SIBUR-NEFTEKHIM JSC SAFETY DATA SHEET METHYL …Keep people away. Isolate fire and deny unnecessary...
Transcript of SIBUR-NEFTEKHIM JSC SAFETY DATA SHEET METHYL …Keep people away. Isolate fire and deny unnecessary...
VERSION: 1.2
DATE CREATED: 16/11/2018
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SIBUR-NEFTEKHIM JSC
SAFETY DATA SHEET According to Regulations (EC) 1907/2006 (REACH), (EC) 1272/2008 (CLP) & (EU) 2015/830
METHYL ACRYLATE
VERSION: 1.2
DATE CREATED: 16/11/2018
SECTION 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND
COMPANY/UNDERTAKING
1.1 Product identifier
NAME OF SUBSTANCE: Methyl acrylate
SYNONYMS: methyl propenoate; methyl prop-2-enoate; 2-propenoic acid, methyl
ester; acrylic acid methyl ester
TRADE NAMES: Methyl acrylate; acrylic acid methyl ester
CAS #: 96-33-3
EC #: 202-500-6
Index No (CLP): 607-034-00-0
REGISTRATION #: 01-2119459302-44-0011
1.2 Relevant identified uses of the substance Most common technical function of substance:
- Intermediates
- Laboratory chemicals
For the detailed identified uses of the product see Annex 1.
The use of the substance should be limited to those specified in Annex 1.
1.3 Details of the safety data sheet supplier
SUPPLIER:
Company name: SIBUR-NEFTEKHIM JSC
Address: Building 390, Eastern Industrial Zone, Dzerzhinsk,
Nizhniy Novgorod region, 606000, Russian Federation
Contact phone: +7 8313 27-59-09
Fax: +7 8313 27-59-99
Email Address: [email protected]
Emergency Telephone: +7 8313 27-52-98 (office hours only, GMT+3)
Emergency phone in
the country of delivery:
112 (Please note that emergency numbers may vary depending upon the
country of delivery though 112 remains valid as universal number)
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ONLY REPRESENTATIVE:
Company name: Gazprom Marketing and Trading France
Address: 68 avenue des Champs-Elysées, Paris, 75008, France
Contact phone: +33 1 42 99 73 50
Fax: +33 1 42 99 73 99
Email address: [email protected]
SECTION 2. HAZARDS IDENTIFICATION
2.1 Classification and labelling according to EC/1272/2008 Annex VI (CLP (GHS)):
Physical/Chemical Hazards:
Flam. Liquid 2 (Hazard statement: H225: Highly flammable liquid and vapour.)
Health Hazards:
Acute Tox. 4 (Hazard statement: H302: Harmful if swallowed)
Acute Tox. 4 (Hazard statement: H312: Harmful in contact with skin)
Acute Tox. 3 (Hazard statement: H331: Toxic if inhaled)
Skin Irrit. 2 (Hazard statement: H315: Causes skin irritation)
Eye Irrit. 2 (Hazard statement: H319: Causes serious eye irritation)
Skin Sens. 1 (Hazard statement: H317: May cause an allergic skin reaction)
Specific target organ toxicity - single: STOT Single Exp. 3 (Hazard statement: H335: May cause
respiratory irritation). Route of exposure: Inhalation.
Environmental hazards:
Aquatic Chronic 3. (H412: Harmful to aquatic life with long lasting effects.)
2.1.1 CLP LABELLING:
Signal word: Danger
Hazard pictogram:
GHS02: flame GHS06: skull and crossbones
2.1.2 Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. – No smoking.
P271 Use only outdoors or in a well-ventilated area.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash hands thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P241 Use explosion-proof electrical/ventilating/lighting/equipment.
P233 Keep container tightly closed.
P273 Avoid release to the environment.
Precautionary Statements (Response):
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER
P302+P352 IF ON SKIN: Wash with plenty of soap and water
P332+ P313 If skin irritation occurs: Get medical advice/ attention.
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P303 + P361 + P353 If on skin (or hair): Remove/Take off immediately all contaminated clothing.
Rinse skin with water/shower.
P304+P340 IF INHALED: Remove to fresh air and keep at rest in a position comfortable for
breathing.
P337 + P313 If eye irritation persists: Get medical advice/attention.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P370 + P378 In case of fire: Use water spray, dry powder, foam or carbon dioxide for extinction.
Precautionary Statements (Disposal):
P501 Dispose of contents/container to hazardous or special waste collection point.
Precautionary Statements (Storage):
P405 Store locked up.
P410+P403: Protect from sunlight. Store in a well-ventilated place.
P235 +P410 Keep cool. Protect from sunlight.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
2.2 Other hazards:
Assessment PBT / vPvB:
According to Annex XIII of Regulation (EC) No.1907/2006 concerning the Registration,
Evaluation, Authorisation and Restriction of Chemicals (REACH):
- not fulfilling PBT (persistent/bioaccumulative/toxic) criteria;
- not fulfilling vPvB (very persistent/very bioaccummulative) criteria.
SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS
Name/EC No EC No CAS No Content
(w/w) %
Classification Regulation (EC) No
1272/2008 (CLP)
Methyl acrylate
Index No(CLP):
607-034-00-0
202-500-6 96-33-3 99.7 – 99.95
H225; H302; H312; H315; H317;
H319; H331; H335
The product does not contain impurities or additives that could affect product labelling and
classification according to Regulation (EC) No 67/548/ЕЕС and Regulation (EC) No
1272/2008 (CLP) in the concentration ranges specified (none classification):
Impurities
acrylic acid
Index No(CLP):
607-061-00-8
201-177-9 79-10-7 ≤0.005 none
methyl
propionate
Index No(CLP):
607-027-00-2
209-060-4 554-12-1 ≤0.05 none
Methanol
Index No(CLP):
603-001-00-X
200-659-6 67-56-1 ≤0.05 none
methyl acetate
Index No(CLP):
607-021-00-X
201-185-2 79-20-9 ≤0.04 none
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Name/EC No EC No CAS No Content
(w/w) %
Classification Regulation (EC) No
1272/2008 (CLP)
ethyl acrylate
Index No(CLP):
607-032-00-X
205-438-8 140-88-5 ≤0.03 none
n-butyl acetate
Index No(CLP):
607-025-00-1
204-658-1 123-86-4 ≤0.01 none
isobutyl acrylate
Index No(CLP):
607-115-00-0
203-417-8 106-63-8 ≤0.005 none
butan-2-ol
Index No(CLP):
603-127-00-5
201-158-5 78-92-2 ≤0.005 none
butan-1-ol
Index No(CLP):
603-004-00-6
200-751-6 71-36-3 ≤0.001 none
Additives (this stabilizer inhibit the polymerization of butyl acrylate)
Mequinol
Index No(CLP):
604-044-00-7)
205-769-8 150-76-5 10-20 ppm none
Specific Conc. Limits (СLP): none.
M-factor: none.
SECTION 4. FIRST-AID MEASURES
4.1 Description of first aid measures
If inhaled:
Take the victim outside. If he/she is not breathing, give artificial respiration; if mouth to mouth use
rescuer protection (pocket mask, etc). If breathing is difficult, oxygen should be administered by
qualified personnel. Call a physician or transport to a medical facility.
Skin contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated
clothing. Seek medical attention if symptoms occur or irritation persists. Wash clothing before
reuse. Discard items which cannot be decontaminated, including leather articles such as shoes, belts
and watchbands. Safety shower should be located in immediate work area.
Contact with eyes:
Immediately flush eyes with water; remove contact lenses, if symptoms are present after the first 5
minutes, then continue flushing eyes for at least 15 minutes. Obtain medical attention without delay,
preferably from an ophthalmologist. Eye wash fountain should be located at immediate work area.
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Ingestion:
Immediately rinse mouth and then drink plenty of water, do not induce vomiting, seek medical
attention. Give one cup (8 ounces or 240 ml) of water or milk if available and transport to a medical
facility.
4.2 Note to physician:
Maintain adequate ventilation and oxygenation of the patient. If burn is present, treat as any thermal
burn, after decontamination. Due to irritant properties, swallowing may result in burns/ulceration of
mouth, stomach and lower gastrointestinal tract with subsequent stricture. Aspiration of vomitus
may cause lung injury. Suggest endotracheal/esophageal control if lavage is done. No specific
antidote. Treatment of exposure should be directed at the control of symptoms and the clinical
condition of the patient.
4.3 Emergency Personnel Protection: First Aid responders should pay attention to self-protection and use the recommended protective
clothing (chemical resistant gloves, splash protection).
SECTION 5. FIRE-FIGHTING MEASURES
5.1 Extinguishing Media: Water fog or fine spray. Dry chemical fire extinguishers. Carbon dioxide fire extinguishers. Foam.
Do not use direct water stream. Straight or direct water streams may not be effective to extinguish
fire. Alcohol resistant foams (ATC type) are preferred.
General purpose synthetic foams (including AFFF) or protein foams may function, but will be less
effective.
5.2 Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. Stay upwind. Keep out of low areas
where gases (fumes) can accumulate. Water may not be effective in extinguishing fire. Use water
spray to cool fire exposed containers and fire affected zone until fire is out and danger of reignition
has passed. Fight fire from protected location or safe distance. Consider the use of unmanned hose
holders or monitor nozzles. Do not use direct water stream. This may cause spreading fire.
Eliminate ignition sources. Move container from fire area if this is possible without hazard.
Burning liquids may be moved by flushing with water to protect personnel and minimize property
damage.
5.3 Special Protective Equipment for Firefighters:
Wear positive-pressure self-contained breathing apparatus (SCBA) and protective fire fighting
clothing (includes fire fighting helmet, coat, trousers, boots, and gloves). Avoid contact with this
material during fire fighting operations. If contact is likely, change to full chemical resistant fire
fighting clothing with self-contained breathing apparatus. If this is not available, wear full chemical
resistant clothing with self-contained breathing apparatus and fight fire from a remote location.
5.4 Unusual Fire and Explosion Hazards: Container may vent and/or rupture due to fire. Electrically ground and bond all equipment.
Flammable mixtures of this product are readily ignited even by static discharge. Vapors are heavier
than air and may travel a long distance and accumulate in low lying areas. Ignition and/or flash back
may occur. Flammable mixtures may exist within the vapor space of containers at room
temperature.
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5.5 Special hazards:
Risk of spontaneous and violent self-polymerization if inhibitor is lost or product is exposed to
excessive heat. Polymerization is accompanied with heat emissions, during which the temperature
and gas pressure grow rapidly. In case of uncontrolled polymerization there might occur rapid
release of energy with risk of explosion in closed, non ventilated containers.
Methylacrylate vapors and air produce explosive mixture. Open fire, smoking, local overheating
may cause fire or explosion.
5.6 Hazardous Combustion Products: During a fire, smoke may contain the original material in addition to combustion products of
varying composition which may be toxic and /or irritating. Combustion products may include and
are not limited to: сarbon monoxide, carbon dioxide.
5.7 Further information: In case of a fire in the vicinity a restabilization system should be used if the temperature in the
storage container reaches 45°C. Evacuate area of all unnecessary personnel. In case of a fire in the
vicinity evacuate all personnel in a greater area if the temperature in the storage container reaches
60°C.
5.8 Fire safety measures: Provide possibility to quickly pump out the product in case of emergency from vessels used for storage and processing. Inspect work areas regularly, especially storage vessels, loading and discharge lines checking for combustion gas. Immediately clean product spillages. Provide efficient means of fire fighting for cleaning the accidental spillages. Do not use tools which are not intrinsikally safe for maintenance and repairing at areas, where combastible gases accumulation is possbile. Do not add dry inhibitor to the product by loading it via steam discharge pipes due to the risk of static ignition.
SECTION 6. ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions: Evacuate personnel in the area. Keep unnecessary and unprotected personnel from entering the area.
Keep personnel out of low areas. Keep upwind of spill. Ventilate area of leak or spill. Eliminate all
sources of ignition in vicinity of spill or released vapor to avoid fire or explosion. Vapor explosion
hazard. Keep out of sewers. For large spills, warn public of downwind explosion hazard. Check
area with combustible gas detector before reentering area. Ground and bond all containers and
handling equipment. Use appropriate safety equipment.
6.2 Methods and material for containment and cleaning up:
Small spills: Absorb with materials such as: sand, sawdust.
Large spills: Dike area to contain spill. Contain spilled material if possible. Pump with explosion-
proof equipment.
If available, use foam to smother or suppress. Collect in suitable and properly labeled containers.
6.3 Environmental precautions:
Prevent from entering into soil, ditches, sewers, waterways and/or groundwater.
6.4 Reference to other sections:
Information regarding exposure controls/personal protection and disposal considerations can be
found in section 8 and 13.
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SECTION 7. HANDLING AND STORAGE
7.1 General Handling: Handle in accordance with good industrial hygiene and safety practice. The product may be handled
only by appropriately trained personnel. Facility parts must be checked for polymer residues and
cleaned on regular basis in order to avoid hazardous reactions.
Keep away from heat, sparks and flame. Protect from direct sunlight.
Do not get on skin or clothing. Do not swallow. Avoid contact with eyes. Avoid prolonged or
repeated contact with skin. Avoid breathing vapor.
Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling.
Never use air pressure for transferring product.
Protection against fire and explosion:
No smoking, open flames or sources of ignition in handling and storage area.
Vapors are heavier than air and may travel a long distance and accumulate in low lying areas.
Ignition and/or flash back may occur. Electrically bond and ground all containers and equipment
before transfer or use of material. Containers, even those that have been emptied, can contain
vapors. Do not cut, drill, grind, weld, or perform similar operations on or near empty containers.
Use of non-sparking or explosion-proof equipment may be necessary, depending upon the type of
operation.
Heated containers should be cooled to prevent polymerization. If exposed to fire, keep containers
cool by spraying with water. Emergency cooling must be provided for the eventuality of a fire in the
vicinity.
Sealed containers should be protected against heat as these results in pressure build-up. Avoid
influence of heat.
7.2 Storage:
Minimize sources of ignition, such as static build-up, heat, spark or flame.
Containers should be properly sealed. Store in a dry place. Avoid moisture.
Do not store with less than 10 % headspace above liquid.
Do not store or transfer the product by pressure under inert gases.
The product should be stored with gas containing 6-7% of oxygen (vol.).
This product contains an inhibitor for stabilization during transportation and storage.
Ensure adequate inhibitor and dissolved oxygen level.
Recommended inhibitor level is: 10 to 20 ppm. If storage is prolonged, the inhibitor concentration
should be tested at least every 60 days.
Flammable mixtures may exist within the vapor space of containers at room temperature.
Uninhibited monomer vapors can polymerize and plug relief devices.
Store away from incompatible materials (see STABILITY AND REACTIVITY section).
Storage temperature: <30°C.
Shelf life: use within 12 Months. Avoid prolonged storage
7.3 Storage stability: Storage stability is based upon ambient temperatures and conditions described.
Storage temperature: 45 °C:
A restabilization system should be used if the temperature in the storage container reaches the
indicated value.
All personnel should be evacuated if the temperature in the storage container reaches 60 °C.
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Avoiding polymerization: see STABILITY AND REACTIVITY section
7.4 Suitable materials for containers:
Opaque HDPE plastic container, stainless steel, aluminium, carbon steel, glass-lined container Do
not store in: translucent container aluminum.
Further information on storage conditions:
Vessels should be well protected from penetration of other materials/substances. Provide
designated lines for product loading and discharge.
Pipelines desing should avoid product stagation. Regularly control the combustible gas concentration in work areas.
SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
8.1 Control parameters 8.1.1 Occupational Exposure Limits
International Limit values1)
SUBSTANCE
Methyl acrylate
CAS #96-33-3
LTEL
8 hr
TWA ppm
LTEL
8 hr
TWA mg/m3
STEL
ppm
STEL
mg/m3
Note
Austria 5 18 10 26
Belgium 2 7.2
Denmark 2 7 4 14
European Union 5 18 10 (1) 36 (1) Occupational Exposure Limit
Values
(1) 15 minutes average value
France 5 18 10 36
Germany (AGS) 5 18 5 (1) 18 (1) (1) 15 minutes average value
Germany (DFG) 5 18 5 18 STV 15 minutes average
value
Hungary 18 18
Italy 2 7 10 35
Latvia 20 35(1) (1) 15 minutes average value
Poland 14 28
Spain 2 7.2 skin, sen.
Sweden 10 35 15(1) 50(1) (1) 15 minutes average value
Switzerland 5 18 5 18
The Netherlands - 18 - 36
USA - NIOSH 10 35
USA - OSHA 10 35
1) GESTIS International Limit values:
http://limitvalue.ifa.dguv.de/WebForm_ueliste.aspx
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8.1.2 DNEL/ PNEC values
DN(M)ELs for workers
Exposure
pattern
Route Descriptor DNEL /DMEL Most sensitive
endpoint
Justification/
Remarks
Acute -systemic
effects
Dermal
Acute - systemic
effects
Inhalation
Acute - local
effects
Dermal DNEL 0.49 mg/cm²
Corrected Dose
descriptor: 4.90 mg/cm² (based
on AF of 10)
sensitisation
(skin)
Acute - local
effects
Inhalation
Long-term -
systemic effects
Dermal
Long-term -
systemic effects
Inhalation
Long-term - local
effects
Dermal
Long-term - local
effects
Inhalation DNEL 18 mg/m³ irritation
(respiratory tract)
DN(M)ELs for the general population
Exposure
pattern
Route Descriptor DNEL / DMEL Most sensitive
endpoint
Justification/
Remarks
Acute - systemic
effects
Dermal
Acute - systemic
effects
Inhalation
Acute - systemic
effects
Oral
Acute - local
effects
Dermal DNEL 0.49 mg/cm²
Corrected Dose
descriptor: 4.90 mg/cm² (based
on AF of 10)
sensitisation
(skin)
Acute - local
effects
Inhalation
Long-term -
systemic effects
Dermal
Long-term -
systemic effects
Inhalation
Long-term -
systemic effects
Oral
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Long-term -
local effects
Dermal
Long-term -
local effects
Inhalation DNEL 2.1 mg/m³ irritation
(respiratory tract)
PNEC water
PNEC Assessment
factor
Remarks/Justification
PNEC aqua
(freshwater):
0.00272 mg/L
50 Extrapolation method: assessment factor
The aquatic toxicity of the six acrylic esters (methyl, 2-ethylhexyl, ethyl,
n-butyl, isobutyl, and tert-butyl acrylate) was evaluated as a category. Due
to the moderate volatility and ready biodegradability of most of the
acrylic esters only effect values based on analytically measured
concentrations were used for the derivation of the PNEC. An assessment
factor of 50 was applied to the lowest NOEC value available (0.136
mg/L).
PNEC aqua
(marine water):
0.00027 mg/L
500 Extrapolation method: assessment factor
The aquatic toxicity of the six acrylic esters (methyl, 2-ethylhexyl, ethyl,
n-butyl, isobutyl, and tert-butyl acrylate) was evaluated as a category. Due
to the moderate volatility and ready biodegradability of most of the
acrylic esters only effect values based on analytically measured
concentrations were used for the derivation of the PNEC. Such data are
available from a robust data set of acute studies in three trophic levels
(marine and freshwater species) and long-term results from two trophic
levels (freshwater species) (see PNEC aqua (freshwater) for details). An
assessment factor of 500 was applied to the lowest NOEC value available,
derived from a 21-day chronic life-cycle study with Daphnia magna
(0.136 mg/L).
PNEC aqua
(intermittent
releases): 0.011
mg/L
100 Extrapolation method: assessment factor
The aquatic toxicity of the six acrylic esters (methyl, 2-ethylhexyl, ethyl,
n-butyl, isobutyl, and tert-butyl acrylate) was evaluated as a category. A
robust data set of acute studies in three trophic levels (marine and
freshwater species) is available. Taking all available short-term tests with
freshwater and saltwater species into consideration, the most sensitive
species is Cyprinodon variegatus with an LC50 of 1.1 mg/L. The
recommended assessment factor for the derivation of a PNEC aqua
(intermittent releases) is 100 (ECHA, May 2008).
PNEC sediment
PNEC Assessment
factor
Remarks/Justification
PNEC sediment
(freshwater):
0.0115 mg/kg
sediment dw
Extrapolation method: partition coefficient
Since no experimental data were available for sediment dwelling
organisms, the PNEC sed was estimated using the equilibrium
partitioning method as recommended by the Technical Guidance
Document for Risk Assessment (ECB, 2003) and Guidance on
information requirements and chemical safety assessment, Chapter R.10
(ECHA, May 2008). PNEC sediment in mg/kg sediment ww = 0.00251
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PNEC soil
PNEC Assessment
factor
Remarks/Justification
PNEC soil:
1 mg/kg soil dw
1000 Extrapolation method: assessment factor
For the derivation of the PNEC soil an OECD TG 217 study with an EC50
greater than 1000 mg/kg soil dw based on soil micro-flora (carbon-cycle)
is available. An assessment factor of 1000 is proposed by the Guidance on
information requirements and chemical safety assessment, Chapter R.10
(ECHA, May 2008) for such data. The resulting PNEC soil is 1 mg/kg soil
dw.
This assessment is supported by data from the structural analogue acrylic
acid for which a PNEC soil of 1 mg/kg soil dw was derived based on a
short-term test in Eisenia fetida with an LC50 > 1000 mg/kg dw and a
long-term toxicity test with a NOEC of 100 mg/kg soil dw based on soil
micro-flora (carbon-cycle).
PNEC sewage treatment plant
Value Assessment
factor
Remarks/Justification
PNEC STP: 10
mg/L
10 Extrapolation method: assessment factor
For the derivation of the PNEC STP an activated sludge inhibition test
(BODm test) has to be taken into account. The 72-h NOEC for domestic
activated sludge was 100 mg/L. An assessment factor of 10 was applied to
this value leading to a PNEC STP of 10 mg/L. This value is supported by
the assumption that the test substance was not inhibitory to
microorganisms in a positive ready biodegradability test.
PNEC oral (secondary poisoning)
PNEC Assessment
factor
Remarks/Justification
PNEC oral:
0.0011 g/kg food
90 Based on a log Kow value of 0.74, no bioaccumulation of Methyl acrylate
in organisms is expected. Hence, secondary poisoning will not be an
important factor in the hazard assessment. Nevertheless, a PNEC oral was
determined. Since no data on acute or chronic toxicity towards birds are
available, the PNEC oral for secondary poisoning was derived from a
subchronic drinking water study with rats (Dow 1981). The NOAEL
(systemic) was 5 mg/kg bw corresponding to a NOEC (food) = 0.1E-03
kg/kgfood. The assessment factor for a 90-day study in mammals is 90
resulting in a PNEC oral (mammal) = 1.1E-06 kg/kg food.
8.2 Exposure Controls
Personal protective equipment
Eye protection/Face Protection:
Use chemical goggles. Chemical goggles should be consistent with EN 166 or equivalent. Eye wash
fountain should be located in immediate work area. If exposure causes eye discomfort, use a full-
face respirator.
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Skin Protection:
Use protective clothing chemically resistant to this material. Selection of specific items such as face
shield, boots, apron, or full body suit will depend on the task. Safety shower should be located in
immediate work area. Remove contaminated clothing immediately, wash skin area with soap and
water, and launder clothing before reuse or dispose of properly. Items which cannot be
decontaminated, such as shoes, belts and watchbands, should be removed and disposed of properly.
Respiratory protection:
Respiratory protection should be worn when there is a potential to exceed the exposure limit
requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, use
an approved respirator. When respiratory protection is required, use an approved positive-pressure
self-contained breathing apparatus or positive-pressure airline with auxiliary self-contained air
supply. For emergency conditions, use an approved positive-pressure self-contained breathing
apparatus. In confined or poorly ventilated areas, use an approved self-contained breathing
apparatus or positive pressure air line with auxiliary self-contained air supply.
Hand protection:
Use chemical resistant gloves classified under Standard EN374: Protective gloves against chemicals
and micro-organisms.
Examples of preferred glove barrier materials include: Polyethylene, Chlorinated polyethylene,
Styrene/butadiene rubber, Polyvinyl alcohol ("PVA"), Ethyl vinyl alcohol laminate ("EVAL").
Examples of acceptable glove barrier materials include: Viton, Butyl rubber, Natural rubber
("latex"), Polyvinyl chloride ("PVC" or "vinyl"), Nitrile/butadiene rubber ("nitrile" or "NBR").
When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or
higher (breakthrough time greater than 240 minutes according to EN 374) is recommended.
When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough
time greater than 60 minutes according to EN 374) is recommended.
NOTICE: The selection of a specific glove for a particular application and duration of use in a
workplace should also take into account all relevant workplace factors such as, but not limited to:
Other chemicals which may be handled, physical requirements (cut/puncture protection, dexterity,
thermal protection), potential body reactions to glove materials, as well as the
instructions/specifications provided by the glove supplier.
Ingestion:
Avoid ingestion of even very small amounts; do not consume or store food or tobacco in the work
area; wash hands and face before smoking or eating.
Engineering controls: Ventilation: Use engineering controls to maintain airborne level below exposure limit requirements
or guidelines. If there are no applicable exposure limit requirements or guidelines, use only in
enclosed systems or with local exhaust ventilation. Exhaust systems should be designed to move
the air away from the source of vapor/aerosol generation and people working at this point. Lethal
concentrations may exist in areas with poor ventilation.
For more information please see the relevant exposure scenario in Appendix II of this SDS.
SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
Property Value Remarks
Physical state at 20°C liquid
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Property Value Remarks
and 1013 hPa
Colour
Odour
Form: volatile
Colourless
Pungent, acrid odor
Melting / freezing point -76.5 °C at 1013.25 hP
Measured
(The Merck Index - An Encyclopedia
of Chemicals, Drugs, and
Biologicals.)
Boiling point 80.1 °C at 1013.25 hPa Measured
(BASF AG Dampfdruck von
Methylacrylat, Ethylacrylat und
Butylacrylat, 1983)
Relative density 0.95 g/cm3 at 20 °C Measured
(CRC Handbook of Chemistry and
Physics. 76th ed./ Lide, D.R. (ed.))
Vapour pressure 90 hPa at 20°C Measured
(BASF AG Dampfdruck von
Methylacrylat, 1983)
Water solubility 60 g/l at 20°C
(60000 mg/L at 20°C)
Measured
The Merck Index, 14th Edition ver.
14.4. /Smyth, Carpenter, 2006;
Documentation of the Threshold
Limit Values and Biological
Exposure Indices, 6th ed, 1992
Partition coefficient
n-octanol/water
(log value)
0.739 at 25 °C OECD Guideline 107 (Partition
Coefficient (n-octanol / water), Shake
Flask Method), BASF AG
Viscosity 0.472 mPas at 25 °C Measured
(Design Institute for Physical
Properties, Sponsored by AIChE,
2005)
Flash point closed cup
-2.8 °C
(270.4 K at 1013 hPa)
Measured
American Conference of
Governmental Industrial Hygienists,
Inc. (1991)
Flammability
Highly flammable.
The substance has no pyrophoric
properties and does not liberate
flammable gases on contact with
water.
Flammability derived from flash
point and boiling point.
Based on chemical structure
pyrophoric properties and
flammability in contact with water
are not predicted.
Lower explosion limit:
Upper explosion limit:
2.4(%)
18.6 (%)
Literature data.
GESTIS Substance database (2008)
Explosive properties non explosive There are no chemical groups
associated with explosive properties
present in the molecule.
In accordance with column 2 of
REACH Annex VII, the
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Property Value Remarks
explosiveness of the substance does
not need to be tested, because there
are no chemical groups associated
with explosive properties in the
molecule
Self-ignition temperature 468 °C
Oxidising properties no oxidising properties The Substance is incapable of
reacting exothermically with
combustible materials.
In accordance with column 2 of
REACH Annex VII, the oxidising
properties do not need to be tested,
because the substance is incapable of
reacting exothermically with
combustible materials on the basis of
the chemical structure.
Granulometry not applicable Substance is marketed or used in a
non solid or granular form. In
accordance with column 2 of
REACH Annex VII, the particle size
distribution (Granulometrie) study
does not need to be performed as the
substance is marketed or used in a
non solid or granular form
Stability in organic
solvents and identity of
relevant degradation
products
The stability of the substance is not
considered as critical.
In accordance with column 1 of
REACH Annex IX, the test does not
need to be conducted because the
stability of the substance is not
considered as critical
Dissociation constant not applicable The substance does not contain any
ionic structure.
In accordance with section 1 of
REACH Annex XI, the dissociation
constant study does not need to be
performed because the substance
does not contain any ionic structure.
Surface tension not surface active In accordance with column 2 of
REACH Annex VII, the surface
tension of the substance does not
need to be tested because due to its
chemical structure, no surface
activity is predicted.
9.2 Other information
Self-accelerating
polymerisation
temperature (SAPT)
> 50 °C at the inhibitor level not less than 15 ppm
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SECTION 10. STABILITY AND REACTIVITY
10.1 Chemical stability:
Stable under recommended storage conditions. Unstable at elevated temperatures. Hygroscopic.
10.2 Reactivity:
The product undergoes the following reactions: polymerization, hydrolyzation, oxidation,
hydration, interesterification, halogenation.
10.3 Possibility of hazardous reactions:
Risk of spontaneous and violent self-polymerization if inhibitor is lost or product is exposed to
excessive heat.
Polymerization can be catalyzed by: аbsence of air, free radical initiators, oxidizing agents, high
temperature, peroxides. Presence of water can accelerate rate of polymerization. Uninhibited
monomer vapors can polymerize and plug relief devices.
Under uncontrolled polymerization there might occur rapid release of energy with risk of explosion
in closed, non ventilated containers.
10.4 Conditions to avoid:
Avoid temperatures above 30°C. Avoid direct sunlight. Avoid prolonged storage. Avoid inhibitor
loss. Exposure to elevated temperatures can cause product to decompose. Avoid static discharge.
Avoid moisture. Do not blanket or purge with an inert gas to avoid depleting the oxygen
concentration.
10.5 Incompatible materials:
Avoid contact with oxidizing materials.
Avoid contact with: alcohols, аldehydes, amines, free radical initiators, halides, mineral acids,
peroxides, strong inorganic bases.
Avoid contact with metals such as: brass, copper.
Avoid unintended contact with: activated carbon, aluminum oxide, silica gel.
Avoid contact with absorbent materials such as: cellulose-based absorbents, clay-based absorbents.
Avoid unintended contact with peroxides.
10.6 Hazardous decomposition products:
Thermal Decomposition. Decomposition products depend upon temperature, air supply and the
presence of other materials.
SECTION 11. TOXICOLOGICAL INFORMATION
Property Results Remarks
Acute toxicity
Oral LD50: ca. 768 mg/kg bw (rat, male) key study, experimental result
OECD TG 401 (Acute Oral Toxicity),
BASF AG (1958)
Inhalation LC50 (4 h): 10.382 mg/L air (rat,
male/female)
key study, experimental result
OECD Guideline 403 (Acute
Inhalation Toxicity), BASF SE (2012)
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Dermal LD50 (dermal): ca. 1250 mg/kg bw
(rabbit, occlusive)
key study, experimental result
Acute dermal toxicity study in rabbits
conducted according to the method
described by Draize et al. (1944).
Smyth HF and Carpenter CP (1948)
Irritation/Corrosivity:
Skin contact with methyl acrylate causes irritation. Methyl acrylate may be irritating to the
respiratory system, and may cause severe damage to the eyes.
EU classification according to Annex I of Directive 67/548/EEC: Xi, R36/37/38
GHS classification (GHS UN rev.3, 2009):
- Skin corrosion/irritation: Category 2
- Serious eye damage/eye irritation: Category 2
- Specific target organ toxicity, Single exposure: Category 3 (May cause respiratory irritation)
Eye irritant/ corrosive rabbit: irritating
rabbit: corrosive
key study, experimental result
BASF test (BASF AG 1958);
Draize Test /TNO (1978)
Skin irritant rabbit: irritating key study, experimental result
OECD TG 404 (Acute Dermal
Irritation / Corrosion)
BASF AG test (1982)
Respiratory tract
rats and mice, inhalation, vapour:
irritating effects on the respiratory
system
key study, experimental result
BASF test (BASF AG 1979)
Sensitisation: After repeated skin contact with Methyl acrylate sensitization is possible
EU classification according to Annex I of Directive 67/548/EEC: Xi, R43
GHS classification (GHS UN rev.3, 2009):
- Skin Sensitization Category 1 B
Skin sensitization
Mouse: sensitizing
Stimulation index: 3.8
key study, experimental result
OECD Guideline 429 (Skin
Sensitisation: Local Lymph Node
Assay)
Syngenta CTL (2006)
Respiratory system There is no information available on
the potential for MA to produce
respiratory sensitisation in animals.
Repeated dose toxicity
EU classification according to Annex VI of Directive 67/548/EEC: no
classification required
GHS classification (GHS UN rev.3, 2009): Specific Target Organ
Toxicity: Repeated Exposure: no classification required
Oral
NOAEL = 5 mg/kg bw/d
rat, male/female
LOAEL: 20 mg/kg
rat, male/female;
Effects on kidney weight
key study, experimental result
OECD TG 408 (Repeated Dose 90-Day
Oral Toxicity in Rodents)
Dow Chemical Co. (1981)
Inhalation
NOAEC: 0.082 mg/L air
Rat, male/female
key study, experimental result
OECD TG 413 (Subchronic Inhalation
Toxicity: 90-Day)
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LOAEC: 0.44 mg/L air
rat, male/female
(body weight change and organ
weight changes (lung and liver))
LOAEC: 58 mg/m3
Rat: nasal and ocular local effects
NOAEC >= 519 mg/m3.
BASF AG (1978)
BASF AG (1980)
Dermal
Not applicable No subacute or subchronic repeated
dose studies with dermal application are
available for Methyl acrylate.
Mutagenicity Genetic toxicity: negative
EU classification according to Annex VI of Directive 67/548/EEC: no
classification required
GHS classification (GHS UN rev.3, 2009): no classification required
Methyl acrylate was negative in bacterial mutation tests. In gene mutation
assays in mammalian cells, i. e. HGPRT and XPRT assays, MA was clearly
negative. MA seems to have some potential for genotoxicity in mammalian
cells, presumably by a clastogenic mechanism. Since this effect is limited to
doses with moderate to strong cytotoxicity, it is highly unlikely that this
potential will be expressed in vivo. Methyl acrylate was negative in several in
vivo mouse micronucleus assays. Thus, taking the negative test results in vivo
for MA into consideration, it can be assumed that MA will not cause any DNA
damage, i. e. genotoxicity in vivo.
In vitro data
negative:
bacterial reverse mutation assay e.g.
Ames test, gene mutation
(S. typhimurium TA)
key study, experimental result
The study was conducted according to
the method described by Ames BN et al.
(1975). Mut. Res. 31: 347-364
BASF AG (1977);
HGPRT assay / Moore MM et al. (1989;
1991);
XPRT mutation assay performed
according to the procedure described by
Oberly et al. (1987, 1990) with some
modifications.
Methyl acrylate was tested at two
laboratories: Case Western Reserve
University (CWR) and SRI International
(SRI)/ Zeiger E et al. (1987);
Rannug et al (1976). Chem.-Biol.
Interact. 12: 251-263/ Waegemaekers
THJM and Bensink MPM (1984)
In Vivo Data negative:
micronucleus assay (chromosome
aberration)
mouse, inhalation: vapour
key study, experimental result
Sofuni T, Hayashi M, Matsouka A
(Bull National Institute of Hygiene
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mouse, oral:
Sciences 102: 84-90, 1984 in Japanese)
Hachiya N et al. (1981)
Carcinogenicity No carcinogenic effects
Inhalation Neoplastic effects: no effects
Methyl acrylate showed no evidence
of carcinogenicity in a 2-year
vapour inhalation study in Sprague-
Dawley rats up to the highest tested
dose:
rat (Sprague-Dawley), male/female
inhalation: vapour (whole body)
NOAEC (carcinogenicity):
>=0.519 mg/L air
LOAEC (toxicity): 0.058 mg/L air
(Local effects (nasal and ocular))
key study, experimental result
OECD TG 453 (Combined Chronic
Toxicity / Carcinogenicity Studies)
Inbifo (1985)Reininghaus W, Koestner
A, and Klimisch H-J (1991)
Dermal This information is not available.
Toxicity for
reproduction:
No effect on reproductive organs
EU classification according to Annex VI of Directive 67/548/EEC:
no classification required
GHS classification (GHS UN rev.3, 2009): no classification required
Effects on fertility In a two-generation study in which
groups of rats were whole-body
exposed to methyl acrylate vapours,
no effects on reproductive function
(i. e. fertility) were observed.
NOEC (reproductive toxicity):=
ca. 0.269 mg/L air = 75 ppm
(rat; male/female)
key study, experimental result
OECD TG 416
EPA OPPTS 870.3800 (Reproduction
and Fertility Effects)
JMAFF, Guideline 2-1-17,
Reproduction Study (2000)
The Dow Chemical Company (2009)
Developmental toxicity No indications of a developmental
toxic / teratogenic effect were seen
in animal studies:
Inhalation: vapour (whole body),
Rabbit:
NOAEL (maternal toxicity): 15 ppm
NOAEL (developmental toxicity):
45 ppm
inhalation: vapour (whole body)
rat (Sprague-Dawley):
NOAEC (maternal toxicity): ca.
0.089 mg/L air (nominal) (body
weight)
NOAEC (teratogenicity):
>= 0.357 mg/L air (nominal)
LOAEC (fetotoxicity):
key study, experimental result
OECD TG 414
EPA OPPTS 870.3700 (Prenatal
Developmental Toxicity Study)
BASF SE (2009)
OECD TG 414 (Prenatal Developmental
Toxicity Study)
Saillenfait AM et al. (1999)
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ca. 0.357 mg/L air (nominal) (fetal
body weight)
Toxicokinetics
(absorption,
metabolism,
distribution and
elimination)
Methyl acrylate is readily absorbed by the oral, dermal and inhalation
routes and the major portion is rapidly hydrolyzed by carboxyesterases to
acrylic acid and methanol. Greater than 90 % is excreted within 72 hours,
primarily via the lungs (> 50 %) as CO2, and kidneys (40-50 %) as
products of methyl acrylate-glutathione conjugation. Dermal absorption is
somewhat slower and appears to follow irritation of the skin, possibly
reflecting an initial de-esterification, with subsequent absorption of the
acrylic acid formed.
Other effects None.
SECTION 12. ECOLOGICAL INFORMATION
Property
Value
Remarks
AQUATIC TOXICITY
Fish:
Short-term toxicity
LC50 (96 h): 3.4 mg/L test mat.
Salmo gairdneri (new name:
Oncorhynchus mykiss)/ freshwater
LC50 (96 h, flow through) = 1.1 mg/L
(measured)
Cyprinodon variegates/saltwater
key study, experimental result
OECD Guideline 203 (Fish, Acute
Toxicity Test)
Basic Acrylic Monomer
Manufacturers (1995)
OECD Guideline 203 (Fish, Acute
Toxicity Test)
Wildlife International Ltd. (1995)
Long-term toxicity to fish: Not applicable
In accordance with section 3 of REACH Annex XI, the study does not need to be conducted. The
use of methyl acrylate as a monomer, almost exclusively in closed systems for the production of
polymers, indicates that environmental exposure would be limited. The volatility of methyl acrylate
provides for volatilization of any releases to the air. Methyl acrylate is slowly photodegradable and
readily biodegradable, and accidental releases to the environment would not result in accumulation
or persistence. The relatively high water solubility and corresponding low log Kow indicate that no
bioaccumulation potential exists.
In order to assess long-term toxicity towards aquatic organisms, a 21-day chronic life-cycle study
with Daphnia magna was conducted with the structurally-related ethyl acrylate. The respective
NOEC was 0.19 mg/L.
Aquatic invertebrates
Short-term toxicity
EC50 (48 h) = 2.6 mg/L (measured),
Daphnia magna/ freshwater/flow-
through
LC50 (96 h) = 1.6 mg/L (measured)
Mysidopsis bahia (new name:
Americamysis bahia) /saltwater/
flow-through
key study, experimental result
OECD Guideline 202 (Daphnia
sp. Acute Immobilisation Test)
Basic Acrylic Monomer
Manufacturers Inc. (1995a)
EPA OTS 797.1930 (Mysid Acute
Toxicity Test)
BASF AG (2001)
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Long-term toxicity
(Daphnia Magna)
NOEC (21 d): 0.136 mg/L test mat.
meas. (TWA) based on: reproduction
LOEC (21 d): 0.457 mg/L test mat.
meas. (TWA) based on: reproduction
NOEC (21 d): 0.19 mg/L test mat.
meas. (arithm. mean) based on:
reproduction
LOEC (21 d): 0.45 mg/L test mat.
meas. (arithm. mean)) based on:
reproduction
key study, experimental result
Read-across to n-butyl acrylate
(CAS 141-32-2)
OECD Guideline 211 (Daphnia
magna Reproduction Test)
BASF SE (2009c)
Read-across to Ethyl acrylate
(CAS 140-88-5)
EPA OTS 797.1330 (Daphnid
Chronic Toxicity Test)
ABC Laboratories, Inc. (1997)
Algae and aquatic plants
(Selenastrum
capricornutum, new
name: Pseudokirchnerella
subcapitata) (algae)
EC50 (72 h): 3.55 mg/L test mat.
based on: growth rate/ freshwater/ static
key study, experimental result
OECD Guideline 201 (Alga,
Growth Inhibition Test)
Basic Acrylic Monomer
Manufacturers Inc. (1995b)
Toxicity to aquatic micro-
organisms
EC10 (72 h): > 100 mg/L test mat.
(nominal) based on: respiration rate
key study, experimental result ASTM Microbial Inhibition
Testing Procedure
Basic Acrylic Monomer
Manufacturers Inc. (1996)
Sediment organisms: Not applicable In Annex IX of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity testing shall be
proposed by the registrant if the chemical safety assessment indicates the need to investigate further the
effects on sediment organisms.
According to Annex I of this regulation, the chemical safety assessment triggers further action when the
substance or the preparation meets the criteria for classification as dangerous according to Directive
67/548/EEC or Directive 1999/45/EC or is assessed to be a PBT or vPvB.
The hazard assessment of nBA reveals neither a need to classify the substance as dangerous for the
environment, nor is it a PBT or vPvB substance. Furthermore, due to the physico-chemical properties of the
substance and its ready biodegradability, a considerable exposure of the sediment compartment is unlikely.
Therefore, a long-term toxicity study in sediment organisms is not provided. The PNEC sediment can be
estimated based on the equilibrium partitioning method.
Toxicity to soil macro-organisms: Not applicable In accordance with section 3 of REACH Annex XI, the study does not need to be conducted. Since n-butyl
acrylate is readily biodegradable and no direct releases to soil from point sources are known, no significant
exposure of the terrestrial compartment is expected.
Toxicity to soil micro-
organisms
EC50 (28 d): > 1000 mg/kg soil dw test
mat.
(nominal) based on: respiration rate
key study, experimental result
OECD Guideline 217 (Soil
Microorganisms: Carbon
Transformation Test)
BASF SE (2010)
Toxicity to terrestrial plants: Not applicable In accordance with section 3 of REACH Annex XI, the study does not need to be conducted. Since n-butyl
acrylate is readily biodegradable and no direct releases to soil from point sources are known, no significant
exposure of the terrestrial compartment is expected
Toxicity to birds: Not applicable.
In accordance with section 1 and 3 of REACH Annex XI, the study does not need to be conducted.
Since no exposure of birds is expected, testing of birds is not required.
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DEGRADATION
Abiotic degradation: Methyl acrylate does not absorb UV radiation at wavelengths > 290 nm, i. e.
methyl acrylate does not directly photolyse. However, it is susceptible to photo-oxidation via vapour
phase reaction with photochemically-produced hydroxyl radicals and ozon. The substance will
hydrolyse slowly in contact with water under environmental conditions.
Hydrolysis In contact with water Methyl
acrylate will hydrolyse slowly:
Half-life (DT50):
t1/2 (pH 7): > 28 d at 25 °C
t1/2 (pH 11): 1.8 h at 25 °C
key study, experimental result
EPA OTS 796.3500
(Hydrolysis as a Function of pH at
25°C)
BASF AG (1998)
Phototransformation in air After evaporation or exposure to
the air, Methyl acrylate will be
slowly degraded by
photochemical processes:
Half-life (DT50):
40.9 h (24-h day)
Concentration of OH radicals:
0.5E+06 OH/cm3
Degradation rate constant:
9.423 E-12 cm3/molecule*sec
key study, calculated
(Q)SAR
Computer programme: SRC AOP
v1.92 BASF SE (2008)
Biodegradation: Methyl acrylate is readily biodegradable according to OECD criteria.
Biodegradation in water readily biodegradable:
% Degradation of test substance:
90 — 100 after 28 d
inherently biodegradable:
% Degradation of test substance:
50 — 60 after 28 d
(O2 consumption)
experimental result
OECD OECD TG 310 (Ready
Biodegradability - CO2 in Sealed
Vessels (Headspace Test)
BASF AG (2005)
OECD Guideline 301 D (Ready
Biodegradability: Closed Bottle
Test)
Basic Acrylic Monomer
Manufacturers, Inc. (1996)
Biodegradation in soil study scientifically unjustified In accordance with column 2 of
REACH Annex IX, no simulation
tests in soil are required, since
Methyl acrylate is readily
biodegradable according to OECD
criteria.
ENVIRONMENTAL DISTRIBUTION
Adsorption/desorption Adsorption of Methyl acrylate to
solid soil phase is not expected
Adsorption coefficient:
Koc at 20°C = 6.4
log Koc = 0.81
Study type: adsorption (soil)
Calculated, QSAR
PCKOCWIN v1.66
BASF SE, 2008b
Volatilization From the water surface, Methyl
acrylate will slowly evaporate
into the atmosphere.
Henry's Law constant H:
9.37 Pa m³/mol at 25 °C
key study, estimated by
calculation, (Q)SAR
SRC HENRYWIN v3.10
BASF SE (2008c)
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Environmental distribution
Percent distribution in media:
Air (%): 81.9
Water (%): 18
Soil (%): 0.01
Sediment (%): 0.01
Susp. sediment (%): 0
Biota (%): 0
Aerosol (%): 0
key study, estimated by
calculation
Calculation according to Mackay,
Level I
BASF SE (2008d)
BIOACCUMULATION: Methyl acrylate does not accumulate in organisms
Aquatic bioaccumulation BCF: 3.162 (log Pow)
log BCF: 0.5
The BCF was calculated based on
the log Pow = 0.74
key study, estimated by
calculation
SRC BCFBAF v3.00
BASF SE (2009a)
SECONDARY POISONING PNEC oral = 0.0011 g/kg food
No bioaccumulation of Methyl
acrylate in organisms is expected.
Secondary poisoning will not be an
important factor in the hazard
assessment. Nevertheless, a PNEC
oral was determined.
The PNEC oral for secondary
poisoning was derived from a
subchronic drinking water study
with rats, based on
NOAEL (systemic) =5 mg/kg bw
or NOEC(food) = 0.1E-03 kg/kg
food. PNEC oral (mammal) =
1.1E-06 kg/kg food.
logKow = 0.74
PBT/vPvB Properties Methyl acrylate does not have PBT or vPvB Properties
SECTION 13. DISPOSAL CONSIDERATIONS
13.1 General information:
Do not allow spilled product and waste water to enter the sewage and open surface water. Avoid
groundwater pollution.
This product, when being disposed of in its unused and uncontaminated state should be treated as a
hazardous waste according to EC Directive 91/689/EEC. Any disposal practices must be in
compliance with all national and provincial laws and any municipal or local by-laws governing
hazardous waste. For used, contaminated and residual materials additional evaluations may be
required. Do not dump into any sewers, on the ground, or into any body of water.
13.2 Waste treatment methods: Must be sent to a suitable incineration plant (thermal neutralization), observing local regulations.
13.3 Contaminated packaging: Uncleaned empties should be disposed of in the same manner as the contents.
For more information please see the relevant exposure scenario in Appendix II of this SDS
SECTION 14. TRANSPORT INFORMATION
Land transport:
ADR/ RID
ID number: UN 1919
Proper shipping name: METHYL ACRYLATE, STABILIZED
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Chemical name Methyl acrylate
Hazard class: 3
Classification code F1
Packing group: PG II
Hazard label: Class 3 (flammable)
Inland waterway transport:
ADN
ID number: UN 1919
Proper shipping name: METHYL ACRYLATE, STABILIZED
Chemical name Methyl acrylate
Hazard class: 3
Classification code F1
Packing group: PG II
Hazard label: Class 3 (flammable)
Marine transport:
IMDG
ID number: UN 1919
Proper shipping name: METHYL ACRYLATE, STABILIZED
Chemical name Methyl acrylate / 2-Propenoic Acid, methyl ester
Hazard class: 3
Packing group: PG II
EMS Number: F-E, S-D
Hazard label: Class 3 (flammable)
Marine pollutant: NO
Air transport:
IATA/ICAO
ID number: UN 1919
Proper shipping name: METHYL ACRYLATE, STABILIZED
Chemical name Methyl acrylate / 2-Propenoic Acid, methyl ester
Hazard class: 3
Packing group: PG II
Hazard label: Class 3 (flammable)
Cargo Packing Instruction: 307
Passenger Packing Instruction: 305
SECTION 15. REGULATORY INFORMATION
REGULATORY
Chemical Safety Report has been performed for Methyl acrylate.
APPENDIX II to the e-SDS: Exposure scenarios.
KEY LITERATURE REFERENCES AND SOURCES
DOCUMENTS, PROVIDED BY ACRYLATE REACH TASK FORCE CONSORTIUM CHEMICAL SAFETY REPORT to Methyl acrylate (CAS 96-33-3).
VERSION: 1.2
DATE CREATED: 16/11/2018
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EU DIRECTIVES
REGULATION (EC) No 1907/2006 OF THE EUROPEAN PARLIAMENT AND OF THE
COUNCIL of 18 December 2006 concerning the Registration, Evaluation, Authorisation and
Restriction of Chemicals (REACH), establishing the European Chemicals Agency, amending
Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission
Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives
91/155/EEC, 93/67/EEC 93/105/EC and 2000/21/EC
Regulation (EC) No 1272/2008 REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification, labelling and
packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and
1999/45/EC, and amending Regulation (EC) No 1907/2006
Regulations: Commission regulation (EU) no 453/2010 of 20 May 2010 amending Regulation (EC)
No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation,
Authorization and Restriction of Chemicals (REACH)
DIRECTIVE 1999/45/EC OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 31
May 1999 concerning the approximation of the laws, regulations and administrative provisions of
the Member States relating to the classification, packaging and labelling of dangerous preparations
Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions
relating to the classification, packaging and labeling of dangerous substances.
COMMISSION DECISION of 16 January 2001 amending Decision 2000/532/EC as regards the list
of wastes (notified under document number (2001/118/EC)
UK REGULATORY REFERENCES
Chemicals (Hazard Information & Packaging) Regulations. The Control of Substances Hazardous
to Health Regulations 1988. Health and Safety at Work Act 1974.
ENVIRONMENTAL LISTING
Control of Pollution Act 1974.
STATUTORY INSTRUMENTS
Notification of New Substances Regulations (NONS) 1993. The Export and Import of Dangerous
Chemicals Regulations 2005 number 928.
APPROVED CODE OF PRACTICE
Classification and Labelling of Substances and Preparations Dangerous for Supply (EU
2001/59/EC). Safety Data Sheets for Substances and Preparations (REACH)
GUIDANCE NOTES
Workplace Exposure Limits EH40. Introduction to Local Exhaust Ventilation HS(G)37. CHIP for
everyone HSG(108).
NATIONAL REGULATIONS
The Chemicals (Hazard Information and Packaging for Supply) Regulations 2002. No. 1689.
Workplace Exposure Limits 2005 (EH40).
The Carriage of Dangerous Goods and use of transportable pressure equipment regulations 2004.
Control of Substances hazardous to health regulations 2002 (as amended).
NATIONAL REGULATIONS (GERMANY)
Major Accident Hazard Legislation 82/501/EWG.
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SECTION 16. OTHER INFORMATION
16.1 Indication of changes
VERSION Date of change Section Description of changes
Version: 1.0 10/10/2011 All Initial SDS.
Version: 1.1 25/07/2014 3; 10 The dossier was updated by the Lead Registrant
1. Section 3. The substance was classified
additional as: Aquatic Chronic 3 (H412: Harmful
to aquatic life with long lasting effects).
2. Section 10. Acute toxicity after inhalation
exposure: LD50 was corrected.
Version: 1.2 16/11/2018 9 Physical and chemical properties were updated.
16.2 Abbreviations and acronyms
ADR
European Agreement concerning the International Carriage of Dangerous Goods by
Road
AGS The German Committee on Hazardous Substances (Ausschuss für Gefahrstoffe –
AGS)
BCF Bioconcentration factor
DFG Germany Research Foundation
DNEL Derived No Effect Level
IMDG International Maritime Dangerous Goods
ICAO-TI Technical Instructions for the Safe Transport of Dangerous Goods by Air
Koc Adsorption coefficient
Kow octanol-water partition coefficient
LC50 Lethal Concentration to 50 % of a test population
LD50 Lethal Dose to 50% of a test population (Median Lethal Dose)
LOAEC Lowest Observable Adverse Effect Concentration
LTEL Long Term Exposure Limit
NIOSH National Institute for Occupational Safety and Health (USА CDC)
NOEC No Observed Effect Concentration
NOAEL No Observed Adverse Effect Level
OECD Organization for Economic Co-operation and Development
OSHA Occupational Safety & Health Administration (USА)
PNEC Predicted No Effect Concentration
PBT Persistent, bioaccumulative, toxic chemical
vPvB Very Persistent, Very Bioaccumulative
RID Regulations concerning the International Carriage of Dangerous Goods by Rail
STEL Short Term Exposure Limit
STOT Specific Target Organ Toxicity
(STOT) RE Repeated Exposure
(STOT) SE Single Exposure
TWA Time Weighted Average
UN United Nations
WGK Wassergefährdungsklasse (German: Water Hazard Class)
16.3 List of ES (exposure scenario) given in Appendix I to the extended SDS:
ES1 Manufacture and distribution
ES2 Polymerization at production sites (IU1)
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ES3 Manufacture of intermediates at production sites (IU2)
ES4 Polymerization at downstream user sites (IU3)
ES5 Manufacture of intermediates at downstream user sites (IU4)
ES6 Use as laboratory reagent (IU5)
IU1: polymerization at production sites
IU2: manufacture of intermediates at production sites
IU3: polymerization at downstream user sites
IU4: manufacture of intermediates at downstream user sites
IU5: use as laboratory reagent
DISCLAIMER
This information is based on our current level of knowledge. This information may be subject to
revision as new knowledge and experience becomes available, and SIBUR makes no warranties and
assumes no liability in connection with any use of this information. Since SIBUR cannot be aware
of all aspects of your business and the impact the REACH Regulation has for your company, SIBUR
strongly encourages you to get familiar with the REACH Regulation in order to comply with its
requirements and timelines.
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Annex I
Relevant identified uses of the substance
Table 1. Uses by workers in industrial settings
Confidential IU number Identified
Use (IU)
name
Substance
supplied to
that use
Use descriptors
Manufacture
and
distribution
as such
(substance
itself)
Process category (PROC):
PROC 1: Use in closed process, no likelihood of exposure
PROC 2: Use in closed, continuous process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 8a: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at non-dedicated facilities
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated
filling line, including weighing)
Market sector by type of chemical product: PC 19: Intermediate
Environmental release category (ERC): ERC 1: Manufacture of substances
Sector of end use (SU): SU 8: Manufacture of bulk, large scale chemicals (including petroleum products)
SU 9: Manufacture of fine chemicals
Subsequent service life relevant for that use?: no
Article category related to subsequent service life (AC):
AC 0: Other: No articles
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Confidential IU number Identified
Use (IU)
name
Substance
supplied to
that use
Use descriptors
1 Polymerizati
on at
production
sites (IU1)
as such
(substance
itself)
Process category (PROC):
PROC 1: Use in closed process, no likelihood of exposure
PROC 2: Use in closed, continuous process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 4: Use in batch and other process (synthesis) where opportunity for exposure
arises
PROC 5: Mixing or blending in batch processes for formulation of preparations and
articles (multistage and/or significant contact)
PROC 8a: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at non-dedicated facilities
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated
filling line, including weighing)
Market sector by type of chemical product:
PC 19: Intermediate
PC 32: Polymer preparations and compounds
Environmental release category (ERC):
ERC 6c: Industrial use of monomers for manufacture of thermo-plastics
ERC 6d: Industrial use of process regulators for polymerisation processes in
production of resins, rubbers, polymers
Sector of end use (SU):
SU 8: Manufacture of bulk, large scale chemicals (including petroleum products)
SU 9: Manufacture of fine chemicals
SU 12: Manufacture of plastics products, including compounding and conversion
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Confidential IU number Identified
Use (IU)
name
Substance
supplied to
that use
Use descriptors
Subsequent service life relevant for that use?: no
Article category related to subsequent service life (AC):
AC 0: Other: No articles
2 Manufacture
of
intermediates
at production
sites
as such
(substance
itself)
Process category (PROC):
PROC 1: Use in closed process, no likelihood of exposure
PROC 2: Use in closed, continuous process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 4: Use in batch and other process (synthesis) where opportunity for exposure
arises
PROC 5: Mixing or blending in batch processes for formulation of preparations and
articles (multistage and/or significant contact)
PROC 8a: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at non-dedicated facilities
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated
filling line, including weighing)
Market sector by type of chemical product:
PC 19: Intermediate
Environmental release category (ERC):
ERC 6a: Industrial use resulting in manufacture of another substance (use of
intermediates)
Sector of end use (SU):
SU 8: Manufacture of bulk, large scale chemicals (including petroleum products)
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Confidential IU number Identified
Use (IU)
name
Substance
supplied to
that use
Use descriptors
SU 9: Manufacture of fine chemicals
Subsequent service life relevant for that use?: no
Article category related to subsequent service life (AC):
AC 0: Other: No article
3 Polymerizati
on at
downstream
user sites
as such
(substance
itself)
Process category (PROC): PROC 1: Use in closed process, no likelihood of exposure
PROC 2: Use in closed, continuous process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 4: Use in batch and other process (synthesis) where opportunity for exposure
arises
PROC 5: Mixing or blending in batch processes for formulation of preparations and
articles (multistage and/or significant contact)
PROC 8a: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at non-dedicated facilities
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated
filling line, including weighing)
Market sector by type of chemical product: PC 19: Intermediate
PC 32: Polymer preparations and compounds
Environmental release category (ERC): ERC 6c: Industrial use of monomers for manufacture of thermo-plastics
ERC 6d: Industrial use of process regulators for polymerisation processes in
production of resins, rubbers, polymers
Sector of end use (SU):
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Confidential IU number Identified
Use (IU)
name
Substance
supplied to
that use
Use descriptors
SU 8: Manufacture of bulk, large scale chemicals (including petroleum products)
SU 9: Manufacture of fine chemicals
SU 12: Manufacture of plastics products, including compounding and conversion
Subsequent service life relevant for that use?: no
Article category related to subsequent service life (AC): AC 0: Other: No article
4 Manufacture
of
intermediates
at
downstream
user sites
as such
(substance
itself)
Process category (PROC): PROC 1: Use in closed process, no likelihood of exposure
PROC 2: Use in closed, continuous process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 4: Use in batch and other process (synthesis) where opportunity for exposure
arises
PROC 5: Mixing or blending in batch processes for formulation of preparations and
articles (multistage and/or significant contact)
PROC 8a: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at non-dedicated facilities
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to
vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated
filling line, including weighing)
Market sector by type of chemical product: PC 19: Intermediate
Environmental release category (ERC): ERC 6a: Industrial use resulting in manufacture of another substance (use of
intermediates)
Sector of end use (SU): SU 8: Manufacture of bulk, large scale chemicals (including petroleum products)
SU 9: Manufacture of fine chemicals
Subsequent service life relevant for that use?: no
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Confidential IU number Identified
Use (IU)
name
Substance
supplied to
that use
Use descriptors
Article category related to subsequent service life (AC): AC 0: Other: No article
5 Use as
laboratory
reagent
as such
(substance
itself)
Process category (PROC): PROC 15: Use as laboratory reagent
Market sector by type of chemical product: PC 19: Intermediate
PC 21: Laboratory chemicals
Environmental release category (ERC): ERC 1: Manufacture of substances
Sector of end use (SU): SU 8: Manufacture of bulk, large scale chemicals (including petroleum products)
SU 9: Manufacture of fine chemicals
SU 24: Scientific research and development
Subsequent service life relevant for that use?: no
Most common technical function of substance (what it does):
- Intermediates
- Laboratory chemicals
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Annex II
1. EXPOSURE ASSESSMENT
General remarks
Introduction and uses
Methyl acrylate (MA) is a chemical intermediate, manufactured and processed almost entirely within
closed systems. Its major use is the production of homo- and co-polymers with other monomers (i.e.,
acrylic acid and its salts, esters, amides, etc.) to produce emulsion polymers. The three major uses of
acrylate esters are: surface coatings, adhesives/sealants and textiles.
The most likely route of human exposure (workers) to methyl acrylate is through inhalation and/or
dermal contact. In industrial settings, ingestion is not an anticipated route of exposure. Worker
exposure can occur in manufacturing facilities, in industrial facilities where the substance is used as
an intermediate, and in industrial facilities where polymerization is conducted.
The ECETOC Targeted Risk Assessment Tool (TRA) version 2.0 was used for the occupational
exposure assessment. Details of the TRA may be found in the ECETOC Technical Report No. 93
(2004), and the accompanying Addendum Technical Report No. 107 (2009), or at
https://www.ecetoc-tra.org/. The assessment of environmental exposure was carried out using
EUSES v2.1. Documentation for EUSES 2.1 may be found at http://ecb.jrc.ec.europa.eu/euses.
The registrant has conducted a mapping of uses within the supply chain. Based on the results of this
mapping and using the Generic Exposure Scenarios as a basis (as developed within the solvent sector,
ESIG/ESVOC), the following uses (as stated in chapter 2) have been identified:
IU1: polymerization at production sites
IU2: manufacture of intermediates at production sites
IU3: polymerization at downstream user sites
IU4: manufacture of intermediates at downstream user sites
IU5: use as laboratory reagent
For these identified uses a number of exposure scenarios have been derived which are
summarized in the table below.
For the occupational scenarios, it is possible that individual manufacturers and/or downstream
users may use and handle methyl acrylate under differing operational conditions, such as indoors
or outdoors and in the presence or absence of local exhaust ventilation. To cover these potential
conditions, 3 scenarios and appropriate risk management measures (when necessary) were
developed for certain TRA Process Categories (PROCs):
1) indoor process without local exhaust ventilation (LEV);
2) indoor process with LEV present; and 3) outdoors (with general dilution ventilation).
Methyl acrylate completely reacts (less than 0.1 wt% remains) during use; therefore, development of
exposure scenarios covering downstream uses (i.e., professional use, consumer use, service life, waste
treatment) are not required and have not been conducted for this assessment.
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ES
no
Linked to
Identified Use
Sector
of Use
(SU)
Life
Cycle
Stage*
Product
Category
(PC)
Process
Category
(PROC)
Article
Category
(AC)
Environmental
Release
Category
(ERC)
Tonnage
(ktonnes)
ES1 Manufacture
and distribution
8, 9 MA 19 1, 2, 3,
8a, 8b, 9
NA ERC1 ES1-E1
3.12E04
ES1-E2
3.12E04
ES1-E3
6.25E04
Total ES1
1.25E05
ES2 Polymerization
at production
sites (IU1)
8, 9, 12 EU 19, 32 1, 2, 3, 4,
5, 8a, 8b,
9
NA ERC6C,
ERC6D
1.24E04
ES3 Manufacture of
intermediates
at production sites (IU2)
8, 9 EU 19 1, 2, 3, 4,
5, 8a, 8b, 9
NA ERC6A 6.22E03
ES4 Polymerization
at downstream
user sites (IU3)
8, 9, 12 EU 19, 32 1, 2, 3, 4,
5, 8a, 8b,
9
NA ERC6C,
ERC6D
7.0E04
ES5 Manufacture of
intermediates
at downstream
user sites (IU4)
8, 9 EU 19 1, 2, 3, 4,
5, 8a, 8b, 9
NA ERC6A 2.33E04
ES6 Use as
laboratory reagent (IU5)
8, 9, 24 EU 19, 21 15 NA ERC1 NA
(included
in ERC1 ES1)
*Life cycle stage: MA = manufacture; FO = formulation; EU = end use; CU = consumer use; SL=
service life; WS = waste stage
For methyl acrylate [MA] a total of four facilities were assumed. In order to facilitate the
parameterization of EUSES to reflect operations in the production facilities analytical samples were
taken for each site with regard to concentration of MA in STP influent and effluent. Samples of the
STP influent and effluent were taken. [Analytical sampling protocol and method attached.] Sampling
in this manner will encompass production and [internal] down stream uses including wet
polymerization and transesterification. Wet polymerization and transesterification down stream uses
external to the three specific production plants were also parameterized within EUSES employing the
measured effluent concentrations. These concentrations assume that risk mitigation measures will be
in place at each external DU production site. These external DUs represent customer use.
Based on the analytical measurements, a value of 0.01 mg.L-1 [10 µg.L-1] was input into EUSES as
the STP effluent concentration for the three production sites and the internal and external DU process
sites. This assumes that the analytical method limit of detection [LOD] was 10 µg.L-1. If MA
concentrations were below the LOD, one-half the LOD concentration could be assumed yielding 5
µg.L-1. Thus the assumption of 10 µg.L-1 would be considered conservative if measured values were
below the LOD.
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METHYL ACRYLATE
μg/l Site 1 Site 2 Site 3 Site 4
Industrial Use Influent Effluent Influent Effluent Influent Effluent Influent Effluent
Manufacture
and Distribution
of Substance
38.6 <1 81 < 1
<1 <1
Polymerization
at Production
Site
30.5 < 1
Polymerization
at Downstream
User Sites
Manufacture of
Intermediates at
Production and
Downstream
User Sites
30.5 < 1
Use as
Laboratory
Reagent
81 < 1
Use of
Preparations
Containing Up
to 21%
Monomer
Other Uses of
Substance as
Intermediate
The following information has been used for the exposure assessments:
Substance Methyl acrylate
CAS no 96-33-3
Substance Volatility (hPa at 20 °C) 90
TRA Volatility Range Medium
Biodegradability Readily biodegradable
Molecular Weight (g/mol) 86.0892
Melting Point (° C) -76.5
Boiling Point (° C) 80.1
Solubility (g/l at 20 °C) 6.0E01
Kow 0.739
Chemical class for Koc-QSAR Esters
Koc L/kg 6.423
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1.1. Exposure scenario 1: Manufacture and distribution
This scenario covers the manufacture and distribution of the bulk substance. Included within this
scenario are material receipt, preparation, reaction, bulk transfer and storage, as well as equipment
cleaning, and associated maintenance activities.
1.1.1. Exposure scenario
Section 1 Exposure Scenario Title
Title Manufacture and distribution
Sector of Use SU8, SU9
Process Category PROC1, PROC2, PROC3, PROC8a, PROC8b, PROC9
Product Category PC19
Article Category n/a
Environmental release
Category
ERC1
Specific environmental
release category
n/a
Processes, tasks, activities
covered
Covers the manufacture and distribution of the substance in the Process Categories
listed above.
Section 2 Operational conditions and risk management measures
Section 2.1 Control of worker exposure
Product characteristics
Physical form of product Liquid
Volatility Medium volatility
Concentration of
substance in product
Up to 100%
Operational conditions
Amounts used Not relevant for this scenario
Frequency and duration of
use
Covers daily exposures up to 8 hours (unless stated differently) [G2].
Human factors not
influenced by risk
management
None identified for this scenario.
Other Operational
Conditions affecting
worker exposure
Assumes activities are at ambient temperature (unless stated differently) [G17].
Assumes a good basic standard of occupational hygiene is implemented [G1].
Since methyl acrylate is a potential skin sensitizer, the use of chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training is required when handling methyl acrylate and
where indicated under the Risk Management Measures (RMMs) for a given scenario. Butyl rubber
gloves with a minimum thickness of 0.7 mm and a chemical specific breakthrough time of >480
minutes are required for these scenarios.
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Risk Management Measures Detailed information on this Exposure Scenario can be found in
appendix A.
Identifier* Contributing Scenarios Process
Categories
Risk Management Measures
ES1-W1 General exposures (closed
systems); Indoors, No LEV
present.
1 Handle substance within a closed system [E47].
ES1-W2 General exposures (closed
systems); With sample
collection; Indoors, No
LEV present.
2 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES1-W3 General exposures (closed
systems); With sample
collection; Indoors, with
LEV present.
2 Handle substance within a closed system [E47].
Provide extract ventilation to points where emissions
occur [E54].
ES1-W4 General exposures (closed
systems); With sample
collection; Outdoors.
2 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 4 hours [OC12]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES1-W5 Use in contained batch
processes;
With sample collection;
Indoors, No LEV present.
3 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES1-W6 Use in contained batch
processes;
With sample collection;
Indoors, with LEV present.
3 Handle substance within a predominantly closed
system provided with extract ventilation [E49].
ES1-W7 Use in contained batch
processes;
With sample collection;
Outdoors
3 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 1 hour [OC11]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES1-W8 Drum/batch transfers; Non-
dedicated facility; Indoors,
No LEV present.
8a Transfer via enclosed lines [E52].; Clear transfer lines
prior to de-coupling [E39].Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES1-W9 Drum/batch transfers; Non-
dedicated facility; Indoors,
with LEV present.
8a Transfer via enclosed lines [E52].; Clear transfer lines
prior to de-coupling [E39].Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES1-W10 Drum/batch transfers; Non-
dedicated facility;
Outdoors.
8a Transfer via enclosed lines [E52].; Clear transfer lines
prior to de-coupling [E39].Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
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respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES1-W11 Drum/batch transfers;
Dedicated facility; Indoors,
No LEV present.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES1-W12 Drum/batch transfers;
Dedicated facility; Indoors,
with LEV present.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES1-W13 Drum/batch transfers;
Dedicated facility;
Outdoors.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES1-W14 Drum and small package
filling;
Indoors, No LEV present.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES1-W15 Drum and small package
filling; Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill points supplied
with local extract ventilation [E51]. Wear chemically
resistant gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES1-W16 Drum and small package
filling; Outdoors.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out operation for more
than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29];
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
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Section 2 Operational conditions and risk management measures
Section 2.2 Control of environmental exposure
Identifier*: Manufacturing Site #1 ES1-E1
Contributing scenario Manufacturing
Environmental Release Category ERC1
Specific ERC -
Assessment scenario IC=3, UC=33
Operational Conditions
Amounts used
Amounts used in the EU (tonnes/year) 3.12E04
Fraction of EU tonnage used in region 1.0
Fraction of main source to local
environment 1
Fraction of substance in end-use products 1
Frequency and duration of use
Type of release Continuous
Emission days (days/year) 300
Environmental factors not influenced by
risk management
Local freshwater dilution factor 10 (default)
Local marine water dilution factor 100 (default)
Other given operational conditions
affecting environmental exposure Not applicable
Risk Management Measures
Conditions and measures related to
municipal sewage treatment plant
E13.20 - Biological treatment – Anaerobic – For soluble
biodegradable contaminants
E13.21 - Biological treatment – Aerobic – For soluble
biodegradable contaminants
E13.23 - Biological treatment - Central Biological Waste
Water Treatment - For soluble biodegradable
contaminants
Estimated substance removal from
wastewater via domestic sewage treatment
(%) 95 %
Conditions and measures related to
external treatment of waste for disposal No application of sludge to soil
Conditions and measures related to
external recovery of waste
Other environmental control measures
additional to above
Dispose of waste cans and containers according to local
regulations.
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
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1.1.2. Exposure estimation
1.1.2.1. Workers exposure
The worker exposure estimates for the activities associated with this use of methyl acrylate have been assessed using ECETOC TRA v2, unless stated differently (see appendix B). Assessment parameter default values: Fugacity: moderate Type of Use; industrial Concentration: > 25 % Local Exhaust Ventilation: indoor scenarios assessed both with, and without LEV Duration of Exposure: > 4 hours/day unless indicated under RMMs Respiratory Protection Equipment: none required unless indicated under RMMs The ECETOC TRA v2 estimates task based exposure. The exposure estimates shown are representative for activities lasting up to 8 hours. Due to the activity based character of this estimation tool, these exposure estimates are thereby also representative for short term activities (e.g., 15 minutes to 1 hour). Therefore no short term inhalatory exposure estimates are calculated nor shown in the table below (indicated by n.a.), since long term (8 hour) estimates already cover short term exposure.
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Identifier Contributing
scenarios
PROC Risk Management Measures Inhalatory exposure
(mg/m3)
Dermal exposure (mg/kg/day) Dermal exposure
(µg/cm2)
Long
term
Acute Long term Acute systemic Acute local
ES1-W1 General exposures
(closed systems);
Indoors, No LEV
present.
1 Handle substance within a closed system
[E47].
0.04 n.a. n.a. n.a. 100
ES1-W2 General exposures
(closed systems);
With sample
collection; Indoors,
No LEV present.
2 Handle substance within a closed system
[E47]. Avoid carrying out operation for
more than 1 hour [OC11] or: Wear a
respirator conforming to EN140 with
Type A/P2 filter or better {PPE29]
7.18 n.a. n.a. n.a. 200
ES1-W3 General exposures
(closed systems);
With sample
collection; Indoors,
with LEV present.
2 Handle substance within a closed system
[E47]. Provide extract ventilation to
points where emissions occur [E54].
3.59 n.a. n.a. n.a. 200
ES1-W4 General exposures
(closed systems);
With sample
collection;
Outdoors.
2 Handle substance within a closed system
[E47]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 4 hours [OC12]
or] or: Wear a respirator conforming to
EN140 with Type A/P2 filter or better
{PPE29]
15.07 n.a. n.a. n.a. 200
ES1-W5 Use in contained
batch processes;
With sample
collection; Indoors,
No LEV present.
3 Handle substance within a closed system
[E47]. Avoid carrying out operation for
more than 1 hour [OC11] or] or: Wear a
respirator conforming to EN140 with
Type A/P2 filter or better {PPE29]
17.94 n.a. n.a. n.a. 100
ES1-W6 Use in contained
batch processes;
3 Handle substance within a
predominantly closed system provided
8.97 n.a. n.a. n.a. 100
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With sample
collection; Indoors,
with LEV present.
with extract ventilation [E49].
ES1-W7 Use in contained
batch processes;
With sample
collection;
Outdoors
3 Handle substance within a closed system
[E47]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 1 hour [OC11]
or: Wear a respirator conforming to
EN140 with Type A/P2 filter or better
{PPE29]
12.56 n.a. n.a. n.a. 100
ES1-W8 Drum/batch
transfers; Non-
dedicated facility;
Indoors, No LEV
present.
8a Transfer via enclosed lines [E52].; Clear
transfer lines prior to de-coupling
[E39].Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear
a respirator conforming to EN140 with
Type A/P2 filter or better {PPE29];
Wear chemically resistant gloves (tested
to EN374) in combination with ‘basic’
employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES1-W9 Drum/batch
transfers; Non-
dedicated facility;
Indoors, with LEV
present.
8a Transfer via enclosed lines [E52].; Clear
transfer lines prior to de-coupling
[E39].Provide extract ventilation to
material transfer points and other
openings [E82].Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
17.94 n.a. n.a. n.a. 100
ES1-W10 Drum/batch
transfers; Non-
dedicated facility;
Outdoors.
8a Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling
[E39].Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 15 minutes
[OC10] or: Wear a respirator
12.56 n.a. n.a. n.a. 100
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conforming to EN140 with Type A/P2
filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
ES1-W11 Drum/batch
transfers;
Dedicated facility;
Indoors, No LEV
present.
8b Transfer via enclosed lines [E52].; Clear
transfer lines prior to de-coupling
[E39].Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear
a respirator conforming to EN140 with
Type A/P2 filter or better {PPE29];
Wear chemically resistant gloves (tested
to EN374) in combination with ‘basic’
employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES1-W12 Drum/batch
transfers;
Dedicated facility;
Indoors, with LEV
present.
8b Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling [E39].
Provide extract ventilation to material
transfer points and other openings
[E82].Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
5.38 n.a. n.a. n.a. 100
ES1-W13 Drum/batch
transfers;
Dedicated facility;
Outdoors.
8b Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling [E39].
Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear
a respirator conforming to EN140 with
Type A/P2 filter or better {PPE29];
Wear chemically resistant gloves (tested
to EN374) in combination with ‘basic’
employee training [PPE16].
12.56 n.a. n.a. n.a. 100
ES1-W14 Drum and small 9 Use in semi-automated and 17.94 n.a. n.a. n.a. 100
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package filling;
Indoors, No LEV
present.
predominantly enclosed filling lines
[E41]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear
a respirator conforming to EN140 with
Type A/P2 filter or better {PPE29];
Wear chemically resistant gloves (tested
to EN374) in combination with ‘basic’
employee training [PPE16].
ES1-W15 Drum and small
package filling;
Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill
points supplied with local extract
ventilation [E51]. Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
17.94 n.a. n.a. n.a. 100
ES1-W16 Drum and small
package filling;
Outdoors.
9 Use in semi-automated and
predominantly enclosed filling lines
[E41]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 15 minutes
[OC10] or: Wear a respirator
conforming to EN140 with Type
A/P2 filter or better {PPE29];
Wear chemically resistant gloves (tested
to EN374) in combination with ‘basic’
employee training [PPE16].
12.56 n.a. n.a. n.a. 100
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1.1.2.2. Consumer exposure
Not applicable.
1.1.2.3. Indirect exposure of humans via the environment (oral)
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible as reflected by the values below.
LOCAL ES1-E1 ES1-E2 ES1-E3
local Concentration in wet fish kg/kgwwt 3.18E-09 3.18E-09 1.23E-09
local concentration in drinking water kg/m3 8.13E-05 8.13E-05 9.55E-06
local concentration in meat (wet weight) kg/kgwwt 3.34E-11 3.34E-11 3.59E-12
local concentration in milk (wet weight) kg/kgwwt 3.34E-10 3.34E-10 3.59E-11
1.1.2.4. Environmental exposure
Identifier ES1-E1
Manufacture Site #1 The exposure scenario is based A&B tables
IC= 3 and UC= 33
Release fraction to air from process 1.0E-02
Release fraction to wastewater from
process 3.0E-03
Release fraction to soil from process
(regional only) 0
Local release to air (kg/d) 1.04E03
Local release to sewage (kg/d) 3.65E02
Local release to soil (kg/d) 0
Fraction remaining in water after STP
treatment (Fwater) 3.25E-02
Removal in STP (fraction) 9.50E-01
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1.1.2.4.1 Predicted exposure concentrations in aquatic the STP and in aquatic compartments
(freshwater, seawater and sediment)
Local Concentration, Compartment: STP and
aquatic unit ES1-E1
Local PEC in surface water during emission
episode (dissolved) mg/L 1.18E-03
Annual average local PEC in surface water
(dissolved) mg/L 1.01E-03
Local PEC in fresh water sediment during
emission episode
mg/kg
dwt 5.03E-03
Local PEC in sea water during emission episode mg/L 1.22E-04
Annual average local PEC in sea water (dissolved) mg/L 1.04E-04
Local PEC in marine sediment during emission
episode
mg/kg
dwt 5.17E-04
PEC for microorganisms in STP mg/L 1.00E-02
Comments
1.1.2.4.2 Predicted exposure concentration in soils
Local Concentration, Compartment: soil unit ES1-E1
Local PEC in agricultural soil, averaged over 30
days
mg/kg
dwt 2.13E-02
Local PEC agricultural soil, averaged over 180
days
mg/kg
dwt 2.13E-02
Local PEC in grass land, averaged over 180 days
mg.kg
dwt 3.93E-02
Comments
1.1.2.4.3 Predicted exposure concentration in the atmospheric compartment
Local Concentration,
Compartment: air unit ES1-E1
Annual average local PEC in air
(total) kg/m
3 2.38E-07
Comments
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1.1.2.4.4 Predicted exposure concentration in food for secondary poisoning
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible. The table below illustrates the negligible PECs as a function of secondary
poisoning.
Secondary poisoning unit ES1-E1
Conc. in fish for secondary poisoning in freshwater
environment mg/kgwwt 1.88E-03
Conc. in fish for secondary poisoning in marine
environment mg/kgwwt 1.99E-04
Conc. in fish-eating predator for marine top predators mg/kgwwt 9.52E-05
Conc. in earthworms for secondary poisoning mg/kgwwt 3.41E-02
Comments
Manufacturing Site #2
Section 2
Operational conditions and risk management
measures
Section 2.2 Control of environmental exposure
Identifier*: Manufacture Site #2 ES1-E2
Contributing scenario Manufacturing
Environmental Release Category ERC1
Specific ERC -
Assessment scenario IC=3, UC=33
Operational Conditions
Amounts used
Amounts used in the EU (tonnes/year) 3.12E04
Fraction of EU tonnage used in region 1.0
Fraction of main source to local
environment 1
Fraction of substance in end-use products 1
Frequency and duration of use
Type of release Continuous
Emission days (days/year) 300
Environmental factors not influenced by
risk management
Local freshwater dilution factor 10 (default)
Local marine water dilution factor 100 (default)
Other given operational conditions
affecting environmental exposure Not applicable
Risk Management Measures
Conditions and measures related to
municipal sewage treatment plant
E13.20 - Biological treatment – Anaerobic – For
soluble biodegradable contaminants
E13.21 - Biological treatment – Aerobic – For
soluble biodegradable contaminants
E13.23 - Biological treatment - Central Biological
Waste Water Treatment - For soluble
biodegradable contaminants
Estimated substance removal from
wastewater via domestic sewage treatment
(%) 95 %
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Conditions and measures related to
external treatment of waste for disposal No application of sludge to soil
Conditions and measures related to
external recovery of waste
Other environmental control measures
additional to above
Dispose of waste cans and containers according to
local regulations.
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
1.1.2.5. Environmental exposure
Identifier ES1-E2
Manufacture Site #2
The exposure scenario is based A&B tables
IC= 3 and UC= 33
Release fraction to air from process 1.0E-02
Release fraction to wastewater from
process 3.0E-03
Release fraction to soil from process
(regional only) 0
Local release to air (kg/d) 1.04E03
Local release to sewage (kg/d) 3.65E02
Local release to soil (kg/d) 0
Fraction remaining in water after STP
treatement (Fwater) 3.25E-02
Removal in STP (fraction) 9.5E-01
1.1.2.5.1 Predicted exposure concentrations in aquatic the STP and in the aquatic compartments
(freshwater, seawater and sediments)
Local Concentration, Compartment: STP and aquatic unit ES1-E2
Local PEC in surface water during emission episode
(dissolved) mg/L 1.18E-03
Annual average local PEC in surface water (dissolved) mg/L 1.01E-03
Local PEC in fresh water sediment during emission episode mg/kg dwt 5.03E-03
Local PEC in sea water during emission episode mg/L 1.22E-04
Annual average local PEC in sea water (dissolved) mg/L 1.04E-04
Local PEC in marine sediment during emission episode mg/kg dwt 5.17E-04
PEC for microorganisms in STP mg/L 1.00E-02
Comments
1.1.2.5.2 Predicted exposure concentration in soils
Local Concentration, Compartment: soil unit ES1-E2
Local PEC in agricultural soil, averaged over 30 days mg/kg dwt 2.13E-02
Local PEC agricultural soil, averaged over 180 days mg/kg dwt 2.13E-02
Local PEC in grass land, averaged over 180 days mg.kg dwt 3.93E-02
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1.1.2.5.3 Predicted exposure concentration in the atmospheric compartment
Local Concentration,
Compartment: air unit ES1-E2
Annual average local PEC in air
(total) kg/m
3 2.38E-07
Comments
1.1.2.5.4 Predicted exposure concentration in food for secondary poisoning
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible. The table below illustrates the negligible PECs as a function of secondary
poisoning.
Secondary poisoning unit ES1-E2
Conc. in fish for secondary poisoning in freshwater
environment mg/kgwwt 1.88E-03
Conc. in fish for secondary poisoning in marine
environment mg/kgwwt 1.99E-04
Conc. in fish-eating predator for marine top predators mg/kgwwt 9.52E-05
Conc. in earthworms for secondary poisoning mg/kgwwt 3.41E-02
Comments
Manufacturing Site #3
Section 2 Operational conditions and risk management measures
Section 2.2 Control of environmental exposure
Identifier*: Manufacture Site #3 ES1-E3
Contributing scenario Manufacturing
Environmental Release Category ERC1
Specific ERC -
Assessment scenario IC=3, UC=33
Operational Conditions
Amounts used
Amounts used in the EU (tonnes/year) 6.25E04
Fraction of EU tonnage used in region 1.0
Fraction of main source to local
environment
1
Fraction of substance in end-use products 1
Frequency and duration of use
Type of release Continuous
Emission days (days/year) 300
Environmental factors not influenced by
risk management
Local freshwater dilution factor 10 (default)
Local marine water dilution factor 100 (default)
Other given operational conditions
affecting environmental exposure
Not applicable
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Risk Management Measures
Conditions and measures related to
municipal sewage treatment plant
E13.20 - Biological treatment – Anaerobic – For soluble
biodegradable contaminants
E13.21 - Biological treatment – Aerobic – For soluble
biodegradable contaminants
E13.23 - Biological treatment - Central Biological Waste
Water Treatment - For soluble biodegradable
contaminants
Estimated substance removal from
wastewater via domestic sewage treatment
(%)
95 %
Conditions and measures related to
external treatment of waste for disposal
No application of sludge to soil
Conditions and measures related to
external recovery of waste
Other environmental control measures
additional to above
Dispose of waste cans and containers according to local
regulations.
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
1.1.2.6. Environmental exposure
Identifier ES1-E3
Manufacture Site #3 The exposure scenario is based A&B tables
IC= 3 and UC= 33
Release fraction to air from process 1.0E-02
Release fraction to wastewater from process 3.0E-03
Release fraction to soil from process (regional
only) 0
Local release to air (kg/d) 1.10E02
Local release to sewage (kg/d) 7.29E02
Local release to soil (kg/d) 0
Fraction remaining in water after STP treatement
(Fwater) 3.25E-02
Removal in STP (fraction) 9.5E-01
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1.1.2.6.1 Predicted exposure concentrations in aquatic the STP and in the aquatic compartments
(freshwater, seawater and sediments)
Local Concentration, Compartment: STP and aquatic unit ES1-E3
Local PEC in surface water during emission episode
(dissolved) mg/L 4.35E-04
Annual average local PEC in surface water (dissolved) mg/L 3.90E-04
Local PEC in fresh water sediment during emission
episode mg/kg dwt 1.84E-03
Local PEC in sea water during emission episode mg/L 1.22E-04
Annual average local PEC in sea water (dissolved) mg/L 1.04E-04
Local PEC in marine sediment during emission episode mg/kg dwt 5.17E-04
PEC for microorganisms in STP mg/L 1.00E-02
Comments
1.1.2.6.2 Predicted exposure concentration in soils
Local Concentration, Compartment: soil unit ES1-E3
Local PEC in agricultural soil, averaged over 30 days mg/kg dwt 2.50E-03
Local PEC agricultural soil, averaged over 180 days mg/kg dwt 2.50E-03
Local PEC in grass land, averaged over 180 days mg.kg dwt 8.06E-03
Comments
1.1.2.6.3 Predicted exposure concentration in the atmospheric compartment
Local Concentration,
Compartment: air unit ES1-E3
Annual average local PEC in air
(total) kg/m
3 2.53E-08
Comments
1.1.2.6.4 Predicted exposure concentration in food for secondary poisoning
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible. The table below illustrates the negligible PECs as a function of secondary
poisoning.
Secondary poisoning unit ES1-E3
Conc. in fish for secondary poisoning in freshwater
environment mg/kgwwt 9.08E-04
Conc. in fish for secondary poisoning in marine
environment mg/kgwwt 1.99E-04
Conc. in fish-eating predator for marine toppredators mg/kgwwt 9.52E-05
Conc. in earthworms for secondary poisoning mg/kgwwt 4.02E-04
Comments
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1.2. Exposure scenario 2: Polymerization at production sites
This scenario covers the use of methyl acrylate as an intermediate or monomer in the production of
polymers and resins at production sites (including material receipt, preparation, mixing and reaction,
bulk transfer and storage, as well as equipment cleaning and maintenance. This scenario covers both
wet and dry polymerization processes.
1.2.1. Exposure scenario
Section 1 Exposure Scenario Title
Title Polymerization at production sites
Sector of Use SU8, SU9, SU12
Process Category PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9
Product Category PC19, PC32
Article Category n/a
Environmental release
Category
ERC6C, ERC6D
Specific environmental
release category
n/a
Processes, tasks, activities
covered
Covers the polymerization at production sites for the Process Categories listed
above.
Section 2 Operational conditions and risk management measures
Section 2.1 Control of worker exposure
Product characteristics
Physical form of product Liquid
Volatility Medium volatility
Concentration of
substance in product
Up to 100%
Operational conditions
Amounts used Not relevant for this scenario
Frequency and duration of
use
Covers daily exposures up to 8 hours (unless stated differently) [G2].
Human factors not
influenced by risk
management
None identified for this scenario.
Other Operational
Conditions affecting
worker exposure
Assumes activities are at ambient temperature (unless stated differently) [G17];
Assumes a good basic standard of occupational hygiene is implemented [G1].
Since methyl acrylate is a potential skin sensitizer, the use of chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training is required when handling methyl acrylate and
where indicated under the Risk Management Measures (RMMs) for a given scenario. Butyl rubber
gloves with a minimum thickness of 0.7 mm and a chemical specific breakthrough time of >480
minutes are required for these scenarios.
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Risk Management Measures Detailed information on this Exposure Scenario can be found in
appendix A.
Identifier* Contributing Scenarios Process
Categories
Risk Management Measures
ES2-W1 General exposures (closed
systems); Indoors, No LEV
present.
1 Handle substance within a closed system [E47].
ES2-W2 General exposures (closed
systems); With sample
collection; Indoors, No
LEV present.
2 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES2-W3 General exposures (closed
systems); With sample
collection; Indoors, with
LEV present.
2 Handle substance within a closed system [E47].
Provide extract ventilation to points where emissions
occur [E54].
ES2-W4 General exposures (closed
systems); With sample
collection; Outdoors.
2 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 4 hours [OC12]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES2-W5 Use in contained batch
processes;
With sample collection;
Indoors, No LEV present.
3 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES2-W6 Use in contained batch
processes;
With sample collection;
Indoors, with LEV present.
3 Handle substance within a predominantly closed
system provided with extract ventilation [E49].
ES2-W7 Use in contained batch
processes;
With sample collection;
Outdoors
3 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 1 hour [OC11]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES2-W8 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No
LEV present.
4 Avoid carrying out operation for more than 1 hour
[OC11] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES2-W9 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with
LEV present.
4 Provide extract ventilation to material transfer points
and other openings [E82].Wear chemically resistant
gloves (tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES2-W10 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
4 Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 1 hour [OC11]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES2-W11 General exposures; Batch 5 Avoid carrying out operation for more than 15
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process; Indoors, No LEV
present.
minutes [OC10] or: Wear a respirator conforming to
EN140 with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES2-W12 General exposures; Batch
process; Indoors, with LEV
present.
5 Provide extract ventilation to points where emissions
occur [E54]. Wear chemically resistant gloves (tested
to EN374) in combination with ‘basic’ employee
training [PPE16].
ES2-W13 General exposures; Batch
process; Outdoors
5 Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES2-W14 Drum/batch transfers; Non-
dedicated facility; Indoors,
No LEV present.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES2-W15 Drum/batch transfers; Non-
dedicated facility; Indoors,
with LEV present.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES2-W16 Drum/batch transfers; Non-
dedicated facility;
Outdoors.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES2-W17 Drum/batch transfers;
Dedicated facility; Indoors,
No LEV present.
8b Transfer via enclosed lines [E52].; Clear transfer lines
prior to de-coupling [E39].Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES2-W18 Drum/batch transfers;
Dedicated facility; Indoors,
with LEV present.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES2-W1 Drum/batch transfers;
Dedicated facility;
Outdoors.
8b Transfer via enclosed lines [E52].; Clear transfer lines
prior to de-coupling [E39]. Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
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operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES2-W20 Drum and small package
filling; Indoors, No LEV
present.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES2-W21 Drum and small package
filling; Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill points supplied
with local extract ventilation [E51]. Wear chemically
resistant gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES2-W22 Drum and small package
filling; Outdoors.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out operation for more
than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29];
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
Section 2 Operational conditions and risk management measures
Section 2.2 Control of environmental exposure
Identifier*: Polymerization at Production
Sites ES2-E1
Contributing scenario Industrial Use
Environmental Release Category ERC 6C, ERC 6D
Specific ERC -
Assessment scenario IC=3, UC=33
Operational Conditions
Amounts used
Amounts used in the EU (tonnes/year) 1.24E04
Fraction of EU tonnage used in region 1.0
Fraction of main source to local
environment 0.33
Fraction of substance in end-use products 1
Frequency and duration of use
Type of release Continuous
Emission days (days/year) 300
Environmental factors not influenced by
risk management
Local freshwater dilution factor 10 (default)
Local marine water dilution factor 100 (default)
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Section 2 Operational conditions and risk management measures
Other given operational conditions
affecting environmental exposure Not applicable
Risk Management Measures
Conditions and measures related to
municipal sewage treatment plant
E13.20 - Biological treatment – Anaerobic – For soluble
biodegradable contaminants
E13.21 - Biological treatment – Aerobic – For soluble
biodegradable contaminants
E13.23 - Biological treatment - Central Biological Waste
Water Treatment - For soluble biodegradable
contaminants
Estimated substance removal from
wastewater via domestic sewage treatment
(%) 95 %
Conditions and measures related to
external treatment of waste for disposal No application of sludge to soil
Conditions and measures related to
external recovery of waste
Other environmental control measures
additional to above
Dispose of waste cans and containers according to local
regulations.
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
1.2.2. Exposure estimation
1.2.2.1. Workers exposure
The worker exposure estimates for the activities associated with this use of methyl acrylate have been assessed using ECETOC TRA v2, unless stated differently (see appendix B). Assessment parameter default values: Fugacity: moderate Type of Use; industrial Concentration: > 25 % Local Exhaust Ventilation: indoor scenarios assessed both with and without LEV Duration of Exposure: > 4 hours/day unless indicated under RMMs Respiratory Protection Equipment: none required unless indicated under RMMs The ECETOC TRA v2 estimates task based exposure. The exposure estimates shown are representative for activities lasting up to 8 hours. Due to the activity based character of this estimation tool, these exposure estimates are thereby also representative for short term activities (e.g., 15 minutes to 1 hour). Therefore no short term inhalatory exposure estimates are calculated nor shown in the table below (indicated by n.a.), since long term (8 hour) estimates already cover short term exposure.
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory
exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic Acute local
ES2-W1 General exposures (closed
systems); Indoors, No LEV
present.
1 Handle substance within a closed system
[E47].
0.04 n.a. n.a. n.a. 100
ES2-W2 General exposures (closed
systems); With sample
collection; Indoors, No LEV
present.
2 Handle substance within a closed system
[E47]. Avoid carrying out operation for
more than 1 hour [OC11] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
7.18 n.a. n.a. n.a. 200
ES2-W3 General exposures (closed
systems); With sample
collection; Indoors, with
LEV present.
2 Handle substance within a closed system
[E47]. Provide extract ventilation to points
where emissions occur [E54].
3.59 n.a. n.a. n.a. 200
ES2-W4 General exposures (closed
systems); With sample
collection; Outdoors.
2 Handle substance within a closed system
[E47]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 4 hours [OC12] or:
Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]
15.07 n.a. n.a. n.a. 200
ES2-W5 Use in contained batch
processes;
With sample collection;
Indoors, No LEV present.
3 Handle substance within a closed system
[E47]. Avoid carrying out operation for
more than 1 hour [OC11] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
17.94 n.a. n.a. n.a. 100
ES2-W6 Use in contained batch
processes;
With sample collection;
3 Handle substance within a predominantly
closed system provided with extract
ventilation [E49].
8.97 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory
exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic Acute local
Indoors, with LEV present.
ES2-W7 Use in contained batch
processes;
With sample collection;
Outdoors
3 Handle substance within a closed system
[E47]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]
12.56 n.a. n.a. n.a. 100
ES2-W8 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No LEV
present.
4 Avoid carrying out operation for more than
1 hour [OC11] or: Wear a respirator
conforming to EN140 with Type A/P2
filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
14.35 n.a. n.a. n.a. 100
ES2-W9 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with
LEV present.
4 Provide extract ventilation to material
transfer points and other openings
[E82].Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
7.18 n.a. n.a. n.a. 100
ES2-W10 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
4 Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for
more than 1 hour [OC11] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
10.05 n.a. n.a. n.a. 100
ES2-W11 General exposures; Batch 5 Avoid carrying out operation for more than 17.94 n.a. n.a. n.a. 200
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory
exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic Acute local
process; Indoors, No LEV
present.
15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2
filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
ES2-W12 General exposures; Batch
process; Indoors, with LEV
present.
5 Provide extract ventilation to points where
emissions occur [E54]. Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
17.94 n.a. n.a. n.a. 200
ES2-W13 General exposures; Batch
process; Outdoors
5 Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
12.56 n.a. n.a. n.a. 200
ES2-W14 Drum/batch transfers; Non-
dedicated facility; Indoors,
No LEV present.
8a Transfer via enclosed lines [E52].; Clear
transfer lines prior to de-coupling
[E39].Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
17.94 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory
exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic Acute local
ES2-W15 Drum/batch transfers; Non-
dedicated facility; Indoors,
with LEV present.
8a Transfer via enclosed lines [E52].; Clear
transfer lines prior to de-coupling
[E39].Provide extract ventilation to
material transfer points and other openings
[E82].Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES2-W16 Drum/batch transfers; Non-
dedicated facility; Outdoors.
8a Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling
[E39].Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10]
or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29];
Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
12.56 n.a. n.a. n.a. 100
ES2-W17 Drum/batch transfers;
Dedicated facility; Indoors,
No LEV present.
8b Transfer via enclosed lines [E52].; Clear
transfer lines prior to de-coupling
[E39].Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES2-W18 Drum/batch transfers;
Dedicated facility; Indoors,
8b Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling [E39].
5.38 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory
exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic Acute local
with LEV present.
Provide extract ventilation to material
transfer points and other openings
[E82].Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES2-W19 Drum/batch transfers;
Dedicated facility; Outdoors.
8b Transfer via enclosed lines [E52].; Clear
transfer lines prior to de-coupling [E39].
Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
12.56 n.a. n.a. n.a. 100
ES2-W20 Drum and small package
filling; Indoors, No LEV
present.
9 Use in semi-automated and predominantly
enclosed filling lines [E41]. Avoid carrying
out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming
to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES2-W21 Drum and small package
filling; Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill points
supplied with local extract ventilation
[E51]. Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
17.94 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory
exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic Acute local
ES2-W22 Drum and small package
filling; Outdoors.
9 Use in semi-automated and predominantly
enclosed filling lines [E41]. Ensure
operation is undertaken outdoors [E69].
Avoid carrying out operation for more than
15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type
A/P2 filter or better {PPE29];
Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
12.56 n.a. n.a. n.a. 100
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1.2.2.2. Consumer exposure
Not applicable.
1.2.2.3. Indirect exposure of humans via the environment (oral)
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible as reflected by the values below.
LOCAL ES2-E1
local Concentration in wet fish kg/kgwwt 3.18E-09
local concentration in drinking water kg/m3 1.13E-06
local concentration in meat (wet weight) kg/kgwwt 4.64E-13
local concentration in milk (wet weight) kg/kgwwt 4.64E-12
1.2.2.4. Environmental exposure
Identifier ES2-E1
Polymerization at Production Sites The exposure scenario is based A&B tables
IC= 3 and UC= 33
Release fraction to air from process 1.0E-03
Release fraction to wastewater from
process 5.0E-04
Release fraction to soil from process
(regional only) 0
Local release to air (kg/d) 13.7
Local release to sewage (kg/d) 6.84
Local release to soil (kg/d) 0
Fraction remaining in water after STP
treatement (Fwater) 3.25E-02
Removal in STP (fraction) 9.5E-01
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1.2.2.4.1 Predicted exposure concentrations in aquatic the STP and in the aquatic compartments
(freshwater, seawater and sediments)
Local Concentration, Compartment: STP and aquatic unit ES2-E1
Local PEC in surface water during emission episode
(dissolved) mg/L 1.18E-03
Annual average local PEC in surface water (dissolved) mg/L 1.01E-03
Local PEC in fresh water sediment during emission
episode mg/kg dwt 5.03E-03
Local PEC in sea water during emission episode mg/L 1.22E-04
Annual average local PEC in sea water (dissolved) mg/L 1.04E-04
Local PEC in marine sediment during emission episode mg/kg dwt 5.17E-04
PEC for microorganisms in STP mg/L 1.00E-02
Comments
1.2.2.4.2 Predicted exposure concentration in soils
Local Concentration, Compartment: soil unit ES2-E1
Local PEC in agricultural soil, averaged over 30 days mg/kg dwt 2.96E-04
Local PEC agricultural soil, averaged over 180 days mg/kg dwt 2.96E-04
Local PEC in grass land, averaged over 180 days mg.kg dwt 6.01E-04
Comments
1.2.2.4.3 Predicted exposure concentration in the atmospheric compartment
Local Concentration,
Compartment: air unit ES2-E1
Annual average local PEC in air
(total) kg/m
3 3.30E-09
Comments
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1.2.2.4.4 Predicted exposure concentration in food for secondary poisoning
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible. The table below illustrates the negligible PECs as a function of secondary
poisoning.
Secondary poisoning unit ES2-E1
Conc. in fish for secondary poisoning in freshwater
environment mg/kgwwt 1.88E-03
Conc. in fish for secondary poisoning in marine
environment mg/kgwwt 1.99E-04
Conc. in fish-eating predator for marine toppredators mg/kgwwt 9.52E-05
Conc. in earthworms for secondary poisoning mg/kgwwt 4.97E-04
Comments
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1.3. Exposure scenario 3: Manufacture of intermediates at production
sites
This scenario covers the use of methyl acrylate as a chemical intermediate in monomer synthesis
(transesterification or functionalisation) at production sites.
1.3.1. Exposure scenario
Section 1 Exposure Scenario Title
Title Manufacture of intermediates at production sites
Sector of Use SU8, SU9
Process Category PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9
Product Category PC19
Article Category n/a
Environmental release
Category
ERC6A
Specific environmental
release category
n/a
Processes, tasks, activities
covered
Covers the manufacture of intermediates at production sites for the Process
Categories listed above.
Section 2 Operational conditions and risk management measures
Section 2.1 Control of worker exposure
Product characteristics
Physical form of product Liquid
Volatility Medium volatility
Concentration of
substance in product
Up to 100%
Operational conditions
Amounts used Not relevant for this scenario
Frequency and duration of
use
Covers daily exposures up to 8 hours (unless stated differently) [G2].
Human factors not
influenced by risk
management
None identified for this scenario.
Other Operational
Conditions affecting
worker exposure
Assumes activities are at ambient temperature (unless stated differently) [G17].;
Assumes a good basic standard of occupational hygiene is implemented [G1].
Since methyl acrylate is a potential skin sensitizer, the use of chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training is required when handling methyl acrylate and
where indicated under the Risk Management Measures (RMMs) for a given scenario. Butyl rubber
gloves with a minimum thickness of 0.7 mm and a chemical specific breakthrough time of >480
minutes are required for these scenarios.
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Risk Management Measures Detailed information on this Exposure Scenario can be found in
appendix A.
Identifier* Contributing Scenarios Process
Categories
Risk Management Measures
ES3-W1 General exposures (closed
systems); Indoors, No
LEV present.
1 Handle substance within a closed system [E47].
ES3-W2 General exposures (closed
systems); With sample
collection; Indoors, No
LEV present.
2 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES3-W3 General exposures (closed
systems); With sample
collection; Indoors, with
LEV present.
2 Handle substance within a closed system [E47].
Provide extract ventilation to points where emissions
occur [E54].
ES3-W4 General exposures (closed
systems); With sample
collection; Outdoors.
2 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 4 hours [OC12]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES3-W5 Use in contained batch
processes;
With sample collection;
Indoors, No LEV present.
3 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES3-W6 Use in contained batch
processes;
With sample collection;
Indoors, with LEV present.
3 Handle substance within a predominantly closed
system provided with extract ventilation [E49].
ES3-W7 Use in contained batch
processes;
With sample collection;
Outdoors
3 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES3-W8 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No
LEV present.
4 Avoid carrying out operation for more than 1 hour
[OC11] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES3-W9 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with
LEV present.
4 Provide extract ventilation to material transfer points
and other openings [E82].Wear chemically resistant
gloves (tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES3-W10 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
4 Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES3-W11 General exposures; Batch 5 Avoid carrying out operation for more than 15 minutes
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process; Indoors, No LEV
present.
[OC10] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES3-W12 General exposures; Batch
process; Indoors, with
LEV present.
5 Provide extract ventilation to points where emissions
occur [E54]. Wear chemically resistant gloves (tested
to EN374) in combination with ‘basic’ employee
training [PPE16].
ES3-W13 General exposures; Batch
process; Outdoors
5 Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES3-W14 Drum/batch transfers;
Non-dedicated facility;
Indoors, No LEV present.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES3-W15 Drum/batch transfers;
Non-dedicated facility;
Indoors, with LEV present.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES3-W16 Drum/batch transfers;
Non-dedicated facility;
Outdoors.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES3-W17 Drum/batch transfers;
Dedicated facility;
Indoors, No LEV present.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES3-W18 Drum/batch transfers;
Dedicated facility;
Indoors, with LEV present.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES3-W19 Drum/batch transfers;
Dedicated facility;
Outdoors.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
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operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES3-W20 Drum and small package
filling; Indoors, No LEV
present.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES3-W21 Drum and small package
filling; Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill points supplied
with local extract ventilation [E51]. Wear chemically
resistant gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES3-W22 Drum and small package
filling; Outdoors.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out operation for more
than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29];
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
Section 2 Operational conditions and risk management measures
Section 2.2 Control of environmental exposure
Identifier*: Manufacture of Intermediates
at Production Sites ES3-E1
Contributing scenario Industrial Use
Environmental Release Category ERC 6A
Specific ERC -
Assessment scenario IC=3, UC=33
Operational Conditions
Amounts used
Amounts used in the EU (tonnes/year) 6.22E03
Fraction of EU tonnage used in region 1.0
Fraction of main source to local
environment 0.33
Fraction of substance in end-use products 1
Frequency and duration of use
Type of release Continuous
Emission days (days/year) 300
Environmental factors not influenced by
risk management
Local freshwater dilution factor 10 (default)
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Section 2 Operational conditions and risk management measures
Local marine water dilution factor 100 (default)
Other given operational conditions
affecting environmental exposure Not applicable
Risk Management Measures
Conditions and measures related to
municipal sewage treatment plant
E13.20 - Biological treatment – Anaerobic – For soluble
biodegradable contaminants
E13.21 - Biological treatment – Aerobic – For soluble
biodegradable contaminants
E13.23 - Biological treatment - Central Biological Waste
Water Treatment - For soluble biodegradable
contaminants
Estimated substance removal from
wastewater via domestic sewage treatment
(%) 95 %
Conditions and measures related to
external treatment of waste for disposal No application of sludge to soil
Conditions and measures related to
external recovery of waste
Other environmental control measures
additional to above
Dispose of waste cans and containers according to local
regulations.
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
1.3.2. Exposure estimation
1.3.2.1. Workers exposure
The worker exposure estimates for the activities associated with this use of methyl acrylate have been assessed using ECETOC TRA v2, unless stated differently (see appendix B). Assessment parameter default values: Fugacity: moderate Type of Use; industrial Concentration: > 25 % Local Exhaust Ventilation: indoor scenarios assessed both with and without LEV Duration of Exposure: > 4 hours/day unless indicated under RMMs Respiratory Protection Equipment: none required unless indicated under RMMs The ECETOC TRA v2 estimates task based exposure. The exposure estimates shown are representative for activities lasting up to 8 hours. Due to the activity based character of this estimation tool, these exposure estimates are thereby also representative for short term activities (e.g., 15 minutes to 1 hour). Therefore no short term inhalatory exposure estimates are calculated nor shown in the table below (indicated by n.a.), since long term (8 hour) estimates already cover short term exposure.
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long term Acute Long term Acute
systemic
Acute local
ES3-W1 General exposures
(closed systems);
Indoors, No LEV
present.
1 Handle substance within a closed system
[E47].
0.04 n.a. n.a. n.a. 100
ES3-W2 General exposures
(closed systems); With
sample collection;
Indoors, No LEV
present.
2 Handle substance within a closed system
[E47]. Avoid carrying out operation for more
than 1 hour [OC11] or: Wear a respirator
conforming to EN140 with Type A/P2 filter
or better {PPE29]
7.18 n.a. n.a. n.a. 200
ES3-W3 General exposures
(closed systems); With
sample collection;
Indoors, with LEV
present.
2 Handle substance within a closed system
[E47]. Provide extract ventilation to points
where emissions occur [E54].
3.59 n.a. n.a. n.a. 200
ES3-W4 General exposures
(closed systems); With
sample collection;
Outdoors.
2 Handle substance within a closed system
[E47]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out operation
for more than 4 hours [OC12] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
15.07 n.a. n.a. n.a. 200
ES3-W5 Use in contained batch
processes;
With sample
collection; Indoors, No
LEV present.
3 Handle substance within a closed system
[E47]. Avoid carrying out operation for more
than 1 hour [OC11] or: Wear a respirator
conforming to EN140 with Type A/P2 filter
or better {PPE29]
17.94 n.a. n.a. n.a. 100
ES3-W6 Use in contained batch
processes;
With sample
3 Handle substance within a predominantly
closed system provided with extract
8.97 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long term Acute Long term Acute
systemic
Acute local
collection; Indoors,
with LEV present.
ventilation [E49].
ES3-W7 Use in contained batch
processes;
With sample
collection; Outdoors
3 Handle substance within a closed system
[E47]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out operation
for more than 1 hour [OC11] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
12.56 n.a. n.a. n.a. 100
ES3-W8 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No
LEV present.
4 Avoid carrying out operation for more than 1
hour [OC11] or: Wear a respirator conforming
to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
14.35 n.a. n.a. n.a. 100
ES3-W9 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors,
with LEV present.
4 Provide extract ventilation to material transfer
points and other openings [E82].Wear
chemically resistant gloves (tested to EN374)
in combination with ‘basic’ employee training
[PPE16].
7.18 n.a. n.a. n.a. 100
ES3-W10 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
4 Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for more
than 1 hour [OC11] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or
better {PPE29]; Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
10.05 n.a. n.a. n.a. 100
ES3-W11 General exposures;
Batch process; Indoors,
5 Avoid carrying out operation for more than 15
minutes [OC10] or: Wear a respirator
17.94 n.a. n.a. n.a. 200
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long term Acute Long term Acute
systemic
Acute local
No LEV present. conforming to EN140 with Type A/P2 filter or
better {PPE29]; Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES3-W12 General exposures;
Batch process; Indoors,
with LEV present.
5 Provide extract ventilation to points where
emissions occur [E54]. Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee training
[PPE16].
17.94 n.a. n.a. n.a. 200
ES3-W13 General exposures;
Batch process;
Outdoors
5 Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for more
than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or
better {PPE29]; Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
12.56 n.a. n.a. n.a. 200
ES3-W14 Drum/batch transfers;
Non-dedicated facility;
Indoors, No LEV
present.
8a Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling [E39].Avoid
carrying out operation for more than 15
minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES3-W15 Drum/batch transfers;
Non-dedicated facility;
Indoors, with LEV
present.
8a Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling
[E39].Provide extract ventilation to material
transfer points and other openings [E82].Wear
17.94 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long term Acute Long term Acute
systemic
Acute local
chemically resistant gloves (tested to EN374)
in combination with ‘basic’ employee training
[PPE16].
ES3-W16 Drum/batch transfers;
Non-dedicated facility;
Outdoors.
8a Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling
[E39].Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for more
than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or
better {PPE29]; Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
12.56 n.a. n.a. n.a. 100
ES3-W17 Drum/batch transfers;
Dedicated facility;
Indoors, No LEV
present.
8b Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling [E39].Avoid
carrying out operation for more than 15
minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES3-W18 Drum/batch transfers;
Dedicated facility;
Indoors, with LEV
present.
8b Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling [E39].
Provide extract ventilation to material transfer
points and other openings [E82].Wear
chemically resistant gloves (tested to EN374)
in combination with ‘basic’ employee training
[PPE16].
5.38 n.a. n.a. n.a. 100
ES3-W19 Drum/batch transfers; 8b Transfer via enclosed lines [E52]; Clear 12.56 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long term Acute Long term Acute
systemic
Acute local
Dedicated facility;
Outdoors.
transfer lines prior to de-coupling [E39].
Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for more
than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or
better {PPE29]; Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES3-W20 Drum and small
package filling;
Indoors, No LEV
present.
9 Use in semi-automated and predominantly
enclosed filling lines [E41]. Avoid carrying
out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to
EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES3-W21 Drum and small
package filling;
Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill points
supplied with local extract ventilation [E51].
Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee
training [PPE16].
17.94 n.a. n.a. n.a. 100
ES3-W22 Drum and small
package filling;
Outdoors.
9 Use in semi-automated and predominantly
enclosed filling lines [E41]. Ensure operation
is undertaken outdoors [E69]. Avoid carrying
out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to
EN140 with Type A/P2 filter or better
{PPE29];
Wear chemically resistant gloves (tested to
12.56 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PROC Risk Management Measures Inhalatory exposure
(mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long term Acute Long term Acute
systemic
Acute local
EN374) in combination with ‘basic’ employee
training [PPE16].
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1.3.2.2. Consumer exposure
Not applicable.
1.3.2.3. Indirect exposure of humans via the environment (oral)
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible as reflected by the values below.
LOCAL ES3-E1
local Concentration in wet fish kg/kgwwt 3.18E-09
local concentration in drinking water kg/m3 1.01E-06
local concentration in meat (wet weight) kg/kgwwt 2.62E-13
local concentration in milk (wet weight) kg/kgwwt 2.62E-12
1.3.2.4. Environmental exposure
Identifier ES3-E1
Manufacture of Intermediates at Production
Sites
The exposure scenario is based A&B tables
IC= 3 and UC= 33
Release fraction to air from process 1.0E-03
Release fraction to wastewater from process 5.0E-04
Release fraction to soil from process (regional
only) 0
Local release to air (kg/d) 6.84
Local release to sewage (kg/d) 3.42
Local release to soil (kg/d) 0
Fraction remaining in water after STP
treatement (Fwater) 3.25E-02
Removal in STP (fraction) 9.5E-01
1.3.2.4.1 Predicted exposure concentrations in aquatic the STP and in the aquatic compartments
(freshwater, seawater and sediments)
Local Concentration, Compartment: STP and aquatic unit ES3-E1
Local PEC in surface water during emission episode
(dissolved) mg/L 1.18E-03
Annual average local PEC in surface water (dissolved) mg/L 1.01E-03
Local PEC in fresh water sediment during emission
episode mg/kg dwt 5.03E-03
Local PEC in sea water during emission episode mg/L 1.22E-04
Annual average local PEC in sea water (dissolved) mg/L 1.04E-04
Local PEC in marine sediment during emission episode mg/kg dwt 5.17E-04
PEC for microorganisms in STP mg/L 1.00E-02
Comments
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1.3.2.4.2 Predicted exposure concentration in soils
Local Concentration, Compartment: soil unit ES3-E1
Local PEC in agricultural soil, averaged over 30 days mg/kg dwt 1.56E-04
Local PEC agricultural soil, averaged over 180 days mg/kg dwt 1.56E-04
Local PEC in grass land, averaged over 180 days mg.kg dwt 3.08E-04
Comments
1.3.2.4.3 Predicted exposure concentration in the atmospheric compartment
Local Concentration,
Compartment: air unit ES3-E1
Annual average local PEC in air
(total) kg/m
3 1.74E-09
Comments
1.3.2.4.4 Predicted exposure concentration in food for secondary poisoning
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible. The table below illustrates the negligible PECs as a function of secondary
poisoning.
Secondary poisoning unit ES3-E1
Conc. in fish for secondary poisoning in freshwater
environment mg/kgwwt 1.88E-03
Conc. in fish for secondary poisoning in marine
environment mg/kgwwt 1.99E-04
Conc. in fish-eating predator for marine toppredators mg/kgwwt 9.52E-05
Conc. in earthworms for secondary poisoning mg/kgwwt 1.90E-02
Comments
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1.4. Exposure scenario 4: Polymerization at downstream user sites
This scenario covers the use of methyl acrylate as an intermediate or monomer in the production of
polymers and resins at downstream user sites (including material receipt, preparation, mixing and
reaction, bulk transfer and storage, as well as equipment cleaning and maintenance. This scenario
covers both wet and dry polymerization processes.
1.4.1. Exposure scenario
Section 1 Exposure Scenario Title
Title Polymerization at downstream user sites
Sector of Use SU8, SU9, SU12
Process Category PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9
Product Category PC19, PC32
Article Category n/a
Environmental release
Category
ERC6C, ERC6D
Specific environmental
release category
n/a
Processes, tasks, activities
covered
Covers the polymerization at downstream user sites for the Process Categories
listed above.
Section 2 Operational conditions and risk management measures
Section 2.1 Control of worker exposure
Product characteristics
Physical form of product Liquid
Volatility Medium volatility
Concentration of
substance in product
Up to 100%
Operational conditions
Amounts used Not relevant for this scenario
Frequency and duration of
use
Covers daily exposures up to 8 hours (unless stated differently) [G2].
Human factors not
influenced by risk
management
None identified for this scenario.
Other Operational
Conditions affecting
worker exposure
Assumes activities are at ambient temperature (unless stated differently) [G17];
Assumes a good basic standard of occupational hygiene is implemented [G1].
Since methyl acrylate is a potential skin sensitizer, the use of chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training is required when handling methyl acrylate and
where indicated under the Risk Management Measures (RMMs) for a given scenario. Butyl rubber
gloves with a minimum thickness of 0.7 mm and a chemical specific breakthrough time of >480
minutes are required for these scenarios.
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Risk Management Measures Detailed information on this Exposure Scenario can be found in
appendix A.
Identifier* Contributing Scenarios Process
Categories
Risk Management Measures
ES4-W1 General exposures (closed
systems); Indoors, No
LEV present.
1 Handle substance within a closed system [E47].
ES4-W2 General exposures (closed
systems); With sample
collection; Indoors, No
LEV present.
2 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES4-W3 General exposures (closed
systems); With sample
collection; Indoors, with
LEV present.
2 Handle substance within a closed system [E47].
Provide extract ventilation to points where emissions
occur [E54].
ES4-W4 General exposures (closed
systems); With sample
collection; Outdoors.
2 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 4 hours [OC12]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES4-W5 Use in contained batch
processes; With sample
collection; Indoors, No
LEV present.
3 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES4-W6 Use in contained batch
processes;
With sample collection;
Indoors, with LEV present.
3 Handle substance within a predominantly closed
system provided with extract ventilation [E49].
ES4-W7 Use in contained batch
processes;
With sample collection;
Outdoors
3 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES4-W8 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No
LEV present.
4 Avoid carrying out operation for more than 1 hour
[OC11] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES4-W9 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with
LEV present.
4 Provide extract ventilation to material transfer points
and other openings [E82].Wear chemically resistant
gloves (tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES4-W10 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
4 Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
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ES4-W11 General exposures; Batch
process; Indoors, No LEV
present.
5 Avoid carrying out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES4-W12 General exposures; Batch
process; Indoors, with
LEV present.
5 Provide extract ventilation to points where emissions
occur [E54]. Wear chemically resistant gloves (tested
to EN374) in combination with ‘basic’ employee
training [PPE16].
ES4-W13 General exposures; Batch
process; Outdoors
5 Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES4-W14 Drum/batch transfers;
Non-dedicated facility;
Indoors, No LEV present.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES4-W15 Drum/batch transfers;
Non-dedicated facility;
Indoors, with LEV present.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES4-W16 Drum/batch transfers;
Non-dedicated facility;
Outdoors.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES4-W17 Drum/batch transfers;
Dedicated facility;
Indoors, No LEV present.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES4-W18 Drum/batch transfers;
Dedicated facility;
Indoors, with LEV present.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
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ES4-W19 Drum/batch transfers;
Dedicated facility;
Outdoors.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES4-W20 Drum and small package
filling; Indoors, No LEV
present.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES4-W21 Drum and small package
filling; Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill points supplied
with local extract ventilation [E51]. Wear chemically
resistant gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES4-W22 Drum and small package
filling; Outdoors.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out operation for more
than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29];
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
Section 2 Operational conditions and risk management measures
Section 2.2 Control of environmental exposure
Identifier*: Polymerization at Downstream
User Sites ES4-E1
Contributing scenario Industrial Use
Environmental Release Category ERC 6C, ERC 6D
Specific ERC -
Assessment scenario IC=11, UC=33
Operational Conditions
Amounts used
Amounts used in the EU (tonnes/year) 7.0E04
Fraction of EU tonnage used in region 1.0
Fraction of main source to local
environment 0.05
Fraction of substance in end-use products 1
Frequency and duration of use
Type of release Continuous
Emission days (days/year) 300
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Section 2 Operational conditions and risk management measures
Environmental factors not influenced by
risk management
Local freshwater dilution factor 10 (default)
Local marine water dilution factor 100 (default)
Other given operational conditions
affecting environmental exposure Not applicable
Risk Management Measures
Conditions and measures related to
municipal sewage treatment plant
E13.20 - Biological treatment – Anaerobic – For soluble
biodegradable contaminants
E13.21 - Biological treatment – Aerobic – For soluble
biodegradable contaminants
E13.23 - Biological treatment - Central Biological Waste
Water Treatment - For soluble biodegradable
contaminants
Estimated substance removal from
wastewater via domestic sewage treatment
(%) 95 %
Conditions and measures related to
external treatment of waste for disposal No application of sludge to soil
Conditions and measures related to
external recovery of waste
Other environmental control measures
additional to above
Dispose of waste cans and containers according to local
regulations.
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
1.4.2. Exposure estimation
1.4.2.1. Workers exposure
The worker exposure estimates for the activities associated with this use of methyl acrylate have been assessed using ECETOC TRA v2, unless stated differently (see appendix B). Assessment parameter default values: Fugacity: moderate Type of Use; industrial Concentration: > 25 % Local Exhaust Ventilation: indoor scenarios assessed both with and without LEV Duration of Exposure: > 4 hours/day unless indicated under RMMs Respiratory Protection Equipment: none required unless indicated under RMMs The ECETOC TRA v2 estimates task based exposure. The exposure estimates shown are representative for activities lasting up to 8 hours. Due to the activity based character of this estimation tool, these exposure estimates are thereby also representative for short term activities (e.g., 15 minutes to 1 hour). Therefore no short term inhalatory exposure estimates are calculated nor shown in the table below (indicated by n.a.), since long term (8 hour) estimates already cover short term exposure.
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Identifier Contributing
scenarios
PROC Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
ES4-W1 General exposures
(closed systems);
Indoors, No LEV
present.
1 Handle substance within a closed system [E47]. 0.04 n.a. n.a. n.a. 100
ES4-W2 General exposures
(closed systems);
With sample
collection; Indoors,
No LEV present.
2 Handle substance within a closed system [E47].
Avoid carrying out operation for more than 1
hour [OC11] or: Wear a respirator conforming
to EN140 with Type A/P2 filter or better
{PPE29]
7.18 n.a. n.a. n.a. 200
ES4-W3 General exposures
(closed systems);
With sample
collection; Indoors,
with LEV present.
2 Handle substance within a closed system [E47].
Provide extract ventilation to points where
emissions occur [E54].
3.59 n.a. n.a. n.a. 200
ES4-W4 General exposures
(closed systems);
With sample
collection; Outdoors.
2 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69].
Avoid carrying out operation for more than 4
hours [OC12] or: Wear a respirator conforming
to EN140 with Type A/P2 filter or better
{PPE29]
15.07 n.a. n.a. n.a. 200
ES4-W5 Use in contained
batch processes; With
sample collection;
Indoors, No LEV
present.
3 Handle substance within a closed system [E47].
Avoid carrying out operation for more than 1
hour [OC11] or: Wear a respirator conforming
to EN140 with Type A/P2 filter or better
{PPE29]
17.94 n.a. n.a. n.a. 100
ES4-W6 Use in contained
batch processes; With
sample collection;
3 Handle substance within a predominantly closed
system provided with extract ventilation [E49].
8.97 n.a. n.a. n.a. 100
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Identifier Contributing
scenarios
PROC Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
Indoors, with LEV
present.
ES4-W7 Use in contained
batch processes; With
sample collection;
Outdoors
3 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69].
Avoid carrying out operation for more than 1
hour [OC11] or: Wear a respirator conforming
to EN140 with Type A/P2 filter or better
{PPE29]
12.56 n.a. n.a. n.a. 100
ES4-W8 Use in contained
batch processes;
Drum/batch transfers;
With sample
collection; Indoors,
No LEV present.
4 Avoid carrying out operation for more than 1
hour [OC11] or: Wear a respirator conforming
to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
14.35 n.a. n.a. n.a. 100
ES4-W9 Use in contained
batch processes;
Drum/batch transfers;
With sample
collection; Indoors,
with LEV present.
4 Provide extract ventilation to material transfer
points and other openings [E82].Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training
[PPE16].
7.18 n.a. n.a. n.a. 100
ES4-W10 Use in contained
batch processes;
Drum/batch transfers;
With sample
collection; Outdoors
4 Ensure operation is undertaken outdoors [E69].
Avoid carrying out operation for more than 1
hour [OC11] or: Wear a respirator conforming
to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
10.05 n.a. n.a. n.a. 100
ES4-W11 General exposures; 5 Avoid carrying out operation for more than 15 17.94 n.a. n.a. n.a. 200
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Identifier Contributing
scenarios
PROC Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
Batch process;
Indoors, No LEV
present.
minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or
better {PPE29]; Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES4-W12 General exposures;
Batch process;
Indoors, with LEV
present.
5 Provide extract ventilation to points where
emissions occur [E54]. Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee training
[PPE16].
17.94 n.a. n.a. n.a. 200
ES4-W13 General exposures;
Batch process;
Outdoors
5 Ensure operation is undertaken outdoors [E69].
Avoid carrying out operation for more than 15
minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or
better {PPE29]; Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
12.56 n.a. n.a. n.a. 200
ES4-W14 Drum/batch transfers;
Non-dedicated
facility; Indoors, No
LEV present.
8a Transfer via enclosed lines [E52]; Clear transfer
lines prior to de-coupling [E39].Avoid carrying
out operation for more than 15 minutes [OC10]
or: Wear a respirator conforming to EN140 with
Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training
[PPE16].
17.94 n.a. n.a. n.a. 100
ES4-W15 Drum/batch transfers;
Non-dedicated
facility; Indoors, with
8a Transfer via enclosed lines [E52]; Clear transfer
lines prior to de-coupling [E39].Provide extract
ventilation to material transfer points and other
17.94 n.a. n.a. n.a. 100
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Identifier Contributing
scenarios
PROC Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
LEV present. openings [E82].Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES4-W16 Drum/batch transfers;
Non-dedicated
facility; Outdoors.
8a Transfer via enclosed lines [E52]; Clear transfer
lines prior to de-coupling [E39].Ensure
operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to
EN140 with Type A/P2 filter or better {PPE29];
Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee
training [PPE16].
12.56 n.a. n.a. n.a. 100
ES4-W17 Drum/batch transfers;
Dedicated facility;
Indoors, No LEV
present.
8b Transfer via enclosed lines [E52]; Clear transfer
lines prior to de-coupling [E39].Avoid carrying
out operation for more than 15 minutes [OC10]
or: Wear a respirator conforming to EN140 with
Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training
[PPE16].
17.94 n.a. n.a. n.a. 100
ES4-W18 Drum/batch transfers;
Dedicated facility;
Indoors, with LEV
present.
8b Transfer via enclosed lines [E52]; Clear transfer
lines prior to de-coupling [E39]. Provide extract
ventilation to material transfer points and other
openings [E82].Wear chemically resistant
gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
5.38 n.a. n.a. n.a. 100
ES4-W19 Drum/batch transfers;
Dedicated facility;
8b Transfer via enclosed lines [E52]; Clear transfer
lines prior to de-coupling [E39]. Ensure
12.56 n.a. n.a. n.a. 100
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Identifier Contributing
scenarios
PROC Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
Outdoors. operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to
EN140 with Type A/P2 filter or better {PPE29];
Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee
training [PPE16].
ES4-W20 Drum and small
package filling;
Indoors, No LEV
present.
9 Use in semi-automated and predominantly
enclosed filling lines [E41]. Avoid carrying out
operation for more than 15 minutes [OC10] or:
Wear a respirator conforming to EN140 with
Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training
[PPE16].
17.94 n.a. n.a. n.a. 100
ES4-W21 Drum and small
package filling;
Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill points
supplied with local extract ventilation [E51].
Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee
training [PPE16].
17.94 n.a. n.a. n.a. 100
ES4-W22 Drum and small
package filling;
Outdoors.
9 Use in semi-automated and predominantly
enclosed filling lines [E41]. Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10] or:
Wear a respirator conforming to EN140 with
Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training
12.56 n.a. n.a. n.a. 100
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Identifier Contributing
scenarios
PROC Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
[PPE16].
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1.4.2.2. Consumer exposure
Not applicable.
1.4.2.3. Indirect exposure of humans via the environment (oral)
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible as reflected by the values below.
LOCAL ES4-E1
local Concentration in wet fish kg/kgwwt 1.23E-09
local concentration in drinking water kg/m3 4.55E-05
local concentration in meat (wet weight) kg/kgwwt 1.87E-11
local concentration in milk (wet weight) kg/kgwwt 1.87E-10
1.4.2.4. Environmental exposure
Identifier ES4-E1
Polymerization at Downstream User
Sites
The exposure scenario is based A&B tables
IC= 11 and UC= 33
Release fraction to air from process 5.00E-02
Release fraction to wastewater from
process 1.00E-02
Release fraction to soil from process
(regional only) 0
Local release to air (kg/d) 583
Local release to sewage (kg/d) 117
Local release to soil (kg/d) 0
Fraction remaining in water after STP
treatement (Fwater) 3.25E-02
Removal in STP (fraction) 9.5E-01
1.4.2.4.1 Predicted exposure concentrations in aquatic the STP and in the aquatic compartments
(freshwater, seawater and sediments)
Local Concentration, Compartment: STP and aquatic unit ES4-E1
Local PEC in surface water during emission episode
(dissolved) mg/L 4.35E-04
Annual average local PEC in surface water (dissolved) mg/L 3.90E-04
Local PEC in fresh water sediment during emission
episode mg/kg dwt 1.84E-03
Local PEC in sea water during emission episode mg/L 1.22E-04
Annual average local PEC in sea water (dissolved) mg/L 1.04E-04
Local PEC in marine sediment during emission episode mg/kg dwt 5.17E-04
PEC for microorganisms in STP mg/L 1.00E-02
Comments
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1.4.2.4.2 Predicted exposure concentration in soils
Local Concentration, Compartment: soil unit ES4-E1
Local PEC in agricultural soil, averaged over 30
days mg/kg dwt 1.19E-02
Local PEC agricultural soil, averaged over 180
days mg/kg dwt 1.19E-02
Local PEC in grass land, averaged over 180 days mg.kg dwt 1.91E-02
Comments
1.4.2.4.3 Predicted exposure concentration in the atmospheric compartment
Local Concentration,
Compartment: air unit ES4-E1
Annual average local PEC in air
(total) kg/m
3 1.33E-07
Comments
1.4.2.4.4 Predicted exposure concentration in food for secondary poisoning
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible. The table below illustrates the negligible PECs as a function of secondary
poisoning.
Secondary poisoning unit ES4-E1
Conc. in fish for secondary poisoning in freshwater
environment mg/kgwwt 9.08E-04
Conc. in fish for secondary poisoning in marine
environment mg/kgwwt 1.99E-04
Conc. in fish-eating predator for marine toppredators mg/kgwwt 9.52E-05
Conc. in earthworms for secondary poisoning mg/kgwwt 1.90E-02
Comments
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1.5. Exposure scenario 5: Manufacture of intermediates at
downstream user sites
This scenario covers the use of methyl acrylate as a chemical intermediate in monomer synthesis
(transesterification or functionalisation) at downstream user sites.
1.5.1. Exposure scenario
Section 1 Exposure Scenario Title
Title Manufacture of intermediates at downstream user sites
Sector of Use SU8, SU9
Process Category PROC1, PROC2, PROC3, PROC4, PROC5, PROC8a, PROC8b, PROC9
Product Category PC19
Article Category n/a
Environmental release
Category
ERC6A
Specific environmental
release category
n/a
Processes, tasks, activities
covered
Covers the manufacture of intermediates at downstream user sites for the Process
Categories listed above.
Section 2 Operational conditions and risk management measures
Section 2.1 Control of worker exposure
Product characteristics
Physical form of product Liquid
Volatility Medium volatility
Concentration of
substance in product
Up to 100%
Operational conditions
Amounts used Not relevant for this scenario
Frequency and duration of
use
Covers daily exposures up to 8 hours (unless stated differently) [G2].
Human factors not
influenced by risk
management
None identified for this scenario.
Other Operational
Conditions affecting
worker exposure
Assumes activities are at ambient temperature (unless stated differently) [G17];
Assumes a good basic standard of occupational hygiene is implemented [G1].
Since methyl acrylate is a potential skin sensitizer, the use of chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training is required when handling methyl acrylate and
where indicated under the Risk Management Measures (RMMs) for a given scenario. Butyl rubber
gloves with a minimum thickness of 0.7 mm and a chemical specific breakthrough time of >480
minutes are required for these scenarios.
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Risk Management Measures Detailed information on this Exposure Scenario can be found in
appendix A.
Identifier* Contributing Scenarios Process
Categories
Risk Management Measures
ES5-W1 General exposures (closed
systems); Indoors, No
LEV present.
1 Handle substance within a closed system [E47].
ES5-W2 General exposures (closed
systems); With sample
collection; Indoors, No
LEV present.
2 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES5-W3 General exposures (closed
systems); With sample
collection; Indoors, with
LEV present.
2 Handle substance within a closed system [E47].
Provide extract ventilation to points where emissions
occur [E54].
ES5-W4 General exposures (closed
systems); With sample
collection; Outdoors.
2 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 4 hours [OC12]
or: Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES5-W5 Use in contained batch
processes; With sample
collection; Indoors, No
LEV present.
3 Handle substance within a closed system [E47]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES5-W6 Use in contained batch
processes;
With sample collection;
Indoors, with LEV present.
3 Handle substance within a predominantly closed
system provided with extract ventilation [E49].
ES5-W7 Use in contained batch
processes;
With sample collection;
Outdoors
3 Handle substance within a closed system [E47].
Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
ES5-W8 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No
LEV present.
4 Avoid carrying out operation for more than 1 hour
[OC11] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES5-W9 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with
LEV present.
4 Provide extract ventilation to material transfer points
and other openings [E82].Wear chemically resistant
gloves (tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES5-W10 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
4 Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
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ES5-W11 General exposures; Batch
process; Indoors, No LEV
present.
5 Avoid carrying out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES5-W12 General exposures; Batch
process; Indoors, with
LEV present.
5 Provide extract ventilation to points where emissions
occur [E54]. Wear chemically resistant gloves (tested
to EN374) in combination with ‘basic’ employee
training [PPE16].
ES5-W13 General exposures; Batch
process; Outdoors
5 Ensure operation is undertaken outdoors [E69]. Avoid
carrying out operation for more than 15 minutes
[OC10] or: Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
ES5-W14 Drum/batch transfers;
Non-dedicated facility;
Indoors, No LEV present.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES5-W15 Drum/batch transfers;
Non-dedicated facility;
Indoors, with LEV present.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES5-W16 Drum/batch transfers;
Non-dedicated facility;
Outdoors.
8a Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES5-W17 Drum/batch transfers;
Dedicated facility;
Indoors, No LEV present.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39].Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES5-W18 Drum/batch transfers;
Dedicated facility;
Indoors, with LEV present.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Provide extract ventilation
to material transfer points and other openings
[E82].Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
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ES5-W19 Drum/batch transfers;
Dedicated facility;
Outdoors.
8b Transfer via enclosed lines [E52]; Clear transfer lines
prior to de-coupling [E39]. Ensure operation is
undertaken outdoors [E69]. Avoid carrying out
operation for more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type A/P2 filter
or better {PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with ‘basic’
employee training [PPE16].
ES5-W20 Drum and small package
filling; Indoors, No LEV
present.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves (tested to
EN374) in combination with ‘basic’ employee training
[PPE16].
ES5-W21 Drum and small package
filling; Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill points supplied
with local extract ventilation [E51]. Wear chemically
resistant gloves (tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES5-W22 Drum and small package
filling; Outdoors.
9 Use in semi-automated and predominantly enclosed
filling lines [E41]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out operation for more
than 15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2 filter or better
{PPE29];
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16].
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and
2and appendices) related to this contributing scenario of the ES
Section 2 Operational conditions and risk management measures
Section 2.2 Control of environmental exposure
Identifier*: Manufacture of Intermediates
at Downstream User Sites. ES5-E1
Contributing scenario Industrial Use
Environmental Release Category ERC 6A
Specific ERC -
Assessment scenario IC=11, UC=33
Operational Conditions
Amounts used
Amounts used in the EU (tonnes/year) 2.33E04
Fraction of EU tonnage used in region 1.0
Fraction of main source to local
environment 0.25
Fraction of substance in end-use products 1
Frequency and duration of use
Type of release Continuous
Emission days (days/year) 300
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Section 2 Operational conditions and risk management measures
Environmental factors not influenced by
risk management
Local freshwater dilution factor 10 (default)
Local marine water dilution factor 100 (default)
Other given operational conditions
affecting environmental exposure Not applicable
Risk Management Measures
Conditions and measures related to
municipal sewage treatment plant
E13.20 - Biological treatment – Anaerobic – For soluble
biodegradable contaminants
E13.21 - Biological treatment – Aerobic – For soluble
biodegradable contaminants
E13.23 - Biological treatment - Central Biological Waste
Water Treatment - For soluble biodegradable
contaminants
Estimated substance removal from
wastewater via domestic sewage treatment
(%) 95 %
Conditions and measures related to
external treatment of waste for disposal No application of sludge to soil
Conditions and measures related to
external recovery of waste
Other environmental control measures
additional to above
Dispose of waste cans and containers according to local
regulations.
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
1.5.2. Exposure estimation
1.5.2.1. Workers exposure
The worker exposure estimates for the activities associated with this use of methyl acrylate have been assessed using ECETOC TRA v2, unless stated differently (see appendix B). Assessment parameter default values: Fugacity: moderate Type of Use; industrial Concentration: > 25 % Local Exhaust Ventilation: indoor scenarios assessed both with and without LEV Duration of Exposure: > 4 hours/day unless indicated under RMMs Respiratory Protection Equipment: none required unless indicated under RMMs The ECETOC TRA v2 estimates task based exposure. The exposure estimates shown are representative for activities lasting up to 8 hours. Due to the activity based character of this estimation tool, these exposure estimates are thereby also representative for short term activities (e.g., 15 minutes to 1 hour). Therefore no short term inhalatory exposure estimates are calculated nor shown in the table below (indicated by n.a.), since long term (8 hour) estimates already cover short term exposure.
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Identifier Contributing scenarios PRO
C
Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
ES5-W1 General exposures (closed
systems); Indoors, No
LEV present.
1 Handle substance within a closed system
[E47].
0.04 n.a. n.a. n.a. 100
ES5-W2 General exposures (closed
systems); With sample
collection; Indoors, No
LEV present.
2 Handle substance within a closed system
[E47]. Avoid carrying out operation for
more than 1 hour [OC11] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
7.18 n.a. n.a. n.a. 200
ES5-W3 General exposures (closed
systems); With sample
collection; Indoors, with
LEV present.
2 Handle substance within a closed system
[E47]. Provide extract ventilation to points
where emissions occur [E54].
3.59 n.a. n.a. n.a. 200
ES5-W4 General exposures (closed
systems); With sample
collection; Outdoors.
2 Handle substance within a closed system
[E47]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 4 hours [OC12] or:
Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]
15.07 n.a. n.a. n.a. 200
ES5-W5 Use in contained batch
processes; With sample
collection; Indoors, No
LEV present.
3 Handle substance within a closed system
[E47]. Avoid carrying out operation for
more than 1 hour [OC11] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]
17.94 n.a. n.a. n.a. 100
ES5-W6 Use in contained batch
processes; With sample
collection; Indoors, with
LEV present.
3 Handle substance within a predominantly
closed system provided with extract
ventilation [E49].
8.97 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PRO
C
Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
ES5-W7 Use in contained batch
processes; With sample
collection; Outdoors
3 Handle substance within a closed system
[E47]. Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 1 hour [OC11] or:
Wear a respirator conforming to EN140
with Type A/P2 filter or better {PPE29]
12.56 n.a. n.a. n.a. 100
ES5-W8 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No
LEV present.
4 Avoid carrying out operation for more than
1 hour [OC11] or: Wear a respirator
conforming to EN140 with Type A/P2
filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
14.35 n.a. n.a. n.a. 100
ES5-W9 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with
LEV present.
4 Provide extract ventilation to material
transfer points and other openings
[E82].Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
7.18 n.a. n.a. n.a. 100
ES5-W10 Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
4 Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for
more than 1 hour [OC11] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
10.05 n.a. n.a. n.a. 100
ES5-W11 General exposures; Batch
process; Indoors, No LEV
5 Avoid carrying out operation for more than
15 minutes [OC10] or: Wear a respirator
17.94 n.a. n.a. n.a. 200
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Identifier Contributing scenarios PRO
C
Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
present. conforming to EN140 with Type A/P2
filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
ES5-W12 General exposures; Batch
process; Indoors, with
LEV present.
5 Provide extract ventilation to points where
emissions occur [E54]. Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
17.94 n.a. n.a. n.a. 200
ES5-W13 General exposures; Batch
process; Outdoors
5 Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
12.56 n.a. n.a. n.a. 200
ES5-W14 Drum/batch transfers;
Non-dedicated facility;
Indoors, No LEV present.
8a Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling
[E39].Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES5-W15 Drum/batch transfers; 8a Transfer via enclosed lines [E52]; Clear 17.94 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PRO
C
Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
Non-dedicated facility;
Indoors, with LEV
present.
transfer lines prior to de-coupling
[E39].Provide extract ventilation to
material transfer points and other openings
[E82].Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES5-W16 Drum/batch transfers;
Non-dedicated facility;
Outdoors.
8a Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling
[E39].Ensure operation is undertaken
outdoors [E69]. Avoid carrying out
operation for more than 15 minutes
[OC10] or: Wear a respirator conforming
to EN140 with Type A/P2 filter or better
{PPE29]; Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
12.56 n.a. n.a. n.a. 100
ES5-W17 Drum/batch transfers;
Dedicated facility;
Indoors, No LEV present.
8b Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling [E39].
Avoid carrying out operation for more than
15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2
filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
17.94 n.a. n.a. n.a. 100
ES5-W18 Drum/batch transfers;
Dedicated facility;
Indoors, with LEV
8b Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling [E39].
Provide extract ventilation to material
transfer points and other openings
5.38 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PRO
C
Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
present. [E82].Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
ES5-W19 Drum/batch transfers;
Dedicated facility;
Outdoors.
8b Transfer via enclosed lines [E52]; Clear
transfer lines prior to de-coupling [E39].
Ensure operation is undertaken outdoors
[E69]. Avoid carrying out operation for
more than 15 minutes [OC10] or: Wear a
respirator conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
12.56 n.a. n.a. n.a. 100
ES5-W20 Drum and small package
filling; Indoors, No LEV
present.
9 Use in semi-automated and predominantly
enclosed filling lines [E41]. Avoid
carrying out operation for more than 15
minutes [OC10] or: Wear a respirator
conforming to EN140 with Type A/P2
filter or better {PPE29]; Wear chemically
resistant gloves (tested to EN374) in
combination with ‘basic’ employee
training [PPE16].
17.94 n.a. n.a. n.a. 100
ES5-W21 Drum and small package
filling; Indoors, with LEV
present.
9 Fill containers/cans at dedicated fill points
supplied with local extract ventilation
[E51]. Wear chemically resistant gloves
(tested to EN374) in combination with
‘basic’ employee training [PPE16].
17.94 n.a. n.a. n.a. 100
ES5-W22 Drum and small package 9 Use in semi-automated and predominantly 12.56 n.a. n.a. n.a. 100
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Identifier Contributing scenarios PRO
C
Risk Management Measures Inhalatory
exposure (mg/m3)
Dermal exposure
(mg/kg/day)
Dermal
exposure
(µg/cm2)
Long
term
Acute Long
term
Acute
systemic
Acute
local
filling; Outdoors. enclosed filling lines [E41]. Ensure
operation is undertaken outdoors [E69].
Avoid carrying out operation for more than
15 minutes [OC10] or: Wear a respirator
conforming to EN140 with Type
A/P2 filter or better {PPE29]; Wear
chemically resistant gloves (tested to
EN374) in combination with ‘basic’
employee training [PPE16].
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1.5.2.2. Consumer exposure
Not applicable.
1.5.2.3. Indirect exposure of humans via the environment (oral)
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible as reflected by the values below.
LOCAL ES5-E1
local Concentration in wet fish kg/kgwwt 3.18E-09
local concentration in drinking water kg/m3 1.58E-06
local concentration in meat (wet weight) kg/kgwwt 6.49E-13
local concentration in milk (wet weight) kg/kgwwt 6.49E-12
1.5.2.4. Environmental exposure
Identifier ES5-E1
Manufacture of Intermediates at
Downstream User Sites
The exposure scenario is based A&B
tables
IC= 3 and UC= 33
Release fraction to air from process 1.0E-03
Release fraction to wastewater from
process 5.0E-04
Release fraction to soil from process
(regional only) 0
Local release to air (kg/d) 19.4
Local release to sewage (kg/d) 9.72
Local release to soil (kg/d) 0
Fraction remaining in water after STP
treatement (Fwater) 3.25E-02
Removal in STP (fraction) 9.5E-01
1.5.2.4.1 Predicted exposure concentrations in aquatic the STP and in the aquatic compartments
(freshwater, seawater and sediments)
Local Concentration, Compartment: STP and
aquatic unit ES5-E1
Local PEC in surface water during emission episode
(dissolved) mg/L 1.18E-03
Annual average local PEC in surface water
(dissolved) mg/L 1.01E-03
Local PEC in fresh water sediment during emission
episode mg/kg dwt 5.03E-03
Local PEC in sea water during emission episode mg/L 1.22E-04
Annual average local PEC in sea water (dissolved) mg/L 1.04E-04
Local PEC in marine sediment during emission
episode mg/kg dwt 5.17E-04
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PEC for microorganisms in STP mg/L 1.00E-02
1.5.2.4.2 Predicted exposure concentration in soils
Local Concentration, Compartment: soil unit ES5-E1
Local PEC in agricultural soil, averaged over 30 days mg/kg dwt 4.14E-04
Local PEC agricultural soil, averaged over 180 days mg/kg dwt 4.14E-04
Local PEC in grass land, averaged over 180 days mg.kg dwt 8.48E-04
Comments
1.5.2.4.3 Predicted exposure concentration in the atmospheric compartment
Local Concentration, Compartment:
air unit ES5-E1
Annual average local PEC in air (total) kg/m3 4.62E-09
Comments
1.5.2.4.4 Predicted exposure concentration in food for secondary poisoning
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible. The table below illustrates the negligible PECs as a function of secondary
poisoning.
Secondary poisoning unit ES5-E1
Conc. in fish for secondary poisoning in freshwater
environment mg/kgwwt 1.88E-03
Conc. in fish for secondary poisoning in marine
environment mg/kgwwt 1.99E-04
Conc. in fish-eating predator for marine toppredators mg/kgwwt 9.52E-05
Conc. in earthworms for secondary poisoning mg/kgwwt 6.86E-04
Comments
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1.6. Exposure scenario 6: Use as laboratory reagent
This scenario covers the use and handling of methyl acrylate in small-scale analytical laboratories
associated with production sites and in small research and development facilities.
1.6.1. Exposure scenario
Section 1 Exposure Scenario Title
Title Use as laboratory reagent
Sector of Use SU8, SU9, SU24
Process Category PROC15
Product Category PC19, PC21
Article Category n/a
Environmental release
Category
ERC1
Specific environmental
release category
n/a
Processes, tasks, activities
covered
Covers the use as a laboratory reagent for the Process Category listed above.
Section 2 Operational conditions and risk management measures
Section 2.1 Control of worker exposure
Product characteristics
Physical form of product Liquid
Volatility Medium volatility
Concentration of
substance in product
Up to 100%
Operational conditions
Amounts used Not relevant for this scenario
Frequency and duration of
use
Covers daily exposures up to 8 hours (unless stated differently) [G2].
Human factors not
influenced by risk
management
None identified for this scenario.
Other Operational
Conditions affecting
worker exposure
Assumes activities are at ambient temperature (unless stated differently) [G17];
Assumes a good basic standard of occupational hygiene is implemented [G1].
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Risk Management Measures Detailed information on this Exposure Scenario can be found in
appendix A.
Identifier* Contributing Scenarios Process
Categories
Risk Management Measures
ES6-W1 Laboratory activities;
Indoors, with LEV present.
15 Handle in a fume cupboard or under extract ventilation
[E83].
*Identifier: each contributing scenario of the ES has been assigned a unique identifier which
facilitates tracking all the information (exposure estimation, risk characterization in chapter 1 and 2
and appendices) related to this contributing scenario of the ES
The residues following use in small scale analytical laboratories are incinerated together with residues
from manufacturing at production sites. Thus, this use (PROC15) is linked with ERC1 (manufacture
and distribution) and therefore no further environmental assessment is required.
1.6.2. Exposure estimation
1.6.2.1. Workers exposure
The worker exposure estimates for the activities associated with this use of methyl acrylate have been assessed using ECETOC TRA v2, unless stated differently (see appendix B). Assessment parameter default values: Fugacity: moderate Type of Use; industrial Concentration: > 25 % Local Exhaust Ventilation: with LEV Duration of Exposure: > 4 hours/day Respiratory Protection Equipment: none The ECETOC TRA v2 estimates task based exposure. The exposure estimates shown are representative for activities lasting up to 8 hours. Due to the activity based character of this estimation tool, these exposure estimates are thereby also representative for short term activities (e.g., 15 minutes to 1 hour). Therefore no short term inhalatory exposure estimates are calculated nor shown in the table below (indicated by n.a.), since long term (8 hour) estimates already cover short term exposure.
Identifier Contributing
scenarios
PRO
C
Risk Management
Measures
Inhalatory
exposure
(mg/m3)
Dermal
exposure
(mg/kg/day)
Dermal
exposur
e
(µg/cm2
)
Long
term
Acut
e
Long
term
Acute
systemic
Acute
local
ES6-W1 Laboratory
activities; Indoors,
with LEV present.
15 Handle in a fume
cupboard or under
extract ventilation
[E83].
3.59 n.a. n.a. n.a. 100
1.6.2.2. Consumer exposure
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Not applicable.
1.6.2.3. Indirect exposure of humans via the environment (oral)
The residues following use in small scale analytical laboratories are incinerated together with residues
from manufacturing at production sites. Thus, this use (PROC15) is linked with ERC1 (manufacture
and distribution) and therefore no further environmental assessment is required.
1.6.2.4. Environmental exposure
The residues following use in small scale analytical laboratories are incinerated together with residues
from manufacturing at production sites. Thus, this use (PROC15) is linked with ERC1 (manufacture
and distribution) and therefore no further environmental assessment is required.
1.7. Regional exposure concentrations
Regional concentrations unit value
Regional PEC in surface water (total) mg/L 1.85E-04
Regional PEC in sea water (total) mg/L 2.19E-05
Regional PEC in air (total) kg/m3 1.78E-10
Regional PEC in agricultural soil (total) mg/kg dwt 1.55E-05
Regional PEC in natural soil (total) mg/kg dwt 1.56E-05
Regional PEC in industrial soil (total) mg/kg dwt 1.56E-05
Regional PEC in sediment (total) mg/kg dwt 6.77E-04
Regional PEC in sea water sediment (total) mg/kg dwt 8.13E-05
Comments
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2. RISK CHARACTERISATION
The risk characterisation of substance methyl acrylate has been conducted based on the PNECs and
DNELs in the following tables.
Table 2.1 PNECs
Compartments PNEC
STP 10.0 mg L-1
Freshwater 2.72E-03 mg L-1
Freshwater sediment 1.15E-02 mg kgdwt-1
Marine water 2.72E-04 mg L-1
Marine water
sediment 1.15E-03 mg kgdwt-1
Soil 1.13 mg kgdwt-1
Table 2.2 DN(M)ELs for workers
Acute –
systemic effects
Acute –
local effects
Long-term –
systemic effects
Long-term –
local effects
dermal (mg/kg
bw /day)
Inhalation
(mg/m3)
Dermal
(µg/cm2)
Inhalation
(mg/m3)
Dermal
(mg/kg bw
/day)
Inhalation
(mg/m3)
Dermal
(µg/cm2)
Inhalation
(mg/m3)
n.a. n.a. 490 n.a. n.a. n.a. n.a. 18
n.a. = not applicable
Table 2.3 DN(M)ELs for General Population
Acute –
systemic effects
Acute –
local effects
Long-term –
systemic effects
Long-term – local
effects
Dermal
(mg/kg
bw /day)
Inhalation
(mg/m3/day)
Oral
(mg/kg
bw/day)
Dermal
(µg/cm2)
Inhalatio
n
(mg/m3)
Dermal
(mg/kg
bw /day)
Inhalation
(mg/kg
bw/day)
Oral
(mg/kg
bw /day)
Dermal
(µg/cm2)
Inhalatio
n
(mg/m3)
n.a. n.a. n.a. n.a. n.a. n.a. n.a. n.a. n.a. n.a.
n.a. = not applicable
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2.1. Exposure scenario 1: Manufacture and distribution
2.1.1. Human health
2.1.1.1. Workers
Identifier Contributing scenarios Risk Characterization Ratio
Long term (local effects)
Risk Characterization Ratio
Acute (local effects)
Inhalation Dermal Combined
routes
Inhalation Dermal Combined
routes
ES1-W1 General exposures (closed
systems); Indoors, No LEV
present.
0.0020 n.a. n.a. n.a. 0.2041 n.a.
ES1-W2
General exposures (closed
systems); With sample
collection; Indoors, No LEV
present.
0.3986 n.a. n.a. n.a. 0.4082 n.a.
ES1-W3
General exposures (closed
systems); With sample
collection; Indoors, with LEV
present.
0.1993 n.a. n.a. n.a. 0.4082 n.a.
ES1-W4 General exposures (closed
systems); With sample
collection; Outdoors.
0.8371 n.a. n.a. n.a. 0.4082 n.a.
ES1-W5
Use in contained batch
processes; With sample
collection; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES1-W6
Use in contained batch
processes; With sample
collection; Indoors, with LEV
present.
0.4983 n.a. n.a. n.a. 0.2041 n.a.
ES1-W7 Use in contained batch
processes; With sample
collection; Outdoors
0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES1-W8
Drum/batch transfers; Non-
dedicated facility; Indoors,
No LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES1-W9 Drum/batch transfers; Non-
dedicated facility; Indoors,
with LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES1-W10 Drum/batch transfers; Non-
dedicated facility; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES1-W11 Drum/batch transfers;
Dedicated facility; Indoors,
No LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES1-W12 Drum/batch transfers;
Dedicated facility; Indoors, 0.2990 n.a. n.a. n.a. 0.2041 n.a.
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with LEV present.
ES1-W13 Drum/batch transfers;
Dedicated facility; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES1-W14 Drum and small package
filling; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES1-W15 Drum and small package
filling; Indoors, with LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES1-W16 Drum and small package
filling; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
2.1.1.2. Consumers
Not applicable.
2.1.1.3. Indirect exposure of humans via the environment
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible.
2.1.2. Environment
Compartments: Risk Characterization
Ratio
ES1-E1: Manufacture
Site 1
STP 1.00E-03
Freshwater 4.34E-01
Freshwater sediment 4.37E-01
Soil 1.88E-02
Marine water 4.49E-01
Marine water sediment 4.50E-01
Compartments: Risk Characterization Ratio
ES1-E2: Manufacture
Site 2
STP 1.00E-03
Freshwater 4.34E-01
Freshwater sediment 4.37E-01
Soil 1.88E-02
Marine water 4.49E-01
Marine water sediment 4.50E-01
Compartments: Risk Characterization Ratio
ES1-E3: Manufacture
Site 3
STP 1.00E-03
Freshwater 1.60E-01
Freshwater sediment 1.60E-01
Soil 2.21E-03
Marine water 4.49E-01
Marine water sediment 4.50E-01
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2.2. Exposure scenario 2: Polymerization at production sites
2.2.1. Human health
2.2.1.1. Workers
Identifier Contributing scenarios Risk Characterization Ratio
Long term (local effects)
Risk Characterization Ratio
Acute (local effects)
Inhalation Dermal Combined
routes
Inhalation Dermal Combined
routes
ES2-W1
General exposures (closed
systems); Indoors, No LEV
present.
0.0020 n.a. n.a. n.a. 0.2041 n.a.
ES2-W2
General exposures (closed
systems); With sample
collection; Indoors, No LEV
present.
0.3986 n.a. n.a. n.a. 0.4082 n.a.
ES2-W3
General exposures (closed
systems); With sample
collection; Indoors, with LEV
present.
0.1993 n.a. n.a. n.a. 0.4082 n.a.
ES2-W4
General exposures (closed
systems); With sample
collection; Outdoors.
0.8371 n.a. n.a. n.a. 0.4082 n.a.
ES2-W5
Use in contained batch
processes; With sample
collection; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES2-W6
Use in contained batch
processes; With sample
collection; Indoors, with LEV
present.
0.4983 n.a. n.a. n.a. 0.2041 n.a.
ES2-W7
Use in contained batch
processes; With sample
collection; Outdoors
0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES2-W8
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No LEV
present.
0.7972 n.a. n.a. n.a. 0.2041 n.a.
ES2-W9
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with LEV
present.
0.3986 n.a. n.a. n.a. 0.2041 n.a.
ES2-W10
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
0.5581 n.a. n.a. n.a. 0.2041 n.a.
VERSION: 1.2
DATE CREATED: 16/11/2018
Страница 112 из 120
ES2-W11
General exposures; Batch
process; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.4082 n.a.
ES2-W12 General exposures; Batch
process; Indoors, with LEV
present.
0.9965 n.a. n.a. n.a. 0.4082 n.a.
ES2-W13 General exposures; Batch
process; Outdoors 0.6976 n.a. n.a. n.a. 0.4082 n.a.
ES2-W14 Drum/batch transfers; Non-
dedicated facility; Indoors, No
LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES2-W15 Drum/batch transfers; Non-
dedicated facility; Indoors,
with LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES2-W16 Drum/batch transfers; Non-
dedicated facility; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES2-W17 Drum/batch transfers;
Dedicated facility; Indoors,
No LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES2-W18
Drum/batch transfers;
Dedicated facility; Indoors,
with LEV present.
0.2990 n.a. n.a. n.a. 0.2041 n.a.
ES2-W19 Drum/batch transfers;
Dedicated facility; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES2-W20
Drum and small package
filling; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES2-W21
Drum and small package
filling; Indoors, with LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES2-W22 Drum and small package
filling; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
2.2.1.2. Consumers
Not applicable.
2.2.1.3. Indirect exposure of humans via the environment
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible.
2.2.2. Environment
Compartments: Risk Characterization Ratio ES2-E1: Polymerization [Wet] at Production Sites
STP 1.00E-03
Freshwater 4.34E-01
Freshwater sediment 4.37E-01
Soil 2.62E-04
Marine water 4.49E-01
VERSION: 1.2
DATE CREATED: 16/11/2018
Страница 113 из 120
Marine water sediment 4.50E-01
2.3. Exposure scenario 3: Manufacture of intermediates at production
sites
2.3.1. Human health
2.3.1.1. Workers
Identifier Contributing scenarios Risk Characterization Ratio
Long term (local effects)
Risk Characterization Ratio
Acute (local effects)
Inhalati
on
Dermal Combined
routes
Inhalation Dermal Combined
routes
ES3-W1
General exposures (closed
systems); Indoors, No LEV
present.
0.0020 n.a. n.a. n.a. 0.2041 n.a.
ES3-W2
General exposures (closed
systems); With sample
collection; Indoors, No
LEV present.
0.3986 n.a. n.a. n.a. 0.4082 n.a.
ES3-W3
General exposures (closed
systems); With sample
collection; Indoors, with
LEV present.
0.1993 n.a. n.a. n.a. 0.4082 n.a.
ES3-W4
General exposures (closed
systems); With sample
collection; Outdoors.
0.8371 n.a. n.a. n.a. 0.4082 n.a.
ES3-W5
Use in contained batch
processes; With sample
collection; Indoors, No
LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES3-W6
Use in contained batch
processes; With sample
collection; Indoors, with
LEV present.
0.4983 n.a. n.a. n.a. 0.2041 n.a.
ES3-W7
Use in contained batch
processes; With sample
collection; Outdoors
0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES3-W8
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No
LEV present.
0.7972 n.a. n.a. n.a. 0.2041 n.a.
ES3-W9
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with
LEV present.
0.3986 n.a. n.a. n.a. 0.2041 n.a.
ES3-W10
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
0.5581 n.a. n.a. n.a. 0.2041 n.a.
VERSION: 1.2
DATE CREATED: 16/11/2018
Страница 114 из 120
ES3-W11
General exposures; Batch
process; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.4082 n.a.
ES3-W12 General exposures; Batch
process; Indoors, with LEV
present.
0.9965 n.a. n.a. n.a. 0.4082 n.a.
ES3-W13 General exposures; Batch
process; Outdoors 0.6976 n.a. n.a. n.a. 0.4082 n.a.
ES3-W14 Drum/batch transfers; Non-
dedicated facility; Indoors,
No LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES3-W15 Drum/batch transfers; Non-
dedicated facility; Indoors,
with LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES3-W16 Drum/batch transfers; Non-
dedicated facility; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES3-W17 Drum/batch transfers;
Dedicated facility; Indoors,
No LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES3-W18
Drum/batch transfers;
Dedicated facility; Indoors,
with LEV present.
0.2990 n.a. n.a. n.a. 0.2041 n.a.
ES3-W19 Drum/batch transfers;
Dedicated facility; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES3-W20
Drum and small package
filling; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES3-W21
Drum and small package
filling; Indoors, with LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES3-W22 Drum and small package
filling; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
2.3.1.2. Consumers
Not applicable.
2.3.1.3. Indirect exposure of humans via the environment
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible.
2.3.2. Environment
Compartments: Risk Characterization
Ratio
ES3-E1: Manufacture of Intermediates at Production
Sites
STP 1.00E-03
Freshwater 4.34E-01
Freshwater sediment 4.37E-01
VERSION: 1.2
DATE CREATED: 16/11/2018
Страница 115 из 120
Soil 1.38E-04
Marine water 4.49E-01
Marine water sediment 4.50E-01
2.4. Exposure scenario 4: Polymerization at downstream user sites
2.4.1. Human health
2.4.1.1. Workers
Identifier Contributing scenarios Risk Characterization Ratio
Long term (local effects)
Risk Characterization Ratio
Acute (local effects)
Inhalation Dermal Combined
routes
Inhalation Dermal Combined
routes
ES4-W1
General exposures (closed
systems); Indoors, No
LEV present.
0.0020 n.a. n.a. n.a. 0.2041 n.a.
ES4-W2
General exposures (closed
systems); With sample
collection; Indoors, No
LEV present.
0.3986 n.a. n.a. n.a. 0.4082 n.a.
ES4-W3
General exposures (closed
systems); With sample
collection; Indoors, with
LEV present.
0.1993 n.a. n.a. n.a. 0.4082 n.a.
ES4-W4
General exposures (closed
systems); With sample
collection; Outdoors.
0.8371 n.a. n.a. n.a. 0.4082 n.a.
ES4-W5
Use in contained batch
processes; With sample
collection; Indoors, No
LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES4-W6
Use in contained batch
processes; With sample
collection; Indoors, with
LEV present.
0.4983 n.a. n.a. n.a. 0.2041 n.a.
ES4-W7
Use in contained batch
processes; With sample
collection; Outdoors
0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES4-W8
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No
LEV present.
0.7972 n.a. n.a. n.a. 0.2041 n.a.
ES4-W9
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with
LEV present.
0.3986 n.a. n.a. n.a. 0.2041 n.a.
ES4-W10 Use in contained batch
processes; Drum/batch 0.5581 n.a. n.a. n.a. 0.2041 n.a.
VERSION: 1.2
DATE CREATED: 16/11/2018
Страница 116 из 120
transfers; With sample
collection; Outdoors
ES4-W11
General exposures; Batch
process; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.4082 n.a.
ES4-W12
General exposures; Batch
process; Indoors, with
LEV present.
0.9965 n.a. n.a. n.a. 0.4082 n.a.
ES4-W13 General exposures; Batch
process; Outdoors 0.6976 n.a. n.a. n.a. 0.4082 n.a.
ES4-W14
Drum/batch transfers;
Non-dedicated facility;
Indoors, No LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES4-W15
Drum/batch transfers;
Non-dedicated facility;
Indoors, with LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES4-W16
Drum/batch transfers;
Non-dedicated facility;
Outdoors.
0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES4-W17
Drum/batch transfers;
Dedicated facility; Indoors,
No LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES4-W18
Drum/batch transfers;
Dedicated facility; Indoors,
with LEV present.
0.2990 n.a. n.a. n.a. 0.2041 n.a.
ES4-W19
Drum/batch transfers;
Dedicated facility;
Outdoors.
0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES4-W20
Drum and small package
filling; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES4-W21
Drum and small package
filling; Indoors, with LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES4-W22 Drum and small package
filling; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
2.4.1.2. Consumers
Not applicable.
2.4.1.3. Indirect exposure of humans via the environment
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible.
2.4.2. Environment
Compartments: Risk Characterization Ratio ES4-E1: Polymerization at Downstream User Sites
STP 1.00E-03
Freshwater 1.60E-01
Freshwater sediment 1.60E-01
Soil 1.05E-02
VERSION: 1.2
DATE CREATED: 16/11/2018
Страница 117 из 120
Marine water 4.49E-01
Marine water sediment 4.50E-01
2.5. Exposure scenario 5: Manufacture of intermediates at
downstream user sites
2.5.1. Human health
2.5.1.1. Workers
Identifier Contributing scenarios Risk Characterization Ratio
Long term (local effects)
Risk Characterization Ratio
Acute (local effects)
Inhalation Dermal Combined
routes
Inhalation Dermal Combined
routes
ES5-W1
General exposures (closed
systems); Indoors, No LEV
present.
0.0020 n.a. n.a. n.a. 0.2041 n.a.
ES5-W2
General exposures (closed
systems); With sample
collection; Indoors, No LEV
present.
0.3986 n.a. n.a. n.a. 0.4082 n.a.
ES5-W3
General exposures (closed
systems); With sample
collection; Indoors, with LEV
present.
0.1993 n.a. n.a. n.a. 0.4082 n.a.
ES5-W4
General exposures (closed
systems); With sample
collection; Outdoors.
0.8371 n.a. n.a. n.a. 0.4082 n.a.
ES5-W5
Use in contained batch
processes; With sample
collection; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES5-W6
Use in contained batch
processes; With sample
collection; Indoors, with LEV
present.
0.4983 n.a. n.a. n.a. 0.2041 n.a.
ES5-W7
Use in contained batch
processes; With sample
collection; Outdoors
0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES5-W8
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, No LEV
present.
0.7972 n.a. n.a. n.a. 0.2041 n.a.
ES5-W9
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Indoors, with LEV
present.
0.3986 n.a. n.a. n.a. 0.2041 n.a.
VERSION: 1.2
DATE CREATED: 16/11/2018
Страница 118 из 120
ES5-W10
Use in contained batch
processes; Drum/batch
transfers; With sample
collection; Outdoors
0.5581 n.a. n.a. n.a. 0.2041 n.a.
ES5-W11
General exposures; Batch
process; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.4082 n.a.
ES5-W12
General exposures; Batch
process; Indoors, with LEV
present.
0.9965 n.a. n.a. n.a. 0.4082 n.a.
ES5-W13 General exposures; Batch
process; Outdoors 0.6976 n.a. n.a. n.a. 0.4082 n.a.
ES5-W14
Drum/batch transfers; Non-
dedicated facility; Indoors,
No LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES5-W15
Drum/batch transfers; Non-
dedicated facility; Indoors,
with LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES5-W16 Drum/batch transfers; Non-
dedicated facility; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES5-W17
Drum/batch transfers;
Dedicated facility; Indoors,
No LEV present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES5-W18
Drum/batch transfers;
Dedicated facility; Indoors,
with LEV present.
0.2990 n.a. n.a. n.a. 0.2041 n.a.
ES5-W19 Drum/batch transfers;
Dedicated facility; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
ES5-W20
Drum and small package
filling; Indoors, No LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES5-W21
Drum and small package
filling; Indoors, with LEV
present.
0.9965 n.a. n.a. n.a. 0.2041 n.a.
ES5-W22 Drum and small package
filling; Outdoors. 0.6976 n.a. n.a. n.a. 0.2041 n.a.
2.5.1.2. Consumers
Not applicable.
2.5.1.3. Indirect exposure of humans via the environment
The bioaccumulation potential of this substance is very low, therefore secondary poisoning can be
considered negligible.
2.5.2. Environment
Compartments: Risk
Characterization Ratio
ES5-E1: Manufacture of Intermediates at Downstream User
Sites
STP 1.00E-03
Freshwater 4.34E-01
VERSION: 1.2
DATE CREATED: 16/11/2018
Страница 119 из 120
Freshwater sediment 4.37E-01
Soil 3.66E-04
Marine water 4.49E-01
Marine water sediment 4.50E-01
2.6. Exposure scenario 6: Use as laboratory reagent
2.6.1. Human health
2.6.1.1. Workers
Identifier Contributing scenarios Risk Characterization Ratio
Long term (local effects)
Risk Characterization Ratio
Acute (local effects)
Inhalation Dermal Combined
routes
Inhalation Dermal Combined
routes
ES6-W1 Laboratory activities; Indoors,
with LEV present. 0.1993 n.a. n.a. n.a. 0.2041 n.a.
2.6.1.2. Consumers
Not applicable.
2.6.1.3. Indirect exposure of humans via the environment
The residues following use in small scale analytical laboratories are incinerated together with residues from
manufacturing at production sites. Thus, this use (PROC15) is linked with ERC1 (manufacture and
distribution) and therefore no further environmental assessment is required.
2.6.2. Environment
The residues following use in small scale analytical laboratories are incinerated together with residues from
manufacturing at production sites. Thus, this use (PROC15) is linked with ERC1 (manufacture and
distribution) and therefore no further environmental assessment is required.
VERSION: 1.2
DATE CREATED: 16/11/2018
Страница 120 из 120
2.7. Overall exposure (combined for all relevant emission/release
sources
2.7.1. Human health (combined for all exposure routes)
The critical effects associated with exposure to methyl acrylate are local effects (dermal sensitization and
respiratory irritation) and local effects from different exposure routes are not cumulative. The worker
exposure scenarios presented represent different industrial processes that would typically occur at different
facilities, therefore it is not appropriate to combine these scenarios. Regarding potential exposure in non-
industrial applications, methyl acrylate completely reacts (less than 0.1 wt% remains) during use; therefore,
development of exposure scenarios covering downstream uses (i.e., professional use, consumer use, service
life, waste treatment) are not required and have not been conducted for this assessment.
2.7.2. Environment (combined for all emission sources)
Compartments:
(REGIONAL) RCR
Freshwater 6.80E-02
Marine water 8.05E-02
Freshwater sediment 5.89E-02
Marine water sediment 7.07E-02
Soil [Natural Soil (Total)] 1.38E-05
END OF SDS