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Signs & Symptoms of Hypothyroidism

Nonspecific• Weight gain• Fatigue• Poor concentration• Depression• Diffuse muscle pain• Menstrual irregularities

Specific• Constipation• Cold intolerance• Dry skin• Proximal muscle weakness• Hair thinning/loss

Physical Exam May Reveal:

• Goiter• Delayed deep tendon reflex

(DTR)• Thin/brittle hair• Dry skin• Peripheral edema

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Alternate causes of hypothyroid-like symptoms (Gaitonde et al, 2012)

• Adrenal insufficiency (rare)• Anemia and/or iron, b12

deficiency• Chronic kidney disease• Depression, anxiety disorder• Liver disease• Obstructive sleep apnea• Viral infection (e.g. mono,

Lyme’s, HIV)• Vitamin D deficiency

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Common Symptoms of Hyperthyroidism

• Heart palpitations• Tachycardia/atrial fibrillation,

tremor, muscle weakness• Nervousness• Sweating• Hyperdefecation• Heat intolerance• Oligomenorrhea• Weight loss despite increased

appetite• Tired but have a hard time sleeping• Drooping eyelids/stare• Exopthalamus

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