Sense of smell

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SENSE OF SMELL EXPERT VISION ACADEMY

description

For SSC-II & HSSC-II

Transcript of Sense of smell

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SENSE OF SMELL

EXPERT VISION ACADEMY

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Smell

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Chemical Senses: Taste and Smell

Both senses use chemoreceptors Stimulated by chemicals Taste has four types of receptors Smell can differentiate a large range of

chemicals Both senses complement each other and

respond to many of the same stimuli Olfaction (smell) and gustation (taste) Both project to cerebral cortex & limbic

system Evokes strong emotional reactions

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Olfactory organs•Contain olfactory receptors and supporting epithelial cells•Cover parts of nasal cavity and a portion of the nasal septum

Olfactory receptors•Chemoreceptors•Respond to chemicals dissolved in liquids

Olfactory Epithelium•Located on roof of nasal cavity•Contain olfactory receptor cells with columnar supporting cells•Covered by mucous to trap airborne molecules

Sense of Smell

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Olfactory Epithelium

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Cells of the Olfactory Membrane

Olfactory receptors bipolar neurons with

cilia or olfactory hairs Supporting cells

columnar epithelium Basal cells = stem cells

replace receptors monthly

Olfactory glands produce mucus

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Sense of Smell

Air entering the nasal cavity must make a hairpin turn to stimulate the olfactory receptors before entering the respiratory passageway below

Sniffing also brings the air superiorly across the olfactory

epithelium intensifies the smell

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Olfactory tract

Olfactory bulb

(a)

Nasalconchae

Route ofinhaled air

Olfactoryepithelium

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Mitral cell (output cell)

Olfactorygland

Olfactorytract

Olfactoryepithelium

Filaments of olfactory nerve

Cribriform plate of ethmoid bone

Lamina propria connective tissue

Basal cell

Supporting cell

Dendrite

Olfactory cilia

Olfactory bulbGlomeruli

Axon

Olfactory receptor cell

Mucus

Route of inhaled aircontaining odor molecules(b)

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Olfactory Cells

Dendrites of each olfactory cell called olfactory cilia

extend into the nasal cavity

Olfactory axons project upward through the foramina in the

cribriform plate of the ethmoid bone of the skull synapse on neurons within the olfactory nerve

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Physiology of Smell

Series of events the chemical must be volatile

it must be in the gaseous state as it enters the nasal cavity

the chemical must be water soluble so that it can dissolve in the fluid containing the olfactory

epithelium the dissolved chemicals stimulate the olfactory

receptors by binding to protein receptors in olfactory cilium membranes

the generation of APs in the olfactory cells an impulse travels through the olfactory cell axons to

the olfactory nerve where the smell sensation is transmitted to the brain

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OLFACTORY PATHWAY

As air enters the nasal passageway the level of odor-producing chemicals dissolve in the mucus membrane

With in the mucus membrane the olfactory cilia capture the chemicals

After reaching a threshold level it is passed to the olfactory nerves located in the olfactory bulb

The impulse passes through the olfactory tract and into the thalamic and olfactory centers of the brain for interpretation, integration, and memory storage.

The sense of smell can create powerful and long-lasting memories. That often persist from early childhood to death

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Olfactory Nerve Pathways

Olfactory receptor fibers synapse with neurons in the olfactory bulbs (cranial nerve I).

Impulses travel along the olfactory tracts Impulses are interpreted in olfactory cortex. Olfactory receptor neurons are in direct contact with

the environment and can be replaced if damaged. Olfactory receptors undergo sensory adaptation

rapidly Sense of smell drops by 50% within a second after

stimulation

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Transmission of smell signals to CNS

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Abnormalities

Anosmia – absence of sense of smell

Hyposmia – diminished olfactory sensitivity

Dysosmia – distorted sense of smell

More than 75% of humans over the age of 80 have an impaired ability to identify smells

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Anosmia

Absence of the sense of smell

Trauma Colds or allergies producing excessive

mucus Polyps causing blockage 1/3 are from zinc deficiency