTI

  Moderation: L. Mouthon1, M. Mettuci Cerinic2, 1 , France, 2Div. Rheumatology, University Of Florence, Italy

 14:00 - 14:20

DIFFERENTIAL DIAGNOSIS OF SCLERODERMA AND PSEUDOSCLERODERMA

  L. Mouthon, , France 14:20 - 14:40

STRATIFICATION AND PREDICTION OF PROGRESSION OF SSC-ILD

  M. Mettuci Cerinic, Div. Rheumatology, , Italy 14:40 - 15:00

ANTI-ANGIOTENSIN RECEPTOR ANTIBODIES AS CAUSAL DRIVERS FOR SYSTEMIC SCLEROSIS

  G. Riemekasten, , Germany 15:00 - 15:10

SYSTEMIC SCLEROSIS SUSCEPTIBILITY IN THE GREEK-CYPRIOT POPULATION: A PILOT STUDY

 

P. Chairta1, S. Psarelis2, K. Michailidou3, S. Symeonidou2, P. Nicolaou4, K. Christodoulou4, 1Cyprus School of Molecular Medicine and The Cyprus Institute of Neurology and Genetics, NICOSIA, Cyprus, 2Nicosia General Hospital, Nicosia, Cyprus, 3Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus, 4The Cyprus Institute of Neurology and Genetics and Cyprus School of Molecular Medicine, Nicosia, Cyprus

 15:10 - 15:20

SKIN ANTI-FIBROSIS EFFECT OF CIPLUKAN HERB (PHYSALIS ANGULATA LINN) IN SYSTEMIC SCLEROSIS (A DOUBLE BLIND RANDOMIZED CONTROLLED TRIAL)

  S. Dewi1, H. Isbagio2, N. Kertia3, E. Purwaningsih4, 1Dr. Hasan Sadikin Hospital/Indonesian Rheumatology Association, Bandung, West Java, Indonesia, 2Dr. Ciptomangunkusumo Hospital/University of Indonesia, Jakarta Pusat, Indonesia, 3Dr. Sardjito Hospital/University

of Gadjah Mada, Yogyakarta, Indonesia, 4University of Indonesia, Jakarta Pusat, Indonesia 15:20 - 15:30

MYOFIBROBLAST CELLS EXPRESSION OF CD248 MAY CONTRIBUTE TO EXACERBATE MICROVASCULAR DAMAGE DURING SYSTEMIC SCLEROSIS

 P. Cipriani1, P. Di Benedetto1, R. Ross2, V. Liakouli1, P. Ruscitti1, O. Berardicurti1, N. Panzera1, N. Grazia1, G. Marvia2, F. Del Galdo2, R. Giacomelli1, 1University of L'Aquila, L'Aquila, Italy, 2University of Leeds, Leeds, United Kingdom

 15:30 - 15:40

MIR-29A PLAYS A CRUCIAL ROLE IN THE THERAPEUTIC EFFECT OF ASC-DERIVED EXTRACELLULAR VESICLES IN SYSTEMIC SCLEROSIS

  P. Rozier1, M. Maumus2, A. Maria1, C. Jorgensen2, D. Noël2, P. Guilpain1, 1Montpellier University Hospital, Montpellier, France, 2Inserm, Montpellier, France

 15:40 - 15:50

HIGH PREVALENCE OF MALNUTRITION IN SYSTEMIC SCLEROSIS: RESULTS FROM A FRENCH MONOCENTRIC COHORT STUDY

 A. Maria1, V. Rivet1, S. Rivière1, R. Goulabchand1, B. Suzon1, P. Henneton1, L. Partouche1, P. Rullier1, A. Schiffmann1, N. Flori2, P. Senesse2, A. Sultan1, P. Guilpain1, 1Montpellier University Hospital, Montpellier, France, 2Intitute of Cancer Montpellier, Montpellier, France

 510

14:00 - 16:00

PS27 - BREAKTHROUGH IN THERAPY OF AUTOIMMUNE DISEASES

BANQUETING

  Moderation: N.L. Bragazzi1, M. Blank2, M. Schneider3, 1 Genoa, Italy, 2 , Israel, 3 , Germany 14:00 - 14:20

NOVEL THERAPIES – CHECKPOINT INHIBITORS, BIOSIMILARS, CANNABIS, MUSIC

  M. Scheinberg, Autoimmune Disease Center, Sao Paulo, Brazil 14:20 - 14:35

HELMINTHES BASED DERIVATIVE TO TREAT AUTOIMMUNITY; TPC A NOVEL BI-FUNCTIONAL IMMUNOMODULATORY COMPOUND

  M. Blank1, Y. Shoenfeld2, 1Sheba Medical Center, Tel-Hashomer, Israel, 2Sheba Medical Center, Tel Aviv, Israel

 14:35 - 14:55

EXPECTATIONS AS DRIVERS OF THERAPEUTIC RESPONSE

  M. Schneider, , Germany 14:55 - 15:10

EFFECTS OF JAK INHIBITION ON BONE METABOLISM AND OSTEOPOROSIS IN RHEUMATOID ARTHRITIS

  Z. Szekanecz, , Hungary 15:10 - 15:20

MECHANISTIC CLASSIFICATION OF IMMUNE CHECKPOINT INHIBITOR TOXICITY AS A POINTER TO MINIMAL TREATMENT STRATEGIES TO FURTHER IMPROVE SURVIVAL

  D. Mcgonagle1, N.L. Bragazzi2, H. Amital3, A. Watad3, 1Leeds University, Leeds, United Kingdom, 2University of Genoa, Genoa, Italy, 3Sheba Medical Center, Tel-Hashomer, Israel

 15:20 - 15:30

OPTINEURIN IN SYNOVIAL FIBROBLASTS PROTECTS THE JOINT BY SUPPRESSING OSTEOCLASTOGENESIS IN RHEUMATOID ARTHRITIS

  M. Kato, W.S. Lee, M. Kono, Y. Fujieda, K. Oku, S. Yasuda, O. Amengual, T. Atsumi, Hokkaido University, Sapporo, Japan

 15:30 - 15:40

PREVALENCE AND PATHOGENICITY OF AUTOANTIBODIES IN IDIOPATHIC CD4 LYMPHOPENIA

  I. Sereti1, C.-S. Wong2, X. Liu2, H. Mystakelis2, A. Perez-Diez2, 1National Institutes of Health, Bethesda, United States of America, 2NIH, Bethesda, United States of America

 15:40 - 15:50

FUNCTIONAL ELIMINATION OF AUTOREACTIVE T AND B CELLS BY ANTI-ANNEXIN A1 ANTIBODY THERAPY IN MRL/LPR MURINE MODEL OF SYSTEMIC LUPUS ERYTHEMATOSUS

 

A. Tchorbanov1, S. Bradyanova1, N. Mihaylova1, P. Chipinski1, J. Prechl2, D. Kyurkchiev3, 1Institute of microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria, 2Hungarian Academy of Sciences, Budapest, Hungary, 3Medical University of Sofia (Bulgaria), University Hospital “St. Ivan Rilski”, Laboratory of Clinical Immunology, Sofia, Bulgaria

 15:50 - 16:00

EFFICACY AND SAFETY OF SUBCUTANEOUS TOCILIZUMAB FOR THYROID EYE DISEASE

  J. Carbone1, M. Di Natale2, E. Sarmiento1, 1Clinica Santa Elena, Madrid, Spain, 2Hospital general Universitario Gregorio Marañon, Madrid, Spain

 530

14:00 - 16:00

PS28 -AUTOIMMUNITY AND THE KIDNEYS NIKOS SKALKOTAS

 

Moderation: D. Roccatello1, S. Kivity2, 1SCU Nephrology and Dialysis & Center of Research of Immunopathology and Rare Diseases - Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, Department Of Clinical And Biological Sciences, Turin, Italy, 2Sheba Medical Center, Zabludowicz Center For Autoimmune Diseases, Tel-Hashomer, Israel

 14:00 - 14:20

MANAGEMENT OF AUTOINFLAMMATORY DISEASES WITH RENAL INVOLVEMENT

  S. Sciascia, University of Torino, Torino, Italy 14:20 - 14:40

MANAGEMENT OF VASCULITIS WITH RENAL INVOLVEMENT

  R. Fenoglio, , Italy 14:40 - 15:00

THE CURRENT STATUS AND RECENT DEVELOPMENTS IN THE DETECTION OF ANTI-PLA2R AUTOANTIBODIES IN PRIMARY MEMBRANOUS NEPHROPATHY

  E. Hoxha, University Medical Center Hamburg-Eppendorf, Hamburg, Germany 15:00 - 15:15

METABOLIC CONTROL AND THERAPEUTIC TARGETING OF MTOR-DEPENDENT T-CELL LINEAGE SPECIFICATION IN AUTOIMMUNITY"

  A. Perl, SUNY, Syracuse, United States of America 15:15 - 15:30

CANCER, INFLAMATION AND AUTOIMMUNITY

  A. Makatsariya, , Russian Federation 15:30 - 15:40

IMPLEMENTATION OF ANTI-PHOSPHOLIPASE A2 RECEPTOR DETECTION BY ELISA AND ITS DIAGNOSTIC AND CLINICAL VALUE IN PRIMARY MEMBRANOUS GLOMERULONEPHRITIS

  D. Heredero Jung1, A. Rodríguez Campón2, M.B. Aparicio Hernández2, G. Tabernero Fernández2, 1 Salamanca, Spain, 2University Hospital of Salamanca, Salamanca, Spain

 15:40 - 15:50

THE ROLE OF ICOS/ICOS-L COSTIMULATORY PATHWAY IN LUPUS NEPHRITIS: A NEW BIOMARKER AND THERAPEUTIC TARGET?

 

M. Quaglia1, M. Mazzariol2, G. Merlotti2, G. Cappellano3, A. Chiocchetti2, U. Dianzani2, V. Cantaluppi2, 1 TORINO, Italy, 2Center for Traslational Research on Autoimmune and Allergic Disea se—CAAD, University of Eastern Piedmont, Novara, Italy, 3University of Piemonte Orientale UPO, Novara, Italy

 15:50 - 16:00

THE EFFECT OF ENVIRONMENT ON CYTOKINE PRODUCTION IN PATIENT WITH PRIMARY MEMBRANOUS NEPHROPATHY

 M. Cremoni1, V. Brglez2, V. Esnault3, B. Seitz-Polski2, 1CHU Pasteur 2, NICE, France, 2Hôpital l'Archet, Université Côte d'Azur, NICE, France, 3Hôpital Pasteur 2, Université Côte d'Azur, NICE, France

 540

14:00 - 16:00

PS29 -EASI SESSION- HARMONIZATION IN AUTOANTIBODY TESTING: FROM TEST RESULT TO REPORTING AND INTERPRETATION

MC3

  Moderation: X. Bossuyt1, J. Damoiseaux2, 1 , Belgium, 2Maastricht University Medical Center, Central Diagnostic Laboratory, Maastricht, Netherlands

 14:00 - 14:20

NEW WHO REFERENCE MATERIAL FOR ANTI-DSDNA ANTIBODIES: IMPLEMENTATION IN CLINICAL PRACTICE

  J. Rönnelid, Uppsala University, Uppsala, Sweden 14:20 - 14:40

HOW TO DEFINE THE OPTIMAL CUT-OFF FOR AN AUTOANTIBODY ASSAY

  J. Faro Viana, , Portugal 14:40 - 15:00

LIKELIHOOD RATIOS AS VALUE PROPOSITION FOR DIAGNOSTIC LABORATORY TESTS

  W. Fierz, , Switzerland 15:00 - 15:20

HARMONIZATION OF TEST RESULT INTERPRETATION

  X. Bossuyt, , Belgium 15:20 - 15:30

STRATEGY FOR CUT-OFF SETTING, STANDARDISATION AND HARMONISATION BY EUROIMMUN

  O. Sendscheid, EUROIMMUN Medizinische Labordiagnostika AG, Lübeck,, Germany 15:30 - 15:40

STRATEGY FOR CUT-OFF SETTING, STANDARDISATION AND HARMONISATION BY INOVA/WERFEN

  R. Albesa, Inova Diagnostics, San Diego, United States of America 15:40 - 15:50

STRATEGY FOR CUT-OFF SETTING, STANDARDISATION AND HARMONISATION BY MEDIPAN/GENERIC ASSAYS

  D. Roggenbuck, Medipan GmbH, Dahlewitz / Berlin, Germany 15:50 - 16:00

STRATEGY FOR CUT-OFF SETTING, STANDARDISATION AND HARMONISATION BY THERMO FISHER

  N. Olschowka, Phadia GmbH, Freiburg, Germany

 550

14:00 - 16:00

PS30 - RHEUMATIOD ARTHRITIS, PSORIASIS AND PSORIATIC ARTHRITIS

MC2

  Moderation: R. Perricone1, M. Cutolo2, 1 , Italy, 2University of Genova, Rheumatology Dept Internal Medicine, Genova, Italy

 14:00 - 14:20

THE ROLE OF AUTOIMMUNITY IN THE PATHOGENESIS OF PSORIATIC ARTHRITIS

  R. Perricone, , Italy 14:20 - 14:40

THE BALANCE M1/M2 IN RHEUMATOID ARTHRITIS: RECENT INSIGHTS 

  M. Cutolo, Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genoa, Italy

 14:40 - 14:50

PROTEIN NETWORK AND PATHWAY ANALYSIS IN A PHARMACOGENETIC STUDY OF CYCLOSPORINE TREATMENT RESPONSE IN GREEK PATIENTS WITH PSORIASIS

 

E. Stavrou1, E. Evangelou2, A. Liaropoulos1, D. Digka1, E. Zafiriou3, A. Roussaki-Schulze3, A. Patsatsi4, D. Sotiriadis4, S. Georgiou1, N. Moschonas1, Y. Vasilopoulos1, 1University of Patras, Rion, Greece, 2University of Ioannina, Ioannina, Greece, 3University of Thessaly, Larissa, Greece, 4Aristotle University, Thessaloniki, Greece

 14:50 - 15:00

SECUKINUMAB RELATED GASTROINTESTINAL SAFETY IN PSORIATIC ARTHRITIS (PSA) AND ANKYLOSING SPONDYLITIS (AS)

 

I. Onac1, C. Tacu1, B. Clarke2, M. Lloyd3, V. Hajela1, T. Batty1, J. Thoroughgood4, S. Smith3, H. Irvine5, D. Hill6, G. Baxter7, N. Horwood7, S. Mahendrakar7, R. Rajak7, S. Griffith4, P. Kiely6, J. Galloway2, 1Brighton and Suseex University Hospital, Brighton, United Kingdom, 2King's College London, London, United Kingdom, 3Frimley Park Hospital, Frimley, United Kingdom, 4East Surrey Hospital, Redhill, United Kingdom, 5Royal Berkshire NHS Foundation Trust, Reading, United Kingdom, 6St George's University Hospitals NHS Foundation Trust, London, United Kingdom, 7Croydon University Hospital, Croydon, United Kingdom

 15:00 - 15:10

RELATIVE TELOMERE LENGTH IN PATIENTS WITH RHEUMATOID ARTHRITIS AT EARLY STAGE AND DISEASE FOLLOW-UP

  Y. Svyryd1, V. Pascual-Ramos1, I. Contreras-Yañez1, L. Muñoz-Téllez1, L. Luna-Muñoz1, M. López-Hernández1, A. Aguayo-Gómez1, O. Mutchinick2, 1INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN SALVADOR ZUBIRÁN, MEXICO CITY, Mexico, 2INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y

NUTRICIÓN SALVADOR ZUBIRÁN, MEXICO CITY, Mexico 15:10 - 15:20

ANGIOGENESIS PLAYS A MAJOR ROLE IN PANNUS FORMATION AND ORGANIZATION DURING RHEUMATOID ARTHRITIS

 R. Giacomelli, P. Di Benedetto, P. Ruscitti, O. Berardicurti, V. Liakouli, F. Carubbi, N. Panzera, N. Grazia, M. Di Vito Nolfi, A. Maurizi, N. Rucci, F. Zazzeroni, P. Cipriani, University of L'Aquila, L'Aquila, Italy

 15:20 - 15:30

NOVEL AUTOANTIBODY BIOMARKERS FOR THE PREDICTION OF THERAPY RESPONSE IN RHEUMATOID ARTHRITIS

  P. Vandormael1, P. Ruytinx1, A. Pues1, S. Loyens1, P. Verschueren2, V. Somers3, 1UHasselt, Hasselt, Belgium, 2KULeuven, Leuven, Belgium, 3Hasselt University, Diepenbeek, Belgium

 15:30 - 15:40

SEARCH FOR ENVIRONMENTAL AND INDIVIDUAL RHEUMATOID ARTHRITIS DRIVERS AND RISK FACTORS IN THE TATARSTAN’S WOMEN COHORT

 

M. Arleevskaya1, R. Larionova1, O. Kravtsova1, E. Shagimardanova2, S. Validov2, A. Valeeva2, E. Boulygina2, E. Takha2, E. Shuralev2, M. Mukminov2, G. Kazarian2, Y. Renaudineau3, 1Medical School of Kazan, Kazan, Russian Federation, 2University of Kazan, Kazan, Russian Federation, 3Brest University Medical School, Brest, France

 15:40 - 15:50

MICA AND NKG2D POLYMOPPHISM IN GREEK PATIENTS WITH RHEUMATOID ARTHRITIS

 

K. Tarassi1, J. Wielińska2, E. Mole3, M. Iwaszko2, V. Kitsiou1, D. Kouniaki1, T. Athanassiades1, K. Bogunia-Kubik2, A. Tsirogianni4, 1Evangelismos General Hospital, Athens, Greece, 2Polish Academy of Sciences, Wroclaw, Poland, 3Evangelismos Hospital, Athens, Greece, 4Evaggelismos General Hospital , Athens, Greece

 15:50 - 16:00

NEGATIVE PROGNOSTIC FACTORS OF TREATMENT FAILURE IN RHEUMATOID ARTHRITIS: EXPLORING AUTOIMMUNE THYROID DISORDERS

 P. Conigliaro1, G. Fonti1, A. D’Antonio1, L. D’Erme1, M.S. Chimenti1, P. Triggianese1, R. Perricone2, 1Rheumatology, Allergy and Clinical Immunology, University of Rome Tor Vergata, Rome, Italy, 2 , Italy

 555

14:00 - 16:00

PS31 - DIAGNOSTIC MEASUREMENTS IN AUTOIMMUNITY

KOKKALI

  Moderation: M.-J. Sousa1, G. Steiner2, 1centro de medicina laboratorial germano de sousa, Laboratory Medicine, lisbon, Portugal, 2 , Austria

 14:00 - 14:15

PREDICTION AND PREVENTION OF RHEUMATOID ARTHRITIS

  M. Mahler, Inova Diagnostics, San Diego, United States of America 14:15 - 14:30

ANTINUCLEAR ANTIBODY TESTING BY INDIRECT IMMUNOFLUORESCENCE AND BY SOLID PHASE ASSAY

  X. Bossuyt, UZ Leuven, Leuven, Belgium 14:30 - 14:40

ANTI-Β2GPI DOMAIN I IN TWO OPPOSITE ANTIPHOSPHOLIPID ANTIBODY PROFILES.

 Y. Jiménez De Las Pozas1, N. Casado2, M. Dávila2, M. Raba2, M.C. Vegas-Sánchez2, M.J. Martínez-Becerra1, K. Guzmán López2, 1Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, 2Fundación Jiménez Díaz University Hospital, Madrid, Spain

 14:40 - 14:50

THE EFFECT OF PROTEINURIA ON ANTINUCLEAR ANTIBODY ASSAY RESULTS IN PATIENTS WITH GLOMERULONEPHRITIS

  S. Sarfaraz, , Greece 14:50 - 15:00

ANTIBODIES TO RO AUTOANTIGENS: DIAGNOSTIC, CLINICAL AND SEROLOGICAL ASSOCIATIONS

  E. Zampeli1, M. Mavrommati2, H. Moutsopoulos3, F. Skopouli4, 1 Athens, Greece, 2Euroclinic of Athens, Athens, Greece, 3 , Greece, 4none, Athens, Greece

 15:00 - 15:10

A POSSIBLE NOVEL BIOMARKER IN AUTOIMMUNE DISEASES

 

C. Napodano1, F. Gulli2, M. Marino3, G. Ciasca4, K. Pocino5, V. Basile6, A. Stefanile4, U. Basile4, G.L. Rapaccini5, 1Risultati di ricerca Risultato web con link ai siti Policlinico Universitario Fondazione Agostino Gemelli, Rome, Italy, 2Ospedale Madre Giuseppina Vannini, Rome, Italy, 3Catholic University of the Sacred Heart, Rome, Italy, 4Fondazione Policlinico A.Gemelli, IRCCS, Rome, Italy, 5Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy, 6Università di TorVergata, Rome, Italy

 15:10 - 15:20

AN INTERNATIONAL SURVEY ON METHODOLOGICAL ASPECTS OF ANTI-NUCLEAR ANTIBODY TESTING BY INDIRECT IMMUNOFLUORSCENCE ANALYSIS: CURRENT PRACTICES FOR INTERNAL QUALITY CONTROL.

  M. Vercammen1, C. Bonroy2, S. Broeders3, L. Andrade4, N. Bizzaro5, D. Bogdanos6, E. Chan7, W. Coucke1, J. Damoiseaux8, W. De Melo Cruvinel1, A. Kozmar9, L. Kuhi10, L. Lutteri11, M.J. Rego De Sousa12, S. Schouwers13, L. Van Hoovels14, X. Bossuyt15, 1AZ St-Jan

Hospital, Bruges, Bruges, Belgium, 2Ghent University, Ghent, Belgium, 3Scientific Institute of Public Health, Brussels, Belgium, 4Universidade Federal de São Paulo, Escola Paulista de Medicina, Sao Paulo, Brazil, 5Azienda Sanitaria Universitaria Integrata di Udine, San Donà di Piave, Italy, 6University of Thessaly, Larissa, Greece, 7University of Florida, GAINESVILLE, United States of America, 8Maastricht University Medical Center, Maastricht, Netherlands, 9University Hospital Centre Zagreb, Zaghreb, Croatia, 10East Tallin Central Hospital, Tallin, Estonia, 11CHU Sart-Tilman, Liège, Belgium, 12Centro de Medicina Laboratorial Germano de Sousa, Lisboa, Portugal, 13GZA Hospital, Antwerp, Belgium, 14OLV Hospital Aalst, Aalst, Belgium, 15UZ Leuven, Leuven, Belgium

 15:20 - 15:30

PRE-ANALYTICAL EVALUATION OF CIRCULATING CALPROTECTIN IN SERUM AND PLASMA FROM HEALTHY DONORS

 

M. Infantino1, M. Manfredi2, V. Grossi2, J. Memmolo3, R. Albesa3, E. Fitzgerald3, M. Benucci2, F. Li Gobbi2, A. Matucci2, F. Sarra4, M. Mahler3, 1Ospedale San Giovanni di Dio, Azienda Usl Toscana Centro, Firenze, Italy, 2San Giovanni di Dio Hospital, Azienda USL Toscana Centro, Florence, Italy, 3Inova Diagnostics, San Diego, United States of America, 4Werfen, Milano, Italy

 15:30 - 15:40

DEVELOPMENT AND EVALUATION OF I-TRACKER KITS: FAST AND INNOVATIVE CHEMILUMINESCENT ASSAYS FOR THE MONITORING OF PATIENTS TREATED WITH INFLIXIMAB AND ADALIMUMAB

  S. Daviere, G. Noguier, C. Montaillier, L. Colombeau, E. Parussini, Theradiag, Croissy-Beaubourg, France

 15:40 - 15:50

ANTI-PHOSPHATIDYLSERINE/PROTHROMBIN ANTIBODIES AND LUPUS ANTICOAGULANT DO NOT RECOGNIZE THE SAME TYPE OF PATIENTS: THE ADDED VALUE OF ANTI-PHOSPHATIDYLSERINE/PROTHROMBIN DETERMINATION.

 

A. Serrano1, O. Cabrera-Marante1, D. Pleguezuelo1, L. Naranjo2, R. Díaz-Simón3, M. Serrano4, 1Hospital doce de octubre, madrid, Spain, 2Hospital Universitario 12 de Octubre, MADRID, Spain, 3Hospital 12 de Octubre, Madrid, Spain, 4Hospital Clinico San Carlos, madrid, Spain

 15:50 - 16:00

MAY CAPILLAROSCOPY BE A CANDIDATE TOOL IN FUTURE ALGORITHMS FOR SSC-ILD: ARE WE LOOKING FOR THE HOLY GRAIL? A SYSTEMATIC REVIEW

 

V. Smith1, A. Vanhaecke1, M. Guerra2, K. Melsens1, E. Vandecasteele3, S. Paolino4, M. Cutolo5, 1Ghent University, Gent, Belgium, 2Centro Hospitalar Vila Nova de Gaia/Espinho, Vil Nova de Gaia, Portugal, 3Ghent University Hospital, Gent, Belgium, 4University of Genoa, IRCCS San Martino Polyclinic Hospital, Genoa, Italy, 5Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, Genoa, Italy

 

56014:00 - 16:00

PS32 - DIAMONDS IN AUTOIMMUNITY CONFERENCE ROOM 1

 14:00 - 14:20

SICK BUILDING SYNDROME - NEW INSIGHTS

  T. Tuuminen, Kruunuhaka Medical Center, Helsinki, Finland 14:20 - 14:40

RAB4A-DEPENDENT MECHANISTIC TARGET OF RAPAMYCIN ACTIVATION CONTROLS ORGAN-SPECIFIC DISEASE PATHOGENESIS IN SYSTEMIC LUPUS ERYTHEMATOSUS

 N. Huang, Z. Oaks, T. Winans, B. Wyman, A. Patel, M. Beckford, M. Duarte, J. Lewis, Z.-W. Lai, F. Middleton, L. Morel, M. Haas, K. Banki, A. Perl, SUNY, Syracuse, United States of America

 14:40 - 14:50

EXERCISE PARTICIPATION IN PEOPLE WITH ANTIPHOSPHOLIPID SYNDROME: ASSOCIATIONS WITH EXERCISE SELF-EFFICACY AND ILLNESS PERCEPTION

  K. Hambly, University of Kent, Tunbridge Wells, United Kingdom 14:50 - 15:00

RISK OF CANCER IN MULTIPLE SCLEROSIS (MS): A SYSTEMATIC REVIEW AND META-ANALYSIS.

 M. Ghajarzadeh1, M. Ghajarzadeh2, M. Mohammadifar3, A. Azimi4, A. Mohammadi4, 1tums, tehran, Iran, 2tums, , Iran, 3Zanjan university of medical sciences, `tehran, Iran, 4TUMS, tehran, Iran

 15:00 - 15:10

IMMUNOLOGICAL BEHAVIOR OF THE PATIENT WITH BIOPOLYMERS AND CAUSAL RELATIONSHIP WITH ASIA SYNDROME - PERSONAL EXPERIENCE OF SURGICAL MANAGEMENT WITH OPEN TECHNIQUE

  J.E. Pachon Suarez, NUEVA CLINICA LOS CEDROS, BOGOTA, Colombia 15:10 - 15:20

REINSTALLING IMMUNE REGULATORY TRYPTOPHAN CATABOLISM IN JUVENILE DIABETES VIA INTERLEUKIN 6 RECEPTOR BLOCKADE

  C. Orabona, G. Mondanelli, M.T. Pallotta, E. Orecchini, U. Grohmann, University of Perugia, Perugia, Italy

 15:20 - 15:30

ANTI-DFS70 ANTIBODIES DETECTED AS PART OF A PARTICLE BASED MULTI-ANALYTE TECHNOLOGY SYSTEM AIDS IN THE REFERRAL OF ANA POSITIVE INDIVIDUALS

 A. Seaman1, M. Mahler1, C. Bentow1, K. Malyavantham2, M. Choi3, M. Fritzler3, 1Inova Diagnostics, San Diego, United States of America, 2Inova Diagnostics Inc, San Diego, United States of America, 3University of Calgary, Calgary, Canada

 570

16:00 - 16:30

COFFEE BREAK, EXHIBITION, POSTERS EXHIBITION HALL

56516:30 - 18:30

PS33 - UPDATE ON APS AND SLE ALEXANDRA TRIANTI

 

Moderation: L. Andreoli1, C. Belizna2, T. Atsumi3, 1ASST Spedali Civili, Brescia; University of Brescia, Rheumatology And Clinical Immunology Unit, Brescia, Italy, 2University Hospital Angers and CNRS 6015 INSERM 1083 Unit, Vascular And Coagulation Center, Angers, France, 3 , Japan

 16:30 - 16:45

STROKE: THE MAIN INITIAL AND RECURRENCE CLINICAL MANIFESTATION IN PRIMARY APS PATIENTS OLDER THAN 70 YO IN A SERIES OF 696 PATIENTS

  C. Belizna1, J.O. Latino2, L. Stojanovich3, S. Udry2, N. Stanisavljevic3, A. Djokovic3, P. Saulnier1, J. Alijotas-Reig4, E. Esteve-Valverde5, R. Ferer-Oliveras4, A. Tincani6, L. Andreoli7, F. Regola7, A. Makatsariya8, J. Khizroeva9, V. Bitsadze8, S. Apras Bilgen10, L. Kiliç10, M. Limper11, C. Chighizola12, F. Pregnolato12, M.O. Borghi12, L. Damian13, A. Mekinian14, K. Devreese15, I. Pabinger16, J. Gebhart16, Y. Shoenfeld17, V. Canti18, J.W. Cohen Tervaert19, G. Pires Da Rosa20, F. Said21, M.A. Pistorius22, Á. Carrasco Sayalero23, H. Cohen24, E. Andres25, L. Buffat26, A. Hajjam27, G. Gold28, D. Zekry28, A. Godon29, M. Riviere30, S. Otter31, G. Migliaccio32, F. Bietrix32, A.-C. Fauvel32, R. Cervera33, P.L. Meroni34, J. Belmin35, 1University Hospital Angers and CNRS 6015 INSERM 1083 Unit, Angers, France, 2University Hospital C Durand, Buenos Aires, Argentina, 3University Medical Hospital, Belgrade, Serbia, 4Vall d’Hebron University Hospital, Barcelona, Spain, 5Althaia Healthcare Network of Manresa, Barcelona, Spain, 6 , Italy, 7ASST Spedali Civili, Brescia; University of Brescia, Brescia, Italy, 8 , Russian Federation, 9University Hospital, Moscow, Russian Federation, 10Hacettepe University, Ankara, Turkey, 11University Medical Center Utrecht, Utrecht, Netherlands, 12Auxologico Institute Milan, Milan, Italy, 13County Emergency Hospital Cluj-Napoca, Cluj, Romania, 14Hopital saint-antoine, Paris, France, 15Ghent University Hospital, Gent, Belgium, 16Vienna University Hospital, Vienna, Austria, 17Sheba Medical Center, Tel Aviv, Israel, 18IRCCS San Raffaele Hospital, Milan, Italy, 19 , Canada, 20Sao Joao Hospital, Porto, Porto, Portugal, 21University Hospital La Rabta, Tunis, Tunisia, 22Nantes University Hospital, Nantes, France, 23Hospital Universitario Ramón y Cajal, Madird, Spain, 24niversity College London Hospitals, London, United Kingdom, 25Strasbourg University Hospital, Strasbourg, France, 26Altrabio, Lyon, France, 27Université de Technologie de Belfort-Montbéliard, Belfort, France, 28Geneva University Hospital, Geneva, Switzerland, 29University Hospital Angers, Angers, France, 30Association French lupus and other autoimmune disease, Cuvry, France, 31NVLE, Maastricht, Netherlands, 32EATRIS- ERIC, Amsterdam, Netherlands, 33Hospital Clinic

Barcelona, Barcelona, Spain, 34IRCCS Istituto Auxlogico Italiano, Cusano Milannino - Milan, Italy, 35APHP Charles Foix, Ivry, France

 16:45 - 17:00

CARDIOVASCULAR RISK IN APS: SHOULD I CARE ABOUT?

  M. Tektonidou, Medical School, National and Kapodistrrian University of Athens, Athens, Greece

 17:00 - 17:20

OBSTETRIC ANTIPHOSPHOLIPID SYNDROME IN ECUADOR

  C. Galarza-Maldonado, , Ecuador 17:20 - 17:30

CHANGES IN CELLULAR GLYCOSYLATION AS A KEY FACTOR IN THE IMMUNOPATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS

 

I. Alves1, V. Pinto1, B. Santos-Pereira1, A. Campar2, J.R. Vizcaíno Vázquez3, F. Carneiro4, A. Marinho2, S. Pinho5, 1i3S, University of Porto, Porto, Portugal, 2Hospital de Santo António, Porto, Portugal, 3Hospital Geral de Santo António, Porto, Portugal, 4Hospital de São João, Porto, Portugal, 5University of Porto, Porto, Portugal

 17:30 - 17:40

EXTRA-CRITERIA ANTIPHOSPHOLIPID ANTIBODIES IN PATIENTS WITH SMALL VESSEL BRAIN LESIONS AND CLINICAL MANIFESTATIONS ASSOCIATED WITH ANTIPHOSPHOLIPID SYNDROME.

 

M.Á. Estévez1, A. López-Gómez1, A. Molina-Fuentes1, M.R. Jiménez-León1, M. Montes1, M.J. Picado1, L. Sáez2, S. Sánchez3, L. Pallarés1, M.R. Julià1, 1Hospital Universitario Son Espases, Palma de Mallorca, Spain, 2Hospital Universitario Miguel Servet, Zaragoza, Spain, 3Hospital Fundación Alcorcón, Alcorcón, Spain

 17:40 - 17:50

PREDICTIVE VALUE OF ANTIPHOSPHOLIPID ANTIBODIES IN THE ACUTE PHASE OF DEEP VEIN THROMBOSIS

 

K. Perdan Pirkmajer1, A. Boc2, S. Čučnik1, A. Mavri1, P. Žigon1, E. Podovsovnik3, M. Štalc1, N. Vene1, A. Ambrožič1, 1University Medical Centre Ljubljana, Ljubljana, Slovenia, 2University of Ljubljana; Faculty of Medicine, Ljubljana, Slovenia, 3University of Primorska, Portoroz, Slovenia

 17:50 - 18:00

PREVALENCE OF CONVENTIONAL ANTIPHOSPHOLIPID ANTIBODIES IN A HEALTHY POPULATION

 

V. Salle1, C. Gomila1, D. Fuzellier1, A. Cailly1, A. Brulé2, N. Becquet2, C. Picard1, D. Quignion1, A.-L. Voyer1, Y.-E. Herpe1, F. Rose-Robert1, A. Galmiche1, J. Schmidt1, P. Duhaut1, 1Amiens University Hospital, Amiens, France, 2French Blood Agency-North of France, Amiens, France

 

18:00 - 18:10

VASODILATION OF CUTANEOUS MICROVASCULATURE IS IMPAIRED IN PATIENTS WITH ANTIPHOSPHOLIPID SYNDROME

 E. Blokar1, P. Žigon1, K. Perdan Pirkmajer1, M. Čepar2, Ž. Melik2, A. Ambrožič1, K. Cankar2, 1University Medical Centre Ljubljana, Ljubljana, Slovenia, 2Medical faculty,University of Ljubljana, Ljubljana, Slovenia

 18:10 - 18:20

ANTIPHOSPHOLIPID ANTIBODIES – THE UNKNOWN CAUSALITY OF DYSLIPIDEMIA?

  N. Stoilov, V. Boyadzhieva, Clinic of Rheumatology, University hospital “St. Ivan Rilski”- Sofia, Medical university of Sofia, Sofia, Bulgaria, Sofia, Bulgaria

 18:20 - 18:30

B AND T CELL ENGAGEMENT DURING SYSTEMIC LUPUS ERYTHEMATOSUS DEVELOPMENT

 

A. Tchorbanov1, N. Mihaylova1, S. Bradyanova1, K. Nikolova-Ganeva1, N. Kerekov1, P. Chipinski1, E. Ivanova-Todorova2, D. Kyurkchiev2, M. Herbáth3, J. Prechl3, 1Institute of microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria, 2Medical University of Sofia (Bulgaria), University Hospital “St. Ivan Rilski”, Laboratory of Clinical Immunology, Sofia, Bulgaria, 3Hungarian Academy of Sciences, Budapest, Hungary

 568

16:30 - 18:30

PS34 - TEACHING LESSON ON HOW TO USE THE ICAP BANQUETING

  Moderation: M. Infantino, , Italy 16:30 - 16:55

OVERVIEW OF ICAP IN 2020

  E. Chan, University of Florida, GAINESVILLE, United States of America 16:55 - 17:20

ICAP CLINICAL RELEVANCE CONSENSUS

  J. Damoiseaux, Maastricht University Medical Center, Maastricht, Netherlands 17:20 - 17:45

CONSENSUS ANA REPORTING RECOMMENDATION

  C. Von Muhlen, , Brazil 17:45 - 18:10

HOW CLINICIANS CAN MAKE THE MOST OF ICA

  L. Andrade, Universidade Federal de São Paulo, Escola Paulista de Medicina, Sao Paulo, Brazil

 

18:10 - 18:30

ICAP, A USER’S PERSPECTIVE

  X. Bossuyt, UZ Leuven, Leuven, Belgium 

58016:30 - 18:30

PS35 - RITUXIMAB, B-CELL DEPLETION AND B CELL REGULATORY CELLS

NIKOS SKALKOTAS

  Moderation: Z. Vadasz, , Israel 16:30 - 16:50

SHOOTING B CELL IN AUTOIMMUNE DISEASES WITH RENAL INVOLVEMENT : *RITUXIMAB IN AAV: WHEN, HOW LONG AND BEYOND, *TARGETING B CELL IN LN: NOT ONLY ANTI-CD20

 D. Roccatello, SCU Nephrology and Dialysis & Center of Research of Immunopathology and Rare Diseases - Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, Turin, Italy

 16:50 - 17:10

RITUXIMAB BIOSIMILARS

  M. Scheinberg, Autoimmune Disease Center, Sao Paulo, Brazil 17:10 - 17:20

USE OF RITUXIMAB AND MEPOLIZUMAB FOR EGPA

  D. Albert, A. Gifford, Geisel School of Medicine at Dartmouth, Lebanon, United States of America

 17:20 - 17:30

ENTEROVIRUS INFECTION AS A RARE BUT LIFE-THREATENING COMPLICATION AFTER THERAPY WITH ANTI-CD20-ANTIBODY IN PATIENT WITH MALIGNANT LYMPHOMA AND EOSINOPHILIC FASCIITIS

  M. Geroldinger-Simic, N. Sepp, Ordenklinikum Linz Elisabethinen, Linz, Austria 17:30 - 17:40

REGULATORY B-CELLS IN PATIENTS WITH GRANULOMATOSIS WITH POLYANGIITIS ARE REDUCED IN THE BLOOD AND FAIL TO REGULATE T CELL IFN-Y PRODUCTION

  D. Appelgren1, S. Puli2, J. Ernerudh1, P. Eriksson1, M. Segelmark2, 1Linköping University, Linköping, Sweden, 2Lund University, Lund, Sweden

 17:40 - 17:50

MODIFIED B CELL ACTIVATION IN NKX2.3 KNOCK-OUT MICE: A POSSIBLE EXPLANATION FOR AMELIORATED AUTOIMMUNE ARTHRITIS

  E. Khanfar, E. Gajdocsi, K. Olasz, R. Kugyelka, Z. Kellermayer, F. Gabris, P. Balogh, T. Berki, F. Boldizsar, University of Pecs, Pecs, Hungary

 17:50 - 18:00

INCREASED AGE-RELATED B-CELLS (ABCS) IN PATIENTS WITH APLASTIC ANEMIA

  E. Solomou1, C. Salamaliki1, F. Pouliasi1, C. Gogos1, S. Liossis2, 1UNIVERSITY OF PATRAS MEDICAL SCHOOL, PATRAS, Greece, 2 , Greece

 18:00 - 18:10

UNFOLDED PROTEIN RESPONSE AND SYSTEMIC LUPUS ERYTHEMATOSUS: AN INSIGHT INTO GADD34 OVEREXPRESSION IN B CELLS OF LUPUS PATIENTS

 

L. Joly1, C. Dumestre-Perard2, F. Sarrot-Reynauld1, L. Bouillet1, S. Béatrix1, F. Martinez1, J.-L. Quesada1, J. Labarère1, F. Defendi1, P. Audoin1, J.-Y. Cesbron3, G. Clavarino3, 1Grenoble Alpes University Hospital, Grenoble, France, 2Grenoble Alpes University Hospital, Grenoble Cedex 9, France, 3Grenoble Alpes University Hospital, Grenoble Cedex, France

 18:10 - 18:20

EFFICACY AND SAFETY OF RITUXIMAB IN TREATING PATIENTS WITH MULTIPLE SCLEROSIS (MS): A SYSTEMATIC REVIEW AND META-ANALYSIS.

 M. Ghajarzadeh1, A. Azimi2, M.A. Sahraian3, Z. Valizadeh3, M. Mohammadifar4, 1tums, , Iran, 2TUMS, tehran, Iran, 3tums, `tehran, Iran, 4Zanjan university of medical sciences, `tehran, Iran

 610

16:30 - 18:30

PS36 - EXPERIMENTAL AUTOIMMUNE MODELS MC3

  Moderation: E. Schmidt1, J.M. Anaya2, 1 Lübeck, Germany, 2 , Colombia 16:30 - 16:50

PRE-CLINICAL RESEARCH IN VIVO: PROS AND CRONS OF THE C3H/HEJ VERSUS HUMANIZED MOUSE MODE

  A. Gilhar, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology,, Haifa, Israel

 16:50 - 17:10

HASHIMOTO’S ENCEPHALOPATHY ANTI-THYROID PEROXIDASE IGG INDUCES DEPRESSION IN NAÏVE MICE: RESULTS OF A PRELIMINARY STUDY

 

T. Drori1, E. Shavit Stein2, P. Sobolevskaia3, L. Churilov4, T. Fedotkina5, Y. Ostrinski6, G. Halpert2, O. Shovman6, J. Chapman7, M. Blank6, Y. Shoenfeld8, H. Amital6, 1Sheba medical center, Ramat Gan, Israel, 2Sheba Medical Center, Ramat Gan, Israel, 3Saint-Petersburg State University, Saint-Petersburg, Russian Federation, 4Laboratory of the Mosaic of Autoimmunity, Saint-Petersburg, Russian Federation, 5Saint Petersburg State University, Saint-Petersburg, Russian Federation, 6Sheba Medical Center, Tel-Hashomer, Israel, 7Sheba Medical Center, Israel, Ramat Gan, Israel, 8Sheba Medical Center, Tel Aviv, Israel

 

17:10 - 17:30

EXPERIMENTAL MODELS IN PEMPHIGUS

  E. Schmidt, University of Lübeck, Lübeck, Germany 17:30 - 17:40

A NEW MURINE MODEL OF VITILIGO-LIKE DEPIGMENTATION INDUCED BY MIA (MELANOMA INHIBITORY ACTIVITY) PROTEIN: A NEW INSIGHT IN THE PATHOGENETIC HYPOTHESES OF VITILIGO.

 

R. Luisetto1, M. Bordignon2, M. Fedrigo3, A. Scanu1, C. Castellani4, A. Angelini4, M. Alaibac2, 1University of Padova, Padova, Italy, 2Dermatology Unit, University of Padova, Padova, Italy, 3Azienda Ospedaliera Padova, Padova, Italy, 4Pathology Unit, University of Padova, Padova, Italy

 17:40 - 17:50

VISUALIZATION OF KINETICS AND DYNAMICS OF DENDRITIC CELLS IN EXPERIMENTAL AUTOIMMUNE EPIDERMOLYSIS BULLOSA ACQUISITA

  R. Akbarzadeh1, P. König2, 1Institute of Anatomy, University of Lübeck, Lübeck, Germany, 2Institute of Anatomy, Lübeck, Germany

 17:50 - 18:00

PROGRESSION OF AUTOIMMUNITY AND FAILURE OF REPRODUCTION – LESSONS FROM THE ANIMAL MODELS

 A. Tchorbanov1, G. Boneva1, K. Nikolova-Ganeva1, N. Mihaylova1, S. Delimitreva2, J. Prechl3, 1Institute of microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria, 2Medical University of Sofia, Sofia, Bulgaria, 3Hungarian Academy of Sciences, Budapest, Hungary

 18:00 - 18:10

STUDY OF THE CONCENTRATION OF SMALL FRACTION IMMUNE COMPLEXES IN THE TISSUES OF EXPERIMENTAL WHITE MICE UNDER CONDITIONS OF IMMOBILIZATION STRESS

 D. Labunskiy1, S. Kiryukhina2, V. Podsevatkin2, F. Kiryukhin2, N. Kurgaev2, N. Kolmykova2, 1 Saransk, Russian Federation, 2Ogarev Mordovia State University, Saransk, Russian Federation

 18:10 - 18:20

IGG FROM PATIENTS WITH CHRONIC FATIGUE SYNDROME AND ANTI AUTONOMIC ANTIBODIES BIND SPECIFIC STRUCTURES IN THE SKIN

 T. Drori1, G. Halpert2, M. Blank3, D. Keren2, A. Dori2, Y. Shoenfeld4, 1Sheba medical center, Ramat Gan, Israel, 2Sheba Medical Center, Ramat Gan, Israel, 3Sheba Medical Center, Tel-Hashomer, Israel, 4Sheba Medical Center, Tel Aviv, Israel

 18:20 - 18:30

LOW-DOSE INTERLEUKIN-2: BIOLOGY AND THERAPEUTIC PROSPECTS IN RHEUMATOID ARTHRITIS

 R. Wu1, N. Li1, X. Zhao1, T. Ding1, H. Xue1, C. Gao2, X. Li1, C. Wang1, 1the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China, Taiyuan, China, 2Brigham and Women’s Hospital, Harvard Medical School,, Boston, United States of America

 620

16:30 - 18:30

PS37 -IVIG AND NATURAL AUTOANTIBODIES MC2

  Moderation: L. Mouthon1, M.G. Danieli2, 1 , France, 2Università Politecnica della Marche-Ospedali Riuniti, Scienze Cliniche E Molecolari, Ancona, Italy

 16:30 - 16:50

FROM BEHRING TO BRUTON AND BEYOND: THE STORY OF IVIG

  S. Kaveri., cnrs, Paris, France 16:50 - 17:05

IVIG THERAPY IN SLE AND OTHER AUTOIMMUNE DISEASES

  G. Zandman-Goddard, wolfson, holon, Israel 17:05 - 17:20

IVIG IN SECONDARY IMMUNE DEFICIENCIES

  L. Mouthon, , France 17:20 - 17:30

INTRAVENOUS IMMUNOGLOBULIN (IVIG) FOR INFLAMMATORY MYOSITIS: OUR EXPERIENCE IN A TERTIARY MEDICAL CENTER

 M. Ohad1, A. Shemer2, I. Lavie1, D. Ozeri2, Y. Shoenfeld3, S. Kivity2, 1Tel Aviv University, Tel Aviv, Israel, 2Sheba Medical Center, Tel-Hashomer, Israel, 3Sheba Medical Center, Tel Aviv, Israel

 17:30 - 17:40

ANTI-NEURONAL ANTIBODIES WITHIN THE IVIG PREPARATIONS: IMPORTANCE IN CLINICAL PRACTICE

  H. Alexopoulos1, M. Dimitriadou2, S. Akrivou2, E. Gola2, M. Dalakas2, 1University of Athens, Athens, Greece, 2National and Kapodistrian University of Athens, Athens, Greece

 17:40 - 17:50

LONG-TERM EFFICACY AND TOLERABILITY OF SUBCUTANEOUS IMMUNOGLOBULIN (GAMMANORM) IN INFLAMMATORY MYOPATHIES: A 5-YEAR FOLLOW-UP IN 30 PATIENTS

 

P. Cherin1, C. De Jaeger2, C. Belizna3, M. Pha4, T. Chazal4, Z. Amoura4, 1Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Assistance Publique – Hôpitaux de Paris (AP-HP), Paris, Cedex 13, France, 2Institut De Jaeger, Paris, France, 3University Hospital Angers and CNRS 6015 INSERM 1083 Unit, Angers, France, 4Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Assistance Publique – Hôpitaux de Paris (AP-HP), Paris, France

 17:50 - 18:00

HLA-I IGG ANTIBODIES IN THEMOROCCAN IVIG CORRESPONDED WITH SEVERAL HIGH FREQUENCIES HLA-I ALLELES IN SAME POPULATION

  F. Elhilali1, H. Elhilali2, 1Hospital Mohamed V, Meknes, Morocco, 2hopital Mohamed V, Meknes, Morocco

 18:00 - 18:10

IVIG THERAPY FOR SLE AND OTHER AUTOIMMUNE DISEASES

 M. Tocut1, O. Shovman2, Y. Haviv3, G. Zandman-Goddard4, 1Edith Wolfson Medical Center, Holon, Israel, 2Sheba Medical Center, Tel-Hashomer, Israel, 3Sheba Medical Center, Ramat Gan, Israel, 4wolfson, holon, Israel

 18:10 - 18:20

ROLE OF INTRAVENOUS IMMUNOGLOBULINS IN THE TREATMENT OF SMALL FIBER NEUROPATHY

  N. Basantsova, Saint-Petersburg State University, Saint-Petersburg, Russian Federation 

63016:30 - 18:30

PS38 -VASCULITIS - WHAT'S NEW? KOKKALI

 Moderation: C. Salvarani1, J.W. Cohen Tervaert2, O. Shovman3, 1Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reumatologia, Reggio Emilia, Italy, 2 , Canada, 3Sheba Tel-Hashomer, Zabludowicz Center For Autoimmune Diseases, Tel-Hashomer, Israel

 16:30 - 16:50

WHAT IS NEW IN THE THERAPY OF SYSTEMIC VASCULITIDES IN 2020?

  R. Luqmani, University of Oxford, Oxford, United Kingdom 16:50 - 17:10

TREATMENT OF LARGE VESSEL VASCULITIS

  C. Salvarani, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy 17:10 - 17:20

PROTECTIVE EFFECTS OF EXTRACELLULAR VESICLES DERIVED FROM ENDOTHELIAL PROGENITOR CELLS IN ANCA-ASSOCIATED VASCULITIS

 V. Cantaluppi1, G. Merlotti1, S. Dellepiane1, D. Medica1, M. Quaglia2, G. Camussi3, 1Center for Traslational Research on Autoimmune and Allergic Disea se—CAAD, University of Eastern Piedmont, Novara, Italy, 2 TORINO, Italy, 3University of Torino, Torino, Italy

 17:20 - 17:30

GIANT CELLS ARTERITIS: TOCILIZUMAB DISCONTINUATION AFTER 52 WEEKS OF TREATMENT IS A FEASIBLE OPTION? A RETROSPECTIVE MONOCENTRIC STUDY ON LONG-TERM TREATMENT IN 32 PATIENTS

 

F. Regola1, E. Cerudelli2, G. Bosio2, A. Tincani3, F. Franceschini4, P. Toniati5, 1ASST Spedali Civili, Brescia; University of Brescia, Brescia, Italy, 2ASST Spedali Civili di Brescia, Brescia, Italy, 3 , Italy, 4ASST Spedali Civili, Brescia, Italy, 5ASST Spedali Civili and University of Brescia, Brescia, Italy

 17:30 - 17:40

ALLERGIC PROFILE AND ALLERGEN-SPECIFIC IMMUNOTHERAPY IN EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS (EGPA): A SINGLE CENTER OBSERVATIONAL STUDY.

  L. Moroni, A. Cariddi, E. Della Torre, T. Germanò, G. Ramirez, E. Bozzolo, M.-R. Yacoub, L. Dagna, San Raffaele Scientific Institute, Milano, Italy

 17:40 - 17:50

TAKAYASU ARTERITIS AND SACROILIITIS: A CASE CONTROL STUDY IN 28 PATIENTS OF A SINGLE ITALIAN CENTER

 

F. Regola1, G. Bosio2, E. Cerudelli2, A. Tincani3, F. Franceschini4, P. Toniati5, 1ASST Spedali Civili, Brescia; University of Brescia, Brescia, Italy, 2ASST Spedali Civili di Brescia, Brescia, Italy, 3 , Italy, 4ASST Spedali Civili, Brescia, Italy, 5ASST Spedali Civili and University of Brescia, Brescia, Italy

 17:50 - 18:00

NEUTROPHIL ELASTASE INHIBITION IS PROTECTIVE IN EXPERIMENTAL MYELOPEROXIDASE ANTI NEUTROPHIL CYTOPLASMIC ANTIBODY VASCULITIS

  K.M. O'Sullivan, P.-Y. Gan, S. Holdsworth, Monash University, Melbourne, Australia 18:00 - 18:10

FROM ACTIVE TO NON-ACTIVE: EMPHASIS ON LONGITUDINAL NEUTROPHIL PROFILING IN PATIENTS WITH GIANT CELL ARTERITIS ON CORTICOSTEROID THERAPY IN COMBINATION WITH LEFLUNOMIDE

 

T. Kuret1, K. Lakota2, G. Thallinger3, B. Burja1, P. Žigon1, A. Kopitar4, S. Čučnik1, M. Tomšič1, S. Sodin-Semrl1, A. Hočevar1, 1University Medical Centre Ljubljana, Ljubljana, Slovenia, 2University of Primorska, Koper, Slovenia, 3Graz University of Technology, Graz, Austria, 4University of Ljubljana, Ljubljana, Slovenia

 18:10 - 18:20

MORTALITY AMONG PATIENTS WITH GIANT-CELL ARTERITIS: A LARGE-SCALE POPULATION-BASED COHORT STUDY

 

N. Ben Shabat1, S. Tiosano2, O. Shovman3, D. Comaneshter4, Y. Shoenfeld5, A. Cohen6, H. Amital3, 1Chaim Sheba Medical Center at Tel HaShomer, Tel hashomer, Israel, 2Sheba medical center, Ramat Gan, Israel, 3Sheba Medical Center, Tel-Hashomer, Israel, 4Clalit Health Services, tel aviv, Israel, 5Sheba Medical Center, Tel Aviv, Israel, 6Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel

 18:20 - 18:30

LARGE VESSEL VASCULITIS: PET/CT RESULTS FROM A LARGE COHORT

  J. Ben Shimol1, Y. Shoenfeld2, T. Davidson2, 1E. Wolfson Medical Center, Holon, Israel, 2Sheba Medical Center, Tel Aviv, Israel

 635

16:30 - 18:30

PS39 - MYOSITIS AND WHAT’S NEW IN DIAGNOSTIC OF AUTOIMMUNE DISEASES?

CONFERENCE ROOM 1

  Moderation: T. Matthias1, B. Gilburd2, 1AESKU.GROUP, Ceo, Wendelsheim, Germany, 2 Ramat Gan, Israel

 16:30 - 16:40

COMPARISON OF AUTOANTIBODY SPECIFICITIES TESTED BY A LINE BLOT ASSAY AND IMMUNOPRECIPITATION-BASED ALGORITHM IN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES

  F. Espinosa-Ortega, Karolinska Institute, Stockholm, Sweden 16:40 - 16:50

GLOBAL META ANALYSIS OF AUTOANTIBODY REPERTOIRES IN HEALTH AND DISEASE

 

R. Sjöberg1, A. Zandian2, M. Andersson3, C. Hellström3, J. Olofsson3, A. Jernbom Falk4, E. Pin5, A. Månberg3, P. Nilsson6, 1KTH - Royal Institute of Technology, Solna, Sweden, 2KTH Royal Institute of Technology & SciLifeLab, Stockholm, Sweden, 3Div. of Affinity Proteomics, Dept. of Protein Science, KTH Royal Institute of Technology, Stockholm, Sweden, 4KTH/SciLifeLab, Solna, Sweden, 5KTH - Scilifelab, Solna, Sweden, 6KTH - Scilifelab, Stockholm, Sweden

 16:50 - 17:00

COMMON AND SPECIFIC BIOMARKERS IN AUTOIMMUNE RHEUMATIC DISEASES

 

Y. Pacheco1, M. Rojas2, Y. Acosta-Ampudia1, D. Monsalve1, R. Mantilla1, C.E. Toro Gutierrez3, G.J. Tobón4, J.-M. Anaya1, C. Ramírez-Santana1, 1School of Medicine and Health Sciences, Bogotá D.C, Colombia, 2Universidad del Rosario, Bogotá D.C, Colombia, 3Centro de Referencia en Osteoporosis & Reumatología, Cali, Colombia, 4Fundación Valle del Lili, Universidad Icesi, Cali, Colombia

 17:00 - 17:10

ALGORITHM FOR ANTINUCLEAR ANTIBODIES IN SUBJECTS WITH CLINICAL SUSPICION OF AUTOIMMUNE DISEASE

 

L. Naranjo1, O. Shovman2, D. Pérez3, M. Infantino4, O. Cabrera-Marante5, F. Lozano Morillo6, B. Gilburd7, M. Manfredi8, M. Serrano9, L. Morillas6, Y. Shoenfeld10, A. Serrano5, 1Hospital Universitario 12 de Octubre, MADRID, Spain, 2Sheba Medical Center, Tel-Hashomer, Israel, 3Hospital Universitario 12 de Octubre, Madrid, Spain, 4Ospedale San Giovanni di Dio, Azienda Usl Toscana Centro, Firenze, Italy, 5Hospital doce de octubre, madrid, Spain, 6Hospital Universitario 12 de Octubre, madrid, Spain, 7Sheba Medical Center, Ramat Gan, Israel, 8San Giovanni di Dio Hospital, Azienda USL Toscana Centro, Florence, Italy, 9Hospital Clinico San Carlos, madrid, Spain, 10Sheba Medical Center, Tel Aviv, Israel

 17:10 - 17:20

DIAGNOSTIC VALUE OF A COMMERCIAL LINE BLOT ASSAY FOR ONCONEURAL ANTIBODY TESTING

  R. Ruiz-García1, E. Martínez-Hernández2, M.A. Romera1, M.C. Antón1, R. Couso1, A.

Saiz2, J. Dalmau2, F. Graus2, 1Hospital Clinic, BARCELONA, Spain, 2Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), BARCELONA, Spain

 17:20 - 17:30

DIAGNOSTIC PERFORMANCE OF ANTI-CYCLIC CITRULLINATED PEPTIDE (CCP) 2 AND CCP3.1 ASSAYS IN EARLY RHEUMATOID ARTHRITIS

  D. Sieghart1, C. Konrad2, S. Swiniarski2, H. Haslacher1, D. Aletaha1, G. Steiner1, 1Medical University of Vienna, Vienna, Austria, 2Thermo Fisher Scientific, Freiburg, Germany

 17:30 - 17:40

THE ALTERED METABOLISM PROFILE IN PATHOGENESIS OF IDIOPATHIC INFLAMMATORY MYOPATHIES

  D. Liu, X. Zuo, H. Luo, H. Zhu, Xiangya Hospital, Central South University, changsha, China 17:40 - 17:50

REAL WORLD EXPERIENCE OF CORRELATION BETWEEN AUTOIMMUNE SEROLOGY AND CLINICAL FINDINGS IN IDIOPATHIC INFLAMMATORY MYOSITIS

 

T. Manetta1, S.G. Foddai2, T.E. Mongini1, E. Menegatti3, G. Mengozzi4, 1AOU Città della Salute e della Scienza, Turin, Italy, 2University of Turin, Turin, Italy, 3School of Specialization of Clinical Pathology, Turin, Italy, 4AOU Città della Salute e della Scienza di Torino, Turin, Italy

 17:50 - 18:00

ANTI-RNP ANTIBODIES DELINEATE A SUBGROUP OF MYOSITIS : A SYSTEMATIC RETROSPECTIVE STUDY ON 46 PATIENTS.

 

N. Wesner1, A. Uruha2, S. Suzuki3, K. Mariampillai1, B. Granger4, N. Champtiaux1, A. Rigolet1, Y. Schoindre5, S. Lejeune6, P. Guillaume-Jugnot1, M. Vautier1, B. Hervier1, A. Simon1, F. Granier7, L. Gallay8, I. Nishino9, O. Benveniste1, Y. Allenbach1, 1Pitie Salpetriere Hospital, Paris, France, 2Tokyo Metropolitan Neurological Hospital, Tokyo, Japan, 3Keio University School of Medicine, Tokyo, Japan, 4Pitié Salpétrière Hospital, Paris, France, 5Foch Hospital, Suresnes, France, 6Avicennes Hospital, Bobigny, France, 7Centre Hospitalier François Quesnay, Mantes la Jolie, France, 8Hospices Civils de Lyon, Lyon, France, 9National Institute of Neuroscience and Department of Genome Medicine Development, Tokyo, Japan

 18:00 - 18:10

PREVALENCE OF ANTI-CN1A AUTOANTIBODIES IN A FRENCH COHORT OF PATIENTS WITH INCLUSION BODY MYOSITIS.

 

D. Goncalves1, T. Vincent2, L. Gallay3, N. Streichenberger4, R. Juntas-Morales5, S. Dubucquoi6, D. Lakomy6, C. Johanet6, F. Fortenfant7, R.-L. Humbel6, P. Chretien6, B. Nespola6, S. Hue6, F. Coutant1, N. Fabien8, 1Hospices Civils de Lyon - Hôpital Lyon Sud, Pierre-Bénite, France, 2Montpellier Univesity Hospital, Montpellier, France, 3Hospices Civils de Lyon, Lyon, France, 4Hospices Civils de Lyon - Groupement Hospitalier Est, Bron, France, 5Montpellier University Hospital, Montpellier, France, 6Groupe d'Etude de l'Auto-Immunité, Angers, France, 7CHU TOULOUSE, Toulouse, France, 8Hospices Civils de Lyon, CHLS, Pierre-Bénite, France

 18:10 - 18:20

CLINICAL IMPLICATIONS OF ASSOCIATED AND SPECIFIC AUTOANTIBODIES IN IDIOPATHIC INFLAMMATORY MYOPATHIES.

  A. Campar, Hospital de Santo António, Porto, Portugal

 Tuesday 01-06-2021

65008:00 - 10:00

PL03 PLENARY SESSION IN MEMORY OF JORGE MARTINS

ALEXANDRA TRIANTI

 

Moderation: Y. Shoenfeld1, C. Vasconcelos2, M. Scheinberg3, T. Koike4, 1Sheba Medical Center, Zabludowicz Center For Autoimmune Diseases, Tel Aviv, Israel, 2UMIB-ICBAS-UPorto, Autoimmunity And Neuroscience, Porto, Portugal, 3Autoimmune Disease Center, Internal Medicine, Sao Paulo, Brazil, 4Hokkaido Medical Center for Rheumatic Diseases, Supreme Advisor, Sapporo, Japan

 08:00 - 08:30

FROM BASIC SCIENCE TO THERAPEUTICS: THE STORY OF IL-2

  A. Abbas, University of California San Francisco, San Francisco, United States of America 08:30 - 09:00

REVERSING AUTOIMMUNITY--COMBINATION THERAPY WITH RITUXIMAB AND IVIG

  R. Ahmed, , United States of America 09:00 - 09:30

FUNCTIONAL GENETICS IN SYSTEMIC LUPUS ERYTHEMATOSUS

  T. Niewold   , , United States of America 09:30 - 10:00

BONE AND HEART: IS AUTOIMMUNITY A LINK?

  Z. Szekanecz, , Hungary 

66010:00 - 10:30

COFFEE BREAK, EXHIBITION, POSTERS EXHIBITION HALL

67010:30 - 12:30

PS40 - NOVELTIES IN VASCULITIDES ALEXANDRA TRIANTI

  Moderation: A. Doria, R. Perricone, , Italy 10:30 - 10:50

SYSTEMIC VASCULITIS: NEW TREATMENT APPROACHES

  D. D'Cruz, , United Kingdom 10:50 - 11:10

INTERNATIONAL CONSENSUS ON ANCA TESTING BEYOND SYSTEMIC VASCULITIS

 

J.W. Cohen Tervaert1, S. Moiseev2, Y. Arimura3, D. Bogdanos4, E. Csernok5, J. Damoiseaux6, I. Dotan7, M. Ferrante8, L.F. Flores-Suarez9, M. Fritzler10, P. Invernizzi11, D. Jayne12, C. Jennette13, M. Little14, S. Mcadoo15, P. Novikov16, C. Pusey15, A. Radice17, A. Salama18, J. Savige19, M. Segelmark20, Y. Shoenfeld21, R. Sinico22, M.-J. Sousa23, U. Specks24, B. Terrier25, A. Tzioufas26, S. Vermeire8, M.-H. Zhao27, X. Bossuyt28, 1 , Canada, 2university of alberta, edmonton, Canada, 3kyorin university, tokyo, Japan, 4University of Thessaly, Larissa, Greece, 5university of tubingen, kirchheim, Germany, 6Maastricht University Medical Center, Maastricht, Netherlands, 7tel aviv university, tel aviv, Israel, 8university hospitals leuven, leuven, Belgium, 9instituto nacional de enfermedades respiratorias, mexico city, Mexico, 10University of Calgary, Calgary, Canada, 11university of milano, milan, Italy, 12University of Cambridge, Cambridge, United Kingdom, 13unc kidney center, chapel hill, United States of America, 14trinity health kidney centre, dublin, Ireland, 15imperial college, london, United Kingdom, 16Sechenov First Moscow State Medical University, Moscow, Russian Federation, 17san carlo borromeo hospital, milan, Italy, 18university college london, london, United Kingdom, 19university of melbourne, melbourne, Australia, 20Lund University, Lund, Sweden, 21Sheba Medical Center, Tel Aviv, Israel, 22universita degli studi di milano, monza, Italy, 23centro de medicina laboratorial germano de sousa, lisbon, Portugal, 24mayo clinic, rochester, United States of America, 25hopital cochin, paris, France, 26NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS, ATHENS, Greece, 27peking university, bejing, China, 28UZ Leuven, Leuven, Belgium

 11:10 - 11:20

THE ASSOCIATION BETWEEN GIANT CELL ARTERITIS AND HEMATOLOGIC MALIGNANCIES

  H. Amital, Sheba Medical Center, Tel-Hashomer, Israel 11:20 - 11:30

CLINICAL, HISTO-PATHOLOGICAL AND IMMUNOFLUORESCENCE STUDY OF CUTANEOUS SMALL VESSEL VASCULITIS IN A TERTIARY CARE HOSPITAL

  A. Inamadar, BLDE Deemed University , Bijapur, India 11:30 - 11:40

EFFICACY AND SAFETY OF TNFA ANTAGONISTS AND TOCILIZUMAB IN TAKAYASU ARTERITIS: MULTICENTER EUROPEAN RETROSPECTIVE STUDY OF 203 PATIENTS.

  A. Mekinian1, D. Saadoun2, 1Hopital saint-antoine, Paris, France, 2sain antoine, paris, France 11:40 - 11:50

CLINICAL ASSOCIATIONS OF RENAL INVOLVEMENT IN ANCA-ASSOCIATED VASCULITIS

  A. Kronbichler1, J.I. Shin2, K.H. Lee2, D. Nakagomi3, L. Quintana4, M. Busch5, A. Craven6, R. Luqmani6, P. Merkel7, G. Mayer1, D. Jayne8, R. Watts9, 1Medical University Innsbruck, Innsbruck, Austria, 2Yonsei University College of Medicine, Seoul, Korea, Republic of, 3University of Yamanashi, Yamanashi, Japan, 4University of Barcelona, Barcelona,

Spain, 5University Hospital Jena, Jena, Germany, 6University of Oxford, Oxford, United Kingdom, 7University of Pennsylvania, Philadelphia, United States of America, 8University of Cambridge, Cambridge, United Kingdom, 9University of East Anglia, Norwich, United Kingdom

 11:50 - 12:00

BIRMINGHAM VASCULITIS ACTIVITY SCORE AND DISEASE EXTENT INDEX AS A DISEASE ASSESSMENT TOOLS IN CRYOGLOBULINEMIC VASCULITIS

  A. Plavsic1, S. Andrejevic1, B. Bonaci Nikolic2, S. Arandjelovic1, 1Clinical Centre of Serbia, Belgrade, Serbia, 2University of Belgrade, Belgrade, Serbia

 12:00 - 12:10

VARIABILITY OF CLINICAL CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH ANCA-ASSOCIATED VASCULITIDES IN A LATIN-AMERICAN HOSPITAL

 

E. Santacruz-Sandoval1, J. López-Bonilla2, L.A. Guevara-Calderón2, C. Aragon3, I. Nieto-Aristizábal1, I. Posso-Osorio1, V. Santos4, C. Cañas2, G.J. Tobón1, D. Aguirre-Valencia2, 1Fundación Valle del Lili, Universidad Icesi, Cali, Colombia, 2Fundación Valle del Lili, Cali, Colombia, 3Universidad Icesi, Cali, Colombia, 4Facultad de Medicina, Universidad Icesi, Cali, Colombia

 12:10 - 12:20

RED CELL DISTRIBUTION WIDTH IS A POTENTIAL PREDICTOR OF EARLY RELAPSE IN POLYMYALGIA RHEUMATICA

 

D. Soddu1, D. Sola2, M. Bellan3, E. Boin3, M. Cittone3, E. Zecca3, E. Matino3, R. Pedrazzoli3, M. Pirisi2, P.P. Sainaghi2, 1University of Piemonte Orientale Amedeo Avogadro, Novara, Italy, 2Maggiore della Carità” Hospital, Novara, Italy, 3University of Piemonte Orientale UPO, Novara, Italy

 12:20 - 12:30

THE PATHOGENIC ROLE OF CIRCULATING HASHIMOTO'S THYROIDITIS-DERIVED TPO POSITIVE IGG ON FETAL DEVELOPMENT IN NAÏVE MICE: RESULTS OF PRELIMINARY STUDY

 

E. Borodina1, I. Katz2, A. Antonelli3, A.M. Gzgzyan1, L.K.H. Dzhemlikhanova1, Y. Ostriski1, D. Niauri1, G. Halpert4, J. Khizroeva5, V. Bitsadze6, A. Makatsariya6, A. Tincani7, C. Nalli8, L. Churilov9, M. Blank10, Y. Shoenfeld11, H. Amital10, 1Saint Petersburg State University, The Laboratory of the Mosaic of Autoimmunity, Saint Petersburg, Russian Federation, 2Tel Aviv University, Tel Aviv, Israel, 3University of Pisa, Pisa, Italy, 4Sheba Medical Center, Ramat Gan, Israel, 5University Hospital, Moscow, Russian Federation, 6 , Russian Federation, 7 , Italy, 8ASST Spedali Civili, Brescia, Brescia, Italy, 9Laboratory of the Mosaic of Autoimmunity, Saint-Petersburg, Russian Federation, 10Sheba Medical Center, Tel-Hashomer, Israel, 11Sheba Medical Center, Tel Aviv, Israel

 680

10:30 -

PS41 - GENETICS AND EPIGENETICS IN BANQUETING

12:30 AUTOIMMUNITY  Moderation: S. Jacobsen, , Denmark 10:30 - 10:50

GENE-ENVIRONMENT INTERACTIONS – RISK AND PHENOTYPES OF SYSTEMIC AUTOIMMUNITY

  S. Jacobsen, , Denmark 10:50 - 11:00

IRF5 GENETIC RISK VARIANTS DRIVE MYELOID-SPECIFIC IRF5 HYPER-ACTIVATION AND PRE-SYMPTOMATIC SLE

 D. Li1, B. Matta1, S. Song1, V. Neslon1, K. Diggins2, K. Simpfendorfer1, P. Gregersen1, P. Linsley2, B.J. Barnes1, 1Feinstein Institute for Medical Research, Manhasset, United States of America, 2Benaroya Research Institute at Virginia Mason, Seattle, United States of America

 11:00 - 11:10

EXPRESSION OF HUMAN REG IV GENE IN INFLAMMATORY BOWEL DISEASES AND ITS POSSIBLE MECHANISM

  S. Takasawa, C. Tsuchida, S. Sakuramoto-Tsuchida, T. Uchiyama, M. Makino, A. Yamauchi, A. Itaya-Hironaka, Nara Medical University, Kashihara, Japan

 11:10 - 11:20

UNDERSTANDING THE IMMUNOPATHOGENESIS OF AUTOIMMUNE DISEASES BY ANIMAL STUDIES USING GENE MODULATION: A COMPREHENSIVE REVIEW

  K.H. Lee1, A. Kronbichler2, J.I. Shin1, 1Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Medical University Innsbruck, Innsbruck, Austria

 11:20 - 11:30

A SPECTRUM OF EARLY ONSET AUTOIMMUNITY CAUSED BY NOVEL MUTATIONS IN LRBA GENE FROM 3 DIFFERENT INDIAN FAMILIES

  A. Jindal, A. Rawat, R. Tyagi, A. Banday, D. Suri, G. Anjani, S. Singh, Postgraduate Institute of Medical Education and Research, Chandigarh, India

 11:30 - 11:40

THE RELATIONSHIPS BETWEEN TOLL-LIKE RECEPTOR GENES POLYMORPHISM AND ATHEROGENIC LIPID DISORDERS

 

M. Muzalevskaya1, V. Miroshnikova2, S. Urazgildeeva3, N. Razgildina4, I. Pobozheva5, V. Gurevich3, 1Sokolov's hospital, St. Petersburg, Russian Federation, 2Saint-Petersburg state Pavlov's medical university, saint-petersburg, Russian Federation, 3Saint-Petersburg state university, saint-petersburg, Russian Federation, 4Saint-Peterburg Pavlov medical university, St. Petersburg, Russian Federation, 5St-Petersburg Pavlov's state medical university, St. Petersburg, Russian Federation

 11:40 - 11:50

THE OPPOSITE EFFECT OF HLA-DRB1 IN TUBERCULOSIS AND SARCOIDOSIS

 A. Malkova1, A. Starshinova2, Y. Zinchenko3, N. Basantsova2, Y. Shoenfeld4, 1 , Russian Federation, 2St.Petersburg State University, St.Petersburg, Russian Federation, 3SPSU, Saint Petersburg, Russian Federation, 4Sheba Medical Center, Tel Aviv, Israel

 11:50 - 12:00

MULTIPLE AUTOIMMUNE DISEASES IN A FAMILY WITH A NOVEL CTLA4 GENE VARIANT

 A. Llarens1, I. Moreira1, L. Regairaz1, G. Seminario1, M. Gaillard1, M. Caldirola2, L. Bezrodnik1, 1Centro de Inmunología Clínica, Ciudad de Buenos Aires, Argentina, 2Hospital de Niños Ricardo Gutierrez, Ciudad de Buenos Aires, Argentina

 12:00 - 12:10

KIDNEY TERTIARY LYMPHOID STRUCTURES IN LUPUS NEPHRITIS DEVELOP INTO LARGE INTERCONNECTED NETWORKS AND RESEMBLES LYMPH NODES IN GENE SIGNATURE.

 

E. Dorraji1, P. Kanapathippillai1, A.-M. Hovd1, M. Stenersrød1, K. Horvei1, A. Ursvik1, S. Figenschau1, D. Thiyagarajan1, C. Fenton2, H. Pedersen1, K. Fenton3, 1UiT the arctic university of Norway, Tromsoe, Norway, 2UiT the arctic university of Norway, Tromso, Norway, 3UiT tha arctic university of Norway, Tromsoe, Norway

 12:10 - 12:20

THE IMPACT OF GENDER ON THE RISK OF CARDIOVASCULAR EVENTS IN PATIENTS WITH RHEUMATOID ARTHRITIS

  M. Adawi, A. Blum, Padeh and Ziv Hospitals, Azrieli Faculty of Medicine, Bar-Ilan University, Zefat, Israel

 12:20 - 12:30

THE ROLE OF ABNORMAL KARYOTYPE AND/OR CERTAIN SOMATIC MUTATIONS IN THE RISK OF AUTOINFLAMMATORY/AUTOIMMUNE DISORDERS IN PATIENTS WITH MYELODYSPLASTIC SYNDROME

 

A. Watad1, M. Kacar2, N.L. Bragazzi3, Q. Zhou2, E. Roman4, A. Smith4, R.A. Jones5, H. Amital1, C. Cargo5, D. Mcgonagle2, S. Savic2, 1Sheba Medical Center, Tel-Hashomer, Israel, 2Leeds University, Leeds, United Kingdom, 3University of Genoa, Genoa, Italy, 4University of York, York, United Kingdom, 5Leeds Teaching Hospitals, Leeds, United Kingdom

 685

10:30 - 12:30

PS42 - DILEMMAS IN DIAGNOSTIC NIKOS SKALKOTAS

 Moderation: A. Melegari1, N. Bizzaro2, 1OCSAE Hospital Modena, Laboratory Department, Modena, Italy, 2Azienda Sanitaria Universitaria Integrata di Udine, Laboratory Of Clinical Pathology, San Donà di Piave, Italy

 10:30 - 10:45

SCREENING AND DISEASE-ORIENTED PROFILES IN THE DIAGNOSIS OF AUTOIMMUNE RHEUMATIC DISEASES.

  N. Bizzaro, Azienda Sanitaria Universitaria Integrata di Udine, San Donà di Piave, Italy 10:45 - 11:00

THE CURRENT STATUS OF THE INTERNATIONAL CONSENSUS ON ANA PATTERNS (ICAP) AND FUTURE DIRECTIONS

  E. Chan, University of Florida, GAINESVILLE, United States of America 11:00 - 11:10

ACPA POSITIVE RA: A DISTINCT CLINICAL ENTITY?

  C. Perricone, Università degli Studi di Perugia, 06129, Italy 11:10 - 11:20

NEURONAL AUTOIMMUNOLOGY : AN INCREASING DIAGNOSTIC AND ASSOCIATION WITH THE DEMAND FOR OLIGOCLONAL BANDS IN LIQUOR

  A. Melegari1, C. Bonaguri2, A. Russo2, A. Picanza2, E. De Santis1, T. Trenti1, 1OCSAE Hospital Modena, Modena, Italy, 2University Hospital of Parma, Parma, Italy

 11:20 - 11:30

COMBINING ANTI-CCP ANTIBODY AND RHEUMATOID FACTOR ISOTYPE SPECIFIC TEST RESULTS INCREASES THE DIAGNOSTIC CONFIDENCE OF RHEUMATOID ARTHRITIS

  C. Konrad, M. Grundhuber, I. Gehring, S. Swiniarski, Thermo Fisher Scientific, Freiburg, Germany

 11:30 - 11:40

DEVELOPMENT OF AUTOANTIBODY SCREENING USING FULL LENGTH SECRETOME PROTEINS ON SUSPENSION BEAD ARRAYS AND PLANAR ARRAYS

 

J. Olofsson1, M. Andersson1, C. Hellström1, R. Sjöberg2, A. Månberg1, E. Pin3, P. Nilsson4, 1Div. of Affinity Proteomics, Dept. of Protein Science, KTH Royal Institute of Technology, Stockholm, Sweden, 2KTH - Royal Institute of Technology, Solna, Sweden, 3KTH - Scilifelab, Solna, Sweden, 4KTH - Scilifelab, Stockholm, Sweden

 11:40 - 11:50

AUTOMATED ANA PATTERN RECOGNITION ACCORDING TO ICAP NOMENCLATURE - CHALLENGES FOR ARTIFICIAL INTELLIGENCE

 

R. Hiemann1, A. Hiemann2, J. Noack3, A. Elimport4, P. Schierack3, K. Conrad5, D. Roggenbuck6, 1BTU Cottbus-Senftenberg, Senftenberg, Germany, 2Leipzig University, Leipzig, Germany, 3Brandenburg University of Technology Cottbus-Senftenberg Cottbus-Senftenberg, Senftenberg, Germany, 4Medipan GmbH, Dahlewitz, Germany, 5Technical University of Dresden, Dresden, Germany, 6Medipan GmbH, Dahlewitz / Berlin, Germany

 11:50 - 12:00

UNDERSTANDING THE BIOLOGICAL SIGNIFICANCE OF ANTI-DFS70 ANTIBODIES: IMPACT OF TNFALPHA BLOCKERS ON THEIR OCCURRENCE IN INFLAMMATORY ARTHRITIS.

 T. Carbone1, C. Esposito2, V. Pafundi3, A. Carriero1, M.C. Padula1, A. Padula1, S. D'Angelo1, 1Ospedale San Carlo, Potenza, Italy, 2Prato Hospital, Prato, Italy, 3Ospedale San carlo, Potenza, Italy

 12:00 - 12:10

ANTI-RA33 ANTIBODIES AS DIAGNOSTIC MARKERS IN EARLY RHEUMATOID ARTHRITIS

 

D. Sieghart1, M. Buch2, A. Burska2, M. Grundhuber3, S. Swiniarski3, P. Emery2, H. Haslacher1, S. Blüml1, D. Aletaha1, G. Steiner1, 1Medical University of Vienna, Vienna, Austria, 2University of Leeds, Leeds, United Kingdom, 3Thermo Fisher Scientific, Freiburg, Germany

 12:10 - 12:20

CONCORDANCE OF THE ANALYTICAL PERFORMANCE OF AUTOIMMUNE ANTIBODIES ON THE HOB BIOCLIA® 6500 AUTOMATED IMMUNOASSAY ANALYZER TO THE PHADIA 250® SYSTEM

  C. Knies1, P. Von Landenberg1, R. Tönnies2, M. Olivo2, 1LADR GmbH MVZ Nord-West, Schüttorf, Germany, 2medac GmbH, Wedel, Germany

 12:20 - 12:30

ISOLATED POSITIVITY FOR ANTI-RNP-A ANTIBODIES: IS IT A PREDICTIVE MARKER FOR DEVELOPMENT OF AUTOIMMUNITY?

 A. Serrano1, O. Cabrera-Marante1, F. Lozano Morillo2, L. Morillas2, L. Naranjo3, D. Pleguezuelo1, 1Hospital doce de octubre, madrid, Spain, 2Hospital Universitario 12 de Octubre, madrid, Spain, 3Hospital Universitario 12 de Octubre, MADRID, Spain

 700

10:30 - 12:30

PS43 - COVID19 (CORONA) AND AUTOIMMUNITY; AUTOIMMUNE CONDITIONS, CYTOKINES STORM AND HYPERFERRITINEMIA

MC3

  Moderation: R. Giacomelli, University of L'Aquila, Department Of Applied Clinical Sciences And Biotechnology, Rheumatology Unit, School Of Medicine, L'Aquila, Italy

 10:30 - 10:50

sars-cov2 and inflammatory response

  R. Giacomelli, University of L'Aquila, L'Aquila, Italy 

71010:30 - 12:30

PS44 - THE HEART AND LUNG IN AUTOIMMUNE CONDITIONS

MC2

  Moderation: M. Galeazzi1, E. Matsuura2, 1 , Italy, 2Okayama University, Neutron Therapy Research Center/graduate School Of Medicine, Dentistry, And Pharmaceutical Sciences,

Okayama, Japan 10:30 - 10:50

ARTERIAL HYPERTENSION IN CHRONIC ARTHRITIS

  R. Gerli, , Italy 10:50 - 11:10

CARDIOVASCULAR CO-MORBIDITY IN AUTOIMMUNE RHEUMATIC DISEASES: PREDICTION, MONITORING AND PREVENTION

  G. Kitas, DUDLEY GROUP NHS FOUNDATION TRUST, DUDLEY, United Kingdom 11:10 - 11:30

THERANOSCTICS APPROACHES TO AUTOIMMUNE AND ATHEROSCLEROTIC DISEASE AND CANCER

  E. Matsuura, Okayama University, Okayama, Japan 11:30 - 11:50

NON-ISCHEMIC HEART CONDITIONS IN AUTOIMMUNE DISEASES

  Z. Szekanecz, , Hungary 11:50 - 12:00

EVALUATION OF MYOCARDIAL GENE EXPRESSION PROFILING FOR SUPERIOR DIAGNOSIS OF IDIOPATHIC GIANT CELL MYOCARDITIS IN A LARGE COHORT OF PATIENTS WITH ACUTE CARDIAC DECOMPENSATION

  H.-P. Schultheiss1, F. Escher2, 1Institute of Cardiac Diagnostics and Therapy , Berlin, Germany, 2Charite , Berlin, Germany

 12:00 - 12:10

CLINICAL CHARACTERISTICS AND OUTCOME OF ILD-ONSET RHEUMATOID ARTHRITIS AND ACPA-POSITIVE ILD

  R. Chen, L. Zhao, X. Xiao, H. Chen, X. Zhang, Peking Union Medical College Hospital, Beijing, China

 12:10 - 12:20

A SYSTEMIC REVIEW OF FACTORS ASSOCIATED WITH PULMONARY ARTERIAL HYPERTENSION (PAH) IN SYSTEMIC SCLEROSIS (SSC)

  Y. Jiang, M. Turk, J. Pope, St. Joseph's Health Care, London, Canada 

72010:30 - 12:30

PS45 - AUTOIMMUNE DISEASE; NOVEL ASPECTS KOKKALI

 10:30 - 10:50

ALLERGY AND AUTOIMMUNITY

  A.S. Tanay, Ramat Gan, Israel

 10:50 - 11:10

CYTOTOXIC T-CELLS AND CSF-BRAIN BARRIER DAMAGE IN THE ASD BRAIN

  M. Anderson, Beth Israel Deaconess Medical Center, Boston, United States of America 11:10 - 11:30

ENGINEERED T LYMPHOCYTES TO TREAT NEURO-INFLAMMATORY DISEASES

  P. Ashton-Rickardt, AZTherapies, Inc, Boston, United States of America 11:30 - 11:50

AN INNOVATIVE BUSINESS MODEL FOR CHRONIC DISEASE TREATMENT AVAILABILITY BASED ON A STATE-OF-THE-ART MANUFACTURING PLATFORM.

  J. Castillo, Univercells, Charleroi, Belgium 11:50 - 12:00

THE EFFECT OF IL-1 BLOCKERS ON EXERTIONAL LEG PAIN IN FMF PATIENTS

  A. Druyan1, I. Ben Zvi2, M. Lidar3, 1sheba medical center, tel hashomer, ramat gan, Israel, 2Tel-Aviv University, Tel Aviv, Israel, 3Tel Aviv University, Tel Aviv, Israel

 725

10:30 - 12:30

PS46 - FATIGUE AND AUTOIMMUNE DISEASE CONFERENCE ROOM 1

 Moderation: G. Halpert1, V. Ryabkova2, 1Sheba Medical Center, Zabludowicz Center For Autoimmune Diseases, Ramat Gan, Israel, 2Saint Petersburg State University, Laboratory Of The Mosaic Of Autoimmunity, Saint Petersburg, Russian Federation

 10:30 - 10:50

AUTOIMMUNITY TO AUTONOMIC NERVE SYSTEM AS A CAUSE OF FATIGUE

  G. Halpert, Sheba Medical Center, Ramat Gan, Israel 10:50 - 11:10

FATIGUE IN AUTOINFLAMMATORY/AUTOIMMUNITY SYNDROME INDUCED BY ADJUVANTS (SHOENFELD’S SYNDROME) DUE TO FOREIGN BODY IMPLANTATION: A COMPARISON WITH FATIGUE IN FIBROMYALGIA

  J.W. Cohen Tervaert1, N. Mohazab2, C. Van Eeden2, M. Osman2, 1 , Canada, 2university of alberta, edmonton, Canada

 11:10 - 11:30

FATIGUE IN AUTOIMMUNE DISEASES - HOW CAN WE MANAGE IT?

  V. Ryabkova1, L. Churilov2, Y. Shoenfeld3, 1Saint Petersburg State University, Saint Petersburg, Russian Federation, 2Laboratory of the Mosaic of Autoimmunity, Saint-

Petersburg, Russian Federation, 3Sheba Medical Center, Tel Aviv, Israel 11:30 - 11:50

Autoimmunity-related risk variants in PTPN22and CTLA4 are associated with ME/CFS with infectious onset

  C. Scheibenbogen, Charité, Berlin, Germany 

73012:30 - 14:00

LUNCH BREAK, EXHIBITION, POSTERS EXHIBITION HALL

74512:30 - 14:00

INDUSTRY SUPPORTED SESSION NIKOS SKALKOTAS

  Moderation: Y. Kazuhiko1, T. Koike2, 1Riken Center For Integrative Medical Sciences, Japan, 2Hokkaido Medical Center for Rheumatic Diseases, Supreme Advisor, Sapporo, Japan

 12:30 - 12:30

WORKSHOP IS ORGANIZED AND SUPPORTED BY Chugai Pharmaceutical

  

75014:00 - 16:00

PS47- NOVEL THERAPIES IN AUTOIMMUNE DISEASES

ALEXANDRA TRIANTI

  Moderation: R. Milo1, D. Naor2, 1 , Israel, 2Hebrew University, Lautenberg Center Of Immunology And Cancer Reaserch Faculty Of Medicine, Jerusalem, Israel

 14:00 - 14:20

THE ROLE OF B CELLS AND B CELL TARGETED THERAPIES IN MULTIPLE SCLEROSIS

  R. Milo, , Israel 14:20 - 14:40

TARGETING THE HEME OXYGENASE-CARBON MONOXIDE PATHWAY AS NOVEL THERAPEUTIC APPROACHES FOR THE TREATMENT OF AUTOIMMUNE DISEASES

  F. Nicoletti, University of Catania, Catania, Italy 14:40 - 15:00

ANTI-INFLAMMATORY AND ANTI-NEURODEGENERATIVE THERAPEUTIC ACTIVITY OF HUMAN 5-MER PEPTIDE (MTADV), TARGETING SERUM AMYLOID: NEW POTENTIAL DRUG AND TARGET

  D. Naor, Hebrew University, Jerusalem, Israel 

15:00 - 15:20

THE CONCEPT OF IMMUNE SYSTEM REBOOT THERAPY (ISRT) IN AUTOIMMUNE DISEASES

  S. Ntshalintshali, Tygerberg Hospital, Cape Town, South Africa 15:20 - 15:30

TUFTSIN-PHOSPHORYLCHOLINE (TPC) EFFECTIVENESS IN THE AMELIORATION OF LUPUS NEPHRITIS IN A MICE MODEL

 

A. Shemer1, S. Kivity1, O. Shovman1, T. Bashi1, O. Perry1, A. Watad1, D. Ben-Ami Shor1, A. Volkov1, I. Barshack1, N.L. Bragazzi2, A. Krule1, M. Fridkin3, H. Amital1, M. Blank1, Y. Shoenfeld4, 1Sheba Medical Center, Tel-Hashomer, Israel, 2University of Genoa, Genoa, Italy, 3The Weizmann Institute of Sciences, Rehovot, Israel, 4Sheba Medical Center, Tel Aviv, Israel

 15:30 - 15:40

THERAPEUTIC PLASMA EXCHANGE IN AUTOINMUNE NEUROLOGICAL DISEASES

 I. Nieto-Aristizábal1, Á. Vivas2, P. Ruiz2, C. Aragon2, I. Posso-Osorio1, J. Quiñones3, J. Rivillas2, G.J. Tobón1, 1Fundación Valle del Lili, Universidad Icesi, Cali, Colombia, 2Universidad Icesi, Cali, Colombia, 3Fundación Valle del Lili, Cali, Colombia

 15:40 - 15:50

DECIPHERING THE ROLE OF CLATHRIN MEDIATED ENDOCYTOSIS IN AUTOIMMUNE DISEASES

  S. Carmel1, E. Yefenof2, H. Ovadia3, 1 Ramat Hasharon, Israel, 2The hebrew University, Jerusalem, Israel, 3Hadassah-Hebrew University Medical Center, Jerusalem, Israel

 760

14:00 - 16:00

PS48 - MYASTHENIA GRAVIS AND MULTIPLE SCLEROSIS

BANQUETING

 Moderation: A. Antonelli1, F.J. Authier2, 1University of Pisa, Department Of Clinical And Experimental Medicine, Pisa, Italy, 2Paris Est Creteil University, Inserm Imrb U955 Team 10, Creteil, France

 14:00 - 14:10

SERUM LEVELS OF SOLUBLE TWEAK ARE SIGNIFICANTLY ELEVATED DURING MULTIPLE SCLEROSIS.

 

S. Carmona1, X. Ayrignac2, T. Vincent2, C. Carra-Dallière2, M. Charif2, J.-P. Dales1, F. Pinna2, P. Labauge3, S. Desplat-Jego4, 1Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, Marseille, France., Marseille, France, 2Montpellier Univesity Hospital, Montpellier, France, 3Département de Neurologie, CRC sclérose en plaques, CHU Montpellier, Univ Montpellier, Montpellier, France, 4Aix Marseille Université/ AP-HM, Marseille, France

 14:10 - 14:20

ANTIGEN PRESENTATION BY TOLEROGENIC DENDRITIC CELLS (TOLDCS )

TO TREAT MULTIPLE SCLEROSIS (MS)

 M. Rodi1, A.-L. De Lastic1, S. Antonopoulou1, C. Kylintireas2, J. Matsoukas3, A. Mouzaki1, 1Medical School, University of Patras, Patras, Greece, 2Medical School, National and Kapodistrian University of Athens, Athens, Greece, 3NewDrug, Patras, Greece

 14:20 - 14:30

THE ROLE OF TRANSCRIPTION FACTOR ETS-2 IN THE PATHOGENESIS OF MULTIPLE SCLEROSIS (MS) AND EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (EAE)

 

I. Panagoulias1, I. Aggeletopoulou1, E. Kourepini2, C. Kylintireas3, A. Mouzaki1, 1Medical School, University of Patras, Patras, Greece, 2Biomedical Research Foundation of the Academy of Athens, Athens, Greece, 3Medical School, National and Kapodistrian University of Athens, Athens, Greece

 14:30 - 14:40

ANTIGEN-SPECIFIC TOLERANCE INDUCTION AS A THERAPY FOR MYASTHENIA GRAVIS

  K. Lazaridis, V. Baltatzidou, E. Ntoukaki, A.M. Maniou, Hellenic Pasteur Institute, Athens, Greece

 14:40 - 14:50

IGD-CD27- DOUBLE NEGATIVE B CELLS IN MULTIPLE SCLEROSIS PATIENTS ARE MATURE MEMORY CELLS THAT CAN MIGRATE TOWARDS PRO-INFLAMMATORY CHEMOKINES

 L. Beckers1, G. Montes Diaz1, L. Villar2, B. Van Wijmeersch3, V. Popescu3, V. Somers1, J. Fraussen1, 1Hasselt University, Diepenbeek, Belgium, 2Hospital Universitario Ramón y Cajal, Madrid, Spain, 3Rehabilitation & MS-Center, Pelt, Belgium

 14:50 - 15:00

BLOCKING THE IL-23/TH17 PATHWAY AMELIORATES MYASTHENIA GRAVIS SYMPTOMS IN AUTOIMMUNE MYASTHENIA GRAVIS MOUSE MODEL

  J. Villegas1, S. Berrih-Aknin1, R. Le Panse1, N. Dragin2, 1Sorbonne university, Inserm umrs 974, PARIS, France, 2Sorbonne university, Inserm umrs 974 , PARIS, France

 15:00 - 15:10

RISK FACTORS ASSOCIATED WITH MYASTHENIA GRAVIS IN THYMOMA PATIENTS: A LINK WITH ECTOPIC GERMINAL CENTERS

 

C. Lefeuvre1, C. Payet1, O.-M. Fayet1, S. Maillard1, F. Truffault1, V. Bondet2, D. Duffy3, V. De Montpreville4, M.R. Ghigna4, E. Fadel4, A. Mansuet-Lupo5, M. Alifano5, P. Validire6, D. Gossot6, A. Behin7, B. Eymard8, S. Berrih-Aknin9, R. Le Panse9, 1Myology research center, PARIS, France, 2Institut Pasteur, Paris, France, 3Institut Pasteur, PARIS, France, 4Marie Lannelongue Hospital, Le Plessis Robinson, France, 5Cochin University Hospital Group, Paris, France, 6Institut Mutualiste Montsouris, Paris, France, 7Institute of Myology, Pitié-Salpêtrière Hospital, PARIS, France, 8AP-HP, Referral center for neuromuscular disorders, Paris, France, 9Sorbonne university, Inserm umrs 974, PARIS, France

 15:10 - 15:20

INVESTIGATION OF GLUCOCORTICOID SENSITIVITY IN MULTIPLE SCLEROSIS PATIENTS IN RELAPSE

 N.N. Ansari1, M.E. Evangelopoulos2, E. Kassi1, K. Sfagos2, P. Moutsatsou1, 1University of Athens, Medical School, Athens, Greece, 2Eginition University Hospital- National and Kapodistrian University of Athens, Athens, Greece

 15:20 - 15:30

STUDY OF INTFERFETON TYPE I SIGNATURE IN AUTOIMMUNE MYASTHENIA GRAVIS

 

C. Payet1, F. Truffault1, V. Bondet2, D. Duffy3, F. Bolgert4, A. Behin5, S. Berrih-Aknin6, R. Le Panse6, 1Myology research center, PARIS, France, 2Institut Pasteur, Paris, France, 3Institut Pasteur, PARIS, France, 4AP-HP Pitié-Salpêtrière Hospital, PARIS, France, 5Institute of Myology, Pitié-Salpêtrière Hospital, PARIS, France, 6Sorbonne university, Inserm umrs 974, PARIS, France

 15:30 - 15:40

PRO-RESOLVING LIPID MEDIATORS IN THE RESOLUTION OF MULTIPLE SCLEROSIS: NOVEL PATHOGENIC IMPLICATIONS FOR AUTOIMMUNITY AND NEUROINFLAMMATION

  V. Chiurchiu, IRCCS Santa Lucia Foundation, Rome, Italy 15:40 - 15:50

THE PREVALENCE OF MIGRAINE IN MULTIPLE SCLEROSIS (MS): A SYSTEMATIC REVIEW AND META-ANALYSIS.

 M. Ghajarzadeh1, A. Azimi2, O. Mirmosayeb3, M. Barzegar3, N. Nehzat3, V. Shaygannejad3, 1tums, , Iran, 2TUMS, tehran, Iran, 3Isfahan Neurosciences Research Center, Isfahan University of medical sciences, Isfahan, Iran,, isfahan, Iran

 15:50 - 16:00

TREATMENT OF MULTIPLE SCLEROSIS PATIENTS WITH AUTOLOGOUS REGULATORY T CELLS CD4+CD25+FOXP3+CD127LOW

 

S. Bykovskaia1, D. Eliseeva2, E. Zotkin3, E. Lyssuk1, A. Vasiliev2, J. Thorball4, M. Zaharova2, A. Lila3, E. Nasonov5, 1Pirogov Russian National Research Medical University, Moscow, Russian Federation, 2Neurology Scientific Research Institute, Moscow, Russian Federation, 3V.A.Nasonova Research Institute of Rheumatology, Moscow, Russian Federation, 4Rigi Care, Weggis, Switzerland, 5V.A. Nasonova Research Institute of Rheumatology, Moscow, Russian Federation

 770

14:00 - 16:00

PS49 - CELIAC AND GASTROINTESTINAL AUTOIMMUNE ASPECTS

NIKOS SKALKOTAS

  Moderation: S. De Carolis1, T. Matthias2, 1Fondazione Policlinico Gemelli IRCCS , Obstetrics And Gynaecology, Rome, Italy, 2AESKU.GROUP, Ceo, Wendelsheim, Germany

 14:00 - 14:20

SUPERFAMILY OF THE TRANSGLUTAMINASES: ARE PHAGES A FAMILY MEMBER?

  A. Lerner, A. Ramesh, T. Matthias, AESKU.GROUP, Wendelsheim, Germany 14:20 - 14:40

NEO-EPITOPE TISSUE TRANSGLUTAMINASE IS THE BEST, AND NEO-EPITOPE MICROBIAL TRANSGLUTAMINASE IS A NEW BIOMARKER FOR CELIAC DISEASE DIAGNOSIS

  T. Matthias, S. Neidhöfer, P. Wusterhausen, A. Heller, A. Lerner, AESKU.GROUP, Wendelsheim, Germany

 14:40 - 14:50

ANTI TRANSGLUTAMINASE (TTG) ANTIBODIES COULD PREDICT THE DEVELOPMENT OF CELIAC DISEASE 5 YEARS BEFORE THE DIAGNOSIS

  G. Previtali, E. Cimpoies, M. Seghezzi, V. Moioli, R. Ravasio, M.G. Alessio, ASST Papa Giovanni XXIII, Bergamo, Italy

 14:50 - 15:00

LUPUS ANTICOAGULANT REMISSION AFTER GLUTEN-FREE DIET IN A COELIAC PREGNANT WOMAN

 S. De Carolis1, S. Tabacco2, C. Garufi2, S. Salvi3, A. Caneschi3, A. Giannini2, A. Botta3, A. Lanzone3, 1Fondazione Policlinico Gemelli IRCCS , Rome, Italy, 2"Sapienza" Università di Roma, Rome, Italy, 3Fondazione Policlinico Gemelli IRCCS, Rome, Italy

 15:00 - 15:10

OLMESARTAN ENTEROPATHY DRESSED UP AS CELIAC DISEASE: A CASE REPORT

  M.G. Alessio, M. Seghezzi, G. Previtali, ASST Papa Giovanni XXIII, Bergamo, Italy 15:10 - 15:20

TEMPERATURE, PH DEPENDENCY, AND ACTIVITY OF MICROBIAL TRANSGLUTAMINASE AND ITS GLIADIN CROSS-LINKED NEO-COMPLEXES

  A. Ramesh, A. Lerner, T. Matthias, AESKU.GROUP, Wendelsheim, Germany 15:20 - 15:30

IDS-ISYS MULTI-DISCIPLINE AUTOMATED SYSTEM IS A SIMPLE AND RELIABLE TOOL FOR CELIAC DISEASE DIAGNOSIS

  M. Lambert1, S. Desplat-Jego2, 1Service d'Immunologie - LBM AP-HM, Marseille, France, 2Aix Marseille Université/ AP-HM, Marseille, France

 15:30 - 15:40

CLINICAL STUDY OF APTIVA CELIAC DISEASE IGA AND IGG REAGENTS ON PATIENTS WITH BIOPSY RESULTS

  A. Seaman1, M.G. Alessio2, E. Wahl3, J. Mangat3, J. Nibecker1, O. Springfield1, C. Bentow1, G. Previtali2, M. Mahler1, 1Inova Diagnostics, San Diego, United States of

America, 2ASST Papa Giovanni XXIII, Bergamo, Italy, 3Inova Diagnostics, Inc, San Diego, United States of America

 15:40 - 15:50

PREVALENCE OF DAIRY IMMUNE REACTIVITY IN PATIENTS WITH POSITIVE SEROLOGY FOR CELIAC DISEASE

  J. Lambert, L. Gushgari, S. Mejia, C. Salazar, Cyrex Laboratories, LLC, Phoenix, United States of America

 780

14:00 - 16:00

PS50 - THE INVOLVEMENT OF AUTOIMMUNITY IN CNS MC3

 

Moderation: L. Andreoli1, P. Sobolevskaia2, 1ASST Spedali Civili, Brescia; University of Brescia, Rheumatology And Clinical Immunology Unit, Brescia, Italy, 2Saint-Petersburg State University, Laboratory Of The Mosaic Of Autoimmunity, Saint-Petersburg, Russian Federation

 14:00 - 14:15

NEW AUTOANTIBODIES IN AUTOIMMUNE NEUROLOGICAL DISEASE

  S. Naides, Euroimmun US, a PerkinElmer company, Mountain Lakes, United States of America

 14:15 - 14:30

THE CONCEPTS OF INDUCTION THERAPY AND IMMUNE RECONSTITUTION (IRT) AS NEW AND HIGHLY EFFECTIVE TREATMENT MODELS, IN MULTIPLE SCLEROSIS

  D. Karussis, , Israel 14:30 - 14:40

THE IMMUNOLOGIC ETIOLOGY OF PSYCHIATRIC MANIFESTATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS: A NARRATIVE REVIEW ON THE ROLE OF THE BLOOD BRAIN BARRIER, ANTIBODIES, CYTOKINES AND CHEMOKINES

 

S. Deijns1, J. Broen2, N. Kruyt3, C. Schubart4, L. Andreoli5, A. Tincani6, M. Limper7, 1 Houten, Netherlands, 2Maxima Medical Centre, Eindhoven, Netherlands, 3Leiden University Medical Centre, Leiden, Netherlands, 4Tergooi hospital, Blaricum, Netherlands, 5ASST Spedali Civili, Brescia; University of Brescia, Brescia, Italy, 6 , Italy, 7University Medical Center Utrecht, Utrecht, Netherlands

 14:40 - 14:50

PROLACTIN, AUTOIMMUNITY AND BREAST IMPLANTS.

  L. Jara, Instituto Mexicano del Seguro Social, Mexico City, Mexico 14:50 - 15:00

AIT AND PSYCHIATRIC DISORDERS- IS THERE ANYTHING COMMON?

 

P. Sobolevskaia1, L. Churilov2, V. Utekhin3, T. Fedotkina3, B. Gilburd4, A. Gvozdetskiy1, 1Saint-Petersburg State University, Saint-Petersburg, Russian Federation, 2Laboratory of the Mosaic of Autoimmunity, Saint-Petersburg, Russian Federation, 3Saint Petersburg State University, Saint-Petersburg, Russian Federation, 4Sheba Medical Center, Ramat Gan, Israel

 15:00 - 15:10

ANTI-FGFR3 ANTIBODY EPITOPES ARE FUNCTIONAL SITES AND CORRELATE WITH THE NEUROPATHY PATTERN

 

Y. Tholance1, L. Mohr2, M. Jung3, E. Reynaud-Federspiel2, K. Ferraud1, J.-P. Camdessanché1, J.-C. Antoine1, C. Moritz2, 1CHU Saint-Étienne, Saint-Étienne, France, 2Institut NeuroMyoGène, Saint-Étienne, France, 3Saarland University, Homburg, Germany

 15:10 - 15:20

AUTOIMMUNE CONCEPT OF SCHIZOPHRENIA: HYPOTHESES AND FACTS

 

M. Mayorova1, B. Gilburd2, N. Petrova1, L. Churilov3, Y. Shoenfeld4, 1Saint-Petersburg University, Saint-Petersburg, Russian Federation, 2Sheba Medical Center, Ramat Gan, Israel, 3Laboratory of the Mosaic of Autoimmunity, Saint-Petersburg, Russian Federation, 4Sheba Medical Center, Tel Aviv, Israel

 15:20 - 15:30

NEUROLOGICAL INVOLVEMENT IN EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS (EGPA) – IS THERE A DIFFERENCE IN BIOLOGICAL BIOMARKERS?

  A. Girão, I. Gomes, J. Fernandes, J. Gomes, J. Ribeiro, R. Pina, L. Santos, A. Carvalho, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal

 15:30 - 15:40

EXPOSED HYDROPHOBICITY IN PROTEINS: THE COMMON LINK BETWEEN AUTOIMMUNITY AND NEURODEGENERATIVE DISEASES

  D. Butnaru1, J. Chapman2, 1Hospital Clínico San Carlos, MADRID, Spain, 2Sheba Medical Center, Israel, Ramat Gan, Israel

 15:40 - 15:50

EFFECTS OF SAFFLOWER YELLOW PIGMENT ON THE SPLEEN CELLS OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS MICE

 

L.-J. Song1, Q. Wang2, J. Wang3, Z.-B. Ding3, J.-Z. Yu4, J.-W. Yu4, Z. Chai5, B.-G. Xiao6, C.-G. Ma7, 1Shanxi University of Traditional Chinese Medicine, Taiyuan, China, 2Shanxi University of Chinese Medicine, Taiyuan, China, 3Shanxi Medical University, Taiyuan, China, 4Shanxi Datong University, Datong, China, 5Shanxi University of Chinese Medicine, Jinzhong, China, 6Fudan University, Shanghai, China, 7Shanxi university of chinese medicine, Jinzhong, China

 790

14:00 - 16:00

PS51 - AUTOIMMUNE DISEASES: CASE REPORTS MC2

 Moderation: C. Edwards1, M. Ehrenfeld2, D. D'Cruz3, 1NIHR Clinical Research Facility, University Hospital Southampton, Rheumatology, Southampton, United Kingdom, 2 , Israel, 3 , United Kingdom

 14:00 - 14:10

ATYPICAL HEMOLYTIC UREMIC SYNDROME IN A PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS-LIKE DISEASE AND ANTIPHOSPHOLIPID SYNDROME (APS)

 F. Zunica1, F. Ricci2, S. Rossi2, L. Palumbo2, C. Gualeni2, R. Badolato1, M. Cattalini1, 1University of Brescia, Brescia, Italy, 2University of Brescia ans ASST Spedali Civili di Brescia, Brescia, Italy

 14:10 - 14:20

PATIENTS WITH PERIODIC FEVER, APHTHOUS STOMATITIS, PHARYNGITIS AND ADENITIS (PFAPA) SYNDROME HAVE ALTERED METHYLATION PATTERNS IN PIK3AP1 (BCAP) AND SPON2 (SPONDIN-2) GENES

 

E. Lovsin1, J. Kovac2, T. Tesovnik2, N. Toplak2, D. Perko2, T. Rozmaric3, M. Debeljak2, T. Avcin4, 1UKC Ljubljana, Ljubljana, Slovenia, 2Ljubljana University Medical Centre, Ljubljana, Slovenia, 3Medical University of Vienna, Vienna, Austria, 4Children's Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia

 14:20 - 14:30

AN IDIOPATHIC CASE OF COMBINED WARM AND COLD AIHA

  A. Figueiredo, N. Vieira E Brito, J. Oliveira, P. Alcântara, Centro Hospitalar Lisboa Norte, Lisboa, Portugal

 14:30 - 14:40

FROM INFLUENZA TO STROKE: A MOSAIC OF MECHANISMS LINKING THE VIRUS, THE VACCINE AND THE DISEASE.

 V. Borba1, D. Kanduc2, V. Ryabkova3, Y. Shoenfeld4, 1Zabludowicz Center for Autoimmune Diseases, Tel-Hashomer, Portugal, 2University of Bari, Bari, Italy, 3Saint Petersburg State University, Saint Petersburg, Russian Federation, 4Sheba Medical Center, Tel Aviv, Israel

 14:40 - 14:50

NEUROMYELITIS OPTICA SPECTRUM DISORDERS (NMOSD) AND SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): DOUBLE DISEASE BURDEN AND DILEMMA

  A. Abou-Raya1, S. Abou-Raya2, 1Faculty of Medicine, University of Alexandria, 00203, Egypt, 2Faculty of Medicine, University of Alexandria, Alexandria, Egypt

 14:50 - 15:00

THE RISK OF INFECTION IN PATIENTS WITH POLYMYOSITIS AND DERMATOMYOSITIS TREATED WITH DIVERSE IMMUNOSOPRESSIVE THERAPY: A LARGE CROSS-SECTIONAL STUDY

  N. Mahroum1, A. Watad2, N.L. Bragazzi3, D. Comaneshter4, A. Cohen5, H. Amital2, 1Sheba

Medical Center, Ramat Gan, Israel, 2Sheba Medical Center, Tel-Hashomer, Israel, 3University of Genoa, Genoa, Italy, 4Clalit Health Services, tel aviv, Israel, 5Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel

 800

14:00 - 16:00

PS52- TYPE 1 DIABETES MELLITUS KOKKALI

 Moderation: M.G. Von Herrath1, A. Afek2, 1La Jolla Institute for Immunology, Developmental Immunology, La Jolla, United States of America, 2Sheba Medical Center, Managment, Ramat-Gan, Israel

 14:00 - 14:20

TREATMENT OF TYPE 1 DIABETES WITH COMBINATION THERAPIES -CHALLENGES AND NEW CLINICAL INSIGHTS

  M.G. Von Herrath, La Jolla Institute for Immunology, La Jolla, United States of America 14:20 - 14:40

THE EFFECTS OF IMMIGRATION AND ACCULTURATION OF T1DM

  A. Afek, Sheba Medical Center, Ramat-Gan, Israel 14:40 - 14:50

PERFORMANCE OF A NOVEL FULLY AUTOMATED IMMUNOASSAY FOR THE DIAGNOSIS OF ANTI-GAD65 AUTOANTIBODIES IN AUTOIMMMUNE TYPE 1 DIABETES

  D. Filchtinski, J. Schulte-Pelkum, Phadia GmbH, Freiburg, Germany 14:50 - 15:00

PROTEIN-ENGINEERED MOLECULES CARRYING GAD65 EPITOPES AND TARGETING CR1 SELECTIVELY DOWN-MODULATES DISEASE-ASSOCIATED HUMAN B LYMPHOCYTES

 A. Tchorbanov1, I. Manoylov1, G. Boneva1, I. Doytchinova2, N. Mihaylova1, 1Institute of microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria, 2Medical University of Sofia, Sofia, Bulgaria

 15:00 - 15:10

URBANIZATION AND TYPE 1 DIABETES MELLITUS IN CHILDREN 0-14 YEARS

 L. Soprun1, V. Utekhin1, L. Churilov2, 1St.Petersburg State University, Saint-Petersburg, Russian Federation, 2Laboratory of the Mosaic of Autoimmunity, Saint-Petersburg, Russian Federation

 15:10 - 15:20

CLONAL MOSAICISM IN AUTOREACTIVE T CELLS IN DIABETIC NOD MICE

  M. Alriyami1, L. Marchand2, Q. Li3, X. Du2, M. Olivier2, C. Polychronakos2, 1Sultan Qaboos University , Muscat, Oman, 2McGill University Health Centre Research Institute, Montreal,

Canada, 3University of Toronto, Toronto, Canada 15:20 - 15:30

116C-NOD GUT MICROBIOTA MODULATES TH RESPONSE AND AUTOIMMUNE DIABETES INCIDENCE OF NOD MICE

 

E. Rosell-Mases1, A. Santiago2, M. Pozuelo2, M. Corral-Pujol3, C. Cosovanu4, M. Lleal2, J. Willamil2, F. Yáñez2, L. Egia-Mendikute4, E. Cosp2, C. Santos-Rosendo4, C. Vived4, J. Luna4, C. Mora4, C. Manichanh2, J. Verdaguer4, 1University of Lleida / IRBLleida, Lleida, Spain, 2Vall d'Hebron Research Institute, Barcelona, Spain, 3Universitat de Lleida/IRB Lleida, Lleida, Spain, 4Faculty of Medicine, University of Lleida and IRBLleida, Lleida, Spain

 15:30 - 15:40

RISK OF INCIDENT DIABETES MELLITUS ASSOCIATED WITH HYDROXYCHLOROQUINE, METHOTREXATE, BIOLOGICS AND CORTICOSTEROIDS IN RHEUMATOID ARTHRITIS: A META-ANALYSIS OF OBSERVATIONAL STUDIES

  W. Xie, Peking University First Hospital, Beijing, China 15:40 - 15:50

THE IMPACT OF ORAL VERSUS INTRA-PERITONEAL METFORMIN ON INTERLEUKIN-17 LEVELS OF PRISTANE INDUCED FEMALE BALB/C MICE

 

S. Sumantri1, M. Hatta2, I. Rengganis3, H. Rasyid2, 1Faculty of Medicine, Universitas Pelita Harapan, Kabupaten Tangerang, Indonesia, 2Faculty of Medicine, Universitas Hasanuddin Makassar, Makassar, Indonesia, 3Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia

 15:50 - 16:00

ASSOCIATION OF CHANGES IN ADAPTIVE IMMUNE CELL COMPARTMENT WITH AGE, SERUM C-PEPTIDE LEVEL AND METABOLIC STATUS IN YOUNG NEWLY DIAGNOSED TYPE 1 DIABETES PATIENTS

  A. Oras1, A. Peet1, T. Giese2, V. Tillmann1, R. Uibo1, 1University of Tartu, Tartu, Estonia, 2Universitätsklinikum Heidelberg, Heidelberg, Germany

 810

14:00 - 16:00

PS53 - IMMUNE DEFICIENCY AND AUTOIMMUNITY CONFERENCE ROOM 1

  Moderation: C. Lunardi1, L. Andrade2, 1 , Italy, 2Universidade Federal de São Paulo, Escola Paulista de Medicina, Rheumatology Division, São Paulo, Brazil

 14:00 - 14:20

NEXT-GENERATION FC RECEPTOR–TARGETING BIOLOGICS FOR AUTOIMMUNE DISEASES [TOPIC: IVIG]

  F. Käsermann1, R. Spirig1, A. Baz Morelli2, A. Zuercher1, 1CSL Behring, Bern, Switzerland, 2CSL Ltd, Parkville, Australia

 

14:20 - 14:40

A CENTURY AND STILL GOING STRONG: IVIG IN IMMUNODEFICIENCY AND AUTOIMMUNITY

  S. Kaveri., cnrs, Paris, France 14:40 - 15:00

IMMUNODEFICIENCY AND AUTOIMMUNITY

  C. Lunardi, , Italy 15:00 - 15:20

MULTIPLE INTERSECTIONS BETWEEN SYSTEMIC LUPUS ERYTHEMATOSUS AND IMMUNODEFICIENCY

  L. Andrade, Universidade Federal de São Paulo, Escola Paulista de Medicina, Sao Paulo, Brazil

 15:20 - 15:30

MANAGEMENT OF SECONDARY ANTIBODY DEFICIENCY WITH INTRAVENOUS IMMUNOGLOBULIN IN PATIENTS WITH PREVIOUS THERAPY WITH RITUXIMAB

 J. Carbone1, M. Di Natale1, J. Ovalles2, J. Martinez2, J. Navarro2, J. Gil2, E. Sarmiento3, 1Hospital general Universitario Gregorio Marañon, Madrid, Spain, 2Hospital General Universitario Gregorio Marañon, Madrid, Spain, 3Clinica Santa Elena, Madrid, Spain

 15:30 - 15:40

ANTI-CD45RC MAB IMMUNOTHERAPY CONTROLS THE DEVELOPMENT OF AUTO-IMMUNE SYMPTOMS IN AN APECED RAT MODEL OF AIRE DEFICIENCY

 

M. Besnard1, J. Ossart2, C. Usal2, N. Vimond2, H. Règue2, L. Flippe2, A. Ranki3, P. Peterson4, C. Guillonneau2, 1Center of Research in Transplantation and Immunology, CRTI - UMR1064, Nantes, France, 2Nantes Université, INSERM, Nantes, France, 3Helsinki University Central Hospital, Helsinki, Finland, 4University of Tartu, Tartu, Estonia

 15:40 - 15:50

THE PREVALENCE AND CLINICAL SIGNIFICANCE OF AUTOANTIBODIES IN PATIENTS WITH COMMON VARIABLE IMMUNODEFICIENCY

  T. Milota, Motol University Hospital, Prague, Czech Republic 15:50 - 16:00

AUTOIMMUNITY IN WISKOTT-ALDRICH SYNDROME; DOES IT MATTER!

  R. Rikhi, A. Jindal, A. Rawat, D. Suri, S. Singh, Postgraduate Institute of Medical Education and Research, Chandigarh, India

 810

16:00 - 16:30

COFFEE BREAK, EXHIBITION, POSTERS EXHIBITION HALL

820

16:30 - 18:30

PS54 - SLE, WHAT'S NEW? ALEXANDRA TRIANTI

  Moderation: A. Doria1, G.C. Tsokos2, M. Schneider3, 1 , Italy, 2Harvard Medical School, Medicine, BROOKLINE, United States of America, 3 , Germany

 16:30 - 16:50

NEW THERAPEUTIC STRATEGIES IN SLE MANAGEMENT

  A. Doria, , Italy 16:50 - 17:10

THE CD72-SEMA3A AXIS IN SLE PATHOGENESIS

  Z. Vadasz, , Israel 17:10 - 17:30

SYSTEMIC LUPUS ERYTHEMATOSUS: DIAGNOSTIC DIFFICULTIES

  D. D'Cruz, , United Kingdom 17:30 - 17:40

HSA_CIRC_0123190 IS INVOLVED IN PATHOGENESIS OF LUPUS NEPHRITIS BY SPONGING HAS-MIR-483-3P

  Z. Zheng1, C. Zhang2, 1Zhengzhou University, Zhengzhou, China, 2The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China

 17:40 - 17:50

MESENCHYMAL STEM CELLS REGULATE THE ACTIVATED COMPLEMENT C5 BY CLUSTERIN IN THE TREATMENT OF LUPUS NEPHRITIS

 H. Ma1, M. Guo1, L. Sun2, 1The First Affiliated Hospital Of Xinxiang Medical University, Weihui, China, 2The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China

 17:50 - 18:00

EPIDEMIOLOGY AND PRACTICE PATTERNS IN THE MANAGEMENT OF LUPUS NEPHRITIS IN AUSTRALIA

 

R. Phoon1, F. Brown2, T. Coates3, S. Ford4, A. Irish5, N. Isbel6, M. Thomas7, K. Wyburn8, 1Westmead Hospital, Westmead, Australia, 2Monash Medical Centre, Clayton, Australia, 3Royal Adelaide Hospital, Adelaide, Australia, 4St Vincent's Hospital, Melbourne, Australia, 5Fiona Stanley Hospital, Perth, Australia, 6Princess Alexandra Hospital, Brisbane, Australia, 7Royal Perth Hospital, Perth, Australia, 8Royal Prince Alfred Hospital, Sydney, Australia

 18:00 - 18:10

SYSTEMIC LUPUS ERYTHEMATOSUS IN THE INTENSIVE CARE UNIT: AN OBSERVATIONAL STUDY

  C. Aragon1, I. Ruiz-Ordoñez2, M. Gallego3, N. Gallego2, J. Diego-Bolaños2, M. Angélica-Guerra2, M. E. Ochoa2, M. Granados4, J. Quintana2, A. Suarez-Avellaneda2, G.J.

Tobón2, 1Universidad Icesi, Cali, Colombia, 2Fundación Valle del Lili, Universidad Icesi, Cali, Colombia, 3GIRAT: Grupo de Investigación en Reumatología, Autoinmunidad y Medicina Traslacional, Cali, Colombia, 4Fundacion valle del Lili, Santiago de cali, Colombia

 18:10 - 18:20

A NEW DIAGNOSTIC ALGORITHM FOR PATTERN-ORIENTED AUTOANTIBODY TESTING ACCORDING TO THE ICAP NOMENCLATURE: A PILOT STUDY

 

M. Infantino1, T. Carbone2, M. Manfredi3, V. Grossi3, A. Antico4, M.P. Panozzo4, I. Brusca5, M.G. Alessio6, G. Previtali6, S. Platzgummer7, L. Cinquanta8, G. Paura9, G. Deleonardi10, T. Teresa11, A. Radice12, C. Castiglione13, T. Imbastaro13, M. Fabris13, G. Pesce14, B. Porcelli15, L. Terzuoli15, M.C. Sorrentino16, M. Tampoia17, L. Abbracciavento17, D. Villalta18, M. Conte18, G. Barberio19, N. Gallo20, M. Benucci3, N. Bizzaro21, 1Ospedale San Giovanni di Dio, Azienda Usl Toscana Centro, Firenze, Italy, 2Ospedale San Carlo, Potenza, Italy, 3San Giovanni di Dio Hospital, Azienda USL Toscana Centro, Florence, Italy, 4Santorso, santorso, Italy, 5Ospedale Buccheri La Ferla FBF, Palermo, Italy, 6ASST Papa Giovanni XXIII, Bergamo, Italy, 7Ospedale Civile, Merano, Italy, 8Gruppo SYNLAB, Salerno, Italy, 9A.O.U San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy, 10Laboratorio Unico Metropolitano, Bologna, Italy, 11Ospedale G. Fracastoro, Verona, Italy, 12san carlo borromeo hospital, milan, Italy, 13P.O. Santo Spirito, Pescara, Italy, 14IRCCS Ospedale Policlinico San Martino, Genova, Italy, 15Policlinico S. Maria alle Scotte, AOU Senese, Siena, Italy, 16Dipartimento di Medicina di Laboratorio e Biotecnologie avanzate, Palermo, Italy, 17Azienda Ospedaliero-Universitaria, Policlinico di Bari, Bari, Italy, 18Presidio Ospedaliero S. Maria degli Angeli, Pordenone, Italy, 19UOC Medicina di Laboratorio Azienda ULSSn2, Treviso, Italy, 20University Hospital Padova, Padova, Italy, 21Azienda Sanitaria Universitaria Integrata di Udine, San Donà di Piave, Italy

 18:20 - 18:30

IL-1 FAMILY CYTOKINES AND RECEPTORS IN SCHNITZLER’S SYNDROME AND SYSTEMIC LUPUS

  P. Migliorini1, P. Italiani2, F. Pratesi1, I. Puxeddu1, D. Boraschi2, 1University of Pisa, Pisa, Italy, 2National Research Council, Napoli, Italy

 830

16:30 - 18:30

PS55 - GENETIC UNTIL PROVEN OTHERWISE BANQUETING

 16:30 - 16:50

FROM GENETIC TO EPIGENETIC: THE LUPUS-ENVIRONMENT INTERACTION

  C. Perricone, Università degli Studi di Perugia, 06129, Italy 16:50 - 17:10

ANTIPHOSPHOLIPID ANTIBODY CARRIERS: WHAT SHOULD AND SHOULD NOT BE DONE

  A. Tincani, , Italy

 17:10 - 17:20

GENOTYPE-PHENOTYPE CORRELATION OF FORKHEAD BOX P3 PROMOTER POLYMORPHISMS AND SUSCEPTIBILITY TO GENERALIZED VITILIGO IN GUJARAT, INDIAN POPULATION

  P. Giri1, M. Dwivedi1, S. Patel1, R. Begum2, 1Uka Tarsadia University, Bardoli, India, 2The Maharaja Sayajirao University of Baroda, Vadodara, India

 17:20 - 17:30

CAN HLA TYPE I AND II ALLELES PRESENCE BE ASSOCIATED WITH THE CLINICAL SPECTRUM OF CHIKV INFECTION?

 

D. Arsanios Martin1, J. Rueda2, A. Santos3, J.-I. Angarita3, E.-L. Saldarriaga3, V. Reyes4, D. Padilla3, S. Bernal-Macias3, S. Arias-Correal3, N. Muñoz3, J. Arias-Correal3, I. Peláez-Ballestas5, M. Cardiel6, J. Londono3, 1 Bogota, Colombia, 2Faculty of Medicine and Engineering, Universidad de La Sabana, Chia, Colombia, 3Grupo de Espondiloartropatías, Rheumatology Department, Universidad de La Sabana, Chia, Colombia, 4Hospital Militar Central, Bogotá, Colombia, Bogota, Colombia, 5Hospital General de México “Doctor Eduardo Liceaga”, Mexico, Mexico, 6Centro de Investigación Clínica de Morelia SC, Mexico, Mexico

 17:30 - 17:40

IL1RA EXPRESSION IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS: RELATIONSHIP WITH IL1RN VNTR GENOTYPES AND CLINICAL ACTIVITY.

 

C. Fuentes-Baez1, U. De La Cruz-Mosso2, B. Campos-López2, I. Parra Rojas3, S. Cerpa Cruz4, G. Sánchez Zuno5, S. Ramírez-Pérez2, J.F. Muñoz-Valle6, 1Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, 2Universidad de Guadalajara, Guadalajara Jalisco, Mexico, 3Universidad Autónoma de Guerrero, Chilpancingo, Mexico, 4Hospital Civil de Guadalajara “Fray Antonio Alcalde, Guadalajara, Mexico, 5 Guadalajara, Mexico, 6Universidad de Guadalajara, Guadalajara, Mexico

 17:40 - 17:50

STRATIFYING AUTOIMMUNE RHEUMATIC DISEASES INTO POLYAUTOIMMUNITY-BASED SUBGROUPS: INTRODUCING LATENT AND OVERT POLYAUTOIMMUNITY

 

M. Rojas1, A. Naranjo-Pulido2, A. Suarez2, M. Higuera2, D. Polanía2, M. Borras2, D. Monsalve2, Y. Pacheco2, Y. Acosta-Ampudia2, M. Rodríguez2, R. Mantilla2, C. Ramírez-Santana2, C.E. Toro Gutierrez3, G.J. Tobón4, J.-M. Anaya2, 1Universidad del Rosario, Bogotá D.C, Colombia, 2School of Medicine and Health Sciences, Bogotá D.C, Colombia, 3Centro de Referencia en Osteoporosis & Reumatología, Cali, Colombia, 4Fundación Valle del Lili, Universidad Icesi, Cali, Colombia

 17:50 - 18:00

ARE WE CONVERTING A GENETIC DISEASE INTO AN AUTOIMMUNE DISEASE WITH GENE CORRECTION STRATEGIES?

  K. Nagaraju, SUNY-Binghamton University, Johnson City, United States of America 

18:00 - 18:10

ENGINEERING THE MODULARITY OF SINGLE DOMAIN ANTIBODY TARGETING MHC CLASS II TO PROTECT AGAINST AUTOIMMUNE DISEASES

  N. Pishesha, Boston Children's Hospital, Cambridge, United States of America 18:10 - 18:20

SINGLE-CELL RNA-SEQ ANALYSIS REVEALS THE DIFFERENTIAL GENE EXPRESSION BY ARSENIC TRIOXIDE OF EARLY TREATMENT-NAÏVE RHEUMATOID ARTHRITIS PATIENTS

  C. Li1, Z. Zhang2, 1The first affiliated hospital of Harbin Medical University, Harbin, China, 2First Affiliated Hospital of Harbin Medical University, Harbin, China

 840

16:30 - 18:30

PS56 -T CELLS, T REGULATORY AND AUTOIMMUNITY

NIKOS SKALKOTAS

 Moderation: A. Malkova1, R. Giacomelli2, 1 , Russian Federation, 2University of L'Aquila, Department Of Applied Clinical Sciences And Biotechnology, Rheumatology Unit, School Of Medicine, L'Aquila, Italy

 16:30 - 16:40

EX-VIVO INCUBATION WITH FAS LIGAND SELECTIVELY DEPLETES ALLOREACTIVE T CELLS AND ANTIGEN PRESENTING CELLS – FROM HEMATOLOGICAL MALIGNANCIES TO AUTOIMMUNITY

  S. Yarkoni, cellect, KFAR SABA, Israel 16:40 - 16:50

EXTRACELLULAR VESICLES RELEASED FROM MESENCHYMAL STROMAL CELLS INDUCE TREG GENERATION AND PROTECT FROM IMMUNE-MEDIATED GLOMERULAR INJURY IN LUPUS NEPHRITIS

 

V. Cantaluppi1, G. Cappellano2, M. De Lena1, A. Chiocchetti1, M. Quaglia3, U. Dianzani1, G. Camussi4, 1Center for Traslational Research on Autoimmune and Allergic Disea se—CAAD, University of Eastern Piedmont, Novara, Italy, 2University of Piemonte Orientale UPO, Novara, Italy, 3 TORINO, Italy, 4University of Torino, Torino, Italy

 16:50 - 17:00

SKINT8, A NOVEL B7 FAMILY-RELATED MOLECULE, NEGATIVELY REGULATES T CELL RESPONSES

  L. Lai, Y. Lin, C. Cui, University of Connecticut, Storrs, United States of America 17:00 - 17:10

TH17 AND REGULATORY T CELLS AXIS IN TUNISIAN SYSTEMIC SCLEROSIS PATIENTS

  A. Gabsi1, A. Dlala2, R. Marrakshi1, 1Université de Tunis El Manar, Tunis, Tunisia, 2Faculty of Sciences of Tunis (Faculté des Sciences de Tunis), Tunis, Tunisia

 

17:10 - 17:20

CCR9 INTRINSIC SIGNALING IN DENDRITIC CELLS PROMOTE THE DIFFERENTIATION OF FOXP3+ REGULATORY CD4 T CELLS IN THE GUT

  M. Pathak, N. Halder, P. Padghan, G. Lal, National Centre for Cell Science, Pune, India 17:20 - 17:30

COMPARISON OF T FOLLICULAR HELPERS IN SARCOIDOSIS AND TUBERCULOSIS PATIENTS

 

A. Malkova1, I. Kudryavtsev2, M. Serebriakova3, Y. Zinchenko4, N. Basantsova2, A. Starshinova Aa4, P. Yablonskiy2, Y. Shoenfeld5, 1 , Russian Federation, 2St.Petersburg State University, St.Petersburg, Russian Federation, 3Institute of Experimental Medicine, St.Petersburg, Russian Federation, 4SPSU, Saint Petersburg, Russian Federation, 5Sheba Medical Center, Tel Aviv, Israel

 17:30 - 17:40

IMBALANCE OF T FOLLICULAR HELPER SUBSETS IN SARCOIDOSIS PATIENTS

 I. Kudryavtsev1, A. Starshinova1, U. Zinchenko1, N. Basantsova1, M. Serebriakova2, P. Yablonskiy1, 1St.Petersburg State University, St.Petersburg, Russian Federation, 2Institute of Experimental Medicine, St.Petersburg, Russian Federation

 17:40 - 17:50

REGULATORY T CELLS INDUCE ACTIVATION RATHER THAN SUPPRESSION OF HUMAN BASOPHILS

  M. Sharma1, M. Das1, E. Stephen-Victor1, S. Kaveri.2, J. Bayry1, 1Institut National de la Santé et de la Recherche Médicale-INSERM, Paris, France, 2cnrs, Paris, France

 17:50 - 18:00

REGULATORY T CELLS ARE LESS SENSITIVE TO GLUCOCORTICOID HORMONE INDUCED APOPTOSIS THAN CD4+ T CELLS

  T. Berki, T. Litvai, N. Balázs, L. Prenek, F. Boldizsar, University of Pecs, Pecs, Hungary 18:00 - 18:10

OXIDIZED PHOSPHOLIPIDS EXPOSING PHOSPHORYLCHOLINE INDUCE ACTIVATION OF MACROPHAGES AND T CELLS – IMPLICATIONS FOR ATHEROSCLEROSIS AND AUTOIMMUNE DISEASES

  M. Rahman, P. Gillgren, J. Steuer, J. Frostegard, Karolinska Institutet, Stockholm, Sweden 

85016:30 - 18:30

PS57 - NEW AUTOIMMUNE DISEASES MC3

  Moderation: R. Perricone1, Y. Levo2, 1 , Italy, 2Souraski Tel Aviv Medical Center, Tel Aviv, Medicine, Tel Aviv,, Israel

 16:30 - 16:50

AUTOIMMUNE MECHANISMS IN THE PATHOGENESIS OF ALZHEIMER´S DISEASE

  J. Alves, Fernando Fonseca Hospital, Amadora, Portugal 16:50 - 17:00

GLAUCOMA IS AN AUTOIMMUNE DISEASE?!

  Y. Levo1, O. Geyer2, 1Souraski Tel Aviv Medical Center, Tel Aviv, , Tel Aviv,, Israel, 2The Western Galilee Hospital in Nahariya, Nahariya, Israel

 17:00 - 17:10

UPDATE ON IGG4 AUTOIMMUNE DISEASES: NEW FAMILY MEMBERS

  I. Koneczny, Medical University of Vienna, Vienna, Austria 17:10 - 17:20

AUTOPSYCHOMICS: EXPLORING AUTOANTIBODY PROFILES IN PSYCHOTIC DISORDERS

 

A. Jernbom Falk1, D. Just2, A. Månberg3, C. Galletly4, O. Schubert4, P. Nilsson5, 1KTH/SciLifeLab, Solna, Sweden, 2Uppsala University, Uppsala, Sweden, 3Div. of Affinity Proteomics, Dept. of Protein Science, KTH Royal Institute of Technology, Stockholm, Sweden, 4University of Adelaide, Adelaide, Australia, 5KTH - Scilifelab, Stockholm, Sweden

 17:20 - 17:30

MYOCARDIUM DAMAGE AND ANTI-MITOCHONDRIAL ANTIBODY (AMA): CASE REPORT OF THREE NEWBORN SIBLING

  G. Previtali, M. Seghezzi, R. Ravasio, V. Moioli, M.G. Alessio, ASST Papa Giovanni XXIII, Bergamo, Italy

 17:30 - 17:40

NOVEL MATERNAL AUTOANTIBODIES IN AUTISM SPECTRUM DISORDER: POSSIBLE NEW PLAYERS FOR ETIOLOGY AND DIAGNOSIS

  R. Mazon Cabrera1, P. Vandormael2, V. Somers3, 1Hasselt University, hasselt, Belgium, 2UHasselt, Hasselt, Belgium, 3Hasselt University, Diepenbeek, Belgium

 17:40 - 17:50

AUTOIMMUNITY IN A COHORT OF CHILDREN WITH AICARDI-GOUTIÈRES SYNDROME

 

F. Zunica1, J. Galli2, L. Andreoli3, G. Gualdi4, M. Fredi5, S. Orcesi6, A. Tincani7, R. Badolato1, E. Fazzi2, M. Cattalini1, 1University of Brescia, Brescia, Italy, 2University of Brescia and ASST Spedali Civili di Brescia, Brescia, Italy, 3ASST Spedali Civili, Brescia; University of Brescia, Brescia, Italy, 4G. D'Annunzio University Chieti/Pescara, Chieti, Italy, 5ASST Spedali Civili, Brescia, Italy, 6Mondino National Neurological Institute, Pavia, Italy, 7 , Italy

 17:50 - 18:00

AUTOANTIBODIES AGAINST FCERIΑ OF DIFFERENT SUBCLASSES ARE FREQUENT AND ASSOCIATED WITH FEATURES OF CHRONIC SPONTANEOUS URTICARIA

  S. Altrichter, Charité – Universitätsmedizin Berlin, Berlin, Germany 18:00 - 18:10

IATROGENIC ALOGENOSIS AND ASIA SYNDROME SYMPTOMS INDUCED BY GLUTEAL BIOPOLYMER INJECTIONS: CASE-SERIES AND NARRATIVE REVIEW.

 G. Montealegre1, M.-A. Martínez-Ceballos2, R. Uribe1, A. Rojas-Villarraga2, 1Hospital de San José- Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, Colombia, 2Fundación Universitaria de Ciencias de la Salud-FUCS, Bogotá, Colombia

 860

16:30 - 18:30

PS58 - VITAMIN D AND AUTOIMMUNE DISEASES MC2

 Moderation: J. Damoiseaux1, S. Kivity2, 1Maastricht University Medical Center, Central Diagnostic Laboratory, Maastricht, Netherlands, 2Sheba Medical Center, Zabludowicz Center For Autoimmune Diseases, Tel-Hashomer, Israel

 16:30 - 16:50

NATURAL KILLER CELLS IN RELAPSING REMITTING MULTIPLE SCLEROSIS: RELATION WITH VITAMIN D3 AND PROGNOSTIC VALUE FOR DISEASE-ACTIVITY.

 M. Mimpen1, J. Damoiseaux2, J. Smolders3, R. Hupperts1, 1Maastricht University, Maastricht, Netherlands, 2Maastricht University Medical Center, Maastricht, Netherlands, 3Erasmus Medical Center, Rotterdam, Netherlands

 16:50 - 17:10

GENOTYPING OF VITAMIN D RECEPTOR POLYMORPHISMS IN A COHORT OF ANTI-DFS70 AUTOANTIBODIES POSITIVE SUBJECTS

 M.C. Padula1, T. Carbone1, V. Pafundi2, P. Leccese1, A.A. Padula1, G. Martelli3, S. D'Angelo1, 1Ospedale San Carlo, Potenza, Italy, 2Ospedale San carlo, Potenza, Italy, 3University of Basilicata, Potenza, Italy

 17:10 - 17:20

THE VITAMIN D RECEPTOR (VDR) FOK I POLYMORPHISM AND AUTOIMMUNITY IN A PORTUGUESE POPULATION: A RETROSPECTIVE CASE-CONTROL STUDY

 

A.M. Ferreira1, B. Leal1, S. Brás2, R. Samões1, E. Santos1, A.P. Sousa1, R. Faria1, B. Ferreira3, J. Correia1, C. Vasconcelos1, B. Silva1, T. Torres4, A. Marinho5, P. P Costa6, A. Martins Da Silva1, 1UMIB-ICBAS-UPorto, Porto, Portugal, 2Laboratório de Imunogenética, Porto, Portugal, 3Centro Hospitalar e Universitário do Porto, Hospital de Santo António (CHUP-HSA), Porto, Portugal, 4Centro Hospitalar e Universitário do Porto, Hospital de Santo António (CHUP-HSA), Portugal, Portugal, 5Hospital de Santo António, Porto, Portugal, 6Instituto Nacional de Saúde Dr. Ricardo Jorge, Porto, Portugal

 17:20 - ACCURATELY ASSESS VITAMIN D STATUS IN PATIENTS WITH SYSTEMIC

17:30 LUPUS ERYTHEMATOSUS  S.-Y. Guan, F. Pan, Anhui Medical University, Hefei, China 17:30 - 17:40

INTRIGUING INTERPLAY BETWEEN VITAMIN D, INF-GAMMA, AND E2 IN FEMALE SLE PATIENTS WITH INACTIVE DISEASE.

 V. Kokić Maleš1, D. Martinovic Kaliterna2, M. Radic3, D. Perkovic3, M. Cvek3, V. Capkun3, 1Spinciceva 2, Split, Croatia, 2Clinical Hospital Centre Split, Split, Croatia, 3Clinical Hospital Centre Split, School od Medicine, Split, Croatia

 17:40 - 17:50

ASSESSING VITAMIN D LEVELS IN AN ANTI-DFS70 POSITIVE POPULATION: NEW INSIGHTS EMERGING

 

T. Carbone1, V. Pafundi2, N. Bizzaro3, M. Infantino4, M.C. Padula1, A. Padula1, S. D'Angelo1, 1Ospedale San Carlo, Potenza, Italy, 2Ospedale San carlo, Potenza, Italy, 3Azienda Sanitaria Universitaria Integrata di Udine, San Donà di Piave, Italy, 4Ospedale San Giovanni di Dio, Azienda Usl Toscana Centro, Firenze, Italy

 17:50 - 18:00

REVEALING ABERRANT GLYCOSYLATION IN TUMORS BY NATURAL HUMAN ANTIBODIES

 

B. Kotlan1, S. Horvath1, K. Eles1, V. Plotar1, K. Czirbesz1, L. Fulop1, E. Farkas1, M. Ujhelyi1, A. Savolt1, A. Szollar1, M. Blank2, Y. Shoenfeld3, M. Kasler4, G. Liszkay1, 1National Institute of Oncology, Budapest, Hungary, 2Sheba Medical Center, Tel-Hashomer, Israel, 3Sheba Medical Center, Tel Aviv, Israel, 4Ministry of Human Capacities, Budapest, Hungary

 870

16:30 - 18:30

PS59 - JUVENILE AUTOIMMUNE DISEASES KOKKALI

 

Moderation: T. Avcin1, Y. Uziel2, 1Children's Hospital, University Medical Center Ljubljana, Department Of Allergology, Rheumatology And Clinical Immunology, Ljubljana, Slovenia, 2Meir Medical Center, Kfar Saba, Israel, Pediatric Rheumatology Unit, Department Of Pediatrics, Kfar Saba, Israel

 16:30 - 16:50

DEVELOPMENT OF IMMUNE SYSTEM AND ALTERNATIVE AUTOIMMUNE RESPONSES IN INFANTS

  T. Avcin, Children's Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia 16:50 - 17:10

JUVENILE IDIOPATHIC ARTHRITIS- A BREAKING BORDER DISEASE

  Y. Uziel, Meir Medical Center, Kfar Saba, Israel, Kfar Saba, Israel

 17:10 - 17:20

EFFICACY OF TOCILIZUMAB ADDED TO STEROIDS IN NAÏVE TAKAYASU ARTERITIS PATIENTS: FRENCH PROSPECTIVE MULTICENTER OPEN-LABELLED TRIAL.

  A. Mekinian, O. Fain, Hopital saint-antoine, Paris, France 17:20 - 17:30

THERAPEUTIC MANAGEMENT OF JUVENILE IDIOPATHIC ARTHRITIS WITH TOCILIZUMAB IN CENTRAL ASIA: PRELIMINARY DATA FROM A SINGLE TERTIARY CENTER EXPERIENCE IN KAZAKHSTAN.

 D. Poddighe1, Z. Mukusheva2, M. Assylbekova2, 1Nazarbayev University School of Medicine, Nur-Sultan City, Kazakhstan, 2UMC Republican Diagnostic Center, Nursultan City, Kazakhstan

 17:30 - 17:40

GENETIC ANCESTRY AND ITS CONTRIBUTION TO COMPLEX TRAITS IN CHILDHOOD-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS

 F. Barbosa1, L. De Oliveira2, N. Sinicato2, V. Gil-Da-Silva-Lopes3, R. Marini3, S. Appenzeller2, 1USP-RP, Ribeirão Preto, Brazil, 2University of Campinas, Campinas, Brazil, 3Unicamp, Campinas, Brazil

 17:40 - 17:50

LONGITUDINAL EVALUATION OF EXECUTIVE FUNCTIONS IN PATIENTS WITH CHILDHOOD-ONSET SYSTEMIC LUPUS ERYTHEMATOSU

  J. De Amorim1, C. Elorza2, R. Marini3, S. Appenzeller1, 1University of Campinas, Campinas, Brazil, 2UNICAMP, Campinas, Brazil, 3Unicamp, Campinas, Brazil

 17:50 - 18:00

DIAGNOSTIC AND PROGNOSTIC VALUES OF MUSCLE ISG15 MUSCULAR EXPRESSION IN JUVENILE INFLAMMATORY MYOPATHIES

 

C. Hou1, C. Durrleman1, B. Periou1, C. Barnerias2, C. Bodemer2, I. Desguerre2, P. Quartier2, I. Melki3, M. Rodero4, J.-L. Charuel3, B. Bader-Meunier2, F.J. Authier5, C. Gitiaux5, 1INSERM, Creteil, France, 2APHP Necker Hospital, PARIS, France, 3APHP Robert Debré Hospital, PARIS, France, 4INSERM, PARIS, France, 5Paris Est Creteil University, Creteil, France

 18:00 - 18:10

IGG4 RELATED DISEASE IN CHILDREN: A SINGLE CENTRE EXPERIENCE FROM NORTH-WEST INDIA

  A. Rawat, R. Pilania, A. Gupta, D. Suri, V. Pandiarajan, A. Jindal, R. Nada, S. Singh, Postgraduate Institute of Medical Education and Research, Chandigarh, India

 18:10 - 18:20

ARE VACCINATIONS IN CHILDREN TREATED WITH ANTI-CYTOKINE THERAPY SAFE AND IMMUNOGENIC?

  N. Toplak1, Y. Uziel2, 1Ljubljana University Medical Centre, Ljubljana, Slovenia, 2Meir

Medical Center, Kfar Saba, Israel, Kfar Saba, Israel 18:20 - 18:30

STUDY OF COMMON BACTERIAL AND FUNGAL PATHOGENS IN CHILDREN WITH HEMATOLOGICAL MALIGNANCIES DURING FEBRILE NEUTROPENIA: SINGLE CENTER EGYPTIAN STUDY.

  M. El-Gamasy, Faculty of Medicine,Tanta University,Egypt, 1880, Egypt 

87516:30 - 18:30

PS60 - THE 3RD GREEK ISRAEL AUTOIMMUNITY\RHEUMATOLOGY MEETING

CONFERENCE ROOM 1

 16:30 - 16:40

ACUTE ONSET OF PSORIATIC SPONDYLOARTHRITIS AS A NEW MANIFESTATION OF POST-STREPTOCOCCAL REACTIVE ARTHRITIS: A CASE SERIES

 A. Dagan1, S. Dahan1, O. Shovman2, P. Langevitz2, T. Hellou1, A. Shemer2, Y. Shoenfeld3, 1Assuta Ashdod medical center, Ashdod, Israel, 2Sheba Medical Center, Tel-Hashomer, Israel, 3Sheba Medical Center, Tel Aviv, Israel

 16:40 - 16:50

TUBULOINTERSTITIAL NEPHRITIS AND UVEITIS SYNDROME: POSSIBLE ASSOCIATION WITH SYSTEMIC LUPUS ERYTHEMATOSUS

  T. Kolitz1, G. Zandman-Goddard1, S. Shiber2, A. Biro1, 1wolfson, holon, Israel, 2rabin medical center , Petach tikva, Israel

 16:50 - 17:00

A SUCCESSFUL PREGNANCY WITH ANAKINRA EXPOSURE IN RECURRENT PERICARDITIS

  S. Dahan, A. Dagan, Assuta Ashdod medical center, Ashdod, Israel 17:00 - 17:10

RESISTANT EOSINOPHILIC FASCIITIS: CLINICAL EXPERIENCE WITH BIOLOGIC TREATMENT: REPORT OF 3 CASES AND REVIEW OF THE LITERATURE

  D. Erez, Meir Medical Center , Kfar Saba, Israel 17:10 - 17:20

DEVELOPMENT OF THE NOVEL INHIBITOR OF THE LEUKOCYTE TRANSMIGRATION AS A DRUG CANDIDATE FOR THE UNIVERSAL TREATMENT OF AUTO-IMMUNE DISEASES

  A. Gruzman, Bar-Ilan University, Ramat-Gan, Israel 17:20 -

THE DNA DAMAGE RESPONSE AND REPAIR (DDR/R) NETWORK IN SYSTEMIC

17:30 AUTOIMMUNE DISORDERS

 

M. Pappa1, N. Vlachogiannis2, A. Argyriou2, P. Ntouros2, M. Tektonidou3, V. Souliotis4, P. Sfikakis1, 1National and Kapodistrian University of Athens, School of Medicine, Athens, Greece, 2First Department of Propaedeutic Internal Medicine, Athens, Greece, 3Medical School, National and Kapodistrrian University of Athens, Athens, Greece, 4Institute of Chemical Biology, Athens, Greece