NEUROPROTECTIVE SIGNALING THROUGH METABOTROPIC GLUTAMATE RECEPTOR 1
UC Davis/NIH NeuroMab Facility · Glutamate receptor 1, Ionotropic AMPA-selective glutamate...
1
Anti-GluA1/GluR1 glutamate receptor, NeuroMab clone N355/1 Immunogen: Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 (also known as Glutamate receptor 1, Ionotropic AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, GLUH1 and Gria1, accession number P19490) Mouse: 99% identity (388/389 amino acids identical) Human: 97% identity (379/389 amino acids identical) 100% identity between Flip and Flop isoforms >50% identity with GluA2/GluR2, GluA3/GluR3 and GluA4/GluR4 Monoclonal antibody info: Mouse strain: Balb/C Myeloma cell: SP2/0 Mouse Ig Isotype: IgG1 NeuroMab Applications: Immunoblot, Immunocytochemistry and Immunohistochemistry Species Reactivity: rat, mouse Does not cross-react with GluR2 MW: 100 kDa Top left: immunofluorescence staining of 14 DIV cultured rat cortical neuron with N355/1. Image courtesy of Brad Elmer and Kim McAllister (UCD). Top right: adult rat brain membrane immunoblot Middle: transfected cell immunoblot: extracts of COS cells transiently transfected with untagged GluR1, GluR2 or Kv2.1 plasmid and probed with N355/1 (left), L21/32 (middle) or N52A/42 (right) TC supe. Adult rat hippocampus immunohistochemistry UC Davis/NIH NeuroMab Facility Department of Physiology and Membrane Biology, UC Davis, Davis CA 95616 http://neuromab.ucdavis.edu [email protected]u © 2020 The Regents of the University of California All Rights Reserved Available as TC supe (RRID: AB_2315839) & Pure IgG (RRID: AB_2315840)
Transcript of UC Davis/NIH NeuroMab Facility · Glutamate receptor 1, Ionotropic AMPA-selective glutamate...
Anti-GluA1/GluR1 glutamate receptor, NeuroMab clone N355/1
Immunogen: Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 (also known as
Glutamate receptor 1, Ionotropic AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, GLUH1 and Gria1, accession number P19490)
Mouse: 99% identity (388/389 amino acids identical) Human: 97% identity (379/389 amino acids identical) 100% identity between Flip and Flop isoforms >50% identity with GluA2/GluR2, GluA3/GluR3 and
GluA4/GluR4
Monoclonal antibody info: Mouse strain: Balb/C Myeloma cell: SP2/0 Mouse Ig Isotype: IgG1
NeuroMab Applications: Immunoblot, Immunocytochemistry and Immunohistochemistry
Species Reactivity: rat, mouse
Does not cross-react with GluR2
MW: 100 kDa
Top left: immunofluorescence staining of 14 DIV cultured rat cortical neuron with N355/1. Image courtesy of Brad Elmer and Kim McAllister (UCD).
Top right: adult rat brain membrane immunoblot
Middle: transfected cell immunoblot: extracts of COS cells transiently transfected with untagged GluR1, GluR2 or Kv2.1 plasmid and probed with N355/1 (left), L21/32 (middle) or N52A/42 (right) TC supe.
Adult rat hippocampus immunohistochemistry
UC Davis/NIH NeuroMab Facility Department of Physiology and Membrane Biology, UC Davis, Davis CA 95616http://neuromab.ucdavis.edu [email protected]
© 2020 The Regents of the University of CaliforniaAll Rights Reserved
Available as TC supe (RRID: AB_2315839) & Pure IgG (RRID: AB_2315840)
![Reduced aggression in AMPA-type glutamate receptor GluR …0].pdf · Reduced aggression in AMPA-type glutamate receptor GluR-A subunit-deficient mice ... conditioning responses ...](https://static.fdocuments.net/doc/165x107/5aa910cb7f8b9a72188c6780/reduced-aggression-in-ampa-type-glutamate-receptor-glur-0pdfreduced-aggression.jpg)
