Tissues, Glands & Membranes

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    Tissues Glands &Membranes

    Neriza G. Mamasabulod, RN, MAN

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    Tissue

    A tissue is a group of cells with

    similar structure and function, as

    well as the extracellular

    substances located between the

    cells.

    HISTOLOGY is the study of

    tissues

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    Functions of the Epithelia

    Protection-ex. Epithelium of the oral

    cavity, which protect the underlyingstructures from abrasion

    Acting as barriers-prevents entry oftoxic molecules or microorganisms

    into the body Passage of substances-ex. O2 &

    CO2 exchanged through the lungs

    Secretion-ex. Sweat glands &mucous glands

    Absorption of substances-ex.Epithelial cells of the intestine whichabsorbs digested food molecules,

    vitamins & ions

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    Types of Tissue

    Epithelial tissue-covers surfaces,lines cavities & forms glands.

    Connective tissue-supports &forms the framework of all parts

    of the body.

    Muscle tissue-contracts &

    produces movement.

    Nervous tissue-conducts nerveimpulses.

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    Epithelial Tissue- covers surfaces, usually

    has a basement

    membrane, has littleextracellular material, and

    has no blood

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    Classification ofEpithelia

    Simple epitheliumhas one layerof cells, whereas stratefied

    epithelium has more than one

    Pseudostratified columnarepitheliumis simple epitheliumthat appears to have two or more

    cell layers Transitional epitheliumis

    stratified epithelium that can be

    greatly stretched.

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    Typesof

    Epithelium

    (a)Simple

    Squamous

    Epithelium-

    single layerof thin, flat

    cells

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    (b) Simple Cuboidal Epithelium- single layer of cubelike cells

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    (c) Simple Columnar Epithelium- singlela er of tall thin cells

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    (d) PseudostratifiedColumnar Epithelium-prefix pseudo means

    false, appears to bestratified but not.

    Consist of one layer of

    cells attached to a

    basement membrane.

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    (e) StratifiedSquamous

    Epithelium-

    thick,consists

    of many

    layer

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    (f)Transitional

    Epithelium-greatly

    stretch

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    Structural and FunctionalRelationships

    Simple epitheliumis involved withdiffusion, secretion, or absorption.

    Stratified epitheliumserves a

    protective role. Squamous cellsfunction in diffusionor filtration. Cuboidal or columnarcells, which contain more organelles,

    secrete or absorb. A smooth free surface reduces

    friction. Microvilliincrease surfacearea, and ciliamove materials over

    the cell surface.

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    Cont

    Desmosomesmechanically bindcells together, tight junction form

    a permeability barrier, and gap

    junctions allow intercellularcommunication.

    Hemidesmosomesmechanically

    bind cells to the basementmembranes.

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    Glands

    A gland is a single cell or a

    multicellular structure that

    secretes

    Exocrine glands have ducts, and

    endocrine glands do not

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    CONNECTIVE TISSUE Connective tissue holds cell and

    tissues together.

    It has an extracellular matrix

    consisting of protein fibers, ground

    substance, and fluid Collagen fibers are flexible but resist

    stretching, reticular fibers form a fiber

    network, and elastic fibers recoil Blast cells form the matrix, cyte cells

    maintain it and clast cells break it

    down

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    Functions of Connective Tissue Connective tissues enclose and separate-ex.

    Separate muscles, arteries, veins & nerves fromone another.

    Connect tissues to one another-ex. Tendons arestrong cables or bands that attach muscle tobones & ligaments.

    Support and movement-ex. Skeleton providesrigid support for the body, semirigid cartilagesupports structures such as the nose, ears &surfaces of joints.

    Storing-adipose tissue (fat) stores high-energymolecules.

    Cushion and insulation-adipose tissue (fats)

    protects the tissues it surrounds & insulate toconserve heat

    Transport of blood-such as gases, nutrients,hormones, enzymes & cells of immune system.

    Protection from microorganisms-such as toxins

    Cl ifi i f

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    Classification ofConnective Tissue

    1. Embryonic connective tissue givesrise to six major categories ofconnective tissue

    2. Loose, or areolar, connective

    tissueis the loose packingmaterial of the body, which fills thespaces between the organs andholds them in place.

    3. Adipose, or fat, tissuefunctionsto store energy. Adipose tissuealso pads and protects parts of thebody and acts as as thermalinsulator.

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    4.Dense connective tissueconsists of

    matrix containing densely packed

    collage fibers (tendons, ligaments, anddermis of the skin)or of matrix containing

    densely packed elastic fibers (elastic

    ligaments and in the walls of arteries).

    5. Cartilageprovides support and is foundin structures such the costal cartilages,

    disks between vertebrae, and external

    ear.

    6. Bonehas a mineralized matrix and formsmost of the skeletons of the body.

    7. Bloodhas a liquid matrix and is found inblood vessels.

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    (d) Dense Elastic Connective Tissue

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    -Is the most abundant type of cartilage& has man functions.

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    - Hard Connective Tissue

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    Muscle Tissue

    1. Muscle tissue is specialized to

    contract or shorten, making

    movement possible.

    2. The three types of muscle

    tissue are skeletal, cardiac and

    smooth muscles.

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    Nervous Tissue

    1. Forms the brain, spinal cord

    and nerves.

    2. Nervous Tissue is specialized to

    conduct action potentials

    (electrical signals)

    3. Neurons conduct action

    potentials, and neurogliasupport the neurons

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    Membranes: Mucous

    MembranesMucous Membranes line cavities

    that open to the outside of the

    body ( digestive, respiratory,excretory, and reproductive

    tracts). They contain glands and

    secrete mucus.

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    Membranes: SerousMembranes

    Serous membranes line trunk

    cavities that do not open to the

    outside of the body (pleural,pericardial, and peritoneal

    cavities). They do not contain

    glands but do secrete serousfluid.

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    Other Membranes

    Other membranes include the

    cutaneous membrane (skin)

    synovial membranes (line joint

    cavities) and periosteum ( aroundthe bone)

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    Inflammation

    1. The function of the inflammatory

    response is to isolate and

    destroy harmful agents.

    2. The inflammatory response

    produces five symptoms:

    redness, heat, swelling

    (edema), pain, and disturbanceof function.

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    Chronic Inflammation

    Chronic inflammation results

    when the agent causing injury is

    not removed or something else

    interferes with the healingprocess.

    1 A splinter in the skin

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    1. A splinter in the skincause damage &introduces bacteria.Mediators of

    inflammation arereleased.

    2. Mediators ofinflammation causecapillaries to dilatecausing, the skin tobecome red.

    3. WBC (ex. neutrophils &macrophages) leave

    the dilated bloodvessels & move to thesite of bacterial infx.Where they begin tophagocyte bacteria &

    other debris.

    Tissue Repair

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    Tissue Repair1. Tissue repair is the substitution of

    viable cells for dead cells. Labile cells

    divide throughout life and can undergo

    regeneration. Stable cells do not

    ordinarily divide but can regenerate if

    necessary. Permanent cells have littleor no ability to divide if killed repair is

    by replacement.

    2. Tissue repair involves clot formation,

    inflammation, formation of granulationtissue, and regeneration or

    replacement of tissues in severe

    wounds, wound contracture can occur.

    1. Fresh wound

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    1. Fresh woundcuts theepithelium(epidermis &dermis) & a cloyis formed.

    2. Approx. 1 wk.after the injury,a scab ispresent &epithelium isgrowing into the

    wound.3. Approx. 2 wks.

    the epitheliumhas growncompletely intothe wound.

    4. Approx. 1 monththe hascompletelyclosed w/c isreplaced by anew connectivetissue.

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    Tissues & Aging

    Cells divide more slowly as

    people age. Injuries heal more

    slowly.

    Extracellular matrix containing

    collagen and elastic fibers

    become les flexible and less

    elastic. Consequently, skinwrinkles elasticity in arteries is

    reduced, and bones break more

    easily.

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    Thats all folks !!!