www.sciencemag.org/cgi/content/full/340/6129/157/DC1

Supplementary Materials for

Deep Homology of Arthropod Central Complex and Vertebrate Basal Ganglia

Nicholas J. Strausfeld* and Frank Hirth*

*Corresponding author. E-mail: flybrain@neurobio.arizona.edu (N.J.S.); frank.hirth@kcl.ac.uk (F.H.)

Published 12 April 2013, Science 340, 157 (2013)

DOI: 10.1126/science.1231828

This PDF file includes:

Table S1

Fig. S1

References

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Table S1. Behaviors regulated by neuronal activity of vertebrate basal ganglia and insect central complex. Vertebrate Basal Ganglia Insect Central Complex Striatum, Globus Pallidus Protocerebral Bridge, Subthalamic nucleus, Fan-Shaped Body, Ellipsoid Body, Substantia nigra Lateral Accessory Lobe ___________________________________________________________________________________ Postural muscle tone (78) Coordinated locomotion (78) Coordinated locomotion (47) Goal-directed movement (79) Goal-directed movement (47) Saccadic eye movement (78)

Visual orientation and Visual orientation and space integration (80) space integration (25) Sleep (78) Sleep (39, 41, 82) Arousal (78) Arousal (39, 83) Attention (78) Attention (84) Courtship/sexual behavior (85) Sensorimotor learning (81) Place memory (86, 87) Habit learning (4, 81) Reward-seeking behavior (4, 80) Reward-seeking behavior (40, 43, 88) Emotional expression (78) ___________________________________________________________________________________

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Fig. S1. Frontal autofluorescent section of the brain of the fruit fly, Drosophila melanogaster showing the mid-line position (box) of the central complex’s fan-shaped body. The 3-dimensional reconstruction (modified from ref. 47) illustrates the sequence of central complex synaptic neuropils and their spatial arrangements. Rostro-caudally these are: the protocerebral bridge (PB), the fan-shaped body (FB), the noduli (NO), the ellipsoid body (EB), and the lateral accessory complex (LX) comprising the lateral accessory lobe (LAL) and bulb (BU). In Drosophila, but not in other arthropods, the lateral margins of ellipsoid body meet at the midline to form an almost perfect torus.

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