Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy

outcomes

by Marie Scully, Mari Thomas, Mary Underwood, Henry Watson, Katherine Langley, Raymond S. Camilleri, Amanda Clark, Desmond Creagh, Rachel Rayment, Vickie

Mcdonald, Ashok Roy, Gillian Evans, Siobhan McGuckin, Fionnuala Ni Ainle, Rhona Maclean, William Lester, Michael Nash, Rosemary Scott, Patrick O Brien, and

BloodVolume 124(2):211-219

July 10, 2014

©2014 by American Society of Hematology

Summary of the management of a patient presenting with acute TTP. All women require specialist obstetric review, regular fetal growth scan, and uterine artery Doppler monitoring.

Marie Scully et al. Blood 2014;124:211-219

©2014 by American Society of Hematology

Symptoms documented in women presenting with pregnancy-associated TTP. Acute collapse, requiring intubation and ventilation; cardiac, chest pain and increased troponin T; PE, pulmonary

emboli; TIA, transient ischemic attack.

Marie Scully et al. Blood 2014;124:211-219

©2014 by American Society of Hematology

Placental histology in women with pregnancy-associated TTP and following treatment.

Marie Scully et al. Blood 2014;124:211-219

©2014 by American Society of Hematology

Summary of patients presenting with TTP in pregnancy.

Marie Scully et al. Blood 2014;124:211-219

©2014 by American Society of Hematology