Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated...

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Synthesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, substituted with various saturated and unsaturated side chains via palladium catalyzed cross-coupling reactions el` ene Henon, Fabrice Anizon, Roy Golsteyn, St´ ephane Leonce, Robert Hofmann, Bruno Pfeiffer, Michelle Prudhomme To cite this version: el` ene Henon, Fabrice Anizon, Roy Golsteyn, St´ ephane Leonce, Robert Hofmann, et al.. Syn- thesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, sub- stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic and Medicinal Chemistry, Elsevier, 2006, 14, pp.3825-3834. <10.1016/j.bmc.2006.01.030>. <hal-00023499> HAL Id: hal-00023499 https://hal.archives-ouvertes.fr/hal-00023499 Submitted on 27 Feb 2007 HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destin´ ee au d´ epˆ ot et ` a la diffusion de documents scientifiques de niveau recherche, publi´ es ou non, ´ emanant des ´ etablissements d’enseignement et de recherche fran¸cais ou ´ etrangers, des laboratoires publics ou priv´ es.

Transcript of Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated...

Page 1: Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic

Synthesis and biological evaluation of new

dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones,

substituted with various saturated and unsaturated side

chains via palladium catalyzed cross-coupling reactions

Helene Henon, Fabrice Anizon, Roy Golsteyn, Stephane Leonce, Robert

Hofmann, Bruno Pfeiffer, Michelle Prudhomme

To cite this version:

Helene Henon, Fabrice Anizon, Roy Golsteyn, Stephane Leonce, Robert Hofmann, et al.. Syn-thesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, sub-stituted with various saturated and unsaturated side chains via palladium catalyzed cross-coupling reactions. Bioorganic and Medicinal Chemistry, Elsevier, 2006, 14, pp.3825-3834.<10.1016/j.bmc.2006.01.030>. <hal-00023499>

HAL Id: hal-00023499

https://hal.archives-ouvertes.fr/hal-00023499

Submitted on 27 Feb 2007

HAL is a multi-disciplinary open accessarchive for the deposit and dissemination of sci-entific research documents, whether they are pub-lished or not. The documents may come fromteaching and research institutions in France orabroad, or from public or private research centers.

L’archive ouverte pluridisciplinaire HAL, estdestinee au depot et a la diffusion de documentsscientifiques de niveau recherche, publies ou non,emanant des etablissements d’enseignement et derecherche francais ou etrangers, des laboratoirespublics ou prives.

Page 2: Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic
Page 3: Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic
Page 4: Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic
Page 5: Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic
Page 6: Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic
Page 7: Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic
Page 8: Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic
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Page 12: Synthesis and biological evaluation of new dipyrrolo[3,4-a ... · stituted with various saturated and unsaturated side chains via palladium catalyzed cross- coupling reactions. Bioorganic