Traumatic lesions.

Clinic, diagnostics, treatment.

Oral ulcers

How to diagnose?

What is an ulcer?

A mouth or oral ulcer   is an open sore in the mouth, or rarely a break in the mucous membrane or the epithelium on the lips or surrounding the mouth. 

Epidemiology and frequency

Mouth ulcer is a very common oral lesion. Epidemiological studies show an average prevalence between 15% and 30%. Mouth ulcers tend to be more common in women and those under 45. 

The frequency of mouth ulcers varies from fewer than 4 episodes per year (85% of all cases) to more than one episode per month (10% of all cases) including people suffering from continuous recurrent aphthous stomatitis

What cause ulcers?

Trauma (physical injuries) Chemical injuries Smoking Infection - viral - bacterial - fungal - protozoans Immunodeficiency Autoimmunity Allergy Dietary

Tools for diagnosis:

History Examination Further investigation Additional diagnostic methods – biopsy

Further investigation – questions you should ask: How long have you had that ulcer? How many ulcers do you have? Is it painful? Can you relate them to any trauma, hot food

or another factors? Is it the first time or you had them before? Where are they located in the mouth? Do they start as ulcer or as vesicle/bulla? Do you get them anywhere else on the body?

 Step by step guide to performing an oral cavity examination

Things you need to look for:

Site Number Size Shape Base Edge

Differential diagnostic, based on history How long have you had the ulcer?

Long time – chronic1. Chronic trauma (single, can identify the cause,

and should improve after removal) 2. Malignancy (single, painless)3. TB (single ulcer in the tongue/palate,

associated symptoms – chronic cough)4. Mucous membrane pemphigoid (multiple ulcers

affect mainly gingiva, blood filled blisters) 5. Primary or tetriary syphilis

Recent – acute

1. Acute trauma (single, can identify the cause, and should improve after removal)

2. Viral infection (multiple, associated symptoms – fever)

3. Immune mediated disease (Erythema multiforme, RAS)

How many ulcers do you have? Single

1. Traumatic

2. Primary or tetriary syphilis

3. TB

4. Malignancy Multiple

1. Viral infection

2. Immune mediated disease

Is it painful?

Yes

Acute causes (trauma, viral, immune mediate) No

Chronic causes (trauma, TB)

Can you relate them to trauma or hot food? Yes

1. Confirm traumatic ulcer

2. Remove the cause

3. Review after 1 week No

Look for other causes

Do you get them anywhere else on the body? No

Think or oral conditions Yes – where?

1. Skin – mucocutanous disease (lichen planus, pemphigus)

Traumatic lesions

Mechanical trauma (acute or chronic) Chemical injury (acid, alcali) Physical injury (thermal injury, electrical

injury)

Mechanical trauma

Can be:

1. Acute

2. Chronic

And caused by:

1. A sharp edge of a tooth

2. Accidental biting3. Sharp, abrasive,or

excessively salty food 4.  Poorly fitting dentures 5. Dental braces 6. Trauma from a tooth

brush 7. Patients bad habits

Dental braces

Acute trauma

Single, can identify the cause should improve after

removal

Traumatic ulcers:

Clinical featuresof traumatic ulcers:  •They are clinically diverse, but usually appear as a single,

painful ulcer with a smooth red or whitish-yellow surface and a thin erythematous halo.

•They are usually soft on palpation, and heal without scarring within 6–10 days, spontaneously or after removal of the cause.

•However, chronic traumatic ulcers may clinically mimic a carcinoma.

•The tongue, lip, and buccal mucosa are the sites of predilection. •The diagnosis is based on the history and clinical features. •However, if an ulcer persists over 10–12 days a biopsy must be

taken to rule out cancer.

Treatment

1. Removing factors, caused trauma

2. Good hygiene of oral cavity

3. Antiseptic for 7-10 days

4. Analgetics if it is necessary

5. Topical steroids may be used for a short time.

6. Biopsy

Leukoplakia

Etiology: - trauma from habitual biting, dental appliances- tobacco use- alcohol consumption -oral sepsis- local irritation -syphilis -vitamin deficiency- endocrine disturbances -dental galvanism -actinic radiation (in the case of lip involvement).

Symptoms - painless, fuzzy white patches on the side of the tongue or cheeks.

Clinic

- located on the tongue, mandibular alveolar ridge and buccal mucosa in ~50%.- palate, maxillary alveolar ridge, lower lip, floor of the mouth and the retromolar regions are somewhat less frequently involved.- may vary from nonpalpable, faintly translucent white areas to thick, fissured, papillomatous, indurated lesions.- surface is often wrinkled or shriveled in appearance and may feel rough on palpation.- color may be white, gray, yellowish-white, or even brownish-gray in patients with heavy tobacco use.

Physical:- lesion cannot be wiped away with a gauze

Differential diagnosis:

1. Candidiasis and aspirin burn - can be wiped away with a gauze

2. Erythroplakia (a red plaque that does not rub off), is a dysplastic lesion (or worse) in 90 percent of cases.

Treatment

Treat dental causes such as rough teeth, irregular denture surface, or fillings as soon as possible.

Stopping tobacco or/and alcohol. Removal of leukoplakic patches with

using a scalpel, a laser or an extremely cold probe that freezes and destroys cancer cells (cryoprobe).

Chemical injures:

Chemicals such as aspirin or alcohol

 that are held or that come in contact with the oral mucosa may cause tissues to become necrotic and slough off creating an ulcerated surface.

Treatment:

1. Wash a mouth with lot of water

2. Analgetics (for 3-5 days )

3. Antiseptics ( for 7 – 10 days)

4. Keratolytics (after 5-7 days)

5. Keratoplastics (after 7-10 days)

Physical injures:

Electric Burns to the Mouth -are most commonly caused when a child bites into a cord, touches the male ends of a "live" but improperly connected cord, or sucks on the female end of an extension cord that is plugged into the wall. The vast majority of the patients is younger than three years.

Treatment:

1. Conservative Antiseptics Antibiotics Analgetic

2. Surgical (after the healing was completed and after the degree of functional and/or aesthetic deformity was established (usually 6 months post-injury)).

Stomatitis 

DescriptionStomatitis is an inflammation of the lining of any of the soft-tissue

structures of the mouth. Stomatitis is usually a painful condition, associated with redness, swelling, and occasional bleeding from the affected area. Bad breath (halitosis) may also accompany the condition. Stomatitis affects all age groups, from the infant to the elderly.

DefinitionInflammation of the mucous lining of any of the structures in the

mouth, which may involve the cheeks, gums, tongue, lips, and roof or floor of the mouth. The word "stomatitis" literally means inflammation of the mouth. The inflammation can be caused by conditions in the mouth itself, such as poor oral hygiene, poorly fitted dentures, or from mouth burns from hot food or drinks, or by conditions that affect the entire body, such as medications, allergic reactions, or infections.

Herpetic stomatitis

Herpetic stomatitis is a viral infection of the mouth that causes ulcers and inflammation. These mouth ulcers are not the same as canker sores, which are caused by a different virus.

Symptoms:

Blisters in the mouth, often on the tongue, cheeks, palate, gums, and a border between the lip (red colored) and the normal skin next to it

Decrease in food intake, even if the patient is hungry

Difficulty swallowing (dysphagia) Drooling Fever (often as high as 104

°Fahrenheit) may occur 1 - 2 days before blisters and ulcers appear

Irritability Pain in mouth Swollen gums Ulcers in the mouth, often on the

tongue or cheeks -- these form after the blisters pop

Causes

Herpetic stomatitis is a contagious viral illness caused by Herpes virus hominis (also herpes simplex virus, HSV). It is seen mainly in young children. This condition is probably a child's first exposure to the herpes virus.

An adult member of the family may have a cold sore at the time the child develops herpetic stomatitis. More likely, no source for the infection will be discovered.

Differential diagnostics:

Streptococcal pharyngitis –does not involve the lips or perioral tissues and vesicles do not precede the ulcers

Erythema multiforme – ulcers are larger, usually without a vesicular stage and are less likely to affect the gingiva.

Aphthous stomatitis – the multiply lesions, palatal and gingival location are indicative to herpesvirus infection. Additionally, aphthae usually localized only on nonceratinized mucoza, such as the floor of the mouth, alveolar mucosa and buccal mucosae.

Treatment:

Good oral hygiene Acyclovir family of antiviral medications – non

later than 48 hours! Analgetic ( or oral topical anesthetic ) Diet (no hot or pepper food) Antiseptics

Aphthous Ulcers

Of all the type of nontraumatic ulcaration that affect oral mucosa that is the most common.

Aphthous ulcers are also known as canker sores. They are painful, temporary sores that may occur anywhere in the mouth. Usually, they show up in several places:

On the inside of the lips Inside the cheeks On the tongue At the base of the gums

Canker sores on tongue:

Etiology:

1.  Immune system disorders2. Other conditions cause similar sores: Blood and immune system diseases,

including HIV Vitamin and mineral deficiencies Allergies

Trauma Crohn's disease Lupus

Clinical features: Three forms of aphthous ulcers have been recognized:

minor, major and herpetiform.

§  Major Ulcerations (> 0,5cm)—10% of lesions o   extremely painful (odynophagia)... typically heal with scar formation o   Appearance- deeply cratered ulcers o   Duration-    > 1 month for healing. o   Location- posterior oral cavity. 0 Number – 1- 10 o   NOTE- THINK OF HIV DISEASE PROGRESSION OR IMMUNOSUPPRESION §  Minor Ulceration (1-5 mm)—85% of lesions o   painful… heal without scar formation o   Duration- 7-10 days o   Location- anterior oral cavity 0 Number – 1-5 §  Herpetiform Ulceration (1-3mm lesions that form clusters)—5% of lesions. o   Sxs- as above (but more severe) 0 Number – 10-100 o   Locational – any intraoral site

Minor ulcers:

Are the most commonly encountered form

Single, painful oval ulcer less than 0,6 mm, covered by a yellow fibrinous membrane

Last 7 to 10 days Periods of freedom

from disease – 2-3 weeks to year

Major ulcers:

Lesions are larger: more than 10 mm

More painful Persist longer that minor

aphthae One ulcer disappears,

another one starts Healing generally occurs in

6 weeks and longer Chronic stress, common

disease can cause

Herpetiform ulcers

Recurrent crops of small ulcers

Healing generally occurs in 1 to 2 weeks

Not preceded by vesicle and exhibit no virus-infected cells

Treatment:

Oral hygiene Avoiding spicy food Oral rising with sodium bicarbonate Analgesics Antiseptics Anti – inflammatory agents Antimicrobial and corticosteroids

Noma

also known as cancrum oris or gangrenous stomatitis, is a gangrenous disease leading to tissue destruction of the face, especially the mouth and cheek.

Noma (derived from the Greek "nomein" meaning "to devour") is a devastating gangrenous disease which attacks children, quickly destroying their mouth, nose, and face, and which can prove fatal after just a few weeks. Noma, also known as cancrum oris, seems to start on the gum and extends outwards to the cheeks and lips.

NOMA FACTS

NOMA FACTS Mainly attacks children 2-14

years old. Africa accounts for the

majority of the cases. The World Health

Organization estimates that 100,000 children contract noma every year.

Without treatment, the mortality rate is 70-90%.

Most victims starve to death because their jaw muscles are literally eaten away and they cannot chew; others die as the infection spreads.

key players in the process :

 Fusobacterium necrophorum Prevotella intermedia  Borrelia vincentii Porphyromonas gingivalis Tannerella forsynthesis Treponema denticola Staphylococcus aureus

The reported predisposing factors include: The reported predisposing factors include: Malnutrition or dehydration Poor oral hygiene Poor sanitation Unsafe drinking water Proximity to unkempt livestock Recent illness Malignancy An immunodeficiency disorder, including AIDS

Symptoms:

The early features of noma include soreness of the mouth, a swollen tender cheek, a foul-smelling purulent oral discharge, fetid odor in the mouth of the affected child, swelling of the regional lymph nodes, anorexia, grayish-black discoloration of the skin in the affected area. The long-term effects of Noma depend largely on the anatomic

sites of the lesion, the extent and severity of tissue destruction and the stage of development of the dentition and facial skeleton prior to onset of the disease.

Treatment:

The progression of the disease can be halted with the use of antibiotics and improved nutrition;

however, its physical effects are permanent and may require reconstructive plastic surgery to repair.

Reconstruction is usually very challenging and it should be delayed until full recovery (usually about one year following initial intervention)